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Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry / / Joseph J. Stephanos, Anthony W. Addison
Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry / / Joseph J. Stephanos, Anthony W. Addison
Autore Stephanos Joseph J.
Pubbl/distr/stampa Hoboken, New Jersey : , : Wiley, , 2014
Descrizione fisica 1 online resource (451 p.)
Disciplina 572/.6076
Collana Wiley Series in Protein and Peptide Science
Soggetto topico Metalloproteins
ISBN 1-118-80152-0
1-118-80223-3
1-118-80149-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chemistry of Metalloproteins: Problems and Solutions in Bioinorganic Chemistry; Contents; Preface; 1 Introduction; Proteins: Formation, Structures, and Metalloproteins; Organelles and Their Functions; Structure of DNA; Cell Growth and Division; Protein Synthesis; Common Natural α-Amino Acids; Peptide Chain Formation; Protein physiological functions; Structural Features of Proteins; Causes of Polypeptide Chain Folding; Metal Amino Acid Complexes; Comparison of P-O versus M-O Bond Scission Rates for Row 3 Elements; Redox Advantages: Sulfur versus Phosphorus; Bioenergetic Phosphate Derivatives
References2 Alkali and Alkaline Earth Cations; References; 3 Nonredox Metalloenzymes; Carboxypeptidases; What are the main functions of carboxypeptidases?; What are the main types of carboxypeptidases?; What are the requirements to stimulate carboxypeptidase-A and carboxypeptidase-B?; What are the main structural features of carboxypeptidase-A and carboxypeptidase-B?; How can Zn2+ be extracted from carboxypeptidase-A and carboxypeptidase-B?What are the consequences of metal ion removal?; What are the spectral consequences when Zn2+ is replaced by Co2+ in carboxypeptidases?
Describe the role of Zn2+ in carboxypeptidase-A and carboxypeptidase-B.Design models to mimic the role of the metal ion in carboxypeptidase-A and carboxypeptidase-B.; Carbonic Anhydrase; What are the main functions of carbonic anhydrase?; Conversion of carbonic acid to CO2 and H2O is a spontaneous process. Why is carbonic anhydrase needed?; What are the main structural and chemical features of carbonic anhydrase?; Describe the role of the metal ion in carbonic anhydrase.; What are the possible mechanisms that describe the action of carbonic anhydrase?
Design models for the carbonic anhydrase, and what do they reveal?Rate Constants; Alcohol Dehydrogenase; What is the catalytic role and the structural features of the alcohol dehydrogenases?; What is the sequence of events during the reaction of alcohol dehydrogenase?; A number of model systems have been investigated to study the influence of Zn2+ on the reactivity of the carbonyl; give an example.; References; 4 Copper Proteins; Introduction; Electronic Spectra of Copper Ions; What are the structural and spectral features of copper(II)-peptide complexes in the visible region?
ESR Spectra of Copper IonsHow can ESR spectra be used as a ``spectral probe ́ ́ to study copper enzymes?; Define; How do the nuclear-spin of Cu2+ ion and the attached ligands affect the ESR signal? How can the hyperfine and superhyperfine splitting be used as a ``spectral probe ́ ́ for studying the copper enzymes?; How may the spectrochemical series and the stereochemistry affect g-values of Cu2+ ion and what is the significance of All-gll trend?; Copper Proteins
Identify the significant roles of copper in the biological process, classify, give examples, and explain their functions and main chemical properties.
Record Nr. UNINA-9910132185603321
Stephanos Joseph J.  
Hoboken, New Jersey : , : Wiley, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry / / Joseph J. Stephanos, Anthony W. Addison
Chemistry of metalloproteins : problems and solutions in bioinorganic chemistry / / Joseph J. Stephanos, Anthony W. Addison
Autore Stephanos Joseph J.
Pubbl/distr/stampa Hoboken, New Jersey : , : Wiley, , 2014
Descrizione fisica 1 online resource (451 p.)
Disciplina 572/.6076
Collana Wiley Series in Protein and Peptide Science
Soggetto topico Metalloproteins
ISBN 1-118-80152-0
1-118-80223-3
1-118-80149-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chemistry of Metalloproteins: Problems and Solutions in Bioinorganic Chemistry; Contents; Preface; 1 Introduction; Proteins: Formation, Structures, and Metalloproteins; Organelles and Their Functions; Structure of DNA; Cell Growth and Division; Protein Synthesis; Common Natural α-Amino Acids; Peptide Chain Formation; Protein physiological functions; Structural Features of Proteins; Causes of Polypeptide Chain Folding; Metal Amino Acid Complexes; Comparison of P-O versus M-O Bond Scission Rates for Row 3 Elements; Redox Advantages: Sulfur versus Phosphorus; Bioenergetic Phosphate Derivatives
References2 Alkali and Alkaline Earth Cations; References; 3 Nonredox Metalloenzymes; Carboxypeptidases; What are the main functions of carboxypeptidases?; What are the main types of carboxypeptidases?; What are the requirements to stimulate carboxypeptidase-A and carboxypeptidase-B?; What are the main structural features of carboxypeptidase-A and carboxypeptidase-B?; How can Zn2+ be extracted from carboxypeptidase-A and carboxypeptidase-B?What are the consequences of metal ion removal?; What are the spectral consequences when Zn2+ is replaced by Co2+ in carboxypeptidases?
Describe the role of Zn2+ in carboxypeptidase-A and carboxypeptidase-B.Design models to mimic the role of the metal ion in carboxypeptidase-A and carboxypeptidase-B.; Carbonic Anhydrase; What are the main functions of carbonic anhydrase?; Conversion of carbonic acid to CO2 and H2O is a spontaneous process. Why is carbonic anhydrase needed?; What are the main structural and chemical features of carbonic anhydrase?; Describe the role of the metal ion in carbonic anhydrase.; What are the possible mechanisms that describe the action of carbonic anhydrase?
Design models for the carbonic anhydrase, and what do they reveal?Rate Constants; Alcohol Dehydrogenase; What is the catalytic role and the structural features of the alcohol dehydrogenases?; What is the sequence of events during the reaction of alcohol dehydrogenase?; A number of model systems have been investigated to study the influence of Zn2+ on the reactivity of the carbonyl; give an example.; References; 4 Copper Proteins; Introduction; Electronic Spectra of Copper Ions; What are the structural and spectral features of copper(II)-peptide complexes in the visible region?
ESR Spectra of Copper IonsHow can ESR spectra be used as a ``spectral probe ́ ́ to study copper enzymes?; Define; How do the nuclear-spin of Cu2+ ion and the attached ligands affect the ESR signal? How can the hyperfine and superhyperfine splitting be used as a ``spectral probe ́ ́ for studying the copper enzymes?; How may the spectrochemical series and the stereochemistry affect g-values of Cu2+ ion and what is the significance of All-gll trend?; Copper Proteins
Identify the significant roles of copper in the biological process, classify, give examples, and explain their functions and main chemical properties.
Record Nr. UNINA-9910827658903321
Stephanos Joseph J.  
Hoboken, New Jersey : , : Wiley, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metalloproteins : theory, calculations, and experiments / / edited by Art E. Cho, Korea University, Korea, William A. Goddard III, California Institute of Technology, Pasadena, USA
Metalloproteins : theory, calculations, and experiments / / edited by Art E. Cho, Korea University, Korea, William A. Goddard III, California Institute of Technology, Pasadena, USA
Pubbl/distr/stampa Boca Raton, Florida : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (284 p.)
Disciplina 572/.6
Soggetto topico Metalloproteins
ISBN 0-429-13273-5
1-138-89438-9
1-4987-5992-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Contents; Preface; Editors; Contributors; Chapter 1: Advanced Electron Paramagnetic Resonance Studies of the Oxygen-Evolving Complex; Chapter 2: Radical SAM Enzymes and Their Roles in Complex Cluster Assembly; Chapter 3: Density Functional Theory-Based Treatments of Metal-Binding Sites in Metalloenzymes : Challenges and Opportunities; Chapter 4: Catalysis of Methane Oxidation by the Tricopper Cluster in the Particulate Methane Monooxygenase and Biomimetic Tricopper Complexes; Chapter 5: Oxygen-Evolving Complex of Photosystem II : Insights from Computation and Synthetic Models
Chapter 6: Electrifying MetalloenzymesChapter 7: Iron Uptake Mechanism in Ferritin from Helicobacter pylori; Chapter 8: Multiple-Step Electron Flow in Proteins; Chapter 9: Modeling of Ligand Binding to Metalloproteins; Back Cover
Record Nr. UNINA-9910788126003321
Boca Raton, Florida : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metalloproteins : theory, calculations, and experiments / / edited by Art E. Cho, Korea University, Korea, William A. Goddard III, California Institute of Technology, Pasadena, USA
Metalloproteins : theory, calculations, and experiments / / edited by Art E. Cho, Korea University, Korea, William A. Goddard III, California Institute of Technology, Pasadena, USA
Pubbl/distr/stampa Boca Raton, Florida : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (284 p.)
Disciplina 572/.6
Soggetto topico Metalloproteins
ISBN 0-429-13273-5
1-138-89438-9
1-4987-5992-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Contents; Preface; Editors; Contributors; Chapter 1: Advanced Electron Paramagnetic Resonance Studies of the Oxygen-Evolving Complex; Chapter 2: Radical SAM Enzymes and Their Roles in Complex Cluster Assembly; Chapter 3: Density Functional Theory-Based Treatments of Metal-Binding Sites in Metalloenzymes : Challenges and Opportunities; Chapter 4: Catalysis of Methane Oxidation by the Tricopper Cluster in the Particulate Methane Monooxygenase and Biomimetic Tricopper Complexes; Chapter 5: Oxygen-Evolving Complex of Photosystem II : Insights from Computation and Synthetic Models
Chapter 6: Electrifying MetalloenzymesChapter 7: Iron Uptake Mechanism in Ferritin from Helicobacter pylori; Chapter 8: Multiple-Step Electron Flow in Proteins; Chapter 9: Modeling of Ligand Binding to Metalloproteins; Back Cover
Record Nr. UNINA-9910800190703321
Boca Raton, Florida : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metalloproteomics / / Eugene A. Permyakov
Metalloproteomics / / Eugene A. Permyakov
Autore Permiakov E. A (Evgenii Anatolevich)
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, c2009
Descrizione fisica 1 online resource (820 p.)
Disciplina 572/.6
Collana Wiley series in protein and peptide science
Soggetto topico Metalloproteins
Proteomics
ISBN 1-282-27983-1
9786612279836
0-470-44775-3
0-470-44774-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The complexes of metal cations with low-molecular-mass compounds and of metal cations and proteins -- General regularities of the binding of metal cations to proteins -- Experimental methods used for studies of the binding of metal cations -- Calcium, calcium-binding proteins, and their major families -- Interactions of calcium-binding proteins with low-molecular-mass compounds, peptides, proteins, and membranes -- Calcium-binding proteins in various systems -- The binding of magnesium ions to proteins -- The binding of zinc ions to proteins -- The binding of copper ions to proteins -- Iron-binding proteins -- Molybdenum-containing and tungsten-containing proteins -- Proteins containing nickel and cobalt -- Manganese-containing proteins -- Sodium-binding and potassium-binding proteins -- Interactions of metal cations with nucleic acids -- "Non-physiological" metals.
Record Nr. UNINA-9910877646803321
Permiakov E. A (Evgenii Anatolevich)  
Hoboken, N.J., : John Wiley & Sons, c2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metalloproteomics [[electronic resource] /] / Eugene A. Permyakov
Metalloproteomics [[electronic resource] /] / Eugene A. Permyakov
Autore Permi͡akov E. A (Evgeniĭ Anatolʹevich)
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, c2009
Descrizione fisica 1 online resource (820 p.)
Disciplina 572
572.6
Collana Wiley series in protein and peptide science
Soggetto topico Metalloproteins
Proteomics
Soggetto genere / forma Electronic books.
ISBN 1-282-27983-1
9786612279836
0-470-44775-3
0-470-44774-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The complexes of metal cations with low-molecular-mass compounds and of metal cations and proteins -- General regularities of the binding of metal cations to proteins -- Experimental methods used for studies of the binding of metal cations -- Calcium, calcium-binding proteins, and their major families -- Interactions of calcium-binding proteins with low-molecular-mass compounds, peptides, proteins, and membranes -- Calcium-binding proteins in various systems -- The binding of magnesium ions to proteins -- The binding of zinc ions to proteins -- The binding of copper ions to proteins -- Iron-binding proteins -- Molybdenum-containing and tungsten-containing proteins -- Proteins containing nickel and cobalt -- Manganese-containing proteins -- Sodium-binding and potassium-binding proteins -- Interactions of metal cations with nucleic acids -- "Non-physiological" metals.
Record Nr. UNINA-9910139946903321
Permi͡akov E. A (Evgeniĭ Anatolʹevich)  
Hoboken, N.J., : John Wiley & Sons, c2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Metalloproteomics [[electronic resource] /] / Eugene A. Permyakov
Metalloproteomics [[electronic resource] /] / Eugene A. Permyakov
Autore Permi͡akov E. A (Evgeniĭ Anatolʹevich)
Pubbl/distr/stampa Hoboken, N.J., : John Wiley & Sons, c2009
Descrizione fisica 1 online resource (820 p.)
Disciplina 572
572.6
Collana Wiley series in protein and peptide science
Soggetto topico Metalloproteins
Proteomics
ISBN 1-282-27983-1
9786612279836
0-470-44775-3
0-470-44774-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto The complexes of metal cations with low-molecular-mass compounds and of metal cations and proteins -- General regularities of the binding of metal cations to proteins -- Experimental methods used for studies of the binding of metal cations -- Calcium, calcium-binding proteins, and their major families -- Interactions of calcium-binding proteins with low-molecular-mass compounds, peptides, proteins, and membranes -- Calcium-binding proteins in various systems -- The binding of magnesium ions to proteins -- The binding of zinc ions to proteins -- The binding of copper ions to proteins -- Iron-binding proteins -- Molybdenum-containing and tungsten-containing proteins -- Proteins containing nickel and cobalt -- Manganese-containing proteins -- Sodium-binding and potassium-binding proteins -- Interactions of metal cations with nucleic acids -- "Non-physiological" metals.
Record Nr. UNINA-9910830831703321
Permi͡akov E. A (Evgeniĭ Anatolʹevich)  
Hoboken, N.J., : John Wiley & Sons, c2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
Pubbl/distr/stampa Berlin : , : De Gruyter, , [2016]
Descrizione fisica 1 online resource (188 p.)
Disciplina 572/.51
Soggetto topico Bioinorganic chemistry
Enzyme inhibitors
Metalloproteins
Proteins
Soggetto genere / forma Electronic books.
ISBN 3-11-034890-X
3-11-038644-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Preface -- Contents -- List of Contributing Authors -- 1. Noncovalent interactions in biocomplexes / Yamauchi, Osamu -- 2. Photo-sensitive complexes based on azobenzene / Tylkowski, Bartosz / Jastrząb, Renata / Skrobańska, Monika -- 3. Complexes of biogenic amines in their role in living systems / Jastrząb, Renata / Łomozik, Lechosław / Tylkowski, Bartosz -- 4. Synthetic aspects, crystal structures and biological activities of d- and f-metal salen-type complexes / Kaczmarek, Małgorzata T. -- 5. Biocomplexes in radiochemistry / Ogawa, Kazuma -- 6. Peptides and biocomplexes in anticancer therapy / Khalil, Hadi / Heulot, Mathieu / Barras, David -- 7. Developments in platinum anticancer drugs / Tylkowski, Bartosz / Jastrząb, Renata / Odani, Akira -- Index
Record Nr. UNINA-9910466254603321
Berlin : , : De Gruyter, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
Pubbl/distr/stampa Berlin : , : De Gruyter, , [2016]
Descrizione fisica 1 online resource (188 p.)
Disciplina 572/.51
Soggetto topico Bioinorganic chemistry
Enzyme inhibitors
Metalloproteins
Proteins
ISBN 3-11-034890-X
3-11-038644-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Preface -- Contents -- List of Contributing Authors -- 1. Noncovalent interactions in biocomplexes / Yamauchi, Osamu -- 2. Photo-sensitive complexes based on azobenzene / Tylkowski, Bartosz / Jastrząb, Renata / Skrobańska, Monika -- 3. Complexes of biogenic amines in their role in living systems / Jastrząb, Renata / Łomozik, Lechosław / Tylkowski, Bartosz -- 4. Synthetic aspects, crystal structures and biological activities of d- and f-metal salen-type complexes / Kaczmarek, Małgorzata T. -- 5. Biocomplexes in radiochemistry / Ogawa, Kazuma -- 6. Peptides and biocomplexes in anticancer therapy / Khalil, Hadi / Heulot, Mathieu / Barras, David -- 7. Developments in platinum anticancer drugs / Tylkowski, Bartosz / Jastrząb, Renata / Odani, Akira -- Index
Record Nr. UNINA-9910798285303321
Berlin : , : De Gruyter, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
New-generation bioinorganic complexes / / edited by Renata Jastrząb and Bartosz Tylkowski
Pubbl/distr/stampa Berlin : , : De Gruyter, , [2016]
Descrizione fisica 1 online resource (188 p.)
Disciplina 572/.51
Soggetto topico Bioinorganic chemistry
Enzyme inhibitors
Metalloproteins
Proteins
ISBN 3-11-034890-X
3-11-038644-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Frontmatter -- Preface -- Contents -- List of Contributing Authors -- 1. Noncovalent interactions in biocomplexes / Yamauchi, Osamu -- 2. Photo-sensitive complexes based on azobenzene / Tylkowski, Bartosz / Jastrząb, Renata / Skrobańska, Monika -- 3. Complexes of biogenic amines in their role in living systems / Jastrząb, Renata / Łomozik, Lechosław / Tylkowski, Bartosz -- 4. Synthetic aspects, crystal structures and biological activities of d- and f-metal salen-type complexes / Kaczmarek, Małgorzata T. -- 5. Biocomplexes in radiochemistry / Ogawa, Kazuma -- 6. Peptides and biocomplexes in anticancer therapy / Khalil, Hadi / Heulot, Mathieu / Barras, David -- 7. Developments in platinum anticancer drugs / Tylkowski, Bartosz / Jastrząb, Renata / Odani, Akira -- Index
Record Nr. UNINA-9910822743303321
Berlin : , : De Gruyter, , [2016]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui