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Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011
Descrizione fisica 1 online resource (219 p.)
Disciplina 611/.0187
Altri autori (Persone) SchulzMegan A
Collana Cell biology research progress
Soggetto topico Epithelial cells
Monomolecular films
Intestinal absorption
Soggetto genere / forma Electronic books.
ISBN 1-62081-613-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910465754103321
Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011
Descrizione fisica 1 online resource (219 p.)
Disciplina 611/.0187
Altri autori (Persone) SchulzMegan A
Collana Cell biology research progress
Soggetto topico Epithelial cells
Monomolecular films
Intestinal absorption
ISBN 1-62081-613-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910791742703321
Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Pubbl/distr/stampa Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Descrizione fisica 1 online resource (352 pages) : illustrations, charts
Disciplina 599/.01/32
Altri autori (Persone) ElliottKatherine May
WhelanJulie
Collana Ciba Foundation symposium (new series)
Soggetto topico Digestion
Intestinal absorption
Mammals - Physiology
ISBN 1-280-78388-5
9786613694270
0-470-72053-0
0-470-71821-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion
Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index
Record Nr. UNISA-996206965403316
Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Pubbl/distr/stampa Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Descrizione fisica 1 online resource (352 pages) : illustrations, charts
Disciplina 599/.01/32
Altri autori (Persone) ElliottKatherine May
WhelanJulie
Collana Ciba Foundation symposium (new series)
Soggetto topico Digestion
Intestinal absorption
Mammals - Physiology
ISBN 1-280-78388-5
9786613694270
0-470-72053-0
0-470-71821-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion
Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index
Record Nr. UNINA-9910144657603321
Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Descrizione fisica 1 online resource (352 pages) : illustrations, charts
Disciplina 599/.01/32
Altri autori (Persone) ElliottKatherine May
WhelanJulie
Collana Ciba Foundation symposium (new series)
Soggetto topico Digestion
Intestinal absorption
Mammals - Physiology
ISBN 9786613694270
9781280783883
1280783885
9780470720530
0470720530
9780470718216
0470718218
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion
Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index
Record Nr. UNINA-9910827880803321
Amsterdam ; ; New York : , : Excerpta Medica, , 1979
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Oral bioavailability [[electronic resource] ] : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
Oral bioavailability [[electronic resource] ] : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
Pubbl/distr/stampa Hoboken, NJ, : John Wiley & Sons, c2011
Descrizione fisica 1 online resource (570 p.)
Disciplina 615/.19
Altri autori (Persone) HuMing, Ph. D.
LiXiaoling <1957->
Collana Wiley series in drug discovery and development
Soggetto topico Drugs - Bioavailability
Drug development
Intestinal absorption
ISBN 1-283-25776-9
9786613257765
1-118-06758-4
1-118-06759-2
1-118-06752-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ORAL BIOAVAILABILITY; CONTENTS; Foreword; Preface; Contributors; 1 Barriers to Oral Bioavailability-An Overview; 2 Physicochemical Characterization of Pharmaceutical Solids; 3 Solubility of Pharmaceutical Solids; 4 In Vitro Dissolution of Pharmaceutical Solids; 5 Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption; 6 Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways; 7 In Vitro-In Vivo Correlations of Pharmaceutical Dosage Forms; 8 Drug Metabolism in Gastrointestinal Tract
9 Efflux of Drugs via Transporters-The Antiabsorption Pathway 10 Liver Drug Metabolism; 11 Protein Binding of Drugs; 12 Urinary Excretion of Drugs and Drug Reabsorption; 13 Pharmacokinetic Behaviors of Orally Administered Drugs; 14 Effects of Food on Drug Absorption; 15 Drug-Drug Interactions and Drug-Dietary Chemical Interactions; 16 Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans; 17 Amino Acid Drug Transporters; 18 Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals
19 Organic Anion and Cation Drug Transporters 20 Gastric Retentive Drug Delivery Systems; 21 Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems; 22 Prodrug Strategies to Enhance Oral Drug Absorption; 23 Oral Delivery of Protein/Peptide Therapeutics; 24 ABC Transporters in Intestinal and Liver Efflux; 25 Interplay Between Efflux Transporters and Metabolic Enzymes; 26 Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions; 27 Caco-2 Cell Culture Model for Oral Drug Absorption; 28 MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption
29 Intestinal Perfusion Methods for Oral Drug Absorptions 30 Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion; 31 In vivo Methods for Oral Bioavailability Studies; 32 Determination of Regulation of Drug-Metabolizing Enzymes and Transporters; 33 Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction; Index
Record Nr. UNINA-9910139611803321
Hoboken, NJ, : John Wiley & Sons, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Oral bioavailability : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
Oral bioavailability : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, NJ, : John Wiley & Sons, c2011
Descrizione fisica 1 online resource (570 p.)
Disciplina 615/.19
Altri autori (Persone) HuMing, Ph. D.
LiXiaoling <1957->
Collana Wiley series in drug discovery and development
Soggetto topico Drugs - Bioavailability
Drug development
Intestinal absorption
ISBN 9786613257765
9781283257763
1283257769
9781118067581
1118067584
9781118067598
1118067592
9781118067529
1118067525
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ORAL BIOAVAILABILITY; CONTENTS; Foreword; Preface; Contributors; 1 Barriers to Oral Bioavailability-An Overview; 2 Physicochemical Characterization of Pharmaceutical Solids; 3 Solubility of Pharmaceutical Solids; 4 In Vitro Dissolution of Pharmaceutical Solids; 5 Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption; 6 Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways; 7 In Vitro-In Vivo Correlations of Pharmaceutical Dosage Forms; 8 Drug Metabolism in Gastrointestinal Tract
9 Efflux of Drugs via Transporters-The Antiabsorption Pathway 10 Liver Drug Metabolism; 11 Protein Binding of Drugs; 12 Urinary Excretion of Drugs and Drug Reabsorption; 13 Pharmacokinetic Behaviors of Orally Administered Drugs; 14 Effects of Food on Drug Absorption; 15 Drug-Drug Interactions and Drug-Dietary Chemical Interactions; 16 Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans; 17 Amino Acid Drug Transporters; 18 Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals
19 Organic Anion and Cation Drug Transporters 20 Gastric Retentive Drug Delivery Systems; 21 Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems; 22 Prodrug Strategies to Enhance Oral Drug Absorption; 23 Oral Delivery of Protein/Peptide Therapeutics; 24 ABC Transporters in Intestinal and Liver Efflux; 25 Interplay Between Efflux Transporters and Metabolic Enzymes; 26 Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions; 27 Caco-2 Cell Culture Model for Oral Drug Absorption; 28 MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption
29 Intestinal Perfusion Methods for Oral Drug Absorptions 30 Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion; 31 In vivo Methods for Oral Bioavailability Studies; 32 Determination of Regulation of Drug-Metabolizing Enzymes and Transporters; 33 Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction; Index
Record Nr. UNINA-9910808327803321
Hoboken, NJ, : John Wiley & Sons, c2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Pubbl/distr/stampa Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Descrizione fisica 1 online resource (ix, 385 pages) : illustrations
Disciplina 574.1/9256
Collana Ciba Foundation symposium
Soggetto topico Peptides
Peptidase
Biological transport
Intestinal absorption
ISBN 0-444-15272-5
1-280-78366-4
0-470-71800-5
9786613694058
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion
Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index
Record Nr. UNINA-9910144659803321
Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Pubbl/distr/stampa Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Descrizione fisica 1 online resource (ix, 385 pages) : illustrations
Disciplina 574.1/9256
Collana Ciba Foundation symposium
Soggetto topico Peptides
Peptidase
Biological transport
Intestinal absorption
ISBN 0-444-15272-5
1-280-78366-4
0-470-71800-5
9786613694058
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion
Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index
Record Nr. UNISA-996202076403316
Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
Edizione [1st ed.]
Pubbl/distr/stampa Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Descrizione fisica 1 online resource (ix, 385 pages) : illustrations
Disciplina 574.1/9256
Collana Ciba Foundation symposium
Soggetto topico Peptides
Peptidase
Biological transport
Intestinal absorption
ISBN 9786613694058
9780444152725
0444152725
9781280783661
1280783664
9780470718001
0470718005
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion
Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index
Record Nr. UNINA-9910818861603321
Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui