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Advanced Therapy for Hepatitis C [[electronic resource]]
Advanced Therapy for Hepatitis C [[electronic resource]]
Autore McCaughan Geoffrey W
Pubbl/distr/stampa Hoboken, : Wiley, 2011
Descrizione fisica 1 online resource (233 p.)
Disciplina 616.3/62306
616.362306
Altri autori (Persone) McHutchisonJohn
PawlotskyJean-Michel
Soggetto topico Antiviral agents
Antiviral Agents - therapeutic use
Antiviral Agents -- therapeutic use
Hepatitis C - therapy
Hepatitis C -- therapy
Hepatitis C - Treatment
Hepatitis C -- Treatment
Hepatitis, Viral, Human
Flaviviridae Infections
Anti-Infective Agents
RNA Virus Infections
Therapeutic Uses
Virus Diseases
Hepatitis
Diseases
Liver Diseases
Pharmacologic Actions
Chemical Actions and Uses
Digestive System Diseases
Antiviral Agents
Hepatitis C
Medicine
Health & Biological Sciences
Gastroenterology
ISBN 1-283-28323-9
9786613283238
1-4443-4634-2
1-4443-4631-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension
18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index
Record Nr. UNINA-9910139591503321
McCaughan Geoffrey W  
Hoboken, : Wiley, 2011
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Advanced therapy for hepatitis C / / edited by Geoffrey W. McCaughan, John G. McHutchison, Jean-Michel Pawlotsky
Advanced therapy for hepatitis C / / edited by Geoffrey W. McCaughan, John G. McHutchison, Jean-Michel Pawlotsky
Edizione [1st ed.]
Pubbl/distr/stampa Chichester, West Sussex, : Wiley-Blackwell, 2012
Descrizione fisica 1 online resource (233 p.)
Disciplina 616.3/62306
Altri autori (Persone) McCaughanGeoffrey W
McHutchisonJ. G
PawlotskyJean-Michel
Soggetto topico Hepatitis C - Treatment
Antiviral agents
ISBN 1-283-28323-9
9786613283238
1-4443-4634-2
1-4443-4631-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension
18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index
Record Nr. UNINA-9910809498803321
Chichester, West Sussex, : Wiley-Blackwell, 2012
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih
Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih
Pubbl/distr/stampa Singapore ; ; Hackensack, NJ, : World Scientific, c2013
Descrizione fisica 1 online resource (415 p.)
Disciplina 616.3/623
Altri autori (Persone) ShihChiaho
Soggetto topico Chronic diseases
Hepatitis B - Pathophysiology
Hepatitis C - Pathophysiology
Hepatitis C - Treatment
Soggetto genere / forma Electronic books.
ISBN 1-283-85067-2
981-4299-79-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface; Foreword; Contents; Contributors; Hepatitis B Virus; Chapter 1 Natural Course of Chronic Hepatitis B Virus Infection Chia-Ming Chu and Yun-Fan Liaw; Introduction; Epidemiology of Chronic HBV Infection; Clinical Presentation; Phases of Chronic HBV Infection; Immune Tolerant Phase; Immune Clearance Phase; Hepatitis Activity and Acute Hepatitis Flares (HBeAg-positive Chronic Hepatitis) during Immune Clearance Phase; HBeAg to anti-HBe Seroconversion; HBeAg Persistence and Its Outcome; Inactive/Residual Phase; Spontaneous HBsAg Seroclearance; Reactivation of Hepatitis B; HBeAg Reversion
HBeAg-Negative Chronic HepatitisConcurrent Viral Superinfection as Part of Natural Course; Hepatitic C Virus; Hepatitis D Virus; Human Immunodeficiency Virus; Sequelae and Mortality; Cirrhosis and Contributing Factors; Hepatic Decompensation and Mortality; HCC and Contributing Factors; Survival of Cirrhosis; Conclusion; References; Chapter 2 Immune Response and Viral Hepatitis B David R. Milich; Introduction; Serology of Acute and Chronic HBV Infections; The PreS Envelope Antigens; Increased Complexity of the Serology of Chronic HBV Infection
Human T Cell Responses in Acute and Chronic HBV InfectionCD4 + Th Cell Response; CD8 + CTL Response; Innate Immunity to HBV; Mechanisms of Liver Injury and Clearance; Transgenic Models of Immune-mediated Liver Injury; HBV Persistence; Tolerogenicity of HBc/HBeAgs; Immune Escape Variants; Manifestations of HBV-Specific T Cell Tolerance; Immunogenetics; Summary; Acknowledgment; References; Chapter 3 Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma Katherine A. McGlynn, Alison A. Evans and W. Thomas London; Introduction; History; Global Prevalence of Chronic HBV Infection
Liver Cancer Incidence, Mortality, and SurvivalDemographic Factors; Age; Sex; Ethnicity; Risk Factors; Aflatoxin; Alcohol; Tobacco; Pesticides; Iron-related Conditions; Endogenous and Exogenous Hormones; Host Susceptibility; Susceptibility to Chronic HBV Infection; Susceptibility to HCC Once Chronic HBV Infection is Established; Viral Factors; Viral Load; Viral Genotype; Viral Mutations; HBV and Other Cancers; Future Directions and Unresolved Issues; References; Chapter 4 Molecular Biology of HBV-related Hepatocellular Carcinoma Amanda J. Hodgson and Betty L. Slagle; Abstract; Introduction
Lessons from Other Tumor VirusesHBV and HCC; A Model for HBV-associated HCC; Immune-mediated Pathogenesis; Early Immune Response to HBV Infection; Immune-mediated Clearance of HBV; Immune Pathogenesis During Chronic Infection; Effect of HBx on Liver Regeneration; Liver Regeneration in HBV Transgenic Mice; Role of Viral Integration in HCC; General Features of HBV Integration; Lessons Learned from the WHV System; HBV Integration in Human HCCs; Potential Oncogenic Properties of HBV Gene Products; PreS1; PreS2 Truncations; Regulatory HBx Protein; HBx and the Cell Cycle
Activation of Signal Transduction Pathways
Record Nr. UNINA-9910464764903321
Singapore ; ; Hackensack, NJ, : World Scientific, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih
Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih
Pubbl/distr/stampa Singapore ; ; Hackensack, NJ, : World Scientific, c2013
Descrizione fisica 1 online resource (415 p.)
