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Mucoadhesive materials and drug delivery systems / / edited by Vitaliy V. Khutoryanskiy ; Michelle Armstrong [and thirty-one others], contributors
Mucoadhesive materials and drug delivery systems / / edited by Vitaliy V. Khutoryanskiy ; Michelle Armstrong [and thirty-one others], contributors
Pubbl/distr/stampa Chichester, [England] : , : Wiley, , 2014
Descrizione fisica 1 online resource (352 p.)
Disciplina 615.1
Soggetto topico Bioadhesive drug delivery systems
Drug delivery systems
Mucous membrane
ISBN 1-118-79439-7
1-118-79420-6
1-118-79437-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Mucoadhesive Materials and Drug Delivery Systems; Contents; About the Editor; List of Contributors; Preface; Section One: Structure and Physiology of Mucosal Surfaces in Relation to Drug Delivery; 1 Oral Mucosa: Physiological and Physicochemical Aspects; 1.1 Anatomical and Histological Aspects of Oral Cavity Tissues; 1.1.1 Tissue Architecture; 1.1.2 Innervation; 1.1.3 Receptors; 1.2 Production and Composition of Saliva; 1.2.1 Major Salivary Glands; 1.2.2 Minor Salivary Glands; 1.2.3 Saliva Composition; 1.2.4 Mucins; 1.2.5 Proline-rich Proteins; 1.2.6 Statherins; 1.2.7 Cystatins
1.2.8 Histatins1.2.9 Salivary Amylase; 1.2.10 Diversity of Salivary Film; 1.3 Surface Architecture, Mechanical, Rheological and Transport Properties of Salivary Pellicle; 1.3.1 Ex Vivo Pellicle; 1.3.2 Saliva Collection and Handling; 1.3.3 Rheology; 1.3.4 Interfacial Rheology; 1.3.5 Adsorption and Surface Architecture; 1.3.6 Surface Forces; 1.3.7 Lubrication; 1.3.8 Transport Properties; 1.4 Future Perspective; References; 2 Anatomy of the Eye and the Role of Ocular Mucosa in Drug Delivery; 2.1 Introduction; 2.2 Anatomy of the Eye; 2.2.1 Outer Membranes; Conjunctiva, Cornea and Sclera
2.2.2 Aqueous Chamber, Lens and Vitreous Body2.2.3 Choroid and Retina; 2.3 Introduction to Ocular Mucosa; 2.4 The Role of Ocular Mucosa in Drug Delivery; 2.5 Models for Ocular Drug Delivery; 2.6 Recent Advances in Topical Ocular Drug Delivery; 2.6.1 Improving Corneal Retention; 2.6.2 Other Topical Drug Delivery Options; 2.7 Conclusions; References; 3 Drug Delivery Across the Nasal Mucosa; 3.1 Introduction; 3.2 Drug Delivery via the Nasal Mucosa; 3.2.1 Drugs Administered for Local Action; 3.2.2 Drugs Administered for Systemic Effect; 3.2.3 Peptide and Protein Delivery
3.3 Anatomy and Physiology of the Nasal Cavity3.3.1 Structure and Function of the Nasal Cavity; 3.3.2 Nasal Epithelia; 3.3.3 Airflow; 3.3.4 Nasal Secretions; 3.3.5 Mucociliary Clearance; 3.4 Disease States of the Nasal Cavity; 3.4.1 Disease States Altering Drug Absorption; 3.5 Transport Across the Membrane; 3.5.1 Transport Across the Nasal Membrane; 3.5.2 The Solute Carrier Family; 3.5.3 Other Nasal Mucosa Transporters; 3.5.4 Efflux; 3.5.5 Paracellular Transport; 3.6 Nose-to-Brain Drug Delivery; 3.7 Conclusion; References; 4 Gastrointestinal Mucosa and Mucus; 4.1 Introduction
4.1.1 General Gastrointestinal Physiology4.2 The Gastrointestinal Mucus; 4.2.1 What is Mucus?; 4.2.2 Mucus Composition; 4.2.3 Anatomy of Goblet Cells and Mucin Biosynthesis; 4.2.4 Regulation of Mucus Secretion; 4.2.5 Mucus Functions; 4.2.6 Mucus Layer Structure: The Double-Layer Architecture; 4.2.7 Mucus Thickness; 4.2.8 Mucus Rheology; 4.2.9 Mucus Turnover; 4.2.10 Mucus and Ageing; 4.2.11 Mucus and Gastrointestinal Disease; 4.3 Conclusions; References; 5 Vaginal Mucosa and Drug Delivery; 5.1 Introduction; 5.2 Drug Delivery and the Human Vagina
5.2.1 Anatomical and Physiological Considerations
Record Nr. UNINA-9910132201103321
Chichester, [England] : , : Wiley, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucoadhesive materials and drug delivery systems / / edited by Vitaliy V. Khutoryanskiy ; Michelle Armstrong [and thirty-one others], contributors
Mucoadhesive materials and drug delivery systems / / edited by Vitaliy V. Khutoryanskiy ; Michelle Armstrong [and thirty-one others], contributors
Pubbl/distr/stampa Chichester, [England] : , : Wiley, , 2014
Descrizione fisica 1 online resource (352 p.)
Disciplina 615.1
Soggetto topico Bioadhesive drug delivery systems
Drug delivery systems
Mucous membrane
ISBN 1-118-79439-7
1-118-79420-6
1-118-79437-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Mucoadhesive Materials and Drug Delivery Systems; Contents; About the Editor; List of Contributors; Preface; Section One: Structure and Physiology of Mucosal Surfaces in Relation to Drug Delivery; 1 Oral Mucosa: Physiological and Physicochemical Aspects; 1.1 Anatomical and Histological Aspects of Oral Cavity Tissues; 1.1.1 Tissue Architecture; 1.1.2 Innervation; 1.1.3 Receptors; 1.2 Production and Composition of Saliva; 1.2.1 Major Salivary Glands; 1.2.2 Minor Salivary Glands; 1.2.3 Saliva Composition; 1.2.4 Mucins; 1.2.5 Proline-rich Proteins; 1.2.6 Statherins; 1.2.7 Cystatins
1.2.8 Histatins1.2.9 Salivary Amylase; 1.2.10 Diversity of Salivary Film; 1.3 Surface Architecture, Mechanical, Rheological and Transport Properties of Salivary Pellicle; 1.3.1 Ex Vivo Pellicle; 1.3.2 Saliva Collection and Handling; 1.3.3 Rheology; 1.3.4 Interfacial Rheology; 1.3.5 Adsorption and Surface Architecture; 1.3.6 Surface Forces; 1.3.7 Lubrication; 1.3.8 Transport Properties; 1.4 Future Perspective; References; 2 Anatomy of the Eye and the Role of Ocular Mucosa in Drug Delivery; 2.1 Introduction; 2.2 Anatomy of the Eye; 2.2.1 Outer Membranes; Conjunctiva, Cornea and Sclera
2.2.2 Aqueous Chamber, Lens and Vitreous Body2.2.3 Choroid and Retina; 2.3 Introduction to Ocular Mucosa; 2.4 The Role of Ocular Mucosa in Drug Delivery; 2.5 Models for Ocular Drug Delivery; 2.6 Recent Advances in Topical Ocular Drug Delivery; 2.6.1 Improving Corneal Retention; 2.6.2 Other Topical Drug Delivery Options; 2.7 Conclusions; References; 3 Drug Delivery Across the Nasal Mucosa; 3.1 Introduction; 3.2 Drug Delivery via the Nasal Mucosa; 3.2.1 Drugs Administered for Local Action; 3.2.2 Drugs Administered for Systemic Effect; 3.2.3 Peptide and Protein Delivery
3.3 Anatomy and Physiology of the Nasal Cavity3.3.1 Structure and Function of the Nasal Cavity; 3.3.2 Nasal Epithelia; 3.3.3 Airflow; 3.3.4 Nasal Secretions; 3.3.5 Mucociliary Clearance; 3.4 Disease States of the Nasal Cavity; 3.4.1 Disease States Altering Drug Absorption; 3.5 Transport Across the Membrane; 3.5.1 Transport Across the Nasal Membrane; 3.5.2 The Solute Carrier Family; 3.5.3 Other Nasal Mucosa Transporters; 3.5.4 Efflux; 3.5.5 Paracellular Transport; 3.6 Nose-to-Brain Drug Delivery; 3.7 Conclusion; References; 4 Gastrointestinal Mucosa and Mucus; 4.1 Introduction
4.1.1 General Gastrointestinal Physiology4.2 The Gastrointestinal Mucus; 4.2.1 What is Mucus?; 4.2.2 Mucus Composition; 4.2.3 Anatomy of Goblet Cells and Mucin Biosynthesis; 4.2.4 Regulation of Mucus Secretion; 4.2.5 Mucus Functions; 4.2.6 Mucus Layer Structure: The Double-Layer Architecture; 4.2.7 Mucus Thickness; 4.2.8 Mucus Rheology; 4.2.9 Mucus Turnover; 4.2.10 Mucus and Ageing; 4.2.11 Mucus and Gastrointestinal Disease; 4.3 Conclusions; References; 5 Vaginal Mucosa and Drug Delivery; 5.1 Introduction; 5.2 Drug Delivery and the Human Vagina
5.2.1 Anatomical and Physiological Considerations
Record Nr. UNINA-9910807131103321
Chichester, [England] : , : Wiley, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucus and mucosa [[electronic resource]]
Mucus and mucosa [[electronic resource]]
Pubbl/distr/stampa London, : Pitman
Descrizione fisica 1 online resource (258 p.)
Disciplina 611/.0187
Collana Ciba Foundation symposium
Soggetto topico Mucous membrane
Mucus
ISBN 0-212-79783-2
1-280-78416-4
9786613694553
0-470-72090-5
0-470-71860-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Mucus and mucosa; Contents; Introduction; Regulation of secretion from serous and mucous cells in the trachea; Discussion; Regulation of intestinal goblet cells in situ, in mucosal explants and in the isolated epithelium; Discussion; Airway mucus: composition and regulation of its secretion by neuropeptides in vitro; Discussion; Acute and chronic models for hypersecretion of intestinal mucin; Discussion; Proteinases release mucin from airways goblet cells; Discussion; General Discussion Regulation of mucus secretion; Some characteristics of duodenal epithelium; Discussion
Fluid transport across airway epitheliaDiscussion; Some non-mucin components of mucus and their possible biological roles; Discussion; Mucus glycoprotein structure, gel formation and gastrointestinal mucus function; Discussion; Macromolecular properties and polymeric structure of mucus glycoproteins; Discussion; Effects of the anti-oestrogens, clomiphene and tamoxifen, on the cervical factor in female infertility; Terminal glycosylation in human cervical mucin; Discussion of the two preceding papers; Comparative studies of mucus and mucin physicochemistry; Discussion
Hydration kinetics of exocytosed mucins in cultured secretory cells of the rabbit trachea: a new modelDiscussion; Final general discussion Mucus swelling, secretion and effects on cilia; Epithelial preparations; Closing remarks; Index of contributors; Subject index
Record Nr. UNINA-9910144665103321
London, : Pitman
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucus and mucosa [[electronic resource]]
Mucus and mucosa [[electronic resource]]
Pubbl/distr/stampa London, : Pitman
Descrizione fisica 1 online resource (258 p.)
Disciplina 611/.0187
Collana Ciba Foundation symposium
Soggetto topico Mucous membrane
Mucus
ISBN 0-212-79783-2
1-280-78416-4
9786613694553
0-470-72090-5
0-470-71860-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Mucus and mucosa; Contents; Introduction; Regulation of secretion from serous and mucous cells in the trachea; Discussion; Regulation of intestinal goblet cells in situ, in mucosal explants and in the isolated epithelium; Discussion; Airway mucus: composition and regulation of its secretion by neuropeptides in vitro; Discussion; Acute and chronic models for hypersecretion of intestinal mucin; Discussion; Proteinases release mucin from airways goblet cells; Discussion; General Discussion Regulation of mucus secretion; Some characteristics of duodenal epithelium; Discussion
Fluid transport across airway epitheliaDiscussion; Some non-mucin components of mucus and their possible biological roles; Discussion; Mucus glycoprotein structure, gel formation and gastrointestinal mucus function; Discussion; Macromolecular properties and polymeric structure of mucus glycoproteins; Discussion; Effects of the anti-oestrogens, clomiphene and tamoxifen, on the cervical factor in female infertility; Terminal glycosylation in human cervical mucin; Discussion of the two preceding papers; Comparative studies of mucus and mucin physicochemistry; Discussion
Hydration kinetics of exocytosed mucins in cultured secretory cells of the rabbit trachea: a new modelDiscussion; Final general discussion Mucus swelling, secretion and effects on cilia; Epithelial preparations; Closing remarks; Index of contributors; Subject index
Record Nr. UNISA-996202091403316
London, : Pitman
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Mucus and mucosa [[electronic resource]]
Mucus and mucosa [[electronic resource]]
Pubbl/distr/stampa London, : Pitman
Descrizione fisica 1 online resource (258 p.)
Disciplina 611/.0187
Collana Ciba Foundation symposium
Soggetto topico Mucous membrane
Mucus
ISBN 0-212-79783-2
1-280-78416-4
9786613694553
0-470-72090-5
0-470-71860-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Mucus and mucosa; Contents; Introduction; Regulation of secretion from serous and mucous cells in the trachea; Discussion; Regulation of intestinal goblet cells in situ, in mucosal explants and in the isolated epithelium; Discussion; Airway mucus: composition and regulation of its secretion by neuropeptides in vitro; Discussion; Acute and chronic models for hypersecretion of intestinal mucin; Discussion; Proteinases release mucin from airways goblet cells; Discussion; General Discussion Regulation of mucus secretion; Some characteristics of duodenal epithelium; Discussion
Fluid transport across airway epitheliaDiscussion; Some non-mucin components of mucus and their possible biological roles; Discussion; Mucus glycoprotein structure, gel formation and gastrointestinal mucus function; Discussion; Macromolecular properties and polymeric structure of mucus glycoproteins; Discussion; Effects of the anti-oestrogens, clomiphene and tamoxifen, on the cervical factor in female infertility; Terminal glycosylation in human cervical mucin; Discussion of the two preceding papers; Comparative studies of mucus and mucin physicochemistry; Discussion
Hydration kinetics of exocytosed mucins in cultured secretory cells of the rabbit trachea: a new modelDiscussion; Final general discussion Mucus swelling, secretion and effects on cilia; Epithelial preparations; Closing remarks; Index of contributors; Subject index
Record Nr. UNINA-9910829171103321
London, : Pitman
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucus hypersecretion in respiratory disease [[electronic resource]]
Mucus hypersecretion in respiratory disease [[electronic resource]]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Descrizione fisica 1 online resource (304 p.)
Disciplina 616.2
Altri autori (Persone) ChadwickDerek
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Mucous membrane
Respiratory organs - Diseases
Soggetto genere / forma Electronic books.
ISBN 1-280-27111-6
9786610271115
0-470-66827-X
0-470-85929-6
0-470-86079-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MUCUS HYPERSECRETION IN RESPIRATORY DISEASE; Contents; Participants; Chair's introduction; Epidemiological studies in mucus hypersecretion; Discussion; Post-secretory fate of host defence components in mucus; Discussion; Mechanisms of submucosal gland morphogenesis in the airway; Discussion; Mucin-producing elements and inflammatory cells; Discussion; Respiratory tract mucins: structure and expression patterns; Discussion; Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin; Discussion; Regulation of mucin secretion from in vitro cellular models
DiscussionOscillations of pH inside the secretory granule control the gain of Ca(2+) release for signal transduction in goblet cells exocytosis; Discussion; A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction; Discussion; Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR); Discussion; Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways; Discussion
Cytokine regulation of mucus production in a model of allergic asthmaDiscussion; The role of apoptotic regulators in metaplastic mucous cells; Discussion; Current and future therapies for airway mucus hypersecretion; Discussion; Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases; Discussion; Final general discussion; Index of contributors; Subject index
Record Nr. UNINA-9910143168603321
Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucus hypersecretion in respiratory disease [[electronic resource]]
Mucus hypersecretion in respiratory disease [[electronic resource]]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Descrizione fisica 1 online resource (304 p.)
Disciplina 616.2
Altri autori (Persone) ChadwickDerek
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Mucous membrane
Respiratory organs - Diseases
ISBN 1-280-27111-6
9786610271115
0-470-66827-X
0-470-85929-6
0-470-86079-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MUCUS HYPERSECRETION IN RESPIRATORY DISEASE; Contents; Participants; Chair's introduction; Epidemiological studies in mucus hypersecretion; Discussion; Post-secretory fate of host defence components in mucus; Discussion; Mechanisms of submucosal gland morphogenesis in the airway; Discussion; Mucin-producing elements and inflammatory cells; Discussion; Respiratory tract mucins: structure and expression patterns; Discussion; Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin; Discussion; Regulation of mucin secretion from in vitro cellular models
DiscussionOscillations of pH inside the secretory granule control the gain of Ca(2+) release for signal transduction in goblet cells exocytosis; Discussion; A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction; Discussion; Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR); Discussion; Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways; Discussion
Cytokine regulation of mucus production in a model of allergic asthmaDiscussion; The role of apoptotic regulators in metaplastic mucous cells; Discussion; Current and future therapies for airway mucus hypersecretion; Discussion; Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases; Discussion; Final general discussion; Index of contributors; Subject index
Record Nr. UNINA-9910831021203321
Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Mucus hypersecretion in respiratory disease [[electronic resource]]
Mucus hypersecretion in respiratory disease [[electronic resource]]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Descrizione fisica 1 online resource (304 p.)
Disciplina 616.2
Altri autori (Persone) ChadwickDerek
GoodeJamie
Collana Novartis Foundation symposium
Soggetto topico Mucous membrane
Respiratory organs - Diseases
ISBN 1-280-27111-6
9786610271115
0-470-66827-X
0-470-85929-6
0-470-86079-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MUCUS HYPERSECRETION IN RESPIRATORY DISEASE; Contents; Participants; Chair's introduction; Epidemiological studies in mucus hypersecretion; Discussion; Post-secretory fate of host defence components in mucus; Discussion; Mechanisms of submucosal gland morphogenesis in the airway; Discussion; Mucin-producing elements and inflammatory cells; Discussion; Respiratory tract mucins: structure and expression patterns; Discussion; Development and validation of a lectin-based assay for the quantitation of rat respiratory mucin; Discussion; Regulation of mucin secretion from in vitro cellular models
DiscussionOscillations of pH inside the secretory granule control the gain of Ca(2+) release for signal transduction in goblet cells exocytosis; Discussion; A calcium-activated chloride channel blocker inhibits goblet cell metaplasia and mucus overproduction; Discussion; Mechanisms by which Gram-positive bacteria and tobacco smoke stimulate mucin induction through the epidermal growth factor receptor (EGFR); Discussion; Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways; Discussion
Cytokine regulation of mucus production in a model of allergic asthmaDiscussion; The role of apoptotic regulators in metaplastic mucous cells; Discussion; Current and future therapies for airway mucus hypersecretion; Discussion; Clinical evaluation of new therapies for treatment of mucus hypersecretion in respiratory diseases; Discussion; Final general discussion; Index of contributors; Subject index
Record Nr. UNINA-9910841344003321
Chichester, West Sussex, England ; ; Hoboken, NJ, USA, : Wiley, 2002
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Untersuchung zur histologischen Beschaffenheit der Schleimhaut der Sinus paranasales des Pferdes unter Berücksichtigung von Topographie und Alter / / Alexander SChwieder
Untersuchung zur histologischen Beschaffenheit der Schleimhaut der Sinus paranasales des Pferdes unter Berücksichtigung von Topographie und Alter / / Alexander SChwieder
Autore Schwieder Alexander
Pubbl/distr/stampa Göttingen : , : Cuvillier Verlag, , [2018]
Descrizione fisica 1 online resource (158 pages)
Disciplina 616.079
Collana Wissenschaftliche Reihe der Klinik für Pferde
Soggetto topico Mucous membrane
ISBN 3-7369-8801-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione ger
Record Nr. UNINA-9910793513703321
Schwieder Alexander  
Göttingen : , : Cuvillier Verlag, , [2018]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Untersuchung zur histologischen Beschaffenheit der Schleimhaut der Sinus paranasales des Pferdes unter Berücksichtigung von Topographie und Alter / / Alexander SChwieder
Untersuchung zur histologischen Beschaffenheit der Schleimhaut der Sinus paranasales des Pferdes unter Berücksichtigung von Topographie und Alter / / Alexander SChwieder
Autore Schwieder Alexander
Pubbl/distr/stampa Göttingen : , : Cuvillier Verlag, , [2018]
Descrizione fisica 1 online resource (158 pages)
Disciplina 616.079
Collana Wissenschaftliche Reihe der Klinik für Pferde
Soggetto topico Mucous membrane
ISBN 3-7369-8801-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione ger
Record Nr. UNINA-9910819339603321
Schwieder Alexander  
Göttingen : , : Cuvillier Verlag, , [2018]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui