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Free radical biology & medicine
| Free radical biology & medicine |
| Pubbl/distr/stampa | [New York, NY], : Elsevier Science |
| Soggetto topico |
Free radicals (Chemistry)
Free radicals (Chemistry) - Physiological effect Free radicals (Chemistry) - Toxicology Biology Free Radicals Medicine Radicaux libres (Chimie) Radicaux libres (Chimie) - Effets physiologiques Radicaux libres (Chimie) - Toxicologie Biologie biology |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| Soggetto non controllato |
Titles of electronic journals
ScienceDirect - Text files |
| ISSN | 1873-4596 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Free radical biology and medicine |
| Record Nr. | UNISA-996203104903316 |
| [New York, NY], : Elsevier Science | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Free radical biology & medicine
| Free radical biology & medicine |
| Pubbl/distr/stampa | [New York, NY], : Elsevier Science |
| Soggetto topico |
Free radicals (Chemistry)
Free radicals (Chemistry) - Physiological effect Free radicals (Chemistry) - Toxicology Biology Free Radicals Medicine Radicaux libres (Chimie) Radicaux libres (Chimie) - Effets physiologiques Radicaux libres (Chimie) - Toxicologie Biologie biology |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| ISSN | 1873-4596 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Free radical biology and medicine |
| Record Nr. | UNINA-9910145869003321 |
| [New York, NY], : Elsevier Science | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free radical biomedicine [[electronic resource] ] : principles, clinical correlations, and methodologies / / author, Y. Robert Li
| Free radical biomedicine [[electronic resource] ] : principles, clinical correlations, and methodologies / / author, Y. Robert Li |
| Autore | Li Y. Robert |
| Pubbl/distr/stampa | [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (350 p.) |
| Disciplina | 541.224 |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Pathology, Molecular |
| Soggetto genere / forma | Electronic books. |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover page; 03 REVISED eBooks End User License Agreement-Website; 04 Table of Contents; 05 About the Book; 06 About the Author-corrected; 08 Preface; 10 Part I; 11 Chapter 1-corrected; 12 Chapter 2-corrected; 13 Chapter 3-corrected; 14 Part II; 15 Chapter 4-corrected; 16 Chapter 5-corrected; 17 Chapter 6-corrected; 18 Chapter 7-corrected; 19 Chapter 8-corrected; 20 Chapter 9-corrected; 21 Chapter 10-corrected; 22 Chapter 11-corrected; 23 Chapter 12-corrected; 24 Part III; 25 Chapter 13-corrected; 26 Chapter 14-corrected; 27 Chapter 15-corrected; 28 Index-corrected |
| Record Nr. | UNINA-9910452405703321 |
Li Y. Robert
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| [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free radical biomedicine [[electronic resource] ] : principles, clinical correlations, and methodologies / / author, Y. Robert Li
| Free radical biomedicine [[electronic resource] ] : principles, clinical correlations, and methodologies / / author, Y. Robert Li |
| Autore | Li Y. Robert |
| Pubbl/distr/stampa | [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (350 p.) |
| Disciplina | 541.224 |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Pathology, Molecular |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover page; 03 REVISED eBooks End User License Agreement-Website; 04 Table of Contents; 05 About the Book; 06 About the Author-corrected; 08 Preface; 10 Part I; 11 Chapter 1-corrected; 12 Chapter 2-corrected; 13 Chapter 3-corrected; 14 Part II; 15 Chapter 4-corrected; 16 Chapter 5-corrected; 17 Chapter 6-corrected; 18 Chapter 7-corrected; 19 Chapter 8-corrected; 20 Chapter 9-corrected; 21 Chapter 10-corrected; 22 Chapter 11-corrected; 23 Chapter 12-corrected; 24 Part III; 25 Chapter 13-corrected; 26 Chapter 14-corrected; 27 Chapter 15-corrected; 28 Index-corrected |
| Record Nr. | UNINA-9910779202603321 |
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Li Y. Robert
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| [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free radical biomedicine : principles, clinical correlations, and methodologies / / author, Y. Robert Li
| Free radical biomedicine : principles, clinical correlations, and methodologies / / author, Y. Robert Li |
| Autore | Li Y. Robert |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] |
| Descrizione fisica | 1 online resource (350 p.) |
| Disciplina | 541.224 |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Pathology, Molecular |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover page; 03 REVISED eBooks End User License Agreement-Website; 04 Table of Contents; 05 About the Book; 06 About the Author-corrected; 08 Preface; 10 Part I; 11 Chapter 1-corrected; 12 Chapter 2-corrected; 13 Chapter 3-corrected; 14 Part II; 15 Chapter 4-corrected; 16 Chapter 5-corrected; 17 Chapter 6-corrected; 18 Chapter 7-corrected; 19 Chapter 8-corrected; 20 Chapter 9-corrected; 21 Chapter 10-corrected; 22 Chapter 11-corrected; 23 Chapter 12-corrected; 24 Part III; 25 Chapter 13-corrected; 26 Chapter 14-corrected; 27 Chapter 15-corrected; 28 Index-corrected |
| Record Nr. | UNINA-9910961365103321 |
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Li Y. Robert
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| [Saif Zone, Sharjah, U.A.E], : Bentham Books, [2012] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free Radical Medicine and Biology / / Kusal K. Das, editor
| Free Radical Medicine and Biology / / Kusal K. Das, editor |
| Pubbl/distr/stampa | London : , : IntechOpen, , 2020 |
| Descrizione fisica | 1 online resource (130 pages) |
| Disciplina | 616.07 |
| Soggetto topico | Free radicals (Chemistry) - Physiological effect |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688439303321 |
| London : , : IntechOpen, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Free radicals in biology and medicine / Barry Halliwell, John M. C. Gutteridge
| Free radicals in biology and medicine / Barry Halliwell, John M. C. Gutteridge |
| Autore | Halliwell, Barry |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | Oxford : Clarendon Press, 1989 |
| Descrizione fisica | xvi, 543 p. : ill. ; 24 cm |
| Disciplina | 612.015 |
| Altri autori (Persone) | Gutteridge, John M. C. |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Superoxide - Physiological effect Pathology, Molecular Biology Free Radicals Medicine |
| ISBN | 0198552947 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISALENTO-991000214579707536 |
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Halliwell, Barry
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| Oxford : Clarendon Press, 1989 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. del Salento | ||
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Principles of redox signaling / / Henry Jay Forman
| Principles of redox signaling / / Henry Jay Forman |
| Autore | Forman Henry Jay |
| Pubbl/distr/stampa | London, : Henry Stewart Talks, 2023 |
| Descrizione fisica | 1 online resource (1 streaming video file (24 min.) : color, sound) |
| Collana | The biomedical & life sciences collection |
| Soggetto topico |
Active oxygen - Physiological effect
Cellular signal transduction Free radicals (Chemistry) - Physiological effect Oxidation, Physiological Oxidation-reduction reaction Amides Glutathione Hydrogen Peroxide - metabolism Oxidation-Reduction Oxidative Stress Peroxidases - metabolism Peroxides Reactive Oxygen Species - metabolism Signal Transduction - physiology Sulfhydryl Compounds Superoxides Thioredoxins |
| Formato | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents: Principles of redox signaling -- Physiological redox signaling versus oxidative stress responses -- Signaling by endogenously generated H2O2 -- NOX complexes and superoxide production -- H2O2 as a second messenger -- Glutathione (GSH) in peroxide metabolism -- Thioredoxin in peroxide metabolism -- Glutathionylation -- Oxidation of the thiol form -- Sulfenyl amides. |
| Record Nr. | UNINA-9910909153503321 |
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Forman Henry Jay
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| London, : Henry Stewart Talks, 2023 | ||
| Videoregistrazioni | ||
| Lo trovi qui: Univ. Federico II | ||
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Reactive drug metabolites [[electronic resource] /] / Amit S. Kalgutkar ...[et. al.]
