Alcohol and cardiovascular diseases [[electronic resource]] |
Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1998 |
Descrizione fisica | 1 online resource (282 p.) |
Disciplina |
616.1
616.1071 616.861 |
Collana | Novartis Foundation symposium |
Soggetto topico |
Heart - Pathophysiology
Alcohol - Physiological effect Alcohol - Pathophysiology |
Soggetto genere / forma | Electronic books. |
ISBN |
1-282-34809-4
9786612348099 0-470-51554-6 0-470-51555-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
ALCOHOL AND CARDIOVASCULAR DISEASES; Contents; Participants; Chairman's introduction; Alcohol and cardiovascular diseases: a historical overview; Metabolic consequences of alcohol ingestion; Alcohol and the myocardium; Alcohol, free radicals and antioxidants; Alcohol, cardiac arrhythmias and sudden death; Alcohol intake, lipids and risks of myocardial infarction; Alcohol, coagulation and fibrinolysis; Alcohol, blood pressure and hypertension; General discussion; Do known cardiovascular risk factors mediate the effect of alcohol on cardiovascular disease?
The J-shaped curve and changes in drinking habitMechanisms of alcohol-related strokes; The French paradox and wine drinking; Alcohol and all-cause mortality: an overview; Alcohol, cardiovascular diseases and public health policy; Chairman's summing-up; Index of contributors; Subject index |
Record Nr. | UNINA-9910144742503321 |
Chichester ; ; New York, : J. Wiley, 1998 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Alcohol and cardiovascular diseases [[electronic resource]] |
Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1998 |
Descrizione fisica | 1 online resource (282 p.) |
Disciplina |
616.1
616.1071 616.861 |
Collana | Novartis Foundation symposium |
Soggetto topico |
Heart - Pathophysiology
Alcohol - Physiological effect Alcohol - Pathophysiology |
ISBN |
1-282-34809-4
9786612348099 0-470-51554-6 0-470-51555-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
ALCOHOL AND CARDIOVASCULAR DISEASES; Contents; Participants; Chairman's introduction; Alcohol and cardiovascular diseases: a historical overview; Metabolic consequences of alcohol ingestion; Alcohol and the myocardium; Alcohol, free radicals and antioxidants; Alcohol, cardiac arrhythmias and sudden death; Alcohol intake, lipids and risks of myocardial infarction; Alcohol, coagulation and fibrinolysis; Alcohol, blood pressure and hypertension; General discussion; Do known cardiovascular risk factors mediate the effect of alcohol on cardiovascular disease?
The J-shaped curve and changes in drinking habitMechanisms of alcohol-related strokes; The French paradox and wine drinking; Alcohol and all-cause mortality: an overview; Alcohol, cardiovascular diseases and public health policy; Chairman's summing-up; Index of contributors; Subject index |
Record Nr. | UNINA-9910830708803321 |
Chichester ; ; New York, : J. Wiley, 1998 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Alcohol and cardiovascular diseases [[electronic resource]] |
Pubbl/distr/stampa | Chichester ; ; New York, : J. Wiley, 1998 |
Descrizione fisica | 1 online resource (282 p.) |
Disciplina |
616.1
616.1071 616.861 |
Collana | Novartis Foundation symposium |
Soggetto topico |
Heart - Pathophysiology
Alcohol - Physiological effect Alcohol - Pathophysiology |
ISBN |
1-282-34809-4
9786612348099 0-470-51554-6 0-470-51555-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
ALCOHOL AND CARDIOVASCULAR DISEASES; Contents; Participants; Chairman's introduction; Alcohol and cardiovascular diseases: a historical overview; Metabolic consequences of alcohol ingestion; Alcohol and the myocardium; Alcohol, free radicals and antioxidants; Alcohol, cardiac arrhythmias and sudden death; Alcohol intake, lipids and risks of myocardial infarction; Alcohol, coagulation and fibrinolysis; Alcohol, blood pressure and hypertension; General discussion; Do known cardiovascular risk factors mediate the effect of alcohol on cardiovascular disease?
