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Herpesviridae / / edited by Joseph Ongrádi
| Herpesviridae / / edited by Joseph Ongrádi |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , [2016] |
| Descrizione fisica | 1 online resource (272 pages) : illustrations |
| Disciplina | 576.6484 |
| Soggetto topico | Herpesviruses |
| ISBN |
953-51-4185-6
953-51-2611-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910169217303321 |
| Rijeka, Croatia : , : IntechOpen, , [2016] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Herpesviridae
| Herpesviridae |
| Pubbl/distr/stampa | London, : BioMed Central, 2010-2014 |
| Soggetto topico |
Herpesviruses
Herpesvirus diseases Herpes Virus Herpesviridae Herpesviridae Infections |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Periodical |
| Soggetto non controllato | Microbiology & Immunology |
| ISSN | 2042-4280 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996213364103316 |
| London, : BioMed Central, 2010-2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Herpesviridae
| Herpesviridae |
| Pubbl/distr/stampa | London, : BioMed Central, 2010-2014 |
| Soggetto topico |
Herpesviruses
Herpesvirus diseases Herpes Virus Herpesviridae Herpesviridae Infections Herpèsvirus Maladies à herpèsvirus |
| Soggetto genere / forma |
Fulltext
Internet Resources. Periodicals. Periodical |
| Soggetto non controllato | Microbiology & Immunology |
| ISSN | 2042-4280 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910140414203321 |
| London, : BioMed Central, 2010-2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Herpesviridae viral structure, life cycle, and infections [[electronic resource] /] / [edited by] Toma R. Gluckman
| Herpesviridae viral structure, life cycle, and infections [[electronic resource] /] / [edited by] Toma R. Gluckman |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina | 614.5/812 |
| Altri autori (Persone) | GluckmanToma R |
| Collana | Virology Research Progress |
| Soggetto topico |
Herpesviruses
Herpesvirus diseases |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60876-921-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910452483403321 |
| Hauppauge, NY, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Herpesviridae viral structure, life cycle, and infections [[electronic resource] /] / [edited by] Toma R. Gluckman
| Herpesviridae viral structure, life cycle, and infections [[electronic resource] /] / [edited by] Toma R. Gluckman |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina | 614.5/812 |
| Altri autori (Persone) | GluckmanToma R |
| Collana | Virology Research Progress |
| Soggetto topico |
Herpesviruses
Herpesvirus diseases |
| ISBN | 1-60876-921-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bioluminescence imaging for herpesvirus studies in vivo / Qiyi Tang, Zhen Zhang, and Hua Zhu -- Herpes virus infection in equid species / R. Paillot ... [et al.] -- Herpesvirus and musculoeskeletal diseases / Robert Álvarez-Lafuente and Benjamín Fernández-Gutiérrez -- Herpesvirus micrornas in infection and cancer / Andrea J. O'Hara and Dirk P. Dittmer -- Asymptomatic alphaherpesvirus reactivation / Randall J. Cohrs -- Do cytomegalovirus or Epstein-Barr virus play a role in periodontitis? / Bjørn Grinde and Ingar Olsen -- Human herpesvirus-6 in transplant organ recipients / Bartlomiej Matlosz et al. -- Gammaherpesviruses and oncogenesis / M. Kudelova and J. Rajcani -- Present focus on HPV virus induced cancer / Viroj Wiwanitkit -- Human herpesvirus-6 and acute liver failure / Irmeli Lautenschlager, Maiju Härmä, and Krister Höckerstedt -- Herpesviruses type 1 (HHV-1), 6 (HH-6) and 7 (HHV-7) role in chronic human diseases / Leite, J.L. ... [et al.] -- Induction of anticardiolipin antibodies associated with human herpesvirus-6 infection / Mitsuo Toyoshima and Yoshihiro Maegaki. |
| Record Nr. | UNINA-9910779647203321 |
| Hauppauge, NY, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Herpesviridae viral structure, life cycle, and infections / / [edited by] Toma R. Gluckman
| Herpesviridae viral structure, life cycle, and infections / / [edited by] Toma R. Gluckman |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hauppauge, NY, : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (297 p.) |
| Disciplina | 614.5/812 |
| Altri autori (Persone) | GluckmanToma R |
| Collana | Virology Research Progress |
| Soggetto topico |
Herpesviruses
Herpesvirus diseases |
| ISBN | 1-60876-921-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bioluminescence imaging for herpesvirus studies in vivo / Qiyi Tang, Zhen Zhang, and Hua Zhu -- Herpes virus infection in equid species / R. Paillot ... [et al.] -- Herpesvirus and musculoeskeletal diseases / Robert Álvarez-Lafuente and Benjamín Fernández-Gutiérrez -- Herpesvirus micrornas in infection and cancer / Andrea J. O'Hara and Dirk P. Dittmer -- Asymptomatic alphaherpesvirus reactivation / Randall J. Cohrs -- Do cytomegalovirus or Epstein-Barr virus play a role in periodontitis? / Bjørn Grinde and Ingar Olsen -- Human herpesvirus-6 in transplant organ recipients / Bartlomiej Matlosz et al. -- Gammaherpesviruses and oncogenesis / M. Kudelova and J. Rajcani -- Present focus on HPV virus induced cancer / Viroj Wiwanitkit -- Human herpesvirus-6 and acute liver failure / Irmeli Lautenschlager, Maiju Härmä, and Krister Höckerstedt -- Herpesviruses type 1 (HHV-1), 6 (HH-6) and 7 (HHV-7) role in chronic human diseases / Leite, J.L. ... [et al.] -- Induction of anticardiolipin antibodies associated with human herpesvirus-6 infection / Mitsuo Toyoshima and Yoshihiro Maegaki. |
| Record Nr. | UNINA-9910809638203321 |
| Hauppauge, NY, : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human herpesviruses HHV-6A, HHV-6B, and HHV-7 : diagnosis and clinical management / / Louis Flamand, Quebec, PQ, Canada [and three others]
| Human herpesviruses HHV-6A, HHV-6B, and HHV-7 : diagnosis and clinical management / / Louis Flamand, Quebec, PQ, Canada [and three others] |
| Autore | Flamand Louis |
| Edizione | [3rd ed.] |
| Pubbl/distr/stampa | Oxford : , : Elsevier, , 2014 |
| Descrizione fisica | 1 online resource (362 p.) |
| Disciplina | 616.9112 2 |
| Soggetto topico | Herpesviruses |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-444-62716-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Human Herpesviruses HHV-6A, HHV-6B, and HHV-7; Copyright Page; Contents; List of Contributors; Foreword by Philip E. Pellett; Foreword by Yoshizo Asano; Dedication; 1 HHV-6A and HHV-6B Officially Classified as Distinct Viruses; Introduction and Classification History; Distinct Epidemiology and Disease Associations; Acknowledgment; References; 2 Practical Diagnostic Procedures for HHV-6A, HHV-6B, and HHV-7; An Overview of Diagnostic Strategies; Objectives; Direct and Indirect Approaches; Specimens; Methods of Direct Diagnosis; Cell Culture; Antigen Detection
Nucleic Acid Detection, Quantitation, and SequencingDetection of DNA by in situ Hybridization; Detection and Quantitation of DNA by PCR and Real-Time PCR; Detection and Quantitation of Transcripts by RT-PCR; Nucleotide Sequencing; Differential Diagnosis of HHV-6A and HHV-6B Infection; Antiviral Susceptibility Assays; Serologic Methods; Techniques; Viral Antigens Used for Serologic Testing; Characterization of Specific Antibodies; Indications and Findings; Primary Infection; Chronic Infection and Reactivations; Chromosomal Integration; Epidemiology; Therapeutic Follow-Up Conclusions: Practical Management of DiagnosisReferences; 3 Pathologic Features of HHV-6A, HHV-6B, and HHV-7 Infection (Light and Electron Microscopy); Introduction; Viral Infection and Pathogenesis; Morphogenesis of Cell and Tissue Lesions; Anatomic (Systemic) Pathology of Tissues and Organs; Diagnostic Criteria; Pathologic Lesions in Primary Infection; Viral Persistence and Chromosomal Integration; Pathologic Lesions in Reactivation and Endogenous Reinfection; Morphology of Organ Systems in Reactivated Infections; Cardiovascular System; Respiratory System; Gastrointestinal System Liver, Biliary System, and PancreasHematopoietic and Lymphatic System; Endocrine System; Urogenital System; Skin and Soft Tissues; Central Nervous System; Autoimmune Disorders; Virus Interactions; References; 4 HHV-6A, HHV-6B, and HHV-7 in Febrile Seizures and Status Epilepticus; Introduction; History of HHV-6, Roseola Infantum, and Febrile Seizures; HHV-6B and Febrile Seizures; HHV-6B and Recurrence of Febrile Seizures; HHV-6A, HHV-6B, and HHV-7 in Children with Febrile Status Epilepticus; HHV-6 and HHV-7 and Temporal Lobe Epilepsy; HHV-6 Encephalitis in Immunocompetent Patients HHV-6 and Limbic Encephalitis in Immunosuppressed PatientsConclusions; References; 5 HHV-6A, HHV-6B, and HHV-7 in Encephalitis; Introduction; General Aspects and Neurotropism of Human Herpesvirus 6A Infection; General Aspects of Human Herpesvirus 6B Infection; Importance of Chromosomally Integrated HHV-6 in Neurological Conditions; Human Herpesvirus 7; Clinical Presentation of HHV-6- or HHV-7-Associated Encephalitis; Encephalitis Following a Primary HHV-6 or HHV-7 Infection in Immunocompetent Individuals; Encephalitis Following Reactivation of HHV-6 or HHV-7 in Immunocompromised Patients Pathology and Pathogenesis |
| Record Nr. | UNISA-996426332603316 |
Flamand Louis
|
||
| Oxford : , : Elsevier, , 2014 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
| Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2010 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.9101
616.99/4019 616.994019 |
| Altri autori (Persone) |
OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict) |
| Soggetto topico |
Oncogenic viruses
Hepatitis viruses Herpesviruses |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-76042-4
9786612760426 981-283-347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis 5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide 2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV 6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV |
| Record Nr. | UNINA-9910456103403321 |
| New Jersey, : World Scientific, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
| Human oncogenic viruses [[electronic resource] /] / editors, Jing-Hsiung James Ou, T. S. Benedict Yen |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2010 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.9101
616.99/4019 616.994019 |
| Altri autori (Persone) |
OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict) |
| Soggetto topico |
Oncogenic viruses
Hepatitis viruses Herpesviruses |
| ISBN |
1-282-76042-4
9786612760426 981-283-347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis 5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide 2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV 6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV |
| Record Nr. | UNINA-9910780891803321 |
| New Jersey, : World Scientific, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Human oncogenic viruses / / editors, Jing-Hsiung James Ou, T. S. Benedict Yen
| Human oncogenic viruses / / editors, Jing-Hsiung James Ou, T. S. Benedict Yen |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | New Jersey, : World Scientific, c2010 |
| Descrizione fisica | 1 online resource (352 p.) |
| Disciplina |
616.9101
616.99/4019 616.994019 |
| Altri autori (Persone) |
OuJ.-H. James <1954-> (Jing-hsiung James)
YenT. S. Benedict <1953-2009.> (Tien-Sze Benedict) |
| Soggetto topico |
Oncogenic viruses
Hepatitis viruses Herpesviruses |
| ISBN |
1-282-76042-4
9786612760426 981-283-347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Contents; Foreword; Preface; Chapter 1 Oncogenic Viruses, Cellular Transformation and Human Cancers Yanyan Zheng and Jing-hsiung James Ou; 1. Introduction and Historical Aspects; 2. Human Oncogenic Viruses; 2.1. Hepatitis B Virus (HBV); 2.2. Hepatitis C Virus (HCV); 2.3. Human Papilloma Virus (HPV); 2.4. Epstein-Barr Virus (EBV); 2.5. Kaposi's Sarcoma-associated Herpesvirus (KSHV); 2.6. Human T-cell Leukemia Virus-1 (HTLV-1); 3. Mechanisms of Virus-induced Cellular Transformation; 3.1. Perturbation of Signaling Pathways; 3.1.1. Mimicking the signaling ligands
3.1.2. Mimicking the cellular signaling receptors3.1.3. Mimicking the intracellular signaling adaptors; 3.1.4. Activation of cell surface receptors; 3.2. Deregulation of the Cell Cycle; 3.2.1. Abrogation of the RB function; 3.2.2. Enhancement of CDK activities; 3.2.3. Targeting of cyclin; 3.3. Escape of Apoptosis; 3.3.1. Inactivation of the "gatekeeper" p53; 3.3.2. Expression of viral version of Bcl-2 (vBcl-2); 3.4. Immortalization of Cells; 3.5. Induction of Genetic Instability; 3.6. Insertional Mutagenesis; 3.7. Induction of Chronic Inflammation; 4. Concluding Remarks; Bibliography Chapter 2 Hepatitis B Virus and Hepatocellular Carcinogenesis T. S. Benedict Yen1. Hepatitis B Virus and Hepatocellular Carcinoma; 2. Biology and Epidemiology of HBV; 3. HBV Virology; 4. Prevention and Treatment of HBV; 5. Mechanisms of HBV Carcinogenesis; 5.1. Overview; 5.2. HBV-specific Factors; 5.2.1. X protein; 5.2.1.1. Function of X protein in the HBV life cycle; 5.2.1.2. Effect of X protein on transcription; 5.2.1.3. Effect of X protein on viral replication; 5.2.1.4. X protein and DDB1; 5.2.1.5. X-protein carcinogenesis; 5.2.2. Other viral proteins potentially involved in carcinogenesis 5.2.2.1. Truncated MSP5.2.2.2. preS2 mutants; 5.2.2.3. Core gene mutants; 5.2.3. Insertional mutagenesis; 5.3. Role of Liver Injury and Inflammation; 5.4. Dietary Carcinogens; 5.5. Other Aspects of HBV Oncogenesis; 5.5.1. Role of genotypes; 5.5.2. Role of sex hormones; 6. Summary; Note; References; Chapter 3 Molecular Mechanism of Hepatitis C Virus Carcinogenesis Keigo Machida, Jing-hsiung James Ou and Michael M. C. Lai; 1. Introduction; 2. Molecular Carcinogenesis of HCV; 2.1. Induction of Mutator Phenotype; 2.2. Chromosome Translocation; 2.3. Reactive Oxygen Species (ROS); 2.4. Nitric Oxide 2.5. Inhibition of DNA Damage Repair2.6. Oncogenic Activities of the HCV Core Protein; 2.6.1. TNF-α; 2.6.2. MAPK and AP-1; 2.6.3. NF-κB; 2.6.4. Oxidative stress; 2.6.5. Insulin resistance; 2.6.6. PPARα; 2.6.7. Proteasome activator PA28γ; 2.6.8. SOCS-1; 2.6.9. p53; 2.7. Oncogenic Activities of the HCV NS5A Protein; 3. Other Causative Factors in HCV-associated HCC; 3.1. Chronic Liver Inflammation; 3.2. Alcohol; 4. Endoplasmic Reticulum Stress and HCV Pathogenesis; 5. Gene Expression Profile of HCC; 6. HCV and Lymphomagenesis; 6.1. Induction of IgHypermutation by HCV 6.2. Induction of DNA Translocation between IgGenes and Proto-Oncogenes by HCV |
| Record Nr. | UNINA-9910816046903321 |
| New Jersey, : World Scientific, c2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Herpesviruses
(10)
- Herpesvirus diseases (5)
- Hepatitis viruses (3)
- Oncogenic viruses (3)
- Herpes Virus (2)