Antibody fc [[electronic resource]] : linking adaptive and innate immunity / / Margaret E. Ackerman, Falk Nimmerjahn |
Autore | Ackerman Margaret E |
Pubbl/distr/stampa | London, : Academic Press, c2014 |
Descrizione fisica | 1 online resource (376 p.) |
Disciplina | 616.07/93 |
Altri autori (Persone) | NimmerjahnFalk |
Soggetto topico |
Fc receptors
Immune response Anti-antibodies |
Soggetto genere / forma | Electronic books. |
ISBN | 0-12-394818-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Antibody Fc: Linking Adaptive and Innate Immunity; Copyright Page; Contents; List of Contributors; 1. EFFECTOR MECHANISMS; 1 Antibody-Dependent Cellular Cytotoxicity (ADCC); Brief History of ADCC; Effector Cells; Receptors Involved; Mechanisms of ADCC; Recognition of the Target Cell and Cross-Linking of the Fc Receptor on the Effector Cell; Downstream Signals in the Effector Cell; Mechanisms of Killing; The Perforin/Granzyme Cell Death Pathway; The FAS-L Pathway; The ROS/ROI Pathway; ADCC Assays in Relation to Killing Mechanisms; ADCC in Monoclonal Antibody Therapy of Cancer
Versatility of Monoclonal Antibodies as Platforms for Cancer TherapyEvidence for ADCC in Cancer Therapy; ADCC in Infectious Disease: A Correlate of Protection?; Studies of Herpes Simplex Virus; Studies of Human and Simian Immunodeficiency Virus; Ongoing Debate and a Possible Consensus; Rational Modification of ADCC Activity; Enhancing the Link between ADCC and Adaptive Immunity; Perspectives: Future Directions; Acknowledgments; References; 2 Antibody-Dependent Cellular Phagocytosis and Its Impact on Pathogen Control; Introduction; Phagocytic Cells and Their Fcγ Receptors Various Receptors for IgGDifferential Expression of Fcγ Receptors on Phagocytic Cells; Fcγ Receptor-Mediated Phagocytosis by Phagocytes; Signaling by Activating FcγRs; Regulation of FcR Signals; Phagosome Maturation; Role of FcγR-Mediated Phagocytosis for Pathogen Uptake, Cellular Localization, and Pathogen Control; Bacteria; Avoiding Uptake into Phagocytes; Establishing an Intracellular Niche; Evasion Strategy of Bacteria: Proteolytic Degradation of Antibodies; Viruses; Targeting of Viruses to FcRs; Antibody-Dependent Enhancement of Infection; FcR-Mediated Uptake of Parasites and Fungi Leishmania-Specific Antibodies Can Shift the Balance between Th1 and Th2 ResponsesToxoplasma is Targeted to Lysosomes in the Presence of Specific Antibody; Antibody-Mediated Phagocytosis of Invasive Fungi; Concluding Remarks; References; 3 Interactions Between the Complement System and Fcγ Receptors; Preliminary Comments; Complement Fragment C3b Mediates Binding of IgG Immune Complexes to Primate Erythrocytes: Immune Adherence; Historical Perspective; Modern Times and Mechanisms: CR1 is Removed from Erythrocytes Complement Fragment C3d Mediates Binding of Substrates to CR2 on B Cells: Antigen Trafficking and Its Significance in HIV D...Similarities and Differences between CR1 and CR2; The Shuttle Mechanism: CR2 and Antigen Presentation; CR1, CR2, and AIDS; A Clue to a Mechanism: Lessons Learned from Dendritic Cells; Cooperation/Synergy between Fcγ Receptors and Complement Receptors on Effector Cells; In Vivo Studies of the Clearance of Opsonized Erythrocytes; In Vitro Evidence for Synergy between Fcγ Receptors and Complement Receptors; Interaction between FcγRIII and CR3; C3b-IgG as a Superopsonin Interaction between FcγR and Complement: Cancer Models |
Record Nr. | UNINA-9910452543403321 |
Ackerman Margaret E | ||
London, : Academic Press, c2014 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Antimicrobial immune response / / edited by Maria Del Mar Ortega-Villaizan, Veronica Chico |
Pubbl/distr/stampa | London, England : , : IntechOpen, , [2021] |
Descrizione fisica | 1 online resource (100 pages) |
Disciplina | 615.792 |
Soggetto topico |
Anti-infective agents
Immune response |
ISBN | 1-83968-783-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910586671503321 |
London, England : , : IntechOpen, , [2021] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , 2015 |
Descrizione fisica | 1 online resource (364 p.) |
Disciplina | 616.07/9 |
Soggetto topico |
Autophagic vacuoles
Immune response |
ISBN |
1-118-67773-0
1-118-67755-2 1-118-67771-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Autophagy and immunity / Xu Liu and Daniel J. Klionsky -- Techniques for studying autophagy / Isei Tanida and Masato Koike -- Role of autophagy in DNA virus infections in vivo / Xionan Dong and Beth Levine -- Studying RNA viruses and autophagy in vivo / Mehrdad Alirezaei and J. Lindsay Whitton -- Autophagy and picornavirus infection / Tom Wileman, Zhigang Zhou, Matthew Whelband, Eleanor Cottam, Stephen Berryman, Terry Jackson, and Rebecca Roberts -- Flaviviruses and autophagy / Tristan X. Jordan and Glenn Randall -- Autophagy : a home remodeler for Hepatitis C virus / Marine L.B. Hillaire, Elodie Decembre, and Marlene Dreux -- Modulating autophagy to cure Human Immunodeficiency Virus type-1 / Stephen A. Spector and Grant R. Campbell -- Autophagy in the infected cell : insights from pathogenic bacteria / Andrea Sirianni and Serge Mostowy -- Rab proteins in autophagy: streptococcus model / Ichiro Nakagawa -- Helicobacter pylori infection control by autophagy / Laura K. Greenfield, Frances Dang, and Nicola L. Jones -- Interactions between salmonella and the autophagy system / Teresa L.M. Thurston and David W. Holden -- Host factors that recruit autophagy as defense against toxoplasma gondii / Carlos S. Subauste -- Mycobacterium tuberculosis and the autophagic pathway / Gabriela María Recalde and María Isabel Colombo -- Autophagy enhances the efficacy of BCG vaccine / Arshad Khan, Christopher R. Singh, Emily Soudani, Pearl Bakhru, Sankaralingam Saikolappan, Jeffrey D. Cirillo, N. Tony Eissa, Subramanian Dhandayuthapani, and Chinnaswamy Jagannath -- Autophagy's contribution to innate and adaptive immunity : an overview / Christina Bell, Michel Desjardins, Pierre Thibault, and Kerstin Radtke -- Autophagy in immune responses to viruses / Christophe Viret and Mathias Faure -- Processing and MHC presentation of antigens after autophagy-assisted endocytosis, exocytosis and cytoplasm degradation / Christian Münz. |
Record Nr. | UNINA-9910140485703321 |
Hoboken, New Jersey : , : Wiley Blackwell, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Hoboken, New Jersey : , : Wiley Blackwell, , 2015 |
Descrizione fisica | 1 online resource (364 p.) |
Disciplina | 616.07/9 |
Soggetto topico |
Autophagic vacuoles
Immune response |
ISBN |
1-118-67773-0
1-118-67755-2 1-118-67771-4 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Autophagy and immunity / Xu Liu and Daniel J. Klionsky -- Techniques for studying autophagy / Isei Tanida and Masato Koike -- Role of autophagy in DNA virus infections in vivo / Xionan Dong and Beth Levine -- Studying RNA viruses and autophagy in vivo / Mehrdad Alirezaei and J. Lindsay Whitton -- Autophagy and picornavirus infection / Tom Wileman, Zhigang Zhou, Matthew Whelband, Eleanor Cottam, Stephen Berryman, Terry Jackson, and Rebecca Roberts -- Flaviviruses and autophagy / Tristan X. Jordan and Glenn Randall -- Autophagy : a home remodeler for Hepatitis C virus / Marine L.B. Hillaire, Elodie Decembre, and Marlene Dreux -- Modulating autophagy to cure Human Immunodeficiency Virus type-1 / Stephen A. Spector and Grant R. Campbell -- Autophagy in the infected cell : insights from pathogenic bacteria / Andrea Sirianni and Serge Mostowy -- Rab proteins in autophagy: streptococcus model / Ichiro Nakagawa -- Helicobacter pylori infection control by autophagy / Laura K. Greenfield, Frances Dang, and Nicola L. Jones -- Interactions between salmonella and the autophagy system / Teresa L.M. Thurston and David W. Holden -- Host factors that recruit autophagy as defense against toxoplasma gondii / Carlos S. Subauste -- Mycobacterium tuberculosis and the autophagic pathway / Gabriela María Recalde and María Isabel Colombo -- Autophagy enhances the efficacy of BCG vaccine / Arshad Khan, Christopher R. Singh, Emily Soudani, Pearl Bakhru, Sankaralingam Saikolappan, Jeffrey D. Cirillo, N. Tony Eissa, Subramanian Dhandayuthapani, and Chinnaswamy Jagannath -- Autophagy's contribution to innate and adaptive immunity : an overview / Christina Bell, Michel Desjardins, Pierre Thibault, and Kerstin Radtke -- Autophagy in immune responses to viruses / Christophe Viret and Mathias Faure -- Processing and MHC presentation of antigens after autophagy-assisted endocytosis, exocytosis and cytoplasm degradation / Christian Münz. |
Record Nr. | UNINA-9910819421303321 |
Hoboken, New Jersey : , : Wiley Blackwell, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
Drug discovery today Disease mechanisms |
Pubbl/distr/stampa | [Oxford], : Elsevier, ©2004-[2013] |
Descrizione fisica | 1 online resource |
Soggetto topico |
Drug development
Drugs - Design Cardiovascular system - Diseases Immune response Nervous system - Diseases Physiology, Pathological Pathology, Molecular Pathology, Cellular Disease - etiology Drug Therapy Drug Design |
Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
ISSN | 1740-6765 |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti | Disease mechanisms |
Record Nr. | UNISA-996216406603316 |
[Oxford], : Elsevier, ©2004-[2013] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. di Salerno | ||
|
Drug discovery today Disease mechanisms |
Pubbl/distr/stampa | [Oxford], : Elsevier, ©2004-[2013] |
Descrizione fisica | 1 online resource |
Soggetto topico |
Drug development
Drugs - Design Cardiovascular system - Diseases Immune response Nervous system - Diseases Physiology, Pathological Pathology, Molecular Pathology, Cellular Disease - etiology Drug Therapy Drug Design |
Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
ISSN | 1740-6765 |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Altri titoli varianti | Disease mechanisms |
Record Nr. | UNINA-9910143542803321 |
[Oxford], : Elsevier, ©2004-[2013] | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The effect of dietary probiotics on immune and gastrointestinal function ... annual report |
Pubbl/distr/stampa | Washington, D.C., : U.S. Dept. of Agriculture, Agricultural Research Service |
Descrizione fisica | : HTML files |
Disciplina | 616 |
Soggetto topico |
Probiotics
Immune response Gastrointestinal system - Microbiology Gastrointestinal system - Diseases - Prevention |
Soggetto genere / forma | Periodicals. |
Formato | Materiale a stampa |
Livello bibliografico | Periodico |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910698664103321 |
Washington, D.C., : U.S. Dept. of Agriculture, Agricultural Research Service | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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Herd immunity for COVID-19 |
Pubbl/distr/stampa | [Washington, D.C.] : , : GAO - Science, Technology Assessment, and Analytics, , 2020 |
Descrizione fisica | 1 online resource (2 unnumbered pages) : color illustrations |
Collana | Science & tech spotlight |
Soggetto topico |
COVID-19 (Disease) - Prevention
COVID-19 (Disease) - Vaccination COVID-19 (Disease) - Transmission Immune response Herd immunity |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Record Nr. | UNINA-9910713619603321 |
[Washington, D.C.] : , : GAO - Science, Technology Assessment, and Analytics, , 2020 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks |
Pubbl/distr/stampa | Washington, DC, : ASM Press, c2011 |
Descrizione fisica | 1 online resource (700 p.) |
Disciplina |
616.07/9
616.90479 |
Altri autori (Persone) |
KaufmannS. H. E (Stefan H. E.)
RouseBarry T SacksDavid Lawrence |
Soggetto topico |
Immune response
Infection |
ISBN |
1-68367-119-8
1-283-03446-8 9786613034465 1-55581-687-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Contributors; Preface; The Immune Response to Infection: Introduction; SECTION I: HOST DEFENSE: GENERAL; SECTION II: THE PATHOGENS; SECTION III: INNATE IMMUNITY TO MICROBIAL INFECTIONS; SECTION IV: ACQUIRED IMMUNITY TO MICROBIAL INFECTIONS; SECTION V: PATHOLOGY AND PATHOGENESIS; SECTION VI: EVASION AND SUPPRESSION OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VII: GENETICS OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VIII: AUTOIMMUNITY AND CANCER; SECTION IX: IMMUNE INTERVENTION; SECTION X: THE MAJOR KILLERS (CLINICS, EPIDEMIOLOGY, AND IMMUNE PARAMETERS); Index |
Record Nr. | UNINA-9910574098003321 |
Washington, DC, : ASM Press, c2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|
The immune response to infection [[electronic resource] /] / edited by Stefan H.E. Kaufmann, Barry T. Rouse, David L. Sacks |
Pubbl/distr/stampa | Washington, DC, : ASM Press, c2011 |
Descrizione fisica | 1 online resource (700 p.) |
Disciplina |
616.07/9
616.90479 |
Altri autori (Persone) |
KaufmannS. H. E (Stefan H. E.)
RouseBarry T SacksDavid Lawrence |
Soggetto topico |
Immune response
Infection |
ISBN |
1-68367-119-8
1-283-03446-8 9786613034465 1-55581-687-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Contents; Contributors; Preface; The Immune Response to Infection: Introduction; SECTION I: HOST DEFENSE: GENERAL; SECTION II: THE PATHOGENS; SECTION III: INNATE IMMUNITY TO MICROBIAL INFECTIONS; SECTION IV: ACQUIRED IMMUNITY TO MICROBIAL INFECTIONS; SECTION V: PATHOLOGY AND PATHOGENESIS; SECTION VI: EVASION AND SUPPRESSION OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VII: GENETICS OF THE ANTIMICROBIAL HOST RESPONSE; SECTION VIII: AUTOIMMUNITY AND CANCER; SECTION IX: IMMUNE INTERVENTION; SECTION X: THE MAJOR KILLERS (CLINICS, EPIDEMIOLOGY, AND IMMUNE PARAMETERS); Index |
Record Nr. | UNINA-9910830328203321 |
Washington, DC, : ASM Press, c2011 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
|