Advances in Nutrition and Cancer / / edited by Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (450 p.) |
Disciplina |
616.99
616.99/4071 616.994071 |
Collana | Cancer Treatment and Research |
Soggetto topico |
Oncology
Medicine, Preventive Health promotion Epidemiology Medicine - Research Biology - Research Medical genetics Diseases Health Promotion and Disease Prevention Biomedical Research Medical Genetics |
ISBN | 3-642-38007-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I: Life Style, Diet and Cancer: The role of metabolic carcinogenesis in cancer causation and prevention: evidence from the European prospective investigation into cancer and nutrition -- Obesity, energy balance and cancer: a mechanistic perspective -- Fruits and vegetables. Updating the epidemiologic evidence for the WCRF-AICR lifestyle recommendations for cancer prevention -- The diet as a cause of human prostate cancer -- Mediterranean dietary pattern and chronic diseases -- Dietary salt intake and risk of gastric cancer -- Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks -- Part II: Natural Dietary Molecules: Anti-inflammatory and anti-cancer drugs from nature -- Selenium and cancer: a story that should not be forgotten – Insights from genomics -- Resveratrol: from basic studies to bedside -- Quercetin: a pleiotropic kinase inhibitor against cancer -- Sulforaphane as a promising molecule for fighting cancer -- Part III: Genetics and Epigenetics: Functions, aberrations and advances for chromatin modulation in cancer -- Epigenetics and epidemiology: models of study and examples -- Dietary epigenetics in cancer and aging -- Breast cancer and the importance of early life nutrition -- Part IV: Olive Oil in Cancer Prevention -- Olive oil and other dietary lipids in breast cancer -- A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer -- Extra virgin olive oil: from composition to ‘molecular fastronomy’ -- Part V: Life Style Prevention of Cancer: Life style prevention of cancer recurrence: the yin and the yang -- Part VI: Emerging Breakthroughs: New perspective for an old antidiabetic drug: metformin as anticancer agent -- Gut microbes, diet and cancer -- Inflammatory angiogenesis and the tumor microenvironment as targets for cancer therapy and prevention -- Nutriomes and personalised nutrition for DNA damage prevention, telomere integrity maintenance and cancer growth control -- Novel approaches in melanoma prevention and therapy -- Concluding remarks. |
Record Nr. | UNINA-9910300071903321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Biochemical Mechanisms for Metabolic Syndrome / / edited by Tejal Gandhi, Anita Mehta |
Autore | Gandhi Tejal |
Edizione | [1st ed. 2024.] |
Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
Descrizione fisica | 1 online resource (586 pages) |
Disciplina | 572.4 |
Altri autori (Persone) | MehtaAnita |
Collana | Advances in Biochemistry in Health and Disease |
Soggetto topico |
Metabolism
Metabolism - Disorders Biochemistry Cell biology Medical genetics Medical microbiology Metabolic Disease Metabolic Pathways Medical Genetics Medical Microbiology |
ISBN | 9783031756863 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I: Overview and Introduction to Metabolic Syndrome -- 1. The biochemical symphony of metabolic syndrome: An intricate introduction -- 2. Insulin resistance and its biochemical basis in metabolic syndrome -- 3. Lipid metabolism dysregulation: Impact on metabolic syndrome -- 4. The weighty impact: Exploring the importance of obesity in metabolic Syndrome -- 5. Connecting the dots: The complex relationship between metabolic syndrome and hypertension -- 6. The orchestra of genetics: Genetic predisposition to metabolic syndrome Prachi Kariaa and Kirti Patela -- Part II: Cellular and Tissue Mechanisms in Metabolic Syndrome -- 7. cGAS-STING: A regulator of intestinal barrier dysfunction and metabolic syndrome -- 8. Adipose tissue remodeling and metabolic syndrome progression -- 9. Mitochondrial dysfunction, metabolic syndrome and the Pathogenesis of Metabolic Diseases -- Part III. Emerging Molecular Mechanisms and Signaling Pathways -- 10. Inflammatory resolution and its relevance to metabolic syndrome -- 11. Role of Brain Natriuretic Peptide in Metabolic and Hypertrophic Heart Failure -- 12. Endoplasmic reticulum stress and unfolded protein response in metabolic syndrome -- 13. The Impact of Nrf2 Signalling Pathway in Redox Regulation, Inflammation Attenuation, and Management of Metabolic Syndrome: A Systematic Review -- Part IV. Brain-Gut-Adipose Axis and Endocrine Regulation -- 14. Gut Microbiota-derived metabolites and their impact on Obesity -- 15. The Impact of Gut Hormones and the Gut-Adipose-Liver Axis in Metabolic Syndrome: An Overview of Nrf2 Involvement in the Signaling Pathways -- 16. Neuronal regulation of thermogenesis and energy expenditure in Metabolic syndrome -- 17. Endocrine interplay in metabolic syndrome -- Part V. Omics Technologies: Unraveling the Molecular Complexity of Metabolic Syndrome -- 18. Understanding Cardiometabolic Diseases through Transcriptomic approach -- Part VI. Current Therapies and Future Perspectives of Metabolic Syndrome -- 19. Metabolic Syndrome Management through Omega-3 polyunsaturated fatty acids and Antioxidant-Rich Diets: An Approach from Marine and Vegetarian Sources -- 20. Pharmacological Interventions of Metabolic Syndrome -- 21. Metabolic syndrome and associated cognitive dysfunction: a pharmacological perspective -- 22. Brown adipose tissue and its therapeutic potential for Metabolic Syndrome -- 23. Bariatric Surgery and Metabolic Syndrome -- 24. Complementary and Alternative medicine in Metabolic Syndrome Management -- 25. Future Directions and Emerging Research in Metabolic syndrome. |
Record Nr. | UNINA-9910918693403321 |
Gandhi Tejal
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cancer Research: An Interdisciplinary Approach / / edited by Nima Rezaei |
Autore | Rezaei Nima |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2023 |
Descrizione fisica | 1 online resource (614 pages) |
Disciplina | 616.9940072 |
Collana | Interdisciplinary Cancer Research |
Soggetto topico |
Cancer
Cancer—Treatment Stem cells Cytology Medical genetics Immunology Cancer Biology Cancer Therapy Cancer Stem Cells Cell Biology Medical Genetics |
ISBN | 3-031-32458-7 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Interdisciplinary Approaches in Cancer Research -- Role of Immune Cells in the Tumor Microenvironment -- Spatial Transcriptomic Approaches for Understanding the Tumor Microenvironment (TME) -- Role of Mesenchymal Stem/Stromal Cells in Cancer Development -- Cancer-associated Fibroblasts and Their Role in Cancer Progression -- The Role of Tumoroids in Cancer Research -- Myokines Expression in Cancer Cachexia -- Epigenetics in Cancer Biology -- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation -- Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity -- Molecular Mechanisms of Metal-induced Carcinogenesis -- Epi-drugs Targeting RNA Dynamics in Cancer -- Oncologic Emergencies: Pathophysiology, Diagnosis, and Initial Management -- Malignancies in Inborn Errors of Immunity -- Hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity and Malignancy -- Personalized Immuno-oncology with Immunodeficiency Mouse Models -- Allergy and Cancer: New Perspectives -- Depression and Cancer: the Inflammatory Bridge -- Impact of Cancer-Related Sarcopenia on Systemic Immune Status -- Surveillance of Subclinical Cardiovascular Complications in Childhood Cancer Survivors: Exercise as a Diagnostic and Therapeutic Modality. |
Record Nr. | UNINA-9910734848103321 |
Rezaei Nima
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2023 | ||
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Lo trovi qui: Univ. Federico II | ||
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Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications / / edited by Susan C. Frost, Robert McKenna |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (429 p.) |
Disciplina | 572.6 |
Collana | Subcellular Biochemistry |
Soggetto topico |
Medical genetics
Proteins Medicine - Research Biology - Research Medical Genetics Protein Biochemistry Biomedical Research |
ISBN | 94-007-7359-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface. Part I Introduction -- Overview of the Carbonic Anhydrase Field -- Part II Carbonic Anhydrases: Ancient but Relevant. Physiological Functions of the Alpha Class of Carbonic Anhydrases -- Catalytic Mechanism of α-Class Carbonic Anhydrases: CO2 Hydration and Proton Transfer -- Structure and Catalytic Mechanism of b-Carbonic Anhydrases -- Prokaryotic Carbonic Anhydrases of Earth’s Environment -- Carboxysomal Carbonic Anhydrases -- Carbonic Anhydrases and their Interplay with Acid/base-coupled Membrane Transporters -- Carbonic Anhydrase Related Proteins: Molecular Biology and Evolution -- Membrane Associated Carbonic Anhydrase IV (CA IV): A Personal and Historical Perspective.- Carbonic Anhydrase Expression in Kidney and Renal Cancer: Implications for Diagnosis and Treatment -- Carbonic Anhydrase IX: Regulation and Role in Cancer.- Carbonic Anhydrase IX as an Imaging and Therapeutic Target for Tumors and Metastases -- Carbonic Anhydrase IX (CAIX) as a Mediator of Hypoxia-induced Stress Response in Cancer Cells -- Carbonic Anhydrases and Brain pH in the Control of Neruronal Excitability -- Carbonic Anhydrase Inhibitors: Drug Design -- Natural Products that Inhibit Carbonic Anhydrases -- Glaucoma and the Application of Carbonic Anhydrase Inhibitors -- Carbonic Anhydrase Inhibitors and High Altitude Illnesses -- Thermal-Stable Carbonic Anhydrases: A Structural Overview -- Carbonic Anhydrases in Industrial Applications. Index. |
Record Nr. | UNINA-9910298313303321 |
Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Centromeres and Kinetochores : Discovering the Molecular Mechanisms Underlying Chromosome Inheritance / / edited by Ben E. Black |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XI, 554 p. 101 illus., 98 illus. in color.) |
Disciplina | 571.844 |
Collana | Progress in Molecular and Subcellular Biology |
Soggetto topico |
Cytology - Technique
Cytology Medical genetics Cytological Techniques Cell Biology Medical Genetics |
ISBN |
3319585924
9783319585925 3319585916 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Preface -- Use of Mass Spectrometry to Study the Centromere and Kinetochore -- Critical Foundation of the Kinetochore: the Constitutive Centromere Associated Network (CCAN) -- The Power of Xenopus Egg Extract for Reconstitution of Centromere and Kinetochore Function -- Centrochromatin of Fungi -- Evolutionary Lessons from Species with Unique Kinetochores.-Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis -- Orchestrating the Specific Assembly of Centromeric Nucleosomes -- Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishment -- Post-translational Modifications of Centromeric Chromatin -- Centromere Silencing Mechanisms -- Centromere Transcription: Means and Motive -- The Promises and Challenges of Genomic Studies of Human Centromeres -- DNA Sequences in Centromere Formation and Function -- The Unique DNA Sequences Underlying Equine Centromeres -- Centromere Dynamics in Male and Female Germ Cells -- Cell Biology of Cheating—Transmission of Centromeres and Other Selfish Elements Through Asymmetric Meiosis -- Biophysics of Microtubule End Coupling at the Kinetochore -- Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing -- A Kinase-Phosphatase Network That Regulates Kinetochore-Microtubule Attachments and the SAC -- Centromeric Cohesion: Molecular Glue and Much More -- Centromere Structure and Function -- The Role of Centromere Defects in Cancer. |
Record Nr. | UNINA-9910737300203321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Lo trovi qui: Univ. Federico II | ||
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Chemical Biology of Nucleic Acids : Fundamentals and Clinical Applications / / edited by Volker A. Erdmann, Wojciech T. Markiewicz, Jan Barciszewski |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (599 p.) |
Disciplina | 572.8 |
Collana | RNA Technologies |
Soggetto topico |
Biomaterials
Nucleic acids Medicine - Research Biology - Research Medical genetics Nucleic Acid Biomedical Research Medical Genetics |
ISBN | 3-642-54452-5 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | RNA as Major Components in Chemical Evolvable Systems -- How the Early Genetic Code Was Established? - Inference from the Analysis of Extant Animal Mitochondrial Decoding Systems -- Isomerization of RNA Phosphodiester Linkages -- Effects of Ionic Liquid and Liposomes on the Structure, Stability and Function of Nucleic Acids -- Oxidative Damage on RNA Nucleobases -- Use of FRET to Study Dynamics of DNA Replication -- Design, Characterization and Application of Imidazopyridopyrimidine:Naphthyridine Base-Pairing Motifs Consisting of Four Hydrogen Bonds -- Creation of Unnatural Base Pair Systems Toward New DNA/RNA Biotechnologies -- Flexible Nucleobase Analogues. Novel Tools for Exploring the Nucleic Acids -- Sequence Selective Recognition of Double-Stranded RNA -- Determining Transient Nucleic Acid Structures by NMR -- Diastereomer-Specific Repertoire of 7′R- or 7′S-Me-Carba-Locked Nucleic Acids (cLNAs) in Antisense Oligo/RNA Duplexes and Engineering of Physicochemical and Enzymological Properties -- Challenges and Opportunities for Oligonucleotide-Based Therapeutics by Antisense and RNA Interference Mechanisms -- Progress in Chemically Modified Nucleic Acid Aptamers -- Aptamers as Molecular Smugglers -- Biochemical Aspects of Subcellular RNA Transport and Localization -- Small Size, Big Impact: Bacterial Functional Nucleic Acids and Their Applications -- Towards Defined DNA and RNA Delivery Vehicles Using Nucleic Acid Nanotechnology -- Targeted Editing of Therapeutic Genes Using DNA-Based Transcriptional Activators: Scope and Challenges -- Interaction of DNA Intramolecular Structures with Their Complementary Strands: A Thermodynamic Approach for the Control of Gene Expression -- Site Directed Spin Labelling of RNA for Distance Measurements by EPR -- Chemo-Enzymatic Strategies to Modify RNA in vitro or in Living Cells -- Metal Dependence of Ligand Binding and Heavy-Atom Derivatization of Evolutionarily Distinct PreQ1 Riboswitches -- DNA G-Quadruplexes and I-Motifs in Therapeutics and Diagnostics -- Peptides Targeting G-Quadruplex Structures -- Synthesis of Site-Specifically Modified Long-Mer RNAs -- Synthesis and Exon-Skipping Activity of Chemically-Modified RNAs -- mRNA and snRNA Cap Analogs: Synthesis and Applications -- Innovative Chemistry for Synthesis of Regular RNA, 5’-Triphosphate RNA or 5’-Capped RNA. |
Record Nr. | UNINA-9910298309903321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways / / edited by Silke Rickert-Sperling, Robert G. Kelly, Nikolaus Haas |
Edizione | [2nd ed. 2024.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 |
Descrizione fisica | 1 online resource (1098 pages) |
Disciplina | 616.12043 |
Collana | Advances in Experimental Medicine and Biology |
Soggetto topico |
Medical genetics
Medicine - Research Biology - Research Cardiology Medicine Medical Genetics Biomedical Research Clinical Medicine |
ISBN |
9783031440878
9783031440861 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Section I: General introduction in cardiac development -- Section II: Different chapters covering the different types of congenital heart disease -- Section III: The overall perspective. |
Record Nr. | UNINA-9910865241003321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024 | ||
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Lo trovi qui: Univ. Federico II | ||
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Congenital Heart Diseases: The Broken Heart : Clinical Features, Human Genetics and Molecular Pathways / / edited by Silke Rickert-Sperling, Robert G. Kelly, David J. Driscoll |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Vienna : , : Springer Vienna : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (745 p.) |
Disciplina | 610 |
Soggetto topico |
Medicine - Research
Biology - Research Cardiology Developmental biology Medical genetics Biomedical Research Developmental Biology and Stem Cells Medical Genetics |
ISBN | 3-7091-1883-2 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Section I: General introduction in cardiac development -- Section II: Different chapters covering the different types of congenital heart disease -- Section III: The overall perspective. |
Record Nr. | UNINA-9910253880503321 |
Vienna : , : Springer Vienna : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cultural Phylogenetics : Concepts and Applications in Archaeology / / edited by Larissa Mendoza Straffon |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (208 p.) |
Disciplina | 930.1 |
Collana | Interdisciplinary Evolution Research |
Soggetto topico |
Evolution (Biology)
Medical genetics Anthropology Biology - Philosophy Archaeology Evolutionary Biology Medical Genetics Philosophy of Biology |
ISBN | 3-319-25928-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 2.1 Skateboard Decks |
Record Nr. | UNINA-9910253871103321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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Disordered Vertebral and Rib Morphology in Pudgy Mice : Structural Relationships to Human Congenital Scoliosis / / by Frederic Shapiro |
Autore | Shapiro Frederic |
Edizione | [1st ed. 2016.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 |
Descrizione fisica | 1 online resource (IX, 123 p. 20 illus., 15 illus. in color.) |
Disciplina | 617.375 |
Collana | Advances in Anatomy, Embryology and Cell Biology |
Soggetto topico |
Medical genetics
Anatomy, Comparative Biology - Technique Medical Genetics Animal Anatomy Experimental Organisms |
ISBN | 3-319-43151-X |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | I. INTRODUCTION -- II. MATERIALS AND METHODS -- 1. Source, distribution, and ages of pudgy and non-affected mice. - 2. Whole mount preparations -- 3. Radiographic studies -- 4. Histologic studies -- 5. Computerized three-dimensional reconstructions -- 6. Previous studies on chick vertebral development and human congenital scoliosis -- III. RESULTS -- 1. Gross appearance -- 2. Whole mount appearances -- 3. Radiographic studies -- 4. Histology studies: vertebrae, ribs, intervertebral discs and ganglia -- 5. Computerized three-dimensional reconstructions -- 6. Chick embryo vertebral development -- 7. Radiology and histopathology of human congenital scoliosis spine -- IV. DISCUSSION -- ion -- 3. The pudgy mouse -- 4. Genetic influences on axial development; mutations identified in mouse models with vertebral deformation -- 5. Congenital scoliosis (human); its similarity with pudgy mouse vertebral abnormalities -- 6. Pathogenesis of pudgy and human congenital scoliosis based on histopathologic studies.-V. CONCLUSIONS -- 1. Implications of pudgy vertebral abnormalities for biologic research -- 2. Implications of pudgy vertebral abnormalities for clinical patient treatment. . |
Record Nr. | UNINA-9910254543003321 |
Shapiro Frederic
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2016 | ||
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Lo trovi qui: Univ. Federico II | ||
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