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Current Developments in the Detection and Control of Multi Drug Resistance
| Current Developments in the Detection and Control of Multi Drug Resistance |
| Autore | Kaushik Sanket |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Sharjah : , : Bentham Science Publishers, , 2022 |
| Descrizione fisica | 1 online resource (181 pages) |
| Disciplina | 616.9041 |
| Altri autori (Persone) | SinghNagendra |
| Soggetto topico |
Multidrug resistance
Drug resistance in microorganisms |
| Soggetto non controllato |
Pharmacology
Medical |
| ISBN | 981-5049-87-9 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910862089003321 |
Kaushik Sanket
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| Sharjah : , : Bentham Science Publishers, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Fighting superbugs [[electronic resource] ] : DOD's response to multidrug-resistant infections in military treatment facilities : hearing before the Subcommittee on Oversight and Investigations of the Committee on Armed Services, House of Representatives, One Hundred Eleventh Congress, second session, hearing held September 29, 2010
| Fighting superbugs [[electronic resource] ] : DOD's response to multidrug-resistant infections in military treatment facilities : hearing before the Subcommittee on Oversight and Investigations of the Committee on Armed Services, House of Representatives, One Hundred Eleventh Congress, second session, hearing held September 29, 2010 |
| Pubbl/distr/stampa | Washington : , : U.S. G.P.O., , 2010 |
| Descrizione fisica | 1 online resource (iii, 85 pages) |
| Soggetto topico |
Multidrug resistance
Drug resistance in microorganisms Bacterial diseases - Treatment Bacterial diseases - Prevention Nosocomial infections - Prevention Military hospitals, American |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Fighting superbugs |
| Record Nr. | UNINA-9910703168403321 |
| Washington : , : U.S. G.P.O., , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The global threat of drug-resistant TB : a call to action for World TB Day : briefing and hearing before the Subcommittee on Africa and Global Health of the Committee on Foreign Affairs, House of Representatives, One Hundred Tenth Congress, first session, March 21, 2007
| The global threat of drug-resistant TB : a call to action for World TB Day : briefing and hearing before the Subcommittee on Africa and Global Health of the Committee on Foreign Affairs, House of Representatives, One Hundred Tenth Congress, first session, March 21, 2007 |
| Descrizione fisica | 1 online resource (2 p.) : ill |
| Soggetto topico |
Antitubercular agents - Effectiveness
Drug resistance in microorganisms Multidrug resistance Tuberculosis - Treatment |
| Soggetto non controllato |
Drug resistance in microorganisms
Tuberculosis Medical |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Global Threat of Drug-Resistant TB |
| Record Nr. | UNINA-9910694379503321 |
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Multi-drug resistance in cancer : mechanism and treatment strategies / / edited by Rishabha Malviya, Arun Kumar Singh, and Deepika Yadav
| Multi-drug resistance in cancer : mechanism and treatment strategies / / edited by Rishabha Malviya, Arun Kumar Singh, and Deepika Yadav |
| Pubbl/distr/stampa | Hoboken, NJ : , : John Wiley & Sons, , [2023] |
| Descrizione fisica | 1 online resource (216 pages) |
| Disciplina | 614.5999 |
| Soggetto topico |
Multidrug resistance
Drug resistance in cancer cells Drug interactions |