Disciplina 616.3/623
Altri autori (Persone) ShihChiaho
Soggetto topico Chronic diseases
Hepatitis B - Pathophysiology
Hepatitis C - Pathophysiology
Hepatitis C - Treatment
ISBN 1-283-85067-2
981-4299-79-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface; Foreword; Contents; Contributors; Hepatitis B Virus; Chapter 1 Natural Course of Chronic Hepatitis B Virus Infection Chia-Ming Chu and Yun-Fan Liaw; Introduction; Epidemiology of Chronic HBV Infection; Clinical Presentation; Phases of Chronic HBV Infection; Immune Tolerant Phase; Immune Clearance Phase; Hepatitis Activity and Acute Hepatitis Flares (HBeAg-positive Chronic Hepatitis) during Immune Clearance Phase; HBeAg to anti-HBe Seroconversion; HBeAg Persistence and Its Outcome; Inactive/Residual Phase; Spontaneous HBsAg Seroclearance; Reactivation of Hepatitis B; HBeAg Reversion
HBeAg-Negative Chronic HepatitisConcurrent Viral Superinfection as Part of Natural Course; Hepatitic C Virus; Hepatitis D Virus; Human Immunodeficiency Virus; Sequelae and Mortality; Cirrhosis and Contributing Factors; Hepatic Decompensation and Mortality; HCC and Contributing Factors; Survival of Cirrhosis; Conclusion; References; Chapter 2 Immune Response and Viral Hepatitis B David R. Milich; Introduction; Serology of Acute and Chronic HBV Infections; The PreS Envelope Antigens; Increased Complexity of the Serology of Chronic HBV Infection
Human T Cell Responses in Acute and Chronic HBV InfectionCD4 + Th Cell Response; CD8 + CTL Response; Innate Immunity to HBV; Mechanisms of Liver Injury and Clearance; Transgenic Models of Immune-mediated Liver Injury; HBV Persistence; Tolerogenicity of HBc/HBeAgs; Immune Escape Variants; Manifestations of HBV-Specific T Cell Tolerance; Immunogenetics; Summary; Acknowledgment; References; Chapter 3 Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma Katherine A. McGlynn, Alison A. Evans and W. Thomas London; Introduction; History; Global Prevalence of Chronic HBV Infection
Liver Cancer Incidence, Mortality, and SurvivalDemographic Factors; Age; Sex; Ethnicity; Risk Factors; Aflatoxin; Alcohol; Tobacco; Pesticides; Iron-related Conditions; Endogenous and Exogenous Hormones; Host Susceptibility; Susceptibility to Chronic HBV Infection; Susceptibility to HCC Once Chronic HBV Infection is Established; Viral Factors; Viral Load; Viral Genotype; Viral Mutations; HBV and Other Cancers; Future Directions and Unresolved Issues; References; Chapter 4 Molecular Biology of HBV-related Hepatocellular Carcinoma Amanda J. Hodgson and Betty L. Slagle; Abstract; Introduction
Lessons from Other Tumor VirusesHBV and HCC; A Model for HBV-associated HCC; Immune-mediated Pathogenesis; Early Immune Response to HBV Infection; Immune-mediated Clearance of HBV; Immune Pathogenesis During Chronic Infection; Effect of HBx on Liver Regeneration; Liver Regeneration in HBV Transgenic Mice; Role of Viral Integration in HCC; General Features of HBV Integration; Lessons Learned from the WHV System; HBV Integration in Human HCCs; Potential Oncogenic Properties of HBV Gene Products; PreS1; PreS2 Truncations; Regulatory HBx Protein; HBx and the Cell Cycle
Activation of Signal Transduction Pathways
Record Nr. UNINA-9910789348703321
Singapore ; ; Hackensack, NJ, : World Scientific, c2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda
Edizione [1st ed.]
