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Endocrinology and systemic diseases / / edited by Piero Portincasa, Gema uÌhbeck, Hendrik M. Nathoe
| Endocrinology and systemic diseases / / edited by Piero Portincasa, Gema uÌhbeck, Hendrik M. Nathoe |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (48 illus., 42 illus. in color. eReference.) |
| Disciplina | 616.4 |
| Collana | Endocrinology |
| Soggetto topico |
Internal medicine
Cardiology Endocrine glands - Diseases Glàndules endocrines Medicina interna Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-319-68729-8 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Impact of endocrine disorders on typical and atypical cardiovascular risk factors -- Impact of endocrine disorders on blood pressure -- Impact of endocrine disorders on the heart -- Impact of endocrine disorders on vasculature -- Impact of endocrine disorders on the kidney -- Impact of endocrine disorders on the liver -- Impact of endocrine disorders on gastro-intestinal diseases -- Impact of endocrine disorders on autoimmune diseases -- Neuroendocrine involvement in immune mediated rheumatic diseases -- Impact of endocrine disorders on hematologic diseases -- Impact of endocrine disorders on skin disorders -- Endocrine disorders and neurologic manifestations -- Endocrine disorders and psychiatric manifestations -- Impact of endocrine disorders in the critically ill -- Impact of endocrine disorders in the elderly. . |
| Record Nr. | UNINA-9910483181703321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Famous Composers – Diseases Reloaded / / by Andreas Otte
| Famous Composers – Diseases Reloaded / / by Andreas Otte |
| Autore | Otte Andreas |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (180 pages) |
| Disciplina | 780.922 |
| Soggetto topico |
Medical jurisprudence
Music - History and criticism Music Forensic Medicine History of Music Classical Music Compositors Història de la medicina Malalties |
| Soggetto genere / forma |
Biografies
Llibres electrònics |
| ISBN |
9783031066719
9783031066702 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introductory to the Topic -- Johann Sebastian Bach (1685–1750) -- Domenico Scarlatti (1685–1757) -- Nicolò Paganini (1782–1840) -- Francisco Tárrega (1852–1909) -- Maurice Ravel (1875–1937) -- Heitor Villa-Lobos (1887-1959) -- Robert Schumann (1810-1856). |
| Record Nr. | UNINA-9910595029103321 |
Otte Andreas
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Head & face medicine
| Head & face medicine |
| Pubbl/distr/stampa | [London], : BioMed Central, [2005]- |
| Soggetto topico |
Head - Diseases
Face - Diseases Oral & Maxillofacial Surgery Skull - pathology Face - pathology Head - pathology Cara Cap Malalties |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Periodical Revistes electròniques |
| ISSN | 1746-160X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Head and face medicine |
| Record Nr. | UNINA-9910146226003321 |
| [London], : BioMed Central, [2005]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Heat shock proteins in human diseases / / Alexzander A. A. Asea and Punit Kaur (editors)
| Heat shock proteins in human diseases / / Alexzander A. A. Asea and Punit Kaur (editors) |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (301 pages) : illustrations |
| Disciplina | 572.6 |
| Collana | Heat Shock Proteins |
| Soggetto topico |
Heat shock proteins - Physiological effect
Proteïnes Neuroimmunologia Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-62289-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Preface -- Contents -- About the Editors -- Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and ... -- 1 Introduction -- 2 Cancer, Inflammation and HSP -- 2.1 Role of Inflammation in Cancer Development -- 2.2 Role of Heat Shock Proteins (HSP) in Cancer Development -- 2.3 Relationship Between HSP and Inflammation in Cancer Development -- 3 Role of the Immune System and HSP in Cancer Diagnosis and Prevention -- 3.1 Ingenious Tumour Immune Surveillance Mechanism to Prevent Cancer -- 3.2 HSP as a Biomarker for Cancer Diagnosis -- 3.3 Targeting the HSP-Inflammation Cooperative System as a Target for Cancer Diagnosis Therapeutics -- 3.4 HSP Based Cancer Immunotherapy -- 3.4.1 Vaccines Based on HSP -- 3.4.2 Immune Responses Stimulation Using HSP as an Antigen -- 3.4.3 The Application of HSP as an Adjuvant for the Immune System Stimulation -- 4 Conclusions -- References -- Chaperonin Hsp60 and Cancer Therapies -- 1 Introduction -- 2 Human Hsp60 and Its Bacterial Orthologues -- 2.1 Hsp60 vs. GroEL -- 2.2 Hsp60 and Autoimmune Diseases -- 3 Hsp60 in Carcinogenesis -- 3.1 Chaperonopathy by Mistake -- 3.2 Hsp60 in Cancer -- 4 Hsp60 in Cancer Management -- 4.1 Exosomes: Definition and Biogenesis -- 4.2 Exosomes in Disease: Cancer -- 4.3 Exosomal Hsp60 in Tumorigenesis -- 5 Hsp60 in Cancer Therapy -- 5.1 Hsp and the Immune System -- 5.2 Hsp60-Associated Vaccines in Tumors -- 5.3 Exosomal Hsp60 for Tumor Therapy -- 6 Conclusions -- References -- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment -- 1 Introduction -- 1.1 Heat Shock Proteins in Cancer Cells -- 1.1.1 Intracellular HSP -- 1.1.2 Extracellular HSP in Cancer -- 1.2 Heat Shock Protein Modulation as a Target for Cancer Therapy -- 1.2.1 Targeting Hsp90 -- 1.2.2 Targeting Hsp70.
1.2.3 Targeting Hsp60 in Cancer -- 1.2.4 Targeting Hsp27 in Cancer -- 1.3 Targeted Cancer Thermotherapy -- 1.3.1 Nanoparticles in Cancer Therapy -- 1.3.2 SPIONs -- 1.3.3 Synthesis Approaches -- 1.3.4 Chemical Synthesis: Co-precipitation -- 1.3.5 SPIONs Enhancement: Surface Functionalization -- 1.3.6 Targeting -- 1.3.7 Magnetic Field-Induced Hyperthermia -- 1.4 Combined HSP Targeting with Hyperthermia -- 2 Conclusions -- References -- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Ther... -- 1 Introduction -- 2 HSR Inhibitors Currently in Human Clinical Studies (Table 1 and Fig. 2) -- 2.1 Quercetin -- 2.2 QC12 (Analog Prodrug of Quercetin) -- 2.3 Triptolide -- 2.4 Minnelide (Analog Prodrug of Triptolide) -- 3 HSR Inhibitors Currently in Preclinical Animal Studies (Table 2 and Fig. 3) -- 3.1 PW3405 -- 3.2 Cantharidin -- 3.3 KNK437 -- 3.4 KRIBB11 -- 3.5 Fisetin -- 3.6 Racoglamide A -- 3.7 CCT251236 -- 4 HSR Inhibitors in Early Preclinical Studies (Cancer Cell Lines, Table 3 and Fig. 4) -- 5 Lessons Learned from Preclinical and Clinical Studies -- 5.1 Improvement of Therapeutic Window by Prodrug Design and Nanoparticle Packaging -- 5.2 Combined Application with Chemotherapy Drugs or Drugs against a Different Cancer Target -- 5.3 Target Validation and Use of RNA Aptamer -- 5.4 HSF1 as a Potential Biomarker for Clinical Trial Design and Prognosis Prediction -- 6 Conclusions -- References -- Multifaceted Roles of Heat Shock Factor 1 (HSF 1) in Cancer -- 1 Introduction -- 2 HSF1 Becomes Constitutively Activated Within Cancer Cells -- 2.1 Activation of HSF1 by the Oncogenic RAS Signaling Pathway -- 2.2 Activation of HSF1 by Other Oncogenic Signaling Pathways -- 2.3 Inactivation of HSF1 by Metabolic Stress Signaling -- 2.4 Other Signaling Pathways Suppress HSF1 Through Phosphorylation. 3 HSF1 Enables Oncogenesis Through Multifaceted Mechanisms -- 3.1 Guarding Proteomic Stability in Cancer -- 3.2 Preventing Cell Senescence and Promoting Survival -- 3.3 Contributing to Genomic Instability and Alleviating Genotoxic Stress -- 4 Enhancing Tumor Cell Invasion and Metastasis -- 4.1 Augmenting Critical Oncogenic Signaling Pathways -- 4.2 Reprogramming Cancer Metabolism -- 4.3 Modulating Tumor Immune Evasion -- 4.4 Promoting Oncogenic Growth Non-cell-autonomously -- 5 HSF1 Is a Potential Therapeutic Target and Prognostic Marker -- 6 Conclusions -- References -- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer -- 1 Introduction -- 2 Heat Shock Proteins -- 3 Mode of Action -- 4 HSP27 -- 5 HSP40 -- 6 HSP60 -- 7 HSP70 -- 8 HSP90 -- 9 Differential Expression of Hsp in Gastric Cancer -- 10 HSP70 -- 11 HSP40 -- 12 HSP60 -- 13 Hsp27 -- 14 HSP90 -- 15 Diagnostic and Prognostic Applications of HSP in Gastric Cancer -- 16 HSP70 in H. pylori and EBV Positive Gastric Cancer -- 17 Genetic Polymorphism of HSP70 in Gastric Cancer -- 18 Inhibitors of HSP -- 19 HSP70 Based Vaccines -- 20 Conclusions -- References -- Heat Shock Proteins in Atrial Fibrillation -- 1 Introduction -- 2 HSP and Electrical Remodeling in AF -- 3 HSP and Structural Remodeling in AF -- 4 HSP and Inflammatory Reactions in AF -- 5 HSP and Oxidative Stress in AF -- 6 Clinical Application of HSP -- 7 Conclusions -- References -- Threading Microarrays into Novel Applications -- 1 Introduction -- 1.1 HSP90 as a Stress Marker -- 1.2 HSP90-Oriented Screening of Compound Libraries by the Use of Protein Microarrays (PMA) -- 1.3 Novel Applications by Protein Microarrays (PMA) -- 1.3.1 Quantum Dots as a Sensor for Biomarker -- Studying Mutational Effects by PMA -- 2 Conclusions -- References. Regulation of Kaposi´s Sarcoma-Associated Herpesvirus Biology by Host Molecular Chaperones -- 1 Introduction -- 1.1 KSHV Lifecycle and Biology -- 1.2 KSHV Structure -- 1.3 KSHV Associated Malignancies -- 1.4 KSHV, Protein Folding and Molecular Chaperones -- 1.5 KSHV and Hsp90 -- 1.6 Hsp70 and KSHV -- 1.7 Endoplasmic Reticulum Chaperones and KSHV -- 1.8 KSHV and Nucleophosmin -- 1.9 Putative Candidate KSHV Chaperone Clients Inferred from Proteomics Datasets -- 2 Conclusions -- References -- Role of Heat Shock Factors in Diseases and Immunity -- 1 Introduction -- 1.1 Heat Shock Factors - Functions, Characteristics, Organization and Role in Diseases -- 1.1.1 Heat Shock Response and Importance of HSF -- 1.1.2 Organization and Regulation of HSF -- 1.1.3 PTMs and HSF -- 1.1.4 Importance of Small Molecules in HSF Activation -- 1.1.5 Relationship Between HSF, Diseases and Immunity -- HSF and Cancer -- HSF and Neurodegenerative Diseases -- HSF and Bacterial Infections -- 1.1.6 HSF and Its Turnover Mechanism -- 2 Conclusions -- References -- Heat Shock Proteins and Pain -- 1 Introduction -- 1.1 Inflammation and Pain -- 1.1.1 Pain Signaling -- 1.1.2 Inflammation and Pain -- 1.2 Heat Shock Proteins and Pain -- 1.2.1 Small Heat Shock Proteins(sHsp) -- 1.2.2 Heat Shock Protein 60 (Hsp60) -- 1.2.3 Heat Shock Protein 70 (Hsp70) -- 1.2.4 Heat Shock Protein 90 (Hsp90) -- 1.3 Heat Shock Proteins and Pain Management -- 1.3.1 sHsp -- 1.3.2 Hsp70 -- 1.3.3 Hsp90 -- 2 Conclusions -- References -- HSF1 Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway -- 1 Introduction -- 1.1 Cellular Senescence -- 1.2 Acute Depletion of HSF1 Induces Cellular Senescence -- 1.3 Role of HDIS in Tumorigenesis -- 1.3.1 The DHRS2-MDM2-p53 Pathway -- 1.4 Role of HDIS in Age-Related Pathologies -- 2 Conclusions -- References. Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with Diverse Cellular... -- 1 Introduction -- 1.1 Regulation of Heat Shock Proteins by HSF1 -- 1.2 Functions of Heat Shock Proteins -- 1.3 Characteristics of Intrinsically Unstructured/Disordered Protein (IUP/IDP) -- 1.4 Huntingtin Yeast Two-Hybrid Protein K (HYPK) Is an Intrinsically Unstructured/Disordered Protein (IUP/IDP) -- 1.5 In Vitro and In Vivo Chaperone Activity of HYPK -- 1.6 HYPK Binds with Newly Synthesized Peptides/Proteins -- 1.7 HYPK Interacting Proteins -- 1.8 Chaperones Are in Hub of Protein-Protein Interaction Network -- 1.9 HYPK Is Associated with Aggregate Prone Proteins -- 1.10 Thermal Stress, Hypoxia and Proteasome Inhibitor MG132 Enhance Expression of HYPK in Cultured Cells -- 1.11 HSF1 Binds to the Promoter Sequence of HYPK and Regulates the Expression -- 1.12 HYPK Negatively Regulates Heat Shock Response -- 1.13 HSF1 Also Regulate HYPK Conjoined SERF2 Gene -- 1.14 Functions of HYPK -- 1.15 Does HYPK Modify Expression of Other Genes? -- 1.16 Does HYPK Play Any Role Human Disease? -- 2 Conclusions -- References -- Roles of HSP on Antigen Presentation -- 1 Introduction -- 1.1 Mechanisms of Antigen Presentation by Dendritic Cells -- 1.2 Roles of HSP in Antigen Presentation by MHC-I -- 1.3 Roles of HSP in Antigen Presentation by MHC-II -- 2 Conclusions -- References -- Heat Shock Proteins Mediate Anastasis and Plasticity of Thermotolerant Cells -- 1 Introduction -- 2 Apoptosis -- 2.1 The Role of Mitochondria in Apoptosis -- 2.2 The Role of Death Receptors in Apoptosis -- 3 Thermotolernce and Anastasis -- 4 Role of HSP in Anastasis -- 5 Conclusions and Perspectives -- References -- Index. |
| Record Nr. | UNINA-9910484696803321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Journal of acute disease
| Journal of acute disease |
| Pubbl/distr/stampa | [Amsterdam] : , : Elsevier Science, , [2012]- |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Acute diseases
Acute Disease Malalties |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. Revistes electròniques. |
| ISSN | 2589-5516 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JAD |
| Record Nr. | UNISA-996204496903316 |
| [Amsterdam] : , : Elsevier Science, , [2012]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Lipid Signaling in Human Diseases / / edited by Julian Gomez-Cambronero, Michael A. Frohman
| Lipid Signaling in Human Diseases / / edited by Julian Gomez-Cambronero, Michael A. Frohman |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (xiv, 336 pages) |
| Disciplina | 612.01577 |
| Collana | Handbook of Experimental Pharmacology |
| Soggetto topico |
Pharmacology
Cancer research Medical biochemistry Pharmacology/Toxicology Cancer Research Medical Biochemistry Lípids Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-33668-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1. New Roles for Sphingolipid Signaling and Cell Function -- 1. Role of Sphingosine Kinase 1 and Sphingosine-1-Phosphate Axis in Hepatocellular Carcinoma -- 2. Exploring the Therapeutic Landscape of Sphingomyelinases -- 3. Sphingosine kinases as druggable targets -- Part 2. Phospholipase D and Mitogen Phosphatidic Acid in Human Disease -- 4. Prospects for PLD inhibition in cancer and thrombotic disease -- 5. Phospholipase D and the Mitogen Phosphatidic Acid in Human Disease: Inhibitors of PLD at the Crossroads of Phospholipid Biology and Cancer -- 6. Role of Phospholipase D-Derived Phosphatidic Acid in Regulated Exocytosis and Neurological Disease -- Part 3. Lipid Kinases and Novel Regulatory Pathways -- 7. Diacylglycerol Kinase Malfunction in Human Disease and the Search for Specific Inhibitors -- 8. Functions of Nuclear Polyphosphoinositides -- Part 4. Bioactive Lipids in Health and Disease -- 9. Platelet-Activating Factor as an Effector for Environmental Stressors -- 10. Phospholipase D and Choline Metabolism -- Part 5- Lipids and Membrane Microdomains -- 11. Regulation of Inositol Biosynthesis: Balancing Health and Pathophysiology -- 12. Lipids and Membrane Microdomains: The Glycerolipid and Alkylphosphocholine Class of Cancer Chemotherapeutic Drugs -- Part 6. Nuclear Trafficking of Lipids -- 13. Inositide-Dependent Nuclear Signalling in Health and Disease -- 14. Lipids in Exosome Biology. |
| Record Nr. | UNINA-9910409697903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Neglected tropical diseases Europe and Central Asia / / Peter Steinmann and Jürg Utzinger, editors
| Neglected tropical diseases Europe and Central Asia / / Peter Steinmann and Jürg Utzinger, editors |
| Pubbl/distr/stampa | Cham, Switzerland : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (185 pages) |
| Disciplina | 616.9883 |
| Collana | Neglected tropical diseases (Series) |
| Soggetto topico |
Tropical medicine
Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-84224-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910520063403321 |
| Cham, Switzerland : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Oxidative stress : human diseases and medicine / / Canhua Huang, Yuanyuan Zhang, editors
| Oxidative stress : human diseases and medicine / / Canhua Huang, Yuanyuan Zhang, editors |
| Pubbl/distr/stampa | Gateway East, Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (324 pages) |
| Disciplina | 616.39 |
| Soggetto topico |
Oxidative stress
Estrès oxidatiu Malalties Ciències de la salut |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-16-0522-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910484508003321 |
| Gateway East, Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Peroxisomes: Biogenesis, Function, and Role in Human Disease / / edited by Tsuneo Imanaka, Nobuyuki Shimozawa
| Peroxisomes: Biogenesis, Function, and Role in Human Disease / / edited by Tsuneo Imanaka, Nobuyuki Shimozawa |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (XII, 279 p. 65 illus., 33 illus. in color.) |
| Disciplina | 574.874 |
| Soggetto topico |
Human physiology
Cell biology Cell physiology Bioquímica Human Physiology Cell Biology Cell Physiology Animal Biochemistry Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-15-1169-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part 1 Biogenesis and Function of peroxisome -- 1 The history of peroxisomal research -- 2 Peroxisome Biogenesis -- 3 Peroxisome Degradation and Its Molecular Machinery -- 4 The function of the peroxisome -- Part 2 Dysfunction of Peroxisome and Human Disease -- 5 Peroxisomal disorders -- 6 Model organisms used to understand peroxisomal disorders -- 7 Diagnosis of peroxisomal disorders -- 8 Therapeutic strategies for X-linked adrenoleukodystrophy, a representative peroxisome disease -- Part 3 Topics in Peroxisome Research -- 9 The isolation of peroxisomes -- 10 Structure Biology of peroxisomal proteins, peroxins -- 11 Lipidomics of peroxisomal disorders -- 12 Neurophysiology and neuropsychology for X-ALD. . |
| Record Nr. | UNINA-9910373904003321 |
| Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Proteostasis and Disease : From Basic Mechanisms to Clinics / / edited by Rosa Barrio, James D. Sutherland, Manuel S. Rodriguez
| Proteostasis and Disease : From Basic Mechanisms to Clinics / / edited by Rosa Barrio, James D. Sutherland, Manuel S. Rodriguez |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (350 pages) |
| Disciplina | 572.6 |
| Collana | Advances in Experimental Medicine and Biology |
| Soggetto topico |
Cytology
Neurosciences Immunology Medicine—Research Biology—Research Cancer Cell Biology Neuroscience Biomedical Research Cancer Biology Homeòstasi Proteïnes Immunologia Malalties |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-38266-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inflammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products. |
| Record Nr. | UNINA-9910409697803321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
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