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Human herpesvirus 6 : global status / / Stephen Berger
| Human herpesvirus 6 : global status / / Stephen Berger |
| Autore | Berger Stephen |
| Pubbl/distr/stampa | Los Angeles, California : , : Gideon, , 2017 |
| Descrizione fisica | 1 online resource (21 pages) : color illustrations |
| Disciplina | 616.0194 |
| Soggetto topico | Human herpesvirus-6 |
| ISBN | 1-4988-1599-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910164208403321 |
Berger Stephen
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| Los Angeles, California : , : Gideon, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human herpesvirus-6 [[electronic resource] ] : general virology, epidemiology, and clinical pathology / / editors, Gerhard Krueger, Dharam Ablashi
| Human herpesvirus-6 [[electronic resource] ] : general virology, epidemiology, and clinical pathology / / editors, Gerhard Krueger, Dharam Ablashi |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (393 p.) |
| Disciplina | 616.9/101 |
| Altri autori (Persone) |
KruegerG. R. F
AblashiD. V (Dharam V.) |
| Collana | Perspectives in medical virology |
| Soggetto topico |
Human herpesvirus-6
Human herpesvirus-6 infections |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-64168-1
9786610641680 0-08-046128-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; Foreword by Robert Gallo; Foreword by Ronald Glaser and Marshall Williams; Preface; Part I: General Virology; Discovery and Classification of Human Herpesvirus-6 (HHV-6); Discovery; Nomenclature and classification; References; Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6); Introduction; Herpesvirus-6 assembly and maturation; Three-dimensional structure of HHV-6 capsid; Comparison of the HHV-6 cappsid structure with those of other human herpesviruses; Conclusion; References; HHV-6 Genome: Similar and Different; Genome classification and biology
Genomes, cellular tropism and laboratory culture Genome structure and repetitive sequence; Genome rearrangements and relationship to other herpes viruses; Genome composition and general molecular biology; Herpes virus conserved and HHV-6-specific genes; Genomes and HHV-6 strains; Acknowledgements; References; Proteins of HHV-6; Introduction; IE proteins; U16/U17; U53, proteinase; U69, kinase; Cellular homologues; U94, AAV-2 rep homologue; Envelope glycoproteins; U39, gB; U48 and U82, gH and gL; U100, gQ; U47, gO; U11; U14; U27; Perspective; References; Biological Features of HHV-6; Introduction HHV-6 cellular receptor Species specificity; Cellular tropism of HHV-6; Target cells in vitro; Cellular and tissue host range in vivo; Biological effects of HHV-6 on the host cell; Cytopathic effects; Latent infection; Cellular transformation; Immune modulation; Human lymphoid tissue ex vivo: a new model for the study of HHV-6 pathogenesis; Dysregulation of complement activation; References; Part II: Diagnosis and Epidemiology; Strain Variants of HHV-6; Introduction; Epidemiology; Molecular biology; Biological aspects of variants A and B Reactivity of monoclonal antibodies to HHV-6 variants A and BDisease associations of HHV-6A and -6B variants; Roseola infantum; CNS disease; Epilepsy and HHV-6B; Transplantation and HHV-6 variants; HHV-6 (variants A and B) and multiple sclerosis; HHV-6A and chronic fatigue syndrome (CFS); Concluding remarks; References; Serologic Testing for Acute and Chronic Infection; Introduction; Serologic assays; Techniques; Immunofluorescence assays; Enzyme immunoassays; Neutralization assays; HHV-6 antigens involved in serologic testing; Characterization of HHV-6-specific antibodies; Serologic findings Seroprevalence studies Primary infection; Latent infection and reactivations; Central nervous system diseases; Pending questions and perspectives; Acknowledgments; References; Molecular Testing for HHV-6 Infection; Introduction; Primary infection: characteristics and diagnostic considerations; PCR analysis of cell-free body fluids; Reverse transcription PCR analysis; Quantitative PCR analysis of HHV-6 DNA in PBMC or blood; Detection of virus variants; Other assay approaches; Future assay methods; PCR-based assays: general considerations and molecular underpinnings; Commercially available tests General considerations for current molecular assays |
