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Lipid rafts and caveolae [[electronic resource] ] : from membrane biophysics to cell biology / / edited by Christopher J. Fielding
| Lipid rafts and caveolae [[electronic resource] ] : from membrane biophysics to cell biology / / edited by Christopher J. Fielding |
| Pubbl/distr/stampa | Weinheim ; ; [Chichester], : Wiley-VCH, 2006 |
| Descrizione fisica | 1 online resource (296 p.) |
| Disciplina | 572.577 |
| Altri autori (Persone) | FieldingChristopher J |
| Soggetto topico |
Cell membranes
Lipids - Physiological effect |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-72277-0
9786610722778 3-527-60807-9 3-527-60750-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Lipid Rafts and Caveolae; Table of Contents; Preface; Author List; 1 Lipid Rafts, Caveolae, and Membrane Traffic; 1.1 Introduction; 1.2 Basic Organization Principles of a Cell Membrane; 1.3 Evidence for Phase Separation in Model Membrane Systems: Liquid-Ordered and Liquid-Disordered Phases; 1.4 Evidence for Phase Separation in Cell Membranes: The "Raft Concept"; 1.5 Raft Domains are Clustered to Exert their Function; 1.6 The Apical Membrane of Epithelial Cells: A Percolating Raft Membrane at 25 °C; 1.7 Caveolae: Scaffolded Membrane Domains Rich in Raft Lipids
1.8 Caveolae and Lipid Rafts in Membrane TrafficAbbreviations; References; 2 The Forces that Shape Caveolae; 2.1 Introduction; 2.2 Physical Modeling of Lipid Membranes; 2.3 Caveolae as Invaginated Lipid Rafts; 2.4 Membrane Inclusions; 2.5 Caveolae as a Thermodynamic Phase Separation of Membrane Proteins; 2.6 Caveolae and Membrane Tension: Mechano-Sensitivity and Mechano-Regulation; 2.7 Conclusions; Abbreviations; References; 3 The Biophysical Characterization of Lipid Rafts; 3.1 Introduction: The Fluid Mosaic Model and Membrane Domains; 3.2 The Origin of the Raft Hypothesis 3.3 The Role of Lipid-Anchored Proteins in the Development of the Membrane Raft Hypothesis3.4 The Case For and Against DRMs as Evidence for "Rafts" in Cell Membranes; 3.5 Why Are Biophysical Studies Useful for Understanding Lipid Rafts?; 3.6 Diffusion-Based Measurements; 3.6.1 Single-Molecule Studies; 3.6.2 Fluorescence Recovery After Photobleaching; 3.6.3 Fluorescence Correlation Spectroscopy; 3.7 Proximity Measurements; 3.7.1 Proximity Measurement Using Homo-FRET; 3.7.2 Proximity Measurement Using Hetero-FRET; 3.8 Conclusions; Abbreviations; References 4 The Role of Caveolae and Noncaveolar Rafts in Endocytosis4.1 Introduction; 4.2 Caveolae are Largely Immobile, Nonendocytic Membrane Domains; 4.3 Caveolae May Show Local, Short-Range Motility: A Role in Transendothelial Transport?; 4.4 An Internalization Wave of Caveolae can be Stimulated by Virus; 4.5 Role of Caveolae in Endocytosis of Cholera Toxin; 4.6 A Small Fraction of Caveolae may become Constitutively Internalized; 4.7 Caveosomes: Intracellular Caveolin-Associated Structures; 4.8 The Role of Dynamin in Caveolar Function; 4.9 Caveolin Immobilizes Rafts/Caveolar Invaginations 4.10 A 2005 Consensus Model for Caveolar EndocytosisAcknowledgments; Abbreviations; References; 5 Role of Cholesterol in Signal Transduction from Caveolae; 5.1 Introduction; 5.2 Lipids of Caveolae; 5.3 Proteins in Caveolae; 5.4 The Caveolin Scaffold Hypothesis; 5.4.1 Does the Scaffold Motif in Signaling Proteins that are Present in Caveolae Represent the Contact Site of these Proteins with Caveolin?; 5.5 FC Binding by Proteins Including Caveolin; 5.6 FC in Caveolae: Effects of Depletion and Loading; 5.7 FC Changes in Caveolae: Effects of Signal Transduction; 5.8 Summary; Abbreviations References |
| Record Nr. | UNINA-9910144556703321 |
| Weinheim ; ; [Chichester], : Wiley-VCH, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Lipid rafts and caveolae [[electronic resource] ] : from membrane biophysics to cell biology / / edited by Christopher J. Fielding
| Lipid rafts and caveolae [[electronic resource] ] : from membrane biophysics to cell biology / / edited by Christopher J. Fielding |
| Pubbl/distr/stampa | Weinheim ; ; [Chichester], : Wiley-VCH, 2006 |
| Descrizione fisica | 1 online resource (296 p.) |
| Disciplina | 572.577 |
| Altri autori (Persone) | FieldingChristopher J |
| Soggetto topico |
Cell membranes
Lipids - Physiological effect |
| ISBN |
1-280-72277-0
9786610722778 3-527-60807-9 3-527-60750-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Lipid Rafts and Caveolae; Table of Contents; Preface; Author List; 1 Lipid Rafts, Caveolae, and Membrane Traffic; 1.1 Introduction; 1.2 Basic Organization Principles of a Cell Membrane; 1.3 Evidence for Phase Separation in Model Membrane Systems: Liquid-Ordered and Liquid-Disordered Phases; 1.4 Evidence for Phase Separation in Cell Membranes: The "Raft Concept"; 1.5 Raft Domains are Clustered to Exert their Function; 1.6 The Apical Membrane of Epithelial Cells: A Percolating Raft Membrane at 25 °C; 1.7 Caveolae: Scaffolded Membrane Domains Rich in Raft Lipids
1.8 Caveolae and Lipid Rafts in Membrane TrafficAbbreviations; References; 2 The Forces that Shape Caveolae; 2.1 Introduction; 2.2 Physical Modeling of Lipid Membranes; 2.3 Caveolae as Invaginated Lipid Rafts; 2.4 Membrane Inclusions; 2.5 Caveolae as a Thermodynamic Phase Separation of Membrane Proteins; 2.6 Caveolae and Membrane Tension: Mechano-Sensitivity and Mechano-Regulation; 2.7 Conclusions; Abbreviations; References; 3 The Biophysical Characterization of Lipid Rafts; 3.1 Introduction: The Fluid Mosaic Model and Membrane Domains; 3.2 The Origin of the Raft Hypothesis 3.3 The Role of Lipid-Anchored Proteins in the Development of the Membrane Raft Hypothesis3.4 The Case For and Against DRMs as Evidence for "Rafts" in Cell Membranes; 3.5 Why Are Biophysical Studies Useful for Understanding Lipid Rafts?; 3.6 Diffusion-Based Measurements; 3.6.1 Single-Molecule Studies; 3.6.2 Fluorescence Recovery After Photobleaching; 3.6.3 Fluorescence Correlation Spectroscopy; 3.7 Proximity Measurements; 3.7.1 Proximity Measurement Using Homo-FRET; 3.7.2 Proximity Measurement Using Hetero-FRET; 3.8 Conclusions; Abbreviations; References 4 The Role of Caveolae and Noncaveolar Rafts in Endocytosis4.1 Introduction; 4.2 Caveolae are Largely Immobile, Nonendocytic Membrane Domains; 4.3 Caveolae May Show Local, Short-Range Motility: A Role in Transendothelial Transport?; 4.4 An Internalization Wave of Caveolae can be Stimulated by Virus; 4.5 Role of Caveolae in Endocytosis of Cholera Toxin; 4.6 A Small Fraction of Caveolae may become Constitutively Internalized; 4.7 Caveosomes: Intracellular Caveolin-Associated Structures; 4.8 The Role of Dynamin in Caveolar Function; 4.9 Caveolin Immobilizes Rafts/Caveolar Invaginations 4.10 A 2005 Consensus Model for Caveolar EndocytosisAcknowledgments; Abbreviations; References; 5 Role of Cholesterol in Signal Transduction from Caveolae; 5.1 Introduction; 5.2 Lipids of Caveolae; 5.3 Proteins in Caveolae; 5.4 The Caveolin Scaffold Hypothesis; 5.4.1 Does the Scaffold Motif in Signaling Proteins that are Present in Caveolae Represent the Contact Site of these Proteins with Caveolin?; 5.5 FC Binding by Proteins Including Caveolin; 5.6 FC in Caveolae: Effects of Depletion and Loading; 5.7 FC Changes in Caveolae: Effects of Signal Transduction; 5.8 Summary; Abbreviations References |
| Record Nr. | UNINA-9910829924103321 |
| Weinheim ; ; [Chichester], : Wiley-VCH, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Lipid rafts and caveolae : from membrane biophysics to cell biology / / edited by Christopher J. Fielding
| Lipid rafts and caveolae : from membrane biophysics to cell biology / / edited by Christopher J. Fielding |
| Pubbl/distr/stampa | Weinheim ; ; [Chichester], : Wiley-VCH, 2006 |
| Descrizione fisica | 1 online resource (296 p.) |
| Disciplina | 571.64 |
| Altri autori (Persone) | FieldingChristopher J |
| Soggetto topico |
Cell membranes
Lipids - Physiological effect |
| ISBN |
9786610722778
9781280722776 1280722770 9783527608072 3527608079 9783527607501 3527607501 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Lipid Rafts and Caveolae; Table of Contents; Preface; Author List; 1 Lipid Rafts, Caveolae, and Membrane Traffic; 1.1 Introduction; 1.2 Basic Organization Principles of a Cell Membrane; 1.3 Evidence for Phase Separation in Model Membrane Systems: Liquid-Ordered and Liquid-Disordered Phases; 1.4 Evidence for Phase Separation in Cell Membranes: The "Raft Concept"; 1.5 Raft Domains are Clustered to Exert their Function; 1.6 The Apical Membrane of Epithelial Cells: A Percolating Raft Membrane at 25 °C; 1.7 Caveolae: Scaffolded Membrane Domains Rich in Raft Lipids
1.8 Caveolae and Lipid Rafts in Membrane TrafficAbbreviations; References; 2 The Forces that Shape Caveolae; 2.1 Introduction; 2.2 Physical Modeling of Lipid Membranes; 2.3 Caveolae as Invaginated Lipid Rafts; 2.4 Membrane Inclusions; 2.5 Caveolae as a Thermodynamic Phase Separation of Membrane Proteins; 2.6 Caveolae and Membrane Tension: Mechano-Sensitivity and Mechano-Regulation; 2.7 Conclusions; Abbreviations; References; 3 The Biophysical Characterization of Lipid Rafts; 3.1 Introduction: The Fluid Mosaic Model and Membrane Domains; 3.2 The Origin of the Raft Hypothesis 3.3 The Role of Lipid-Anchored Proteins in the Development of the Membrane Raft Hypothesis3.4 The Case For and Against DRMs as Evidence for "Rafts" in Cell Membranes; 3.5 Why Are Biophysical Studies Useful for Understanding Lipid Rafts?; 3.6 Diffusion-Based Measurements; 3.6.1 Single-Molecule Studies; 3.6.2 Fluorescence Recovery After Photobleaching; 3.6.3 Fluorescence Correlation Spectroscopy; 3.7 Proximity Measurements; 3.7.1 Proximity Measurement Using Homo-FRET; 3.7.2 Proximity Measurement Using Hetero-FRET; 3.8 Conclusions; Abbreviations; References 4 The Role of Caveolae and Noncaveolar Rafts in Endocytosis4.1 Introduction; 4.2 Caveolae are Largely Immobile, Nonendocytic Membrane Domains; 4.3 Caveolae May Show Local, Short-Range Motility: A Role in Transendothelial Transport?; 4.4 An Internalization Wave of Caveolae can be Stimulated by Virus; 4.5 Role of Caveolae in Endocytosis of Cholera Toxin; 4.6 A Small Fraction of Caveolae may become Constitutively Internalized; 4.7 Caveosomes: Intracellular Caveolin-Associated Structures; 4.8 The Role of Dynamin in Caveolar Function; 4.9 Caveolin Immobilizes Rafts/Caveolar Invaginations 4.10 A 2005 Consensus Model for Caveolar EndocytosisAcknowledgments; Abbreviations; References; 5 Role of Cholesterol in Signal Transduction from Caveolae; 5.1 Introduction; 5.2 Lipids of Caveolae; 5.3 Proteins in Caveolae; 5.4 The Caveolin Scaffold Hypothesis; 5.4.1 Does the Scaffold Motif in Signaling Proteins that are Present in Caveolae Represent the Contact Site of these Proteins with Caveolin?; 5.5 FC Binding by Proteins Including Caveolin; 5.6 FC in Caveolae: Effects of Depletion and Loading; 5.7 FC Changes in Caveolae: Effects of Signal Transduction; 5.8 Summary; Abbreviations References |
| Record Nr. | UNINA-9911019211503321 |
| Weinheim ; ; [Chichester], : Wiley-VCH, 2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nourishing fats : why we need animal fats for health and happiness / / Sally Fallon Morell, foreword by Nina Teicholz
| Nourishing fats : why we need animal fats for health and happiness / / Sally Fallon Morell, foreword by Nina Teicholz |
| Autore | Fallon Sally |
| Pubbl/distr/stampa | New York, New York : , : Grand Central Life & Style, , [2017] |
| Descrizione fisica | 1 online resource (319 pages) |
| Disciplina | 612.397 |
| Soggetto topico |
Lipids - Physiological effect
Lipids - Metabolism Fat - Health aspects Lipids in nutrition |
| ISBN |
1-4555-9256-0
