Chemogenomics in drug discovery [[electronic resource] ] : a medicinal chemistry perspective / / edited by Hugo Kubinyi and Gerhard Müller |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (489 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
KubinyiHugo
MüllerGerhard <1963-> |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Pharmaceutical chemistry
Drug development Médicaments - Développement Chimie pharmaceutique Médicaments - Recherche Médicaments - Conception |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-51949-5
9786610519491 3-527-60394-8 3-527-60402-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Target family-directed masterkeyes in chemogenomics / Gehard Müller -- Drug discovery from side effects / Hugo Kubinyi -- The value of chemical genetics in drug discovery / Keith Russell and William F. Michne -- Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther -- The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri -- Structural aspects of kinases and their inhibitors / Rogier Buijsman -- A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus -- Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb -- Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche -- Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider -- Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann -- Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya. |
Record Nr. | UNINA-9910144276003321 |
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chemogenomics in drug discovery [[electronic resource] ] : a medicinal chemistry perspective / / edited by Hugo Kubinyi and Gerhard Müller |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (489 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
KubinyiHugo
MüllerGerhard <1963-> |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Pharmaceutical chemistry
Drug development Médicaments - Développement Chimie pharmaceutique Médicaments - Recherche Médicaments - Conception |
ISBN |
1-280-51949-5
9786610519491 3-527-60394-8 3-527-60402-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Target family-directed masterkeyes in chemogenomics / Gehard Müller -- Drug discovery from side effects / Hugo Kubinyi -- The value of chemical genetics in drug discovery / Keith Russell and William F. Michne -- Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther -- The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri -- Structural aspects of kinases and their inhibitors / Rogier Buijsman -- A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus -- Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb -- Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche -- Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider -- Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann -- Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya. |
Record Nr. | UNINA-9910830617603321 |
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chemogenomics in drug discovery [[electronic resource] ] : a medicinal chemistry perspective / / edited by Hugo Kubinyi and Gerhard Müller |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2004 |
Descrizione fisica | 1 online resource (489 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
KubinyiHugo
MüllerGerhard <1963-> |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Pharmaceutical chemistry
Drug development Médicaments - Développement Chimie pharmaceutique Médicaments - Recherche Médicaments - Conception |
ISBN |
1-280-51949-5
9786610519491 3-527-60394-8 3-527-60402-2 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Target family-directed masterkeyes in chemogenomics / Gehard Müller -- Drug discovery from side effects / Hugo Kubinyi -- The value of chemical genetics in drug discovery / Keith Russell and William F. Michne -- Structural aspects of binding site similarity: a 3D upgrade for chemogenomics / Andreas Bergner and Judith Günther -- The contribution of molecular informatics to chemogenomics: knowledge-based discovery of biological targets and chemical lead compounds / Edgar Jacoby, Ansgar Schuffenhauer, and Pierre Acklin -- Chemical kinomics / Bert M. Klebl, Henrik Daub, and György Kéri -- Structural aspects of kinases and their inhibitors / Rogier Buijsman -- A chemical genomics approach for ion channel modulators / Karl-Heinz Baringhaus and Gerhard Hessler -- Phosphodiesterase inhibitors: a chemogenomic view / Martin Hendrix and Christopher Kallus -- Proteochemometrics: a tool for modeling the molecular interaction space / Jarl E.S. Wikberg, Maris Lapinsch, and Peteris Prusis -- Some principles related to chemogenomics in compound library and template design for GPCRs / Thomas R. Webb -- Computational filters in lead generation: targeting drug-like chemotypes / Wolfgang Guba and Olivier Roche -- Navigation in chemical space: ligand-based design of focused compound libraries / Gisbert Schneider and Petra Schneider -- Natural product-derived compound libraries and protein structure similarity as guiding principles for the discovery of drug candidates / Marcus A. Koch and Herbert Waldmann -- Combinatorial chemistry in the age of chemical genomics / Reni Joseph and Prabhat Arya. |
Record Nr. | UNINA-9910840919103321 |
Weinheim, : Wiley-VCH, c2004 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
Descrizione fisica | 1 online resource (373 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
Soggetto genere / forma | Electronic books. |
Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
Record Nr. | UNINA-9910144273203321 |
Weinheim, : Wiley-VCH, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
Descrizione fisica | 1 online resource (373 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
Record Nr. | UNINA-9910830465203321 |
Weinheim, : Wiley-VCH, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
Descrizione fisica | 1 online resource (373 p.) |
Disciplina | 615.19 |
Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
Collana | Methods and principles in medicinal chemistry |
Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
Record Nr. | UNINA-9910840775703321 |
Weinheim, : Wiley-VCH, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|