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Alzheimer’s Disease Research [[electronic resource] ] : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift / / by Christian Behl
Alzheimer’s Disease Research [[electronic resource] ] : What Has Guided Research So Far and Why It Is High Time for a Paradigm Shift / / by Christian Behl
Autore Behl Christian
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (XXV, 652 p. 116 illus., 107 illus. in color.)
Disciplina 612.8
Soggetto topico Neurosciences
Neurology
Nervous system—Diseases
Cognitive neuroscience
Neurophysiology
Learning—Physiological aspects
Memory—Physiological aspects
Neuroscience
Neurological Disorders
Cognitive Neuroscience
Learning and Memory
ISBN 3-031-31570-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
Record Nr. UNINA-9910734833403321
Behl Christian  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Atlas of Sleep Medicine [[electronic resource] /] / edited by Robert J. Thomas, Sushanth Bhat, Sudhansu Chokroverty
Atlas of Sleep Medicine [[electronic resource] /] / edited by Robert J. Thomas, Sushanth Bhat, Sudhansu Chokroverty
Edizione [3rd ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (797 pages)
Disciplina 616.8
Altri autori (Persone) ThomasRobert J (Professor of medicine)
BhatSushanth
ChokrovertySudhansu
Soggetto topico Neurology
Respiratory organs - Diseases
Psychiatry
Nervous system - Diseases
Otorhinolaryngology
Cardiology
Pneumology
Neurological Disorders
ISBN 3-031-34625-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 Introduction, Robert J. Thomas, Sushanth Bhat, Sudhansu Chokroverty -- Section I. Basic Science -- 2 Neuronal Circuits, Anatomical Substrates, and Mechanism of Sleep-Wakefulness, Sudhansu Chokroverty, Sushanth Bhat, Robert J. Thomas -- Section II. Laboratory Techniques -- 3 Polysomnographic Recording Technique, Sudhansu Chokroverty, Sushanth Bhat -- 4 Hypnogram and Compliance Graph Analysis, Robert J. Thomas, Sudhansu Chokroverty, Sushanth Bhat -- 5 Electroencephalograph for the Sleep Specialist, Sudhansu Chokroverty, Eli S. Neiman, Sushanth Bhat -- 6 Odds Ratio Product (ORP): Description and Implications to Understanding and Management of Sleep Disorders, Magdy Younes -- 7 Sleep Stage Scoring, Raman K. Malhotra, Alon Y. Avidan -- 8 Sleep-Disordered Breathing: Scoring, Robert J. Thomas, Sudhansu Chokroverty, Federica Provini, Sushanth Bhat -- 9 Upper Airway Radiology, Richard J. Schwab, Andrew Wiemken -- Section III. Other Sleep Techniques -- 10 Multiple Sleep Latency Test (MSLT) and Maintenance of Wakefulness Test (MWT), Sushanth Bhat, Stacey D. Elkhatib-Smidt, Sudhansu Chokroverty -- 11 Actigraphy, Marco Zucconi, Samantha Mombelli -- 12 Cyclic Alternating Pattern (CAP): Scoring Rules and Clinical Applications, Liborio Parrino, Irene Pollara, Francesco Rausa, Marcello Luigi Salvatelli -- 13 Recommendations for Practical Use of Pulse Transit Time as a Tool for Respiratory Effort Measurements During Sleep and Microarousal Recognition, Jean-Louis Pepin, Sébastien Baillieul, Renaud Tamisier -- 14 Peripheral Arterial Tonometry, Robert J. Thomas -- 15 EEG Spectrograms, Robert J. Thomas, Haoqi Sun -- 16 Cardiopulmonary Coupling, Robert J. Thomas -- 17 Drug-Induced Sleep Endoscopy, Phillip Huyett -- 18 Upper Airway Endotypes, Andrew Wellman, Ran R. Liu -- 19 Autonomic Function Testing Including Autonomic Nervous System and Sleep Interaction, Sudhansu Chokroverty, Sushanth Bhat -- 20 Scoring Techniques for Sleep-Related Movements, Ambra Stefani, Birgit Högl, Raffaele Ferri -- 21 Artificial Intelligence in Sleep Medicine, Haoqi Sun, Wolfgang Ganglberger, M. Brandon Westover, Robert J. Thomas -- 22 Neuroimaging Techniques, Zara Duquette, Nathan Cross, Aurore A. Perrault, Pierre Maquet, Martin Desseilles, Thien Thanh Dang-Vu -- 23 High-Resolution EEG Characterization of Sleep Neurophysiology, Shijing Zhou, Kyle Morgan, Evan Hathaway, Roma Shusterman, Phan Luu, Miranda Lim, Ruth Benca, Don M. Tucker -- 24 Intracranial EEG/MEG Recording and Sleep Medicine, Richard A. Wennberg -- 25 Pictorial Diagnosis of Circadian Rhythm Sleep-Wake Disorders, Sabra M. Abbott, Roneil Malkani, Phyllis C. Zee -- 26 Consumer Sleep Technology: Wearables and Nearables, Sushanth Bhat, Liudmila Lysenko -- Section IV. Clinical Aspects -- 27 Motor Disorders in Sleep, Sushanth Bhat, Liudmila Lysenko, Stacey D. Elkhatib Smidt, Federica Provini, Marco Zucconi, Mauro Manconi, Sudhansu Chokroverty -- 28 Cardiac Arrhythmias, Robert J. Thomas, Sudhansu Chokroverty, Sushanth Bhat -- 29 Sleep and Epilepsy, Lino Nobili, Angelica Montini, Marco Zucconi, Sudhansu Chokroverty, Federica Provini -- 30 Sleep Dysfunction and Sleep-Disordered Breathing in Miscellaneous Neurological Disorders, Sudhansu Chokroverty, Sushanth Bhat, Federica Provini, Greta Mainieri -- 31 Atypical PSG Patterns, Sudhansu Chokroverty, Sushanth Bhat, Robert J. Thomas -- Section V. Therapy in Sleep-Disordered Breathing: Non-invasive -- 32 PAP, Bilevel, APAP, High and Low Loop Gain Syndromes, Robert J. Thomas -- 33 Adaptive Servo Ventilation, Robert J. Thomas -- 34 Oral Appliances for Obstructive Sleep Apnea Syndrome (OSAS) Therapy, Fernanda R. Almeida, Mona M. Hamoda -- Section VI. Therapy in Sleep-Disordered Breathing: Invasive -- 35 Neurostimulation and Sleep Apnea, Robert J. Thomas -- 36 Upper Airway Surgery for Obstructive Sleep Apnea, John A. Fleetham -- Section VII. Pediatric Sleep Medicine (Clinical and Laboratory Techniques) -- 37 Pediatric Polysomnography, Jisu Han, Alexandra Schwarz, Stacey D. Elkhatib Smidt, Timothy F. Hoban -- Section VIII. Video Vignettes -- 38 Sleep Disturbances in Autoimmune Encephalitis, Margaret S. Blattner -- 39 Video-Clinical (SHE, FFI, RBD, and Others), Federica Provini, Greta Mainieri -- 40 Narcolepsy: Unequivocal Diagnosis After Split-screen, Video-polysomnographic Analysis of a Prolonged Cataplectic Attack, Mark Eric Dyken, Deborah C. Lin-Dyken, Jason Maxfield -- 41 Obstructive Sleep Apnea Associated with Cerebral Hypoxemia, Mark Eric Dyken, Christine L. Glenn, George B. Richerson -- 42 The REM Sleep Behavior Disorder Leading to a Subdural Hemorrhage, Mark Eric Dyken, Deborah C. Lin-Dyken, Mark Raymond Dyken -- 43 Isolated Sleep Paralysis: An REM-“Sleep” Polysomnographic Phenomenon, As Documented With Simultaneous Clinical and Electrophysiologic Assessment, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 44 Confusional Arousal, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 45 Sleepwalking, Mark Eric Dyken, Deborah C. Lin-Dyken, Siddharth Bajpai -- 46 Hypnagogic Hallucination, Mark Eric Dyken, Deborah C. Lin-Dyken, Nivedita Jerath -- 47 Sleep Terrors, Mark Eric Dyken, Deborah C. Lin-Dyken, Jeffrey Boyle -- 48 Adult Seizure from REM Sleep After Obstructive Apnea, Mark Eric Dyken, Mark Raymond Dyken -- 49 Pediatric Sleep-Related Seizure with Obstructive Apnea, Mark Eric Dyken, Mark Raymond Dyken -- 50 Nocturnal Frontal Lobe Epilepsy, Mark Eric Dyken, Mark Raymond Dyken -- 51 Sleep-Related Bruxism, Mark Eric Dyken, Mark Raymond Dyken -- 52 Sleep-Related Eating Disorder, Mark Eric Dyken, Mark Raymond Dyken -- 53 Sleep-Related Rhythmic Movement Disorder, Mark Eric Dyken, Mark Raymond Dyken -- 54 Sleep-Breathing Dynamics, Robert J. Thomas -- Section IX. Epilogue -- 55 Epilogue, Sudhansu Chokroverty, Robert J. Thomas, Sushanth Bhat.
