Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
| Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011 |
| Descrizione fisica | 1 online resource (219 p.) |
| Disciplina | 611/.0187 |
| Altri autori (Persone) | SchulzMegan A |
| Collana | Cell biology research progress |
| Soggetto topico |
Epithelial cells
Monomolecular films Intestinal absorption |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-62081-613-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910465754103321 |
| Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor
| Caco-2 cells and their uses [[electronic resource] /] / Megan A. Schulz, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011 |
| Descrizione fisica | 1 online resource (219 p.) |
| Disciplina | 611/.0187 |
| Altri autori (Persone) | SchulzMegan A |
| Collana | Cell biology research progress |
| Soggetto topico |
Epithelial cells
Monomolecular films Intestinal absorption |
| ISBN | 1-62081-613-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910791742703321 |
| Hauppauge, N.Y., : Nova Science Publishers, Inc., c2011 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
| Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan] |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica, , 1979 |
| Descrizione fisica | 1 online resource (352 pages) : illustrations, charts |
| Disciplina | 599/.01/32 |
| Altri autori (Persone) |
ElliottKatherine May
WhelanJulie |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Digestion
Intestinal absorption Mammals - Physiology |
| ISBN |
1-280-78388-5
9786613694270 0-470-72053-0 0-470-71821-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index |
| Record Nr. | UNISA-996206965403316 |
| Amsterdam ; ; New York : , : Excerpta Medica, , 1979 | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
| Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan] |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica, , 1979 |
| Descrizione fisica | 1 online resource (352 pages) : illustrations, charts |
| Disciplina | 599/.01/32 |
| Altri autori (Persone) |
ElliottKatherine May
WhelanJulie |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Digestion
Intestinal absorption Mammals - Physiology |
| ISBN |
1-280-78388-5
9786613694270 0-470-72053-0 0-470-71821-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144657603321 |
| Amsterdam ; ; New York : , : Excerpta Medica, , 1979 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan]
| Development of mammalian absorptive processes / / [editors, Katherine Elliott (organizer), Julie Whelan] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica, , 1979 |
| Descrizione fisica | 1 online resource (352 pages) : illustrations, charts |
| Disciplina | 599/.01/32 |
| Altri autori (Persone) |
ElliottKatherine May
WhelanJulie |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Digestion
Intestinal absorption Mammals - Physiology |
| ISBN |
9786613694270
9781280783883 1280783885 9780470720530 0470720530 9780470718216 0470718218 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Development of Mammalian Absorptive Processes; Contents; Introduction; Morphogenesis of the small intestine during fetal development; Discussion; The differentiation and redifferentiation of the intestinal epithelium and its brush border membrane; Discussion; Cell surface components of intestinal epithelial cells and their relationship to cellular differentiation; Discussion; The role of lingual lipase in neonatal fat digestion; Discussion; Bile acid metabolism in the fetus and newborn; Discussion; Sucrase and cellular development; Discussion
Mode of insertion of the sucrase-isomaltase complex in the in testinal brush border membrane: implications for the biosynthe; Discussion; Development of sucrase activity: effect of maternal hormonal status and fetal programming of jejuno-ileal differences; Discussion; The role of enteropeptidase in the digestion of protein and its development in human fetal small intestine; Discussion; Absorption of di- and tripeptides by the intestine of the guinea-pig; Discussion; Gastrointestinal host defence: importance of gut closure in control of macromolecular transport; Discussion Membrane digestion and nutrient assimilation in early development; Discussion; Perinatal changes in the absorption of trace elements; Discussion; The influence of gestational age and size on the absorption of D-xylose and D-glucose from the small intestine of the human n; Discussion; Absorption of biological amines of bacterial origin in normal and sick infants; Discussion; The immature intestine: implications for nutrition of the neonate; Discussion; General Discussion; Future morphological studies; Hormonal mediation of gastrointestinal maturation; Sodium-dependent active transport; Nutritional needs of the premature infant; Lipid digestion in the newborn; Antigen uptake and immunity transfer; Index of contributors; Subject index |
| Record Nr. | UNINA-9910827880803321 |
| Amsterdam ; ; New York : , : Excerpta Medica, , 1979 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Oral bioavailability [[electronic resource] ] : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
| Oral bioavailability [[electronic resource] ] : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2011 |
| Descrizione fisica | 1 online resource (570 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
HuMing, Ph. D.
