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2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics (ICDL) / / Institute of Electrical and Electronics Engineers (IEEE)
2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics (ICDL) / / Institute of Electrical and Electronics Engineers (IEEE)
Pubbl/distr/stampa Piscataway, New Jersey : , : Institute of Electrical and Electronics Engineers (IEEE), , 2013
Descrizione fisica 1 online resource (various pagings) : illustrations
Disciplina 591.18
Soggetto topico Developmental neurophysiology
Epigenetics
Robotics
ISBN 1-4799-1036-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti 2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics
Development and Learning and Epigenetic Robotics
Record Nr. UNISA-996279298703316
Piscataway, New Jersey : , : Institute of Electrical and Electronics Engineers (IEEE), , 2013
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Lo trovi qui: Univ. di Salerno
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2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics (ICDL) / / Institute of Electrical and Electronics Engineers (IEEE)
2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics (ICDL) / / Institute of Electrical and Electronics Engineers (IEEE)
Pubbl/distr/stampa Piscataway, New Jersey : , : Institute of Electrical and Electronics Engineers (IEEE), , 2013
Descrizione fisica 1 online resource (various pagings) : illustrations
Disciplina 591.18
Soggetto topico Developmental neurophysiology
Epigenetics
Robotics
ISBN 1-4799-1036-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti 2013 IEEE Third Joint International Conference on Development and Learning and Epigenetic Robotics
Development and Learning and Epigenetic Robotics
Record Nr. UNINA-9910132410103321
Piscataway, New Jersey : , : Institute of Electrical and Electronics Engineers (IEEE), , 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Aging : How Science Works / / by Carsten Carlberg, Stine M. Ulven, Eunike Velleuer
Aging : How Science Works / / by Carsten Carlberg, Stine M. Ulven, Eunike Velleuer
Autore Carlberg Carsten
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (184 pages)
Disciplina 572
Altri autori (Persone) UlvenStine M
VelleuerEunike
Soggetto topico Molecular biology
Epigenetics
Nutrition
Molecular Evolution
Cancer
Metabolism
Molecular Biology
Cancer Biology
ISBN 3-031-61257-4
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. The human genome, development and evolution -- 2. Gene expression and epigenetics -- 3. Epigenetics and aging -- 4. Molecular and cellular basis of aging -- 5. Nutrition and aging -- 6. Aging and immunity -- 7. Central role of aging during chronic diseases -- 8. Aging and cancer -- 9. Healthy aging.
Record Nr. UNINA-9910874669703321
Carlberg Carsten  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024
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Alterations of epigenetics and microRNAs in cancer and cancer stem cell [[electronic resource] /] / topic editor: Yoshimasa Saito
Alterations of epigenetics and microRNAs in cancer and cancer stem cell [[electronic resource] /] / topic editor: Yoshimasa Saito
Autore Yoshimasa Saito
Pubbl/distr/stampa Frontiers Media SA, 2014
Descrizione fisica 1 online resource (79 pages) : illustrations; digital, PDF file(s)
Disciplina 616.99
Collana Frontiers in research topics
Frontiers in genetics
Soggetto topico Epigenetics
Stem cells
Genetics
Cancer - Treatment - Research
Soggetto non controllato MicroRNAs
cancer stem cells
Methylation
epigenetics
Cancer
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Alterations of epigenetics and microRNAs in cancer and cancer stem cell / Yoshimasa Saito -- Culturing intestinal stem cells: applications for colorectal cancer research / Masayuki Fuji and Toshiro Sato -- Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis / Mohammadreza Hajjari, Atefeh Khoshnevisan and Bernardo Lemos -- Multilayer-omics analyses of human cancers: exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium / Yae Kanai and Eri Arai -- Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation / Keisuke Katsushima and Yutaka Kondo -- Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation / Yasuko Kikuchi, Eiichi Tsuji, Koichi Yagi, Keisuke Matsusaka, Shingo Tsuji, Junichi Kurebayashi, Toshihisa Ogawa, Hiroyuki Aburatani, Atsushi Kaneda -- MicroRNAs in Barrett's esophagus: future prospects / Juntaro Matsuzaki and Hidekazu Suzuki -- Epigenetic alteration and microRNA dysregulation in cancer / Hiromu Suzuki, Reo Maruyama, Eiichiro Yamamoto and Masahiro Kai -- The role of microRNAs in the regulation of cancer stem cells / Ryou-u Takahashi, Hiroaki Miyazaki and Takahiro Ochiya -- Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes / Kousuke Watanabe and Daiya Takai -- The role of mesenchymal stem cell in cancer development / Hiroshi Yagi and Yuko Kitagawa.
Record Nr. UNINA-9910136405603321
Yoshimasa Saito  
Frontiers Media SA, 2014
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Lo trovi qui: Univ. Federico II
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Cancer Epigenetics / / edited by Rasime Kalkan
Cancer Epigenetics / / edited by Rasime Kalkan
Edizione [First edition.]
Pubbl/distr/stampa Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023]
Descrizione fisica 1 online resource (389 pages)
Disciplina 616.99/4042
Collana Epigenetics and Human Health Series
Soggetto topico Cancer - Genetic aspects
Epigenetics
Neoplasms - genetics
Epigenomics
Epigenesis, Genetic
ISBN 3-031-42365-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Contents -- About the Editor -- List of Contributors -- Abbreviations -- Part-I: Background -- Chapter 1: An Overview of Epigenetics Modifications in Normal and Cancer Cell -- 1.1 Introduction -- 1.1.1 DNA Methylation -- 1.1.2 DNA Hydroxymethylation -- 1.1.3 Histone Modifications -- 1.1.4 Nucleosome Remodeling -- 1.1.5 Non-coding RNAs -- 1.2 Epigenetics in Normal Cell -- 1.2.1 DNA Methylation in Normal Cell -- 1.2.2 DNA Hydroxymethylation in Normal Cell -- 1.2.3 Histone Modifications in Normal Cell -- 1.2.4 Nucleosome Remodeling in Normal Cell -- 1.2.5 Non-coding RNAs in Normal Cell -- 1.3 Epigenetics in Cancer Cell -- 1.3.1 DNA Methylation in Cancer Cell -- 1.3.2 DNA Hydroxymethylation in Cancer Cell -- 1.3.3 Histone Modifications in Cancer Cell -- 1.3.4 Nucleosome Remodeling in Cancer Cell -- 1.3.5 Non-coding RNAs in Cancer Cell -- 1.4 Conclusion -- References -- Chapter 2: Epigenetic Enzymes and Their Mutations in Cancer -- 2.1 Introduction -- 2.1.1 DNA Methylation -- 2.1.1.1 DNA Methyltransferase 1 -- 2.1.1.2 DNA Methyltransferase 3 -- 2.1.1.3 Mutations of DNA Methyltransferases -- 2.1.1.4 Ten Eleven Translocation Proteins -- 2.1.1.5 Mutations of Ten Eleven Translocation Proteins -- 2.1.2 Histone Modifications -- 2.1.2.1 Histone Acetyltransferases -- 2.1.2.2 Mutations of Histone Acetyltransferases -- 2.1.2.3 Histone Deacetylases -- 2.1.2.4 Mutations of Histone Deacetylases -- 2.1.2.5 Histone Methyltransferases -- 2.1.2.6 Mutations of Histone Methyltransferases -- 2.1.2.7 Histone Demethylases -- 2.1.2.8 Mutations of Histone Demethylases -- 2.2 Conclusion -- References -- Chapter 3: Introduction to Cancer Epigenetics -- 3.1 Introduction -- 3.1.1 History of Epigenetics -- 3.1.2 Epigenetics and Epigenome -- 3.2 Epigenetic Machinery -- 3.2.1 DNA Methylation -- 3.2.1.1 DNA Methyltransferases.
3.2.1.2 Methyl-CpG Recognition Proteins -- 3.2.1.3 5-Hydroxymethyl Cytosine and TET Enzymes -- 3.2.1.4 TET Proteins and DNA Demethylation -- 3.2.2 Abnormal Epigenomic Reprogramming in Cancer -- 3.2.2.1 Cancer-Specific DNA Methylation Alterations -- 3.2.2.2 Global DNA Hypomethylation -- 3.2.2.2.1 DNA Methyltransferases (DNMTs) and DNA Methylation -- 3.2.2.2.2 Focal DNA Hypermethylation and Tumor Suppressor Genes -- 3.2.2.2.3 Roles of DNA Methylation Aberrations in Cell Proliferation -- 3.2.2.2.4 Role of DNA Methylation Changes in Evasion of Apoptosis -- 3.2.2.2.5 Promotion of Genome Instability by DNA Methylation Alterations -- 3.2.3 Histon Modifications in Cancer -- 3.2.3.1 Histone Acetylation -- 3.2.3.2 Histone Methylation -- 3.2.3.3 Histone Ubiquitination -- 3.2.3.4 Histone Phosphorylation -- 3.2.3.5 Other Modifications -- 3.2.4 Chromatin Remodelers -- 3.2.5 miRNAs in Cancer -- 3.2.5.1 miRNA Biogenesis and Functions -- 3.2.5.1.1 Canonical miRNA Biogenesis -- 3.2.5.1.2 Non-canonical miRNA Biogenesis -- 3.2.6 The Role of miRNA in Cancer -- 3.2.6.1 Proliferation and miRNAs in Cancer -- 3.2.6.2 Apoptosis and miRNAs in Cancer -- 3.2.6.3 Invasion, Metastasis, and miRNAs in Cancer -- 3.2.6.4 Angiogenesis and miRNAs in Cancer -- 3.2.6.5 Non-canonical Function of miRNA in Cancer -- 3.2.6.6 Deregulation of miRNA Expression in Cancer -- 3.2.7 Circulating miRNA in Cancer -- 3.2.8 miRNA-based Biomarkers in Cancer -- 3.2.9 miRNA-Based Therapies in Cancer -- 3.2.9.1 Approaches for miRNA Therapeutic Delivery -- 3.3 Conclusion -- References -- Part II: Cancer Specific Epigenetic Alterations -- Chapter 4: Epigenetics in the Diagnosis, Prognosis, and Therapy of Cancer -- 4.1 Epigenetics and Cancer -- 4.1.1 Histone Modification -- 4.1.2 DNA Methylation -- 4.1.3 Noncoding RNAs -- 4.1.4 Chromatin Remodeling -- 4.2 Epigenetics in Cancer Diagnosis.
4.2.1 DNA Methylation as a Biomarker of Cancer Diagnosis -- 4.2.2 Histone Modification as a Biomarker of Cancer Diagnosis -- 4.2.3 Non-encoding RNAs as Biomarkers of Cancer Diagnosis -- 4.2.4 Imprinted Genes as Biomarkers of Cancer Diagnosis -- 4.3 Epigenetic in Cancer Prognosis -- 4.3.1 DNA Methylation in Cancer Prognosis -- 4.3.2 Histone Modifications in Cancer Prognosis -- 4.3.3 Histone Variants and Chromatin Remodeling in Cancer Prognosis -- 4.3.4 Noncoding RNAs in Cancer Prognosis -- 4.4 Epigenetics in Cancer Therapy -- 4.4.1 Targeting DNA Methylation-Related Enzymes in Cancer Treatment -- 4.4.2 Targeting Histone Acetylation-Related Enzymes in Cancer Treatment -- 4.4.3 Targeting Other Epigenetic Biomarkers in Cancer Treatment -- 4.5 Conclusions and Perspectives -- References -- Chapter 5: Clinical Studies and Epi-Drugs in Various Cancer Types -- 5.1 Introduction -- 5.2 Epigenetic Studies Regarding the Most Common Solid Tumor Types -- 5.2.1 Lung Cancer -- 5.2.2 Breast Cancer -- 5.2.3 Colorectal Cancer -- 5.2.4 Prostate Cancer -- 5.2.5 Cutaneous Melanoma -- 5.2.6 Epigenetic Studies Regarding the Most Common Hematological Malignancies -- 5.2.6.1 Myeloid Leukemias -- 5.2.6.2 Lymphoid Leukemias -- 5.2.6.3 Lymphomas -- 5.3 Conclusion -- References -- Chapter 6: Epigenetic Regulation in Breast Cancer Tumor Microenvironment -- 6.1 Introduction -- 6.2 Tumor Microenvironment in Breast Cancer -- 6.2.1 Tumor-Associated Macrophages (TAMs) -- 6.2.2 Helper T Cells and Cytotoxic T Cells -- 6.2.3 Natural Killer Cells (NK Cells) -- 6.2.4 Dendritic Cells (DCs) -- 6.2.5 Myeloid-Derived Suppressor Cells (MDSCs) -- 6.2.6 Cancer-Associated Fibroblasts (CAFs) -- 6.2.7 Endothelial Cells -- 6.2.8 Cytokines and Chemokines -- 6.3 Epigenetic Modifications in Breast Cancer Tumor Microenvironment -- 6.3.1 DNA Methylation -- 6.3.2 Histone Modifications.
6.3.3 NcRNA-mediated Gene Silencing -- 6.4 Epigenetic Modulators in the Tumor Microenvironment of Breast Cancer -- 6.5 Conclusion -- References -- Chapter 7: The Epigenetics of Brain Tumors: Fundamental Aspects of Epigenetics in Glioma -- 7.1 Introduction -- 7.2 Overview of Epigenetic Mechanisms -- 7.2.1 DNA Methylation -- 7.2.1.1 DNA Demethylation and Hypermethylated Phenotype -- 7.2.2 Posttranslational Modifications of Histones -- 7.2.3 Noncoding RNAs -- 7.3 Epigenetic Changes in Gliomas -- 7.3.1 Glioma CpG Island Methylator Phenotype (G-CIMP) -- 7.3.2 IDH1 Mutations and Relationship to Epigenetic Changes in Gliomas -- 7.3.2.1 IDH1 and IDH2 Genes -- 7.3.2.2 Classifying Marker 1p/19q Codeletion -- 7.3.2.3 MGMT Promoter Methylation -- 7.3.2.4 IDHs, G-CIMP Status, and MGMT Promoter Methylation Relations -- 7.4 Epigenetic Biomarkers Related with Chromatin Modifications -- 7.4.1 CTCF (CCCTC-Binding Factor) -- 7.4.2 Nuclear Alpha-Thalassemia/Mental Retardation X-Linked Syndrome (ATRX) Gene -- 7.5 Histone Modifications -- 7.5.1 Histone Acetylation -- 7.5.2 Histone Methylation and Pediatric Gliomas -- 7.6 Noncoding RNA and Glial Tumors -- 7.7 Conclusion -- References -- Chapter 8: Epigenetic Alterations in Pancreatic Cancer -- 8.1 Introduction -- 8.2 Genetic Alterations in Pancreatic Cancer -- 8.3 Epigenetic Events in Pancreatic Cancer -- 8.3.1 DNA Methylation -- 8.3.2 Histone Modification -- 8.3.2.1 Lysine Residue-Specific Methylation -- 8.3.2.2 Lysine-Specific Demethylation -- 8.3.2.3 Arginine-Specific Methylation -- 8.4 Conclusion -- References -- Chapter 9: Current Preclinical Applications of Pharmaco-Epigenetics in Cardiovascular Diseases -- 9.1 Cardiovascular Diseases: From Ischemic Injuries to Heart Repair -- 9.2 The Impact of Epigenetics on Cardiovascular Activity -- 9.3 Epigenetic Machinery in Cardiovascular Diseases.
9.3.1 DNA Methylation Role in CVD -- 9.3.2 Histone Modifications in CVD -- 9.3.3 Histone Deacetylases in CVD -- 9.3.4 Histone Methylation in CVD -- 9.3.5 Noncoding RNAS in CVD -- 9.4 Epigenetic Dysregulation and Cardiovascular Disease Susceptibility. -- 9.5 Epigenetic Biomarkers in Cardiovascular Diseases -- 9.5.1 Epigenetic Biomarkers in MI -- 9.5.2 Epigenetic Biomarkers in HF -- 9.5.3 Epi-Biomarkers in Arrhythmia -- 9.6 Preclinical Evidence of Pharmaco-Epigenetic Role in Cardiovascular Diseases -- 9.6.1 Histone Modifications -- 9.6.2 DNA Methylation -- 9.6.3 Noncoding RNA -- 9.7 Epigenetic-Based Therapies in Cardiovascular Diseases and Future Perspectives -- 9.8 Potential Effects of Existing Drugs on Epigenetic Modulators in Cardiovascular Disease -- References -- Chapter 10: Epigenetic Alterations in Colorectal Cancer -- 10.1 Introduction -- 10.2 Aberrant DNA Methylation -- 10.2.1 DNA Methylation Alterations in Colorectal Cancer (CRC) -- 10.2.1.1 Hypermethylation -- 10.2.1.2 Hypomethylation -- 10.2.2 DNA Methylation and the Pathogenesis of Colorectal Cancer: ``Traditional´´ and ``Serrated´´ Polyp Pathways -- 10.2.3 Clinical Applications of DNA methylation in Colorectal Cancer -- 10.2.3.1 Stool-Based Biomarkers -- 10.2.3.2 Blood-Based Biomarkers -- 10.2.3.3 Epigenetic Prognostic Biomarkers -- 10.2.3.4 Epigenetic Predictive Biomarkers for Response to Treatment -- 10.2.3.5 Colorectal Cancer and ``Field Cancerization´´ -- 10.2.4 Chromatin Alterations and Histone Modifications -- 10.2.4.1 Overview of Histone Biology -- 10.2.4.2 Histone Modification Alterations in Colorectal Cancer and Potential for Clinical Applications -- 10.2.5 microRNA and Colorectal Cancer -- 10.2.5.1 Overview of miRNA Biology -- 10.2.5.2 Dysregulation of miRNA Expression in ``Traditional´´ and ``Serrated´´ Pathways -- 10.2.6 miRNAs as Diagnostic Biomarkers in Colorectal Cancer.
10.2.6.1 Blood-Based Biomarkers.
Record Nr. UNINA-9910768191303321
Cham, Switzerland : , : Springer Nature Switzerland AG, , [2023]
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Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Autore Kyriazis M.
Pubbl/distr/stampa Sharjah, UAE : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (270 pages)
Disciplina 612.67
Collana Frontiers in aging sciences
Soggetto topico Aging - Physiological aspects
Hormesis
Epigenetics
Soggetto genere / forma Electronic books.
ISBN 1-68108-335-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910493709903321
Kyriazis M.  
Sharjah, UAE : , : Bentham Science Publishers, , 2016
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Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Autore Kyriazis M.
Pubbl/distr/stampa Sharjah, UAE : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (270 pages)
Disciplina 612.67
Collana Frontiers in aging sciences
Soggetto topico Aging - Physiological aspects
Hormesis
Epigenetics
ISBN 1-68108-335-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910798733903321
Kyriazis M.  
Sharjah, UAE : , : Bentham Science Publishers, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Challenging aging : the anti-senescence effects of hormesis, environmental enrichment and information exposure / / by Marios Kyriazis
Autore Kyriazis M.
Pubbl/distr/stampa Sharjah, UAE : , : Bentham Science Publishers, , 2016
Descrizione fisica 1 online resource (270 pages)
Disciplina 612.67
Collana Frontiers in aging sciences
Soggetto topico Aging - Physiological aspects
Hormesis
Epigenetics
ISBN 1-68108-335-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910817089403321
Kyriazis M.  
Sharjah, UAE : , : Bentham Science Publishers, , 2016
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Chromatin and Epigenetics / / edited by Colin Logie and Tobias Aurelius Knoch
Chromatin and Epigenetics / / edited by Colin Logie and Tobias Aurelius Knoch
Pubbl/distr/stampa London : , : IntechOpen, , 2020
Descrizione fisica 1 online resource (ix, 263 pages) : illustrations
Disciplina 572.87
Soggetto topico Epigenetics
Chromatin
ISBN 1-78984-493-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910407757503321
London : , : IntechOpen, , 2020
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Chromatin and epigenetics / / edited by Colin Logie, Tobias Aurelius Knoch
Chromatin and epigenetics / / edited by Colin Logie, Tobias Aurelius Knoch
Pubbl/distr/stampa London : , : IntechOpen, , 2020
Descrizione fisica 1 online resource (294 pages)
Disciplina 572.87
Soggetto topico Chromatin
Epigenetics
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Logic of Epigenetics and Investigation of Potential Gene Regions -- 2. Recognition of Nucleosomes by Chromatin Factors: Lessons from Data-Driven Docking-Based Structures of Nucleosome-Protein Complexes -- 3. Chromatin Dynamics upon DNA Damage -- 4. A Consistent Systems Mechanics Model of the 3D Architecture and Dynamics of Genomes -- 5. Apicomplexa and Histone Variants: What's New? -- 6. Epigenetic Modulation of Circadian Rhythms: Bmal1 Gene Regulation -- 7. Epigenome Editing -- 8. Resetting Cell Fate by Epigenetic Reprogramming -- 9. Cytosine Modifications and Distinct Functions of TET1 on Tumorigenesis -- 10. Role of COX-2 Promoter Methylation and Helicobacter pylori Infection in Impaired Gastric Ulcer Healing -- 11. Epigenetic Regulation of Hepatitis B Virus Replication -- 12. Part 1: The PIWI-piRNA Pathway Is an Immune-Like Surveillance Process That Controls Genome Integrity by Silencing Transposable Elements -- 13. Part 2: Deregulated Expressions of PIWI Proteins and piRNAs as New Candidate Biomarkers and Potential Therapeutic Tools in Cancer.
Record Nr. UNINA-9910688592403321
London : , : IntechOpen, , 2020
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