Alzheimer’s Disease Research : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift / / by Christian Behl |
Autore | Behl Christian |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (XXV, 652 p. 116 illus., 107 illus. in color.) |
Disciplina |
612.8
616.83110072 |
Soggetto topico |
Neurosciences
Neurology Nervous system—Diseases Cognitive neuroscience Neurophysiology Learning—Physiological aspects Memory—Physiological aspects Neuroscience Neurological Disorders Cognitive Neuroscience Learning and Memory |
ISBN | 3-031-31570-7 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change". |
Record Nr. | UNINA-9910734833403321 |
Behl Christian | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Atlas of Sleep Medicine / / edited by Robert J. Thomas, Sushanth Bhat, Sudhansu Chokroverty |
Edizione | [3rd ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (797 pages) |
Disciplina |
616.8
616.8498 |
Altri autori (Persone) |
ThomasRobert J (Professor of medicine)
BhatSushanth ChokrovertySudhansu |
Soggetto topico |
Neurology
Respiratory organs - Diseases Psychiatry Nervous system - Diseases Otorhinolaryngology Cardiology Pneumology Neurological Disorders |
ISBN | 3-031-34625-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1 Introduction, Robert J. Thomas, Sushanth Bhat, Sudhansu Chokroverty -- Section I. Basic Science -- 2 Neuronal Circuits, Anatomical Substrates, and Mechanism of Sleep-Wakefulness, Sudhansu Chokroverty, Sushanth Bhat, Robert J. Thomas -- Section II. Laboratory Techniques -- 3 Polysomnographic Recording Technique, Sudhansu Chokroverty, Sushanth Bhat -- 4 Hypnogram and Compliance Graph Analysis, Robert J. Thomas, Sudhansu Chokroverty, Sushanth Bhat -- 5 Electroencephalograph for the Sleep Specialist, Sudhansu Chokroverty, Eli S. Neiman, Sushanth Bhat -- 6 Odds Ratio Product (ORP): Description and Implications to Understanding and Management of Sleep Disorders, Magdy Younes -- 7 Sleep Stage Scoring, Raman K. Malhotra, Alon Y. Avidan -- 8 Sleep-Disordered Breathing: Scoring, Robert J. Thomas, Sudhansu Chokroverty, Federica Provini, Sushanth Bhat -- 9 Upper Airway Radiology, Richard J. Schwab, Andrew Wiemken -- Section III. Other Sleep Techniques -- 10 Multiple Sleep Latency Test (MSLT) and Maintenance of Wakefulness Test (MWT), Sushanth Bhat, Stacey D. Elkhatib-Smidt, Sudhansu Chokroverty -- 11 Actigraphy, Marco Zucconi, Samantha Mombelli -- 12 Cyclic Alternating Pattern (CAP): Scoring Rules and Clinical Applications, Liborio Parrino, Irene Pollara, Francesco Rausa, Marcello Luigi Salvatelli -- 13 Recommendations for Practical Use of Pulse Transit Time as a Tool for Respiratory Effort Measurements During Sleep and Microarousal Recognition, Jean-Louis Pepin, Sébastien Baillieul, Renaud Tamisier -- 14 Peripheral Arterial Tonometry, Robert J. Thomas -- 15 EEG Spectrograms, Robert J. Thomas, Haoqi Sun -- 16 Cardiopulmonary Coupling, Robert J. Thomas -- 17 Drug-Induced Sleep Endoscopy, Phillip Huyett -- 18 Upper Airway Endotypes, Andrew Wellman, Ran R. Liu -- 19 Autonomic Function Testing Including Autonomic Nervous System and Sleep Interaction, Sudhansu Chokroverty, Sushanth Bhat -- 20 Scoring Techniques for Sleep-Related Movements, Ambra Stefani, Birgit Högl, Raffaele Ferri -- 21 Artificial Intelligence in Sleep Medicine, Haoqi Sun, Wolfgang Ganglberger, M. Brandon Westover, Robert J. Thomas -- 22 Neuroimaging Techniques, Zara Duquette, Nathan Cross, Aurore A. Perrault, Pierre Maquet, Martin Desseilles, Thien Thanh Dang-Vu -- 23 High-Resolution EEG Characterization of Sleep Neurophysiology, Shijing Zhou, Kyle Morgan, Evan Hathaway, Roma Shusterman, Phan Luu, Miranda Lim, Ruth Benca, Don M. Tucker -- 24 Intracranial EEG/MEG Recording and Sleep Medicine, Richard A. Wennberg -- 25 Pictorial Diagnosis of Circadian Rhythm Sleep-Wake Disorders, Sabra M. Abbott, Roneil Malkani, Phyllis C. Zee -- 26 Consumer Sleep Technology: Wearables and Nearables, Sushanth Bhat, Liudmila Lysenko -- Section IV. Clinical Aspects -- 27 Motor Disorders in Sleep, Sushanth Bhat, Liudmila Lysenko, Stacey D. Elkhatib Smidt, Federica Provini, Marco Zucconi, Mauro Manconi, Sudhansu Chokroverty -- 28 Cardiac Arrhythmias, Robert J. Thomas, Sudhansu Chokroverty, Sushanth Bhat -- 29 Sleep and Epilepsy, Lino Nobili, Angelica Montini, Marco Zucconi, Sudhansu Chokroverty, Federica Provini -- 30 Sleep Dysfunction and Sleep-Disordered Breathing in Miscellaneous Neurological Disorders, Sudhansu Chokroverty, Sushanth Bhat, Federica Provini, Greta Mainieri -- 31 Atypical PSG Patterns, Sudhansu Chokroverty, Sushanth Bhat, Robert J. Thomas -- Section V. Therapy in Sleep-Disordered Breathing: Non-invasive -- 32 PAP, Bilevel, APAP, High and Low Loop Gain Syndromes, Robert J. Thomas -- 33 Adaptive Servo Ventilation, Robert J. Thomas -- 34 Oral Appliances for Obstructive Sleep Apnea Syndrome (OSAS) Therapy, Fernanda R. Almeida, Mona M. Hamoda -- Section VI. Therapy in Sleep-Disordered Breathing: Invasive -- 35 Neurostimulation and Sleep Apnea, Robert J. Thomas -- 36 Upper Airway Surgery for Obstructive Sleep Apnea, John A. Fleetham -- Section VII. Pediatric Sleep Medicine (Clinical and Laboratory Techniques) -- 37 Pediatric Polysomnography, Jisu Han, Alexandra Schwarz, Stacey D. Elkhatib Smidt, Timothy F. Hoban -- Section VIII. Video Vignettes -- 38 Sleep Disturbances in Autoimmune Encephalitis, Margaret S. Blattner -- 39 Video-Clinical (SHE, FFI, RBD, and Others), Federica Provini, Greta Mainieri -- 40 Narcolepsy: Unequivocal Diagnosis After Split-screen, Video-polysomnographic Analysis of a Prolonged Cataplectic Attack, Mark Eric Dyken, Deborah C. Lin-Dyken, Jason Maxfield -- 41 Obstructive Sleep Apnea Associated with Cerebral Hypoxemia, Mark Eric Dyken, Christine L. Glenn, George B. Richerson -- 42 The REM Sleep Behavior Disorder Leading to a Subdural Hemorrhage, Mark Eric Dyken, Deborah C. Lin-Dyken, Mark Raymond Dyken -- 43 Isolated Sleep Paralysis: An REM-“Sleep” Polysomnographic Phenomenon, As Documented With Simultaneous Clinical and Electrophysiologic Assessment, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 44 Confusional Arousal, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 45 Sleepwalking, Mark Eric Dyken, Deborah C. Lin-Dyken, Siddharth Bajpai -- 46 Hypnagogic Hallucination, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 47 Sleep Terrors, Mark Eric Dyken, Deborah C. Lin-Dyken, Jeffrey Boyle -- 48 Adult Seizure from REM Sleep After Obstructive Apnea, Mark Eric Dyken, Mark Raymond Dyken -- 49 Pediatric Sleep-Related Seizure with Obstructive Apnea, Mark Eric Dyken, Mark Raymond Dyken -- 50 Nocturnal Frontal Lobe Epilepsy, Mark Eric Dyken, Mark Raymond Dyken -- 51 Sleep-Related Bruxism, Mark Eric Dyken, Mark Raymond Dyken -- 52 Sleep-Related Eating Disorder, Mark Eric Dyken, Mark Raymond Dyken -- 53 Sleep-Related Rhythmic Movement Disorder, Mark Eric Dyken, Mark Raymond Dyken -- 54 Sleep-Breathing Dynamics, Robert J. Thomas -- Section IX. Epilogue -- 55 Epilogue, Sudhansu Chokroverty, Robert J. Thomas, Sushanth Bhat. |
Record Nr. | UNINA-9910760253503321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Challenging Assumptions Around Dementia [[electronic resource] ] : User-led Research and Untold Stories / / by Rosalie Ashworth, Sue Fyvel, Alyson Hill, Chris Maddocks, Masood Qureshi, David Ross, Stuart Hay, Martin Robertson, Willy Gilder, Winnie Henry, Myra Lamont, Agnes Houston, Fred S. Wilson |
Autore | Ashworth Rosalie |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023 |
Descrizione fisica | 1 online resource (154 pages) |
Disciplina | 616.83 |
Altri autori (Persone) |
FyvelSue
HillAlyson MaddocksChris QureshiMasood RossDavid HayStuart RobertsonMartin GilderWilly HenryWinnie |
Soggetto topico |
Geriatrics
Clinical psychology Nervous system - Diseases Mental health Clinical health psychology Psychology - Methodology Clinical Psychology Neurological Disorders Mental Health Health Psychology Psychological Methods Demència Assaigs clínics Testimonis |
Soggetto genere / forma | Llibres electrònics |
ISBN | 3-031-27223-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 1. Coproducing a book on dementia research -- 2. Taking part in Alzheimer’s disease research -- 3. Taking part in Vascular dementia research -- 4. Taking part in Fronto-Temporal dementia research -- 5. Taking part in Parkinson’s dementia research -- 6. Taking part in dementia with lewy bodies research -- 7. Taking part in PCA dementia research -- 8. Lessons for future research in dementia. |
Record Nr. | UNINA-9910737295903321 |
Ashworth Rosalie | ||
Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Curcumin and Neurodegenerative Diseases [[electronic resource] ] : From Traditional to Translational Medicines / / edited by Mahendra Rai, Chistiane M. Feitosa |
Autore | Rai Mahendra |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (483 pages) |
Disciplina | 616.8 |
Altri autori (Persone) | FeitosaChistiane M |
Soggetto topico |
Nervous system - Diseases
Neuropharmacology Medicine - Research Biology - Research Neurological Disorders Translational Research |
ISBN | 981-9977-31-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1_Turmeric in Neurodegenerative diseases: An overview -- Chapter 2_Turmeric: Does it work in neurodegenerative disorders? Separating myth from reality -- Chapter 3_Curcumin bioavailability and constraints of its systemic effects -- Chapter 4_Traditional uses of Turmeric in Neurodegenerative diseases -- Chapter 5_Curcuma from kitchen to cure for neurodegenerative diseases -- Chapter 6_Curcuma used in neurodegenerative diseases: Applications in Ayurveda and Chinese medicines -- Chapter 7_Secondary metabolites of Turmeric (essential oils/extracts) -- Chapter 8_Curcuminoids and Sesquiterpenoids from Curcuma longa Rhizomes: Are they better against cancer or neurodegenerative disorders? - Chapter 9_Curcuma in aging (age-related neurodegenerative diseases) -- Chapter 10_Pharmacokinetics and pharmacodynamics of curcumin -- Chapter 11_Curcuma, curcumin and its nanoparticles in Parkinson's disease -- Chapter 12_Curcumin as a novel therapy for brain diseases -- Chapter 13_Curcumin induced Neuroprotection in cerebral Ischemia -- Chapter 14_Neural Stem cell therapy in combination with Curcumin -- Chapter 15_The use of curcumin in Parkinson’s disease -- Chapter 16_Effects of curcumin on mitochondrial dysfunction in NDs -- Chapter 17_Clinical trials and evidence-based approaches to evaluate curcumin efficacy in human health and disease -- Chapter 18_Nanocurcumin in neurodegenerative -- Chapter 19_Role of Nanocurcumin in Alzheimer’s disease -- Chapter 20_Modification of curcumin scaffold in the search for new effective therapeutic agents against NDs -- Chapter 21_Curcumin-loaded nanoparticles in neurodegenerative diseases -- Chapter 22_Curcumin nanoformulation in neurodegnerative diseases -- Chapter 23_Patents in Curcuma/ Curcumin related to Neurodegenerative diseases. |
Record Nr. | UNINA-9910838272403321 |
Rai Mahendra | ||
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Evidence-based Functional Foods for Prevention of Age-related Diseases [[electronic resource] /] / edited by Surajit Pathak, Antara Banerjee, Asim K. Duttaroy |
Autore | Pathak Surajit |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (378 pages) |
Disciplina | 613.2 |
Altri autori (Persone) |
BanerjeeAntara
DuttaroyAsim K |
Soggetto topico |
Nutrition
Nervous system - Diseases Genomics Neurological Disorders |
ISBN | 981-9905-34-6 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1. Cellular Aging: An Introduction, Principle, Hallmarks, And Aging-Associated Diseases -- Chapter 2. Anti-Oxidant And Anti-Aging Mechanism Of Bioactive Compounds In Modulating The Aging Related Epigenetic Factors -- Chapter 3. Diet-Gene Interactions That Regulate Longevity -- Chapter 4. Antioxidants And Aging -- Chapter 5. Nutrition And Aging Brain -- Chapter 6. Omega 3 And Aging Brain -- Chapter 7. Traditional Foods And Aging -- Chapter 8. Macro Nutrients And Their Roles In Ageing -- Chapter 9.Micronutrient Status Among Adults In The Asia Pacific And Potential Impact On Age-Related Diseases -- Chapter 10. Gut Microbiota And Their Metabolites In Aging -- Chapter 11. Importance Of Functional Foods Against Aging Of Adult Stem Cells -- Chapter 12. Human Skin And Hair Follicle Regeneration, Degeneration, Aging, And Functional Foods -- Chapter 13. Delineating The Role Of Phytochemicals In Targeting Age-Related Cardiovascular Diseases Through The Lens Of Network Medicine -- Chapter 14. Plant -Derived Natural Products Targeting Multiple Pathways As Potential Therapeutics In The Treatment Of Parkinson’S Disease -- Chapter 15. Aging In Indian Women: Health Status -- Chapter 16. Energy Restriction On Cellular And Molecular Mechanisms In Ageing -- Chapter 17. Age-Related Neurodegenerative Diseases -- Chapter 18. Preventive Role Of Nutraceutical Agents Against Aging. . |
Record Nr. | UNINA-9910734859603321 |
Pathak Surajit | ||
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of Neurotoxicity [[electronic resource] /] / edited by Richard M. Kostrzewa |
Edizione | [2nd ed. 2022.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (2551 pages) |
Disciplina | 612.82 |
Soggetto topico |
Neurophysiology
Neurons Nervous system - Diseases Toxicology Neurochemistry Cellular Neuroscience Neurological Disorders Neurotoxicologia |
Soggetto genere / forma | Llibres electrònics |
ISBN |
9783031150807
9783031150791 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Cell Death Processes: Neurons and Glia -- Neuronal Necrosis -- Neuronal Apoptosis -- Autophagy Pathways -- Necrostatin Neuroprotection -- Neuronal Necroptosis, Relation to Neurological Disorders -- Multiple Cell Death Processes in Neurological Disorders -- Micorglia: Neuroprotective and Neurodestructive Propertie.s, - Selective Neurotoxins -- Survey of Selective Neurotoxinx -- RCSN Cell System for Identifying Dopaminergic Neurotoxicity -- Neurotoxicity: A complex multistage process -- Dopaminergic and Noradrenergic Neurotoxins -- Dopamine and L-dopa as Selective Endogenous Neurotoxins., Dopamine D2 Receptor Supersensitivity as a non-Degenerative Neurotoxin -- Trace Amine-Associated Receptor 1 (TAAR1) and Doapmine Receptor Sensitivity -- Dopamine Receptor Supersensitivity to Model Schizophrenia -- Pathophysiology of Obsessive-Compulsive Disorder: Insights from Normal Function and Neurotoxic Effects of Drugs, Infection, and Brain Injury -- Dopamine D3 receptors and schizophrenia / drug addiction -- Tardive Dyskinesia: Outcome of Antipsychotic Treatment and Brain Damage? -- 6-Hydroxydopamine Neurotoxicity in Adult Animal -- 6-Hydroxydopamine Neurotoxicity in Perinatal Animals -- 6-Hydroxydopa in Perinatal and Adult Animals -- MPTP Neurotoxicity Mechanisms -- Dopaminergic and Noradrenergic Neurotoxins and Neurodegenerative Disorders -- anti-NGF -- Advances in Stem Cell Research for Parkinson's Disease -- Autophagy Pathways and Parkinson's Disease -- Regulation of DA Homeostasis and Role of VMAT2 in Parkinson's Disease -- Alpha-Synuclein in Parkinson's Disease -- Dopaminergic Neurons in Parkinson's Disease -- Dopamine Oxidation and Parkinson's Disease -- Neuromelanin and Parkinson's Disease., -Iron-Induced Dopaminergic Cell Death in vivo as a Model of Parkinson's Disease -- Iron Neurotoxicity in Parkinson's Disease -- 6-Hydroxydopamine as Preclinical Model of Parkinson's Disease. - MPTP modeling of Parkinson's Disease -- MPTP: Advances from and Evergreen Neurotoxin. - MPTP and Motor Neurons -- MPTP Neurotoxicity: Actions, Mechanisms, and Animal Modeling of Parkinson's Disease -- Paraquat and Parkinson's Disease -- Rotenone Preclinical Modeling of Parkinson's Disease -- N-Methyl-(R)-Salsolinol and Parkinson's Disease -- Fusion Models and "Fusioning" in Parkinsonism: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline -- Amphetamines as Neurotoxins -- METH Neurotoxicity -- Neurotoxicity of MDMA -- Cocaine influence of A2/D2 receptor heteromers -- Cocaine as a Neurotoxin -- NBOMe Neurotoxicity -- Cathinone Neurotoxicity - several chapters -- Neurotoxic Vulnerability Underlying Schizophrenia Spectrum Disorders -- Molecular Mechanism and Effects of Clostridial Neurotoxins -- Botulinum Neurotoxicity -- ~3 addl subchapters on Botulinum Neurotoxicity -- Neurotoxic Effects, Mechanisms, and Outcome of 192-IgG Saporin -- TRPV1 Activators ("Vanilloids") as Neurotoxins -- Protective Agents in Parkinson's Disease:Caffeine and Adenosine A2A Receptor Antagonists -- Physical Exercise as Intervention in Parkinsonism -- Manganese Neurotoxicity and Parkinson's Disease -- Neuroinflammation and Parkinson's Disease -- Neurotoxicity in Psychostimulant and Opiate Addiction -- Homocysteine and Cerebellar Damage -- Propionic Acid, Modeling of Autism Spectrum Disorders -- 1-Me-TIQ, and endogenous Neuroprotectant -- 5-MeO-DIPT -- 3-MD-Glutaric acid -- 3-NP and Huntington's Disease -- 25C-NBOMe -- M-30 -- Trace amine-associated receptor 1 and neuropsychiatric disorders -- PACAP as a Neuroprotectant -- Doxycycline as a Neuroprotectant -- PCP Modeling Amnesia -- Drug Abuse Neurotoxicity: Alcohol and Nicotine as Developmental Stressors -- Neurotrophic Factors and Ethanol Neurotoxicity -- Salsolinol and Addiction -- Snake Venom Toxins -- Salicylate Ototoxicity -- Serotoninergic Neurotoxins -- Nature of DSP-4-Induced Neurotoxicity -- 5,6- and 5,7-Dihydroxytryptamines as Serotoninergic Neurotoxins -- 2'NH(2)-MPTP: A Serotonin and Norepinephrine Neurotoxin -- Excitotoxins and Excitotoxicity -- Glutamate as a Neurotoxin -- Aspartate as a Neurotoxin -- Concept of Excitotoxicity via Glutamate Receptors -- Glutamate Neurotoxicity, Transport and Alternative Splicing of Transporters -- Excitotoxicity: A Complex Multistage Process Involving Different Mechanisms -- Glutamate Excitotoxicity Relation to Energy Failure -- Ionotropic Receptors in the Central Nervous System and Neurodegenerative Disorders -- Excitotoxicity and Axon Degeneration -- Glutamate Scavengers -- Quinolinate and Related Excitotoxins: Mechanisms of Neurotoxicity and Disease Relevanc -- Domoic Acid as a Neurotoxin -- BOAA and Neurotoxicit -- Endogenous Kynurenic Acid and Neurotoxicity -- Neuroprotection by Kynurenine Metabolites -- BMAA (beta-N-Methylamin -- Ionotropic Glutamate Receptors in Neurodegenerative and Other Disorders -- Okadaic acid modeling of Alzheimer's Disease -- Excitotoxicity in Parkinson's Disease -- Excitotoxicity and the Pathogenesis of Gliomas Excitotoxicity and Epielpsy; Epilepsy re Neurotoxicity Mechs -- Excitotoxicity in Multiple Sclerosis -- Excitotoxicity: Insights into Pathogenesis of AD -- Excitotoxicity and ALS: Insights into Pathogenesis -- Excitotoxicity and Amyotrophic Lateral Sclerosis -- Fungal Neurotoxins and ALS -- Excitotoxicity and Huntington Disease -- Excitotoxicity and Stroke -- Excitotoxicity in HIV Associated Neurocognitive Disordders -- Excitotoxicity and AIDS -- Excitotoxicity and Neuroprotection in Spinal Cord Injury -- Excitotoxicity in the Pathogenesis of Autism -- Cancer-Mediated Excitotoxicity., Excitotoxicity and Depression -- Lead and Excitotoxicity -- Glutamate and Neurodegeneration in the Retina -- Excitotoxicity and Epielpsy -- Seizures, Neurotrophin, Neuronal Death -- Neurodegenerative Aspets of Multiple System Atrophy -- Excitotoxicity in Ischemia and Reperfusion Injury -- Molecular, Cellular, and Behavioural Effects Produced by Perinatal Asphyxia: Neuroprotectants Targeting NMDA Receptor Signaling -- Neuroprotective Strategies in Amyotrophic Lateral Sclerosis Modulation of Neurotransmitory and Neurotrophic Input to Motor Neurons -- Neuroprotection in Demyelinating Diseases: The Therapeutic Potential of the Neurotrophins -- p75NTR: A Molecule with Multiple Functions in Amyloid-beta -- Metabolism and Neurotoxicity -- Neurotrophins and ALS -- Neurotrophic Factors & NeuroAIDS -- Neuroprotection by Poly (ADP-Ribose) Polymerase 1 (PARP-1) Inhibition -- Alzheimer's Disease and Neurotoxic Aspects -- Stem Cell Therapies for Age Associated Neurodegeneration -- Pathogenesis of Alzheimer's Disease -- Experimental Approach to Alzheimer Disease -- Potential Therapeutic Effects of Statins in Alzheimer's Disease -- Excitotoxicity and Alzheimer's Disease: Treatment Challenges -- Amyloid-beta, BDNF, and Mechanism of Neurodegeneration in Alzheimer's Diseases -- Drug Treatments: hopes, challenges -- Cannabinoids and Alzheimer's -- Heavy Metal Neurotoxicity -- Trimethyltin Neurotoxicity -- Mn Neurotoxicity -- MeHG -- Cd Neurotoxicity -- Fe Neurotoxicity -- Organoselenium -- Al Neurotoxicity -- Se Neurotoxicity -- Pb Neurotoxicity -- Cuprizone modelin of Multiple sclerosis. |
Record Nr. | UNINA-9910637715403321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Handbook of Stem Cell Applications [[electronic resource] /] / edited by Khawaja H. Haider |
Edizione | [1st ed. 2024.] |
Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
Descrizione fisica | 1 online resource (167 illus., 47 illus. in color. eReference.) |
Disciplina |
571.6
616.02774 |
Soggetto topico |
Stem cells
Regenerative medicine Nervous system - Diseases Stem Cell Biology Regenerative Medicine and Tissue Engineering Neurological Disorders |
ISBN | 981-9971-19-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chapter 1_ The application of stem cells for the therapy of Parkinson’s disease -- Chapter 2_Stem cell therapy after neurological injuries -- Chapter 3_Strategies of Stem cell therapy in nervous system injuries repair and regeneration -- Chapter 4_Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders -- Chapter 5_Emerging Stem Cell Therapy and Tissue Engineering Approaches in Neurodegenerative Diseases -- Chapter 6_Next Generation of Science with Stem Cell-based Neural Organoids -- Chapter 7_Mesenchymal stem cells for ocular disorders -- Chapter 8_Keratocytes evolution in advanced regenerative corneal therapy with keratoconus -- Chapter 9_Latest advances in mesenchymal stem cell-based therapy of eye diseases -- Chapter 10_Stem cells in ophthalmology: from the bench to the bedside -- Chapter 11_Stem cells in periodontal regeneration -- Chapter 12_Dental pulp stem cells in Endodontics – Advances, applications and challenges -- Chapter 13_Significance of inflammatory milieu during regeneration of periodontal tissues using dental mesenchymal stem cell -- Chapter 14_3D bioprinting in conjunction with bone marrow mesenchymal stem cells for the treatment of bone defects -- Chapter 15_Allogenic Stem Cells: Advances in Knee Osteoarthritis -- Chapter 16_Mesenchymal stem cells for bone and cartilage regeneration: state-of-the-art -- Chapter 17_Clinical trials of cell therapy in muscular dystrophies -- Chapter 18_Scaling Stem Cells to Cure Millions of Patients with Diabetes – Approaches, Technology, and Future Directions -- Chapter 19_Restoring β-cells population through in situ differentiation of the resident pancreatic cells -- Chapter 20_Stem Cell-Based Regenerative Therapies for Functional Endocrine System Organs: Tissue Engineering Applications and Future Strategies -- Chapter 21_Recent advance in regenerativemedicine of the liver and bile duct system by chemically induced liver progenitor cells (CLiPs) -- Chapter 22_Advantages of a novel hepatic stem/progenitor cell population for fibrotic/cirrhotic liver repair and regeneration -- Chapter 23_ Evolving Understanding of Renal Progenitor (Stem) Cells in Renal Physiology and Pathophysiology -- Chapter 24_The regenerative potential of human adult renal stem/progenitor cells -- Chapter 25_Role of Exosomes as a biomarker in cardio-metabolic and renal diseases -- Chapter 26_Renovascular applications of stem cells -- Chapter 27_Reversing the aged Immune system with Stem cells -- Chapter 28_Germline stem cell technology in fertility preservation -- Chapter 29_One-stop shop for salivary gland regeneration and other exocrine organs -- Chapter 30_ Epithelial Stem Cell for Regeneration in Acute and Chronic Airway Injury -- Chapter 31_Genetic Cell Therapy in Anti-Aging Regenerative Cosmetology -- Chapter 32_Polytrauma and Stem Cells -- Chapter 33_The Multifaceted Role of Induced Pluripotent Stem Cells in Pre-Clinical Cardiac Regeneration Research -- Chapter 34_Stem cell-based regenerative medicine therapy in cancer -- Chapter 35_Novel Prognostic and Predictive Biomarkers in Oncology -- Chapter 36_Mesenchymal stem cells, cancer stem cells (CSCs), and circulating tumor cells (CTCs): roles and combinations in tumor growth and dissemination -- Chapter 37_ Participation of mesenchymal stem cell in the tumor process -- Chapter 38_Pre-enrichment of Adipose Tissue Grafts with Adipose Derived Stem Cells: Potential and Limitations -- Chapter 39_Matrix mechanical cues affect cell behavior and tissue regeneration -- Chapter 40_Biophysical regulators of mesenchymal stem cell fate -- Chapter 41_Influence of microbiota of donors and recipients in mesenchymal stem cell behavior regarding epigenetic pattern, stemness and secretome -- Chapter 42_Mesenchymal stem cells as modern off-the-shelf products: From research perspectives to clinical practice -- Chapter 43_Application of single-cell sequencing on stem cell research -- Chapter 44_Proteomics investigations on stem cell-based regenerative medicine -- Chapter 45_Phospholipid metabolism in stem cells and its application to pathological analysis -- Chapter 46_The role of stem cells in exercise enhanced organogenesis and regeneration -- Chapter 47_Mesenchymal stem cell-derived exosomes: A novel remedy for the treatment of Parkinson’s Disease -- Chapter 48_Time of cell injection -- Chapter 49_Novel Preconditioning approach to promote donor cell survival. |
Record Nr. | UNINA-9910845482403321 |
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Mechanisms and Emerging Therapies in Tremor Disorders / / edited by Giuliana Grimaldi, Mario Manto |
Autore | Grimaldi Giuliana |
Edizione | [2nd ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (556 pages) |
Disciplina |
616.8/3
616.8 |
Altri autori (Persone) | MantoMario |
Collana | Contemporary Clinical Neuroscience |
Soggetto topico |
Medicine - Research
Biology - Research Neurology Neurosciences Nervous system - Diseases Biomedical Research Neuroscience Neurological Disorders |
ISBN | 3-031-26128-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor. |
Record Nr. | UNINA-9910754089503321 |
Grimaldi Giuliana | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Medical Neuroanatomy for the Boards and the Clinic [[electronic resource] ] : Finding the Lesion / / by Jonathan Leo |
Autore | Leo Jonathan |
Edizione | [2nd ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (254 pages) |
Disciplina | 745.05 |
Soggetto topico |
Neurology
Neuroanatomy Nervous system - Diseases Neurosciences Nervous system - Surgery Neurological Disorders Neuroscience Neurosurgery |
ISBN | 3-031-41123-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Chapter One: The Three Long Tracts and Spinal Cord Lesions -- Chapter Two: Corticobulbar Tract and Cranial Nerve Motor Nuclei.-Chapter Three: Abducens Nerve Lesions -- Chapter Four: Vestibulocochlear Nerve Lesions Historical Snippet: The Caloric Reflex Test, the Nobel Prize, and a POW -- Chapter Five: Visual Field Lesions Historical Snippet: Lesion Analysis of the Visual System -- Chapter Six: Autonomics and Lesions -- Chapter Seven: Facial Nerve Lesions -- Chapter Eight: Cerebellar Lesions -- Chapter Nine: Basal Ganglia Lesions -- Chapter Ten: Thalamus and Hypothalamus -- Chapter Eleven: Limbic System, Learning, Memory, and How the Brain Works Historical Snippet: Endothelial Derived Relaxing Factor = Nitric Oxide -- Chapter Twelve: Chemical Neuroanatomy Historical Snippet: The Opioid Epidemic in a Nutshell -- Chapter Thirteen: Brainstem Lesions -- Historical Snippet: Proustian Moment -- Chapter Fourteen: Cerebral Cortex Lesions Historical Snippet: London Cabbies and the Hippocampus -- Chapter Fifteen: Neurophysiology Historical Snippet: The Discovery of Acetylcholine and a Dream -- Chapter Sixteen: Neuroanatomy Atlas -- Chapter Seventeen: Lesion and Blood Vessel Test -- Chapter Eighteen: Key Words.-. |
Record Nr. | UNINA-9910754090503321 |
Leo Jonathan | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Medical Neuroanatomy for the Boards and the Clinic : Finding the Lesion / / by Jonathan Leo |
Autore | Leo Jonathan |
Edizione | [1st ed. 2022.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
Descrizione fisica | 1 online resource (156 pages) |
Disciplina | 611.8076 |
Soggetto topico |
Neurology
Neuroanatomy Nervous system - Diseases Neurosciences Nervous system - Surgery Neurological Disorders Neuroscience Neurosurgery Neuroanatomia Malalties del sistema nerviós |
Soggetto genere / forma | Llibres electrònics |
ISBN |
9783030888350
9783030888343 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Chapter One. The Three Long Tracts in the Spinal Cord and Brainstem -- Chapter Two. Spinal Cord -- Chapter Three. Spinal Cord Lesions -- Chapter Four. Nystagmus and Lateral Gaze.-Chapter Five. Vestibulocochlear Nerve -- Chapter Six. Visual Fields -- Chapter Seven. Autonomics -- Chapter Eight. Facial Nerve -- Chapter Nine. Thinking Clinically about the Brainstem -- Chapter Ten. Cerebellum -- Chapter Eleven. Basal Ganglia -- Chapter Twelve. Thalamus -- Chapter Thirteen. Limbic Circuit -- Chapter Fourteen. More on Brainstem Lesions -- Chapter Fifteen. Cranial Nerve Three In-Depth -- Chapter Sixteen. Cerebral Cortex -- Chapter Seventeen. Blood Supply -- Chapter Eighteen. Fibers, Reflexes, and Radiculopathies . |
Record Nr. | UNINA-9910522954103321 |
Leo Jonathan | ||
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|