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Advances in enzymology and related areas of molecular biology . Volume 77 / / founded by F. F. Nord ; edited by Eric J. Toone
Advances in enzymology and related areas of molecular biology . Volume 77 / / founded by F. F. Nord ; edited by Eric J. Toone
Autore Nord F. F.
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2011]
Descrizione fisica 1 online resource (442 p.)
Disciplina 572.7
Collana Advances in enzymology and related areas of molecular biology
Soggetto topico Enzymes - Synthesis
Enzymes - Industrial applications
Soggetto genere / forma Electronic books.
ISBN 0-470-92293-1
1-283-02543-4
9786613025432
0-470-92052-1
0-470-92054-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY; CONTENTS; CONTRIBUTORS; PREFACE; STRUCTURE AND MECHANISM OF RND-TYPE MULTIDRUG EFFLUX PUMPS; EFFLUX PUMPS OF GRAM-NEGATIVE BACTERIA: GENETIC RESPONSES TO STRESS AND THE MODULATION OF THEIR ACTIVITY BY pH, INHIBITORS, AND PHENOTHIAZINES; EFFLUX PUMPS OF THE RESISTANCE-NODULATION-DIVISION FAMILY: A PERSPECTIVE OF THEIR STRUCTURE, FUNCTION, AND REGULATION IN GRAM-NEGATIVE BACTERIA; THE MFS EFFLUX PROTEINS OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA; EFFLUX PUMPS AS AN IMPORTANT MECHANISM FOR QUINOLONE RESISTANCE
XENOBIOTIC EFFLUX IN BACTERIA AND FUNGI: A GENOMICS UPDATEA SURVEY OF OXIDATIVE PARACATALYTIC REACTIONS CATALYZED BY ENZYMES THAT GENERATE CARBANIONIC INTERMEDIATES: IMPLICATIONS FOR ROS PRODUCTION, CANCER ETIOLOGY, AND NEURODEGENERATIVE DISEASES; AUTHOR I NDEX; SUBJECT INDEX; COLOUR PLATES
Record Nr. UNINA-9910133587303321
Nord F. F.  
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in enzymology and related areas of molecular biology . Volume 77 / / founded by F. F. Nord ; edited by Eric J. Toone
Advances in enzymology and related areas of molecular biology . Volume 77 / / founded by F. F. Nord ; edited by Eric J. Toone
Autore Nord F. F.
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2011]
Descrizione fisica 1 online resource (442 p.)
Disciplina 572.7
Collana Advances in enzymology and related areas of molecular biology
Soggetto topico Enzymes - Synthesis
Enzymes - Industrial applications
ISBN 0-470-92293-1
1-283-02543-4
9786613025432
0-470-92052-1
0-470-92054-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY; CONTENTS; CONTRIBUTORS; PREFACE; STRUCTURE AND MECHANISM OF RND-TYPE MULTIDRUG EFFLUX PUMPS; EFFLUX PUMPS OF GRAM-NEGATIVE BACTERIA: GENETIC RESPONSES TO STRESS AND THE MODULATION OF THEIR ACTIVITY BY pH, INHIBITORS, AND PHENOTHIAZINES; EFFLUX PUMPS OF THE RESISTANCE-NODULATION-DIVISION FAMILY: A PERSPECTIVE OF THEIR STRUCTURE, FUNCTION, AND REGULATION IN GRAM-NEGATIVE BACTERIA; THE MFS EFFLUX PROTEINS OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA; EFFLUX PUMPS AS AN IMPORTANT MECHANISM FOR QUINOLONE RESISTANCE
XENOBIOTIC EFFLUX IN BACTERIA AND FUNGI: A GENOMICS UPDATEA SURVEY OF OXIDATIVE PARACATALYTIC REACTIONS CATALYZED BY ENZYMES THAT GENERATE CARBANIONIC INTERMEDIATES: IMPLICATIONS FOR ROS PRODUCTION, CANCER ETIOLOGY, AND NEURODEGENERATIVE DISEASES; AUTHOR I NDEX; SUBJECT INDEX; COLOUR PLATES
Record Nr. UNINA-9910830364903321
Nord F. F.  
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2011]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Pubbl/distr/stampa Hoboken, New Jersey, : Wiley, 2009
Descrizione fisica 1 online resource (296 p.)
Disciplina 572.654
612.0151
Altri autori (Persone) TooneEric J
Collana Advances in enzymology and related areas of molecular biology
Soggetto topico Enzymes - Metabolism
Enzymes - Industrial applications
Enzymes - Synthesis
Soggetto genere / forma Electronic books.
ISBN 1-282-11273-2
9786612112737
0-470-39288-6
0-470-39287-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY Volume 76; CONTENTS; Contributors; Preface; Inosine 5 ́-Monophosphate Dehydrogenase; Natural Product Glycosyltransferases: Properties and Applications; Combinatorial and Evolutionary Design of Biosynthetic Reaction Sequences; Trends in Microbial Synthesis of Natural Products and Biofuels; Author Index; Subject Index
Record Nr. UNINA-9910146408503321
Hoboken, New Jersey, : Wiley, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Pubbl/distr/stampa Hoboken, New Jersey, : Wiley, 2009
Descrizione fisica 1 online resource (296 p.)
Disciplina 572.654
612.0151
Altri autori (Persone) TooneEric J
Collana Advances in enzymology and related areas of molecular biology
Soggetto topico Enzymes - Metabolism
Enzymes - Industrial applications
Enzymes - Synthesis
ISBN 1-282-11273-2
9786612112737
0-470-39288-6
0-470-39287-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY Volume 76; CONTENTS; Contributors; Preface; Inosine 5 ́-Monophosphate Dehydrogenase; Natural Product Glycosyltransferases: Properties and Applications; Combinatorial and Evolutionary Design of Biosynthetic Reaction Sequences; Trends in Microbial Synthesis of Natural Products and Biofuels; Author Index; Subject Index
Record Nr. UNINA-9910830667003321
Hoboken, New Jersey, : Wiley, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Advances in enzymology and related areas of molecular biology . Volume 76 [[electronic resource] /] / edited by Eric J. Toone
Pubbl/distr/stampa Hoboken, New Jersey, : Wiley, 2009
Descrizione fisica 1 online resource (296 p.)
Disciplina 572.654
612.0151
Altri autori (Persone) TooneEric J
Collana Advances in enzymology and related areas of molecular biology
Soggetto topico Enzymes - Metabolism
Enzymes - Industrial applications
Enzymes - Synthesis
ISBN 1-282-11273-2
9786612112737
0-470-39288-6
0-470-39287-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY Volume 76; CONTENTS; Contributors; Preface; Inosine 5 ́-Monophosphate Dehydrogenase; Natural Product Glycosyltransferases: Properties and Applications; Combinatorial and Evolutionary Design of Biosynthetic Reaction Sequences; Trends in Microbial Synthesis of Natural Products and Biofuels; Author Index; Subject Index
Record Nr. UNINA-9910840841003321
Hoboken, New Jersey, : Wiley, 2009
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Asymmetric organic synthesis with enzymes / / edited by Vicente Gotor, Ignacio Alfonso, and Eduardo García-Urdiales
Asymmetric organic synthesis with enzymes / / edited by Vicente Gotor, Ignacio Alfonso, and Eduardo García-Urdiales
Pubbl/distr/stampa Weinheim, Germany : , : WILEY-VCH Verlag GmbH & Co. KGaA, , 2008
Descrizione fisica 1 online resource (341 p.)
Disciplina 572.745
Soggetto topico Enzymes - Synthesis
Asymmetric synthesis
Organic compounds - Synthesis
Soggetto genere / forma Electronic books.
ISBN 1-281-94689-3
9786611946890
3-527-62248-9
3-527-62249-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Asymmetric Organic Synthesis with Enzymes; Contents; Preface; List of Contributors; I Methodology; 1 Medium Engineering; 1.1 Introduction; 1.2 Modulation of Enzyme Enantioselectivity by Medium Engineering; 1.2.1 Selectivity Enhancement by Addition of Water-Miscible Organic Cosolvents; 1.2.2 Selectivity Enhancement in Organic Media with Low Water Activity; 1.2.2.1 Organic Solvent Systems; 1.2.2.2 Enzyme Properties in Organic Solvents; 1.2.2.3 Medium Engineering; 1.2.3 Rationales; 1.2.4 Modulation of Enzyme Selectivity: New Trends of Research; 1.2.4.1 Ionic Liquids; 1.2.4.2 Additives
1.3 Conclusions and OutlooksReferences; 2 Directed Evolution as a Means to Engineer Enantioselective Enzymes; 2.1 Introduction; 2.2 Molecular Biological Methods for Mutagenesis; 2.3 High-throughput Screening Methods for Enantioselectivity; 2.4 Examples of Enhancing the Enantioselectivity of Enzymes by Directed Evolution; 2.4.1 Lipase from Pseudomonas aeruginosa (PAL); 2.4.2 Other Lipases; 2.4.3 Esterases; 2.4.4 Hydantoinases; 2.4.5 Nitrilases; 2.4.6 Epoxide Hydrolases; 2.4.7 Phosphotriesterases; 2.4.8 Aminotransferases; 2.4.9 Aldolases
2.4.10 Cyclohexanone and Cyclopentanone Monooxygenases as Baeyer-Villigerases and Sulfoxidation Catalysts2.4.11 Monoamine Oxidases; 2.4.12 Cytochrome P450 Enzymes; 2.4.13 Other Enzymes; 2.5 Conclusions and Perspectives; References; 3 The Search for New Enzymes; 3.1 Introduction; 3.2 Mechanism-based Enzyme Design; 3.2.1 Catalytic Antibodies; 3.2.2 Rational Design of New Catalysts on Enzyme and Protein Basis; 3.2.3 Synthetic Enzyme Models; 3.3 Metagenomics; 3.3.1 Construction of Metagenome-derived DNA Libraries; 3.3.1.1 Selection of the Environment; 3.3.1.2 Cloning Strategies
3.3.1.3 Screening and Detection Technologies3.3.1.4 Major Problems that Need to be Addressed; 3.3.2 The Genomes of Not Yet Cultured Microbes as Resources for Novel Genes; 3.3.2.1 Polysaccharide Degrading/Modifying Enzymes; 3.3.2.2 Lipolytic Biocatalysts; 3.3.2.3 Vitamin Biosynthesis; 3.3.2.4 Nitrilases, Nitrile Hydratases, and Amidases; 3.3.2.5 Oxidoreductases/Dehydrogenases; 3.3.2.6 Proteases; 3.3.2.7 Glycerol Hydratases; 3.3.2.8 Antibiotics and Pharmaceuticals; 3.4 Conclusion; References; II Synthetic Applications; 4 Dynamic Kinetic Resolutions; 4.1 Introduction
4.1.1 Synthesis of Enantiomerically Pure Compounds4.1.2 Kinetic Resolution (KR) and Dynamic Kinetic Resolution (DKR); 4.1.3 Enzymes in Organic Chemistry; 4.2 Metal-Catalyzed Racemization; 4.2.1 DKR of Allylic Acetates and Allylic Alcohols; 4.2.2 DKR of sec-alcohols; 4.2.3 DKR of Amines; 4.3 Base-Catalyzed Racemization; 4.3.1 DKR of Thioesters; 4.3.2 DKR of Activated Esters; 4.3.3 DKR of Oxazolones; 4.3.4 DKR of Hydantoins; 4.3.5 DKR of Acyloins; 4.4 Acid-Catalyzed Racemization; 4.5 Racemization through Continuous Reversible Formation-Cleavage of the Substrate; 4.5.1 DKR of Cyanohydrins
4.5.2 DKR of Hemithioathetals
Record Nr. UNINA-9910144229803321
Weinheim, Germany : , : WILEY-VCH Verlag GmbH & Co. KGaA, , 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Asymmetric organic synthesis with enzymes / / edited by Vicente Gotor, Ignacio Alfonso, and Eduardo García-Urdiales
Asymmetric organic synthesis with enzymes / / edited by Vicente Gotor, Ignacio Alfonso, and Eduardo García-Urdiales
Pubbl/distr/stampa Weinheim, Germany : , : WILEY-VCH Verlag GmbH & Co. KGaA, , 2008
Descrizione fisica 1 online resource (341 p.)
Disciplina 572.745
Soggetto topico Enzymes - Synthesis
Asymmetric synthesis
Organic compounds - Synthesis
ISBN 1-281-94689-3
9786611946890
3-527-62248-9
3-527-62249-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Asymmetric Organic Synthesis with Enzymes; Contents; Preface; List of Contributors; I Methodology; 1 Medium Engineering; 1.1 Introduction; 1.2 Modulation of Enzyme Enantioselectivity by Medium Engineering; 1.2.1 Selectivity Enhancement by Addition of Water-Miscible Organic Cosolvents; 1.2.2 Selectivity Enhancement in Organic Media with Low Water Activity; 1.2.2.1 Organic Solvent Systems; 1.2.2.2 Enzyme Properties in Organic Solvents; 1.2.2.3 Medium Engineering; 1.2.3 Rationales; 1.2.4 Modulation of Enzyme Selectivity: New Trends of Research; 1.2.4.1 Ionic Liquids; 1.2.4.2 Additives
1.3 Conclusions and OutlooksReferences; 2 Directed Evolution as a Means to Engineer Enantioselective Enzymes; 2.1 Introduction; 2.2 Molecular Biological Methods for Mutagenesis; 2.3 High-throughput Screening Methods for Enantioselectivity; 2.4 Examples of Enhancing the Enantioselectivity of Enzymes by Directed Evolution; 2.4.1 Lipase from Pseudomonas aeruginosa (PAL); 2.4.2 Other Lipases; 2.4.3 Esterases; 2.4.4 Hydantoinases; 2.4.5 Nitrilases; 2.4.6 Epoxide Hydrolases; 2.4.7 Phosphotriesterases; 2.4.8 Aminotransferases; 2.4.9 Aldolases
2.4.10 Cyclohexanone and Cyclopentanone Monooxygenases as Baeyer-Villigerases and Sulfoxidation Catalysts2.4.11 Monoamine Oxidases; 2.4.12 Cytochrome P450 Enzymes; 2.4.13 Other Enzymes; 2.5 Conclusions and Perspectives; References; 3 The Search for New Enzymes; 3.1 Introduction; 3.2 Mechanism-based Enzyme Design; 3.2.1 Catalytic Antibodies; 3.2.2 Rational Design of New Catalysts on Enzyme and Protein Basis; 3.2.3 Synthetic Enzyme Models; 3.3 Metagenomics; 3.3.1 Construction of Metagenome-derived DNA Libraries; 3.3.1.1 Selection of the Environment; 3.3.1.2 Cloning Strategies
3.3.1.3 Screening and Detection Technologies3.3.1.4 Major Problems that Need to be Addressed; 3.3.2 The Genomes of Not Yet Cultured Microbes as Resources for Novel Genes; 3.3.2.1 Polysaccharide Degrading/Modifying Enzymes; 3.3.2.2 Lipolytic Biocatalysts; 3.3.2.3 Vitamin Biosynthesis; 3.3.2.4 Nitrilases, Nitrile Hydratases, and Amidases; 3.3.2.5 Oxidoreductases/Dehydrogenases; 3.3.2.6 Proteases; 3.3.2.7 Glycerol Hydratases; 3.3.2.8 Antibiotics and Pharmaceuticals; 3.4 Conclusion; References; II Synthetic Applications; 4 Dynamic Kinetic Resolutions; 4.1 Introduction
4.1.1 Synthesis of Enantiomerically Pure Compounds4.1.2 Kinetic Resolution (KR) and Dynamic Kinetic Resolution (DKR); 4.1.3 Enzymes in Organic Chemistry; 4.2 Metal-Catalyzed Racemization; 4.2.1 DKR of Allylic Acetates and Allylic Alcohols; 4.2.2 DKR of sec-alcohols; 4.2.3 DKR of Amines; 4.3 Base-Catalyzed Racemization; 4.3.1 DKR of Thioesters; 4.3.2 DKR of Activated Esters; 4.3.3 DKR of Oxazolones; 4.3.4 DKR of Hydantoins; 4.3.5 DKR of Acyloins; 4.4 Acid-Catalyzed Racemization; 4.5 Racemization through Continuous Reversible Formation-Cleavage of the Substrate; 4.5.1 DKR of Cyanohydrins
4.5.2 DKR of Hemithioathetals
Record Nr. UNINA-9910830044503321
Weinheim, Germany : , : WILEY-VCH Verlag GmbH & Co. KGaA, , 2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Enzyme catalysis in organic synthesis : a comprehensive handbook
Enzyme catalysis in organic synthesis : a comprehensive handbook
Pubbl/distr/stampa [Place of publication not identified], : VCH, 1995
Disciplina 574.19/25
Soggetto topico Enzymes - Synthesis
Organic compounds - Industrial applications
Enzymes
Animal Biochemistry
Human Anatomy & Physiology
Health & Biological Sciences
ISBN 3-527-61942-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNISA-996197428103316
[Place of publication not identified], : VCH, 1995
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Enzyme-based organic synthesis / / Cheanyeh Cheng
Enzyme-based organic synthesis / / Cheanyeh Cheng
Autore Cheng Cheanyeh
Pubbl/distr/stampa Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022]
Descrizione fisica 1 online resource (545 pages)
Disciplina 660.2995
Soggetto topico Biocatalysis
Enzymes - Biotechnology
Enzymes - Synthesis
Soggetto genere / forma Electronic books.
ISBN 1-118-99515-5
1-118-99514-7
1-118-99516-3
9781118995150
9781118995143
9781118027943
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910554826103321
Cheng Cheanyeh  
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Enzyme-based organic synthesis / / Cheanyeh Cheng
Enzyme-based organic synthesis / / Cheanyeh Cheng
Autore Cheng Cheanyeh
Pubbl/distr/stampa Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022]
Descrizione fisica 1 online resource (545 pages)
Disciplina 660.2995
Soggetto topico Biocatalysis
Enzymes - Biotechnology
Enzymes - Synthesis
ISBN 1-118-99515-5
1-118-99514-7
1-118-99516-3
9781118995150
9781118995143
9781118027943
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910831197703321
Cheng Cheanyeh  
Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui