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Immunologia cellulare e molecolare / Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai ; a cura di Silvano Sozzani ; con la collaborazione di Francesco Annunziato ... [et al.] ; illustrazioni di David L. Baker, Alexandra Baker
| Immunologia cellulare e molecolare / Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai ; a cura di Silvano Sozzani ; con la collaborazione di Francesco Annunziato ... [et al.] ; illustrazioni di David L. Baker, Alexandra Baker |
| Autore | Abbas, Abul K. |
| Edizione | [9. ed.] |
| Descrizione fisica | x, 577 p. : ill. ; 28 cm |
| Disciplina | 616.079 |
| Altri autori (Persone) |
Lichtman, Andrew H.
Pillai, Shiv Annunziato, Francesco Sozzani, Silvano Baker, David L Baker, Alexandra |
| Soggetto topico |
Immunology
Immune system - Pathophysiology |
| ISBN | 9788821447372 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | ita |
| Titolo uniforme | |
| Record Nr. | UNISALENTO-991003793849707536 |
Abbas, Abul K.
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| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Tumor ablation : effects on systemic and local anti-tumor immunity and on other tumor-microenvironment / / Yona Keisari, editor
| Tumor ablation : effects on systemic and local anti-tumor immunity and on other tumor-microenvironment / / Yona Keisari, editor |
| Autore | Keisari Yona |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht ; ; New York, : Springer, 2012, c2013 |
| Descrizione fisica | 1 online resource (160 p.) |
| Disciplina | 616.9940632 |
| Collana | The tumor microenvironment |
| Soggetto topico |
Cancer - Thermotherapy
Immune system - Pathophysiology |
| ISBN |
1-283-63399-X
9786613946447 94-007-4694-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Preface; Contents; Chapter 1 Effect of Chemotherapy on the Tumor Microenvironment and Anti-tumor Immunity; 1.1 Introduction; 1.2 Mechanisms of Cell Death Induced by Anti-cancer Therapy; 1.2.1 Apoptosis; 1.2.2 Non-apoptotic Cell Death; 1.2.3 Morphological vs Functional Classification of Cell Death; 1.3 Immunogenicity of Cell Death; 1.4 Biochemical Features of Immunogenic Cell Death; 1.4.1 Calreticulin Exposure; 1.4.2 Heat Shock Proteins (HSPs); 1.4.3 HMGB1 and TLR Interactions; 1.4.4 ATP Release and Activation of the NLRP3 Inflammasome; 1.4.5 Autophagy-Dependent Immune Responses
1.5 Effects of Chemotherapy on the Immune System1.5.1 Immune-Suppressive Effects; 1.5.1.1 Lymphopenia; 1.5.1.2 Non-immunogenic Cell Death; 1.5.2 Immune-Stimulatory Effects; 1.5.2.1 Enhanced Antigen Delivery and Presentation; 1.5.2.2 Homeostatic Proliferation; 1.5.2.3 Regulatory T Cells; 1.5.2.4 Myeloid Derived Suppressor Cells (MDSCs); 1.5.2.5 DNA-Damage Response and Activation of the Innate Immune System; 1.5.2.6 Gemcitabine; 1.5.2.7 5-Fluorouracil (5FU); 1.5.3 Immune-Modulatory Effects of Targeted Agents; 1.5.3.1 Imatinib; 1.5.3.2 Sunitinib and Sorafenib; 1.6 Conclusion; References Chapter 2 Hyperthermia, the Tumor Microenvironment and Immunity2.1 Introduction; 2.2 Hyperthermia; 2.2.1 Fever Range Heating (FRH); 2.2.2 Hyperthermia Range Heating; 2.2.3 Ablation Range Hyperthermia; 2.3 Conclusions; References; Chapter 3 Radiofrequency Ablation in Cancer Therapy: Tuning in to in situ Tumor Vaccines; 3.1 Introduction; 3.2 RFA Techniques/Parameters and Tumor Cell Death; 3.2.1 Direct Effects; 3.2.2 Indirect Effects; 3.3 Release of Immune-Mediating Factors and `Immunogenic' Cell Death; 3.3.1 Release of Tumor-Antigens; 3.3.2 Release of Immune Stimulating Mediators 3.4 Induction of Immune Responses by RFA: The Tumor Microenvironment3.4.1 Antigen Presentation after Radio Frequency Ablation; 3.4.2 Immunity after Radiofrequency Ablation; 3.4.3 Regulation after Radiofrequency Ablation; 3.5 RFA Combinational Strategies; 3.5.1 Tumor Cytotoxicity; 3.5.2 Immunotherapy; 3.5.2.1 Stimulation of Antigen Presentation; 3.5.2.2 Stimulation of T Cell Reactivity; 3.6 Conclusions and Future Perspective; References; Chapter 4 High Intensity Focused Ultrasound (HIFU) Ablation; 4.1 History of HIFU Tumor Ablation; 4.2 Physical Principles of HIFU Ablation 4.3 Technical Aspects of HIFU Ablation4.4 Direct Thermal and Non-thermal Effects on the Tumor; 4.5 Thermal Effects on Tumor Vasculature; 4.6 Indirect Effects on the Tumor; 4.7 HIFU-Induced Antitumor Immune Response; 4.8 Conclusions; References; Chapter 5 The Interrelationship Between Cryoablation, the Immune Response and the Tumor Microenvironment: Stimulatory and Suppressive Effects; 5.1 Introduction; 5.2 Clinical Use of Cryoablation in Cancer; 5.3 Anecdotal Evidence of Immune Response to Cryoablation; 5.4 How Does Cryoablation Kill Tumors?; 5.4.1 Direct Cellular Injury 5.4.2 Indirect Cellular Injury |
| Record Nr. | UNINA-9910437616203321 |
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Keisari Yona
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| Dordrecht ; ; New York, : Springer, 2012, c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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