Advanced Therapy for Hepatitis C [[electronic resource]] |
Autore | McCaughan Geoffrey W |
Pubbl/distr/stampa | Hoboken, : Wiley, 2011 |
Descrizione fisica | 1 online resource (233 p.) |
Disciplina |
616.3/62306
616.362306 |
Altri autori (Persone) |
McHutchisonJohn
PawlotskyJean-Michel |
Soggetto topico |
Antiviral agents
Antiviral Agents - therapeutic use Antiviral Agents -- therapeutic use Hepatitis C - therapy Hepatitis C -- therapy Hepatitis C - Treatment Hepatitis C -- Treatment Hepatitis, Viral, Human Flaviviridae Infections Anti-Infective Agents RNA Virus Infections Therapeutic Uses Virus Diseases Hepatitis Diseases Liver Diseases Pharmacologic Actions Chemical Actions and Uses Digestive System Diseases Antiviral Agents Hepatitis C Medicine Health & Biological Sciences Gastroenterology |
ISBN |
1-283-28323-9
9786613283238 1-4443-4634-2 1-4443-4631-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension 18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index |
Record Nr. | UNINA-9910139591503321 |
McCaughan Geoffrey W
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Hoboken, : Wiley, 2011 | ||
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Lo trovi qui: Univ. Federico II | ||
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Advanced therapy for hepatitis C / / edited by Geoffrey W. McCaughan, John G. McHutchison, Jean-Michel Pawlotsky |
Edizione | [1st ed.] |
Pubbl/distr/stampa | Chichester, West Sussex, : Wiley-Blackwell, 2012 |
Descrizione fisica | 1 online resource (233 p.) |
Disciplina | 616.3/62306 |
Altri autori (Persone) |
McCaughanGeoffrey W
McHutchisonJ. G PawlotskyJean-Michel |
Soggetto topico |
Hepatitis C - Treatment
Antiviral agents |
ISBN |
1-283-28323-9
9786613283238 1-4443-4634-2 1-4443-4631-8 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Advanced Therapy for Hepatitis C; Contents; Contributors; Preface; Section I Foundations for Understanding Antiviral Therapies in HCV; 1 HCV Replication; 2 Hepatitis C Virus Genotypes; 3 Immune Responses to HCV: Implications for Therapy; 4 Mechanisms of Action of Antiviral Drugs: The Interferons; 5 Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs; 6 Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors; 7 Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors; 8 Measuring Antiviral Responses
Section II Efficacy and Clinical Use of Antiviral Therapies9 Genotype 1: Standard Treatment; 10 Individually Tailored Treatment Strategies in Treatment-naïve Chronic Hepatitis C Genotype 1 Patients; 11 Genotype 1 Relapsers and Non-responders; 12 Standard Therapy for Genotypes 2/3; 13 Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3; 14 Genotypes 2 and 3 Relapse and Non-response; 15 Hepatitis C Genotype 4 Therapy: Progress and Challenges; 16 Antivirals in Acute Hepatitis C; 17 Antivirals in Cirrhosis and Portal Hypertension 18 Treatment of Recurrent Hepatitis C Following Liver Transplantation19 Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations; 20 Cytopenias: How they Limit Therapy and Potential Correction; 21 The Problem of Insulin Resistance and its Effect on Therapy; 22 HIV and Hepatitis C Co-infection; 23 HCV and Racial Differences; 24 HCV and the Pediatric Population; 25 New Horizons: IL28, Direct-acting Antiviral Therapy for HCV; Index |
Record Nr. | UNINA-9910809498803321 |
Chichester, West Sussex, : Wiley-Blackwell, 2012 | ||
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Lo trovi qui: Univ. Federico II | ||
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Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih |
Pubbl/distr/stampa | Singapore ; ; Hackensack, NJ, : World Scientific, c2013 |
Descrizione fisica | 1 online resource (415 p.) |
Disciplina | 616.3/623 |
Altri autori (Persone) | ShihChiaho |
Soggetto topico |
Chronic diseases
Hepatitis B - Pathophysiology Hepatitis C - Pathophysiology Hepatitis C - Treatment |
Soggetto genere / forma | Electronic books. |