The J-shaped curve and changes in drinking habitMechanisms of alcohol-related strokes; The French paradox and wine drinking; Alcohol and all-cause mortality: an overview; Alcohol, cardiovascular diseases and public health policy; Chairman's summing-up; Index of contributors; Subject index |
Record Nr. | UNINA-9910841248103321 |
Chichester ; ; New York, : J. Wiley, 1998 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Heart physiology and pathophysiology [[electronic resource] /] / edited by Nicholas Sperelakis (editor-in-chief) ... [et. al.] |
Edizione | [4th ed.] |
Pubbl/distr/stampa | San Diego, Calif. ; ; London, : Academic Press, 2001 |
Descrizione fisica | 1 online resource (1286 p.) |
Disciplina | 612.1/7 21 |
Altri autori (Persone) | SperelakisNick <1930-> |
Soggetto topico |
Heart - Pathophysiology
Heart - Physiology |
Soggetto genere / forma | Electronic books. |
ISBN |
1-281-01892-9
9786611018924 0-08-053388-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Heart Physiology and Pathophysiology; Copyright Page; Contents; Contributors; Foreword; Preface; PART I: PUMPING ACTION AND ELECTRICAL ACTIVITY OF THE HEART; Chapter 1. Sequence of Cardiac Activation and Ventricular Mechanics; Chapter 2. Coronary Circulation and Hemodynamics; Chapter 3. Neurohumoral Control of Cardiac Function; Chapter 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure; Chapter 5. Ultrastructure of Cardiac Muscle and Blood Vessels; Chapter 6. Excitability and Impulse Propagation
Chapter 7. Electrocardiogram and Cardiac ExcitationChapter 8. Gap-Junction Channels and Healing-Over of Injury; PART II: CELLULAR ELECTROPHYSIOLOGY OF HEART AND VASCULAR SMOOTH MUSCLE; Chapter 9. Electrogenesis of the Resting Potential; Chapter 10. Cardiac Action Potentials; Chapter 11. Electrophysiology of Vascular Smooth Muscle; Chapter 12. Sodium Channels; Chapter 13. Voltage-Dependent Calcium Channels; Chapter 14. Voltage-Dependent K+ Channels; Chapter 15. Inwardly-Rectifying K+ Channels in the Heart; Chapter 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle Chapter 17. Ion Channels in Vascular Smooth MuscleChapter 18. Cardiac Pacemaker Currents; Chapter 19. Chloride Channels in Heart; Chapter 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch; PART III: PUMPS AND EXCHANGERS; Chapter 21. Cardiac Na+/K+ Pump; Chapter 22. Cardiac Na+ -Ca2+ Exchanger: Pathophysiology and Pharmacology; Chapter 23. Na+/H+ Exchanger and pH Regulation; Chapter 24. Transport in Nucleus; Chapter 25. Sarcoplasmic Reticulum Ca2+ Transport; Chapter 26. Calcium Release from Cardiac Sarcoplasmic Reticulum; PART IV: VASCULAR ENDOTHELIUM Chapter 27. Function of Vascular EndotheliumChapter 28. Ion Channels in Vascular Endothelium; PART V: EXCITATION-CONTRACTION COUPLING AND PHARMACOMECHANICAL COUPLING; Chapter 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells; Chapter 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium; Chapter 31. Vascular Smooth Muscle Contraction; PART VI: METABOLISM AND ENERGETICS; Chapter 32. Myocardial Energy Metabolism; Chapter 33. Metabolism and Energetics of Vascular Smooth Muscle; PART VII: SIGNALING SYSTEMS Chapter 34. Adrenergic Receptors in the Cardiovascular SystemChapter 35. Cardiac Action of Angiotensin II; Chapter 36. ATP and Adenosine Signal Transductions; Chapter 37. Kinase Signaling in the Cardiovascular System; Chapter 38. Calcium Signaling; Chapter 39. Diadenosine Polyphosphate Signaling in the Heart; PART VIII: DEVELOPMENTAL CHANGES AND AGING; Chapter 40. Cardiac Development and Regulation of Cardiac Transcription; Chapter 41. Developmental Changes of Ion Channels; Chapter 42. Aging of the Cardiovascular System; Chapter 43. Changes in Autonomic Responsiveness during Development PART IX: MECHANISM OF ACTION OF CARDIOACTIVE DRUGS |
Record Nr. | UNINA-9910458416503321 |
San Diego, Calif. ; ; London, : Academic Press, 2001 | ||
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Lo trovi qui: Univ. Federico II | ||
|
Heart physiology and pathophysiology [[electronic resource] /] / edited by Nicholas Sperelakis (editor-in-chief) ... [et. al.] |
Edizione | [4th ed.] |
Pubbl/distr/stampa | San Diego, Calif. ; ; London, : Academic Press, 2001 |
Descrizione fisica | 1 online resource (1286 p.) |
Disciplina | 612.1/7 21 |
Altri autori (Persone) | SperelakisNick <1930-> |
Soggetto topico |
Heart - Pathophysiology
Heart - Physiology |
ISBN |
1-281-01892-9
9786611018924 0-08-053388-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Heart Physiology and Pathophysiology; Copyright Page; Contents; Contributors; Foreword; Preface; PART I: PUMPING ACTION AND ELECTRICAL ACTIVITY OF THE HEART; Chapter 1. Sequence of Cardiac Activation and Ventricular Mechanics; Chapter 2. Coronary Circulation and Hemodynamics; Chapter 3. Neurohumoral Control of Cardiac Function; Chapter 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure; Chapter 5. Ultrastructure of Cardiac Muscle and Blood Vessels; Chapter 6. Excitability and Impulse Propagation
Chapter 7. Electrocardiogram and Cardiac ExcitationChapter 8. Gap-Junction Channels and Healing-Over of Injury; PART II: CELLULAR ELECTROPHYSIOLOGY OF HEART AND VASCULAR SMOOTH MUSCLE; Chapter 9. Electrogenesis of the Resting Potential; Chapter 10. Cardiac Action Potentials; Chapter 11. Electrophysiology of Vascular Smooth Muscle; Chapter 12. Sodium Channels; Chapter 13. Voltage-Dependent Calcium Channels; Chapter 14. Voltage-Dependent K+ Channels; Chapter 15. Inwardly-Rectifying K+ Channels in the Heart; Chapter 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle Chapter 17. Ion Channels in Vascular Smooth MuscleChapter 18. Cardiac Pacemaker Currents; Chapter 19. Chloride Channels in Heart; Chapter 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch; PART III: PUMPS AND EXCHANGERS; Chapter 21. Cardiac Na+/K+ Pump; Chapter 22. Cardiac Na+ -Ca2+ Exchanger: Pathophysiology and Pharmacology; Chapter 23. Na+/H+ Exchanger and pH Regulation; Chapter 24. Transport in Nucleus; Chapter 25. Sarcoplasmic Reticulum Ca2+ Transport; Chapter 26. Calcium Release from Cardiac Sarcoplasmic Reticulum; PART IV: VASCULAR ENDOTHELIUM Chapter 27. Function of Vascular EndotheliumChapter 28. Ion Channels in Vascular Endothelium; PART V: EXCITATION-CONTRACTION COUPLING AND PHARMACOMECHANICAL COUPLING; Chapter 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells; Chapter 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium; Chapter 31. Vascular Smooth Muscle Contraction; PART VI: METABOLISM AND ENERGETICS; Chapter 32. Myocardial Energy Metabolism; Chapter 33. Metabolism and Energetics of Vascular Smooth Muscle; PART VII: SIGNALING SYSTEMS Chapter 34. Adrenergic Receptors in the Cardiovascular SystemChapter 35. Cardiac Action of Angiotensin II; Chapter 36. ATP and Adenosine Signal Transductions; Chapter 37. Kinase Signaling in the Cardiovascular System; Chapter 38. Calcium Signaling; Chapter 39. Diadenosine Polyphosphate Signaling in the Heart; PART VIII: DEVELOPMENTAL CHANGES AND AGING; Chapter 40. Cardiac Development and Regulation of Cardiac Transcription; Chapter 41. Developmental Changes of Ion Channels; Chapter 42. Aging of the Cardiovascular System; Chapter 43. Changes in Autonomic Responsiveness during Development PART IX: MECHANISM OF ACTION OF CARDIOACTIVE DRUGS |
Record Nr. | UNINA-9910784637103321 |
San Diego, Calif. ; ; London, : Academic Press, 2001 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
Heart physiology and pathophysiology [[electronic resource] /] / edited by Nicholas Sperelakis (editor-in-chief) ... [et. al.] |
Edizione | [4th ed.] |
Pubbl/distr/stampa | San Diego, Calif. ; ; London, : Academic Press, 2001 |
Descrizione fisica | 1 online resource (1286 p.) |
Disciplina | 612.1/7 21 |
Altri autori (Persone) | SperelakisNick <1930-> |
Soggetto topico |
Heart - Pathophysiology
Heart - Physiology |
ISBN |
1-281-01892-9
9786611018924 0-08-053388-4 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Front Cover; Heart Physiology and Pathophysiology; Copyright Page; Contents; Contributors; Foreword; Preface; PART I: PUMPING ACTION AND ELECTRICAL ACTIVITY OF THE HEART; Chapter 1. Sequence of Cardiac Activation and Ventricular Mechanics; Chapter 2. Coronary Circulation and Hemodynamics; Chapter 3. Neurohumoral Control of Cardiac Function; Chapter 4. Control of Cardiac Output and its Alterations during Exercise and in Heart Failure; Chapter 5. Ultrastructure of Cardiac Muscle and Blood Vessels; Chapter 6. Excitability and Impulse Propagation
Chapter 7. Electrocardiogram and Cardiac ExcitationChapter 8. Gap-Junction Channels and Healing-Over of Injury; PART II: CELLULAR ELECTROPHYSIOLOGY OF HEART AND VASCULAR SMOOTH MUSCLE; Chapter 9. Electrogenesis of the Resting Potential; Chapter 10. Cardiac Action Potentials; Chapter 11. Electrophysiology of Vascular Smooth Muscle; Chapter 12. Sodium Channels; Chapter 13. Voltage-Dependent Calcium Channels; Chapter 14. Voltage-Dependent K+ Channels; Chapter 15. Inwardly-Rectifying K+ Channels in the Heart; Chapter 16. Voltage and Calcium-Activated K+ Channels of Coronary Smooth Muscle Chapter 17. Ion Channels in Vascular Smooth MuscleChapter 18. Cardiac Pacemaker Currents; Chapter 19. Chloride Channels in Heart; Chapter 20. Regulation of Cardiac Ion Channels by Phosphorylation, Ca2+, Cytoskeleton, and Stretch; PART III: PUMPS AND EXCHANGERS; Chapter 21. Cardiac Na+/K+ Pump; Chapter 22. Cardiac Na+ -Ca2+ Exchanger: Pathophysiology and Pharmacology; Chapter 23. Na+/H+ Exchanger and pH Regulation; Chapter 24. Transport in Nucleus; Chapter 25. Sarcoplasmic Reticulum Ca2+ Transport; Chapter 26. Calcium Release from Cardiac Sarcoplasmic Reticulum; PART IV: VASCULAR ENDOTHELIUM Chapter 27. Function of Vascular EndotheliumChapter 28. Ion Channels in Vascular Endothelium; PART V: EXCITATION-CONTRACTION COUPLING AND PHARMACOMECHANICAL COUPLING; Chapter 29. Electromechanical and Pharmacomechanical Coupling in Vascular Smooth Muscle Cells; Chapter 30. Mechanisms Regulating Cardiac Myofilament Response to Calcium; Chapter 31. Vascular Smooth Muscle Contraction; PART VI: METABOLISM AND ENERGETICS; Chapter 32. Myocardial Energy Metabolism; Chapter 33. Metabolism and Energetics of Vascular Smooth Muscle; PART VII: SIGNALING SYSTEMS Chapter 34. Adrenergic Receptors in the Cardiovascular SystemChapter 35. Cardiac Action of Angiotensin II; Chapter 36. ATP and Adenosine Signal Transductions; Chapter 37. Kinase Signaling in the Cardiovascular System; Chapter 38. Calcium Signaling; Chapter 39. Diadenosine Polyphosphate Signaling in the Heart; PART VIII: DEVELOPMENTAL CHANGES AND AGING; Chapter 40. Cardiac Development and Regulation of Cardiac Transcription; Chapter 41. Developmental Changes of Ion Channels; Chapter 42. Aging of the Cardiovascular System; Chapter 43. Changes in Autonomic Responsiveness during Development PART IX: MECHANISM OF ACTION OF CARDIOACTIVE DRUGS |
Record Nr. | UNINA-9910821567003321 |
San Diego, Calif. ; ; London, : Academic Press, 2001 | ||
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Lo trovi qui: Univ. Federico II | ||
|
The Heart's Vortex [[electronic resource] ] : intracardiac blood flow phenomena / / Ares Pasipoularides |
Pubbl/distr/stampa | Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 |
Descrizione fisica | 1 online resource (954 p.) |
Disciplina | 616.1 |
Altri autori (Persone) | PasipoularidesA |
Soggetto topico |
Hemodynamics
Heart - Physiology Heart - Pathophysiology |
Soggetto genere / forma | Electronic books. |
ISBN | 1-60795-116-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Front matter ""; ""Table of Contents""; ""Part I : Fundamentals of Intracardiac Flows and Their Measurement""; ""1: Introduction""; ""2: Handy Mathematical Instruments of Thought""; ""3: Some Notable Pioneers""; ""4: Fluid Dynamics of Unsteady Flow""; ""5: Micromanometric, Velocimetric, Angio- and Echocardiographic Measurements""; ""6: Cardiac Morphology and Flow Patterns: Structural-Functional Correlations""; ""7: Cardiac Cycle and Central Pressure, Flow, and Volume Pulses""; ""8: Addendum to Chapters 4, 5, & 7: A Gallery of Multisensor Catheter Cardiodynamics""
""9: Vortex Formation in Fluid Flow""""Part II: Visualization of Intracardiac Blood Flows: Methodologies, Frameworks, and Insights ""; ""10: Cardiac Computed Tomography, Magnetic Resonance, and Real-Time 3-D Echocardiography""; ""11: Postprocessing Exploration Techniques and Display of Tomographic Data""; ""12: Computational Fluid Dynamics, or ""CFD""""; ""13: CFD of Ventricular Ejection""; ""14: CFD of Ventricular Filling: Heart's Vortex""; ""15: Fluid Dynamic Epigenetic Factors in Cardiogenesis and Remodeling"" ""16: A Recapitulation with Clinical and Basic Science Perspectives: Directions of Future Research""""17: Epilogue""; ""Part III: Appendix""; ""Index "" |
Record Nr. | UNINA-9910458520803321 |
Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 | ||
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Lo trovi qui: Univ. Federico II | ||
|
The Heart's Vortex [[electronic resource] ] : intracardiac blood flow phenomena / / Ares Pasipoularides |
Pubbl/distr/stampa | Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 |
Descrizione fisica | 1 online resource (954 p.) |
Disciplina | 616.1 |
Altri autori (Persone) | PasipoularidesA |
Soggetto topico |
Hemodynamics
Heart - Physiology Heart - Pathophysiology |
ISBN | 1-60795-116-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Front matter ""; ""Table of Contents""; ""Part I : Fundamentals of Intracardiac Flows and Their Measurement""; ""1: Introduction""; ""2: Handy Mathematical Instruments of Thought""; ""3: Some Notable Pioneers""; ""4: Fluid Dynamics of Unsteady Flow""; ""5: Micromanometric, Velocimetric, Angio- and Echocardiographic Measurements""; ""6: Cardiac Morphology and Flow Patterns: Structural-Functional Correlations""; ""7: Cardiac Cycle and Central Pressure, Flow, and Volume Pulses""; ""8: Addendum to Chapters 4, 5, & 7: A Gallery of Multisensor Catheter Cardiodynamics""
""9: Vortex Formation in Fluid Flow""""Part II: Visualization of Intracardiac Blood Flows: Methodologies, Frameworks, and Insights ""; ""10: Cardiac Computed Tomography, Magnetic Resonance, and Real-Time 3-D Echocardiography""; ""11: Postprocessing Exploration Techniques and Display of Tomographic Data""; ""12: Computational Fluid Dynamics, or ""CFD""""; ""13: CFD of Ventricular Ejection""; ""14: CFD of Ventricular Filling: Heart's Vortex""; ""15: Fluid Dynamic Epigenetic Factors in Cardiogenesis and Remodeling"" ""16: A Recapitulation with Clinical and Basic Science Perspectives: Directions of Future Research""""17: Epilogue""; ""Part III: Appendix""; ""Index "" |
Record Nr. | UNINA-9910791532603321 |
Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 | ||
![]() | ||
Lo trovi qui: Univ. Federico II | ||
|
The Heart's Vortex [[electronic resource] ] : intracardiac blood flow phenomena / / Ares Pasipoularides |
Pubbl/distr/stampa | Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 |
Descrizione fisica | 1 online resource (954 p.) |
Disciplina | 616.1 |
Altri autori (Persone) | PasipoularidesA |
Soggetto topico |
Hemodynamics
Heart - Physiology Heart - Pathophysiology |
ISBN | 1-60795-116-9 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
""Front matter ""; ""Table of Contents""; ""Part I : Fundamentals of Intracardiac Flows and Their Measurement""; ""1: Introduction""; ""2: Handy Mathematical Instruments of Thought""; ""3: Some Notable Pioneers""; ""4: Fluid Dynamics of Unsteady Flow""; ""5: Micromanometric, Velocimetric, Angio- and Echocardiographic Measurements""; ""6: Cardiac Morphology and Flow Patterns: Structural-Functional Correlations""; ""7: Cardiac Cycle and Central Pressure, Flow, and Volume Pulses""; ""8: Addendum to Chapters 4, 5, & 7: A Gallery of Multisensor Catheter Cardiodynamics""
""9: Vortex Formation in Fluid Flow""""Part II: Visualization of Intracardiac Blood Flows: Methodologies, Frameworks, and Insights ""; ""10: Cardiac Computed Tomography, Magnetic Resonance, and Real-Time 3-D Echocardiography""; ""11: Postprocessing Exploration Techniques and Display of Tomographic Data""; ""12: Computational Fluid Dynamics, or ""CFD""""; ""13: CFD of Ventricular Ejection""; ""14: CFD of Ventricular Filling: Heart's Vortex""; ""15: Fluid Dynamic Epigenetic Factors in Cardiogenesis and Remodeling"" ""16: A Recapitulation with Clinical and Basic Science Perspectives: Directions of Future Research""""17: Epilogue""; ""Part III: Appendix""; ""Index "" |
Record Nr. | UNINA-9910814236903321 |
Shelton, CT., : People's Medical Publishing House USA Ltd, c2010 | ||
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Lo trovi qui: Univ. Federico II | ||
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The hERG cardial potassium channel [[electronic resource] ] : structure, function, and long QT syndrome / / [editors, Derek J. Chadwick, James Goode] |
Pubbl/distr/stampa | New York, : J. Wiley, 2005 |
Descrizione fisica | 1 online resource (309 p.) |
Disciplina |
612.1/7
612.173 616.1207 |
Altri autori (Persone) |
ChadwickDerek
GoodeJamie |
Collana | Novartis Foundation symposium |
Soggetto topico |
Potassium channels
Long QT syndrome Heart - Physiology Heart - Pathophysiology |
Soggetto genere / forma | Electronic books. |
ISBN |
1-280-27526-X
9786610275267 0-470-02142-X 0-470-02141-1 |
Formato | Materiale a stampa ![]() |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
THE hERG CARDIAC POTASSIUM CHANNEL: STRUCTURE, FUNCTION AND LONG QT SYNDROME; Contents; Participants; Chair's introduction; Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart; Discussion; Structure-function studies of the outer mouth and voltage sensor domain of hERG; Discussion; General discussion I; Voltage sensor movement in the hERGK(+) channel; Discussion; hERG channel trafficking; Discussion; Dynamic control of hERG/I(Kr) by PKA-mediated interactions with 14-3-3; Discussion; General discussion II
Does hERG coassemble with a b subunit? Evidence for roles of MinK and MiRP1Discussion; hERG block, QT liability and sudden cardiac death; Discussion; Structural determinants for high-affinity block of hERG potassium channels; Discussion; Physicochemical basis for binding and voltage-dependent block of hERG channels by structurally diverse drugs; Discussion; In silico modelling-pharmacophores and hERG channel models; Discussion; The long QTsyndrome: a clinical counterpart of HERG mutations; Discussion; Cellular mechanisms of Torsade de Pointes; Discussion Expression and role of hERG channels in cancer cellsDiscussion; TRIad: foundation for proarrhythmia (triangulation, reverse use dependence and instability); Discussion; Drug-induced QT interval prolongation: regulatory guidance and perspectives on hERG channel studies; Discussion; Closing remarks; Index of contributors; Subject index |
Record Nr. | UNINA-9910143740603321 |
New York, : J. Wiley, 2005 | ||
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Lo trovi qui: Univ. Federico II | ||
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