Record Nr. UNINA-9910760253503321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Challenging Assumptions Around Dementia [[electronic resource] ] : User-led Research and Untold Stories / / by Rosalie Ashworth, Sue Fyvel, Alyson Hill, Chris Maddocks, Masood Qureshi, David Ross, Stuart Hay, Martin Robertson, Willy Gilder, Winnie Henry, Myra Lamont, Agnes Houston, Fred S. Wilson
Challenging Assumptions Around Dementia [[electronic resource] ] : User-led Research and Untold Stories / / by Rosalie Ashworth, Sue Fyvel, Alyson Hill, Chris Maddocks, Masood Qureshi, David Ross, Stuart Hay, Martin Robertson, Willy Gilder, Winnie Henry, Myra Lamont, Agnes Houston, Fred S. Wilson
Autore Ashworth Rosalie
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023
Descrizione fisica 1 online resource (154 pages)
Disciplina 616.83
Altri autori (Persone) FyvelSue
HillAlyson
MaddocksChris
QureshiMasood
RossDavid
HayStuart
RobertsonMartin
GilderWilly
HenryWinnie
Soggetto topico Geriatrics
Clinical psychology
Nervous system - Diseases
Mental health
Clinical health psychology
Psychology - Methodology
Clinical Psychology
Neurological Disorders
Mental Health
Health Psychology
Psychological Methods
Demència
Assaigs clínics
Testimonis
Soggetto genere / forma Llibres electrònics
ISBN 3-031-27223-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Coproducing a book on dementia research -- 2. Taking part in Alzheimer’s disease research -- 3. Taking part in Vascular dementia research -- 4. Taking part in Fronto-Temporal dementia research -- 5. Taking part in Parkinson’s dementia research -- 6. Taking part in dementia with lewy bodies research -- 7. Taking part in PCA dementia research -- 8. Lessons for future research in dementia.
Record Nr. UNINA-9910737295903321
Ashworth Rosalie  
Cham : , : Springer International Publishing : , : Imprint : Palgrave Macmillan, , 2023
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Curcumin and Neurodegenerative Diseases [[electronic resource] ] : From Traditional to Translational Medicines / / edited by Mahendra Rai, Chistiane M. Feitosa
Curcumin and Neurodegenerative Diseases [[electronic resource] ] : From Traditional to Translational Medicines / / edited by Mahendra Rai, Chistiane M. Feitosa
Autore Rai Mahendra
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (483 pages)
Disciplina 616.8
Altri autori (Persone) FeitosaChistiane M
Soggetto topico Nervous system - Diseases
Neuropharmacology
Medicine - Research
Biology - Research
Neurological Disorders
Translational Research
ISBN 981-9977-31-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1_Turmeric in Neurodegenerative diseases: An overview -- Chapter 2_Turmeric: Does it work in neurodegenerative disorders? Separating myth from reality -- Chapter 3_Curcumin bioavailability and constraints of its systemic effects -- Chapter 4_Traditional uses of Turmeric in Neurodegenerative diseases -- Chapter 5_Curcuma from kitchen to cure for neurodegenerative diseases -- Chapter 6_Curcuma used in neurodegenerative diseases: Applications in Ayurveda and Chinese medicines -- Chapter 7_Secondary metabolites of Turmeric (essential oils/extracts) -- Chapter 8_Curcuminoids and Sesquiterpenoids from Curcuma longa Rhizomes: Are they better against cancer or neurodegenerative disorders? - Chapter 9_Curcuma in aging (age-related neurodegenerative diseases) -- Chapter 10_Pharmacokinetics and pharmacodynamics of curcumin -- Chapter 11_Curcuma, curcumin and its nanoparticles in Parkinson's disease -- Chapter 12_Curcumin as a novel therapy for brain diseases -- Chapter 13_Curcumin induced Neuroprotection in cerebral Ischemia -- Chapter 14_Neural Stem cell therapy in combination with Curcumin -- Chapter 15_The use of curcumin in Parkinson’s disease -- Chapter 16_Effects of curcumin on mitochondrial dysfunction in NDs -- Chapter 17_Clinical trials and evidence-based approaches to evaluate curcumin efficacy in human health and disease -- Chapter 18_Nanocurcumin in neurodegenerative -- Chapter 19_Role of Nanocurcumin in Alzheimer’s disease -- Chapter 20_Modification of curcumin scaffold in the search for new effective therapeutic agents against NDs -- Chapter 21_Curcumin-loaded nanoparticles in neurodegenerative diseases -- Chapter 22_Curcumin nanoformulation in neurodegnerative diseases -- Chapter 23_Patents in Curcuma/ Curcumin related to Neurodegenerative diseases.
Record Nr. UNINA-9910838272403321
Rai Mahendra  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
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Evidence-based Functional Foods for Prevention of Age-related Diseases [[electronic resource] /] / edited by Surajit Pathak, Antara Banerjee, Asim K. Duttaroy
Evidence-based Functional Foods for Prevention of Age-related Diseases [[electronic resource] /] / edited by Surajit Pathak, Antara Banerjee, Asim K. Duttaroy
Autore Pathak Surajit
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (378 pages)
Disciplina 613.2
Altri autori (Persone) BanerjeeAntara
DuttaroyAsim K
Soggetto topico Nutrition
Nervous system - Diseases
Genomics
Neurological Disorders
ISBN 981-9905-34-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. Cellular Aging: An Introduction, Principle, Hallmarks, And Aging-Associated Diseases -- Chapter 2. Anti-Oxidant And Anti-Aging Mechanism Of Bioactive Compounds In Modulating The Aging Related Epigenetic Factors -- Chapter 3. Diet-Gene Interactions That Regulate Longevity -- Chapter 4. Antioxidants And Aging -- Chapter 5. Nutrition And Aging Brain -- Chapter 6. Omega 3 And Aging Brain -- Chapter 7. Traditional Foods And Aging -- Chapter 8. Macro Nutrients And Their Roles In Ageing -- Chapter 9.Micronutrient Status Among Adults In The Asia Pacific And Potential Impact On Age-Related Diseases -- Chapter 10. Gut Microbiota And Their Metabolites In Aging -- Chapter 11. Importance Of Functional Foods Against Aging Of Adult Stem Cells -- Chapter 12. Human Skin And Hair Follicle Regeneration, Degeneration, Aging, And Functional Foods -- Chapter 13. Delineating The Role Of Phytochemicals In Targeting Age-Related Cardiovascular Diseases Through The Lens Of Network Medicine -- Chapter 14. Plant -Derived Natural Products Targeting Multiple Pathways As Potential Therapeutics In The Treatment Of Parkinson’S Disease -- Chapter 15. Aging In Indian Women: Health Status -- Chapter 16. Energy Restriction On Cellular And Molecular Mechanisms In Ageing -- Chapter 17. Age-Related Neurodegenerative Diseases -- Chapter 18. Preventive Role Of Nutraceutical Agents Against Aging. .
Record Nr. UNINA-9910734859603321
Pathak Surajit  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
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Handbook of Neurotoxicity [[electronic resource] /] / edited by Richard M. Kostrzewa
Handbook of Neurotoxicity [[electronic resource] /] / edited by Richard M. Kostrzewa
Edizione [2nd ed. 2022.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Descrizione fisica 1 online resource (2551 pages)
Disciplina 612.82
Soggetto topico Neurophysiology
Neurons
Nervous system - Diseases
Toxicology
Neurochemistry
Cellular Neuroscience
Neurological Disorders
Neurotoxicologia
Soggetto genere / forma Llibres electrònics
ISBN 9783031150807
9783031150791
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cell Death Processes: Neurons and Glia -- Neuronal Necrosis -- Neuronal Apoptosis -- Autophagy Pathways -- Necrostatin Neuroprotection -- Neuronal Necroptosis, Relation to Neurological Disorders -- Multiple Cell Death Processes in Neurological Disorders -- Micorglia: Neuroprotective and Neurodestructive Propertie.s, - Selective Neurotoxins -- Survey of Selective Neurotoxinx -- RCSN Cell System for Identifying Dopaminergic Neurotoxicity -- Neurotoxicity: A complex multistage process -- Dopaminergic and Noradrenergic Neurotoxins -- Dopamine and L-dopa as Selective Endogenous Neurotoxins., Dopamine D2 Receptor Supersensitivity as a non-Degenerative Neurotoxin -- Trace Amine-Associated Receptor 1 (TAAR1) and Doapmine Receptor Sensitivity -- Dopamine Receptor Supersensitivity to Model Schizophrenia -- Pathophysiology of Obsessive-Compulsive Disorder: Insights from Normal Function and Neurotoxic Effects of Drugs, Infection, and Brain Injury -- Dopamine D3 receptors and schizophrenia / drug addiction -- Tardive Dyskinesia: Outcome of Antipsychotic Treatment and Brain Damage? -- 6-Hydroxydopamine Neurotoxicity in Adult Animal -- 6-Hydroxydopamine Neurotoxicity in Perinatal Animals -- 6-Hydroxydopa in Perinatal and Adult Animals -- MPTP Neurotoxicity Mechanisms -- Dopaminergic and Noradrenergic Neurotoxins and Neurodegenerative Disorders -- anti-NGF -- Advances in Stem Cell Research for Parkinson's Disease -- Autophagy Pathways and Parkinson's Disease -- Regulation of DA Homeostasis and Role of VMAT2 in Parkinson's Disease -- Alpha-Synuclein in Parkinson's Disease -- Dopaminergic Neurons in Parkinson's Disease -- Dopamine Oxidation and Parkinson's Disease -- Neuromelanin and Parkinson's Disease., -Iron-Induced Dopaminergic Cell Death in vivo as a Model of Parkinson's Disease -- Iron Neurotoxicity in Parkinson's Disease -- 6-Hydroxydopamine as Preclinical Model of Parkinson's Disease. - MPTP modeling of Parkinson's Disease -- MPTP: Advances from and Evergreen Neurotoxin. - MPTP and Motor Neurons -- MPTP Neurotoxicity: Actions, Mechanisms, and Animal Modeling of Parkinson's Disease -- Paraquat and Parkinson's Disease -- Rotenone Preclinical Modeling of Parkinson's Disease -- N-Methyl-(R)-Salsolinol and Parkinson's Disease -- Fusion Models and "Fusioning" in Parkinsonism: 1-Benzyl-1,2,3,4-tetrahydroisoquinoline -- Amphetamines as Neurotoxins -- METH Neurotoxicity -- Neurotoxicity of MDMA -- Cocaine influence of A2/D2 receptor heteromers -- Cocaine as a Neurotoxin -- NBOMe Neurotoxicity -- Cathinone Neurotoxicity - several chapters -- Neurotoxic Vulnerability Underlying Schizophrenia Spectrum Disorders -- Molecular Mechanism and Effects of Clostridial Neurotoxins -- Botulinum Neurotoxicity -- ~3 addl subchapters on Botulinum Neurotoxicity -- Neurotoxic Effects, Mechanisms, and Outcome of 192-IgG Saporin -- TRPV1 Activators ("Vanilloids") as Neurotoxins -- Protective Agents in Parkinson's Disease:Caffeine and Adenosine A2A Receptor Antagonists -- Physical Exercise as Intervention in Parkinsonism -- Manganese Neurotoxicity and Parkinson's Disease -- Neuroinflammation and Parkinson's Disease -- Neurotoxicity in Psychostimulant and Opiate Addiction -- Homocysteine and Cerebellar Damage -- Propionic Acid, Modeling of Autism Spectrum Disorders -- 1-Me-TIQ, and endogenous Neuroprotectant -- 5-MeO-DIPT -- 3-MD-Glutaric acid -- 3-NP and Huntington's Disease -- 25C-NBOMe -- M-30 -- Trace amine-associated receptor 1 and neuropsychiatric disorders -- PACAP as a Neuroprotectant -- Doxycycline as a Neuroprotectant -- PCP Modeling Amnesia -- Drug Abuse Neurotoxicity: Alcohol and Nicotine as Developmental Stressors -- Neurotrophic Factors and Ethanol Neurotoxicity -- Salsolinol and Addiction -- Snake Venom Toxins -- Salicylate Ototoxicity -- Serotoninergic Neurotoxins -- Nature of DSP-4-Induced Neurotoxicity -- 5,6- and 5,7-Dihydroxytryptamines as Serotoninergic Neurotoxins -- 2'NH(2)-MPTP: A Serotonin and Norepinephrine Neurotoxin -- Excitotoxins and Excitotoxicity -- Glutamate as a Neurotoxin -- Aspartate as a Neurotoxin -- Concept of Excitotoxicity via Glutamate Receptors -- Glutamate Neurotoxicity, Transport and Alternative Splicing of Transporters -- Excitotoxicity: A Complex Multistage Process Involving Different Mechanisms -- Glutamate Excitotoxicity Relation to Energy Failure -- Ionotropic Receptors in the Central Nervous System and Neurodegenerative Disorders -- Excitotoxicity and Axon Degeneration -- Glutamate Scavengers -- Quinolinate and Related Excitotoxins: Mechanisms of Neurotoxicity and Disease Relevanc -- Domoic Acid as a Neurotoxin -- BOAA and Neurotoxicit -- Endogenous Kynurenic Acid and Neurotoxicity -- Neuroprotection by Kynurenine Metabolites -- BMAA (beta-N-Methylamin -- Ionotropic Glutamate Receptors in Neurodegenerative and Other Disorders -- Okadaic acid modeling of Alzheimer's Disease -- Excitotoxicity in Parkinson's Disease -- Excitotoxicity and the Pathogenesis of Gliomas Excitotoxicity and Epielpsy; Epilepsy re Neurotoxicity Mechs -- Excitotoxicity in Multiple Sclerosis -- Excitotoxicity: Insights into Pathogenesis of AD -- Excitotoxicity and ALS: Insights into Pathogenesis -- Excitotoxicity and Amyotrophic Lateral Sclerosis -- Fungal Neurotoxins and ALS -- Excitotoxicity and Huntington Disease -- Excitotoxicity and Stroke -- Excitotoxicity in HIV Associated Neurocognitive Disordders -- Excitotoxicity and AIDS -- Excitotoxicity and Neuroprotection in Spinal Cord Injury -- Excitotoxicity in the Pathogenesis of Autism -- Cancer-Mediated Excitotoxicity., Excitotoxicity and Depression -- Lead and Excitotoxicity -- Glutamate and Neurodegeneration in the Retina -- Excitotoxicity and Epielpsy -- Seizures, Neurotrophin, Neuronal Death -- Neurodegenerative Aspets of Multiple System Atrophy -- Excitotoxicity in Ischemia and Reperfusion Injury -- Molecular, Cellular, and Behavioural Effects Produced by Perinatal Asphyxia: Neuroprotectants Targeting NMDA Receptor Signaling -- Neuroprotective Strategies in Amyotrophic Lateral Sclerosis Modulation of Neurotransmitory and Neurotrophic Input to Motor Neurons -- Neuroprotection in Demyelinating Diseases: The Therapeutic Potential of the Neurotrophins -- p75NTR: A Molecule with Multiple Functions in Amyloid-beta -- Metabolism and Neurotoxicity -- Neurotrophins and ALS -- Neurotrophic Factors & NeuroAIDS -- Neuroprotection by Poly (ADP-Ribose) Polymerase 1 (PARP-1) Inhibition -- Alzheimer's Disease and Neurotoxic Aspects -- Stem Cell Therapies for Age Associated Neurodegeneration -- Pathogenesis of Alzheimer's Disease -- Experimental Approach to Alzheimer Disease -- Potential Therapeutic Effects of Statins in Alzheimer's Disease -- Excitotoxicity and Alzheimer's Disease: Treatment Challenges -- Amyloid-beta, BDNF, and Mechanism of Neurodegeneration in Alzheimer's Diseases -- Drug Treatments: hopes, challenges -- Cannabinoids and Alzheimer's -- Heavy Metal Neurotoxicity -- Trimethyltin Neurotoxicity -- Mn Neurotoxicity -- MeHG -- Cd Neurotoxicity -- Fe Neurotoxicity -- Organoselenium -- Al Neurotoxicity -- Se Neurotoxicity -- Pb Neurotoxicity -- Cuprizone modelin of Multiple sclerosis.
Record Nr. UNINA-9910637715403321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
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Handbook of Stem Cell Applications [[electronic resource] /] / edited by Khawaja H. Haider
Handbook of Stem Cell Applications [[electronic resource] /] / edited by Khawaja H. Haider
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (167 illus., 47 illus. in color. eReference.)
Disciplina 571.6
616.02774
Soggetto topico Stem cells
Regenerative medicine
Nervous system - Diseases
Stem Cell Biology
Regenerative Medicine and Tissue Engineering
Neurological Disorders
ISBN 981-9971-19-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1_ The application of stem cells for the therapy of Parkinson’s disease -- Chapter 2_Stem cell therapy after neurological injuries -- Chapter 3_Strategies of Stem cell therapy in nervous system injuries repair and regeneration -- Chapter 4_Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders -- Chapter 5_Emerging Stem Cell Therapy and Tissue Engineering Approaches in Neurodegenerative Diseases -- Chapter 6_Next Generation of Science with Stem Cell-based Neural Organoids -- Chapter 7_Mesenchymal stem cells for ocular disorders -- Chapter 8_Keratocytes evolution in advanced regenerative corneal therapy with keratoconus -- Chapter 9_Latest advances in mesenchymal stem cell-based therapy of eye diseases -- Chapter 10_Stem cells in ophthalmology: from the bench to the bedside -- Chapter 11_Stem cells in periodontal regeneration -- Chapter 12_Dental pulp stem cells in Endodontics – Advances, applications and challenges -- Chapter 13_Significance of inflammatory milieu during regeneration of periodontal tissues using dental mesenchymal stem cell -- Chapter 14_3D bioprinting in conjunction with bone marrow mesenchymal stem cells for the treatment of bone defects -- Chapter 15_Allogenic Stem Cells: Advances in Knee Osteoarthritis -- Chapter 16_Mesenchymal stem cells for bone and cartilage regeneration: state-of-the-art -- Chapter 17_Clinical trials of cell therapy in muscular dystrophies -- Chapter 18_Scaling Stem Cells to Cure Millions of Patients with Diabetes – Approaches, Technology, and Future Directions -- Chapter 19_Restoring β-cells population through in situ differentiation of the resident pancreatic cells -- Chapter 20_Stem Cell-Based Regenerative Therapies for Functional Endocrine System Organs: Tissue Engineering Applications and Future Strategies -- Chapter 21_Recent advance in regenerativemedicine of the liver and bile duct system by chemically induced liver progenitor cells (CLiPs) -- Chapter 22_Advantages of a novel hepatic stem/progenitor cell population for fibrotic/cirrhotic liver repair and regeneration -- Chapter 23_ Evolving Understanding of Renal Progenitor (Stem) Cells in Renal Physiology and Pathophysiology -- Chapter 24_The regenerative potential of human adult renal stem/progenitor cells -- Chapter 25_Role of Exosomes as a biomarker in cardio-metabolic and renal diseases -- Chapter 26_Renovascular applications of stem cells -- Chapter 27_Reversing the aged Immune system with Stem cells -- Chapter 28_Germline stem cell technology in fertility preservation -- Chapter 29_One-stop shop for salivary gland regeneration and other exocrine organs -- Chapter 30_ Epithelial Stem Cell for Regeneration in Acute and Chronic Airway Injury -- Chapter 31_Genetic Cell Therapy in Anti-Aging Regenerative Cosmetology -- Chapter 32_Polytrauma and Stem Cells -- Chapter 33_The Multifaceted Role of Induced Pluripotent Stem Cells in Pre-Clinical Cardiac Regeneration Research -- Chapter 34_Stem cell-based regenerative medicine therapy in cancer -- Chapter 35_Novel Prognostic and Predictive Biomarkers in Oncology -- Chapter 36_Mesenchymal stem cells, cancer stem cells (CSCs), and circulating tumor cells (CTCs): roles and combinations in tumor growth and dissemination -- Chapter 37_ Participation of mesenchymal stem cell in the tumor process -- Chapter 38_Pre-enrichment of Adipose Tissue Grafts with Adipose Derived Stem Cells: Potential and Limitations -- Chapter 39_Matrix mechanical cues affect cell behavior and tissue regeneration -- Chapter 40_Biophysical regulators of mesenchymal stem cell fate -- Chapter 41_Influence of microbiota of donors and recipients in mesenchymal stem cell behavior regarding epigenetic pattern, stemness and secretome -- Chapter 42_Mesenchymal stem cells as modern off-the-shelf products: From research perspectives to clinical practice -- Chapter 43_Application of single-cell sequencing on stem cell research -- Chapter 44_Proteomics investigations on stem cell-based regenerative medicine -- Chapter 45_Phospholipid metabolism in stem cells and its application to pathological analysis -- Chapter 46_The role of stem cells in exercise enhanced organogenesis and regeneration -- Chapter 47_Mesenchymal stem cell-derived exosomes: A novel remedy for the treatment of Parkinson’s Disease -- Chapter 48_Time of cell injection -- Chapter 49_Novel Preconditioning approach to promote donor cell survival.
Record Nr. UNINA-9910845482403321
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Mechanisms and Emerging Therapies in Tremor Disorders [[electronic resource] /] / edited by Giuliana Grimaldi, Mario Manto
Mechanisms and Emerging Therapies in Tremor Disorders [[electronic resource] /] / edited by Giuliana Grimaldi, Mario Manto
Autore Grimaldi Giuliana
Edizione [2nd ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (556 pages)
Disciplina 616.8/3
Altri autori (Persone) MantoMario
Collana Contemporary Clinical Neuroscience
Soggetto topico Medicine - Research
Biology - Research
Neurology
Neurosciences
Nervous system - Diseases
Biomedical Research
Neuroscience
Neurological Disorders
ISBN 3-031-26128-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.
Record Nr. UNINA-9910754089503321
Grimaldi Giuliana  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Medical Neuroanatomy for the Boards and the Clinic [[electronic resource] ] : Finding the Lesion / / by Jonathan Leo
Medical Neuroanatomy for the Boards and the Clinic [[electronic resource] ] : Finding the Lesion / / by Jonathan Leo
Autore Leo Jonathan
Edizione [2nd ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (254 pages)
Disciplina 745.05
Soggetto topico Neurology
Neuroanatomy
Nervous system - Diseases
Neurosciences
Nervous system - Surgery
Neurological Disorders
Neuroscience
Neurosurgery
ISBN 3-031-41123-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface -- Chapter One: The Three Long Tracts and Spinal Cord Lesions -- Chapter Two: Corticobulbar Tract and Cranial Nerve Motor Nuclei.-Chapter Three: Abducens Nerve Lesions -- Chapter Four: Vestibulocochlear Nerve Lesions Historical Snippet: The Caloric Reflex Test, the Nobel Prize, and a POW -- Chapter Five: Visual Field Lesions Historical Snippet: Lesion Analysis of the Visual System -- Chapter Six: Autonomics and Lesions -- Chapter Seven: Facial Nerve Lesions -- Chapter Eight: Cerebellar Lesions -- Chapter Nine: Basal Ganglia Lesions -- Chapter Ten: Thalamus and Hypothalamus -- Chapter Eleven: Limbic System, Learning, Memory, and How the Brain Works Historical Snippet: Endothelial Derived Relaxing Factor = Nitric Oxide -- Chapter Twelve: Chemical Neuroanatomy Historical Snippet: The Opioid Epidemic in a Nutshell -- Chapter Thirteen: Brainstem Lesions -- Historical Snippet: Proustian Moment -- Chapter Fourteen: Cerebral Cortex Lesions Historical Snippet: London Cabbies and the Hippocampus -- Chapter Fifteen: Neurophysiology Historical Snippet: The Discovery of Acetylcholine and a Dream -- Chapter Sixteen: Neuroanatomy Atlas -- Chapter Seventeen: Lesion and Blood Vessel Test -- Chapter Eighteen: Key Words.-.
Record Nr. UNINA-9910754090503321
Leo Jonathan  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Music Therapy and Music-Based Interventions in Neurology [[electronic resource] ] : Perspectives on Research and Practice / / edited by Kerry Devlin, Kyurim Kang, Alexander Pantelyat
Music Therapy and Music-Based Interventions in Neurology [[electronic resource] ] : Perspectives on Research and Practice / / edited by Kerry Devlin, Kyurim Kang, Alexander Pantelyat
Autore Devlin Kerry
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Humana, , 2023
Descrizione fisica 1 online resource (239 pages)
Disciplina 615.85154
Altri autori (Persone) KangKyurim
PantelyatAlexander
Collana Current Clinical Neurology
Soggetto topico Neurology
Nervous system - Diseases
Neurological Disorders
ISBN 3-031-47092-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction: Principles and Overview of Music therapy and music-based intervention -- Mechanisms of Music Therapy and Music-Based Interventions -- Music for Stroke Rehabilitation -- Music for Traumatic Brain Injury and Impaired Consciousness -- Music for Movement Disorders -- Music for Speech Disorders -- Music for Memory Disorders -- Music for Neuro-Oncological Disorders -- Music Therapy and Music-Based Interventions for Neurologic Palliative Care -- Music for Autoimmune Neurological Disorders -- Music for Epilepsy -- Music for Surgical/Perioperative Care -- Telehealth Music Therapy in Adult Neurological Care -- Therapeutic Technology for Music-Based Interventions -- Music therapy and music-based approaches with autistic people: A Neurodiversity Paradigm-informed perspective -- Psychosocial Aspects of Music Therapy -- Conclusions and Future Directions.
Record Nr. UNINA-9910838289303321
Devlin Kerry  
Cham : , : Springer International Publishing : , : Imprint : Humana, , 2023
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