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Fungal infection [[electronic resource] ] : diagnosis and management / / Malcolm D. Richardson, David W. Warnock
| Fungal infection [[electronic resource] ] : diagnosis and management / / Malcolm D. Richardson, David W. Warnock |
| Autore | Richardson M. D |
| Edizione | [4th ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, U.K., : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (477 p.) |
| Disciplina | 616.9/69 |
| Altri autori (Persone) | WarnockD. W |
| Soggetto topico |
Mycoses - Diagnosis
Mycoses - Treatment |
| ISBN |
1-283-40610-1
9786613406101 1-118-32149-9 1-4443-6099-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910141151903321 |
Richardson M. D
|
||
| Chichester, West Sussex, U.K., : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fungal infection : diagnosis and management / / Malcolm D. Richardson, David W. Warnock
| Fungal infection : diagnosis and management / / Malcolm D. Richardson, David W. Warnock |
| Autore | Richardson M. D |
| Edizione | [4th ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, U.K., : Wiley-Blackwell, 2012 |
| Descrizione fisica | 1 online resource (477 p.) |
| Disciplina | 616.9/69 |
| Altri autori (Persone) | WarnockD. W |
| Soggetto topico |
Mycoses - Diagnosis
Mycoses - Treatment |
| ISBN |
1-283-40610-1
9786613406101 1-118-32149-9 1-4443-6099-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Fungal Infection : DIAGNOSIS AND MANAGEMENT -- Contents -- Preface to the fourth edition -- Preface to the first edition -- Acknowledgements -- 1 Introduction -- 1.1 The nature of fungi -- 1.2 Classification and nomenclature of fungi and fungal diseases -- 1.3 Fungi as human pathogens -- 1.3.1 The superficial mycoses -- 1.3.2 The subcutaneous mycoses -- 1.3.3 The systemic mycoses -- 1.4 The changing pattern of fungal infection -- 1.5 New directions in diagnosis -- 1.6 New directions in treatment and prevention -- Further reading -- 2 Laboratory diagnosis of fungal infection -- 2.1 Introduction -- 2.2 Collection of specimens -- 2.2.1 Skin, nails and hair -- 2.2.2 Mucous membranes -- 2.2.3 Ear -- 2.2.4 Eye -- 2.2.5 Blood -- 2.2.6 Cerebrospinal fluid -- 2.2.7 Urine -- 2.2.8 Other fluids -- 2.2.9 Lower respiratory tract specimens -- 2.2.10 Pus -- 2.2.11 Bone marrow -- 2.2.12 Tissue -- 2.2.13 Medical devices -- 2.3 Specimens for serological tests -- 2.4 Specimens for antifungal drug level determinations -- 2.5 Transport of specimens -- 2.6 Interpretation of laboratory test results -- 2.6.1 Direct microscopic examination -- 2.6.2 Histopathological examination -- 2.6.3 Immunohistochemistry -- 2.6.4 In situ hybridization -- 2.6.5 Culture -- 2.6.6 Fungal identification -- 2.6.7 Molecular identification -- 2.6.8 Serological tests -- 2.6.9 β-D-glucan detection -- 2.7 Molecular diagnosis of fungal infection -- Further reading -- 3 Antifungal drugs -- 3.1 Introduction -- 3.2 Allylamines -- 3.2.1 Mechanism of action -- 3.3 Terbinafine -- 3.3.1 Spectrum of activity -- 3.3.2 Acquired resistance -- 3.3.3 Pharmacokinetics -- 3.3.4 Pharmaceutics -- 3.3.5 Therapeutic use -- 3.3.6 Mode of administration -- 3.3.7 Drug interactions -- 3.3.8 Toxicity and adverse reactions -- 3.4 Other allylamine compounds for topical administration -- 3.4.1 Naftifine.
3.5 Azoles -- 3.5.1 Mechanism of action -- 3.5.2 Acquired resistance -- 3.5.3 Drug interactions -- 3.6 Fluconazole -- 3.6.1 Spectrum of activity -- 3.6.2 Acquired resistance -- 3.6.3 Pharmacokinetics -- 3.6.4 Pharmaceutics -- 3.6.5 Therapeutic use -- 3.6.6 Mode of administration -- 3.6.7 Drug interactions -- 3.6.8 Toxicity and adverse reactions -- 3.7 Itraconazole -- 3.7.1 Spectrum of activity -- 3.7.2 Acquired resistance -- 3.7.3 Pharmacokinetics -- 3.7.4 Pharmaceutics -- 3.7.5 Therapeutic use -- 3.7.6 Mode of administration -- 3.7.7 Drug interactions -- 3.7.8 Toxicity and adverse reactions -- 3.8 Ketoconazole -- 3.8.1 Spectrum of activity -- 3.8.2 Acquired resistance -- 3.8.3 Pharmacokinetics -- 3.8.4 Pharmaceutics -- 3.8.5 Therapeutic use -- 3.8.6 Mode of administration -- 3.8.7 Drug interactions -- 3.8.8 Toxicity and adverse reactions -- 3.9 Posaconazole -- 3.9.1 Spectrum of activity -- 3.9.2 Acquired resistance -- 3.9.3 Pharmacokinetics -- 3.9.4 Pharmaceutics -- 3.9.5 Therapeutic use -- 3.9.6 Mode of administration -- 3.9.7 Drug interactions -- 3.9.8 Toxicity and adverse reactions -- 3.10 Voriconazole -- 3.10.1 Spectrum of activity -- 3.10.2 Acquired resistance -- 3.10.3 Pharmacokinetics -- 3.10.4 Pharmaceutics -- 3.10.5 Therapeutic use -- 3.10.6 Mode of administration -- 3.10.7 Drug interactions -- 3.10.8 Toxicity and adverse reactions -- 3.11 Other imidazole compounds for topical administration -- 3.11.1 Bifonazole -- 3.11.2 Butoconazole -- 3.11.3 Clotrimazole -- 3.11.4 Econazole nitrate -- 3.11.5 Fenticonazole nitrate -- 3.11.6 Isoconazole nitrate -- 3.11.7 Miconazole nitrate -- 3.11.8 Oxiconazole -- 3.11.9 Sertaconazole nitrate -- 3.11.10 Sulconazole nitrate -- 3.11.11 Terconazole -- 3.11.12 Tioconazole -- 3.12 Echinocandins -- 3.12.1 Mechanism of action -- 3.12.2 Spectrum of activity -- 3.12.3 Acquired resistance -- 3.12.4 Drug interactions. 3.13 Anidulafungin -- 3.13.1 Pharmacokinetics -- 3.13.2 Pharmaceutics -- 3.13.3 Therapeutic use -- 3.13.4 Mode of administration -- 3.13.5 Drug interactions -- 3.13.6 Toxicity and adverse reactions -- 3.14 Caspofungin -- 3.14.1 Pharmacokinetics -- 3.14.2 Pharmaceutics -- 3.14.3 Therapeutic use -- 3.14.4 Mode of administration -- 3.14.5 Drug interactions -- 3.14.6 Toxicity and adverse reactions -- 3.15 Micafungin -- 3.15.1 Pharmacokinetics -- 3.15.2 Pharmaceutics -- 3.15.3 Therapeutic use -- 3.15.4 Mode of administration -- 3.15.5 Drug interactions -- 3.15.6 Toxicity and adverse reactions -- 3.16 Polyenes -- 3.16.1 Mechanism of action -- 3.17 Amphotericin B -- 3.17.1 Spectrum of activity -- 3.17.2 Acquired resistance -- 3.17.3 Pharmacokinetics -- 3.17.4 Pharmaceutics -- 3.17.5 Therapeutic use -- 3.17.6 Mode of administration -- 3.17.7 Drug interactions -- 3.17.8 Toxicity and adverse reactions -- 3.18 Other polyene compounds for topical administration -- 3.18.1 Natamycin -- 3.18.2 Nystatin -- 3.19 Flucytosine -- 3.19.1 Mechanism of action -- 3.19.2 Spectrum of activity -- 3.19.3 Acquired resistance -- 3.19.4 Pharmacokinetics -- 3.19.5 Pharmaceutics -- 3.19.6 Therapeutic use -- 3.19.7 Mode of administration -- 3.19.8 Drug interactions -- 3.19.9 Toxicity and adverse reactions -- 3.20 Griseofulvin -- 3.20.1 Mechanism of action -- 3.20.2 Spectrum of activity -- 3.20.3 Acquired resistance -- 3.20.4 Pharmacokinetics -- 3.20.5 Pharmaceutics -- 3.20.6 Therapeutic use -- 3.20.7 Mode of administration -- 3.20.8 Drug interactions -- 3.20.9 Toxicity and adverse reactions -- 3.21 Other miscellaneous compounds for topical administration -- 3.21.1 Amorolfine hydrochloride -- 3.21.2 Butenafine hydrochloride -- 3.21.3 Ciclopiroxolamine -- 3.21.4 Haloprogin -- 3.21.5 Tolnaftate -- 3.22 Prophylactic treatment for prevention of fungal infection. 3.23 Empirical treatment of suspected fungal infection in the neutropenic patient -- 3.24 Pre-emptive antifungal treatment -- 3.25 Combination antifungal treatment of invasive fungal infections -- 3.26 Laboratory monitoring -- 3.26.1 Antifungal drug susceptibility testing -- 3.26.2 Monitoring of blood concentrations of antifungal drugs -- Further reading -- 4 Dermatophytosis -- 4.1 Introduction -- 4.2 The causal organisms and their habitat -- 4.3 Epidemiology -- 4.4 Laboratory diagnosis of dermatophytosis -- 4.5 Tinea capitis -- 4.5.1 Definition -- 4.5.2 Geographical distribution -- 4.5.3 Causal organisms -- 4.5.4 Epidemiology -- 4.5.5 Clinical manifestations -- 4.5.6 Differential diagnosis -- 4.5.7 Essential investigations and their interpretation -- 4.5.8 Management -- 4.5.9 Prevention -- 4.6 Tinea corporis -- 4.6.1 Definition -- 4.6.2 Geographical distribution -- 4.6.3 Causal organisms -- 4.6.4 Epidemiology -- 4.6.5 Clinical manifestations -- 4.6.6 Differential diagnosis -- 4.6.7 Essential investigations and their interpretation -- 4.6.8 Management -- 4.6.9 Prevention -- 4.7 Tinea cruris -- 4.7.1 Definition -- 4.7.2 Geographical distribution -- 4.7.3 Causal organisms -- 4.7.4 Epidemiology -- 4.7.5 Clinical manifestations -- 4.7.6 Differential diagnosis -- 4.7.7 Essential investigations and their interpretation -- 4.7.8 Management -- 4.7.9 Prevention -- 4.8 Tinea pedis -- 4.8.1 Definition -- 4.8.2 Geographical distribution -- 4.8.3 Causal organisms -- 4.8.4 Epidemiology -- 4.8.5 Clinical manifestations -- 4.8.6 Differential diagnosis -- 4.8.7 Essential investigations and their interpretation -- 4.8.8 Management -- 4.8.9 Prevention -- 4.9 Tinea manuum -- 4.9.1 Definition -- 4.9.2 Geographical distribution -- 4.9.3 Causal organisms -- 4.9.4 Epidemiology -- 4.9.5 Clinical manifestations -- 4.9.6 Differential diagnosis. 4.9.7 Essential investigations and their interpretation -- 4.9.8 Management -- 4.9.9 Prevention -- 4.10 Tinea unguium -- 4.10.1 Definition -- 4.10.2 Geographical distribution -- 4.10.3 Causal organisms -- 4.10.4 Epidemiology -- 4.10.5 Clinical manifestations -- 4.10.6 Differential diagnosis -- 4.10.7 Essential investigations and their interpretation -- 4.10.8 Management -- 4.10.9 Prevention -- Further reading -- 5 Superficial candidosis -- 5.1 Definition -- 5.2 Geographical distribution -- 5.3 The causal organisms and their habitat -- 5.4 Epidemiology -- 5.5 Clinical manifestations -- 5.5.1 Oropharyngeal candidosis -- 5.5.2 Vaginal candidosis -- 5.5.3 Penile candidosis -- 5.5.4 Cutaneous candidosis -- 5.5.5 Candida nail infection -- 5.5.6 Chronic mucocutaneous candidosis -- 5.6 Essential investigations and their interpretation -- 5.7 Management -- 5.7.1 Oropharyngeal candidosis -- 5.7.2 Vaginal candidosis -- 5.7.3 Penile candidosis -- 5.7.4 Cutaneous candidosis -- 5.7.5 Candida nail infection -- 5.7.6 Chronic mucocutaneous candidosis -- 5.8 Prevention -- Further reading -- 6 Other cutaneous fungal infections -- 6.1 Pityriasis versicolor -- 6.1.1 Definition -- 6.1.2 Geographical distribution -- 6.1.3 The causal organisms and their habitat -- 6.1.4 Epidemiology -- 6.1.5 Clinical manifestations -- 6.1.6 Differential diagnosis -- 6.1.7 Essential investigations and their interpretation -- 6.1.8 Management -- 6.2 Other Malassezia infections -- 6.2.1 Malassezia folliculitis -- 6.2.2 Seborrhoeic dermatitis -- 6.3 Piedra -- 6.4 White piedra -- 6.4.1 Definition -- 6.4.2 Geographical distribution -- 6.4.3 The causal organisms and their habitat -- 6.4.4 Epidemiology -- 6.4.5 Clinical manifestations -- 6.4.6 Differential diagnosis -- 6.4.7 Essential investigations and their interpretation -- 6.4.8 Management -- 6.5 Black piedra -- 6.5.1 Definition. 6.5.2 Geographical distribution. |