| Reactive drug metabolites [[electronic resource] /] / Amit S. Kalgutkar ...[et. al.] |
| Autore | Kalgutkar Amit S. <1965-> |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2012 |
| Descrizione fisica | 1 online resource (403 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | KalgutkarAmit S. <1965-> |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Drugs - Metabolism |
| ISBN |
3-527-65574-3
1-283-60402-7 9786613916471 3-527-65576-X 3-527-65577-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Reactive Drug Metabolites; Contents; Preface; A Personal Foreword; 1 Origin and Historical Perspective on Reactive Metabolites; Abbreviations; 1.1 Mutagenesis and Carcinogenesis; 1.2 Detection of Reactive Metabolites; 1.3 Induction and Inhibition: Early Probes for Reactive Metabolites and Hepatotoxicants; 1.4 Covalent Binding and Oxidative Stress: Possible Mechanisms of Reactive Metabolite Cytotoxicity; 1.5 Activation and Deactivation: Intoxication and Detoxification; 1.6 Genetic Influences on Reactive Metabolite Formation
1.7 Halothane: the Role of Reactive Metabolites in Immune-Mediated Toxicity1.8 Formation of Reactive Metabolites, Amount Formed, and Removal of Liability; 1.9 Antibodies: Possible Clues but Inconclusive; 1.10 Parent Drug and Not Reactive Metabolites, Complications in Immune-Mediated Toxicity; 1.11 Reversible Pharmacology Should not be Ignored as a Primary Cause of Side Effects; 1.12 Conclusions: Key Points in the Introduction; References; 2 Role of Reactive Metabolites in Genotoxicity; Abbreviations; 2.1 Introduction; 2.2 Carcinogenicity of Aromatic and Heteroaromatic Amines 2.3 Carcinogenicity of Nitrosamines2.4 Carcinogenicity of Quinones and Related Compounds; 2.5 Carcinogenicity of Furan; 2.6 Carcinogenicity of Vinyl Halides; 2.7 Carcinogenicity of Ethyl Carbamate; 2.8 Carcinogenicity of Dihaloalkanes; 2.9 Assays to Detect Metabolism-Dependent Genotoxicity in Drug Discovery; 2.10 Case Studies in Eliminating Metabolism-Based Mutagenicity in Drug Discovery Programs; References; 3 Bioactivation and Inactivation of Cytochrome P450 and Other Drug-Metabolizing Enzymes; Abbreviations; 3.1 Introduction 3.2 Pharmacokinetic and Enzyme Kinetic Principles Underlying Mechanism-Based Inactivation and Drug-Drug Interactions3.2.1 Enzyme Kinetic Principles of Mechanism-Based Inactivation; 3.2.2 Pharmacokinetic Principles Underlying DDIs Caused by Mechanism-Based Inactivation; 3.3 Mechanisms of Inactivation of Cytochrome P450 Enzymes; 3.3.1 Quasi-Irreversible Inactivation; 3.3.2 Heme Adducts; 3.3.3 Protein Adducts; 3.4 Examples of Drugs and Other Compounds that are Mechanism-Based Inactivators of Cytochrome P450 Enzymes; 3.4.1 Amines; 3.4.2 Methylenedioxyphenyl Compounds 3.4.3 Quinones, Quinone Imines, and Quinone Methides3.4.4 Thiophenes; 3.4.5 Furans; 3.4.6 Alkynes; 3.4.7 2-Alkylimidazoles; 3.4.8 Other Noteworthy Cytochrome P450 Inactivators; 3.5 Mechanism-Based Inactivation of Other Drug-Metabolizing Enzymes; 3.5.1 Aldehyde Oxidase; 3.5.2 Monoamine Oxidases; 3.6 Concluding Remarks; References; 4 Role of Reactive Metabolites in Drug-Induced Toxicity - The Tale of Acetaminophen, Halothane, Hydralazine, and Tienilic Acid; Abbreviations; 4.1 Introduction; 4.2 Acetaminophen; 4.2.1 Metabolism of Acetaminophen; 4.2.2 Metabolic Activation of Acetaminophen 4.3 Halothane |
| Record Nr. | UNINA-9910141385203321 |
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Kalgutkar Amit S. <1965->
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| Weinheim, : Wiley-VCH, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Reactive drug metabolites [[electronic resource] /] / Amit S. Kalgutkar ...[et. al.]
| Reactive drug metabolites [[electronic resource] /] / Amit S. Kalgutkar ...[et. al.] |
| Autore | Kalgutkar Amit S. <1965-> |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2012 |
| Descrizione fisica | 1 online resource (403 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) | KalgutkarAmit S. <1965-> |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Free radicals (Chemistry) - Physiological effect
Drugs - Metabolism |
| ISBN |
3-527-65574-3
1-283-60402-7 9786613916471 3-527-65576-X 3-527-65577-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Reactive Drug Metabolites; Contents; Preface; A Personal Foreword; 1 Origin and Historical Perspective on Reactive Metabolites; Abbreviations; 1.1 Mutagenesis and Carcinogenesis; 1.2 Detection of Reactive Metabolites; 1.3 Induction and Inhibition: Early Probes for Reactive Metabolites and Hepatotoxicants; 1.4 Covalent Binding and Oxidative Stress: Possible Mechanisms of Reactive Metabolite Cytotoxicity; 1.5 Activation and Deactivation: Intoxication and Detoxification; 1.6 Genetic Influences on Reactive Metabolite Formation
1.7 Halothane: the Role of Reactive Metabolites in Immune-Mediated Toxicity1.8 Formation of Reactive Metabolites, Amount Formed, and Removal of Liability; 1.9 Antibodies: Possible Clues but Inconclusive; 1.10 Parent Drug and Not Reactive Metabolites, Complications in Immune-Mediated Toxicity; 1.11 Reversible Pharmacology Should not be Ignored as a Primary Cause of Side Effects; 1.12 Conclusions: Key Points in the Introduction; References; 2 Role of Reactive Metabolites in Genotoxicity; Abbreviations; 2.1 Introduction; 2.2 Carcinogenicity of Aromatic and Heteroaromatic Amines 2.3 Carcinogenicity of Nitrosamines2.4 Carcinogenicity of Quinones and Related Compounds; 2.5 Carcinogenicity of Furan; 2.6 Carcinogenicity of Vinyl Halides; 2.7 Carcinogenicity of Ethyl Carbamate; 2.8 Carcinogenicity of Dihaloalkanes; 2.9 Assays to Detect Metabolism-Dependent Genotoxicity in Drug Discovery; 2.10 Case Studies in Eliminating Metabolism-Based Mutagenicity in Drug Discovery Programs; References; 3 Bioactivation and Inactivation of Cytochrome P450 and Other Drug-Metabolizing Enzymes; Abbreviations; 3.1 Introduction 3.2 Pharmacokinetic and Enzyme Kinetic Principles Underlying Mechanism-Based Inactivation and Drug-Drug Interactions3.2.1 Enzyme Kinetic Principles of Mechanism-Based Inactivation; 3.2.2 Pharmacokinetic Principles Underlying DDIs Caused by Mechanism-Based Inactivation; 3.3 Mechanisms of Inactivation of Cytochrome P450 Enzymes; 3.3.1 Quasi-Irreversible Inactivation; 3.3.2 Heme Adducts; 3.3.3 Protein Adducts; 3.4 Examples of Drugs and Other Compounds that are Mechanism-Based Inactivators of Cytochrome P450 Enzymes; 3.4.1 Amines; 3.4.2 Methylenedioxyphenyl Compounds 3.4.3 Quinones, Quinone Imines, and Quinone Methides3.4.4 Thiophenes; 3.4.5 Furans; 3.4.6 Alkynes; 3.4.7 2-Alkylimidazoles; 3.4.8 Other Noteworthy Cytochrome P450 Inactivators; 3.5 Mechanism-Based Inactivation of Other Drug-Metabolizing Enzymes; 3.5.1 Aldehyde Oxidase; 3.5.2 Monoamine Oxidases; 3.6 Concluding Remarks; References; 4 Role of Reactive Metabolites in Drug-Induced Toxicity - The Tale of Acetaminophen, Halothane, Hydralazine, and Tienilic Acid; Abbreviations; 4.1 Introduction; 4.2 Acetaminophen; 4.2.1 Metabolism of Acetaminophen; 4.2.2 Metabolic Activation of Acetaminophen 4.3 Halothane |
| Record Nr. | UNINA-9910830512703321 |
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Kalgutkar Amit S. <1965->
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| Weinheim, : Wiley-VCH, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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