| Record Nr. | UNINA-9910457442803321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human herpesvirus-6 [[electronic resource] ] : general virology, epidemiology, and clinical pathology / / editors, Gerhard Krueger, Dharam Ablashi
| Human herpesvirus-6 [[electronic resource] ] : general virology, epidemiology, and clinical pathology / / editors, Gerhard Krueger, Dharam Ablashi |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; Boston, : Elsevier, c2006 |
| Descrizione fisica | 1 online resource (393 p.) |
| Disciplina | 616.9/101 |
| Altri autori (Persone) |
KruegerG. R. F
AblashiD. V (Dharam V.) |
| Collana | Perspectives in medical virology |
| Soggetto topico |
Human herpesvirus-6
Human herpesvirus-6 infections |
| ISBN |
1-280-64168-1
9786610641680 0-08-046128-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover; Contents; Foreword by Robert Gallo; Foreword by Ronald Glaser and Marshall Williams; Preface; Part I: General Virology; Discovery and Classification of Human Herpesvirus-6 (HHV-6); Discovery; Nomenclature and classification; References; Ultrastructure and Assembly of Human Herpesvirus-6 (HHV-6); Introduction; Herpesvirus-6 assembly and maturation; Three-dimensional structure of HHV-6 capsid; Comparison of the HHV-6 cappsid structure with those of other human herpesviruses; Conclusion; References; HHV-6 Genome: Similar and Different; Genome classification and biology
Genomes, cellular tropism and laboratory culture Genome structure and repetitive sequence; Genome rearrangements and relationship to other herpes viruses; Genome composition and general molecular biology; Herpes virus conserved and HHV-6-specific genes; Genomes and HHV-6 strains; Acknowledgements; References; Proteins of HHV-6; Introduction; IE proteins; U16/U17; U53, proteinase; U69, kinase; Cellular homologues; U94, AAV-2 rep homologue; Envelope glycoproteins; U39, gB; U48 and U82, gH and gL; U100, gQ; U47, gO; U11; U14; U27; Perspective; References; Biological Features of HHV-6; Introduction HHV-6 cellular receptor Species specificity; Cellular tropism of HHV-6; Target cells in vitro; Cellular and tissue host range in vivo; Biological effects of HHV-6 on the host cell; Cytopathic effects; Latent infection; Cellular transformation; Immune modulation; Human lymphoid tissue ex vivo: a new model for the study of HHV-6 pathogenesis; Dysregulation of complement activation; References; Part II: Diagnosis and Epidemiology; Strain Variants of HHV-6; Introduction; Epidemiology; Molecular biology; Biological aspects of variants A and B Reactivity of monoclonal antibodies to HHV-6 variants A and BDisease associations of HHV-6A and -6B variants; Roseola infantum; CNS disease; Epilepsy and HHV-6B; Transplantation and HHV-6 variants; HHV-6 (variants A and B) and multiple sclerosis; HHV-6A and chronic fatigue syndrome (CFS); Concluding remarks; References; Serologic Testing for Acute and Chronic Infection; Introduction; Serologic assays; Techniques; Immunofluorescence assays; Enzyme immunoassays; Neutralization assays; HHV-6 antigens involved in serologic testing; Characterization of HHV-6-specific antibodies; Serologic findings Seroprevalence studies Primary infection; Latent infection and reactivations; Central nervous system diseases; Pending questions and perspectives; Acknowledgments; References; Molecular Testing for HHV-6 Infection; Introduction; Primary infection: characteristics and diagnostic considerations; PCR analysis of cell-free body fluids; Reverse transcription PCR analysis; Quantitative PCR analysis of HHV-6 DNA in PBMC or blood; Detection of virus variants; Other assay approaches; Future assay methods; PCR-based assays: general considerations and molecular underpinnings; Commercially available tests General considerations for current molecular assays |
| Record Nr. | UNINA-9910784594903321 |
| Amsterdam ; ; Boston, : Elsevier, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
