Enterobacter sakazakii / / Jeffrey M. Farber, Stephen J. Forsythe, Michael P. Doyle, editors
| Enterobacter sakazakii / / Jeffrey M. Farber, Stephen J. Forsythe, Michael P. Doyle, editors |
| Pubbl/distr/stampa | Washington, D.C. : , : ASM Press, , 2008 |
| Descrizione fisica | 1 online resource (xii, 271 pages) : illustrations |
| Disciplina | 612.33 |
| Collana | Emerging issues in food safety |
| Soggetto topico |
Intestines - Microbiology
Enterobacter sakazakii Infant formulas - Contamination |
| ISBN | 1-68367-154-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Taxonomy and physiology of Enterobacter sakazakii / Catherine Dauga and Pieter Breeuwer -- Isolation and identification of Enterobacter sakazakii / Séamus Fanning and Stephen J. Forsythe -- The neonatal intestinal microbial flora, immunity, and infections / Stacy Townsend and Stephen J. Forsythe -- Enterobacter sakazakii disease and epidemiology / Anna B. Bowen and Christopher R. Braden -- Pathogenicity of Enterobacter sakazakii / Franco Pagotto, Jeffrey M. Farber, and Raquel Lenati -- Production of powdered infant formulae and microbiological control measures / Jean-Louis Cordier -- Use of nonsterile nutritionals for neonates in the hospital and after hospital discharge: control measures currently instituted at one tertiary care institution / Deborah L. O'Connor [and others] -- Powdered infant formula in developing and other countries: issues and prospects / S. Estuningsih and N. Abdullah Sani -- Regulatory aspects / Jeffrey M. Farber, Franco Pagotto, and Jean-Louis Cordier -- Enterobacter sakazakii: personal perspectives and reminiscences from a 32-year history / J.J. Farmer, III. |
| Record Nr. | UNINA-9910830125903321 |
| Washington, D.C. : , : ASM Press, , 2008 | ||
| Lo trovi qui: Univ. Federico II | ||
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Pesticides in the diets of infants and children [[electronic resource] /] / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council
| Pesticides in the diets of infants and children [[electronic resource] /] / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (401 p.) |
| Disciplina | 615.9/54 |
| Soggetto topico |
Pediatric toxicology
Pesticide residues in food - United States Pesticides - Toxicology Infant formulas - Contamination Food contamination |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-19660-2
9786610196609 0-309-58535-X 0-585-03066-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910455875303321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticides in the diets of infants and children [[electronic resource] /] / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council
| Pesticides in the diets of infants and children [[electronic resource] /] / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (401 p.) |
| Disciplina | 615.9/54 |
| Soggetto topico |
Pediatric toxicology
Pesticide residues in food - United States Pesticides - Toxicology Infant formulas - Contamination Food contamination |
| ISBN |
1-280-19660-2
9786610196609 0-309-58535-X 0-585-03066-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778796303321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Pesticides in the diets of infants and children / / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council
| Pesticides in the diets of infants and children / / Committee on Pesticides in the Diets of Infants and Children, Board on Agriculture and Board on Environmental Studies and Toxicology, Commission on Life Science, National Research Council |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1993 |
| Descrizione fisica | 1 online resource (401 p.) |
| Disciplina | 615.9/54 |
| Soggetto topico |
Pediatric toxicology
Pesticide residues in food - United States Pesticides - Toxicology Infant formulas - Contamination Food contamination |
| ISBN |
9786610196609
9781280196607 1280196602 9780309585354 030958535X 9780585030661 0585030669 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
PESTICIDES in the DIETS OF INFANTS AND CHILDREN -- Copyright -- Preface -- Contents -- Executive Summary -- CONCLUSIONS -- Age-Related Variation in Susceptibility and Toxicity -- Age-Related Differences in Exposure -- A New Approach to Risk Assessment for Infants and Children -- RECOMMENDATIONS -- 1 Background and Approach to the Study -- PESTICIDE USE -- PESTICIDE CONTROL LEGISLATION -- APPROACH TO THE STUDY -- REFERENCES -- 2 Special Characteristics of Children -- GROWTH -- Normal Human Growth -- Human Compared to Animal Infants -- Toxicologic Implications of Growth in Cell Numbers and Size -- Toxicologic Implications of the Growth and Development of Organs -- Toxicologic Implications of Changes in Body Composition -- DEVELOPMENT -- Genetics, Development, and the Environment -- Metabolism -- Developmental Toxicity Studies -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 3 Perinatal and Pediatric Toxicity -- ACUTE TOXICITY -- NEUROTOXICITY -- Postnatal Effects of Neurotoxicants -- Measuring Neurotoxic Effects in Humans -- The Lead Model -- Pesticides as Neurotoxicants -- Effects of Pesticides in Children -- Levels of Pesticides Affecting Children -- Comparability of Neurotoxicity Effects in Laboratory Animals -- IMMUNOTOXICITY -- Effects of Environmental Agents on the Immune System -- Animal Studies -- Studies in Humans -- CARCINOGENESIS AND MUTAGENESIS -- Carcinogenesis in the Developing Organism -- Animal Studies -- Human Studies -- METABOLISM AND PHARMACOKINETICS -- Dermal and Pulmonary Exposure -- Oral Exposure -- Absorption -- Other Factors Affecting Oral Absorption -- Distribution and Uptake of Chemicals -- Retention -- Metabolism of Xenobiotic Compounds -- Excretion -- SCALING AND REGRESSION ANALYSIS -- Body Weight -- Other Effects of Body Size -- Surface Area -- Metabolic Rate -- Regression Analysis.
CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 4 Methods for Toxicity Testing -- CURRENT METHODS: GENERAL CONSIDERATIONS -- ACUTE TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- SUBCHRONIC TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- CHRONIC TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- DEVELOPMENTAL TOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- REPRODUCTION STUDIES -- General Description -- EPA's Proposed Changes -- MUTAGENICITY STUDIES -- General Description -- EPA's Proposed Changes -- GENERAL METABOLISM STUDIES -- General Description -- EPA's Proposed Changes -- NEUROTOXICITY STUDIES -- General Description -- EPA's Proposed Changes -- SPECIAL TESTING -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 5 Food and Water Consumption -- FOOD CONSUMPTION SURVEYS -- SURVEY METHODOLOGY -- Retrospective Methods -- The 24-Hour (or 1-Day) Recall Method -- Food Frequency Questionnaires -- Prospective Methods -- Food Records or Diaries -- Combined Retrospective and Prospective Methods -- Methods Used in USDA Surveys -- SURVEY DESIGN -- SAMPLE WEIGHTS -- SAMPLE SIZE -- COMPARISONS OF INTAKE DATA WITH STANDARDS -- VALIDATION OF FOOD CONSUMPTION DATA -- THE STRENGTHS AND WEAKNESSES OF THE FOOD CONSUMPTION DATA BASES IN ESTIMATING PESTICIDE EXPOSURE OF CHILDREN -- WATER INTAKE -- Dietary Sources of Water -- Water Intake Estimates -- QUANTIFICATION OF CONSUMPTION DATA -- AGE-RELATED DIFFERENCES IN DIETARY PATTERNS -- ISSUES RELATED TO THE EVALUATION OF FOOD MONITORING DATA -- Differences in Consumption Among Age Groups -- Differences in Consumption within Age Groups -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 6 Pesticide Residues -- SOURCES OF DATA ON USAGE. THE OCCURRENCE AND FATE OF PESTICIDE RESIDUES -- PESTICIDE REGISTRATION AND THE DEVELOPMENT OF ANALYTICAL METHODS -- Interregional Project Number 4 -- Universities and