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Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor
| Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2008 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) | BoggsJoan M |
| Collana | Intrinsically disordered proteins |
| Soggetto topico |
Myelin basic protein
Myelin sheath |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60876-247-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""MYELIN BASIC PROTEIN""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""REFERENCES""; ""THE PROPERTIES AND FUNCTIONS OF THE GOLLI MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""The MBP gene encodes the “classic� and golli family of proteins""; ""Features of the primary and higher ordered structure of the golli-MBPs""; ""Approaches to defining the biological roles of golli proteins in cells""; ""Unique phenotypes of the golli KO and golli overexpressing mice""; ""Emerging relevance of golli expression in pathology and disease""; ""CONCLUSION""; ""ACKNOWLEDGEMENTS""
""REFERENCES""""POSTTRANSLATIONAL MODIFICATIONS OF MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""ACETYLATION""; ""METHYLATION""; ""PHOSPHORYLATION""; ""Deamidation of glutamine at residues 103 and 147""; ""Deimination of arginine residues (citrullination)""; ""CONCLUSION""; ""REFERENCES""; ""DEIMINATION OF MYELIN BASIC PROTEIN BY PAD ENZYMES, AND THEIR ROLE IN MULTIPLE SCLEROSIS""; ""ABSTRACT""; ""INTRODUCTION""; ""MBP CHARGE ISOMERS""; ""CONSEQUENCES OF INCREASED CITRULLINATION OF MBP""; ""A. Proteolysis""; ""B. MBP autocatalysis and neoepitopes"" ""THE ROLE OF MYELIN BASIC PROTEIN IN MYELIN COMPACTION""""BILAYER STRUCTURE IN NORMAL APPEARING WHITE MATTER (NAWM) IN MS BRAIN IS NOT “NORMAL�""; ""MBP MICROHETEROGENEITY IN MS WHITE MATTER""; ""PEPTIDYL ARGININE DEIMINASES (PADS)""; ""THE PAD2 CPG ISLAND""; ""FUTURE DIRECTIONS AND CONCLUDING REMARKS""; ""ACKNOWLEDGEMENTS""; ""REFERENCES""; ""MYELIN BASIC PROTEIN-MEDIATED IMMUNOPATHOGENESIS IN MULTIPLE SCLEROSIS AND EAE""; ""ABSTRACT""; ""INTRODUCTION""; ""EXPRESSION OF MBP IN THE CNS AND THE IMMUNE SYSTEM""; ""MULTIPLE SCLEROSIS AND EAE"" ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN MS""""FREQUENCY AND PHENOTYPES OF CD4+ T CELLS IN MS PATIENTS""; ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN EAE""; ""EAE AND MS: TH1 VS. TH17?""; ""MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""HUMANIZED MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""MBP-SPECIFIC CD8+ T CELLS INVOLVED IN MS""; ""PATHOGENICITY OF MBP-SPECIFIC CD8+ T CELLS IS DEMONSTRATED IN NEW EAE MODELS""; ""B CELLS INVOLVED IN MS AND EAE""; ""IMMUNE TOLERANCE TO SELF-ANTIGENS""; ""CD4+ T CELL IMMUNE TOLERANCE TO MBP""; ""CD8+ T CELL IMMUNE TOLERANCE TO MBP""; ""CONCLUSION"" ""REFERENCES""""A STRUCTURAL PERSPECTIVE OF PEPTIDES FROM MYELIN BASIC PROTEIN""; ""ABSTRACT""; ""ABBREVIATIONS""; ""INTRODUCTION""; ""CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101, DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN MBP85-99""; ""Peptide interactions with HLA-DR2A""; ""Peptide interactions with Ob.1A.12 TCR""; ""STRUCTURE OF HUMAN MHC CLASS II COMPLEXED WITH A LONGER EPITOPE PEPTIDE (MBP86-105) FROM HUMAN MYELIN BASIC PROTEIN""; ""Interactions with HLA-DR2a / 2b""; ""Interactions with TCR"" ""Structure of a human TCR complexed with a peptide from human MBP89-101 and a MHC class II molecule"" |
| Record Nr. | UNINA-9910455361503321 |
| New York, : Nova Science Publishers, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor
| Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2008 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) | BoggsJoan M |
| Collana | Intrinsically disordered proteins |
| Soggetto topico |
Myelin basic protein
Myelin sheath |
| ISBN | 1-60876-247-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""MYELIN BASIC PROTEIN""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""REFERENCES""; ""THE PROPERTIES AND FUNCTIONS OF THE GOLLI MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""The MBP gene encodes the “classic� and golli family of proteins""; ""Features of the primary and higher ordered structure of the golli-MBPs""; ""Approaches to defining the biological roles of golli proteins in cells""; ""Unique phenotypes of the golli KO and golli overexpressing mice""; ""Emerging relevance of golli expression in pathology and disease""; ""CONCLUSION""; ""ACKNOWLEDGEMENTS""
""REFERENCES""""POSTTRANSLATIONAL MODIFICATIONS OF MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""ACETYLATION""; ""METHYLATION""; ""PHOSPHORYLATION""; ""Deamidation of glutamine at residues 103 and 147""; ""Deimination of arginine residues (citrullination)""; ""CONCLUSION""; ""REFERENCES""; ""DEIMINATION OF MYELIN BASIC PROTEIN BY PAD ENZYMES, AND THEIR ROLE IN MULTIPLE SCLEROSIS""; ""ABSTRACT""; ""INTRODUCTION""; ""MBP CHARGE ISOMERS""; ""CONSEQUENCES OF INCREASED CITRULLINATION OF MBP""; ""A. Proteolysis""; ""B. MBP autocatalysis and neoepitopes"" ""THE ROLE OF MYELIN BASIC PROTEIN IN MYELIN COMPACTION""""BILAYER STRUCTURE IN NORMAL APPEARING WHITE MATTER (NAWM) IN MS BRAIN IS NOT “NORMAL�""; ""MBP MICROHETEROGENEITY IN MS WHITE MATTER""; ""PEPTIDYL ARGININE DEIMINASES (PADS)""; ""THE PAD2 CPG ISLAND""; ""FUTURE DIRECTIONS AND CONCLUDING REMARKS""; ""ACKNOWLEDGEMENTS""; ""REFERENCES""; ""MYELIN BASIC PROTEIN-MEDIATED IMMUNOPATHOGENESIS IN MULTIPLE SCLEROSIS AND EAE""; ""ABSTRACT""; ""INTRODUCTION""; ""EXPRESSION OF MBP IN THE CNS AND THE IMMUNE SYSTEM""; ""MULTIPLE SCLEROSIS AND EAE"" ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN MS""""FREQUENCY AND PHENOTYPES OF CD4+ T CELLS IN MS PATIENTS""; ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN EAE""; ""EAE AND MS: TH1 VS. TH17?""; ""MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""HUMANIZED MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""MBP-SPECIFIC CD8+ T CELLS INVOLVED IN MS""; ""PATHOGENICITY OF MBP-SPECIFIC CD8+ T CELLS IS DEMONSTRATED IN NEW EAE MODELS""; ""B CELLS INVOLVED IN MS AND EAE""; ""IMMUNE TOLERANCE TO SELF-ANTIGENS""; ""CD4+ T CELL IMMUNE TOLERANCE TO MBP""; ""CD8+ T CELL IMMUNE TOLERANCE TO MBP""; ""CONCLUSION"" ""REFERENCES""""A STRUCTURAL PERSPECTIVE OF PEPTIDES FROM MYELIN BASIC PROTEIN""; ""ABSTRACT""; ""ABBREVIATIONS""; ""INTRODUCTION""; ""CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101, DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN MBP85-99""; ""Peptide interactions with HLA-DR2A""; ""Peptide interactions with Ob.1A.12 TCR""; ""STRUCTURE OF HUMAN MHC CLASS II COMPLEXED WITH A LONGER EPITOPE PEPTIDE (MBP86-105) FROM HUMAN MYELIN BASIC PROTEIN""; ""Interactions with HLA-DR2a / 2b""; ""Interactions with TCR"" ""Structure of a human TCR complexed with a peptide from human MBP89-101 and a MHC class II molecule"" |
| Record Nr. | UNINA-9910778008503321 |
| New York, : Nova Science Publishers, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor
| Myelin basic protein [[electronic resource] /] / Joan M. Boggs, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2008 |
| Descrizione fisica | 1 online resource (261 p.) |
| Disciplina | 572/.633 |
| Altri autori (Persone) | BoggsJoan M |
| Collana | Intrinsically disordered proteins |
| Soggetto topico |
Myelin basic protein
Myelin sheath |
| ISBN | 1-60876-247-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""MYELIN BASIC PROTEIN""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""REFERENCES""; ""THE PROPERTIES AND FUNCTIONS OF THE GOLLI MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""The MBP gene encodes the “classic� and golli family of proteins""; ""Features of the primary and higher ordered structure of the golli-MBPs""; ""Approaches to defining the biological roles of golli proteins in cells""; ""Unique phenotypes of the golli KO and golli overexpressing mice""; ""Emerging relevance of golli expression in pathology and disease""; ""CONCLUSION""; ""ACKNOWLEDGEMENTS""
""REFERENCES""""POSTTRANSLATIONAL MODIFICATIONS OF MYELIN BASIC PROTEINS""; ""ABSTRACT""; ""INTRODUCTION""; ""ACETYLATION""; ""METHYLATION""; ""PHOSPHORYLATION""; ""Deamidation of glutamine at residues 103 and 147""; ""Deimination of arginine residues (citrullination)""; ""CONCLUSION""; ""REFERENCES""; ""DEIMINATION OF MYELIN BASIC PROTEIN BY PAD ENZYMES, AND THEIR ROLE IN MULTIPLE SCLEROSIS""; ""ABSTRACT""; ""INTRODUCTION""; ""MBP CHARGE ISOMERS""; ""CONSEQUENCES OF INCREASED CITRULLINATION OF MBP""; ""A. Proteolysis""; ""B. MBP autocatalysis and neoepitopes"" ""THE ROLE OF MYELIN BASIC PROTEIN IN MYELIN COMPACTION""""BILAYER STRUCTURE IN NORMAL APPEARING WHITE MATTER (NAWM) IN MS BRAIN IS NOT “NORMAL�""; ""MBP MICROHETEROGENEITY IN MS WHITE MATTER""; ""PEPTIDYL ARGININE DEIMINASES (PADS)""; ""THE PAD2 CPG ISLAND""; ""FUTURE DIRECTIONS AND CONCLUDING REMARKS""; ""ACKNOWLEDGEMENTS""; ""REFERENCES""; ""MYELIN BASIC PROTEIN-MEDIATED IMMUNOPATHOGENESIS IN MULTIPLE SCLEROSIS AND EAE""; ""ABSTRACT""; ""INTRODUCTION""; ""EXPRESSION OF MBP IN THE CNS AND THE IMMUNE SYSTEM""; ""MULTIPLE SCLEROSIS AND EAE"" ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN MS""""FREQUENCY AND PHENOTYPES OF CD4+ T CELLS IN MS PATIENTS""; ""MBP PEPTIDE SPECIFICITY OF CD4+ T CELLS IN EAE""; ""EAE AND MS: TH1 VS. TH17?""; ""MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""HUMANIZED MBP-SPECIFIC CD4+ TCR TRANSGENIC MICE""; ""MBP-SPECIFIC CD8+ T CELLS INVOLVED IN MS""; ""PATHOGENICITY OF MBP-SPECIFIC CD8+ T CELLS IS DEMONSTRATED IN NEW EAE MODELS""; ""B CELLS INVOLVED IN MS AND EAE""; ""IMMUNE TOLERANCE TO SELF-ANTIGENS""; ""CD4+ T CELL IMMUNE TOLERANCE TO MBP""; ""CD8+ T CELL IMMUNE TOLERANCE TO MBP""; ""CONCLUSION"" ""REFERENCES""""A STRUCTURAL PERSPECTIVE OF PEPTIDES FROM MYELIN BASIC PROTEIN""; ""ABSTRACT""; ""ABBREVIATIONS""; ""INTRODUCTION""; ""CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101, DRB1*1501) COMPLEXED WITH A PEPTIDE FROM HUMAN MYELIN BASIC PROTEIN MBP85-99""; ""Peptide interactions with HLA-DR2A""; ""Peptide interactions with Ob.1A.12 TCR""; ""STRUCTURE OF HUMAN MHC CLASS II COMPLEXED WITH A LONGER EPITOPE PEPTIDE (MBP86-105) FROM HUMAN MYELIN BASIC PROTEIN""; ""Interactions with HLA-DR2a / 2b""; ""Interactions with TCR"" ""Structure of a human TCR complexed with a peptide from human MBP89-101 and a MHC class II molecule"" |
| Record Nr. | UNINA-9910819670703321 |
| New York, : Nova Science Publishers, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Myelin repair and neuroprotection in multiple sclerosis / / Ian D. Duncan, Robin J.M. Franklin, editors
| Myelin repair and neuroprotection in multiple sclerosis / / Ian D. Duncan, Robin J.M. Franklin, editors |
| Pubbl/distr/stampa | New York, : Springer, 2012, c2013 |
| Descrizione fisica | 1 online resource (295 p.) |
| Disciplina |
616.8
616.83407 |
| Altri autori (Persone) |
DuncanIan D
FranklinRobin J. M |
| Soggetto topico |
Myelin sheath
Multiple sclerosis - Patients - Rehabilitation |
| ISBN |
1-283-61317-4
9786613925626 1-4614-2218-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Development of oligodendrocytes in the vertebrate CNS -- Demyelination and remyelination in multiple sclerosis -- Microglia function in MS pathology -- Endogenous remyelination in the CNS -- Exogenous cell myelin repair and neuroprotection in multiple sclerosis -- A peripheral alternative to central nervous system myelin repair -- Immune modulation and repair following neural stem transplantation -- Axonal protection with sodium channel blocking agents in models of multiple sclerosis -- Effects of current medical therapies on reparative and neuroprotective functions in multiple sclerosis -- Imaging of demyelination and remyelination in multiple sclerosis -- Designing clinical trials to test neuroprotective therapies in multiple sclerosis. |
| Record Nr. | UNINA-9910437618903321 |
| New York, : Springer, 2012, c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