Pubbl/distr/stampa London, England : , : Future Medicine Ltd., , [2013]
Descrizione fisica 1 online resource (117 p.)
Disciplina 616.362306
Soggetto topico Hepatitis C - Treatment
Hepatitis C - Chemotherapy
Antiviral agents
ISBN 1-78084-270-8
1-78084-271-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; Foreword. Hepatitis C virus infection: from discovery to eradication; 1. Interferons in clinical trials; 2. Protease inhibitors; 3. NS5A inhibitor: daclatasvir; 4. Toll-like receptor agonists for nonresponders to hepatitis C virus treatment: hope versus promise?; 5. Treatment options in HIV-HCV-coinfected patients; 6. Treatment options for dual hepatitis C/hepatitis B virus coinfection; 7. Hepatitis C virus treatment in patients with metabolic syndrome; 8. Future directions in hepatitis C therapy; Index
Record Nr. UNINA-9910779873003321
London, England : , : Future Medicine Ltd., , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda
Edizione [1st ed.]
Pubbl/distr/stampa London, England : , : Future Medicine Ltd., , [2013]
Descrizione fisica 1 online resource (117 p.)
Disciplina 616.362306
Soggetto topico Hepatitis C - Treatment
Hepatitis C - Chemotherapy
Antiviral agents
ISBN 1-78084-270-8
1-78084-271-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; Foreword. Hepatitis C virus infection: from discovery to eradication; 1. Interferons in clinical trials; 2. Protease inhibitors; 3. NS5A inhibitor: daclatasvir; 4. Toll-like receptor agonists for nonresponders to hepatitis C virus treatment: hope versus promise?; 5. Treatment options in HIV-HCV-coinfected patients; 6. Treatment options for dual hepatitis C/hepatitis B virus coinfection; 7. Hepatitis C virus treatment in patients with metabolic syndrome; 8. Future directions in hepatitis C therapy; Index
Record Nr. UNINA-9910827838803321
London, England : , : Future Medicine Ltd., , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Hepatitis C [[electronic resource] ] : an introductory guide for patients
Hepatitis C [[electronic resource] ] : an introductory guide for patients
Pubbl/distr/stampa [Washington, D.C.] : , : VA Hepatitis C Resource Center Program and Clinical Public Health Programs Office, Veterans Health Administration, U.S. Dept. of Veterans Affairs, , [2008]
Descrizione fisica 18 unnumbered pages : digital, PDF file
Soggetto topico Hepatitis C - Treatment
Hepatitis, Viral - Treatment
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Hepatitis C
Record Nr. UNINA-9910698851403321
[Washington, D.C.] : , : VA Hepatitis C Resource Center Program and Clinical Public Health Programs Office, Veterans Health Administration, U.S. Dept. of Veterans Affairs, , [2008]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Management of hepatitis C [[electronic resource] ] : 2002 : January 1997 through April 2002 : 4,841 citations / / prepared by Kristine M. Scannell, Carolyn C. Willard, Leonard B. Seeff
Management of hepatitis C [[electronic resource] ] : 2002 : January 1997 through April 2002 : 4,841 citations / / prepared by Kristine M. Scannell, Carolyn C. Willard, Leonard B. Seeff
Autore Scannell Kristine
Pubbl/distr/stampa Bethesda, Md. (8600 Rockville Pike) : , : U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Library of Medicine, Reference Section, , [2002]
Descrizione fisica vi, 280 pages : digital, PDF file
Altri autori (Persone) WillardCarolyn
SeeffLeonard B
Collana Current bibliographies in medicine
Soggetto topico Hepatitis C
Hepatitis C - Treatment
Hepatitis C virus
Hepatitis C - diagnosis
Hepatitis C - drug therapy
Hepatitis C - epidemiology
Hepacivirus
Interferon-alpha - therapeutic use
Soggetto genere / forma Bibliography
Bibliographies.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Management of hepatitis C
Record Nr. UNINA-9910695711103321
Scannell Kristine  
Bethesda, Md. (8600 Rockville Pike) : , : U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Library of Medicine, Reference Section, , [2002]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Managing side effects of Hepatitis C treatment [[electronic resource] /] / The VA Hepatitis C Resource Center Program and the National Clinical Public Health Program, Veterans Health Administration, U.S. Department of Veterans Affairs
Managing side effects of Hepatitis C treatment [[electronic resource] /] / The VA Hepatitis C Resource Center Program and the National Clinical Public Health Program, Veterans Health Administration, U.S. Department of Veterans Affairs
Pubbl/distr/stampa [Washington, D.C.] : , : U.S. Dept. of Veterans Affairs, , [2007]
Descrizione fisica 63 pages : digital, PDF file
Soggetto topico Hepatitis C - Treatment
Hepatitis, Viral - Treatment
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti HCRC VA Hepatitis C Resource Centers
Record Nr. UNINA-9910697843403321
[Washington, D.C.] : , : U.S. Dept. of Veterans Affairs, , [2007]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui