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Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta
| Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2003 |
| Descrizione fisica | 1 online resource (538 p.) |
| Disciplina | 616.80471 |
| Altri autori (Persone) | ZattaPaolo |
| Soggetto topico |
Metal ions - Physiological effect
Molecular neurobiology Nervous system - Degeneration Neurotoxicology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-95608-2
9786611956080 981-279-669-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION 2. ANATOMY OF THE OLFACTORY SYSTEM |
| Record Nr. | UNINA-9910454078003321 |
| New Jersey, : World Scientific, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta
| Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2003 |
| Descrizione fisica | 1 online resource (538 p.) |
| Disciplina | 616.80471 |
| Altri autori (Persone) | ZattaPaolo |
| Soggetto topico |
Metal ions - Physiological effect
Molecular neurobiology Nervous system - Degeneration Neurotoxicology |
| ISBN |
1-281-95608-2
9786611956080 981-279-669-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION 2. ANATOMY OF THE OLFACTORY SYSTEM |
| Record Nr. | UNINA-9910782283203321 |
| New Jersey, : World Scientific, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metal ions and neurodegenerative disorders / / editor, Paolo Zatta
| Metal ions and neurodegenerative disorders / / editor, Paolo Zatta |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2003 |
| Descrizione fisica | 1 online resource (538 p.) |
| Disciplina | 616.80471 |
| Altri autori (Persone) | ZattaPaolo |
| Soggetto topico |
Metal ions - Physiological effect
Molecular neurobiology Nervous system - Degeneration Neurotoxicology |
| ISBN |
1-281-95608-2
9786611956080 981-279-669-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper ; 1.5. Zinc 2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease 2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION 2. ANATOMY OF THE OLFACTORY SYSTEM |
| Record Nr. | UNINA-9910814637303321 |
| New Jersey, : World Scientific, c2003 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metal ions in toxicology : effects, interactions, interdependencies
| Metal ions in toxicology : effects, interactions, interdependencies |
| Pubbl/distr/stampa | Berlin : , : De Gruyter, , [2015] |
| Descrizione fisica | 1 online resource (456 pages) : illustrations (some color) |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Metals - Toxicology
Metal ions - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-11-043662-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Historical Development and Perspectives of the Series / Sigel, Astrid / Sigel, Helmut / Sigel, Roland K. O. -- Preface to Volume 8: Metal Ions in Toxicology: Effects, Interactions, Interdependencies -- Contents -- Contributors to Volume 8 -- Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series -- Contents of Volumes in the Metal Ions in Life Sciences Series -- 1 Understanding Combined Effects for Metal Co-Exposure in Ecotoxicology / Altenburger, Rolf -- 2 Human Risk Assessment of Heavy Metals: Principles and Applications / Dorne, Jean-Lou C. M. / Kass, George E. N. / Bordajandi, Luisa R. / Amzal, Billy / Bertelsen, Ulla / Castoldi, Anna F. / Heppner, Claudia / Eskola, Mari / Fabiansson, Stefan / Ferrari, Pietro / Scaravelli, Elena / Dogliotti, Eugenia / Fuerst, Peter / Boobis, Alan R. / Verger, Philippe -- 3 Mixtures and Their Risk Assessment in Toxicology / Mumtaz, Moiz M. / Hansen, Hugh / Pohl, Hana R. -- 4 Metal Ions Affecting the Pulmonary and Cardiovascular Systems / Corradi, Massimo / Mutti, Antonio -- 5 Metal Ions Affecting the Gastrointestinal System Including the Liver / Naughton, Declan P. / Nepusz, Tamás / Petroczi, Andrea -- 6 Metal Ions Affecting the Kidney / Fowler, Bruce A. -- 7 Metal Ions Affecting the Hematological System / Roney, Nickolette / Abadin, Henry G. / Fowler, Bruce / Pohl, Hana R. -- 8 Metal Ions Affecting the Immune System / Lehmann, Irina / Sack, Ulrich / Lehmann, Jörg -- 9 Metal Ions Affecting the Skin and Eyes / Lansdown, Alan B. G. -- 10 Metal Ions Affecting the Neurological System / Pohl, Hana R. / Roney, Nickolette / Abadin, Henry G. -- 11 Metal Ions Affecting Reproduction and Development / Apostoli, Pietro / Catalani, Simona -- 12 Are Cadmium and Other Heavy Metal Compounds Acting as Endocrine Disrupters? / Kortenkamp, Andreas -- 13 Genotoxicity of Metal Ions: Chemical Insights / Bal, Wojciech / Protas, Anna Maria / Kasprzak, Kazimierz S. -- 14 Metal Ions in Human Cancer Development / Tokar, Erik J. / Benbrahim-Tallaa, Lamia / Waalkes, Michael P. -- Subject Index |
| Record Nr. | UNINA-9910460801803321 |
| Berlin : , : De Gruyter, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metal ions in toxicology : effects, interactions, interdependencies
| Metal ions in toxicology : effects, interactions, interdependencies |
| Pubbl/distr/stampa | Berlin : , : De Gruyter, , [2015] |
| Descrizione fisica | 1 online resource (456 pages) : illustrations (some color) |
| Disciplina | 615.9253 |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Metals - Toxicology
Metal ions - Physiological effect |
| ISBN | 3-11-043662-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Historical Development and Perspectives of the Series / Sigel, Astrid / Sigel, Helmut / Sigel, Roland K. O. -- Preface to Volume 8: Metal Ions in Toxicology: Effects, Interactions, Interdependencies -- Contents -- Contributors to Volume 8 -- Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series -- Contents of Volumes in the Metal Ions in Life Sciences Series -- 1 Understanding Combined Effects for Metal Co-Exposure in Ecotoxicology / Altenburger, Rolf -- 2 Human Risk Assessment of Heavy Metals: Principles and Applications / Dorne, Jean-Lou C. M. / Kass, George E. N. / Bordajandi, Luisa R. / Amzal, Billy / Bertelsen, Ulla / Castoldi, Anna F. / Heppner, Claudia / Eskola, Mari / Fabiansson, Stefan / Ferrari, Pietro / Scaravelli, Elena / Dogliotti, Eugenia / Fuerst, Peter / Boobis, Alan R. / Verger, Philippe -- 3 Mixtures and Their Risk Assessment in Toxicology / Mumtaz, Moiz M. / Hansen, Hugh / Pohl, Hana R. -- 4 Metal Ions Affecting the Pulmonary and Cardiovascular Systems / Corradi, Massimo / Mutti, Antonio -- 5 Metal Ions Affecting the Gastrointestinal System Including the Liver / Naughton, Declan P. / Nepusz, Tamás / Petroczi, Andrea -- 6 Metal Ions Affecting the Kidney / Fowler, Bruce A. -- 7 Metal Ions Affecting the Hematological System / Roney, Nickolette / Abadin, Henry G. / Fowler, Bruce / Pohl, Hana R. -- 8 Metal Ions Affecting the Immune System / Lehmann, Irina / Sack, Ulrich / Lehmann, Jörg -- 9 Metal Ions Affecting the Skin and Eyes / Lansdown, Alan B. G. -- 10 Metal Ions Affecting the Neurological System / Pohl, Hana R. / Roney, Nickolette / Abadin, Henry G. -- 11 Metal Ions Affecting Reproduction and Development / Apostoli, Pietro / Catalani, Simona -- 12 Are Cadmium and Other Heavy Metal Compounds Acting as Endocrine Disrupters? / Kortenkamp, Andreas -- 13 Genotoxicity of Metal Ions: Chemical Insights / Bal, Wojciech / Protas, Anna Maria / Kasprzak, Kazimierz S. -- 14 Metal Ions in Human Cancer Development / Tokar, Erik J. / Benbrahim-Tallaa, Lamia / Waalkes, Michael P. -- Subject Index |
| Record Nr. | UNINA-9910797445703321 |
| Berlin : , : De Gruyter, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Metal ions in toxicology : effects, interactions, interdependencies
| Metal ions in toxicology : effects, interactions, interdependencies |
| Pubbl/distr/stampa | Berlin : , : De Gruyter, , [2015] |
| Descrizione fisica | 1 online resource (456 pages) : illustrations (some color) |
| Disciplina | 615.9253 |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Metals - Toxicology
Metal ions - Physiological effect |
| ISBN | 3-11-043662-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Frontmatter -- Historical Development and Perspectives of the Series / Sigel, Astrid / Sigel, Helmut / Sigel, Roland K. O. -- Preface to Volume 8: Metal Ions in Toxicology: Effects, Interactions, Interdependencies -- Contents -- Contributors to Volume 8 -- Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series -- Contents of Volumes in the Metal Ions in Life Sciences Series -- 1 Understanding Combined Effects for Metal Co-Exposure in Ecotoxicology / Altenburger, Rolf -- 2 Human Risk Assessment of Heavy Metals: Principles and Applications / Dorne, Jean-Lou C. M. / Kass, George E. N. / Bordajandi, Luisa R. / Amzal, Billy / Bertelsen, Ulla / Castoldi, Anna F. / Heppner, Claudia / Eskola, Mari / Fabiansson, Stefan / Ferrari, Pietro / Scaravelli, Elena / Dogliotti, Eugenia / Fuerst, Peter / Boobis, Alan R. / Verger, Philippe -- 3 Mixtures and Their Risk Assessment in Toxicology / Mumtaz, Moiz M. / Hansen, Hugh / Pohl, Hana R. -- 4 Metal Ions Affecting the Pulmonary and Cardiovascular Systems / Corradi, Massimo / Mutti, Antonio -- 5 Metal Ions Affecting the Gastrointestinal System Including the Liver / Naughton, Declan P. / Nepusz, Tamás / Petroczi, Andrea -- 6 Metal Ions Affecting the Kidney / Fowler, Bruce A. -- 7 Metal Ions Affecting the Hematological System / Roney, Nickolette / Abadin, Henry G. / Fowler, Bruce / Pohl, Hana R. -- 8 Metal Ions Affecting the Immune System / Lehmann, Irina / Sack, Ulrich / Lehmann, Jörg -- 9 Metal Ions Affecting the Skin and Eyes / Lansdown, Alan B. G. -- 10 Metal Ions Affecting the Neurological System / Pohl, Hana R. / Roney, Nickolette / Abadin, Henry G. -- 11 Metal Ions Affecting Reproduction and Development / Apostoli, Pietro / Catalani, Simona -- 12 Are Cadmium and Other Heavy Metal Compounds Acting as Endocrine Disrupters? / Kortenkamp, Andreas -- 13 Genotoxicity of Metal Ions: Chemical Insights / Bal, Wojciech / Protas, Anna Maria / Kasprzak, Kazimierz S. -- 14 Metal Ions in Human Cancer Development / Tokar, Erik J. / Benbrahim-Tallaa, Lamia / Waalkes, Michael P. -- Subject Index |
| Record Nr. | UNINA-9910815057503321 |
| Berlin : , : De Gruyter, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
