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Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias
| Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias |
| Autore | Brito Arias Marco Augusto |
| Pubbl/distr/stampa | Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] |
| Descrizione fisica | 1 online resource (334 pages) |
| Disciplina | 572.567 |
| Soggetto topico |
Glycolysis
Amino acids Enzymes - Synthesis |
| Soggetto genere / forma | Electronic books. |
| ISBN | 981-14-6090-6 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910494645403321 |
Brito Arias Marco Augusto
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| Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias
| Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias |
| Autore | Brito Arias Marco Augusto |
| Pubbl/distr/stampa | Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] |
| Descrizione fisica | 1 online resource (334 pages) |
| Disciplina | 572.567 |
| Soggetto topico |
Glycolysis
Amino acids Enzymes - Synthesis |
| ISBN | 981-14-6090-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910794337203321 |
|
Brito Arias Marco Augusto
|
||
| Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias
| Enzymes involved in glycolysis, fatty acid and amino acid biosynthesis : active site mechanisms and inhibition / / authored by Marco Brito-Arias |
| Autore | Brito Arias Marco Augusto |
| Pubbl/distr/stampa | Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] |
| Descrizione fisica | 1 online resource (334 pages) |
| Disciplina | 572.567 |
| Soggetto topico |
Glycolysis
Amino acids Enzymes - Synthesis |
| ISBN | 981-14-6090-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910807164303321 |
|
Brito Arias Marco Augusto
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| Singapore : , : Bentham Science Publishers Pte Ltd., , [2020] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
GAPDH : biological properties and diversity / / Norbert W. Seidler
| GAPDH : biological properties and diversity / / Norbert W. Seidler |
| Autore | Seidler Norbert W |
| Edizione | [1st ed. 2013.] |
| Pubbl/distr/stampa | Dordrecht ; ; New York, : Springer, 2012, c2013 |
| Descrizione fisica | 1 online resource (303 p.) |
| Disciplina |
616.97
616.97/5 616.975 |
| Collana | Advances in experimental medicine and biology |
| Soggetto topico |
Enzymes - Synthesis
Enzymology Glycolysis |
| ISBN |
9789400747166
9400747160 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
GAPDH: Biological Propertiesand Diversity; Contents; Introduction; Chapter 1: Basic Biology of GAPDH; 1.1 The GAPDH Gene; 1.1.1 Coding Region; 1.1.2 Promoter Sequence; 1.1.2.1 Hypoxia-Responsive Elements; 1.1.2.2 Basal Level Expression; 1.1.2.3 Glutamine-Responsive Elements; 1.1.3 Testes-Specific Isoform; 1.1.4 GAPDH Pseudogenes; 1.2 Regulation of GAPDH Expression; 1.2.1 Tissue Specificity; 1.2.2 Tracking GAPDH Information Electronically; 1.2.3 Cancer; 1.3 Cellular Levels of GAPDH; 1.4 Oxidoreductase Activity of GAPDH; 1.4.1 Mechanism of Catalysis; 1.4.2 Kinetic Parameters
1.5 Architecture of the GAPDH Protein1.5.1 Asymmetric Homotetramer; 1.5.2 Dinucleotide Binding Domain; 1.5.3 Catalytic Domain; References; Chapter 2: GAPDH and Intermediary Metabolism; 2.1 GAPDH, the Glycolytic Lynch-Pin; 2.1.1 Metabolic Switch; 2.1.2 Glycolytic Tissues; 2.1.3 Anaerobic Glycolysis; 2.2 Determining GAPDH Activity; 2.2.1 Chemical Inhibitors; 2.2.2 Measurement of Glycolytic Flux; 2.2.3 Oxidoreductase Activity of GAPDH; 2.2.3.1 Conditions of Assay; Buffer Selection; Triethanolamine Buffer; Sodium Phosphate Buffer; GAPDH (rabbit muscle); Reagents; NAD+ stock solution (10mM) d/l-glyceraldehyde stock solution (200mM)2.2.3.2 Assay Protocol; Determine Rate of NAD+ Reduction; Calculate Specific Activity; 2.3 Role of GAPDH Metabolites; 2.3.1 Counter-Catalytic Activity; 2.3.2 Controlling NADH Levels; 2.3.3 Phosphocreatine, as a Competitive Inhibitor; 2.3.4 Metabolic Parameters in the Brain; 2.4 Comparative Analysis; 2.4.1 Structure-Function of NAD+-Binding; 2.4.2 Sequence Homology; References; Chapter 3: Compartmentation of GAPDH; 3.1 Compartmentation of Glycolytic Energy; 3.1.1 Microzones of Cellular ATP; 3.1.2 Focal Regulation of NAD+/NADH Ratios 3.1.3 Channeling of Metabolites3.1.4 Non-glycolytic Compartmentation; 3.2 Binding to the Plasma Membrane; 3.2.1 SLC4 Anion Exchanger; 3.2.1.1 Band 3 in Erythrocytes; 3.2.1.2 Kidney AE1 Isoform; 3.2.2 Na+/K+-ATPase; 3.2.3 ATP-Sensitive K+-Channel; 3.2.4 GLUT Transporters; 3.2.4.1 GLUT1 Transporter in Erythrocytes; 3.2.4.2 GLUT4 Transporter; 3.2.5 GABA (Type A) Receptor; 3.2.6 GAPDH, as a Lactoferrin Receptor; 3.3 Translocation to the Nucleus; 3.4 Other Non-cytosolic Destinations; 3.4.1 Clathrin-Coated Vesicles; 3.4.2 Golgi Apparatus and Endoplasmic Reticulum; 3.4.3 Sarcoplasmic Reticulum 3.4.4 Mitochondria3.5 Dendrites, Axons and Synapses; 3.5.1 Synaptic Vesicles; 3.5.2 Post-synaptic Density; 3.6 Specialized Compartment for Spermatogenic GAPDH; References; Chapter 4: Functional Diversity; 4.1 Classical Example of Protein `Moonlighting ́; 4.1.1 Evolutionary Considerations; 4.1.2 Molecular Mechanisms; 4.2 Structural Organization of the Cell; 4.2.1 Cytoskeletal Components; 4.2.1.1 Actin Filaments; 4.2.1.2 Microtubules; 4.2.2 Organelle Biogenesis; 4.2.2.1 Triadic Junction; 4.2.2.2 Nuclear Envelope; 4.2.2.3 Vesicle Recycling/Membrane Fusion; 4.2.2.4 Cell Polarization 4.2.2.5 Golgi and Endoplasmic Reticulum |
| Record Nr. | UNINA-9910437616403321 |
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Seidler Norbert W
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| Dordrecht ; ; New York, : Springer, 2012, c2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) : the quintessential moonlighting protein in normal cell function and in human disease / / Michael A. Sirover
| Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) : the quintessential moonlighting protein in normal cell function and in human disease / / Michael A. Sirover |
| Autore | Sirover Michael |
| Pubbl/distr/stampa | London, England : , : Academic Press, , 2017 |
| Descrizione fisica | 1 online resource (307 pages) : illustrations (some color), tables |
| Disciplina | 597.0333 |
| Soggetto topico |
Glycolysis
Aldehyde dehydrogenase |
| ISBN | 0-12-809898-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Section I. The Role of Moonlighting GAPDH in Normal Cell Function. The role of moonlighting GAPDH in cell proliferation : the dynamic nature of GAPDH expression and subcellular localization -- Moonlighting GAPDH and the transcriptional regulation of gene expression : multiprotein complex formation and mechanisms of nuclear translocation -- The diversity of moonlighting GAPDH function in posttranscriptional RNA regulation : mRNA stability, tRNA processing, and viral pathogenesis -- The role of moonlighting GAPDH in membrane structure and function : membrane fusion and iron metabolism -- The role of moonlighting GAPDH in intracellular membrane trafficking : tubulin regulation and modulation of cytoskeletal structure -- Moonlighting GAPDH and the maintenance of DNA integrity : preservation of genetic information and cancer facilitation -- Moonlighting GAPDH in neuronal structure and function : regulation of ion channels and signal transduction -- Section II. Physiological Stress and GAPDH Functional Diversity. The significance of nitric oxide-modified GAPDH : regulation of apoptosis, cell signaling, and heme metabolism -- GAPDH and hypoxia : mechanisms of cell survival during oxygen deprivation -- Moonlighting GAPDH and ischemia : cellular and molecular effects of oxygen deprivation and reperfusion -- Section II. The Pathology of GAPDH Functional Diversity. GAPDH and tumorigenesis : molecular mechanisms of cancer development and survival -- Moonlighting GAPDH and age-related neurodegenerative disease : diversity of protein interactions and complexity of function -- Functional diversity of GAPDH in infection and immunity : the complexity of "simple" organisms -- Moonlighting GAPDH and diabetes : pleiotropic effects of perturbations in GAPDH structure and function -- Section IV. The Pharmacology of Moonlighting GAPDH -- Section V. The Unique Role of Sperm-Specific GAPDH -- Section VI. Discussion. |
| Record Nr. | UNINA-9910583006603321 |
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Sirover Michael
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| London, England : , : Academic Press, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Glycolysis [[electronic resource] ] : regulation, processes and diseases / / Paul N. Lithaw, editor
| Glycolysis [[electronic resource] ] : regulation, processes and diseases / / Paul N. Lithaw, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (210 p.) |
| Disciplina | 572/.567 |
| Altri autori (Persone) | LithawPaul N |
| Collana | Biochemistry research trends series |
| Soggetto topico | Glycolysis |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-61668-632-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Regulation of glycolysis in lactococcus lactis / Maria Papagianni -- The cancer-hypoxia/decreased respiration-glycolysis connection : new insights from Nobel Prize-winner, Otto Warburg, MD / Brian Scott Peskin -- Pattern formation and dissipation in a model glycolytic system : the effect of complexing reaction with the activator / Arun K. Dutt -- The role of skeletal muscle glycolysis in whole body metabolic regulation and type 2 diabetes / Jørgen Jensen -- Glycolysis and the lung / G.S. Maritz -- Transcriptional and post-transcriptional regulation of glycolysis in microbial cells / Dave Siak-Wei Ow ... [et al.] -- Blood lactate concentrations, resistive force selection, and high intensity cycle ergometry. Is intense running ability related? / Julien Steven Baker and Bruce Davies -- Blood lactate concentrations following repeat brief maximal intermittent exercise in man. Glycolytic energy supply and influence of plasma volume changes / Julien S. Baker ... [et al.] -- Mathematical modeling as a tool for decoding the control of metabolic pathways / Eberhard Voit -- Influencing metabolism during critical illness : potential novel strategies / N.P. Juffermans ... [et al.] -- The anti-aging effect of enhanced glycolysis : another role of the Warburg effect / Hiroshi Kondoh, Takeshi Maruyama. |
| Record Nr. | UNINA-9910456491003321 |
| Hauppauge, N.Y., : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Glycolysis [[electronic resource] ] : regulation, processes and diseases / / Paul N. Lithaw, editor
| Glycolysis [[electronic resource] ] : regulation, processes and diseases / / Paul N. Lithaw, editor |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (210 p.) |
| Disciplina | 572/.567 |
| Altri autori (Persone) | LithawPaul N |
| Collana | Biochemistry research trends series |
| Soggetto topico | Glycolysis |
| ISBN | 1-61668-632-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Regulation of glycolysis in lactococcus lactis / Maria Papagianni -- The cancer-hypoxia/decreased respiration-glycolysis connection : new insights from Nobel Prize-winner, Otto Warburg, MD / Brian Scott Peskin -- Pattern formation and dissipation in a model glycolytic system : the effect of complexing reaction with the activator / Arun K. Dutt -- The role of skeletal muscle glycolysis in whole body metabolic regulation and type 2 diabetes / Jørgen Jensen -- Glycolysis and the lung / G.S. Maritz -- Transcriptional and post-transcriptional regulation of glycolysis in microbial cells / Dave Siak-Wei Ow ... [et al.] -- Blood lactate concentrations, resistive force selection, and high intensity cycle ergometry. Is intense running ability related? / Julien Steven Baker and Bruce Davies -- Blood lactate concentrations following repeat brief maximal intermittent exercise in man. Glycolytic energy supply and influence of plasma volume changes / Julien S. Baker ... [et al.] -- Mathematical modeling as a tool for decoding the control of metabolic pathways / Eberhard Voit -- Influencing metabolism during critical illness : potential novel strategies / N.P. Juffermans ... [et al.] -- The anti-aging effect of enhanced glycolysis : another role of the Warburg effect / Hiroshi Kondoh, Takeshi Maruyama. |
| Record Nr. | UNINA-9910781173303321 |
| Hauppauge, N.Y., : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Glycolysis : regulation, processes and diseases / / Paul N. Lithaw, editor
| Glycolysis : regulation, processes and diseases / / Paul N. Lithaw, editor |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hauppauge, N.Y., : Nova Science Publishers, c2009 |
| Descrizione fisica | 1 online resource (210 p.) |
| Disciplina | 572/.567 |
| Altri autori (Persone) | LithawPaul N |
| Collana | Biochemistry research trends series |
| Soggetto topico | Glycolysis |
| ISBN | 1-61668-632-4 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Regulation of glycolysis in lactococcus lactis / Maria Papagianni -- The cancer-hypoxia/decreased respiration-glycolysis connection : new insights from Nobel Prize-winner, Otto Warburg, MD / Brian Scott Peskin -- Pattern formation and dissipation in a model glycolytic system : the effect of complexing reaction with the activator / Arun K. Dutt -- The role of skeletal muscle glycolysis in whole body metabolic regulation and type 2 diabetes / Jørgen Jensen -- Glycolysis and the lung / G.S. Maritz -- Transcriptional and post-transcriptional regulation of glycolysis in microbial cells / Dave Siak-Wei Ow ... [et al.] -- Blood lactate concentrations, resistive force selection, and high intensity cycle ergometry. Is intense running ability related? / Julien Steven Baker and Bruce Davies -- Blood lactate concentrations following repeat brief maximal intermittent exercise in man. Glycolytic energy supply and influence of plasma volume changes / Julien S. Baker ... [et al.] -- Mathematical modeling as a tool for decoding the control of metabolic pathways / Eberhard Voit -- Influencing metabolism during critical illness : potential novel strategies / N.P. Juffermans ... [et al.] -- The anti-aging effect of enhanced glycolysis : another role of the Warburg effect / Hiroshi Kondoh, Takeshi Maruyama. |
| Record Nr. | UNINA-9910959316603321 |
| Hauppauge, N.Y., : Nova Science Publishers, c2009 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Glycolysis
(8)
- Enzymes - Synthesis (4)
- Amino acids (3)
- Aldehyde dehydrogenase (1)
- Enzymology (1)