ISBN |
1-283-85067-2
981-4299-79-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Preface; Foreword; Contents; Contributors; Hepatitis B Virus; Chapter 1 Natural Course of Chronic Hepatitis B Virus Infection Chia-Ming Chu and Yun-Fan Liaw; Introduction; Epidemiology of Chronic HBV Infection; Clinical Presentation; Phases of Chronic HBV Infection; Immune Tolerant Phase; Immune Clearance Phase; Hepatitis Activity and Acute Hepatitis Flares (HBeAg-positive Chronic Hepatitis) during Immune Clearance Phase; HBeAg to anti-HBe Seroconversion; HBeAg Persistence and Its Outcome; Inactive/Residual Phase; Spontaneous HBsAg Seroclearance; Reactivation of Hepatitis B; HBeAg Reversion
HBeAg-Negative Chronic HepatitisConcurrent Viral Superinfection as Part of Natural Course; Hepatitic C Virus; Hepatitis D Virus; Human Immunodeficiency Virus; Sequelae and Mortality; Cirrhosis and Contributing Factors; Hepatic Decompensation and Mortality; HCC and Contributing Factors; Survival of Cirrhosis; Conclusion; References; Chapter 2 Immune Response and Viral Hepatitis B David R. Milich; Introduction; Serology of Acute and Chronic HBV Infections; The PreS Envelope Antigens; Increased Complexity of the Serology of Chronic HBV Infection Human T Cell Responses in Acute and Chronic HBV InfectionCD4 + Th Cell Response; CD8 + CTL Response; Innate Immunity to HBV; Mechanisms of Liver Injury and Clearance; Transgenic Models of Immune-mediated Liver Injury; HBV Persistence; Tolerogenicity of HBc/HBeAgs; Immune Escape Variants; Manifestations of HBV-Specific T Cell Tolerance; Immunogenetics; Summary; Acknowledgment; References; Chapter 3 Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma Katherine A. McGlynn, Alison A. Evans and W. Thomas London; Introduction; History; Global Prevalence of Chronic HBV Infection Liver Cancer Incidence, Mortality, and SurvivalDemographic Factors; Age; Sex; Ethnicity; Risk Factors; Aflatoxin; Alcohol; Tobacco; Pesticides; Iron-related Conditions; Endogenous and Exogenous Hormones; Host Susceptibility; Susceptibility to Chronic HBV Infection; Susceptibility to HCC Once Chronic HBV Infection is Established; Viral Factors; Viral Load; Viral Genotype; Viral Mutations; HBV and Other Cancers; Future Directions and Unresolved Issues; References; Chapter 4 Molecular Biology of HBV-related Hepatocellular Carcinoma Amanda J. Hodgson and Betty L. Slagle; Abstract; Introduction Lessons from Other Tumor VirusesHBV and HCC; A Model for HBV-associated HCC; Immune-mediated Pathogenesis; Early Immune Response to HBV Infection; Immune-mediated Clearance of HBV; Immune Pathogenesis During Chronic Infection; Effect of HBx on Liver Regeneration; Liver Regeneration in HBV Transgenic Mice; Role of Viral Integration in HCC; General Features of HBV Integration; Lessons Learned from the WHV System; HBV Integration in Human HCCs; Potential Oncogenic Properties of HBV Gene Products; PreS1; PreS2 Truncations; Regulatory HBx Protein; HBx and the Cell Cycle Activation of Signal Transduction Pathways |
Record Nr. | UNINA-9910464764903321 |
Singapore ; ; Hackensack, NJ, : World Scientific, c2013 | ||
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Lo trovi qui: Univ. Federico II | ||
|
Chronic hepatitis B and C [[electronic resource] ] : basic science to clinical applications / / editor, Chiaho Shih |
Pubbl/distr/stampa | Singapore ; ; Hackensack, NJ, : World Scientific, c2013 |
Descrizione fisica | 1 online resource (415 p.) |
Disciplina | 616.3/623 |
Altri autori (Persone) | ShihChiaho |
Soggetto topico |
Chronic diseases
Hepatitis B - Pathophysiology Hepatitis C - Pathophysiology Hepatitis C - Treatment |
ISBN |
1-283-85067-2
