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The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.]
| The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina |
572.591935
599.35/3138 |
| Altri autori (Persone) | LamoreuxM. Lynn |
| Soggetto topico |
Mice - Color - Genetics
Mice as laboratory animals |
| ISBN |
1-282-49198-9
9786612491986 1-4443-1965-5 1-4443-1966-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Colors of Mice; Contents; Preface; Acknowledgments; Statement regarding the use of pictures; Statement regarding nomenclature; Part I Introduction to the Pigmentary System; 1 Introduction to the Pigmentary System; 1.1 Introduction; 1.2 Colors of vertebrate animals; 1.3 Other pigment cells; 1.4 The epidermal melanin unit; 1.5 Mammalian hair; 1.6 Melanosome biogenesis and translocation; 1.7 Melanin; 1.8 Hair growth; 1.9 Hair growth cycles; 1.10 Embryonic development of the pigment cell lineage; 1.11 Pigment cells in culture; 1.12 Conclusion; Appendix: color loci of the mouse
Part II The Pigmentary Loci2 Introduction to Mutant Pigmentary Genes; 2.1 Defects of normal melanocyte development: white spotting and graying with age; 2.2 Defects in normal melanosome development: albinism; 2.3 Transport of melanosomes to other cells: the 'dilute' phenotype; 2.4 Pigment-type switching: from eumelanogenesis to pheomelanogenesis; 3 White Spotting and Progressive Graying; 3.1 Definitions and general background; 3.2 Pigment-cell development: developmental biology; 3.3 Cellular signaling pathways for melanocytes; 3.4 Pigment phenotypes and the classical white-spotting genes 3.5 The head, heart, ears, and eyes4 'Albinism' and the Failure of Normal Melanosome Maturation; 4.1 Background; 4.2 The melanosomal matrix; 4.3 The enzymes that catalyze melanogenesis; 4.4 Membrane proteins that regulate the internal milieu of the melanosome; 4.5 Protein processing and routing to the maturing melanosome; 4.6 Melanosome transport; 5 Pigment-Type Switching; 5.1 Introduction; 5.2 Yellow phenotypes; 5.3 Melanin pigment; 5.4 Melanogenesis and the eumelanin/pheomelanin switch mechanism; 5.5 Signaling the switch mechanism at the cellular level; 5.6 Yellow genes Part III Technology and Resources6 Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation; 6.1 Introduction; 6.2 Mouse transgenesis: generation of genetically engineered mice; 6.3 Coat-color transgenic mice; 6.4 The coat-color mutants generated by gene targeting; 6.5 Influence of the genetic background; 6.6 Conclusions; 7 Other Species and Other Resources; 7.1 Introduction; 7.2 Resources; 7.3 Other species; References; Index |
| Record Nr. | UNINA-9910140612503321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.]
| The colors of mice [[electronic resource] ] : a model genetic network / / M. Lynn Lamoreux ... [et al.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 |
| Descrizione fisica | 1 online resource (311 p.) |
| Disciplina |
572.591935
599.35/3138 |
| Altri autori (Persone) | LamoreuxM. Lynn |
| Soggetto topico |
Mice - Color - Genetics
Mice as laboratory animals |
| ISBN |
1-282-49198-9
9786612491986 1-4443-1965-5 1-4443-1966-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
The Colors of Mice; Contents; Preface; Acknowledgments; Statement regarding the use of pictures; Statement regarding nomenclature; Part I Introduction to the Pigmentary System; 1 Introduction to the Pigmentary System; 1.1 Introduction; 1.2 Colors of vertebrate animals; 1.3 Other pigment cells; 1.4 The epidermal melanin unit; 1.5 Mammalian hair; 1.6 Melanosome biogenesis and translocation; 1.7 Melanin; 1.8 Hair growth; 1.9 Hair growth cycles; 1.10 Embryonic development of the pigment cell lineage; 1.11 Pigment cells in culture; 1.12 Conclusion; Appendix: color loci of the mouse
Part II The Pigmentary Loci2 Introduction to Mutant Pigmentary Genes; 2.1 Defects of normal melanocyte development: white spotting and graying with age; 2.2 Defects in normal melanosome development: albinism; 2.3 Transport of melanosomes to other cells: the 'dilute' phenotype; 2.4 Pigment-type switching: from eumelanogenesis to pheomelanogenesis; 3 White Spotting and Progressive Graying; 3.1 Definitions and general background; 3.2 Pigment-cell development: developmental biology; 3.3 Cellular signaling pathways for melanocytes; 3.4 Pigment phenotypes and the classical white-spotting genes 3.5 The head, heart, ears, and eyes4 'Albinism' and the Failure of Normal Melanosome Maturation; 4.1 Background; 4.2 The melanosomal matrix; 4.3 The enzymes that catalyze melanogenesis; 4.4 Membrane proteins that regulate the internal milieu of the melanosome; 4.5 Protein processing and routing to the maturing melanosome; 4.6 Melanosome transport; 5 Pigment-Type Switching; 5.1 Introduction; 5.2 Yellow phenotypes; 5.3 Melanin pigment; 5.4 Melanogenesis and the eumelanin/pheomelanin switch mechanism; 5.5 Signaling the switch mechanism at the cellular level; 5.6 Yellow genes Part III Technology and Resources6 Novel Mouse Pigmentary Mutants Generated by Genetic Manipulation; 6.1 Introduction; 6.2 Mouse transgenesis: generation of genetically engineered mice; 6.3 Coat-color transgenic mice; 6.4 The coat-color mutants generated by gene targeting; 6.5 Influence of the genetic background; 6.6 Conclusions; 7 Other Species and Other Resources; 7.1 Introduction; 7.2 Resources; 7.3 Other species; References; Index |
| Record Nr. | UNINA-9910828001303321 |
| Chichester, West Sussex ; ; Hoboken, NJ, : Wiley-Blackwell, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Companion guide to Infectious diseases of mice and rats [[electronic resource] /] / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Companion guide to Infectious diseases of mice and rats [[electronic resource] /] / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1991 |
| Descrizione fisica | 1 online resource (105 p.) |
| Disciplina | 636/.93233 |
| Soggetto topico |
Mice - Infections
Rats - Infections Laboratory animals - Infections Mice as laboratory animals Rats as laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-21224-1
9786610212248 0-309-58270-9 0-585-00253-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455900603321 |
| Washington, D.C., : National Academy Press, 1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Companion guide to infectious diseases of mice and rats / / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Companion guide to infectious diseases of mice and rats / / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C. : , : National Academy Press, , 1991 |
| Descrizione fisica | 1 online resource (105 pages) |
| Disciplina | 636/.93233 |
| Soggetto topico |
Mice - Infections
Rats - Infections Laboratory animals - Infections Mice as laboratory animals Rats as laboratory animals |
| ISBN |
1-280-21224-1
9786610212248 0-309-58270-9 0-585-00253-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778505203321 |
| Washington, D.C. : , : National Academy Press, , 1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Companion guide to infectious diseases of mice and rats / / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council
| Companion guide to infectious diseases of mice and rats / / Committee on Infectious Diseases of Mice and Rats, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council |
| Pubbl/distr/stampa | Washington, D.C. : , : National Academy Press, , 1991 |
| Descrizione fisica | 1 online resource (105 pages) |
| Disciplina | 636/.93233 |
| Soggetto topico |
Mice - Infections
Rats - Infections Laboratory animals - Infections Mice as laboratory animals Rats as laboratory animals |
| ISBN |
1-280-21224-1
9786610212248 0-309-58270-9 0-585-00253-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910811948503321 |
| Washington, D.C. : , : National Academy Press, , 1991 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genetics in wild mice : its application to biomedical research / / edited by Kazuo Moriwaki, Toshihiko Shiroishi, Hiromichi Yonekawa
| Genetics in wild mice : its application to biomedical research / / edited by Kazuo Moriwaki, Toshihiko Shiroishi, Hiromichi Yonekawa |
| Pubbl/distr/stampa | S. Karger AG |
| Disciplina | 599.32/33 |
| Altri autori (Persone) |
MoriwakiKazuo
ShiroishiToshihiko YonekowaHiromichi |
| Soggetto topico |
Mice - Genetics
Mice as laboratory animals |
| ISBN | 3-318-05411-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910149655403321 |
| S. Karger AG | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.]
| History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.027333
616.027334 |
| Altri autori (Persone) | FoxJames G |
| Collana |
American College of Laboratory Animal Medicine series
The mouse in biomedical research |
| Soggetto topico |
Mice as laboratory animals
Animal models in research |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-75151-7
9786610751518 0-08-046906-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Mouse in Biomedical Research: History, Wild Mice, and Genetics; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Chapter 1. Building a Better Mouse: One Hundred Years of Genetics and Biology; Chapter 2. Systematics of the genus Mus; Chapter 3. The Secret World of Wild Mice; Chapter 4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types; Chapter 5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide; Chapter 6. The Mouse Genome; Chapter 7. Gene Mapping; Chapter 8. Genetic Monitoring
Chapter 9. CytogeneticsChapter 10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man; Chapter 11. Gamete and Embryo Manipulation; Chapter 12. Chemical Mutagenesis in Mice; Chapter 13. Gene-Specific Mutagenesis; Chapter 14. Gene Transfer Studies Using Mouse Models; Chapter 15. Mouse and Human Pluripotent Stem Cells; Chapter 16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics; Index; Colour Plates |
| Record Nr. | UNINA-9910458628003321 |
| Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.]
