Bacterial Ion Channels and Their Eukaryotic Homologs / / edited by Andrzej Kubalski, Boris Martinac |
Pubbl/distr/stampa | Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014 |
Descrizione fisica | 1 online resource (xx, 321 pages) : illustrations |
Disciplina | 571.64293 |
Soggetto topico |
Bacterial cell walls
Ion channels |
ISBN | 1-68367-195-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | K+ channels : a survey and a case study of Kch of Escherichia coli / Mario Meng-Chiang Kuo, Ching Kung, and Yoshiro Saimi -- The Ktn domain and its role as a channel and transporter regulator / Ian R. Booth [and others] -- Deciphering Streptomyces lividans KcsA as a K channel model / Hildgund Schrempf -- The molecular basis of K+ channel gating / Christopher P. Ptak, Yi-Shiuan Liu, and Eduardo Perozo -- Glutamate-activated channels / Indira H. Shrivastava and H. Robert Guy -- Voltage-gated K+ channels / H. Robert Guy and Indira H. Shrivastava -- Inward rectifier K+ channels / Indira H. Shrivastava and H. Robert Guy. From prokaryotes to eukaryotes : molecular modeling and simulation studies of ion channels / Philip C. Biggin, Alessandro Grottesi, and Mark S.P. Sansom -- Towards an understanding of membrane channels / Emad Tajkhorshid [and others] -- Bacterial Na channels : progenitors, progeny, or parallel evolution? / Evgeny Pavlov [and others] -- The CLC family of proteins : chloride transporters and channels / Heather R. Rickard [and others] -- The bacterial mechanosensitive channel MscS and its extended family / Paul Blount [and others] -- MscL, a bacterial mechanosensitive channel / Sergei Sukharev [and others] -- The role of bacterial channels in cell physiology / Ian R. Booth [and others]. |
Record Nr. | UNINA-9910830270303321 |
Washington, District of Columbia : , : John Wiley & Sons, Inc., , 2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Channels |
Pubbl/distr/stampa | Austin, Tex., : Landes Bioscience, 2007- |
Disciplina | 571.6 |
Soggetto topico |
Ion channels
Ion Channels |
Soggetto genere / forma | Periodical |
ISSN | 1933-6969 |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNISA-996201357303316 |
Austin, Tex., : Landes Bioscience, 2007- | ||
Materiale a stampa | ||
Lo trovi qui: Univ. di Salerno | ||
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Channels |
Pubbl/distr/stampa | Austin, Tex., : Landes Bioscience, 2007- |
Disciplina | 571.6 |
Soggetto topico |
Ion channels
Ion Channels |
Soggetto genere / forma | Periodical |
ISSN | 1933-6969 |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910142312903321 |
Austin, Tex., : Landes Bioscience, 2007- | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Comparative aspects of mechanoreceptor systems / guest editor: F. Ito ; with contributions by J. Adler ... [et al.] |
Pubbl/distr/stampa | Berlin ; New York : Springer-Verlag, c1992 |
Descrizione fisica | xiii, 309 p. : ill. ; 25 cm |
Disciplina | 591.18 |
Altri autori (Persone) | Ito, Fumi |
Collana | Advances in comparative and environmental physiology ; 10 |
Soggetto topico |
Mechanoreceptors
Comparative physiology Ion channels |
ISBN | 3540541187 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNISALENTO-991001500969707536 |
Berlin ; New York : Springer-Verlag, c1992 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. del Salento | ||
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Endolysosomal voltage-dependent cation channels / / edited by Christian Wahl-Schott and Martin Biel |
Edizione | [1st ed. 2023.] |
Pubbl/distr/stampa | Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] |
Descrizione fisica | 1 online resource (310 pages) |
Disciplina | 571.64 |
Collana | Handbook of Experimental Pharmacology |
Soggetto topico |
Endosomes
Ion channels Lysosomes |
ISBN |
9783031315237
9783031315220 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I: Physiological Functions of Endo-lysosomal Cation Channels -- NAADP-Mediated Ca2+ Signalling -- NAADP-Dependent TPC Current -- NAADP-Evoked Ca2+ Signaling: The DUOX2–HN1L/JPT2–Ryanodine Receptor 1 Axis -- TPC Functions in the Immune System -- Lysosomal Ion Channels and Lysosome– 1 Organelle Interactions -- TRPML1 and TFEB, an Intimate Affair -- Lysosomal Potassium Channels -- Part II Structure and Composition of TPC and TRPML Channels -- Structure and Function of Plant and Mammalian TPC Channels -- A Structural Overview of TRPML1 and the TRPML Family -- Endo-Lysosomal Two-Pore Channels and Their Protein Partners -- Part III: Tools and Methods to Characterize Endolysosomal Cation Channels -- Electrophysiological Techniques on the Study of Endolysosomal Ion Channels -- The Plant Vacuole as Heterologous System to Characterize the Functional Properties of TPC Channels -- Expanding the Toolbox: Novel Modulators of Endolysosomal Cation Channels -- Characterization of Endo-Lysosomal Cation Channels Using Calcium Imaging. |
Record Nr. | UNINA-9910720075603321 |
Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Epithelial anion transport in health and disease [[electronic resource] ] : the role of the SLC26 transporters family |
Pubbl/distr/stampa | Chichester, U.K., : John Wiley & Sons, 2006 |
Descrizione fisica | 1 online resource (285 p.) |
Disciplina |
571.55364
616.042 |
Collana | Novartis Foundation Symposium |
Soggetto topico |
Epithelial cells
Carrier proteins Ion channels |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-51891-X
9786610518913 0-470-02957-9 0-470-02956-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Chair's introduction; Overview of the SLC26 family and associated diseases; Discussion; Individual characteristics of members of the SLC26 family in vertebrates and their homologues in insects; Discussion; Sulfate transport by SLC26 transporters; Discussion; Sugar transport by members of the SLC26 superfamily; Discussion; SLC26A3 and congenital chloride diarrhoea; Discussion; Expression, regulation and the role of SLC26 C1/HCO exchangers in kidney and gastrointestinal tract; Discussion
Anion exchangers in flux: functional differences between human and mouse SLC26A6 polypeptidesDiscussion; Physiology of electrogenic SLC26 paralogues; Discussion; Role of SLC26-mediated C1/base exchange in proximal tubule NaCl transport; Discussion; SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion; Discussion; Regulatory interaction between CFTR and the SLC26 transporters; Discussion; Insights from a transgenic mouse model on the role of SLC26A2 in health and disease; Discussion New insights into the role of pendrin (SLC26A4) in inner ear fluid homeostasisDiscussion; The renal physiology of pendrin (SLC26A4) and its role in hypertension; Discussion; Interaction of prestin (SLC26A5) with monovalent intracellular anions; Discussion; Final discussion; Index of contributors; Subject index |
Record Nr. | UNINA-9910143720003321 |
Chichester, U.K., : John Wiley & Sons, 2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Epithelial anion transport in health and disease [[electronic resource] ] : the role of the SLC26 transporters family |
Pubbl/distr/stampa | Chichester, U.K., : John Wiley & Sons, 2006 |
Descrizione fisica | 1 online resource (285 p.) |
Disciplina |
571.55364
616.042 |
Collana | Novartis Foundation Symposium |
Soggetto topico |
Epithelial cells
Carrier proteins Ion channels |
ISBN |
1-280-51891-X
9786610518913 0-470-02957-9 0-470-02956-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Chair's introduction; Overview of the SLC26 family and associated diseases; Discussion; Individual characteristics of members of the SLC26 family in vertebrates and their homologues in insects; Discussion; Sulfate transport by SLC26 transporters; Discussion; Sugar transport by members of the SLC26 superfamily; Discussion; SLC26A3 and congenital chloride diarrhoea; Discussion; Expression, regulation and the role of SLC26 C1/HCO exchangers in kidney and gastrointestinal tract; Discussion
Anion exchangers in flux: functional differences between human and mouse SLC26A6 polypeptidesDiscussion; Physiology of electrogenic SLC26 paralogues; Discussion; Role of SLC26-mediated C1/base exchange in proximal tubule NaCl transport; Discussion; SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion; Discussion; Regulatory interaction between CFTR and the SLC26 transporters; Discussion; Insights from a transgenic mouse model on the role of SLC26A2 in health and disease; Discussion New insights into the role of pendrin (SLC26A4) in inner ear fluid homeostasisDiscussion; The renal physiology of pendrin (SLC26A4) and its role in hypertension; Discussion; Interaction of prestin (SLC26A5) with monovalent intracellular anions; Discussion; Final discussion; Index of contributors; Subject index |
Record Nr. | UNINA-9910830298403321 |
Chichester, U.K., : John Wiley & Sons, 2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Epithelial anion transport in health and disease : the role of the SLC26 transporters family |
Pubbl/distr/stampa | Chichester, U.K., : John Wiley & Sons, 2006 |
Descrizione fisica | 1 online resource (285 p.) |
Disciplina | 572/.696 |
Collana | Novartis Foundation Symposium |
Soggetto topico |
Epithelial cells
Carrier proteins Ion channels |
ISBN |
1-280-51891-X
9786610518913 0-470-02957-9 0-470-02956-0 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Cover; Contents; Chair's introduction; Overview of the SLC26 family and associated diseases; Discussion; Individual characteristics of members of the SLC26 family in vertebrates and their homologues in insects; Discussion; Sulfate transport by SLC26 transporters; Discussion; Sugar transport by members of the SLC26 superfamily; Discussion; SLC26A3 and congenital chloride diarrhoea; Discussion; Expression, regulation and the role of SLC26 C1/HCO exchangers in kidney and gastrointestinal tract; Discussion
Anion exchangers in flux: functional differences between human and mouse SLC26A6 polypeptidesDiscussion; Physiology of electrogenic SLC26 paralogues; Discussion; Role of SLC26-mediated C1/base exchange in proximal tubule NaCl transport; Discussion; SLC26 transporters and the inhibitory control of pancreatic ductal bicarbonate secretion; Discussion; Regulatory interaction between CFTR and the SLC26 transporters; Discussion; Insights from a transgenic mouse model on the role of SLC26A2 in health and disease; Discussion New insights into the role of pendrin (SLC26A4) in inner ear fluid homeostasisDiscussion; The renal physiology of pendrin (SLC26A4) and its role in hypertension; Discussion; Interaction of prestin (SLC26A5) with monovalent intracellular anions; Discussion; Final discussion; Index of contributors; Subject index |
Record Nr. | UNINA-9910876871303321 |
Chichester, U.K., : John Wiley & Sons, 2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Expression and analysis of recombinant ion channels [[electronic resource] ] : from structural studies to pharmacological screening / / edited by Jeffrey J. Clare, Derek J. Trezise |
Pubbl/distr/stampa | Weinheim ; ; [Chichester], : Wiley-VCH, c2006 |
Descrizione fisica | 1 online resource (305 p.) |
Disciplina | 572.3 |
Altri autori (Persone) |
ClareJeffrey J
TreziseDerek J |
Soggetto topico |
Ion channels
Biological transport, Active |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-72342-4
9786610723423 3-527-60809-5 3-527-60793-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Expression and Analysis of Recombinant Ion Channels; Contents; Preface; List of Contributors; Color Plates; 1 Expression of Ion Channels in Xenopus Oocytes; 1.1 Introduction; 1.2 Advantages and Disadvantages of Xenopus Oocytes; 1.3 Procedures for Using Oocytes; 1.4 Types of Analyses; 1.4.1 Electrophysiological Analysis; 1.4.1.1 Two-electrode Whole Cell Voltage-clamp; 1.4.1.2 Cut-open Oocyte Voltage-clamp; 1.4.1.3 Macropatch Clamp; 1.4.1.4 Single Channel Analysis; 1.4.2 Biochemical Analysis; 1.4.3 Compound Screening; 1.4.3.1 Serial Recording Using the Roboocyte
1.4.3.2 Parallel Recording Using the OpusXpress1.5 Examples of Use; 1.5.1 Characterization of cDNA Clones for a Channel; 1.5.2 Structure-Function Correlations; 1.5.3 Studies of Human Disease Mutations; 1.6 Conclusions; Acknowledgments; References; 2 Molecular Biology Techniques for Structure - Function Studies of Ion Channels; 2.1 Introduction; 2.2 Methods for cDNA Subcloning; 2.2.1 Conventional Sub-cloning Using Restriction Enzymes and DNA Ligase; 2.2.2 PCR-based cDNA Sub-cloning; 2.2.3 Sub-cloning cDNA through Site-specific Recombination; 2.3 Generation of Chimeric Channel cDNAs 2.3.1 Use of Restriction Enzymes to Generate Chimeric Channel cDNAs2.3.2 PCR-mediated Overlap Extension for Chimera Generation; 2.3.3 PCR-mediated Integration or Replacement of cDNA Fragments; 2.4 Site-directed Mutagenesis; 2.4.1 Examples of the Use of Site-directed Mutagenesis; 2.4.2 Modification of the QuikChange Method for the Replacement of cDNA Fragments; 2.5 Epitope-tagged Channels and Fusion Partners; 2.6 Channel Subunit Concatamers; 2.7 Concluding Remarks; References; 3 Unnatural Amino Acids as Probes of Ion Channel Structure - Function and Pharmacology; 3.1 Introduction 3.2 Unnatural Amino Acid Mutagenesis Methodology3.3 Unnatural Amino Acid Mutagenesis for Ion Channel Studies; 3.4 Structure-Function Example Studies; 3.4.1 Nicotinic Acetylcholine Receptor; 3.4.2 Drug Interactions with the hERG Voltage-gated Potassium Ion Channel; 3.5 Other Uses of Unnatural Amino Acids as Probes of Protein Structure and Function; 3.6 Conclusions; Acknowledgements; References; 4 Functional Expression of Ion Channels in Mammalian Systems; 4.1 Introduction; 4.2 cDNA Cloning and Manipulation; 4.3 Choice of Host Cell Background 4.4 Post-translational Processing of Heterologous Expressed Ion Channels4.5 Cytotoxicity; 4.6 Transient Expression Systems; 4.6.1 "Standard" Transient Expression; 4.6.2 Viral Expression Systems; 4.7 Stable Expression of Ion Channels; 4.7.1 Bicistronic Expression Systems; 4.7.2 Stable Expression of Multiple Subunits; 4.7.3 Inducible Expression; 4.8 Summary; Acknowledgements; References; 5 Analysis of Electrophysiological Data; 5.1 Overview; 5.2 Introduction; 5.3 Expression Systems and Related Recording Techniques; 5.3.1 Expression in Xenopus Oocytes; 5.3.2 Expression in Mammalian Cells 5.3.3 Leak and Capacitance Subtraction |
Record Nr. | UNINA-9910143961803321 |
Weinheim ; ; [Chichester], : Wiley-VCH, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Expression and analysis of recombinant ion channels [[electronic resource] ] : from structural studies to pharmacological screening / / edited by Jeffrey J. Clare, Derek J. Trezise |
Pubbl/distr/stampa | Weinheim ; ; [Chichester], : Wiley-VCH, c2006 |
Descrizione fisica | 1 online resource (305 p.) |
Disciplina | 572.3 |
Altri autori (Persone) |
ClareJeffrey J
TreziseDerek J |
Soggetto topico |
Ion channels
Biological transport, Active |
ISBN |
1-280-72342-4
9786610723423 3-527-60809-5 3-527-60793-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Expression and Analysis of Recombinant Ion Channels; Contents; Preface; List of Contributors; Color Plates; 1 Expression of Ion Channels in Xenopus Oocytes; 1.1 Introduction; 1.2 Advantages and Disadvantages of Xenopus Oocytes; 1.3 Procedures for Using Oocytes; 1.4 Types of Analyses; 1.4.1 Electrophysiological Analysis; 1.4.1.1 Two-electrode Whole Cell Voltage-clamp; 1.4.1.2 Cut-open Oocyte Voltage-clamp; 1.4.1.3 Macropatch Clamp; 1.4.1.4 Single Channel Analysis; 1.4.2 Biochemical Analysis; 1.4.3 Compound Screening; 1.4.3.1 Serial Recording Using the Roboocyte
1.4.3.2 Parallel Recording Using the OpusXpress1.5 Examples of Use; 1.5.1 Characterization of cDNA Clones for a Channel; 1.5.2 Structure-Function Correlations; 1.5.3 Studies of Human Disease Mutations; 1.6 Conclusions; Acknowledgments; References; 2 Molecular Biology Techniques for Structure - Function Studies of Ion Channels; 2.1 Introduction; 2.2 Methods for cDNA Subcloning; 2.2.1 Conventional Sub-cloning Using Restriction Enzymes and DNA Ligase; 2.2.2 PCR-based cDNA Sub-cloning; 2.2.3 Sub-cloning cDNA through Site-specific Recombination; 2.3 Generation of Chimeric Channel cDNAs 2.3.1 Use of Restriction Enzymes to Generate Chimeric Channel cDNAs2.3.2 PCR-mediated Overlap Extension for Chimera Generation; 2.3.3 PCR-mediated Integration or Replacement of cDNA Fragments; 2.4 Site-directed Mutagenesis; 2.4.1 Examples of the Use of Site-directed Mutagenesis; 2.4.2 Modification of the QuikChange Method for the Replacement of cDNA Fragments; 2.5 Epitope-tagged Channels and Fusion Partners; 2.6 Channel Subunit Concatamers; 2.7 Concluding Remarks; References; 3 Unnatural Amino Acids as Probes of Ion Channel Structure - Function and Pharmacology; 3.1 Introduction 3.2 Unnatural Amino Acid Mutagenesis Methodology3.3 Unnatural Amino Acid Mutagenesis for Ion Channel Studies; 3.4 Structure-Function Example Studies; 3.4.1 Nicotinic Acetylcholine Receptor; 3.4.2 Drug Interactions with the hERG Voltage-gated Potassium Ion Channel; 3.5 Other Uses of Unnatural Amino Acids as Probes of Protein Structure and Function; 3.6 Conclusions; Acknowledgements; References; 4 Functional Expression of Ion Channels in Mammalian Systems; 4.1 Introduction; 4.2 cDNA Cloning and Manipulation; 4.3 Choice of Host Cell Background 4.4 Post-translational Processing of Heterologous Expressed Ion Channels4.5 Cytotoxicity; 4.6 Transient Expression Systems; 4.6.1 "Standard" Transient Expression; 4.6.2 Viral Expression Systems; 4.7 Stable Expression of Ion Channels; 4.7.1 Bicistronic Expression Systems; 4.7.2 Stable Expression of Multiple Subunits; 4.7.3 Inducible Expression; 4.8 Summary; Acknowledgements; References; 5 Analysis of Electrophysiological Data; 5.1 Overview; 5.2 Introduction; 5.3 Expression Systems and Related Recording Techniques; 5.3.1 Expression in Xenopus Oocytes; 5.3.2 Expression in Mammalian Cells 5.3.3 Leak and Capacitance Subtraction |
Record Nr. | UNINA-9910830623203321 |
Weinheim ; ; [Chichester], : Wiley-VCH, c2006 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|