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Heptinstall's pathology of the kidney
| Heptinstall's pathology of the kidney |
| Edizione | [Seventh edition /] |
| Pubbl/distr/stampa | Philadelphia : , : Wolters Kluwer Health, , [2015] |
| Descrizione fisica | 1 online resource (1539 p.) |
| Disciplina | 616.6/2207 |
| Soggetto topico |
Kidneys - Diseases
Kidneys - Pathophysiology |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-4963-2433-1
1-4698-8755-X 1-4511-4411-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Renal anatomy and histology / Stephen M. Bonsib -- Development of the kidney / Adrian S. Woolf and Dagan Jenkins -- Primer on the pathologic classification and diagnosis of renal disease / J. Charles Jennette, Fred G. Silva, Jean L. Olson, and Vivette D. Dagati -- Cystic diseases and developmental kidney defects / Helen Liapis and Paul Winyard -- The nephrotic syndrome and minimal change disease / Jean L. Olson -- Focal segmental glomerulosclerosis and childhood nephrotic syndrome / Vivette D. DAgati and M. Barry Stokes -- Membranous glomerulonephritis / Glen S. Markowitz and Vivette D. DAgati -- Membranoproliferative glomerulonephritis / Xin J. Zhou and Fred G. Silva -- C3 glomerulopathies, including dense deposit disease / H. Terence Cook and Matthew C. Pickering -- Acute postinfectious glomerulonephritis and glomerulonephritis caused by persistent bacterial infection / Anjali A. Satoskar, Tibor Nadasdy, and Fred G. Silva -- Renal injury associated with human immunodeficiency virus infection and therapy / Arthur H. Cohen and Cynthia C. Nast -- Iga nephropathy and iga vasculitis (henoch-schonlein purpura) nephritis / Mark Haas -- Alports syndrome, familial benign hematuria, nail-patella syndrome, type iii collagen glomerulopathy, and piersons syndrome / Marie-Claire Gubler, Laurence Heidet, and Corinne Antignac -- Renal disease in systemic lupus erythematosus, mixed connective tissue disease, sjögren's syndrome, and rheumatoid arthritis / Vivette D. D'Agati and M. Barry Stokes -- Anti-glomerular basement membrane glomerulonephritis and goodpasture's syndrome / J. Charles Jennette and Volker Nickeleit -- Pauci-immune and antineutrophil cytoplasmic autoantibodymediated crescentic glomerulonephritis and vasculitis / J. Charles Jennette and David B. Thomas -- Volume 2 -- Renal involvement in polyarteritis nodosa, kawasaki disease, takayasu arteritis, and giant cell arteritis / J. Charles Jennette and Harsharan K. Singh -- Thrombotic microangiopathies / Zoltan G. Laszik, Neeraja Kambham, and Fred G. Silva -- Renal disease in pregnancy / Agnes B. Fogo -- Renal disease caused by hypertension / Jean L. Olson -- Diabetic nephropathy / Jean L. Olson and Zoltan G. Laszik -- Renal diseases associated with plasma cell dyscrasias, amyloidoses, and waldenström's macroglobulinemia / Guillermo A. Herrera and Maria M. Picken -- Glomerular diseases with organized deposits / Samy S. Iskandar and Guillermo A. Herrera -- Pyelonephritis, reflux nephropathy, hydronephrosis, and nephrolithiasis / Helen Liapis, Joseph P. Gaut, John E. Tomaszewski, and Lois Arend -- Acute and chronic tubulointerstitial nephritis / Sergey V. Brodsky and Tibor Nadasdy -- Ischemic and toxic acute tubular injury and other ischemic renal injury / Gilbert Moeckel, Michael Kashgarian, and Lorraine V. Racusen -- Renal disease caused by inborn errors of metabolism, storage diseases, and hemoglobinopathies / Laura S. Finn -- Renal changes with aging and end-stage renal disease / Xin J. Zhou, Andrew Fenves, Nosratola D. Vaziri, and Ramesh Saxena -- Renal transplant pathology / Volker Nickeleit, Michael Mengel, and Robert B. Colvin -- Renal neoplasms / John N. Eble and David J. Grignon. |
| Record Nr. | UNINA-9910463772003321 |
| Philadelphia : , : Wolters Kluwer Health, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Heptinstall's pathology of the kidney / / editors, J. Charles Jennette, MD, Kenneth M. Brinckhous Distinguished Professor, Chair of Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Professor of Medicine, division of Nephrology and Hypertension, Executive Director, Division of Nephropathology, University of North Carolina, Chapel Hill, North Carolina, Jean L. Olson, MD, Professor, Director, Renal Pathology and Electron Microscopy, Department of Pathology, University of California San Francisco, San Francisco, California, Fred G. Silva, MD, Nephropathologist, Nephropath, Adjunct Professor of Pathology, University of Arkansas Medical School, Little Rock, Arkansas, Vivette D. D'Agati, MD, Professor of Pathology, Director, Division of Renal Pathology, Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York
| Heptinstall's pathology of the kidney / / editors, J. Charles Jennette, MD, Kenneth M. Brinckhous Distinguished Professor, Chair of Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Professor of Medicine, division of Nephrology and Hypertension, Executive Director, Division of Nephropathology, University of North Carolina, Chapel Hill, North Carolina, Jean L. Olson, MD, Professor, Director, Renal Pathology and Electron Microscopy, Department of Pathology, University of California San Francisco, San Francisco, California, Fred G. Silva, MD, Nephropathologist, Nephropath, Adjunct Professor of Pathology, University of Arkansas Medical School, Little Rock, Arkansas, Vivette D. D'Agati, MD, Professor of Pathology, Director, Division of Renal Pathology, Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York |
| Edizione | [Seventh edition /] |
| Pubbl/distr/stampa | Philadelphia : , : Wolters Kluwer, , [2015] |
| Descrizione fisica | 1 online resource (2 volumes (1592 pages)) : illustrations (chiefly color) |
| Disciplina | 616.6/2207 |
| Collana | Gale eBooks |
| Soggetto topico |
Kidneys - Diseases
Kidneys - Pathophysiology |
| ISBN |
1-4963-2433-1
1-4698-8755-X 1-4511-4411-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Renal anatomy and histology / Stephen M. Bonsib -- Development of the kidney / Adrian S. Woolf and Dagan Jenkins -- Primer on the pathologic classification and diagnosis of renal disease / J. Charles Jennette, Fred G. Silva, Jean L. Olson, and Vivette D. Dagati -- Cystic diseases and developmental kidney defects / Helen Liapis and Paul Winyard -- The nephrotic syndrome and minimal change disease / Jean L. Olson -- Focal segmental glomerulosclerosis and childhood nephrotic syndrome / Vivette D. DAgati and M. Barry Stokes -- Membranous glomerulonephritis / Glen S. Markowitz and Vivette D. DAgati -- Membranoproliferative glomerulonephritis / Xin J. Zhou and Fred G. Silva -- C3 glomerulopathies, including dense deposit disease / H. Terence Cook and Matthew C. Pickering -- Acute postinfectious glomerulonephritis and glomerulonephritis caused by persistent bacterial infection / Anjali A. Satoskar, Tibor Nadasdy, and Fred G. Silva -- Renal injury associated with human immunodeficiency virus infection and therapy / Arthur H. Cohen and Cynthia C. Nast -- Iga nephropathy and iga vasculitis (henoch-schonlein purpura) nephritis / Mark Haas -- Alports syndrome, familial benign hematuria, nail-patella syndrome, type iii collagen glomerulopathy, and piersons syndrome / Marie-Claire Gubler, Laurence Heidet, and Corinne Antignac -- Renal disease in systemic lupus erythematosus, mixed connective tissue disease, sjögren's syndrome, and rheumatoid arthritis / Vivette D. D'Agati and M. Barry Stokes -- Anti-glomerular basement membrane glomerulonephritis and goodpasture's syndrome / J. Charles Jennette and Volker Nickeleit -- Pauci-immune and antineutrophil cytoplasmic autoantibodymediated crescentic glomerulonephritis and vasculitis / J. Charles Jennette and David B. Thomas -- Volume 2 -- Renal involvement in polyarteritis nodosa, kawasaki disease, takayasu arteritis, and giant cell arteritis / J. Charles Jennette and Harsharan K. Singh -- Thrombotic microangiopathies / Zoltan G. Laszik, Neeraja Kambham, and Fred G. Silva -- Renal disease in pregnancy / Agnes B. Fogo -- Renal disease caused by hypertension / Jean L. Olson -- Diabetic nephropathy / Jean L. Olson and Zoltan G. Laszik -- Renal diseases associated with plasma cell dyscrasias, amyloidoses, and waldenström's macroglobulinemia / Guillermo A. Herrera and Maria