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Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents [[electronic resource] ] : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko
| Advanced Bioactive Compounds Countering the Effects of Radiological, Chemical and Biological Agents [[electronic resource] ] : Strategies to Counter Biological Damage / / edited by Grant N. Pierce, Volodymyr I. Mizin, Alexander Omelchenko |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
| Descrizione fisica | 1 online resource (XVIII, 287 p. 67 illus.) |
| Disciplina | 615 |
| Collana | NATO Science for Peace and Security Series A: Chemistry and Biology |
| Soggetto topico |
Pharmacology
Environmental health Public health Medicinal chemistry Pharmacology/Toxicology Environmental Health Public Health Medicinal Chemistry |
| ISBN | 94-007-6513-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Targeting NF-κB to Prevent Radiation-Induced Carcinogenesis -- Antioxidants as a Bio-Shield against Radiological Weapons; Kedar -- Sensing Mechanisms of the Low-Power Infrared Radiation: From Molecular Target to Clinical Application -- Correction of the Cancer Therapy-Induced Anemia by the Grape Polyphenol Concentrate Enoant -- Radioprotective Properties of Seleno-Methionine with Methionine, Extracts from Basidium Fungi and Exogenous DNA -- Preventing the Harmful Health Effects of Biological Agents. Homocysteine: Neurotoxicity and Hyperexcitability -- Oxidation of Selected Lipids in Low Density Lipoprotein: Effects on Calcium Transients in Isolated Rabbit Cardiomyocytes -- Cerium Oxide Nanoparticles Counteract the Oxidative Stress in Cardiac Progenitor Cells -- Clinical Trial Complexity Measure – Balancing Constraints to Achieve Quality -- Bioactive Compounds from Natural Sources for Prophylaxis and Treatment of the Effects of Radiological, Chemical and Biological Agents. Systemic Approach in Determining the Role of Bioactive Compounds -- Ecological Potential of Plants -- The Protective Effects of Natural Polyphenolic Complexes of Grape Wine on Organisms Exposed to Oxidative and Nitrosative Stress under Diabetes Mellitus -- Protection of Subjects Participating in Clinical Trials -- Adaptive and Mal-Adaptive Signaling in Cells of the Cardiovascular System: Effect of Obesity-Associated Peptides on Human Blood Platelet Activation -- Spontaneous and Induced Mutagenesis: The Necessity and Possibilities of Prevention with the Grape Polyphenolic Concentrate Enoant -- Searching for New Antimicrobial Targets: Na+ Cycle in Energetics of Bacterial Pathogens -- Natural Antimutagens for Environmental Quality Management and Transition to Ecological Civilization -- Biotechnological and Therapeutical Aspects of Defense against Radiological, Chemical and Biological Agents. Grape Polyphenols Attenuate Psychological Stress -- Grape Cane as a Source of Trans-Resveratrol and Trans-Viniferin in the Technology of Biologically Active Compounds and Its Possible Applications -- The Effectiveness of Enoant in the Treatment of Bronchitis in Children -- Toxicology of Adipose Tissue (Adipotoxicology), or Adipose Tissue as a “Toxicrine” Organ -- Opportunity of Remediation of Radionuclide-Contaminated Soils and Growing Ecologically Pure Plant Material via Water-Retaining Polymer -- Bioactive Compounds of Crimean Wines Countering the Stress Experienced by Personnel -- Wine Components Normalize the Cytochrome P450 Content in the Liver and Kidneys of Rats under Neurogenic Stress. |
| Record Nr. | UNINA-9910739406503321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Advances in QSAR Modeling [[electronic resource] ] : Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences / / edited by Kunal Roy
| Advances in QSAR Modeling [[electronic resource] ] : Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences / / edited by Kunal Roy |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (X, 555 p. 132 illus., 71 illus. in color.) |
| Disciplina | 615.19 |
| Collana | Challenges and Advances in Computational Chemistry and Physics |
| Soggetto topico |
Chemistry, Physical and theoretical
Pharmaceutical technology Environmental chemistry Food—Biotechnology Medicinal chemistry Agriculture Theoretical and Computational Chemistry Pharmaceutical Sciences/Technology Environmental Chemistry Food Science Medicinal Chemistry |
| ISBN | 3-319-56850-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Performance parameters and validation practices in QSAR modeling -- Towards interpretable QSAR models -- The use of topological indices in QSAR and QSPR modeling -- The Maximum Common Substructure (MCS) search as a new tool for SAR and QSAR -- The universal approach for structural and physico-chemical interpretation of QSAR/QSPR models -- Generative Topographic Mapping approach -- Monte Carlo methods for solution of tasks in Environmental Sciences -- QSAR in Environmental Research -- QSAR applications for environmental chemical prioritization: Biotransformation of chemicals -- QSAR modeling in environmental risk assessment: application to the prediction of pesticide toxicity -- Counter propagation artificial neural network (CP ANN) models for prediction of carcinogenicity of non congeneric chemicals for regulatory uses -- Strategy for identification of critical nanomaterials properties linked to biological impacts: interlinking of experimental and computational approaches -- QSAR/QSPR modeling in the design of drug candidates with balanced pharmacodynamics and pharmacokinetic properties -- Molecular modeling of food chemicals as potential bioactive compounds -- On application QSARs in Food and Agricultural Sciences: History and Recent Developments. |
| Record Nr. | UNINA-9910254144703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Albumin in Medicine [[electronic resource] ] : Pathological and Clinical Applications / / edited by Masaki Otagiri, Victor Tuan Giam Chuang
| Albumin in Medicine [[electronic resource] ] : Pathological and Clinical Applications / / edited by Masaki Otagiri, Victor Tuan Giam Chuang |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (X, 277 p. 50 illus., 37 illus. in color.) |
| Disciplina | 615 |
| Soggetto topico |
Pharmacology
Medicinal chemistry Pharmacology/Toxicology Medicinal Chemistry |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910149597203321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Alzheimer’s Disease II [[electronic resource] /] / edited by Michael S. Wolfe
| Alzheimer’s Disease II [[electronic resource] /] / edited by Michael S. Wolfe |
| Edizione | [1st ed. 2017.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
| Descrizione fisica | 1 online resource (VII, 202 p. 90 illus., 33 illus. in color.) |
| Disciplina | 616.831 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Pharmaceutical technology Proteins Neurosciences Medicinal Chemistry Pharmaceutical Sciences/Technology Receptors |
| ISBN | 3-319-59460-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Targets and Strategies Toward the Development of Alzheimer Therapeutics -- The Design, Development, and Evaluation of BACE1 Inhibitors for the Treatment of Alzheimer’s Disease -- γ-Secretase Modulators as Aβ42-Lowering Pharmacological Agents to Treat Alzheimer’s Disease -- Inhibitors of Tau-Phosphorylating Kinases -- Microtubule-Stabilizing Agents for Alzheimer’s and Other Tauopathies -- PET Imaging Agents for Alzheimer’s Disease. |
| Record Nr. | UNINA-9910254160003321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Amorphous Drugs [[electronic resource] ] : Benefits and Challenges / / by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch
| Amorphous Drugs [[electronic resource] ] : Benefits and Challenges / / by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva, Deliang Zhou, Witold Jamroz, Marian Paluch |
| Autore | Rams-Baron Marzena |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (230 pages) : illustrations (some color) |
| Disciplina | 615.19 |
| Soggetto topico |
Medicinal chemistry
Pharmaceutical technology Phase transitions (Statistical physics) Thermodynamics Ceramics Glass Composites (Materials) Composite materials Biomedical engineering Medicinal Chemistry Pharmaceutical Sciences/Technology Phase Transitions and Multiphase Systems Ceramics, Glass, Composites, Natural Materials Biomedical Engineering and Bioengineering |
| ISBN | 3-319-72002-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Why amorphous drugs? -- Order vs. disorder in the solid state -- Amorphous drug solubility and absorption enhancement -- Amorphous drug preparation methods -- Physical instability - a key problem of amorphous drugs -- Amorphous drug formulation. |
| Record Nr. | UNINA-9910298606303321 |
Rams-Baron Marzena
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) [[electronic resource] ] : Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents / / by Taotao Zou
| Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II) [[electronic resource] ] : Thiol “Switch-on” Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents / / by Taotao Zou |
| Autore | Zou Taotao |
| Edizione | [1st ed. 2016.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 |
| Descrizione fisica | 1 online resource (175 p.) |
| Disciplina | 540 |
| Collana | Springer Theses, Recognizing Outstanding Ph.D. Research |
| Soggetto topico |
Inorganic chemistry
Medicinal chemistry Molecular biology Cancer research Inorganic Chemistry Medicinal Chemistry Molecular Medicine Cancer Research |
| ISBN | 981-10-0657-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Experimental Section -- Gold(III) Complexes Containing N-Heterocyclic Carbene Ligand Serve as Dual Fluorescent Thiol “Switch-on” Probe and Anti-Cancer Agent -- A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N-Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Effectively Inhibits Tumor Growth and Angiogenesis in Vivo -- Luminescent Organoplatinum(II) Complexes Containing Bis(N-Heterocyclic Carbene) Ligands Selectively Target Endoplasmic Reticulum and Induce Potent Phototoxicity -- Summary and Evaluation. |
| Record Nr. | UNINA-9910254023703321 |
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Zou Taotao
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| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antibacterials [[electronic resource] ] : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
| Antibacterials [[electronic resource] ] : Volume II / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (222 pages) : illustrations |
| Disciplina | 616.92061 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Biochemistry Organic chemistry Medicinal Chemistry Biochemistry, general Organic Chemistry |
| ISBN | 3-319-70839-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Nucleoside Natural Product Antibiotics Targetting Microbial Cell Wall Biosynthesis -- The Cyclic Lipopeptide Antibiotics -- Fully Synthetic Tetracyclines: Increasing Chemical Diversity to Combat Multidrug-Resistant Bacterial Infections -- The Antifolates -- The Oxazolidinones.- Sideromycins as Pathogen-Targeted Antibiotics -- Quorum Sensing Inhibitors as Pathoblockers for Pseudomonas aeruginosa Infections: A New Concept in Anti-Infective Drug Discovery. |
| Record Nr. | UNINA-9910298596403321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antibacterials [[electronic resource] ] : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller
| Antibacterials [[electronic resource] ] : Volume I / / edited by Jed F. Fisher, Shahriar Mobashery, Marvin J. Miller |
| Edizione | [1st ed. 2018.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
| Descrizione fisica | 1 online resource (203 pages) |
| Disciplina | 616.92061 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Biochemistry Organic chemistry Medicinal Chemistry Biochemistry, general Organic Chemistry |
| ISBN | 3-319-68097-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Antibacterial New Target Discovery: Sentinel Examples, Strategies, and Surveying Success -- The Antibiotic Future -- Synergistic Antibiotic Combinations -- Antibiotic Adjuvants -- Allosteric Inhibition of Bacterial Targets: An Opportunity for Discovery of Novel Antibacterial Classes -- Four Ways to Skin a Cat: Inhibition of Bacterial Topoisomerases Leading to the Clinic -- The Clinical Development of Antibacterial Drugs: A Guide for the Discovery Scientist. |
| Record Nr. | UNINA-9910298598303321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Antimalarial Natural Products [[electronic resource] /] / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch
| Antimalarial Natural Products [[electronic resource] /] / edited by A. Douglas Kinghorn, Heinz Falk, Simon Gibbons, Yoshinori Asakawa, Ji-Kai Liu, Verena M. Dirsch |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (115 pages) |
| Disciplina | 572 |
| Collana | Progress in the Chemistry of Organic Natural Products |
| Soggetto topico |
Natural products
Medicinal chemistry Parasitology Chemistry, Organic Pharmaceutical chemistry Natural Products Medicinal Chemistry Organic Chemistry Pharmaceutics |
| ISBN | 3-030-89873-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910733726203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Application of Computational Techniques in Pharmacy and Medicine [[electronic resource] /] / edited by Leonid Gorb, Victor Kuz'min, Eugene Muratov
| Application of Computational Techniques in Pharmacy and Medicine [[electronic resource] /] / edited by Leonid Gorb, Victor Kuz'min, Eugene Muratov |
| Edizione | [1st ed. 2014.] |
| Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
| Descrizione fisica | 1 online resource (556 p.) |
| Disciplina |
054
541.2 570285 610 |
| Collana | Challenges and Advances in Computational Chemistry and Physics |
| Soggetto topico |
Chemistry, Physical and theoretical
Medicinal chemistry Pharmacy Bioinformatics Medicine Theoretical and Computational Chemistry Medicinal Chemistry Biomedicine, general |
| ISBN | 94-017-9257-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1 Hybrid QM/MM Methods: Treating Electronic Phenomena in Very Large Molecular Systems -- 2 Structure, Thermodynamics and Energetics of Drug-DNA Interactions: Computer Modeling and Experiment -- 3 Formation of DNA Lesions, Its Prevention and Repair -- 4 DNA dependent DNA Polymerases as Targets for Low-Weight Molecular Inhibitors: State of Art and Prospects of Rational Design -- 5 Molecular structures, relative stability, and proton affinities of nucleotides: Broad view and novel findings -- 6 Quantum Chemical Approaches in Modeling the Structure of Quadruplex DNA and Its Interaction with Metal Ions and Small Molecules -- 7 Density Functional Theory Calculations of Enzyme-Inhibitor Interactions in Medicinal Chemistry and Drug Design -- 8 Molecular Dynamics Simulations of Lipid Bilayers with Incorporated Peptides -- 9 Polyphenol Glycosides as Potential Remedies in Kidney Stones Therapy. Experimental Research Supported by Computational Studies -- 10 Quantum-Chemical Investigation of Epoxidic Compounds Transformation. Application for In Vitro and In Vivo Processes Modeling -- 11 Computational Toxicology in Drug Discovery: opportunities and limitations -- 12 Consensus Drug Design Using it Microcosm -- 13 Continuous Molecular Fields Approach Applied to Structure-Activity Modeling -- 14 Quantitative Structure-Pharmacokinetic Relationships of Drugs within the Framework of Biopharmaceutics Classification System by Using Simplex Representation of Molecular Structure -- 15 (How to) Profit from Molecular Dynamics-based Ensemble Docking -- 16 Cheminformatics on Crossroad of Eras. |
| Record Nr. | UNINA-9910298644203321 |
| Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Medicinal Chemistry
(209)
- Medicinal chemistry (206)
- Organic Chemistry (62)
- Organic chemistry (57)
- Pharmaceutical Sciences/Technology (39)