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Advances in Metabolic Profiling of Biological Samples / / Joana Pinto, editor
| Advances in Metabolic Profiling of Biological Samples / / Joana Pinto, editor |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 |
| Descrizione fisica | 1 online resource (186 pages) |
| Disciplina | 570.285 |
| Soggetto topico | Metabolites |
| ISBN | 3-0365-7422-0 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910719776103321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activity of Natural Secondary Metabolite Products / / edited by Toshio Morikawa
| Biological Activity of Natural Secondary Metabolite Products / / edited by Toshio Morikawa |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2018] |
| Descrizione fisica | 1 online resource (466 pages) |
| Disciplina | 570.285 |
| Soggetto topico |
Metabolites
Metabolism, Secondary Natural products - Metabolism |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | About the Special Issue Editor -- Preface to "Biological Activity of Natural Secondary Metabolite Products" -- Tapirira guianensis Aubl. Extracts Inhibit Proliferation and Migration of Oral Cancer Cells Lines -- Berberine Suppresses Cyclin D1 Expression through Proteasomal Degradation in Human Hepatoma Cells -- The Antiproliferative Effect of Chakasaponins I and II, Floratheasaponin A, and Epigallocatechin 3-O-Gallate Isolated from Camellia sinensis on Human Digestive Tract Carcinoma Cell Lines -- Hepatoprotective Effect of Cuscuta campestris Yunck. Whole Plant on Carbon Tetrachloride Induced Chronic Liver Injury in Mice -- Chemical Composition and Antioxidant Activity of Euterpe oleracea Roots and Leaflets -- New Abietane and Kaurane Type Diterpenoids from the Stems of Tripterygium regelii -- Affinin (Spilanthol), Isolated from Heliopsis longipes, Induces Vasodilation via Activation of Gasotransmitters and Prostacyclin Signaling Pathways -- Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis -- Phytochemical Analysis of Agrimonia pilosa Ledeb, Its Antioxidant Activity and Aldose Reductase Inhibitory Potential -- Hazelnut (Corylus avellana L.) Shells Extract: Phenolic Composition, Antioxidant Effect and Cytotoxic Activity on Human Cancer Cell Lines -- Quantitative Determination of Stilbenoids and Dihydroisocoumarins in Shorea roxburghii and Evaluation of Their Hepatoprotective Activity -- Vanillin Suppresses Cell Motility by Inhibiting STAT3-Mediated HIF-1a mRNA Expression in Malignant Melanoma Cells -- Hepatoprotective Effects of Nicotiflorin from Nymphaea candida against Concanavalin A-Induced and D-Galactosamine-Induced Liver Injury in Mice -- Profile of Polyphenol Compounds of Five Muscadine Grapes Cultivated in the United States and in Newly Adapted Locations in China -- Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action -- Assessment of Antioxidant and Cytoprotective Potential of Jatropha (Jatropha curcas) Grown in Southern Italy -- Biosynthesis of a-Glucosidase Inhibitors by a Newly Isolated Bacterium, Paenibacillus sp. TKU042 and Its Effect on Reducing Plasma Glucose in a Mouse Model -- Wedelolactone Acts as Proteasome Inhibitor in Breast Cancer Cells -- Acteoside and Isoacteoside Protect Amyloid ß Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo -- Cultivar-Specific Changes in Primary and Secondary Metabolites in Pak Choi (Brassica Rapa, Chinensis Group) by Methyl Jasmonate -- In Vitro Evaluation of the