981-4299-79-0 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Preface; Foreword; Contents; Contributors; Hepatitis B Virus; Chapter 1 Natural Course of Chronic Hepatitis B Virus Infection Chia-Ming Chu and Yun-Fan Liaw; Introduction; Epidemiology of Chronic HBV Infection; Clinical Presentation; Phases of Chronic HBV Infection; Immune Tolerant Phase; Immune Clearance Phase; Hepatitis Activity and Acute Hepatitis Flares (HBeAg-positive Chronic Hepatitis) during Immune Clearance Phase; HBeAg to anti-HBe Seroconversion; HBeAg Persistence and Its Outcome; Inactive/Residual Phase; Spontaneous HBsAg Seroclearance; Reactivation of Hepatitis B; HBeAg Reversion
HBeAg-Negative Chronic HepatitisConcurrent Viral Superinfection as Part of Natural Course; Hepatitic C Virus; Hepatitis D Virus; Human Immunodeficiency Virus; Sequelae and Mortality; Cirrhosis and Contributing Factors; Hepatic Decompensation and Mortality; HCC and Contributing Factors; Survival of Cirrhosis; Conclusion; References; Chapter 2 Immune Response and Viral Hepatitis B David R. Milich; Introduction; Serology of Acute and Chronic HBV Infections; The PreS Envelope Antigens; Increased Complexity of the Serology of Chronic HBV Infection Human T Cell Responses in Acute and Chronic HBV InfectionCD4 + Th Cell Response; CD8 + CTL Response; Innate Immunity to HBV; Mechanisms of Liver Injury and Clearance; Transgenic Models of Immune-mediated Liver Injury; HBV Persistence; Tolerogenicity of HBc/HBeAgs; Immune Escape Variants; Manifestations of HBV-Specific T Cell Tolerance; Immunogenetics; Summary; Acknowledgment; References; Chapter 3 Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma Katherine A. McGlynn, Alison A. Evans and W. Thomas London; Introduction; History; Global Prevalence of Chronic HBV Infection Liver Cancer Incidence, Mortality, and SurvivalDemographic Factors; Age; Sex; Ethnicity; Risk Factors; Aflatoxin; Alcohol; Tobacco; Pesticides; Iron-related Conditions; Endogenous and Exogenous Hormones; Host Susceptibility; Susceptibility to Chronic HBV Infection; Susceptibility to HCC Once Chronic HBV Infection is Established; Viral Factors; Viral Load; Viral Genotype; Viral Mutations; HBV and Other Cancers; Future Directions and Unresolved Issues; References; Chapter 4 Molecular Biology of HBV-related Hepatocellular Carcinoma Amanda J. Hodgson and Betty L. Slagle; Abstract; Introduction Lessons from Other Tumor VirusesHBV and HCC; A Model for HBV-associated HCC; Immune-mediated Pathogenesis; Early Immune Response to HBV Infection; Immune-mediated Clearance of HBV; Immune Pathogenesis During Chronic Infection; Effect of HBx on Liver Regeneration; Liver Regeneration in HBV Transgenic Mice; Role of Viral Integration in HCC; General Features of HBV Integration; Lessons Learned from the WHV System; HBV Integration in Human HCCs; Potential Oncogenic Properties of HBV Gene Products; PreS1; PreS2 Truncations; Regulatory HBx Protein; HBx and the Cell Cycle Activation of Signal Transduction Pathways |
Record Nr. | UNINA-9910789348703321 |
Singapore ; ; Hackensack, NJ, : World Scientific, c2013 | ||
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Lo trovi qui: Univ. Federico II | ||
|
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda |
Edizione | [1st ed.] |
Pubbl/distr/stampa | London, England : , : Future Medicine Ltd., , [2013] |
Descrizione fisica | 1 online resource (117 p.) |
Disciplina | 616.362306 |
Soggetto topico |
Hepatitis C - Treatment
Hepatitis C - Chemotherapy Antiviral agents |
ISBN |
1-78084-270-8
1-78084-271-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Title page; Copyright page; Contents; Foreword. Hepatitis C virus infection: from discovery to eradication; 1. Interferons in clinical trials; 2. Protease inhibitors; 3. NS5A inhibitor: daclatasvir; 4. Toll-like receptor agonists for nonresponders to hepatitis C virus treatment: hope versus promise?; 5. Treatment options in HIV-HCV-coinfected patients; 6. Treatment options for dual hepatitis C/hepatitis B virus coinfection; 7. Hepatitis C virus treatment in patients with metabolic syndrome; 8. Future directions in hepatitis C therapy; Index |
Record Nr. | UNINA-9910779873003321 |
London, England : , : Future Medicine Ltd., , [2013] | ||
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Lo trovi qui: Univ. Federico II | ||
|
Emerging therapeutic options for hepatitis C / / editors, Masao Omata, Tatsuo Kanda |
Edizione | [1st ed.] |
Pubbl/distr/stampa | London, England : , : Future Medicine Ltd., , [2013] |
Descrizione fisica | 1 online resource (117 p.) |
Disciplina | 616.362306 |
Soggetto topico |
Hepatitis C - Treatment
Hepatitis C - Chemotherapy Antiviral agents |
ISBN |
1-78084-270-8
1-78084-271-6 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Title page; Copyright page; Contents; Foreword. Hepatitis C virus infection: from discovery to eradication; 1. Interferons in clinical trials; 2. Protease inhibitors; 3. NS5A inhibitor: daclatasvir; 4. Toll-like receptor agonists for nonresponders to hepatitis C virus treatment: hope versus promise?; 5. Treatment options in HIV-HCV-coinfected patients; 6. Treatment options for dual hepatitis C/hepatitis B virus coinfection; 7. Hepatitis C virus treatment in patients with metabolic syndrome; 8. Future directions in hepatitis C therapy; Index |
Record Nr. | UNINA-9910827838803321 |
London, England : , : Future Medicine Ltd., , [2013] | ||
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Lo trovi qui: Univ. Federico II | ||
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Hepatitis C [[electronic resource] ] : an introductory guide for patients |
Pubbl/distr/stampa | [Washington, D.C.] : , : VA Hepatitis C Resource Center Program and Clinical Public Health Programs Office, Veterans Health Administration, U.S. Dept. of Veterans Affairs, , [2008] |
Descrizione fisica | 18 unnumbered pages : digital, PDF file |
Soggetto topico |
Hepatitis C - Treatment
Hepatitis, Viral - Treatment |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Hepatitis C |
Record Nr. | UNINA-9910698851403321 |
[Washington, D.C.] : , : VA Hepatitis C Resource Center Program and Clinical Public Health Programs Office, Veterans Health Administration, U.S. Dept. of Veterans Affairs, , [2008] | ||
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Lo trovi qui: Univ. Federico II | ||
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Management of hepatitis C [[electronic resource] ] : 2002 : January 1997 through April 2002 : 4,841 citations / / prepared by Kristine M. Scannell, Carolyn C. Willard, Leonard B. Seeff |
Autore | Scannell Kristine |
Pubbl/distr/stampa | Bethesda, Md. (8600 Rockville Pike) : , : U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, National Library of Medicine, Reference Section, , [2002] |
Descrizione fisica | vi, 280 pages : digital, PDF file |
Altri autori (Persone) |
WillardCarolyn
SeeffLeonard B |
Collana | Current bibliographies in medicine |
Soggetto topico |
Hepatitis C
Hepatitis C - Treatment Hepatitis C virus Hepatitis C - diagnosis Hepatitis C - drug therapy Hepatitis C - epidemiology Hepacivirus Interferon-alpha - therapeutic use |
Soggetto genere / forma |
Bibliography
Bibliographies. |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | Management of hepatitis C |
Record Nr. | UNINA-9910695711103321 |
Managing side effects of Hepatitis C treatment [[electronic resource] /] / The VA Hepatitis C Resource Center Program and the National Clinical Public Health Program, Veterans Health Administration, U.S. Department of Veterans Affairs |
Pubbl/distr/stampa | [Washington, D.C.] : , : U.S. Dept. of Veterans Affairs, , [2007] |
Descrizione fisica | 63 pages : digital, PDF file |
Soggetto topico |
Hepatitis C - Treatment
Hepatitis, Viral - Treatment |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Altri titoli varianti | HCRC VA Hepatitis C Resource Centers |
Record Nr. | UNINA-9910697843403321 |
[Washington, D.C.] : , : U.S. Dept. of Veterans Affairs, , [2007] | ||
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Lo trovi qui: Univ. Federico II | ||
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