LiXiaoling <1957-> |
| Collana | Wiley series in drug discovery and development |
| Soggetto topico |
Drugs - Bioavailability
Drug development Intestinal absorption |
| ISBN |
1-283-25776-9
9786613257765 1-118-06758-4 1-118-06759-2 1-118-06752-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ORAL BIOAVAILABILITY; CONTENTS; Foreword; Preface; Contributors; 1 Barriers to Oral Bioavailability-An Overview; 2 Physicochemical Characterization of Pharmaceutical Solids; 3 Solubility of Pharmaceutical Solids; 4 In Vitro Dissolution of Pharmaceutical Solids; 5 Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption; 6 Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways; 7 In Vitro-In Vivo Correlations of Pharmaceutical Dosage Forms; 8 Drug Metabolism in Gastrointestinal Tract
9 Efflux of Drugs via Transporters-The Antiabsorption Pathway 10 Liver Drug Metabolism; 11 Protein Binding of Drugs; 12 Urinary Excretion of Drugs and Drug Reabsorption; 13 Pharmacokinetic Behaviors of Orally Administered Drugs; 14 Effects of Food on Drug Absorption; 15 Drug-Drug Interactions and Drug-Dietary Chemical Interactions; 16 Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans; 17 Amino Acid Drug Transporters; 18 Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals 19 Organic Anion and Cation Drug Transporters 20 Gastric Retentive Drug Delivery Systems; 21 Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems; 22 Prodrug Strategies to Enhance Oral Drug Absorption; 23 Oral Delivery of Protein/Peptide Therapeutics; 24 ABC Transporters in Intestinal and Liver Efflux; 25 Interplay Between Efflux Transporters and Metabolic Enzymes; 26 Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions; 27 Caco-2 Cell Culture Model for Oral Drug Absorption; 28 MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption 29 Intestinal Perfusion Methods for Oral Drug Absorptions 30 Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion; 31 In vivo Methods for Oral Bioavailability Studies; 32 Determination of Regulation of Drug-Metabolizing Enzymes and Transporters; 33 Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction; Index |
| Record Nr. | UNINA-9910139611803321 |
| Hoboken, NJ, : John Wiley & Sons, c2011 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Oral bioavailability : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li
| Oral bioavailability : basic principles, advanced concepts, and applications / / edited by Ming Hu, Xiaoling Li |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, NJ, : John Wiley & Sons, c2011 |
| Descrizione fisica | 1 online resource (570 p.) |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
HuMing, Ph. D.
LiXiaoling <1957-> |
| Collana | Wiley series in drug discovery and development |
| Soggetto topico |
Drugs - Bioavailability
Drug development Intestinal absorption |
| ISBN |
9786613257765
9781283257763 1283257769 9781118067581 1118067584 9781118067598 1118067592 9781118067529 1118067525 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
ORAL BIOAVAILABILITY; CONTENTS; Foreword; Preface; Contributors; 1 Barriers to Oral Bioavailability-An Overview; 2 Physicochemical Characterization of Pharmaceutical Solids; 3 Solubility of Pharmaceutical Solids; 4 In Vitro Dissolution of Pharmaceutical Solids; 5 Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption; 6 Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways; 7 In Vitro-In Vivo Correlations of Pharmaceutical Dosage Forms; 8 Drug Metabolism in Gastrointestinal Tract
9 Efflux of Drugs via Transporters-The Antiabsorption Pathway 10 Liver Drug Metabolism; 11 Protein Binding of Drugs; 12 Urinary Excretion of Drugs and Drug Reabsorption; 13 Pharmacokinetic Behaviors of Orally Administered Drugs; 14 Effects of Food on Drug Absorption; 15 Drug-Drug Interactions and Drug-Dietary Chemical Interactions; 16 Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans; 17 Amino Acid Drug Transporters; 18 Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals 19 Organic Anion and Cation Drug Transporters 20 Gastric Retentive Drug Delivery Systems; 21 Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems; 22 Prodrug Strategies to Enhance Oral Drug Absorption; 23 Oral Delivery of Protein/Peptide Therapeutics; 24 ABC Transporters in Intestinal and Liver Efflux; 25 Interplay Between Efflux Transporters and Metabolic Enzymes; 26 Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions; 27 Caco-2 Cell Culture Model for Oral Drug Absorption; 28 MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption 29 Intestinal Perfusion Methods for Oral Drug Absorptions 30 Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion; 31 In vivo Methods for Oral Bioavailability Studies; 32 Determination of Regulation of Drug-Metabolizing Enzymes and Transporters; 33 Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction; Index |
| Record Nr. | UNINA-9910808327803321 |
| Hoboken, NJ, : John Wiley & Sons, c2011 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
| Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 |
| Descrizione fisica | 1 online resource (ix, 385 pages) : illustrations |
| Disciplina | 574.1/9256 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Peptides
Peptidase Biological transport Intestinal absorption |
| ISBN |
0-444-15272-5
1-280-78366-4 0-470-71800-5 9786613694058 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910144659803321 |
| Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
| Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 |
| Descrizione fisica | 1 online resource (ix, 385 pages) : illustrations |
| Disciplina | 574.1/9256 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Peptides
Peptidase Biological transport Intestinal absorption |
| ISBN |
0-444-15272-5
1-280-78366-4 0-470-71800-5 9786613694058 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNISA-996202076403316 |
| Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor
| Peptide transport and hydrolysis / / editors, Katherine Elliott, Maeve O'Connor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 |
| Descrizione fisica | 1 online resource (ix, 385 pages) : illustrations |
| Disciplina | 574.1/9256 |
| Collana | Ciba Foundation symposium |
| Soggetto topico |
Peptides
Peptidase Biological transport Intestinal absorption |
| ISBN |
9786613694058
9780444152725 0444152725 9781280783661 1280783664 9780470718001 0470718005 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Peptide Transport and Hydrolysis; Contents; Chairman's opening remarks; Introduction; Amino acid and peptide absorption in man; Discussion of the two preceding papers; Intestinal dipeptidases and dipeptide transport in the monkey and in man; Discussion; Dipeptide transport in the intestinal mucosa of developing rabbits; Discussion; Mechanisms of peptide transport; Discussion; A brush-border-bound peptidase and amino acid transport; Discussion; The function of the γ-glutamyl cycle in the transport of amino acids and peptides; Discussion; General Discussion I
Intestinal mucosal hydrolysis of proteins and peptides; Discussion; Intestinal brush border peptidases; Discussion; Intracellular hydrolysis of peptides; Endopeptidases in the brush border of the kidney proximal tubule; Discussion of the two preceding papers; Membrane and intracellular hydrolysis of peptides : differentiation, role and interrelations with transport; Discussion; Intestinal hydrolysis of disaccharides and peptides : comparison of hydrolases and perfusion studies; Discussion; Clearance of dipeptides from plasma: role of kidney and intestine; Discussion Peptiduria in the Fanconi syndrome; Discussion; General Discussion II; Coeliac disease; Transport and hydrolysis of peptides by microorganisms; Discussion; Peptidases in germinating barley grain: properties, localization and possible functions; Discussion; Final Discussion; Site of peptide hydrolysis; Peptide transport through membranes; Membrane digestion of peptides; Epithelial transport of peptides; Rate-limiting steps : hydrolysis or transport?; Closing remarks; Index of contributors; Subject index |
| Record Nr. | UNINA-9910818861603321 |
| Amsterdam ; ; New York : , : Elsevier/Excerpta Medica/North Holland, , 1977 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||