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Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
Autore Flower Darren R
Edizione [1st edition]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Descrizione fisica 1 online resource (314 p.)
Disciplina 572
615/.3720285
Soggetto topico Immunoinformatics
Vaccines - Design - Data processing
ISBN 1-281-93944-7
9786611939441
0-470-69983-3
0-470-69982-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines
Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity
The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome
Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases
Protein sequence databases
Record Nr. UNINA-9910144096903321
Flower Darren R  
Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
Bioinformatics for vaccinology [[electronic resource] /] / Darren R. Flower
Autore Flower Darren R
Edizione [1st edition]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Descrizione fisica 1 online resource (314 p.)
Disciplina 572
615/.3720285
Soggetto topico Immunoinformatics
Vaccines - Design - Data processing
ISBN 1-281-93944-7
9786611939441
0-470-69983-3
0-470-69982-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines
Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity
The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome
Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases
Protein sequence databases
Record Nr. UNINA-9910830214103321
Flower Darren R  
Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Bioinformatics for vaccinology / / Darren R. Flower
Bioinformatics for vaccinology / / Darren R. Flower
Autore Flower Darren R
Edizione [1st edition]
Pubbl/distr/stampa Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Descrizione fisica 1 online resource (314 p.)
Disciplina 615/.3720285
Soggetto topico Immunoinformatics
Vaccines - Design - Data processing
ISBN 1-281-93944-7
9786611939441
0-470-69983-3
0-470-69982-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bioinformatics for Vaccinology; Contents; Preface; Acknowledgements; Exordium; 1 Vaccines: Their place in history; Smallpox in history; Variolation; Variolation in history; Variolation comes to Britain; Lady Mary Wortley Montagu; Variolation and the Sublime Porte; The royal experiment; The boston connection; Variolation takes hold; The Suttonian method; Variolation in Europe; The coming of vaccination; Edward Jenner; Cowpox; Vaccination vindicated; Louis Pasteur; Vaccination becomes a science; Meister, Pasteur and rabies; A vaccine for every disease; In the time of cholera
Haffkine and choleraBubonic plague; The changing face of disease; Almroth wright and typhoid; Tuberculosis, Koch, and Calmette; Vaccine BCG; Poliomyelitis; Salk and Sabin; Diphtheria; Whooping cough; Many diseases, many vaccines; Smallpox: Endgame; Further reading; 2 Vaccines: Need and opportunity; Eradication and reservoirs; The ongoing burden of disease; Lifespans; The evolving nature of disease; Economics, climate and disease; Three threats; Tuberculosis in the 21 st century; HIV and AIDS; Malaria: Then and now; Influenza; Bioterrorism; Vaccines as medicines
Vaccines and the pharmaceutical industryMaking vaccines; The coming of the vaccine industry; 3 Vaccines: How they work; Challenging the immune system; The threat from bacteria: Robust, diverse, and endemic; Microbes, diversity and metagenomics; The intrinsic complexity of the bacterial threat; Microbes and humankind; The nature of vaccines; Types of vaccine; Carbohydrate vaccines; Epitopic vaccines; Vaccine delivery; Emerging immunovaccinology; The immune system; Innate immunity; Adaptive immunity; The microbiome and mucosal immunity; Cellular components of immunity; Cellular immunity
The T cell repertoireEpitopes: The immunological quantum; The major histocompatibility complex; MHC nomenclature; Peptide binding by the MHC; The structure of the MHC; Antigen presentation; The proteasome; Transporter associated with antigen processing; Class II processing; Seek simplicity and then distrust it; Cross presentation; T cell receptor; T cell activation; Immunological synapse; Signal 1, signal 2, immunodominance; Humoral immunity; Further reading; 4 Vaccines: Data and databases; Making sense of data; Knowledge in a box; The science of -omes and -omics; The proteome
Systems biologyThe immunome; Databases and databanks; The relational database; The XML database; The protein universe; Much data, many databases; What proteins do; What proteins are; The amino acid world; The chiral nature of amino acids; Naming the amino acids; The amino acid alphabet; Defining amino acid properties; Size, charge and hydrogen bonding; Hydrophobicity, lipophilicity and partitioning; Understanding partitioning; Charges, ionization, and pka; Many kinds of property; Mapping the world of sequences; Biological sequence databases; Nucleic acid sequence databases
Protein sequence databases
Record Nr. UNINA-9910876725903321
Flower Darren R  
Chichester, West Sussex, England ; ; Hoboken, NJ, : John Wiley & Sons, 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Computational immunology : applications / / Shyamasree Ghosh
Computational immunology : applications / / Shyamasree Ghosh
Autore Ghosh Shyamasree
Pubbl/distr/stampa Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020]
Descrizione fisica 1 online resource (201 pages)
Disciplina 616.0790285
Soggetto topico Immunoinformatics
ISBN 1-351-02348-9
1-351-02349-7
1-351-02350-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910793933003321
Ghosh Shyamasree  
Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Computational immunology : applications / / Shyamasree Ghosh
Computational immunology : applications / / Shyamasree Ghosh
Autore Ghosh Shyamasree
Pubbl/distr/stampa Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020]
Descrizione fisica 1 online resource (201 pages)
Disciplina 616.0790285
Soggetto topico Immunoinformatics
ISBN 1-351-02348-9
1-351-02349-7
1-351-02350-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910823223703321
Ghosh Shyamasree  
Boca Raton, FL : , : CRC Press, Taylor & Francis Group, , [2020]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2016
Descrizione fisica 1 online resource (212 p.)
Disciplina 616.0790285
Soggetto topico Immunoinformatics
ISBN 0-12-803715-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910797613003321
Amsterdam, [Netherlands] : , : Academic Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
Computational immunology : models and tools / / edited by Josep Bassaganya-Riera ; contributors Vida Abedi [and eighteen others]
Pubbl/distr/stampa Amsterdam, [Netherlands] : , : Academic Press, , 2016
Descrizione fisica 1 online resource (212 p.)
Disciplina 616.0790285
Soggetto topico Immunoinformatics
ISBN 0-12-803715-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910809351003321
Amsterdam, [Netherlands] : , : Academic Press, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Autore Castiglione Filippo <1969, >
Pubbl/distr/stampa Boca Raton : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (284 p.)
Disciplina 616.07/90285
616.0790285
Soggetto topico Immunoinformatics
Immunology - Computer simulation
Research
Computer simulation
Digital computer simulation
ISBN 0-429-16951-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section
Record Nr. UNINA-9910788023303321
Castiglione Filippo <1969, >  
Boca Raton : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Autore Castiglione Filippo <1969, >
Pubbl/distr/stampa Boca Raton : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (284 p.)
Disciplina 616.07/90285
616.0790285
Soggetto topico Immunoinformatics
Immunology - Computer simulation
Research
Computer simulation
Digital computer simulation
ISBN 0-429-16951-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section
Record Nr. UNINA-9910800192103321
Castiglione Filippo <1969, >  
Boca Raton : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Immune system modelling and simulation / / Filippo Castiglione, Institute for Applied Mathematics, National Research Council of Italy, Rome, Italy and Franco Celada, Department of Medicine, Division of Rheumatology, New York University School of
Autore Castiglione Filippo <1969, >
Edizione [1st ed.]
Pubbl/distr/stampa Boca Raton : , : CRC Press, , [2015]
Descrizione fisica 1 online resource (284 p.)
Disciplina 616.07/90285
616.0790285
Soggetto topico Immunoinformatics
Immunology - Computer simulation
Research
Computer simulation
Digital computer simulation
ISBN 0-429-16951-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Cover; Preface; Acknowledgments; Contents; 1: Immunology for Aliens; 2: Aliens for Immunology; 3: C-ImmSim Unveiled; 4: Benchmarks, aka Qualitative Model Validation; 5: Specific Applications; 6: One Last Word; 7: Bibliography; Colour Plate Section
Record Nr. UNINA-9910827595703321
Castiglione Filippo <1969, >  
Boca Raton : , : CRC Press, , [2015]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui