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Advanced Understanding of Neurodegenerative Diseases / / Raymond Chuen-Chung Chang, editor
| Advanced Understanding of Neurodegenerative Diseases / / Raymond Chuen-Chung Chang, editor |
| Pubbl/distr/stampa | Rijeka, Croatia : , : InTech, , [2011] |
| Descrizione fisica | 1 online resource (vii, 442 pages) : illustrations |
| Disciplina | 616.8 |
| Soggetto topico | Nervous system - Degeneration |
| ISBN | 953-51-6611-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910138278903321 |
| Rijeka, Croatia : , : InTech, , [2011] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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American journal of neurodegenerative disease
| American journal of neurodegenerative disease |
| Pubbl/distr/stampa | Madison, WI : , : E-Century Publishing Corporation, , [2012]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 573.8 |
| Soggetto topico |
Nervous system - Degeneration
Neuropathology Nerve Degeneration Nervous System |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Periodical |
| Soggetto non controllato | Neurology |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
Am. j. neurodegener dis
AJND |
| Record Nr. | UNINA-9910139734903321 |
| Madison, WI : , : E-Century Publishing Corporation, , [2012]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal models for neurodegenerative disease [[electronic resource] /] / edited by Jesús Avila, Jose J. Lucas and Félix Hernández
| Animal models for neurodegenerative disease [[electronic resource] /] / edited by Jesús Avila, Jose J. Lucas and Félix Hernández |
| Pubbl/distr/stampa | Cambridge [England], : RSC Pub., 2011 |
| Descrizione fisica | 1 online resource (307 p.) |
| Disciplina | 616.83 |
| Altri autori (Persone) |
AvilaJesús
LucasJosé J HernándezFélix |
| Collana | RSC drug discovery series |
| Soggetto topico |
Nervous system - Degeneration
Nervous system - Degeneration - Animal models |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-84973-275-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | i-iv; v-viii; ix-xvi; 1-14; 15-38; 39-51; 52-68; 69-85; 86-112; 113-161; 162-176; 177-213; 214-229; 230-250; 251-273; 274-283; 284-290 |
| Record Nr. | UNINA-9910461624503321 |
| Cambridge [England], : RSC Pub., 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal models for neurodegenerative disease [[electronic resource] /] / edited by Jesús Avila, Jose J. Lucas and Félix Hernández
| Animal models for neurodegenerative disease [[electronic resource] /] / edited by Jesús Avila, Jose J. Lucas and Félix Hernández |
| Pubbl/distr/stampa | Cambridge [England], : RSC Pub., 2011 |
| Descrizione fisica | 1 online resource (307 p.) |
| Disciplina | 616.83 |
| Altri autori (Persone) |
AvilaJesús
LucasJosé J HernándezFélix |
| Collana | RSC drug discovery series |
| Soggetto topico |
Nervous system - Degeneration
Nervous system - Degeneration - Animal models |
| ISBN | 1-84973-275-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | i-iv; v-viii; ix-xvi; 1-14; 15-38; 39-51; 52-68; 69-85; 86-112; 113-161; 162-176; 177-213; 214-229; 230-250; 251-273; 274-283; 284-290 |
| Record Nr. | UNINA-9910789402403321 |
| Cambridge [England], : RSC Pub., 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Autophagy and neurodegeneration / / David Rubinsztein
| Autophagy and neurodegeneration / / David Rubinsztein |
| Autore | Rubinsztein David (Cambridge Institute for Medical Research, UK) |
| Pubbl/distr/stampa | London, : Henry Stewart Talks, 2018 |
| Descrizione fisica | 1 online resource (1 streaming video file (39 min.) : color, sound) |
| Collana | Autophagy and lysosomal storage diseases |
| Soggetto topico |
Cell death
Lysosomes Nervous system - Degeneration Ataxin-3 Autophagy - physiology Lysosomes - metabolism Neurodegenerative Diseases - metabolism Neurodegenerative Diseases - pathology Neurodegenerative Diseases - therapy Signal Transduction - physiology |
| Formato | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents: Autophagy-lysosome pathway -- Autophagy signaling (canonical & non-canonical) -- Neurodegenerative diseases impairing autophagy -- Exploring pathogenic mechanism -- Ataxin 3 & autophagy -- Autophagy and neurodegeneration. |
| Record Nr. | UNINA-9910888489103321 |
Rubinsztein David (Cambridge Institute for Medical Research, UK)
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| London, : Henry Stewart Talks, 2018 | ||
| Videoregistrazioni | ||
| Lo trovi qui: Univ. Federico II | ||
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Biometals in neurodegenerative diseases : mechanisms and therapeutics / / edited by Anthony R. White [and three others]
| Biometals in neurodegenerative diseases : mechanisms and therapeutics / / edited by Anthony R. White [and three others] |
| Pubbl/distr/stampa | London, [England] : , : Academic Press, , 2017 |
| Descrizione fisica | 1 online resource (468 pages) |
| Disciplina | 612.3924 |
| Soggetto topico |
Metals in the body
Nervous system - Degeneration Metals - Physiological effect |
| ISBN | 0-12-804563-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Biometals and Alzheimer's disease / Alexandra I. Mot, Peter J. Crouch -- Copper in Alzheimer's disease / Rosanna Squitti, Maricarla Ventriglia, Mariacristina Siotto, Carlo Salustri -- The role of selenium in neurodegenerative diseases / Bárbara R. Cardoso, Dominic J. Hare, Ashley I. Bush -- Does HFE genotype impact macrophage phenotype in disease process and therapeutic response? / Anne M. Nixon, James R. Connor -- Chemical elements and oxidative status in neuroinflammation / Michela Ferraldeschi, Silvia Romano, Maria C. Buscarinu, Arianna Fornasiero, Rosella Mechelli, Benedetta Cerasoli, Anna Pino, Sonia Brescianini, Carlo Mattei, Maria A. Stazi, Alessandro Alimonti, Marco Salvetti, Giovanni Ristori -- Metals and neuroinflammation / Stephen C. Bondy -- Metals and prions / David R. Brown -- Manganese and neurodegeneration / Dinamene Marques Dos Santos, Michael Aschner, Ana P. Marrielha Dos Santos -- Zinc in autism / Stefanie Grabrucker, Andreas M. Grabrucker -- Metals and motor neuron disease / Per M. Roos -- Metals and Lysosomal storage disorders / Henna Kontinnen, Katarína Lejavová, Tarja Malm, Katja M Kanninen -- Developmental exposure to metals and its contribution to age-related neurodegeneration / Lucio G. Costa -- Metal biology associated with Huntington's disease / Terry Jo V. Bichell, Timothy C. Halbesma, K. Grace Tipps, Aaron B. Bowman -- Metal-binding to Amyloid-ss peptide / Melisa Del Barrio, Valentina Borghesani, Christelle Hureau, Peter Faller -- Metals and mitochondria in neurodegeneration / Germán Plascencia-Villa, Miguel José- Yacamán, George Perry -- Metal transporters in neurodegeneration / Hong Jiang -- Metal imaging in the brain / David C. Dorman -- Metalloregulation of protein clearance / Alejandra Ramírez Muñoz, Mark A. Greenough, Ashley I. Bush, Carlos M. Opazo -- Metals and autophagy in neurotoxicitiy / Peng Su, Michael Aschner, Jingyuan Chen, Wenjing Luo -- An overview of multifunctonal metal chelators as potential treatments for neurodegenerative diseases / Frank W. Lewis, David Tétard -- Abnormal function of metalloprotein underlies most neurodegenerative diseases / Katja M. Kanninen, Anthony R. White. |
| Record Nr. | UNINA-9910583469903321 |
| London, [England] : , : Academic Press, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical modulators of protein misfolding and neurodegenerative disease / / Pierfausto Seneci
| Chemical modulators of protein misfolding and neurodegenerative disease / / Pierfausto Seneci |
| Autore | Seneci Pierfausto |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (260 p.) |
| Disciplina | 616.8047 |
| Altri autori (Persone) | SeneciPierfausto <1960-> |
| Soggetto topico | Nervous system - Degeneration |
| ISBN | 0-12-801959-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright Page; Dedication; Contents; Abbreviations; Chapter 1 - Chemical Modulators of Protein Misfolding, Neurodegeneration and Tau; 1.1 - Tau-targeted compounds; 1.1.1 - Tau Kinase Inhibitors; 1.1.2 - Tau O-GlcNAcylation Enhancers; 1.1.3 - Microtubule (MT)-binding Compounds; 1.2 - Ab-targeted compounds; 1.2.1 - γ-Secretase Inhibitors (GSIs) and Modulators (GSMs); 1.2.2 - Multi-targeted Neuroprotective and Proneurogenic Compounds; References; Chapter 2 - Targeting the Protein Quality Control (PQC) Machinery; 2.1 - Molecular chaperones, pqc, and neurodegeneration
2.2 - Hsp272.3 - Hsp70; 2.3.1 - Hsp70 Inhibitors; 2.3.2 - Hsp70-BAG-1 Inhibitors; 2.4 - Hsp90; 2.4.1 - Hsp90 Inhibitors; 2.4.2 - Hsp90-Co-chaperone Complexes: Direct Inhibition; 2.4.3 - Hsp90-Co-chaperone Complexes: Indirect Inhibition; 2.5 - Recap; References; Chapter 3 - Targeting Proteasomal Degradation of Soluble, Misfolded Proteins; 3.1 - UPS-mediated degradation of misfolded proteins; 3.2 - CHIP; 3.3 - USP14; 3.4 - Recap; References; Chapter 4 - Targeting Unselective Autophagy of Cellular Aggregates; 4.1 - Macroautophagy mediated degradation of protein aggregates; 4.2 - mTORC1 4.3 - Small molecule enhancers of rapamycin (sMERs)4.4 - Recap; References; Chapter 5 - Targeting Selective Autophagy of Insoluble Protein Aggregates; 5.1 - Aggrephagy-mediated degradation of protein aggregates; 5.2 - p62; 5.3 - HDAC6; 5.4 - Recap; References; Chapter 6 - Targeting Assembly and Disassembly of Protein Aggregates; 6.1 - Disordered protein aggregates and ordered amyloid fibrils; 6.2 - Interfering with (neuro)toxic tau species in the aggregation process; 6.3 - Hsp110-driven disaggregation; 6.4 - Recap; References; Index |
| Record Nr. | UNINA-9910787447203321 |
|
Seneci Pierfausto
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| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical modulators of protein misfolding and neurodegenerative disease / / Pierfausto Seneci
| Chemical modulators of protein misfolding and neurodegenerative disease / / Pierfausto Seneci |
| Autore | Seneci Pierfausto |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2015 |
| Descrizione fisica | 1 online resource (260 p.) |
| Disciplina | 616.8047 |
| Altri autori (Persone) | SeneciPierfausto <1960-> |
| Soggetto topico | Nervous system - Degeneration |
| ISBN | 0-12-801959-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Title Page; Copyright Page; Dedication; Contents; Abbreviations; Chapter 1 - Chemical Modulators of Protein Misfolding, Neurodegeneration and Tau; 1.1 - Tau-targeted compounds; 1.1.1 - Tau Kinase Inhibitors; 1.1.2 - Tau O-GlcNAcylation Enhancers; 1.1.3 - Microtubule (MT)-binding Compounds; 1.2 - Ab-targeted compounds; 1.2.1 - γ-Secretase Inhibitors (GSIs) and Modulators (GSMs); 1.2.2 - Multi-targeted Neuroprotective and Proneurogenic Compounds; References; Chapter 2 - Targeting the Protein Quality Control (PQC) Machinery; 2.1 - Molecular chaperones, pqc, and neurodegeneration
2.2 - Hsp272.3 - Hsp70; 2.3.1 - Hsp70 Inhibitors; 2.3.2 - Hsp70-BAG-1 Inhibitors; 2.4 - Hsp90; 2.4.1 - Hsp90 Inhibitors; 2.4.2 - Hsp90-Co-chaperone Complexes: Direct Inhibition; 2.4.3 - Hsp90-Co-chaperone Complexes: Indirect Inhibition; 2.5 - Recap; References; Chapter 3 - Targeting Proteasomal Degradation of Soluble, Misfolded Proteins; 3.1 - UPS-mediated degradation of misfolded proteins; 3.2 - CHIP; 3.3 - USP14; 3.4 - Recap; References; Chapter 4 - Targeting Unselective Autophagy of Cellular Aggregates; 4.1 - Macroautophagy mediated degradation of protein aggregates; 4.2 - mTORC1 4.3 - Small molecule enhancers of rapamycin (sMERs)4.4 - Recap; References; Chapter 5 - Targeting Selective Autophagy of Insoluble Protein Aggregates; 5.1 - Aggrephagy-mediated degradation of protein aggregates; 5.2 - p62; 5.3 - HDAC6; 5.4 - Recap; References; Chapter 6 - Targeting Assembly and Disassembly of Protein Aggregates; 6.1 - Disordered protein aggregates and ordered amyloid fibrils; 6.2 - Interfering with (neuro)toxic tau species in the aggregation process; 6.3 - Hsp110-driven disaggregation; 6.4 - Recap; References; Index |
| Record Nr. | UNINA-9910807756203321 |
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Seneci Pierfausto
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| London, England : , : Academic Press, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Degenerative neurological and neuromuscular disease
| Degenerative neurological and neuromuscular disease |
| Pubbl/distr/stampa | [Auckland, N.Z.], : Dove Medical Press |
| Soggetto topico |
Nervous system - Degeneration
Neuromuscular diseases Neurology Neuromuscular Diseases Neurodegenerative Diseases |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Periodical |
| Soggetto non controllato | Neurology |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996336264303316 |
| [Auckland, N.Z.], : Dove Medical Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Degenerative neurological and neuromuscular disease
| Degenerative neurological and neuromuscular disease |
| Pubbl/distr/stampa | [Auckland, N.Z.], : Dove Medical Press |
| Soggetto topico |
Nervous system - Degeneration
Neuromuscular diseases Neurodegenerative Diseases Neuromuscular Diseases Maladies neuromusculaires Neurology |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910140401103321 |
| [Auckland, N.Z.], : Dove Medical Press | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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