Antioxidant, Cytoprotective, and Antimicrobial Properties of Essential Oil from Pistacia vera L. Variety Bronte Hull -- Antibacterial and Antifungal Activities of Spices -- Fucaceae: A Source of Bioactive Phlorotannins -- Hepatoprotective Role of Hydrangea macrophylla against Sodium Arsenite-Induced Mitochondrial-Dependent Oxidative Stress via the Inhibition of MAPK/Caspase-3 Pathways -- The Alternaria alternata Mycotoxin Alternariol Suppresses Lipopolysaccharide-Induced Inflammation -- Immuno-Modulatory and Anti-Inflammatory Effects of Dihydrogracilin A, a Terpene Derived from the Marine Sponge Dendrilla membranosa. |
| Record Nr. | UNINA-9910598030703321 |
| Basel, Switzerland : , : MDPI - Multidisciplinary Digital Publishing Institute, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biological Activity of Natural Secondary Metabolite Products / / edited by Toshio Morikawa
| Biological Activity of Natural Secondary Metabolite Products / / edited by Toshio Morikawa |
| Pubbl/distr/stampa | Basel, Switzerland : , : MDPI, , 2018 |
| Descrizione fisica | 1 online resource (466 pages) |
| Disciplina | 570.285 |
| Soggetto topico | Metabolites |
| ISBN |
9783038971757
3038971758 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688579803321 |
| Basel, Switzerland : , : MDPI, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Biotransformation and metabolite elucidation of xenobiotics [[electronic resource] /] / edited by Ala F. Nassar
| Biotransformation and metabolite elucidation of xenobiotics [[electronic resource] /] / edited by Ala F. Nassar |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, 2010 |
| Descrizione fisica | 1 online resource (342 p.) |
| Disciplina | 615.9 |
| Altri autori (Persone) | NassarAla F |
| Soggetto topico |
Xenobiotics - Metabolism
Metabolites Biotransformation (Metabolism) |
| ISBN |
1-118-09777-7
1-282-78289-4 9786612782893 0-470-89038-X 0-470-89037-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
BIOTRANSFORMATION AND METABOLITE ELUCIDATION OF XENOBIOTICS; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: HUMAN BIOTRANSFORMATION; CHAPTER 2: ANALYTICAL TOOLS AND APPROACHES FOR METABOLITE IDENTIFICATION IN DRUG METABOLISM; CHAPTER 3: TOOLS OF CHOICE FOR ACCELERATING METABOLITE IDENTIFICATION: MASS SPECTROMETRY TECHNOLOGY DRIVES METABOLITE IDENTIFICATION STUDIES FORWARD; CHAPTER 4: IMPROVING DRUG DESIGN: CONSIDERATIONS FOR THE STRUCTURAL MODIFICATION PROCESS
CHAPTER 5: CASE STUDY: THE UNANTICIPATED LOSS OF N2 FROM NOVEL DNA ALKYLATING AGENT LAROMUSTINE BY COLLISION-INDUCED DISSOCIATION: NOVEL REARRANGEMENTSCHAPTER 6: CASE STUDY: IDENTIFICATION OF IN VITRO METABOLITE/DECOMPOSITION PRODUCTS OF THE NOVEL DNA ALKYLATING AGENT LAROMUSTINE; CHAPTER 7: STRATEGIES FOR THE DETECTION OF REACTIVE INTERMEDIATES IN DRUG DISCOVERY AND DEVELOPMENT; CHAPTER 8: SAFETY TESTING OF DRUG METABOLITES: MIST GUIDANCE IMPACT ON THE PRACTICE OF INDUSTRIAL DRUG METABOLISM; INDEX |
| Record Nr. | UNINA-9910140760703321 |
| Hoboken, N.J., : John Wiley & Sons, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biotransformation and metabolite elucidation of xenobiotics / / edited by Ala F. Nassar
| Biotransformation and metabolite elucidation of xenobiotics / / edited by Ala F. Nassar |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : John Wiley & Sons, 2010 |
| Descrizione fisica | 1 online resource (342 p.) |
| Disciplina | 615.9 |
| Altri autori (Persone) | NassarAla F |
| Soggetto topico |
Xenobiotics - Metabolism
Metabolites Biotransformation (Metabolism) |
| ISBN |
9786612782893
9781118097779 1118097777 9781282782891 1282782894 9780470890387 047089038X 9780470890370 0470890371 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
BIOTRANSFORMATION AND METABOLITE ELUCIDATION OF XENOBIOTICS; CONTENTS; PREFACE; CONTRIBUTORS; CHAPTER 1: HUMAN BIOTRANSFORMATION; CHAPTER 2: ANALYTICAL TOOLS AND APPROACHES FOR METABOLITE IDENTIFICATION IN DRUG METABOLISM; CHAPTER 3: TOOLS OF CHOICE FOR ACCELERATING METABOLITE IDENTIFICATION: MASS SPECTROMETRY TECHNOLOGY DRIVES METABOLITE IDENTIFICATION STUDIES FORWARD; CHAPTER 4: IMPROVING DRUG DESIGN: CONSIDERATIONS FOR THE STRUCTURAL MODIFICATION PROCESS
CHAPTER 5: CASE STUDY: THE UNANTICIPATED LOSS OF N2 FROM NOVEL DNA ALKYLATING AGENT LAROMUSTINE BY COLLISION-INDUCED DISSOCIATION: NOVEL REARRANGEMENTSCHAPTER 6: CASE STUDY: IDENTIFICATION OF IN VITRO METABOLITE/DECOMPOSITION PRODUCTS OF THE NOVEL DNA ALKYLATING AGENT LAROMUSTINE; CHAPTER 7: STRATEGIES FOR THE DETECTION OF REACTIVE INTERMEDIATES IN DRUG DISCOVERY AND DEVELOPMENT; CHAPTER 8: SAFETY TESTING OF DRUG METABOLITES: MIST GUIDANCE IMPACT ON THE PRACTICE OF INDUSTRIAL DRUG METABOLISM; INDEX |
| Record Nr. | UNINA-9910806236703321 |
| Hoboken, N.J., : John Wiley & Sons, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cancer metabolomics : methods and applications / / Shen Hu. Editor
| Cancer metabolomics : methods and applications / / Shen Hu. Editor |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (317 pages) : illustrations |
| Disciplina | 616.994 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cell metabolism
Metabolites Cancer - Molecular aspects Càncer Metabolisme cel·lular |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-51652-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910483495703321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Chemical Diversity of Plant Specialized Metabolites : A Biosynthetic Approach / / Bratati De
| Chemical Diversity of Plant Specialized Metabolites : A Biosynthetic Approach / / Bratati De |
| Autore | De Bratati |
| Edizione | [First edition.] |
| Pubbl/distr/stampa | London, England : , : The Royal Society of Chemistry, , [2023] |
| Descrizione fisica | 1 online resource (320 pages) |
| Disciplina | 572/.42 |
| Soggetto topico |
Plants - Metabolism
Metabolites |
| ISBN |
9781837671472
1837671478 9781837671489 1837671486 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Chemical Diversity of Plant Specialized Metabolites: A Biosynthetic Approach -- Preface -- Contents -- 1 - Introduction -- References -- 2 - Carbohydrates and Glycosides -- 2.1 Carbohydrates -- 2.1.1 Monosaccharides -- 2.1.2 Oligosaccharides -- 2.1.3 Polysaccharides -- 2.1.3.1 Starches -- 2.1.3.2 Cellulose -- 2.1.3.3 Hemicelluloses -- 2.1.3.4 Pectin -- 2.1.3.5 Gums and Mucilages -- 2.1.4 Role of Carbohydrates in Plants -- 2.1.5 Role in Nutrition and Human Health -- 2.1.6 Other Pharmaceutical and Non-pharmaceutical Applications of Plant Carbohydrates -- 2.2 Glycosides -- 2.2.1 Iridoid Glycosides -- 2.2.2 Saponins -- 2.2.3 Cardiac Glycosides -- 2.2.4 Steryl Glycosides -- 2.2.5 Pregnane Glycosides -- 2.2.6 Phenolic Glycosides -- 2.2.7 Glycosylated Lipids -- 2.2.8 Cyanogenic Glycosides -- 2.2.9 Glucosinolates -- References -- 3 - Acetate-Malonate Pathway: Fatty Acids and Polyketides -- 3.1 Fatty Acids -- 3.1.1 Fatty Acid Biosynthesis -- 3.1.1.1 Elongation of Fatty Acids -- 3.1.1.2 Unsaturated Fatty Acids -- 3.1.1.3 Mitochondrial Biosynthesis of Lipoic Acid -- 3.1.2 Unusual Fatty Acids -- 3.1.3 Triacylglycerols -- 3.1.3.1 Waxes -- 3.1.4 Lipid Polyesters -- 3.1.5 Sphingolipids -- 3.1.6 Phyto-oxylipins -- 3.2 Polyketides -- 3.2.1 Polyketide Biosynthesis -- 3.2.2 Polyketide Types -- 3.2.2.1 Complex Polyketides -- 3.2.2.2 Aromatic Polyketides -- References -- 4 - Mevalonate and Methylerythritol Phosphate Pathways: Terpenoids and Steroids -- Compartmentation of Terpenoid Biosynthesis Through MVA and MEP Pathways in Plants -- 4.1 Hemiterpenes -- 4.2 Monoterpenes -- 4.2.1 Iridoids -- 4.2.2 Irregular Monoterpenes -- 4.3 Sesquiterpenes -- 4.3.1 Sesquiterpene Lactones -- 4.4 Diterpenes -- 4.4.1 Acyclic Diterpenes -- 4.4.2 Bicyclic Diterpenes -- 4.4.3 Tricyclic Diterpenes -- 4.4.4 Tetracyclic Diterpenes -- 4.4.5 Macrocyclic Diterpenes.
4.4.6 Other Diterpenes -- 4.5 Sesterterpenes -- 4.6 Triterpenes and Steroids -- 4.6.1 Hopanes -- 4.6.2 Tetracyclic Dammarane Type Triterpenes -- 4.6.3 Pentacyclic Triterpenes and Saponins -- 4.6.3.1 Lupane-type Triterpenes -- 4.6.3.2 Oleanane-type Triterpenes -- 4.6.3.3 Ursane-type Triterpenes -- 4.6.3.4 Friedelane-type Triterpene -- 4.6.4 seco-Terpenes -- 4.6.5 nor-seco-Terpenoids -- 4.6.6 Steroids -- 4.6.6.1 Sterols -- 4.6.6.2 Steroidal Sapogenins -- 4.6.6.3 Steroidal Alkaloids -- 4.6.6.4 Cardiac Glycosides -- 4.6.6.5 Withanolides -- 4.6.6.6 Cucurbitacins -- 4.6.6.7 Brassinosteroids -- 4.6.6.8 Phytoecdysteroids -- 4.6.6.9 Progesterone -- 4.6.6.10 Testosterone and Structurally Related Androstanes -- 4.6.6.11 Oestrogens -- 4.6.6.12 Commercial Production of Steroidal Drugs from Natural Steroids -- 4.7 Tetraterpenes -- 4.7.1 Biosynthesis of Carotenoids -- 4.7.2 Apocarotenoids -- 4.8 Polyterpenes -- Prenylated Electron Carriers -- References -- 5 - Shikimic Acid Pathway: Phenols -- 5.1 Simple Phenols -- 5.2 Phenolic Acids -- 5.3 Lignin -- 5.4 Lignans -- 5.5 Tannins -- 5.5.1 Hydrolysable Tannins -- 5.5.2 Condensed Tannins -- 5.5.3 Complex Tannins -- 5.5.4 Phlorotannins -- 5.6 Phenylpropenes -- 5.7 Betalains -- 5.7.1 Betacyanins -- 5.7.2 Betaxanthins -- 5.8 Coumarins -- 5.9 Flavonoids -- 5.9.1 Chalcones -- 5.9.2 Aurones -- 5.9.3 Flavonoids -- 5.10 Quinoids -- 5.10.1 Benzoquinones -- 5.10.2 Naphthoquinones -- 5.10.3 Anthraquinones -- 5.11 Stilbenes -- 5.12 Xanthones -- 5.13 Curcuminoids -- 5.14 Phlobaphenes -- References -- 6 - Alkaloids -- 6.1 Classification -- 6.2 Ornithine Derived Alkaloids -- 6.2.1 Tropane Alkaloids -- 6.2.2 Pyrrolidine Alkaloids -- 6.2.3 Pyrrolizidine Alkaloids -- 6.3 Aspartate/Lysine Derived Alkaloids -- 6.3.1 Pyridine Alkaloids -- 6.3.2 Piperidine Alkaloids -- 6.3.3 Quinolizidine Alkaloids -- 6.3.4 Indolizidine Alkaloids. 6.3.5 Lycopodium Alkaloids -- 6.4 Tyrosine Derived Alkaloids -- 6.4.1 Isoquinoline Alkaloids -- 6.4.2 Terpenoid Tetrahydroisoquinoline Alkaloids -- 6.4.3 Amaryllidaceae Alkaloids of Isoquinoline Type -- 6.4.4 Phenethylisoquinoline Alkaloids -- 6.5 Histidine Derived Alkaloids -- 6.6 Tryptophan Derived Alkaloids -- 6.6.1 Indole Alkaloids -- Ergot Alkaloids -- 6.6.2 Quinoline Alkaloids -- 6.7 Anthranilic Acid Derived Alkaloids -- 6.8 Pseudoalkaloids -- Purine Alkaloids -- References -- 7 - Essential Oils and Resins -- 7.1 Essential Oils -- 7.1.1 Role in Plants -- 7.1.2 Role in Human Use -- 7.2 Resins -- References -- Subject Index. |
| Record Nr. | UNINA-9910984662303321 |
De Bratati
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| London, England : , : The Royal Society of Chemistry, , [2023] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational metabolomics [[electronic resource] /] / Nabil Semmar
| Computational metabolomics [[electronic resource] /] / Nabil Semmar |
| Autore | Semmar Nabil |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
| Descrizione fisica | 1 online resource (250 p.) |
| Disciplina | 570.285 |
| Collana | Metabolic diseases--laboratory and clinical research |
| Soggetto topico | Metabolites |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61324-267-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | General classification of metabolomic approaches -- Stoichiometry-based approaches -- Correlation-based approaches -- Distances- and similarity indices-based approaches : cluster analysis -- Outliers and extreme cases analysis -- Weighted metabolic profiles analysis -- Time-dependent analysis of metabolic systems. |
| Record Nr. | UNINA-9910461158603321 |
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Semmar Nabil
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||
| New York, : Nova Science Publishers, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational metabolomics [[electronic resource] /] / Nabil Semmar
| Computational metabolomics [[electronic resource] /] / Nabil Semmar |
| Autore | Semmar Nabil |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
| Descrizione fisica | 1 online resource (250 p.) |
| Disciplina | 570.285 |
| Collana | Metabolic diseases--laboratory and clinical research |
| Soggetto topico | Metabolites |
| ISBN | 1-61324-267-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | General classification of metabolomic approaches -- Stoichiometry-based approaches -- Correlation-based approaches -- Distances- and similarity indices-based approaches : cluster analysis -- Outliers and extreme cases analysis -- Weighted metabolic profiles analysis -- Time-dependent analysis of metabolic systems. |
| Record Nr. | UNINA-9910789425303321 |
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Semmar Nabil
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| New York, : Nova Science Publishers, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Computational metabolomics / / Nabil Semmar
| Computational metabolomics / / Nabil Semmar |
| Autore | Semmar Nabil |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New York, : Nova Science Publishers, c2011 |
| Descrizione fisica | 1 online resource (250 p.) |
| Disciplina | 570.285 |
| Collana | Metabolic diseases--laboratory and clinical research |
| Soggetto topico | Metabolites |
| ISBN | 1-61324-267-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | General classification of metabolomic approaches -- Stoichiometry-based approaches -- Correlation-based approaches -- Distances- and similarity indices-based approaches : cluster analysis -- Outliers and extreme cases analysis -- Weighted metabolic profiles analysis -- Time-dependent analysis of metabolic systems. |
| Record Nr. | UNINA-9910964470103321 |
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Semmar Nabil
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| New York, : Nova Science Publishers, c2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Metabolites
(31)
- Food - Composition (3)
- Genomics (3)
- Metabolic profile tests (3)
- Metabolism - Disorders (3)