| Record Nr. | UNINA-9910815905603321 |
|
Richardson M. D
|
||
| Chichester, West Sussex, U.K., : Wiley-Blackwell, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro
| Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2020] |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 616.969 |
| Collana | Pocket guides to biomedical sciences |
| Soggetto topico |
Medical mycology
Mycoses - Diagnosis |
| ISBN |
1-351-67766-7
1-351-67767-5 1-315-16562-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910793837503321 |
| Boca Raton : , : CRC Press, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro
| Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2020] |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 616.969 |
| Collana | Pocket guides to biomedical sciences |
| Soggetto topico |
Medical mycology
Mycoses - Diagnosis |
| ISBN |
1-351-67766-7
1-351-67767-5 1-315-16562-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910799923403321 |
| Boca Raton : , : CRC Press, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro
| Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2020] |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 616.969 |
| Collana | Pocket guides to biomedical sciences |
| Soggetto topico |
Medical mycology
Mycoses - Diagnosis |
| ISBN |
1-351-67766-7
1-351-67767-5 1-315-16562-7 9781315165622 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Contents -- Preface -- Editor -- Contributors -- List of Abbreviations -- 1. Mycological Diagnosis: General Principles -- 1.1 Introduction -- 1.2 Collection of clinical specimens -- 1.3 Mycological processing (conventional tests) -- 1.3.1 Direct microscopic examination -- 1.3.2 Culture -- 1.4 Identification -- 1.4.1 Standard culture-based methods: Phenotypical analysis -- 1.4.2 Culture-independent methods -- 1.4.2.1 Molecular diagnosis -- 1.4.2.2 Immunological diagnosis -- 1.4.2.3 Matrix-assisted laser desorption ionization-time of flight mass spectrometry -- 1.5 Conclusions -- Bibliography -- 2. Antifungal Drugs and Susceptibility Testing of Fungi -- 2.1 Antifungal drugs -- 2.1.1 Cell membrane activity -- 2.1.1.1 Formation of pores on cell membrane -- 2.1.1.2 Inhibition of ergosterol synthesis -- 2.1.2 Intracellular activity -- 2.1.2.1 Griseofulvin -- 2.1.2.2 Pyrimidines -- 2.1.2.3 Pyridine derivatives -- 2.1.3 Cell wall activity -- 2.1.3.1 Echinocandins -- 2.2 Antifungal Susceptibility Testing -- 2.2.1 Methods for antifungal susceptibility testing -- 2.2.2 Minimum inhibitory concentration interpretation: Clinical breakpoints vs. epidemiological cutoff values -- 2.2.3 Automation in antifungal susceptibility testing -- Bibliography -- 3. Candida spp. -- 3.1 General aspects -- 3.2 Laboratory diagnosis -- 3.2.1 Microscopy -- 3.2.2 Culture -- 3.3 Identification methods -- 3.3.1 Conventional -- 3.3.2 Semiautomatic or automatic platforms -- 3.3.3 Molecular identification -- 3.4 Therapeutic options -- References -- 4. Cryptococcus -- 4.1 Introduction -- 4.2 Clinical diagnosis -- 4.3 Laboratory diagnosis -- 4.3.1 Direct exam -- 4.3.2 Capsular antigen detection -- 4.3.3 Isolation and identification of C. neoformans and C. gattii species -- 4.3.4 Histopathology -- 4.4 Therapy.
4.5 Prevention -- References -- 5. Trichosporon -- 5.1 Introduction -- 5.2 Specimen selection, collection, and transport -- 5.3 Specimen processing in the mycology laboratory -- 5.4 Species identification -- 5.5 Rapid diagnostic tests -- 5.6 Serology -- References -- 6. Malassezia -- 6.1 Introduction -- 6.2 Pathophysiology of superficial infections -- 6.3 Clinical manifestations -- 6.4 Laboratory diagnosis -- 6.4.1 Collection of clinical samples -- 6.4.2 Microscopy -- 6.4.3 Culture -- 6.4.4 Identification -- 6.5 Conclusions -- References -- 7. Rhodotorula spp. -- 7.1 Introduction -- 7.2 Predisposing factors and clinical manifestations -- 7.3 Laboratorial diagnosis -- 7.3.1 Mycological diagnosis -- 7.3.1.1 Microscopic and culture findings -- 7.3.2 Identification tools -- References -- 8. Dermatophytes -- 8.1 Historical aspects -- 8.2 Epidemiology -- 8.3 Clinical manifestations -- 8.4 Laboratory diagnosis -- 8.4.1 Growth on special culture media -- 8.4.2 Slide culture -- 8.4.3 Urease production -- 8.4.4 In vitro hair perforation test -- 8.4.5 Vitamin and nutritional tests -- 8.5 DNA-based molecular identification -- 8.6 Identification based on protein profile (matrix-assisted laser desorption/ionization-time of flight) -- 8.7 Main species of dermatophytes -- 8.7.1 The Microsporum genus -- 8.7.1.1 Microsporum canis -- 8.7.1.2 Microsporum ferrugineum -- 8.7.2 The Trichophyton genus -- 8.7.2.1 Trichophyton rubrum -- 8.7.2.2 Trichophyton tonsurans -- 8.7.2.3 Trichophyton interdigitale -- 8.7.2.4 Trichophyton verrucosum -- 8.7.2.5 Trichophyton violaceum -- 8.8 Final considerations -- References -- 9. Aspergillus spp. -- 9.1 Introduction -- 9.2 Types and symptoms of aspergillosis -- 9.2.1 Invasive aspergillosis -- 9.2.2 Aspergilloma -- 9.2.3 Chronic fibrosing pulmonary aspergillosis -- 9.2.4 Allergic aspergillosis -- 9.2.5 Cutaneous aspergillosis. 9.3 Aspergillosis risk factors and prevention -- 9.4 Approach to diagnosis -- 9.5 Resistance in Aspergillus spp. -- References -- 10. Mucorales -- 10.1 Introduction (epidemiology and common mucormycosis agents) -- 10.2 Predisposing factors and pathogenesis -- 10.3 Clinical features -- 10.4 Diagnosis -- 10.5 Therapy -- References -- 11. Sporothrix spp. -- 11.1 Introduction -- 11.2 Virulence of Sporothrix species -- 11.3 Pathogenesis and clinical features -- 11.4 Sample collection -- 11.5 Direct examination: Mycology and histopathology -- 11.6 Culture of Sporothrix spp. -- 11.7 Molecular identification of Sporothrix species -- 11.8 Developments in the serology of sporotrichosis -- 11.9 Treatment of sporotrichosis and susceptibility to antifungals -- Acknowledgments -- References -- 12. Histoplasma capsulatum -- 12.1 Introduction -- 12.2 Collection, transport, and processing of clinical samples -- 12.3 Direct examination and culture -- 12.4 Cytopathology and histopathology -- 12.5 Immunodiagnostic tests -- 12.5.1 Antibody detection -- 12.5.2 Antigen detection -- 12.6 Molecular diagnostics -- 12.7 Summary and conclusions -- References -- 13. Paracoccidioides Complex -- 13.1 Introduction -- 13.2 Mycological diagnosis of paracoccidioidomycosis -- 13.3 Collection, transport, and processing of clinical specimens -- 13.4 Direct examination -- 13.5 Histopathological examination -- 13.6 Cultural examination -- 13.7 Serological diagnosis -- 13.8 Molecular diagnosis -- Acknowledgments -- References -- 14. Coccidioides -- 14.1 Introduction: General aspects -- 14.2 Collection and transport of clinical samples for mycological diagnosis -- 14.3 Laboratory processing -- 14.3.1 Direct examination -- 14.3.2 Culture -- 14.4 Histopathological findings -- 14.5 Molecular diagnosis -- 14.6 Serological tests -- 14.7 Conclusion -- References -- 15. Pneumocystis jirovecii. 15.1 Introduction -- 15.2 Collection, transport, and processing of samples -- 15.3 Microscopic examination and culture -- 15.4 Immunological test for P. jirovecii antibody detection -- 15.5 Serological biomarkers: (1-3)-ß-D-glucan, lactate dehydrogenase, Krebs von den Lungen-6, and S-adenosylmethionine -- 15.6 Molecular diagnosis of Pneumocystis jirovecii pneumonia -- 15.6.1 Conventional polymerase chain reaction -- 15.6.2 Nested polymerase chain reaction -- 15.6.3 Real-time polymerase chain reaction (qualitative polymerase chain reaction) -- 15.7 Combination testing -- 15.8 Summary and conclusions -- References -- Index. |
| Record Nr. | UNINA-9911102899103321 |
| Boca Raton : , : CRC Press, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro
| Pocket guide to mycological diagnosis / / [edited by] Rossana de Aguiar Cordeiro |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Boca Raton : , : CRC Press, , [2020] |
| Descrizione fisica | 1 online resource (173 pages) |
| Disciplina | 616.969 |
| Collana | Pocket guides to biomedical sciences |
| Soggetto topico |
Medical mycology
Mycoses - Diagnosis |
| ISBN |
1-351-67766-7
1-351-67767-5 1-315-16562-7 9781315165622 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Contents -- Preface -- Editor -- Contributors -- List of Abbreviations -- 1. Mycological Diagnosis: General Principles -- 1.1 Introduction -- 1.2 Collection of clinical specimens -- 1.3 Mycological processing (conventional tests) -- 1.3.1 Direct microscopic examination -- 1.3.2 Culture -- 1.4 Identification -- 1.4.1 Standard culture-based methods: Phenotypical analysis -- 1.4.2 Culture-independent methods -- 1.4.2.1 Molecular diagnosis -- 1.4.2.2 Immunological diagnosis -- 1.4.2.3 Matrix-assisted laser desorption ionization-time of flight mass spectrometry -- 1.5 Conclusions -- Bibliography -- 2. Antifungal Drugs and Susceptibility Testing of Fungi -- 2.1 Antifungal drugs -- 2.1.1 Cell membrane activity -- 2.1.1.1 Formation of pores on cell membrane -- 2.1.1.2 Inhibition of ergosterol synthesis -- 2.1.2 Intracellular activity -- 2.1.2.1 Griseofulvin -- 2.1.2.2 Pyrimidines -- 2.1.2.3 Pyridine derivatives -- 2.1.3 Cell wall activity -- 2.1.3.1 Echinocandins -- 2.2 Antifungal Susceptibility Testing -- 2.2.1 Methods for antifungal susceptibility testing -- 2.2.2 Minimum inhibitory concentration interpretation: Clinical breakpoints vs. epidemiological cutoff values -- 2.2.3 Automation in antifungal susceptibility testing -- Bibliography -- 3. Candida spp. -- 3.1 General aspects -- 3.2 Laboratory diagnosis -- 3.2.1 Microscopy -- 3.2.2 Culture -- 3.3 Identification methods -- 3.3.1 Conventional -- 3.3.2 Semiautomatic or automatic platforms -- 3.3.3 Molecular identification -- 3.4 Therapeutic options -- References -- 4. Cryptococcus -- 4.1 Introduction -- 4.2 Clinical diagnosis -- 4.3 Laboratory diagnosis -- 4.3.1 Direct exam -- 4.3.2 Capsular antigen detection -- 4.3.3 Isolation and identification of C. neoformans and C. gattii species -- 4.3.4 Histopathology -- 4.4 Therapy.
4.5 Prevention -- References -- 5. Trichosporon -- 5.1 Introduction -- 5.2 Specimen selection, collection, and transport -- 5.3 Specimen processing in the mycology laboratory -- 5.4 Species identification -- 5.5 Rapid diagnostic tests -- 5.6 Serology -- References -- 6. Malassezia -- 6.1 Introduction -- 6.2 Pathophysiology of superficial infections -- 6.3 Clinical manifestations -- 6.4 Laboratory diagnosis -- 6.4.1 Collection of clinical samples -- 6.4.2 Microscopy -- 6.4.3 Culture -- 6.4.4 Identification -- 6.5 Conclusions -- References -- 7. Rhodotorula spp. -- 7.1 Introduction -- 7.2 Predisposing factors and clinical manifestations -- 7.3 Laboratorial diagnosis -- 7.3.1 Mycological diagnosis -- 7.3.1.1 Microscopic and culture findings -- 7.3.2 Identification tools -- References -- 8. Dermatophytes -- 8.1 Historical aspects -- 8.2 Epidemiology -- 8.3 Clinical manifestations -- 8.4 Laboratory diagnosis -- 8.4.1 Growth on special culture media -- 8.4.2 Slide culture -- 8.4.3 Urease production -- 8.4.4 In vitro hair perforation test -- 8.4.5 Vitamin and nutritional tests -- 8.5 DNA-based molecular identification -- 8.6 Identification based on protein profile (matrix-assisted laser desorption/ionization-time of flight) -- 8.7 Main species of dermatophytes -- 8.7.1 The Microsporum genus -- 8.7.1.1 Microsporum canis -- 8.7.1.2 Microsporum ferrugineum -- 8.7.2 The Trichophyton genus -- 8.7.2.1 Trichophyton rubrum -- 8.7.2.2 Trichophyton tonsurans -- 8.7.2.3 Trichophyton interdigitale -- 8.7.2.4 Trichophyton verrucosum -- 8.7.2.5 Trichophyton violaceum -- 8.8 Final considerations -- References -- 9. Aspergillus spp. -- 9.1 Introduction -- 9.2 Types and symptoms of aspergillosis -- 9.2.1 Invasive aspergillosis -- 9.2.2 Aspergilloma -- 9.2.3 Chronic fibrosing pulmonary aspergillosis -- 9.2.4 Allergic aspergillosis -- 9.2.5 Cutaneous aspergillosis. 9.3 Aspergillosis risk factors and prevention -- 9.4 Approach to diagnosis -- 9.5 Resistance in Aspergillus spp. -- References -- 10. Mucorales -- 10.1 Introduction (epidemiology and common mucormycosis agents) -- 10.2 Predisposing factors and pathogenesis -- 10.3 Clinical features -- 10.4 Diagnosis -- 10.5 Therapy -- References -- 11. Sporothrix spp. -- 11.1 Introduction -- 11.2 Virulence of Sporothrix species -- 11.3 Pathogenesis and clinical features -- 11.4 Sample collection -- 11.5 Direct examination: Mycology and histopathology -- 11.6 Culture of Sporothrix spp. -- 11.7 Molecular identification of Sporothrix species -- 11.8 Developments in the serology of sporotrichosis -- 11.9 Treatment of sporotrichosis and susceptibility to antifungals -- Acknowledgments -- References -- 12. Histoplasma capsulatum -- 12.1 Introduction -- 12.2 Collection, transport, and processing of clinical samples -- 12.3 Direct examination and culture -- 12.4 Cytopathology and histopathology -- 12.5 Immunodiagnostic tests -- 12.5.1 Antibody detection -- 12.5.2 Antigen detection -- 12.6 Molecular diagnostics -- 12.7 Summary and conclusions -- References -- 13. Paracoccidioides Complex -- 13.1 Introduction -- 13.2 Mycological diagnosis of paracoccidioidomycosis -- 13.3 Collection, transport, and processing of clinical specimens -- 13.4 Direct examination -- 13.5 Histopathological examination -- 13.6 Cultural examination -- 13.7 Serological diagnosis -- 13.8 Molecular diagnosis -- Acknowledgments -- References -- 14. Coccidioides -- 14.1 Introduction: General aspects -- 14.2 Collection and transport of clinical samples for mycological diagnosis -- 14.3 Laboratory processing -- 14.3.1 Direct examination -- 14.3.2 Culture -- 14.4 Histopathological findings -- 14.5 Molecular diagnosis -- 14.6 Serological tests -- 14.7 Conclusion -- References -- 15. Pneumocystis jirovecii. 15.1 Introduction -- 15.2 Collection, transport, and processing of samples -- 15.3 Microscopic examination and culture -- 15.4 Immunological test for P. jirovecii antibody detection -- 15.5 Serological biomarkers: (1-3)-ß-D-glucan, lactate dehydrogenase, Krebs von den Lungen-6, and S-adenosylmethionine -- 15.6 Molecular diagnosis of Pneumocystis jirovecii pneumonia -- 15.6.1 Conventional polymerase chain reaction -- 15.6.2 Nested polymerase chain reaction -- 15.6.3 Real-time polymerase chain reaction (qualitative polymerase chain reaction) -- 15.7 Combination testing -- 15.8 Summary and conclusions -- References -- Index. |
| Record Nr. | UNINA-9911145426603321 |
| Boca Raton : , : CRC Press, , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