M. Picken -- Glomerular diseases with organized deposits / Samy S. Iskandar and Guillermo A. Herrera -- Pyelonephritis, reflux nephropathy, hydronephrosis, and nephrolithiasis / Helen Liapis, Joseph P. Gaut, John E. Tomaszewski, and Lois Arend -- Acute and chronic tubulointerstitial nephritis / Sergey V. Brodsky and Tibor Nadasdy -- Ischemic and toxic acute tubular injury and other ischemic renal injury / Gilbert Moeckel, Michael Kashgarian, and Lorraine V. Racusen -- Renal disease caused by inborn errors of metabolism, storage diseases, and hemoglobinopathies / Laura S. Finn -- Renal changes with aging and end-stage renal disease / Xin J. Zhou, Andrew Fenves, Nosratola D. Vaziri, and Ramesh Saxena -- Renal transplant pathology / Volker Nickeleit, Michael Mengel, and Robert B. Colvin -- Renal neoplasms / John N. Eble and David J. Grignon. |
| Altri titoli varianti | Pathology of the kidney |
| Record Nr. | UNINA-9910788251003321 |
| Philadelphia : , : Wolters Kluwer, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Heptinstall's pathology of the kidney / / editors, J. Charles Jennette, MD, Kenneth M. Brinckhous Distinguished Professor, Chair of Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Professor of Medicine, division of Nephrology and Hypertension, Executive Director, Division of Nephropathology, University of North Carolina, Chapel Hill, North Carolina, Jean L. Olson, MD, Professor, Director, Renal Pathology and Electron Microscopy, Department of Pathology, University of California San Francisco, San Francisco, California, Fred G. Silva, MD, Nephropathologist, Nephropath, Adjunct Professor of Pathology, University of Arkansas Medical School, Little Rock, Arkansas, Vivette D. D'Agati, MD, Professor of Pathology, Director, Division of Renal Pathology, Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York
| Heptinstall's pathology of the kidney / / editors, J. Charles Jennette, MD, Kenneth M. Brinckhous Distinguished Professor, Chair of Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Professor of Medicine, division of Nephrology and Hypertension, Executive Director, Division of Nephropathology, University of North Carolina, Chapel Hill, North Carolina, Jean L. Olson, MD, Professor, Director, Renal Pathology and Electron Microscopy, Department of Pathology, University of California San Francisco, San Francisco, California, Fred G. Silva, MD, Nephropathologist, Nephropath, Adjunct Professor of Pathology, University of Arkansas Medical School, Little Rock, Arkansas, Vivette D. D'Agati, MD, Professor of Pathology, Director, Division of Renal Pathology, Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York |
| Edizione | [Seventh edition /] |
| Pubbl/distr/stampa | Philadelphia : , : Wolters Kluwer, , [2015] |
| Descrizione fisica | 1 online resource (2 volumes (1592 pages)) : illustrations (chiefly color) |
| Disciplina | 616.6/2207 |
| Collana | Gale eBooks |
| Soggetto topico |
Kidneys - Diseases
Kidneys - Pathophysiology |
| ISBN |
1-4963-2433-1
1-4698-8755-X 1-4511-4411-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Renal anatomy and histology / Stephen M. Bonsib -- Development of the kidney / Adrian S. Woolf and Dagan Jenkins -- Primer on the pathologic classification and diagnosis of renal disease / J. Charles Jennette, Fred G. Silva, Jean L. Olson, and Vivette D. Dagati -- Cystic diseases and developmental kidney defects / Helen Liapis and Paul Winyard -- The nephrotic syndrome and minimal change disease / Jean L. Olson -- Focal segmental glomerulosclerosis and childhood nephrotic syndrome / Vivette D. DAgati and M. Barry Stokes -- Membranous glomerulonephritis / Glen S. Markowitz and Vivette D. DAgati -- Membranoproliferative glomerulonephritis / Xin J. Zhou and Fred G. Silva -- C3 glomerulopathies, including dense deposit disease / H. Terence Cook and Matthew C. Pickering -- Acute postinfectious glomerulonephritis and glomerulonephritis caused by persistent bacterial infection / Anjali A. Satoskar, Tibor Nadasdy, and Fred G. Silva -- Renal injury associated with human immunodeficiency virus infection and therapy / Arthur H. Cohen and Cynthia C. Nast -- Iga nephropathy and iga vasculitis (henoch-schonlein purpura) nephritis / Mark Haas -- Alports syndrome, familial benign hematuria, nail-patella syndrome, type iii collagen glomerulopathy, and piersons syndrome / Marie-Claire Gubler, Laurence Heidet, and Corinne Antignac -- Renal disease in systemic lupus erythematosus, mixed connective tissue disease, sjögren's syndrome, and rheumatoid arthritis / Vivette D. D'Agati and M. Barry Stokes -- Anti-glomerular basement membrane glomerulonephritis and goodpasture's syndrome / J. Charles Jennette and Volker Nickeleit -- Pauci-immune and antineutrophil cytoplasmic autoantibodymediated crescentic glomerulonephritis and vasculitis / J. Charles Jennette and David B. Thomas -- Volume 2 -- Renal involvement in polyarteritis nodosa, kawasaki disease, takayasu arteritis, and giant cell arteritis / J. Charles Jennette and Harsharan K. Singh -- Thrombotic microangiopathies / Zoltan G. Laszik, Neeraja Kambham, and Fred G. Silva -- Renal disease in pregnancy / Agnes B. Fogo -- Renal disease caused by hypertension / Jean L. Olson -- Diabetic nephropathy / Jean L. Olson and Zoltan G. Laszik -- Renal diseases associated with plasma cell dyscrasias, amyloidoses, and waldenström's macroglobulinemia / Guillermo A. Herrera and Maria M. Picken -- Glomerular diseases with organized deposits / Samy S. Iskandar and Guillermo A. Herrera -- Pyelonephritis, reflux nephropathy, hydronephrosis, and nephrolithiasis / Helen Liapis, Joseph P. Gaut, John E. Tomaszewski, and Lois Arend -- Acute and chronic tubulointerstitial nephritis / Sergey V. Brodsky and Tibor Nadasdy -- Ischemic and toxic acute tubular injury and other ischemic renal injury / Gilbert Moeckel, Michael Kashgarian, and Lorraine V. Racusen -- Renal disease caused by inborn errors of metabolism, storage diseases, and hemoglobinopathies / Laura S. Finn -- Renal changes with aging and end-stage renal disease / Xin J. Zhou, Andrew Fenves, Nosratola D. Vaziri, and Ramesh Saxena -- Renal transplant pathology / Volker Nickeleit, Michael Mengel, and Robert B. Colvin -- Renal neoplasms / John N. Eble and David J. Grignon. |
| Altri titoli varianti | Pathology of the kidney |
| Record Nr. | UNINA-9910807015603321 |
| Philadelphia : , : Wolters Kluwer, , [2015] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The renal system at a glance / / Chris O'Callaghan
| The renal system at a glance / / Chris O'Callaghan |
| Autore | O'Callaghan C. A. |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 |
| Descrizione fisica | 1 online resource (158 pages) : color illustrations |
| Disciplina | 616.6/1 |
| Collana | At a glance series |
| Soggetto topico |
Kidneys - Physiology
Kidneys - Pathophysiology Kidneys - Diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-118-39385-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910466030803321 |
O'Callaghan C. A.
|
||
| Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The renal system at a glance / / Chris O'Callaghan
| The renal system at a glance / / Chris O'Callaghan |
| Autore | O'Callaghan C. A. |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 |
| Descrizione fisica | 1 online resource (158 pages) : color illustrations |
| Disciplina | 616.6/1 |
| Collana | At a glance series |
| Soggetto topico |
Kidneys - Diseases
Kidneys - Pathophysiology Kidneys - Physiology |
| ISBN |
9781118393857
1118393856 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910795823903321 |
|
O'Callaghan C. A.
|
||
| Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The renal system at a glance / / Chris O'Callaghan
| The renal system at a glance / / Chris O'Callaghan |
| Autore | O'Callaghan C. A. |
| Edizione | [Fourth edition.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 |
| Descrizione fisica | 1 online resource (158 pages) : color illustrations |
| Disciplina | 616.6/1 |
| Collana | At a glance series |
| Soggetto topico |
Kidneys - Diseases
Kidneys - Pathophysiology Kidneys - Physiology |
| ISBN |
9781118393857
1118393856 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910808962003321 |
|
O'Callaghan C. A.
|
||
| Chichester, West Sussex ; ; Malden, MA : , : John Wiley & Sons, Incorporated, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Seldin and Giebisch's the kidney [[electronic resource] ] : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan
| Seldin and Giebisch's the kidney [[electronic resource] ] : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan |
| Edizione | [5th ed.] |
| Pubbl/distr/stampa | London, : Academic Press, 2013 |
| Descrizione fisica | 1 online resource (3299 p.) |
| Disciplina | 612.463 |
| Altri autori (Persone) |
AlpernRobert J
MoeOrson W CaplanMichael SeldinDonald W. <1920-> GiebischGerhard H |
| Soggetto topico |
Kidneys - Physiology
Kidneys - Pathophysiology Kidneys - Diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-12-381463-4
1-283-89156-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910463005203321 |
| London, : Academic Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Seldin and Giebisch's the kidney [[electronic resource] ] : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan
| Seldin and Giebisch's the kidney [[electronic resource] ] : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan |
| Edizione | [5th ed.] |
| Pubbl/distr/stampa | London, : Academic Press, 2013 |
| Descrizione fisica | 1 online resource (3299 p.) |
| Disciplina | 612.463 |
| Altri autori (Persone) |
AlpernRobert J
MoeOrson W CaplanMichael SeldinDonald W. <1920-2018> GiebischGerhard H |
| Soggetto topico |
Kidneys - Physiology
Kidneys - Pathophysiology Kidneys - Diseases |
| ISBN |
0-12-381463-4
1-283-89156-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910785905403321 |
| London, : Academic Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Seldin and Giebisch's the kidney : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan
| Seldin and Giebisch's the kidney : physiology and pathophysiology / / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan |
| Edizione | [5th ed.] |
| Pubbl/distr/stampa | London, : Academic Press, 2013 |
| Descrizione fisica | 1 online resource (3299 p.) |
| Disciplina | 612.463 |
| Altri autori (Persone) |
AlpernRobert J
MoeOrson W CaplanMichael SeldinDonald W. <1920-2018.> GiebischGerhard H |
| Soggetto topico |
Kidneys - Physiology
Kidneys - Pathophysiology Kidneys - Diseases |
| ISBN |
0-12-381463-4
1-283-89156-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover -- Seldin and Giebisch's the Kidney -- Copyright Page -- Dedication -- Contents -- Foreword -- Preface -- List of Contributors -- I: Epithelial and Nonepithelial Transport and Regulation -- 1 Epithelial Cell Structure and Polarity -- Introduction -- The Nature and Physiologic Implications of Epithelial Polarity -- Epithelial Cell Structure: Morphology and Physiology -- The Junctional Complex -- The Apical Microvillar Surface -- The Basolateral Plasma Membrane -- The Basement Membrane -- Biogenesis of Epithelial Polarity -- In Vitro Systems -- Polarization Mechanisms: Spatial Cues from Cell Adhesion -- Polarization Mechanisms: The Intrinsic Polarization Machinery -- Sorting Pathways -- Technical Approaches -- Sodium Pump Targeting -- Regulation of Renal Transport Protein Function by Endocytosis and Recycling -- Sorting Signals -- Cell Type-Specific Sorting: Patterns -- Sorting: Mechanisms -- Tyrosine-Based Motifs and Adaptors -- Glycosphingolipid-Rich Membrane Domains -- PDZ Domain-containing Proteins -- Epithelial Cell Polarity and Renal Disease -- Carcinogenesis -- Ischemic Injury -- Genetic Diseases of Proximal Tubule Apical Endocytosis: Dent's Disease and the Oculo Cerebral Renal Syndrome of Lowe -- Polycystic Kidney Disease -- Acknowledgments -- References -- 2 Mechanisms of Ion Transport across Cell Membranes -- Introduction -- The Cell Interior and Extracellular Fluid Have Different Ionic Compositions -- The Plasma Membrane: Structure Related to Function -- The Plasma Membrane is Selectively Permeable -- Mechanisms of ion TRANSPORT -- Ion Transport can be Active or Passive -- Active and Passive Transport Processes can be Evaluated by Considering Direction of Electrochemical Potential Difference (D... -- Pathways and Mechanisms of Passive Transport -- Diffusion and Electrodiffusion -- Electrodiffusion -- Mediated Transport.
Thermodynamics of Mediated Passive Transport -- Kinetics of Mediated Passive Transport -- Modes of Coupled Transport -- Pathways and Mechanisms of Active Transport -- Primary Active Transport -- Secondary Active Transport -- Ion Transport PROTEINS -- Pores -- Channels -- K+-Selective Channels -- Na+-Selective Channels -- Cl− Selective Channels -- Carriers -- Pumps -- Similarities and Differences between Ion Transport Proteins -- References -- 3 Renal Ion-Translocating ATPases -- P-ATPases -- Structure and Function of Ca2+-ATPases (SERCA and PMCA) -- Structure of Na,K-ATPase and H,K-ATPase -- Catalytic α-Subunit -- Structure -- Isoforms -- β-Subunit -- Isoforms -- Structure and α-β Interaction -- Functional Role -- FXYD Proteins -- Isoforms -- Function and Interaction with α- and β-Subunits -- Properties of Na,K-ATPase and H,K-ATPase -- Ion Transport -- Pharmacology -- Genetics -- Regulation of Na,K-ATPase -- Substrates -- Post-Translational Modifications -- Synthesis and Degradation -- Membrane Trafficking -- Interaction with the Cytoskeleton -- New Physiological Functions of Na,k-ATPase -- Cell Signaling by Na,K-ATPase -- Role of Na,K-ATPase in Cell Adhesion -- Na,K-ATPase in the Kidney -- Regulation of Na,K-ATPase in Proximal Tubule -- Control of Na,K-ATPase by Insulin -- Control of Na,K-ATPase by Dopamine and Parathormone -- Angiotensin II Exerts a Biphasic Effect on Na,K-ATPase -- Regulation of Na,K-ATPase in Thick Ascending Limb of Henle's Loop -- Control of Na,K-ATPase in Collecting Duct -- Aldosterone Induces a Biphasic Stimulation of Na,K-ATPase -- Vasopressin Stimulates Na,K-ATPase -- Na,K-ATPase Expression is Regulated by Sodium Availability -- Induction of Na,K-ATPase is Associated with Sodium Retention in Nephrotic Syndrome and Liver Cirrhosis -- H,K-ATPases in Kidney -- Gastric H,K-ATPase -- Colonic H,K-ATPase -- V-ATPase. Structure and Mechanism of Action of V-ATPases -- Isoforms -- Renal Isoforms of the V-ATPase -- Multiple Functions of the V-ATPASE in the Kidney -- Expression in the Kidney -- Bicarbonate Absorption -- Role of the V-ATPase in Intercalated Cells -- Role of the V-ATPase in Endocytosis in Renal Epithelial Cells -- References -- 4 Mechanisms of Water Transport Across Cell Membranes and Epithelia -- Introduction -- Basic Principles -- Osmotic Equilibrium is a Balance of Osmotic and Hydrostatic Forces -- Osmotic Water Flows Across Lipid and Porous Membranes have Different Properties -- Osmotic Water Flow Across Lipid Membranes -- Osmotic Water Flow Across a Porous Membrane -- Large Pores -- Single-File Pore -- Comparison of Diffusion and Osmotic Permeability Coefficients Reveals Whether Water Permeates Lipid Bilayer or Pores -- Porous Membrane -- Unstirred Layers are a Major Source of Artifacts in Water Permeability Measurements -- Unstirred-Layer Effects on Measurement of Pdw -- Unstirred-Layer Effects on the Measurement of Pos -- Solute Reflection Coefficients Denote Effective Osmolality of a Solution vis-à-vis a Membrane -- Lipid Membrane -- Porous Membrane -- Solvent Drag Can Account for Uphill Solute Transport -- Water Transport Across the Cell Membrane -- Intracellular Water Behaves Similar to Water in Free Solution -- The Osmotic Behavior of Cells is not Ideal -- Net Water Transport Across Membranes of Animal Cells is Osmotic -- Cell Volume is Determined by the Amount of Cell Solute and the Extracellular Osmolality -- Water Permeability of the Plasma Membrane Varies Considerably Among Cell Types -- Pathways for Water Transport Across Cell Membranes -- Water Pores Determine High Cell-Membrane Water Permeability -- High POS/Pd -- Low Arrhenius Activation Energy -- Sensitivity to Hg -- Flux Interactions -- Cell Membrane Water Pores are Aquaporins. Mechanism of Water Permeation in AQPs -- Certain Aquaporins are Permeable to Solutes and Perhaps to Physiologic Gases -- Regulation of AQP-Mediated Water Permeability -- Other Membrane Proteins May Contribute to Water Transport -- Do Co-Transporters Perform Active Water Transport? -- Summary and Conclusions -- Water Transport in Epithelia -- Characteristics of Transepithelial Water Transport -- Epithelia Have Very Different Water Permeabilities -- Two Types of Transepithelial Water Transport -- Solute-Solvent Coupling -- Three-Compartment Models Define the Problem -- Standing-Gradient Hypothesis Explains Near-Isosmotic Fluid Transport, but is Difficult to Reconcile with Current Experiment... -- Near-Isosmotic Fluid Transport Model Solves the Difficulties of Three-Compartment Models -- Solute Recirculation in the Paracellular Pathway in Theory Explains Truly Isosmotic Transepithelial Fluid Transport -- In Certain Epithelia Asymmetries in Solute Composition Play Significant Roles -- Pathways for Transepithelial Water Transport are also Controversial -- Transcellular Osmotic Water Transport is Supported by High Cell-Membrane Pos -- Paracellular Osmotic Water Transport is Supported by Indirect Arguments -- Summary and Conclusions -- References -- 5 Cell Volume Control -- Cell Volume Regulatory Mechanisms -- Cell Volume Regulatory Ion Transport -- Ions in Cell Volume Maintenance -- Ion Release Following Cell Swelling -- Ion Uptake upon Cell Shrinkage -- Osmolytes -- Osmolyte Accumulation by Metabolism -- Osmolyte Accumulation by Transport -- Osmolyte Release -- Metabolic Pathways Sensitive to Cell Volume -- Protein and Glycogen Metabolism -- Glucose and Amino Acid Metabolism -- Oxidative Metabolism -- Other Metabolic Pathways -- Cell Volume-Sensitive Genes -- Signaling of Cell Volume Regulation -- Intracellular Ca2+ -- Cytoskeleton. Protein Phosphorylation -- Phosphatidylinositol 4,5,-Bisphosphate -- Phospholipase A2 and Eicosanoids -- pH of Acidic Cellular Compartments -- Others -- Challenges and functions affecting cell Volume -- Alterations of Extracellular Fluid Osmolarity and Composition -- Osmolarity -- Extracellular K+ Concentration -- H+ and HCO3− Concentration -- Organic Acids -- Urea, Drugs, and Toxins -- Functional States Affecting Cell Volume Control -- Energy Depletion -- Transport -- Influence of Hormones and Transmitters on Cell Volume -- Neuromuscular Excitability -- Metabolism -- Cell Proliferation -- Migration -- Apoptotic Cell Death -- Necrotic Cell Death -- References -- 6 Solute Transport, Energy Consumption, and Production in the Kidney -- Introduction -- Energy Consumption -- Na Transport and Energy Consumption in the Kidney -- Na+ Transport and O2 Consumption -- Heterogeneity in Na+ Transport Efficiency among Nephron Segments -- Proximal Tubule -- Thick Ascending Limb of Henle -- CCD -- Energy Cost of Primary Active Transport -- P-type-ATPases -- Na+,K+-ATPase -- Ca2+-ATPase -- H+,K+-ATPase -- V-type ATPases -- ABC Superfamily -- Comparison of Ion Transporting ATPase Activities and QO2 along the Nephron -- Metabolic Basis in the Kidney -- Energy Production Pathway in the Kidney -- Mitochondrial Oxidative Phosphorylation -- Tricarboxylic Acid Cycle -- β-Oxidation of Fatty Acids -- Ketone Body Metabolism -- Glycolysis -- Gluconeogenesis -- Metabolic Parameters along Nephron Segments -- Preference of Metabolic Substrates in Nephron Segments -- Substrate Preference Along the Nephron Segments -- Proximal Tubule (PT) -- Thin Descending Limb of the Loop of Henle (TDL) -- Cortical Thick Ascending Limb of the Loop of Henle (CTAL) -- Medullary Thick Ascending Limb of the Loop of Henle (MTAL) -- Distal Convoluted Tubule (DCT) -- Cortical Collecting Duct (CCD). Outer Medullary Collecting Duct (OMCD). |
| Record Nr. | UNINA-9910965112903321 |
| London, : Academic Press, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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