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The clinibook [[electronic resource] ] : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer
| The clinibook [[electronic resource] ] : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer |
| Autore | Cohen-Haguenauer Odile |
| Pubbl/distr/stampa | Paris, : EDP Sciences, 2012 |
| Descrizione fisica | 1 online resource (589 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) | Cohen-HaguenauerOdile |
| Soggetto topico | Genetic transformation |
| ISBN |
1-299-27682-2
2-84254-237-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Technologies and pre-clinical studies -- pt. 2. Clinical trials and regulatory issues. |
| Record Nr. | UNINA-9910792058803321 |
Cohen-Haguenauer Odile
|
||
| Paris, : EDP Sciences, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The clinibook : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer
| The clinibook : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer |
| Autore | Cohen-Haguenauer Odile |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Paris, : EDP Sciences, 2012 |
| Descrizione fisica | 1 online resource (589 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) | Cohen-HaguenauerOdile |
| Soggetto topico | Genetic transformation |
| ISBN |
1-299-27682-2
2-84254-237-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Technologies and pre-clinical studies -- pt. 2. Clinical trials and regulatory issues. |
| Record Nr. | UNINA-9910826134503321 |
|
Cohen-Haguenauer Odile
|
||
| Paris, : EDP Sciences, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The clinibook [[electronic resource] ] : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer
| The clinibook [[electronic resource] ] : clinical gene transfer : state of the art / / edited by Odile Cohen-Haguenauer |
| Pubbl/distr/stampa | Paris, : EDP Sciences, 2012 |
| Descrizione fisica | 1 online resource (589 p.) |
| Disciplina | 571.96 |
| Altri autori (Persone) | Cohen-HaguenauerOdile |
| Soggetto topico | Genetic transformation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-299-27682-2
2-84254-237-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | pt. 1. Technologies and pre-clinical studies -- pt. 2. Clinical trials and regulatory issues. |
| Record Nr. | UNINA-9910465391303321 |
| Paris, : EDP Sciences, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910144734503321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910830019203321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910841774903321 |
|
Doerfler Walter <1933->
|
||
| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Genetic transformation / / edited by María Alejandra Alvarez
| Genetic transformation / / edited by María Alejandra Alvarez |
| Pubbl/distr/stampa | IntechOpen, 2011 |
| Descrizione fisica | 1 online resource (342 pages) : illustrations |
| Disciplina | 574.873282 |
| Soggetto topico | Genetic transformation |
| Soggetto non controllato |
Life Sciences
Human Genetics Molecular Genetics Genetics and Molecular Biology Biochemistry |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910138401103321 |
| IntechOpen, 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The journal of gene medicine
| The journal of gene medicine |
| Pubbl/distr/stampa | New York, NY, : John Wiley & Sons, ©1999- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616 |
| Soggetto topico |
Genetic transformation
Gene therapy Cellular therapy Gene Transfer Techniques Genetic Therapy Thérapie génique Thérapie cellulaire |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| Soggetto non controllato | Genetics |
| ISSN | 1521-2254 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Gene medicine |
| Record Nr. | UNINA-9910144710403321 |
| New York, NY, : John Wiley & Sons, ©1999- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The journal of gene medicine
| The journal of gene medicine |
| Pubbl/distr/stampa | New York, NY, : John Wiley & Sons, ©1999- |
| Descrizione fisica | 1 online resource |
| Disciplina | 616 |
| Soggetto topico |
Genetic transformation
Gene therapy Cellular therapy Gene Transfer Techniques Genetic Therapy Thérapie génique Thérapie cellulaire |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| Soggetto non controllato | Genetics |
| ISSN | 1521-2254 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Gene medicine |
| Record Nr. | UNISA-996203952203316 |
| New York, NY, : John Wiley & Sons, ©1999- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The major transitions in evolution [[electronic resource] /] / John Maynard Smith and Eörs Szathmáry
| The major transitions in evolution [[electronic resource] /] / John Maynard Smith and Eörs Szathmáry |
| Autore | Maynard Smith John <1920-2004.> |
| Pubbl/distr/stampa | Oxford ; ; New York, : Oxford University Press, 1997 |
| Descrizione fisica | 1 online resource (361 p.) |
| Disciplina | 576.8 |
| Altri autori (Persone) | SzathmáryEörs |
| Collana | Oxford scholarship online |
| Soggetto topico |
Evolution (Biology)
Genetic transformation Natural selection |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-19-191923-3
0-19-158600-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Contents; List of tables; Preface; 1 Introduction; 2 What is life?; 3 Chemical evolution; 4 The evolution of templates; 5 The chicken and egg problem; 6 The origin of translation and the genetic code; 7 The origin of protocells; 8 The origin of eukaryotes; 9 The origin of sex and the nature of species; 10 Intragenomic conflict; 11 Symbiosis; 12 Development in simple organisms; 13 Gene regulation and cell heredity; 14 The development of spatial patterns; 15 Development and evolution; 16 The origins of societies; 17 The origin of language; References; Author index; Subject index |
| Record Nr. | UNINA-9910465508203321 |
|
Maynard Smith John <1920-2004.>
|
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| Oxford ; ; New York, : Oxford University Press, 1997 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Genetic transformation
(25)
- Evolution (Biology) (9)
- Adenoviruses (3)
- Biodiversity (3)
- DNA (3)