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Antibody fc [[electronic resource]] : linking adaptive and innate immunity / / Margaret E. Ackerman, Falk Nimmerjahn
Antibody fc [[electronic resource]] : linking adaptive and innate immunity / / Margaret E. Ackerman, Falk Nimmerjahn
Autore Ackerman Margaret E
Pubbl/distr/stampa London, : Academic Press, c2014
Descrizione fisica 1 online resource (376 p.)
Disciplina 616.07/93
Altri autori (Persone) NimmerjahnFalk
Soggetto topico Fc receptors
Immune response
Anti-antibodies
Soggetto genere / forma Electronic books.
ISBN 0-12-394818-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front Cover; Antibody Fc: Linking Adaptive and Innate Immunity; Copyright Page; Contents; List of Contributors; 1. EFFECTOR MECHANISMS; 1 Antibody-Dependent Cellular Cytotoxicity (ADCC); Brief History of ADCC; Effector Cells; Receptors Involved; Mechanisms of ADCC; Recognition of the Target Cell and Cross-Linking of the Fc Receptor on the Effector Cell; Downstream Signals in the Effector Cell; Mechanisms of Killing; The Perforin/Granzyme Cell Death Pathway; The FAS-L Pathway; The ROS/ROI Pathway; ADCC Assays in Relation to Killing Mechanisms; ADCC in Monoclonal Antibody Therapy of Cancer
Versatility of Monoclonal Antibodies as Platforms for Cancer TherapyEvidence for ADCC in Cancer Therapy; ADCC in Infectious Disease: A Correlate of Protection?; Studies of Herpes Simplex Virus; Studies of Human and Simian Immunodeficiency Virus; Ongoing Debate and a Possible Consensus; Rational Modification of ADCC Activity; Enhancing the Link between ADCC and Adaptive Immunity; Perspectives: Future Directions; Acknowledgments; References; 2 Antibody-Dependent Cellular Phagocytosis and Its Impact on Pathogen Control; Introduction; Phagocytic Cells and Their Fcγ Receptors
Various Receptors for IgGDifferential Expression of Fcγ Receptors on Phagocytic Cells; Fcγ Receptor-Mediated Phagocytosis by Phagocytes; Signaling by Activating FcγRs; Regulation of FcR Signals; Phagosome Maturation; Role of FcγR-Mediated Phagocytosis for Pathogen Uptake, Cellular Localization, and Pathogen Control; Bacteria; Avoiding Uptake into Phagocytes; Establishing an Intracellular Niche; Evasion Strategy of Bacteria: Proteolytic Degradation of Antibodies; Viruses; Targeting of Viruses to FcRs; Antibody-Dependent Enhancement of Infection; FcR-Mediated Uptake of Parasites and Fungi
Leishmania-Specific Antibodies Can Shift the Balance between Th1 and Th2 ResponsesToxoplasma is Targeted to Lysosomes in the Presence of Specific Antibody; Antibody-Mediated Phagocytosis of Invasive Fungi; Concluding Remarks; References; 3 Interactions Between the Complement System and Fcγ Receptors; Preliminary Comments; Complement Fragment C3b Mediates Binding of IgG Immune Complexes to Primate Erythrocytes: Immune Adherence; Historical Perspective; Modern Times and Mechanisms: CR1 is Removed from Erythrocytes
Complement Fragment C3d Mediates Binding of Substrates to CR2 on B Cells: Antigen Trafficking and Its Significance in HIV D...Similarities and Differences between CR1 and CR2; The Shuttle Mechanism: CR2 and Antigen Presentation; CR1, CR2, and AIDS; A Clue to a Mechanism: Lessons Learned from Dendritic Cells; Cooperation/Synergy between Fcγ Receptors and Complement Receptors on Effector Cells; In Vivo Studies of the Clearance of Opsonized Erythrocytes; In Vitro Evidence for Synergy between Fcγ Receptors and Complement Receptors; Interaction between FcγRIII and CR3; C3b-IgG as a Superopsonin
Interaction between FcγR and Complement: Cancer Models
Record Nr. UNINA-9910452543403321
Ackerman Margaret E  
London, : Academic Press, c2014
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Antimicrobial immune response / / edited by Maria Del Mar Ortega-Villaizan, Veronica Chico
Antimicrobial immune response / / edited by Maria Del Mar Ortega-Villaizan, Veronica Chico
Pubbl/distr/stampa London, England : , : IntechOpen, , [2021]
Descrizione fisica 1 online resource (100 pages)
Disciplina 615.792
Soggetto topico Anti-infective agents
Immune response
ISBN 1-83968-783-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910586671503321
London, England : , : IntechOpen, , [2021]
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Antimicrobial Resistance and Antibiotics Usage in Livestock : Why Prevention Must Start on the Farm / / edited by Benno ter Kuile
Antimicrobial Resistance and Antibiotics Usage in Livestock : Why Prevention Must Start on the Farm / / edited by Benno ter Kuile
Autore ter Kuile Benno
Edizione [1st ed. 2025.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
Descrizione fisica 1 online resource (177 pages)
Disciplina 571.9646
616.0795
Collana Biomedical and Life Sciences Series
Soggetto topico Immune response
Pathogenic microorganisms
Veterinary medicine
Public health
Antimicrobial Responses
Veterinary Science
Public Health
ISBN 3-032-04598-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Overview and background; Antimicrobial resistance in the veterinary sector -- Preventive measures to minimise veterinary antibiotic use and their impact on antibiotic resistance -- Consequences of antimicrobial residuals in the environment -- Animal movements and food as driving factors for the spread of antimicrobial resistance -- Fluoroquinolones: Role in Healthcare and Environmental Impact and Resistance Development -- EU laws and regulations as an example of rules for the veterinary application of antimicrobials -- Enforcement of the EU regulations 2019/4 and 2019/6.
Record Nr. UNINA-9911034957303321
ter Kuile Benno  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
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Antimicrobial Resistance: Factors to Findings : Omics and Systems Biology Approaches / / edited by Vijay Soni, Ajay Suresh Akhade
Antimicrobial Resistance: Factors to Findings : Omics and Systems Biology Approaches / / edited by Vijay Soni, Ajay Suresh Akhade
Autore Soni Vijay
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (459 pages)
Disciplina 571.96
616.079
Altri autori (Persone) AkhadeAjay Suresh
Soggetto topico Immunology
Immune response
Pathogenic microorganisms
Bioinformatics
Diseases - Causes and theories of causation
Genomics
Antimicrobial Responses
Computational and Systems Biology
Pathogenesis
ISBN 3-031-65986-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Antimicrobial resistance and factors -- Genomics as a tool to track global AMR -- Meta-transcriptomics to reveal mechanisms of drug action and resistance -- Use of proteomics to study bacterial virulence and AMR -- Metabolomics to understand bacterial and drug metabolism -- Microbiome and AMR: A One Health perspective -- Environmental reservoirs, genomic epidemiology, and mobile genetic elements -- Multiomics approach to control AMR -- Systems biology and AMR -- Host-directed omics approaches to control AMR -- Role of AI and Machine Learning in omics analysis of AMR evolution and surveillance -- Drug discovery and AMR treatments using an omics-based approach -- Future perspectives of omics-systems biology to control AMR: Recommendations and future directions.
Record Nr. UNINA-9910886987103321
Soni Vijay  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2024
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Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson
Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, New Jersey : , : Wiley Blackwell, , 2015
Descrizione fisica 1 online resource (364 p.)
Disciplina 616.07/9
Soggetto topico Autophagic vacuoles
Immune response
ISBN 1-118-67773-0
1-118-67755-2
1-118-67771-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Autophagy and immunity / Xu Liu and Daniel J. Klionsky -- Techniques for studying autophagy / Isei Tanida and Masato Koike -- Role of autophagy in DNA virus infections in vivo / Xionan Dong and Beth Levine -- Studying RNA viruses and autophagy in vivo / Mehrdad Alirezaei and J. Lindsay Whitton -- Autophagy and picornavirus infection / Tom Wileman, Zhigang Zhou, Matthew Whelband, Eleanor Cottam, Stephen Berryman, Terry Jackson, and Rebecca Roberts -- Flaviviruses and autophagy / Tristan X. Jordan and Glenn Randall -- Autophagy : a home remodeler for Hepatitis C virus / Marine L.B. Hillaire, Elodie Decembre, and Marlene Dreux -- Modulating autophagy to cure Human Immunodeficiency Virus type-1 / Stephen A. Spector and Grant R. Campbell -- Autophagy in the infected cell : insights from pathogenic bacteria / Andrea Sirianni and Serge Mostowy -- Rab proteins in autophagy: streptococcus model / Ichiro Nakagawa -- Helicobacter pylori infection control by autophagy / Laura K. Greenfield, Frances Dang, and Nicola L. Jones -- Interactions between salmonella and the autophagy system / Teresa L.M. Thurston and David W. Holden -- Host factors that recruit autophagy as defense against toxoplasma gondii / Carlos S. Subauste -- Mycobacterium tuberculosis and the autophagic pathway / Gabriela María Recalde and María Isabel Colombo -- Autophagy enhances the efficacy of BCG vaccine / Arshad Khan, Christopher R. Singh, Emily Soudani, Pearl Bakhru, Sankaralingam Saikolappan, Jeffrey D. Cirillo, N. Tony Eissa, Subramanian Dhandayuthapani, and Chinnaswamy Jagannath -- Autophagy's contribution to innate and adaptive immunity : an overview / Christina Bell, Michel Desjardins, Pierre Thibault, and Kerstin Radtke -- Autophagy in immune responses to viruses / Christophe Viret and Mathias Faure -- Processing and MHC presentation of antigens after autophagy-assisted endocytosis, exocytosis and cytoplasm degradation / Christian Münz.
Record Nr. UNINA-9910140485703321
Hoboken, New Jersey : , : Wiley Blackwell, , 2015
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson
Autophagy, infection, and the immune response / / edited by William T. Jackson and Michele Swanson
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, New Jersey : , : Wiley Blackwell, , 2015
Descrizione fisica 1 online resource (364 p.)
Disciplina 616.07/9
Soggetto topico Autophagic vacuoles
Immune response
ISBN 1-118-67773-0
1-118-67755-2
1-118-67771-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Autophagy and immunity / Xu Liu and Daniel J. Klionsky -- Techniques for studying autophagy / Isei Tanida and Masato Koike -- Role of autophagy in DNA virus infections in vivo / Xionan Dong and Beth Levine -- Studying RNA viruses and autophagy in vivo / Mehrdad Alirezaei and J. Lindsay Whitton -- Autophagy and picornavirus infection / Tom Wileman, Zhigang Zhou, Matthew Whelband, Eleanor Cottam, Stephen Berryman, Terry Jackson, and Rebecca Roberts -- Flaviviruses and autophagy / Tristan X. Jordan and Glenn Randall -- Autophagy : a home remodeler for Hepatitis C virus / Marine L.B. Hillaire, Elodie Decembre, and Marlene Dreux -- Modulating autophagy to cure Human Immunodeficiency Virus type-1 / Stephen A. Spector and Grant R. Campbell -- Autophagy in the infected cell : insights from pathogenic bacteria / Andrea Sirianni and Serge Mostowy -- Rab proteins in autophagy: streptococcus model / Ichiro Nakagawa -- Helicobacter pylori infection control by autophagy / Laura K. Greenfield, Frances Dang, and Nicola L. Jones -- Interactions between salmonella and the autophagy system / Teresa L.M. Thurston and David W. Holden -- Host factors that recruit autophagy as defense against toxoplasma gondii / Carlos S. Subauste -- Mycobacterium tuberculosis and the autophagic pathway / Gabriela María Recalde and María Isabel Colombo -- Autophagy enhances the efficacy of BCG vaccine / Arshad Khan, Christopher R. Singh, Emily Soudani, Pearl Bakhru, Sankaralingam Saikolappan, Jeffrey D. Cirillo, N. Tony Eissa, Subramanian Dhandayuthapani, and Chinnaswamy Jagannath -- Autophagy's contribution to innate and adaptive immunity : an overview / Christina Bell, Michel Desjardins, Pierre Thibault, and Kerstin Radtke -- Autophagy in immune responses to viruses / Christophe Viret and Mathias Faure -- Processing and MHC presentation of antigens after autophagy-assisted endocytosis, exocytosis and cytoplasm degradation / Christian Münz.
Record Nr. UNINA-9910819421303321
Hoboken, New Jersey : , : Wiley Blackwell, , 2015
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Drug discovery today Disease mechanisms
Drug discovery today Disease mechanisms
Pubbl/distr/stampa [Oxford], : Elsevier, ©2004-[2013]
Descrizione fisica 1 online resource
Soggetto topico Drug development
Drugs - Design
Cardiovascular system - Diseases
Immune response
Nervous system - Diseases
Physiology, Pathological
Pathology, Molecular
Pathology, Cellular
Disease - etiology
Drug Therapy
Drug Design
Soggetto genere / forma Periodical
Fulltext
Internet Resources.
Periodicals.
Soggetto non controllato Pharmacy, Therapeutics, & Pharmacology
ISSN 1740-6765
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Disease mechanisms
Record Nr. UNISA-996216406603316
[Oxford], : Elsevier, ©2004-[2013]
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Drug discovery today Disease mechanisms
Drug discovery today Disease mechanisms
Pubbl/distr/stampa [Oxford], : Elsevier, ©2004-[2013]
Descrizione fisica 1 online resource
Soggetto topico Drug development
Drugs - Design
Cardiovascular system - Diseases
Immune response
Nervous system - Diseases
Physiology, Pathological
Pathology, Molecular
Pathology, Cellular
Disease - etiology
Drug Therapy
Drug Design
Soggetto genere / forma Periodical
Fulltext
Internet Resources.
Periodicals.
ISSN 1740-6765
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Disease mechanisms
Record Nr. UNINA-9910143542803321
[Oxford], : Elsevier, ©2004-[2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The effect of dietary probiotics on immune and gastrointestinal function ... annual report
The effect of dietary probiotics on immune and gastrointestinal function ... annual report
Pubbl/distr/stampa Washington, D.C., : U.S. Dept. of Agriculture, Agricultural Research Service
Descrizione fisica : HTML files
Disciplina 616
Soggetto topico Probiotics
Immune response
Gastrointestinal system - Microbiology
Gastrointestinal system - Diseases - Prevention
Soggetto genere / forma Periodicals.
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910698664103321
Washington, D.C., : U.S. Dept. of Agriculture, Agricultural Research Service
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Emerging Modalities in Mitigation of Antimicrobial Resistance / / edited by Nadeem Akhtar, Kumar Siddharth Singh, Prerna, Dinesh Goyal
Emerging Modalities in Mitigation of Antimicrobial Resistance / / edited by Nadeem Akhtar, Kumar Siddharth Singh, Prerna, Dinesh Goyal
Edizione [1st ed. 2022.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
Descrizione fisica 1 online resource (569 pages)
Disciplina 616.9041
615.329
Soggetto topico Immunology
Immune response
Pathogenic microorganisms
Natural immunity
Biotechnology
Antimicrobial Responses
Innate Immunity
ISBN 3-030-84126-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Antimicrobials in livestock production and its cross-domain dynamics -- 2. Antibiotics and resistance in environment -- 3. Antimicrobials in agriculture and its implications in antimicrobial resistance -- 4. Modern diagnostic tools for rapid detection of multidrug resistance -- 5. The use of antimicrobials in agriculture and socio-economic considerations in a global world -- 6. Epidemiology of microbial infections -- 7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach -- 8. Regulations in antimicrobial drug development: Challenges, and new incentives -- 9. New insights into and updates on antimicrobial agents -- 10. Polyphenols as emerging antimicrobial agents -- 11. Antimicrobial peptides and small molecules as antibiotics substitute -- 12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms -- 13. Antimicrobial resistance: Meaning and developing realization -- 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance -- 15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futures -- 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance -- 17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential -- 18. Nanoparticles as a future alternative against multiple drug resistance -- 19. Nano-cargos boarded defensins to combat multi-drug resistance -- 20. Implementation of nano-vehicles to disguise and fight multi-drug resistance -- 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine -- 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution -- 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance -- 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance -- 25. Nano-Strategies against rising antimicrobial resistance (AMR): Metallic nanoparticles as nano-weapon. .
Record Nr. UNINA-9910522571403321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022
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