| Soggetto non controllato |
Pharmacology
Medical |
| ISBN |
1-394-20986-X
1-394-20985-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright Page -- Contents -- Foreword -- Preface -- Acknowledgment -- Chapter 1 Multi-Drug Rmesistance in Cancer: Understanding of Treatment Strategies -- 1.1 Introduction -- 1.2 Both Congenital and Developed Resistance to Drugs -- 1.2.1 Intrinsic Resistance -- 1.2.2 Acquired Resistance -- 1.3 Drug-Resistance Mechanisms -- 1.3.1 Increased Efflux of Drugs -- 1.3.2 Impact on Medication Target -- 1.3.3 Improved DNA-Damage Repair -- 1.4 Senescence Escape -- 1.5 Epigenetic Alterations -- 1.6 Tumor Heterogeneity -- 1.7 Tumor Microenvironment -- 1.8 Epithelial to Mesenchymal Transition -- 1.9 Conclusion -- References -- Chapter 2 Understanding Different Mechanisms Involved in Cancer Drug Resistance: Proposing Novel Strategies to Overcome MDR -- 2.1 Introduction -- 2.2 Drug Resistance: Internal and External Variables -- 2.2.1 Phenotypic Variation of Tumors -- 2.2.2 Tumor Microenvironment -- 2.2.3 Cancer Stem Cells -- 2.2.4 Inactivation of the Anticancer Drugs -- 2.2.5 Multi-Drug Resistance -- 2.2.6 Increasing the Release of Drugs Outside the Cell -- 2.2.7 Reducing the Absorption of the Drugs -- 2.2.8 Inhibition of Cell Death (Apoptosis Pathway Blocking) -- 2.3 Improving the Pharmacokinetics -- 2.4 Changing the Aim of the Chemotherapy Agents -- 2.5 Improving the DNA Repair Process -- 2.5.1 Augmentation of a Gene -- 2.5.2 Epigenetic Altering Caused Drug Resistance -- 2.6 MicroRNA in Cancer Drug Resistance -- 2.7 Conclusion -- References -- Chapter 3 Molecular Mechanism of Multi-Drug Resistant Cancer Cells -- 3.1 Introduction -- 3.2 Types of Drug Resistance -- 3.3 Mechanisms of Drug Resistance -- 3.3.1 Drug Efflux via ABC Transporters -- 3.3.2 Permeability Glycoprotein/MDR-1 -- 3.3.3 Multi-Drug Resistance Protein -- 3.3.4 Breast Cancer Resistance Protein -- 3.4 Reduction in Drug Activity and Cellular Absorption.
3.5 Instability in the Genome and Medication Resistance -- 3.5.1 Mutation and Medication Target Alteration -- 3.5.2 Restoration of DNA Integrity -- 3.5.3 Resistant Genes and Epigenetic Modifications -- 3.5.4 Drug Resistance and Programmed Cell Death -- 3.6 RNA Interference Therapy -- 3.7 Methods of Physical Intervention to Treat MDR -- 3.8 Conclusion -- References -- Chapter 4 Natural Products for Clinical Management of Drug Resistant Cancer Cells -- 4.1 Introduction -- 4.2 Resistance Mechanisms -- 4.3 Antitumor Plants for Multi-Drug-Resistant Cells -- 4.4 Qualea Species and Their Medical Applications -- 4.5 Antitumor Activity of Qualea Grandiflora and Qualea Multiflora -- 4.6 Conclusion -- References -- Chapter 5 Understanding of Autophagy to Combat MDR During Anticancer Therapy -- 5.1 Introduction -- 5.2 Mechanisms of Autophagy -- 5.2.1 Phagophore Assembly -- 5.2.2 Autophagosome Formation and Maturation -- 5.2.3 Autolysosome Degradation -- 5.2.4 Core Regulator of Autophagy -- 5.3 Mechanisms of MDR -- 5.4 Correlation Between Autophagy and Multi-Drug Resistance -- 5.5 The Cytoprotective Effect of Autophagy in the Regulation of Multi-Drug Resistance -- 5.6 Increased Autophagy Facilitates Multi-Drug Resistance -- 5.7 Autophagy Inhibition Improves Chemotherapy in MDR Cancers -- 5.8 Overcoming MDR With Autophagic Cell Death -- 5.9 Autophagy Kills Apoptosis-Deficient MDR Cancer Cells -- 5.10 Autophagy Promotes Chemosensitivity -- 5.11 Conclusion -- References -- Chapter 6 Transporter Inhibitors: A Chemotherapeutic Regimen to Improve the Clinical Outcome of Colorectal Cancer -- 6.1 Introduction -- 6.2 CRC Transporters or ATP-Binding Cassette -- 6.2.1 ABC Transporter Family -- 6.2.2 ABC Transporters and CRC Initiation -- 6.2.3 ABC Transporters and the Resistance of Cancer Cells to Chemotherapy. 6.3 Clinical Evidence for the Function of ABC Transporters in CRC MDR -- 6.3.1 Intrinsic Drug Resistance in Colon Cancer Upregulation of P-gp at Detection -- 6.3.2 Proliferating Tumor Cells Have MRP1 on Their Surface -- 6.4 General Approaches -- 6.5 By Blocking Tyrosine Kinase Inhibitors from Inhibiting MDR Transporters -- 6.6 Components Produced from Natural Sources that Inhibit MDR Transporters -- 6.7 Inhibiting ABC Transporters in Other Ways for CRC MDR Circumvention -- 6.8 Challenges and Future Prospective -- 6.9 Conclusion -- References -- Chapter 7 Epithelial to Mesenchymal Transition (EMT): Major Contribution to Cancer Drug Therapy Resistance -- 7.1 Introduction -- 7.2 EMT and Tumor Resistance: In Vitro, In Vivo, and Clinical Trials -- 7.3 Tumor Microenvironment Regulates EMT -- 7.3.1 Hypoxia -- 7.3.2 The Extracellular Matrix -- 7.3.3 The Inflammatory and Immune Microenvironment -- 7.3.4 EMT Microenvironment: Medication Resistance -- 7.4 Drug Resistance and EMT Bioinformatics -- 7.4.1 Bioinformatics and Pharmacogenomics to Optimize Drugs and Targets and Identify Medication Resistance -- 7.4.2 Drug Resistance: Hereditary or Acquired -- 7.4.3 Therapies for EMT-Induced Medication Resistance -- 7.5 Conclusion -- References -- Chapter 8 Advances in Metallodrug-Driven Combination Therapy for Treatment of Cancer -- 8.1 Introduction -- 8.2 Cancer Treatment Using Combination Therapy -- 8.3 Combined Treatment with Metallodrugs for Cancer Treatment -- 8.3.1 Platinum Metallodrugs -- 8.4 Nonplatinum Metallodrugs -- 8.5 Conclusion -- References -- Chapter 9 Novel Strategies Preventing Emergence of MDR in Breast Cancer -- 9.1 Introduction -- 9.2 Breast Cancer Categorization and Epidemiological Studies -- 9.2.1 Treatment Options for Women With Breast Cancer -- 9.3 Multi-Drug Resistance in Breast Cancer -- 9.3.1 Breast Cancer Chemoresistance. 9.3.2 Multi-Drug Resistance and ABC Channels in Breast Cancer -- 9.4 Drug Efflux Transporters in Breast Cancer -- 9.4.1 Exocytosis Transporters in the Stem Cell Population of Breast Cancer -- 9.4.2 Drug Efflux Channel Upregulation in Breast Cancer -- 9.4.3 Techniques for Breast Cancer MDR Reversal -- 9.4.4 Direct Pharmacologic Inhibition With MDR Inhibitors -- 9.5 Excessive Synthesis or Overexpression of Transporters for the Expulsion of Drugs -- 9.6 Nanotherapeutic Approach for MDR Reversal -- 9.7 Breast Cancer's MDR Cure Problems and Future Outlook -- 9.8 Conclusion -- References -- Index -- EULA. |
| Record Nr. | UNINA-9910830428803321 |
| Hoboken, NJ : , : John Wiley & Sons, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Multidrug resistance [[electronic resource] ] : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli
| Multidrug resistance [[electronic resource] ] : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli |
| Pubbl/distr/stampa | [United Arab Emirates], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
615.7
615/.7 |
| Altri autori (Persone) |
KhanAsad U
ZarrilliRaffaele |
| Soggetto topico | Multidrug resistance |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-292-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 CONTENTS_revised; 05 PNordmann_Fore_words; 06 Preface; 07 Contributor_and_affiliation; 08 MRP___Drug_Develop_-_02_Shu_Fang_Zaou__2_ _Copie de Hafiz Muhammad Ali en conflit 2011-07-12_; 09 Renato_Klebsiella_Revised _Copie de Hafiz Muhammad Ali en conflit 2011-07-11_; 10 POURNARAS_CONTROL_OF_MDR_SUBMITTED_10_7_2010_revised; 11 Book_Chapter__from_P_Kiratisin__Thailand__revised; 12 Amita_jain_revised; 13 Umesh_Gupta_Drug_Resistance_in_Tuberculosis_Ref_Corrected_; 14 Shazi_and_asad_chapter_corrected
15 Chapter_MRSA_Cabrera_Esperanza_Revised16 Zarrilli_chapter_final_revision_II; 17 Nayak_Chapter_Revised; 18 Noha_KhalafAntibiotic_resistance_in_the_Middle_East_and_N; 19 TaufiqGNB_Saudi_chapter__final_Edited_; 20 Chapter-PERILLI_2__revised; 21 Index |
| Record Nr. | UNINA-9910462128703321 |
| [United Arab Emirates], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Multidrug resistance [[electronic resource] ] : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli
| Multidrug resistance [[electronic resource] ] : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli |
| Pubbl/distr/stampa | [United Arab Emirates], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
615.7
615/.7 |
| Altri autori (Persone) |
KhanAsad U
ZarrilliRaffaele |
| Soggetto topico | Multidrug resistance |
| ISBN | 1-60805-292-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 CONTENTS_revised; 05 PNordmann_Fore_words; 06 Preface; 07 Contributor_and_affiliation; 08 MRP___Drug_Develop_-_02_Shu_Fang_Zaou__2_ _Copie de Hafiz Muhammad Ali en conflit 2011-07-12_; 09 Renato_Klebsiella_Revised _Copie de Hafiz Muhammad Ali en conflit 2011-07-11_; 10 POURNARAS_CONTROL_OF_MDR_SUBMITTED_10_7_2010_revised; 11 Book_Chapter__from_P_Kiratisin__Thailand__revised; 12 Amita_jain_revised; 13 Umesh_Gupta_Drug_Resistance_in_Tuberculosis_Ref_Corrected_; 14 Shazi_and_asad_chapter_corrected
15 Chapter_MRSA_Cabrera_Esperanza_Revised16 Zarrilli_chapter_final_revision_II; 17 Nayak_Chapter_Revised; 18 Noha_KhalafAntibiotic_resistance_in_the_Middle_East_and_N; 19 TaufiqGNB_Saudi_chapter__final_Edited_; 20 Chapter-PERILLI_2__revised; 21 Index |
| Record Nr. | UNINA-9910790164203321 |
| [United Arab Emirates], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Multidrug resistance : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli
| Multidrug resistance : a global concern / / editor, Asad U. Khan ; co-editor, Raffaele Zarrilli |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [United Arab Emirates], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (234 p.) |
| Disciplina |
615.7
615/.7 |
| Altri autori (Persone) |
KhanAsad U
ZarrilliRaffaele |
| Soggetto topico | Multidrug resistance |
| ISBN | 1-60805-292-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
01 Title.pdf; 02 Cover Page; 03 REVISED eBooks End User License Agreement-Website; 04 CONTENTS_revised; 05 PNordmann_Fore_words; 06 Preface; 07 Contributor_and_affiliation; 08 MRP___Drug_Develop_-_02_Shu_Fang_Zaou__2_ _Copie de Hafiz Muhammad Ali en conflit 2011-07-12_; 09 Renato_Klebsiella_Revised _Copie de Hafiz Muhammad Ali en conflit 2011-07-11_; 10 POURNARAS_CONTROL_OF_MDR_SUBMITTED_10_7_2010_revised; 11 Book_Chapter__from_P_Kiratisin__Thailand__revised; 12 Amita_jain_revised; 13 Umesh_Gupta_Drug_Resistance_in_Tuberculosis_Ref_Corrected_; 14 Shazi_and_asad_chapter_corrected
15 Chapter_MRSA_Cabrera_Esperanza_Revised16 Zarrilli_chapter_final_revision_II; 17 Nayak_Chapter_Revised; 18 Noha_KhalafAntibiotic_resistance_in_the_Middle_East_and_N; 19 TaufiqGNB_Saudi_chapter__final_Edited_; 20 Chapter-PERILLI_2__revised; 21 Index |
| Record Nr. | UNINA-9910812806303321 |
| [United Arab Emirates], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
