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Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko
Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (XVIII, 287 p. 67 illus.)
Disciplina 615
Collana NATO Science for Peace and Security Series A: Chemistry and Biology
Soggetto topico Pharmacology
Environmental health
Public health
Medicinal chemistry
Pharmacology/Toxicology
Environmental Health
Public Health
Medicinal Chemistry
ISBN 94-007-6513-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Targeting NF-κB to Prevent Radiation-Induced Carcinogenesis -- Antioxidants as a Bio-Shield against Radiological Weapons; Kedar -- Sensing Mechanisms of the Low-Power Infrared Radiation: From Molecular Target to Clinical Application -- Correction of the Cancer Therapy-Induced Anemia by the Grape Polyphenol Concentrate Enoant -- Radioprotective Properties of Seleno-Methionine with Methionine, Extracts from Basidium Fungi and Exogenous DNA -- Preventing the Harmful Health Effects of Biological Agents. Homocysteine: Neurotoxicity and Hyperexcitability -- Oxidation of Selected Lipids in Low Density Lipoprotein: Effects on Calcium Transients in Isolated Rabbit Cardiomyocytes -- Cerium Oxide Nanoparticles Counteract the Oxidative Stress in Cardiac Progenitor Cells -- Clinical Trial Complexity Measure – Balancing Constraints to Achieve Quality -- Bioactive Compounds from Natural Sources for Prophylaxis and Treatment of the Effects of Radiological, Chemical and Biological Agents. Systemic Approach in Determining the Role of Bioactive Compounds -- Ecological Potential of Plants -- The Protective Effects of Natural Polyphenolic Complexes of Grape Wine on Organisms Exposed to Oxidative and Nitrosative Stress under Diabetes Mellitus -- Protection of Subjects Participating in Clinical Trials -- Adaptive and Mal-Adaptive Signaling in Cells of the Cardiovascular System: Effect of Obesity-Associated Peptides on Human Blood Platelet Activation -- Spontaneous and Induced Mutagenesis: The Necessity and Possibilities of Prevention with the Grape Polyphenolic Concentrate Enoant -- Searching for New Antimicrobial Targets: Na+ Cycle in Energetics of Bacterial Pathogens -- Natural Antimutagens for Environmental Quality Management and Transition to Ecological Civilization -- Biotechnological and Therapeutical Aspects of Defense against Radiological, Chemical and Biological Agents. Grape Polyphenols Attenuate Psychological Stress -- Grape Cane as a Source of Trans-Resveratrol and Trans-Viniferin in the Technology of Biologically Active Compounds and Its Possible Applications -- The Effectiveness of Enoant in the Treatment of Bronchitis in Children -- Toxicology of Adipose Tissue (Adipotoxicology), or Adipose Tissue as a “Toxicrine” Organ -- Opportunity of Remediation of Radionuclide-Contaminated Soils and Growing Ecologically Pure Plant Material via Water-Retaining Polymer -- Bioactive Compounds of Crimean Wines Countering the Stress Experienced by Personnel -- Wine Components Normalize the Cytochrome P450 Content in the Liver and Kidneys of Rats under Neurogenic Stress.
Record Nr. UNINA-9910739406503321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advances in QSAR Modeling : Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences / / edited by Kunal Roy
Advances in QSAR Modeling : Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences / / edited by Kunal Roy
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (X, 555 p. 132 illus., 71 illus. in color.)
Disciplina 615.19
Collana Challenges and Advances in Computational Chemistry and Physics
Soggetto topico Chemistry, Physical and theoretical
Pharmaceutical technology
Environmental chemistry
Food—Biotechnology
Medicinal chemistry
Agriculture
Theoretical and Computational Chemistry
Pharmaceutical Sciences/Technology
Environmental Chemistry
Food Science
Medicinal Chemistry
ISBN 3-319-56850-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Performance parameters and validation practices in QSAR modeling -- Towards interpretable QSAR models -- The use of topological indices in QSAR and QSPR modeling -- The Maximum Common Substructure (MCS) search as a new tool for SAR and QSAR -- The universal approach for structural and physico-chemical interpretation of QSAR/QSPR models -- Generative Topographic Mapping approach -- Monte Carlo methods for solution of tasks in Environmental Sciences -- QSAR in Environmental Research -- QSAR applications for environmental chemical prioritization: Biotransformation of chemicals -- QSAR modeling in environmental risk assessment: application to the prediction of pesticide toxicity -- Counter propagation artificial neural network (CP ANN) models for prediction of carcinogenicity of non congeneric chemicals for regulatory uses -- Strategy for identification of critical nanomaterials properties linked to biological impacts: interlinking of experimental and computational approaches -- QSAR/QSPR modeling in the design of drug candidates with balanced pharmacodynamics and pharmacokinetic properties -- Molecular modeling of food chemicals as potential bioactive compounds -- On application QSARs in Food and Agricultural Sciences: History and Recent Developments.
Record Nr. UNINA-9910254144703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Albumin in Medicine : Pathological and Clinical Applications / / edited by Masaki Otagiri, Victor Tuan Giam Chuang
Albumin in Medicine : Pathological and Clinical Applications / / edited by Masaki Otagiri, Victor Tuan Giam Chuang
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (X, 277 p. 50 illus., 37 illus. in color.)
Disciplina 615
Soggetto topico Pharmacology
Medicinal chemistry
Pharmacology/Toxicology
Medicinal Chemistry
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910149597203321
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Alzheimer’s Disease II / / edited by Michael S. Wolfe
Alzheimer’s Disease II / / edited by Michael S. Wolfe
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (VII, 202 p. 90 illus., 33 illus. in color.)
Disciplina 616.831
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Pharmaceutical technology
Proteins 
Neurosciences
Medicinal Chemistry
Pharmaceutical Sciences/Technology
Receptors
ISBN 3-319-59460-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Targets and Strategies Toward the Development of Alzheimer Therapeutics -- The Design, Development, and Evaluation of BACE1 Inhibitors for the Treatment of Alzheimer’s Disease -- γ-Secretase Modulators as Aβ42-Lowering Pharmacological Agents to Treat Alzheimer’s Disease -- Inhibitors of Tau-Phosphorylating Kinases -- Microtubule-Stabilizing Agents for Alzheimer’s and Other Tauopathies -- PET Imaging Agents for Alzheimer’s Disease.
Record Nr. UNINA-9910254160003321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Amorphous Drugs : Benefits and Challenges / / by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch
Amorphous Drugs : Benefits and Challenges / / by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch
Autore Rams-Baron Marzena
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (230 pages) : illustrations (some color)
Disciplina 615.19
Soggetto topico Medicinal chemistry
Pharmaceutical technology
Phase transitions (Statistical physics)
Thermodynamics
Ceramics
Glass
Composites (Materials)
Composite materials
Biomedical engineering
Medicinal Chemistry
Pharmaceutical Sciences/Technology
Phase Transitions and Multiphase Systems
Ceramics, Glass, Composites, Natural Materials
Biomedical Engineering and Bioengineering
ISBN 3-319-72002-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation.
Record Nr. UNINA-9910298606303321
Rams-Baron Marzena  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) : Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents / / by Taotao Zou
Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) : Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents / / by Taotao Zou
Autore Zou Taotao
Edizione [1st ed. 2016.]
Pubbl/distr/stampa Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016
Descrizione fisica 1 online resource (175 p.)
Disciplina 540
Collana Springer Theses, Recognizing Outstanding Ph.D. Research
Soggetto topico Inorganic chemistry
Medicinal chemistry
Molecular biology
Cancer research
Inorganic Chemistry
Medicinal Chemistry
Molecular Medicine
Cancer Research
ISBN 981-10-0657-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Experimental Section -- Gold(III) Complexes Containing N-Heterocyclic Carbene Ligand Serve as Dual Fluorescent Thiol “Switch-on” Probe and Anti-Cancer Agent -- A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Effectively Inhibits Tumor Growth and Angiogenesis in Vivo -- Luminescent Organoplatinum(II) Complexes Containing Bis(N-Heterocyclic Carbene) Ligands Selectively Target Endoplasmic Reticulum and Induce Potent Phototoxicity -- Summary and Evaluation.
Record Nr. UNINA-9910254023703321
Zou Taotao  
Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antibacterials : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
Antibacterials : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (203 pages)
Disciplina 616.92061
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Biochemistry
Organic chemistry
Medicinal Chemistry
Biochemistry, general
Organic Chemistry
ISBN 3-319-68097-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Antibacterial New Target Discovery: Sentinel Examples, Strategies, and Surveying Success -- The Antibiotic Future -- Synergistic Antibiotic Combinations -- Antibiotic Adjuvants -- Allosteric Inhibition of Bacterial Targets: An Opportunity for Discovery of Novel Antibacterial Classes -- Four Ways to Skin a Cat: Inhibition of Bacterial Topoisomerases Leading to the Clinic -- The Clinical Development of Antibacterial Drugs: A Guide for the Discovery Scientist.
Record Nr. UNINA-9910298598303321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antibacterials : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
Antibacterials : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (222 pages) : illustrations
Disciplina 616.92061
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Biochemistry
Organic chemistry
Medicinal Chemistry
Biochemistry, general
Organic Chemistry
ISBN 3-319-70839-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Nucleoside Natural Product Antibiotics Targetting Microbial Cell Wall Biosynthesis -- The Cyclic Lipopeptide Antibiotics -- Fully Synthetic Tetracyclines: Increasing Chemical Diversity to Combat Multidrug-Resistant Bacterial Infections -- The Antifolates -- The Oxazolidinones.- Sideromycins as Pathogen-Targeted Antibiotics -- Quorum Sensing Inhibitors as Pathoblockers for Pseudomonas aeruginosa Infections: A New Concept in Anti-Infective Drug Discovery.
Record Nr. UNINA-9910298596403321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Antimalarial Natural Products / / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch
Antimalarial Natural Products / / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch
Edizione [1st ed. 2022.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Descrizione fisica 1 online resource (115 pages)
Disciplina 572
Collana Progress in the Chemistry of Organic Natural Products
Soggetto topico Natural products
Medicinal chemistry
Parasitology
Chemistry, Organic
Pharmaceutical chemistry
Natural Products
Medicinal Chemistry
Organic Chemistry
Pharmaceutics
ISBN 3-030-89873-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910733726203321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Application of Computational Techniques in Pharmacy and Medicine / / edited by Leonid Gorb, Victor Kuz'min, Eugene Muratov
Application of Computational Techniques in Pharmacy and Medicine / / edited by Leonid Gorb, Victor Kuz'min, Eugene Muratov
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (556 p.)
Disciplina 054
541.2
570285
610
Collana Challenges and Advances in Computational Chemistry and Physics
Soggetto topico Chemistry, Physical and theoretical
Medicinal chemistry
Pharmacy
Bioinformatics
Medicine
Theoretical and Computational Chemistry
Medicinal Chemistry
Biomedicine, general
ISBN 94-017-9257-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1 Hybrid QM/MM Methods: Treating Electronic Phenomena in Very Large Molecular Systems -- 2 Structure, Thermodynamics and Energetics of Drug-DNA Interactions: Computer Modeling and Experiment -- 3 Formation of DNA Lesions, Its Prevention and Repair -- 4 DNA dependent DNA Polymerases as Targets for Low-Weight Molecular Inhibitors: State of Art and Prospects of Rational Design -- 5 Molecular structures, relative stability, and proton affinities of nucleotides: Broad view and novel findings -- 6 Quantum Chemical Approaches in Modeling the Structure of Quadruplex DNA and Its Interaction with Metal Ions and Small Molecules -- 7 Density Functional Theory Calculations of Enzyme-Inhibitor Interactions in Medicinal Chemistry and Drug Design -- 8 Molecular Dynamics Simulations of Lipid Bilayers with Incorporated Peptides -- 9 Polyphenol Glycosides as Potential Remedies in Kidney Stones Therapy. Experimental Research Supported by Computational Studies -- 10 Quantum-Chemical Investigation of Epoxidic Compounds Transformation. Application for In Vitro and In Vivo Processes Modeling -- 11 Computational Toxicology in Drug Discovery: opportunities and limitations -- 12 Consensus Drug Design Using it Microcosm -- 13 Continuous Molecular Fields Approach Applied to Structure-Activity Modeling -- 14 Quantitative Structure-Pharmacokinetic Relationships of  Drugs within the Framework of Biopharmaceutics Classification System by Using Simplex Representation of Molecular Structure -- 15 (How to) Profit from Molecular Dynamics-based Ensemble Docking -- 16 Cheminformatics on Crossroad of Eras.
Record Nr. UNINA-9910298644203321
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui