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Biologic markers in immunotoxicology [[electronic resource] /] / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.]
| Biologic markers in immunotoxicology [[electronic resource] /] / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 615.9/07 |
| Soggetto topico |
Immunotoxicology
Biochemical markers |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-21206-3
9786610212064 0-309-59504-5 0-585-02611-4 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910454883703321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biologic markers in immunotoxicology [[electronic resource] /] / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.]
| Biologic markers in immunotoxicology [[electronic resource] /] / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 615.9/07 |
| Soggetto topico |
Immunotoxicology
Biochemical markers |
| ISBN |
1-280-21206-3
9786610212064 0-309-59504-5 0-585-02611-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910778876703321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biologic markers in immunotoxicology / / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.]
| Biologic markers in immunotoxicology / / Subcommittee on Immunotoxicology, Committee on Biologic Markers ... [et al.] |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Washington, D.C., : National Academy Press, 1992 |
| Descrizione fisica | 1 online resource (224 p.) |
| Disciplina | 615.9/07 |
| Soggetto topico |
Immunotoxicology
Biochemical markers |
| ISBN |
1-280-21206-3
9786610212064 0-309-59504-5 0-585-02611-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Biologic Markers in Immunotoxicology -- Copyright -- Preface -- Contents -- List of Abbreviations -- Summary -- HYPERSENSITIVITY -- AUTOIMMUNITY -- IMMUNE SUPPRESSION -- BIOASSAYS OF IMMUNOTOXICITY -- CLINICAL APPLICATION OF EXISTING IMMUNOTOXICOLOGIC BIOLOGIC MARKERS -- ROLE OF BIOLOGIC MARKERS OF IMMUNOTOXICITY IN EPIDEMIOLOGY -- INDOOR AIR POLLUTION AND MULTIPLE CHEMICAL SENSITIVITY -- 1 Introduction -- BIOLOGIC MARKERS -- Markers of Exposure -- Markers of Effect -- Markers of Susceptibility -- VALIDITY OF BIOLOGIC MARKERS -- UNCERTAINTY AND RISK -- ETHICAL AND PRACTICAL ISSUES -- STRUCTURE OF THE REPORT -- 2 The Structure and Function Of the Immune System And Mechanisms of Immunotoxicity -- DEVELOPMENT AND FUNCTION OF THE IMMUNE SYSTEM -- MECHANISMS OF CHEMICALLY INDUCED IMMUNE DISEASE -- IgE-Mediated Hypersensitivity -- Complement-Mediated and Immune-Complex-Mediated Injury -- T-Cell Reactions -- EFFECTS OF XENOBIOTICS ON THE IMMUNE SYSTEM -- 3 Biologic Markers For Immune-Mediated Disease -- DEFINITION OF THE PROBLEM -- EXPOSURE THROUGH INHALATION (PULMONARY HYPERSENSITIVITY) -- Occupational Asthma and Rhinitis -- Hypersensitivity Pneumonitis -- EXPOSURE THROUGH INGESTION -- DERMAL EXPOSURE -- Contact Dermatitis -- Photocontact Dermatitis -- Contact Urticaria -- NONSPECIFIC IMMUNE ENHANCEMENT -- BIOLOGIC MARKERS OF HYPERSENSITIVITY -- History and Clinical Signs -- Skin Tests -- Serum IgE Concentration -- In Vitro Assays for Specific Antibody -- In Vitro Assays for Cellular Immunity -- Provocation Challenges -- Bronchoalveolar Lavage -- ANIMAL MODELS FOR DETECTING CHEMICALLY MEDIATED HYPERSENSITIVITY -- Techniques Used in Animal Studies to Determine the Potential of Chemicals to Cause Hypersensitivity -- IgE-and IgG-Mediated Immediate Reactions -- Cytotoxic Reactions -- Antigen-Antibody Complexes -- Contact Hypersensitivity -- SUMMARY.
RECOMMENDATIONS FOR FUTURE RESEARCH -- IgE Sensitivity -- Immunologically Mediated Adverse Reactions -- Local Versus Systemic Immunity -- Sensitizers -- Individual Differences in Sensitivity -- Development of Self-Antigens -- Effects of Exposure Conditions -- Epidemiology -- IGE AND CELLULAR IMMUNITY -- Cellular and Antibody Immunity -- Individual Variability -- Local Versus Systemic Immunity -- Organic Versus Chemical Hypersensitivity -- Effects of Exposure -- Particle Composition -- Chemical Haptens -- 4 Autoimmune Diseases -- DEFINITION OF THE PROBLEM -- INCIDENCE OF AUTOIMMUNE DISEASES -- SUSCEPTIBILITY VERSUS EXPOSURE -- XENOBIOTIC-INDUCED AUTOIMMUNITY -- MECHANISMS -- ANIMAL MODELS -- BIOLOGIC MARKERS -- MAJOR HISTOCOMPATIBILITY COMPLEX -- IMMUNOGLOBULIN ALLOTYPES -- OTHER GENETIC MARKERS -- RATE OF ACETYLATION -- Antinuclear Antibodies -- Specific Tissue Autoantibodies -- Histopathologic Examination -- Immune Complexes -- Complement -- SUMMARY AND RECOMMENDATIONS -- 5 The Capacity of Toxic Agents to Compromise the Immune System (Biologic Markers of Immunosuppression) -- CONSEQUENCES OF IMMUNOSUPPRESSION -- ENVIRONMENTAL CONTAMINANTS -- Human Studies -- Experimental Studies -- Aromatic Hydrocarbons -- Benzene -- Metals -- Complex Mixtures -- Miscellaneous -- INHALATION AND IMMUNOSUPPRESSION -- SKIN AND IMMUNOSUPPRESSION -- MYELOTOXICITY AND IMMUNOSUPPRESSION -- DIFFICULTIES IN ESTABLISHING HUMAN RISK -- FACTORS THAT AFFECT SUSCEPTIBILITY -- Age and External Factors -- Metabolic Differences -- Species Differences -- IMPORTANCE OF MECHANISTIC STUDIES -- SUMMARY -- RECOMMENDATIONS -- 6 Animal Models for Use in Detecting Immunotoxic Potential And Determining Mechanisms of Action -- ANIMAL IMMUNOTOXICITY BIOASSAYS -- Pathologic Evaluation -- Humoral Immunity -- Cellular Immunity -- Nonspecific Immunity -- Bone Marrow -- Host Resistance. Mechanistic Studies -- ASSAYS OF PULMONARY IMMUNOCOMPETENCE -- ASSAYS REQUIRING ADDITIONAL DEVELOPMENT -- USE OF IMMUNOTOXICITY BIOASSAYS -- Considerations in the Design of Immunotoxicity Testing -- Immunotoxicity as a Basis for Risk Assessment -- SUMMARY -- RECOMMENDATIONS -- 7 Human Immune-System Biologic Markers of Immunotoxicity -- TESTS FOR ASSESSING IMMUNITY -- TESTS OF THE HUMORAL IMMUNE SYSTEM -- Immunoglobulin Concentration -- Antibody Formation -- B Cells -- CELLULAR IMMUNE SYSTEM -- Skin Testing -- In Vitro Stimulation of Lymphocytes -- OTHER TESTS -- OPPORTUNITIES FOR DEVELOPMENT OF BIOLOGIC MARKERS THAT ASSESS THE EFFECT OF IMMUNOTOXICANTS -- Primary Humoral Immune Responses -- Activation Antigens on Lymphocyte Surfaces and in Serum -- Synthesis and Secretion of Lymphokines After Lymphocyte Activation -- Proliferative Responses to Super-Antigens -- Self-HLA-Restricted Cell-Mediated Cytotoxicity -- PROPOSED TESTING REGIMEN -- SUMMARY -- RECOMMENDATIONS -- 8 Application of Biologic Markers Of Immunotoxicity in Epidemiology -- EPIDEMIOLOGY -- CONTRIBUTION OF BIOLOGIC MARKERS TO EPIDEMIOLOGY -- VARIABILITY IN REFERENCE POPULATIONS -- SENSITIVITY, SPECIFICITY, AND PREDICTIVE VALUE -- AUTHENTICATION OF THE EVENT STATUS -- STUDY DESIGN -- REFERENCE POPULATIONS -- CASE STUDIES -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- Background -- Study Design -- Results -- Strengths -- Limitations -- RECOMMENDATIONS -- 9 Use of Biologic Markers In Controversial Areas Of Environmental Health -- EVIDENCE OF EXPOSURE TO ORGANIC CHEMICALS -- HEALTH EFFECTS OF INDOOR AIR CONTAMINANTS -- CASE DEFINITIONS OF MULTIPLE-CHEMICAL-SENSITIVITY SYNDROME -- IMMUNE-SYSTEM DYSFUNCTION IN MCS PATIENTS. BIOLOGIC MARKERS OF SENSITIVITY TO CHEMICALS -- Provocative Challenge -- Skin Tests -- ANTIBODIES TO FORMALDEHYDE-HUMAN SERUM ALBUMIN ADDUCTS -- Avoidance Regimens -- T-cell Helper-to-Suppressor Ratios -- CONCLUSIONS -- RECOMMENDATIONS -- 10 Summary and Recommendations -- CHEMICAL-INDUCED IMMUNOSUPPRESSION IN HUMANS -- Conclusions -- Recommendations -- ROLE OF ENVIRONMENTAL CHEMICAL EXPOSURE IN HYPERSENSITIVITY AND AUTOIMMUNE DISEASES -- Conclusions -- Recommendations -- ANIMAL AND IN VITRO MODELS -- Conclusions -- Recommendations -- MARKERS OF SKIN AND MUCOSAL RESPONSES -- Conclusions -- Recommendations -- EDUCATION AND TRAINING -- Conclusions -- Recommendations -- ENVIRONMENTAL EXPOSURES AND SENSITIVITY SYNDROMES -- Conclusions -- Recommendations -- REFERENCES -- Glossary -- BIOGRAPHIES -- INDEX. |
| Record Nr. | UNINA-9910817058503321 |
| Washington, D.C., : National Academy Press, 1992 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Guidance for industry [[electronic resource] ] : S8 immunotoxicity studies for human pharmaceuticals
| Guidance for industry [[electronic resource] ] : S8 immunotoxicity studies for human pharmaceuticals |
| Pubbl/distr/stampa | Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research : , : Center for Biologics Evaluation and Research, , [2006] |
| Descrizione fisica | 13 pages : digital, PDF file |
| Soggetto topico |
Immunotoxicology
Drugs - Testing |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Guidance for industry |
| Record Nr. | UNINA-9910698979003321 |
| Rockville, MD : , : U.S. Dept. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research : , : Center for Biologics Evaluation and Research, , [2006] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunology . Volume 1 Immunotoxicology, immunopathology, and immunotherapy / / edited by M.A. Hayat, Distinguished Professor, Kean University, Union, NJ, United States
| Immunology . Volume 1 Immunotoxicology, immunopathology, and immunotherapy / / edited by M.A. Hayat, Distinguished Professor, Kean University, Union, NJ, United States |
| Pubbl/distr/stampa | London : , : Academic Press, an imprint of Elsevier, , [2018] |
| Descrizione fisica | 1 online resource (xxix, 255 pages) : illustrations (some color) |
| Disciplina | 616.97 |
| Collana | Immunology |
| Soggetto topico |
Immunology
Immunotoxicology Immunopathology Immunotherapy |
| ISBN | 0-12-809897-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Molecular mechanisms -- 2. Role in disease and treatment. |
| Record Nr. | UNINA-9910583497903321 |
| London : , : Academic Press, an imprint of Elsevier, , [2018] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunopharmacology and immunotoxicology
| Immunopharmacology and immunotoxicology |
| Pubbl/distr/stampa | [New York, NY], : Marcel Dekker, : 1987- |
| Disciplina | 616.079 |
| Soggetto topico |
Immunopharmacology
Immunotoxicology Immunotoxins Allergy and Immunology Pharmacology Communicable Diseases Immunology Toxicology |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1532-2513 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910154517503321 |
| [New York, NY], : Marcel Dekker, : 1987- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunotoxicology of environmental and occupational metals / / edited by Judith Zelikoff and Peter T. Thomas
| Immunotoxicology of environmental and occupational metals / / edited by Judith Zelikoff and Peter T. Thomas |
| Pubbl/distr/stampa | London ; ; Bristol, Penn. : , : Taylor & Francis, , 1998 |
| Descrizione fisica | 1 online resource (385 p.) |
| Disciplina | 615.902 |
| Altri autori (Persone) |
ZelikoffJudith T
ThomasPeter T |
| Soggetto topico |
Heavy metals - Toxicology
Immunotoxicology |
| ISBN |
1-135-74502-1
0-429-21796-X 1-135-74503-X 1-280-40256-3 0-203-29052-6 9786610402564 0-203-21187-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Book Cover; Title; Contents; Preface; Acknowledgment; List of contributors; Arsenic; Beryllium; Cadmium; Chromium; Indium; Lead; Mercury; Nickel; Platinum; Vanadium; Iron, Zinc, and Copper; Immunotoxicology Summary Tables; Index |
| Record Nr. | UNINA-9910279587503321 |
| London ; ; Bristol, Penn. : , : Taylor & Francis, , 1998 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunotoxicology strategies for pharmaceutical safety assessment [[electronic resource] /] / edited by Danuta J. Herzyk and Jeanine L. Bussiere
| Immunotoxicology strategies for pharmaceutical safety assessment [[electronic resource] /] / edited by Danuta J. Herzyk and Jeanine L. Bussiere |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2008 |
| Descrizione fisica | 1 online resource (432 p.) |
| Disciplina |
615.19
616.97/071 |
| Altri autori (Persone) |
HerzykDanuta J
BussiereJeanine L |
| Soggetto topico |
Immunotoxicology
Immune system - Effect of drugs on Toxicity testing Drugs - Toxicology |
| ISBN |
1-281-78802-3
9786611788025 0-470-38638-X 0-470-38637-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings -- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans -- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley --
Need for specialized immunotoxicity tests / Kazuichi Nakamura -- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj -- T cell-dependent antibody response tests / Joseph R. Piccotti -- Natural killer cell assay and other innate immunity tests / Lisa Plitnick -- Cellular immune response in delayed-type hypersensitivity test / Karen Price -- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek -- Functional cellular responses and cytokine profiles / Elizabeth R. Gore -- Application of flow cytometry in drug development / Padma Narayanan ... [et al.] -- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson -- Approaches to evaluation of autoimmunity / Danuta J. Herzyk -- Differentiating between desired immunomodulation and potential immunotoxicity / Jeanine L. Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House -- Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.] -- Systemic hypersensitivity / Raymond Pieters -- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier -- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas -- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse -- Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski -- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda -- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer -- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes. |
| Record Nr. | UNINA-9910143986903321 |
| Hoboken, N.J., : Wiley, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunotoxicology strategies for pharmaceutical safety assessment [[electronic resource] /] / edited by Danuta J. Herzyk and Jeanine L. Bussiere
| Immunotoxicology strategies for pharmaceutical safety assessment [[electronic resource] /] / edited by Danuta J. Herzyk and Jeanine L. Bussiere |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2008 |
| Descrizione fisica | 1 online resource (432 p.) |
| Disciplina |
615.19
616.97/071 |
| Altri autori (Persone) |
HerzykDanuta J
BussiereJeanine L |
| Soggetto topico |
Immunotoxicology
Immune system - Effect of drugs on Toxicity testing Drugs - Toxicology |
| ISBN |
1-281-78802-3
9786611788025 0-470-38638-X 0-470-38637-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings -- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans -- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley --
Need for specialized immunotoxicity tests / Kazuichi Nakamura -- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj -- T cell-dependent antibody response tests / Joseph R. Piccotti -- Natural killer cell assay and other innate immunity tests / Lisa Plitnick -- Cellular immune response in delayed-type hypersensitivity test / Karen Price -- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek -- Functional cellular responses and cytokine profiles / Elizabeth R. Gore -- Application of flow cytometry in drug development / Padma Narayanan ... [et al.] -- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson -- Approaches to evaluation of autoimmunity / Danuta J. Herzyk -- Differentiating between desired immunomodulation and potential immunotoxicity / Jeanine L. Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House -- Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.] -- Systemic hypersensitivity / Raymond Pieters -- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier -- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas -- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse -- Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski -- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda -- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer -- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes. |
| Record Nr. | UNINA-9910830841703321 |
| Hoboken, N.J., : Wiley, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Immunotoxicology strategies for pharmaceutical safety assessment / / edited by Danuta J. Herzyk and Jeanine L. Bussiere
| Immunotoxicology strategies for pharmaceutical safety assessment / / edited by Danuta J. Herzyk and Jeanine L. Bussiere |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley, c2008 |
| Descrizione fisica | 1 online resource (432 p.) |
| Disciplina | 616.97/071 |
| Altri autori (Persone) |
HerzykDanuta J
BussiereJeanine L |
| Soggetto topico |
Immunotoxicology
Immune system - Effect of drugs on Toxicity testing Drugs - Toxicology |
| ISBN |
1-281-78802-3
9786611788025 0-470-38638-X 0-470-38637-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Current regulatory expectations for immunotoxicologyy evaluation of pharmaceuticals / Kenneth L. Hastings -- Clinical pathology as crucial insight into immunotoxicity testing / Ellen Evans -- Histomorphology of the immune system : a basic step in assessing immunotoxicity / Patrick Haley --
Need for specialized immunotoxicity tests / Kazuichi Nakamura -- Specific drug-induced immunotoxicity : immune-mediated hemolytic anemia / Raj Krishnaraj -- T cell-dependent antibody response tests / Joseph R. Piccotti -- Natural killer cell assay and other innate immunity tests / Lisa Plitnick -- Cellular immune response in delayed-type hypersensitivity test / Karen Price -- Evaluation of drug effects on immune cell phenotypes / Laurie Iciek -- Functional cellular responses and cytokine profiles / Elizabeth R. Gore -- Application of flow cytometry in drug development / Padma Narayanan ... [et al.] -- Animal models of host resistance / Gary R. Burleson and Florence G. Burleson -- Approaches to evaluation of autoimmunity / Danuta J. Herzyk -- Differentiating between desired immunomodulation and potential immunotoxicity / Jeanine L. Bussiere and Barbara Mounho -- Relevant immune tests across different species and surrogate models / Jeanine L. Bussiere -- Antidrug antibody responses in nonclinical studies and their implications / Barbara Mounho -- Pharmacological immunogenicity and adverse responses to vaccines / Mary Kate Hart, Mark Bolanowski, and Robert V. House -- Immunotoxicological concerns for vaccines and adjuvants / Catherine Kaplanski ... [et al.] -- Systemic hypersensitivity / Raymond Pieters -- Nonclinical models to assess respiratory hypersensitivity potential / Curtis C. Maier -- Developmental immunotoxicity in rodents / Rodney R. Dietert and Leigh Ann Burns-Naas -- Developmental immunotoxicity in nonhuman primates / Pauline L. Martin and Eberhard Buse -- Alternative animal models for immunomodulation and immunotoxicity / Peter J. Bugelski -- Animal models for preclinical comparative immunogenicity testing / Daniel Wierda -- T cell epitopes and minimization of immunogenicity / Harald Kropshoffer and Thomas Singer -- Bridging immunotoxicology to clinical drug development / Ian Gourley and Jacques Descotes. |
| Record Nr. | UNINA-9910877896003321 |
| Hoboken, N.J., : Wiley, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