1-4555-7195-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Title Page -- Copyright -- Table of Contents -- Dedication -- Foreword by Nina Teicholz -- Chapter 1: The Greatest Villains -- The campaign to demonize butter and lard promotes industrial fats and oils as free of cholesterol and saturated fat. This pernicious marketing effort, ongoing since 1912, has relied on flimsy evidence to turn Americans away from nutrient-dense animal fats. -- Chapter 2: A Short Lesson on the Biochemistry of Fats -- Saturated, monounsaturated, polyunsaturated-what's the difference? Omega-3, omega-6, omega-9. Fatty acid, triglycerides, cholesterol? What do all these terms mean, and why is the chemistry of fats so important? -- Chapter 3: Not Guilty as Charged -- Animal fats get the blame for everything from cancer to ingrown toenails-and none of these accusations is true! The science shows that saturated animal fats actually protect us from chronic disease. -- Chapter 4: The Many Roles of Saturated Fat -- We need saturated fat for the brain, the heart, the kidneys and the lungs, for hormone production and for protection against inflammation-in fact, for every cell to work properly. Our bodies can't function without saturated fat! -- Chapter 5: AA and DHA -- We get these important fatty acids-which support everything from brain function to gut integrity to healthy skin-exclusively from animal fats. -- Chapter 6: Remember the Activators!: The Fat-Soluble Vitamins A, D and K2 -- Critical vitamins A, D and K2 occur uniquely in animal fats-and Westerners are woefully deficient in these nutrients. The body uses vitamins A, D and K2 for everything from proper vision to growth to fertility. -- Chapter 7: The Rancid and the Trans.
With the revelation that trans fats are bad-bad at any level in the diet-food manufacturers and consumers are using more liquid vegetable oils, but these carry the problem of rancidity. Rancid liquid oils cause uncontrolled reactions on the cellular level -- trans fats inhibit reactions-and both lead to biochemical chaos. -- Chapter 8: Remember the Little Ones: Why Children Need Animal Fats -- Children need animal fats for normal growth and the development of their brains. But at the two-year checkup, doctors warn moms not to give saturated fats to their toddlers, and whole milk is forbidden in school lunches-despite consistent science showing that children on low-fat diets are more likely to suffer from allergies, asthma, learning disorders and obesity. We are literally starving our children in the name of phony science. -- Chapter 9: Animal Fats for the Mind -- The key components of animal fats-stearic acid, AA, cholesterol, and vitamins A, D and K 2-are critical for neurological function and for supporting our emotional biochemistry as well. The receptors for serotonin, the body's feel-good chemical, can't work without cholesterol, and vitamin A helps us focus on completing tasks. It's hard to be happy without plenty of animal fats in the diet. -- Chapter 10: The Queen of Fats: Why Butter Is Better -- The queen of fats, butter is loaded with nutrients the body needs to be healthy and happy. Starve yourself of butter during the day and you'll crave ice cream when nighttime rolls around. Modern processing technologies cannot come close to providing in spreads and margarines the range of vitamins and lipid components present in butter, Nature's fat for optimal growth and development. -- Post Script -- Cholesterol Theory Wipes Out Human Race -- Recipes: Cooking with Nourishing Fats. When you cook with nourishing animal fats, your meals will be satisfying and delicious. -- Acknowledgments -- Other Books by Sally Fallon Morell -- Notes -- Newsletters. |
| Altri titoli varianti | Why we need animal fats for health and happiness |
| Record Nr. | UNINA-9910160305503321 |
Fallon Sally
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| New York, New York : , : Grand Central Life & Style, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
