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Environmental chemicals, enzyme function, and human disease
| Environmental chemicals, enzyme function, and human disease |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica |
| Descrizione fisica | 1 online resource (392 pages) |
| Disciplina | 615.9 |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Toxicology
Drugs - Metabolism Enzyme induction Biotransformation (Metabolism) |
| ISBN |
1-280-78392-3
9786613694317 0-470-72059-X 0-470-71827-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Environmental Chemicals Enzyme Function and Human Disease; Contents; Chairman's introduction; The role of the drug-metabolizing enzymes; Discussion; The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver; Discussion; Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues; Discussion; Induction of enzymes involved in DNA repair and mutagenesis; Discussion
Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research; Discussion; Discussion; Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects; Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins; Discussion; General Discussion I; Regulation of human drug metabolism by dietary factors; Discussion; Influence of foreign compounds on formation and disposition of reactive metabolites; Discussion Pharmacokinetic factors governing the steady-state concentrations of foreign chemicals and their metabolites; Discussion; Toxicological implications of polymorphic drug metabolism; Immunologically mediated toxicity; Discussion; Toxicological significance of liver hypertrophy produced by inducers of drug-metabolizing enzymes; Discussion; Discussion; Discussion; The influence of nutrition and inducers on mechanisms of toxicity in humans and animals; Influence of environmental chemicals on drug therapy in humans: studies with contraceptivesteroids; Discussion; General Discussion II Vitamin D metabolism in patients treated with phenytoin and phenobarbitone; Discussion; Chemical disease in humans: problems in comparative toxicology; Discussion; Implications for future studies in humans; Final General Discussion; Index of Contributors; Subject Index |
| Record Nr. | UNISA-996206963503316 |
| Amsterdam ; ; New York : , : Excerpta Medica | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Environmental chemicals, enzyme function, and human disease
| Environmental chemicals, enzyme function, and human disease |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica |
| Descrizione fisica | 1 online resource (392 pages) |
| Disciplina | 615.9 |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Toxicology
Drugs - Metabolism Enzyme induction Biotransformation (Metabolism) |
| ISBN |
1-280-78392-3
9786613694317 0-470-72059-X 0-470-71827-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Environmental Chemicals Enzyme Function and Human Disease; Contents; Chairman's introduction; The role of the drug-metabolizing enzymes; Discussion; The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver; Discussion; Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues; Discussion; Induction of enzymes involved in DNA repair and mutagenesis; Discussion
Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research; Discussion; Discussion; Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects; Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins; Discussion; General Discussion I; Regulation of human drug metabolism by dietary factors; Discussion; Influence of foreign compounds on formation and disposition of reactive metabolites; Discussion Pharmacokinetic factors governing the steady-state concentrations of foreign chemicals and their metabolites; Discussion; Toxicological implications of polymorphic drug metabolism; Immunologically mediated toxicity; Discussion; Toxicological significance of liver hypertrophy produced by inducers of drug-metabolizing enzymes; Discussion; Discussion; Discussion; The influence of nutrition and inducers on mechanisms of toxicity in humans and animals; Influence of environmental chemicals on drug therapy in humans: studies with contraceptivesteroids; Discussion; General Discussion II Vitamin D metabolism in patients treated with phenytoin and phenobarbitone; Discussion; Chemical disease in humans: problems in comparative toxicology; Discussion; Implications for future studies in humans; Final General Discussion; Index of Contributors; Subject Index |
| Record Nr. | UNINA-9910144657003321 |
| Amsterdam ; ; New York : , : Excerpta Medica | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Environmental chemicals, enzyme function, and human disease
| Environmental chemicals, enzyme function, and human disease |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Amsterdam ; ; New York : , : Excerpta Medica |
| Descrizione fisica | 1 online resource (392 pages) |
| Disciplina | 615.9 |
| Collana | Ciba Foundation symposium (new series) |
| Soggetto topico |
Toxicology
Drugs - Metabolism Enzyme induction Biotransformation (Metabolism) |
| ISBN |
9786613694317
9781280783920 1280783923 9780470720592 047072059X 9780470718278 0470718277 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Environmental Chemicals Enzyme Function and Human Disease; Contents; Chairman's introduction; The role of the drug-metabolizing enzymes; Discussion; The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver; Discussion; Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues; Discussion; Induction of enzymes involved in DNA repair and mutagenesis; Discussion
Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research; Discussion; Discussion; Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects; Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins; Discussion; General Discussion I; Regulation of human drug metabolism by dietary factors; Discussion; Influence of foreign compounds on formation and disposition of reactive metabolites; Discussion Pharmacokinetic factors governing the steady-state concentrations of foreign chemicals and their metabolites; Discussion; Toxicological implications of polymorphic drug metabolism; Immunologically mediated toxicity; Discussion; Toxicological significance of liver hypertrophy produced by inducers of drug-metabolizing enzymes; Discussion; Discussion; Discussion; The influence of nutrition and inducers on mechanisms of toxicity in humans and animals; Influence of environmental chemicals on drug therapy in humans: studies with contraceptivesteroids; Discussion; General Discussion II Vitamin D metabolism in patients treated with phenytoin and phenobarbitone; Discussion; Chemical disease in humans: problems in comparative toxicology; Discussion; Implications for future studies in humans; Final General Discussion; Index of Contributors; Subject Index |
| Record Nr. | UNINA-9910806163003321 |
| Amsterdam ; ; New York : , : Excerpta Medica | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Enzyme Inhibition and Bioapplications / / edited by Rakesh Sharma
| Enzyme Inhibition and Bioapplications / / edited by Rakesh Sharma |
| Pubbl/distr/stampa | Rijeka, Croatia : , : IntechOpen, , 2012 |
| Descrizione fisica | 1 online resource (332 pages) : illustrations |
| Disciplina | 599.0 |
| Soggetto topico | Enzyme induction |
| ISBN | 953-51-5294-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910317593303321 |
| Rijeka, Croatia : , : IntechOpen, , 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