the ARS -- METHODS FOR SAMPLING AND ANALYSIS -- Sampling -- Analysis -- Single Residue Methods -- Multiresidue Methods -- Criteria for Selecting a Method -- Single Residue Methods or Multiresidue Methods? -- Breadth of Applicability -- Detection Limits -- Accuracy and Precision -- Speed and Cost -- Instrumentation -- Validation -- MONITORING -- Federal Activities -- State Activities -- Food Processing Industry Activities -- Private Laboratories -- QUALITY CONTROLS -- LIMITATIONS OF THE DATA -- Sources of Error -- Other Limitations -- PESTICIDES IN WATER -- Groundwater -- Surface Water -- The Importance of Water Data to Infants and Children -- PESTICIDES IN INFANT FORMULA -- Infant Formula Based on Cow's Milk -- Soy-Based Infant Formula -- Theoretical Maximum Residue Contributions -- PESTICIDES IN HUMAN MILK -- DDT and Metabolites -- Dieldrin -- Lindane -- Hexachlorobenzene -- Other Cyclodiene Pesticides -- Risks to Infants from Pesticides in Human Milk -- PESTICIDES IN FOODS -- The FDA Surveillance Data -- Number of FDA Samples -- Positive Detections -- Residue Levels -- Residue Distribution -- Effects of Processing -- Apple-Based Foods -- Infant Cereal -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 7 Estimating Exposures -- THE USED OF FOOD CONSUMPTION AND RESIDUE DATA FOR EXPOSURE ASSESSMENT -- Food Consumption Data -- Average Levels of Consumption -- Peak Levels of Consumption -- Residue Monitoring -- Combining Residue and Exposure Data -- LONG-TERM EXPOSURE TO BENOMYL -- The Compound -- The Consumption Data -- The Residue Data -- Estimation of Exposure -- The Manufacturer's Field Trials -- The Manufacturer's Market Basket Survey. FDA Surveillance Data -- The Food Industry -- A Certification Business -- Summary -- SHORT-TERM EXPOSURE TO ALDICARB -- The Compound -- Acute Effects of Dietary Aldicarb Exposure -- The Consumption Data -- The Residue Data -- Effects of Assumptions Regarding Residues Below the LOQ -- Estimating Dietary Exposure -- Summary -- MULTIPLE EXPOSURE ASSESSMENT: ORGANOPHOSPHATE INSECTICIDES -- Cholinesterase Inhibition -- Relative Potency of Organophosphates -- Food Consumption Data -- Residue Data -- Exposure Analysis -- Summary -- NONDIETARY EXPOSURE TO PESTICIDES -- Exposure via Parents -- Exposure Through Air -- Outdoor Air -- Indoor Air -- Exposure via Contaminated Surfaces -- Home-Use Products -- Pet Products -- Playground Equipment -- Exposure via Medications and Personal Products -- N,N-Diethyl-m-toluamide -- Lindane and Malathion -- Lanolin -- Occupational Exposures -- Exposure via Accidental Ingestion -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- 8 Estimating the Risks -- GENERAL PRINCIPLES OF RISK ASSESSMENT -- Toxicological Risk Assessment -- Cancer Risk Estimation -- Additivity to Background and Low-Dose Linearity -- Nonlinearity at High Doses -- Molecular Dosimetry -- Mathematical Modeling of Cancer Risk -- Species Conversion -- Benchmark Dose -- RISK ASSESSMENT FOR INFANTS AND CHILDREN -- Pharmacokinetics -- Pregnancy, Lactation, and Nursing -- Neurotoxicity -- Multiple Exposures -- Inert Ingredients -- Considerations Specific to Children -- Exposure and Low Socioeconomic Status -- Age-Dependent Toxicity -- Genetic Susceptibility -- Polymorphism in Metabolism -- Chronic Medical Conditions -- Interactions with Medication -- Acetylcholinesterase Inhibitors -- Antiepileptic Pharmaceuticals -- Other Pharmaceuticals -- Carcinogenesis -- Factors That Might Increase Risk of Cancer Among Infants and Children. Effects of Age-Dependent Exposures -- Consumption and Exposure Data -- CONCLUSIONS AND RECOMMENDATIONS -- Conclusions -- Recommendations -- REFERENCES -- Index. |
| Record Nr. | UNINA-9910960214803321 |
| Washington, D.C., : National Academy Press, 1993 | ||
| Lo trovi qui: Univ. Federico II | ||
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