| History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.027333
616.027334 |
| Altri autori (Persone) | FoxJames G |
| Collana |
American College of Laboratory Animal Medicine series
The mouse in biomedical research |
| Soggetto topico |
Mice as laboratory animals
Animal models in research |
| ISBN |
1-280-75151-7
9786610751518 0-08-046906-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Mouse in Biomedical Research: History, Wild Mice, and Genetics; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Chapter 1. Building a Better Mouse: One Hundred Years of Genetics and Biology; Chapter 2. Systematics of the genus Mus; Chapter 3. The Secret World of Wild Mice; Chapter 4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types; Chapter 5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide; Chapter 6. The Mouse Genome; Chapter 7. Gene Mapping; Chapter 8. Genetic Monitoring
Chapter 9. CytogeneticsChapter 10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man; Chapter 11. Gamete and Embryo Manipulation; Chapter 12. Chemical Mutagenesis in Mice; Chapter 13. Gene-Specific Mutagenesis; Chapter 14. Gene Transfer Studies Using Mouse Models; Chapter 15. Mouse and Human Pluripotent Stem Cells; Chapter 16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics; Index; Colour Plates |
| Record Nr. | UNINA-9910784640903321 |
| Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.]
| History, wild mice, and genetics [[electronic resource] /] / edited by James G. Fox ... [et al.] |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.027333
616.027334 |
| Altri autori (Persone) | FoxJames G |
| Collana |
American College of Laboratory Animal Medicine series
The mouse in biomedical research |
| Soggetto topico |
Mice as laboratory animals
Animal models in research |
| ISBN |
1-280-75151-7
9786610751518 0-08-046906-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; The Mouse in Biomedical Research: History, Wild Mice, and Genetics; Copyright Page; Table of Contents; List of Reviewers; List of Contributors; Foreword; Preface; Chapter 1. Building a Better Mouse: One Hundred Years of Genetics and Biology; Chapter 2. Systematics of the genus Mus; Chapter 3. The Secret World of Wild Mice; Chapter 4. Breeding Systems: Considerations, Genetic Fundamentals, Genetic Background, and Strain Types; Chapter 5. Mouse Strain and Genetic Nomenclature: an Abbreviated Guide; Chapter 6. The Mouse Genome; Chapter 7. Gene Mapping; Chapter 8. Genetic Monitoring
Chapter 9. CytogeneticsChapter 10. Mouse Embryology: Research Techniques and a Comparison of Embryonic Development between Mouse and Man; Chapter 11. Gamete and Embryo Manipulation; Chapter 12. Chemical Mutagenesis in Mice; Chapter 13. Gene-Specific Mutagenesis; Chapter 14. Gene Transfer Studies Using Mouse Models; Chapter 15. Mouse and Human Pluripotent Stem Cells; Chapter 16. Drugs and the Mouse: Pharmacology, Pharmacogenetics, and Pharmacogenomics; Index; Colour Plates |
| Record Nr. | UNINA-9910820440303321 |
| Amsterdam ; ; Boston, MA, : Academic Press, : Elsevier, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Humanized mice [[electronic resource] /] / Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu, editors
| Humanized mice [[electronic resource] /] / Tatsuji Nomura, Takeshi Watanabe, Sonoko Habu, editors |
| Edizione | [1st ed. 2008.] |
| Pubbl/distr/stampa | Berlin, : Springer, 2008 |
| Descrizione fisica | 1 online resource (213 p.) |
| Disciplina | 599.3530724 |
| Altri autori (Persone) |
HabuSonoko
NomuraTatsuji <1922-> WatanabeTakeshi <1940-> |
| Collana | Current topics in microbiology and immunology |
| Soggetto topico |
Mice as laboratory animals
Transgenic mice |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-24190-3
9786611241902 3-540-75647-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Basic Concept of Development and Practical Application of Animal Models for Human Diseases -- Humanized SCID Mouse Models for Biomedical Research -- NOD/Shi-scid IL2r?null (NOG) Mice More Appropriate for Humanized Mouse Models -- Humanizing Bone Marrow in Immune-Deficient Mice -- The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2r?null Mice -- Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System -- Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development -- Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice -- Humanized Mice for Human Retrovirus Infection -- Functional and Phenotypic Characterization of the Humanized BLT Mouse Model -- Novel Metastasis Models of Human Cancer in NOG Mice -- In Vivo Imaging in Humanized Mice. |
| Record Nr. | UNINA-9910450973703321 |
| Berlin, : Springer, 2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
