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Binary data analysis of randomized clinical trials with noncompliance [[electronic resource] /] / Kung-Jong Lui
| Binary data analysis of randomized clinical trials with noncompliance [[electronic resource] /] / Kung-Jong Lui |
| Autore | Lui Kung-Jong |
| Pubbl/distr/stampa | Chichester, West Sussex, United Kingdom, : John Wiley & Sons Inc., 2011 |
| Descrizione fisica | 1 online resource (332 p.) |
| Disciplina | 615.5072/4 |
| Collana | Statistics in practice |
| Soggetto topico |
Clinical trials - Statistical methods
Drugs - Testing - Statistical methods |
| ISBN |
1-283-40536-9
9786613405364 1-119-99160-9 1-119-99161-7 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Binary Data Analysis of Randomized Clinical Trials with Noncompliance; Contents; Preface; About the Author; 1 Randomized clinical trials with noncompliance: issues, definitions and problems of commonly used analyses; 1.1 Randomized encouragement design (RED); 1.2 Randomized consent designs; 1.2.1 Single-consent randomized design (SCRD); 1.2.2 Double-consent randomized design (DCRD); 1.3 Treatment efficacy versus programmatic effectiveness; 1.4 Definitions of commonly used terms and assumptions; 1.5 Most commonly used analyses for a RCT with noncompliance; Exercises
2 Randomized clinical trials with noncompliance under parallel groups design 2.1 Testing superiority; 2.2 Testing noninferiority; 2.2.1 Using the difference in proportions; 2.2.2 Using the ratio of proportions; 2.2.3 Using the odds ratio of proportions; 2.3 Testing equivalence; 2.3.1 Using the difference in proportions; 2.3.2 Using the ratio of proportions; 2.3.3 Using the odds ratio of proportions; 2.4 Interval estimation; 2.4.1 Estimation of the proportion difference; 2.4.2 Estimation of the proportion ratio; 2.4.3 Estimation of the odds ratio; 2.5 Sample size determination 2.5.1 Sample size calculation for testing superiority 2.5.2 Sample size calculation for testing noninferiority; 2.5.3 Sample size calculation for testing equivalence; 2.6 Risk model-based approach; 2.6.1 Constant risk additive model; 2.6.2 Constant risk multiplicative model; 2.6.3 Generalized risk additive model; 2.6.4 Generalized risk multiplicative model; Exercises; Appendix; 3 Randomized clinical trials with noncompliance in stratified sampling; 3.1 Testing superiority; 3.2 Testing noninferiority; 3.2.1 Using the difference in proportions; 3.2.2 Using the ratio of proportions 3.2.3 Using the odds ratio of proportions 3.3 Testing equivalence; 3.3.1 Using the difference in proportions; 3.3.2 Using the ratio of proportions; 3.3.3 Using the odds ratio of proportions; 3.4 Interval estimation; 3.4.1 Estimation of the proportion difference; 3.4.2 Estimation of the proportion ratio; 3.4.3 Estimation of the odds ratio; 3.5 Test homogeneity of index in large strata; 3.5.1 Testing homogeneity of the proportion difference; 3.5.2 Testing homogeneity of the proportion ratio; 3.5.3 Test homogeneity of the odds ratio; Exercises; Appendix 4 Randomized clinical trials with noncompliance under cluster sampling 4.1 Testing superiority; 4.2 Testing noninferiority; 4.2.1 Using the difference in proportions; 4.2.2 Using the ratio of proportions; 4.2.3 Using the odds ratio of proportions; 4.3 Testing equivalence; 4.3.1 Using the difference in proportions; 4.3.2 Using the ratio of proportions; 4.3.3 Using the odds ratio of proportions; 4.4 Interval estimation; 4.4.1 Estimation of the proportion difference; 4.4.2 Estimation of the proportion ratio; 4.4.3 Estimation of the odds ratio; 4.5 Sample size determination 4.5.1 Sample size calculation for testing superiority |
| Record Nr. | UNINA-9910131022703321 |
Lui Kung-Jong
|
||
| Chichester, West Sussex, United Kingdom, : John Wiley & Sons Inc., 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Binary data analysis of randomized clinical trials with noncompliance / / Kung-Jong Lui
| Binary data analysis of randomized clinical trials with noncompliance / / Kung-Jong Lui |
| Autore | Lui Kung-Jong |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex, United Kingdom, : John Wiley & Sons Inc., 2011 |
| Descrizione fisica | 1 online resource (332 p.) |
| Disciplina | 615.5072/4 |
| Collana | Statistics in practice |
| Soggetto topico |
Clinical trials - Statistical methods
Drugs - Testing - Statistical methods |
| ISBN |
1-283-40536-9
9786613405364 1-119-99160-9 1-119-99161-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Binary Data Analysis of Randomized Clinical Trials with Noncompliance; Contents; Preface; About the Author; 1 Randomized clinical trials with noncompliance: issues, definitions and problems of commonly used analyses; 1.1 Randomized encouragement design (RED); 1.2 Randomized consent designs; 1.2.1 Single-consent randomized design (SCRD); 1.2.2 Double-consent randomized design (DCRD); 1.3 Treatment efficacy versus programmatic effectiveness; 1.4 Definitions of commonly used terms and assumptions; 1.5 Most commonly used analyses for a RCT with noncompliance; Exercises
2 Randomized clinical trials with noncompliance under parallel groups design 2.1 Testing superiority; 2.2 Testing noninferiority; 2.2.1 Using the difference in proportions; 2.2.2 Using the ratio of proportions; 2.2.3 Using the odds ratio of proportions; 2.3 Testing equivalence; 2.3.1 Using the difference in proportions; 2.3.2 Using the ratio of proportions; 2.3.3 Using the odds ratio of proportions; 2.4 Interval estimation; 2.4.1 Estimation of the proportion difference; 2.4.2 Estimation of the proportion ratio; 2.4.3 Estimation of the odds ratio; 2.5 Sample size determination 2.5.1 Sample size calculation for testing superiority 2.5.2 Sample size calculation for testing noninferiority; 2.5.3 Sample size calculation for testing equivalence; 2.6 Risk model-based approach; 2.6.1 Constant risk additive model; 2.6.2 Constant risk multiplicative model; 2.6.3 Generalized risk additive model; 2.6.4 Generalized risk multiplicative model; Exercises; Appendix; 3 Randomized clinical trials with noncompliance in stratified sampling; 3.1 Testing superiority; 3.2 Testing noninferiority; 3.2.1 Using the difference in proportions; 3.2.2 Using the ratio of proportions 3.2.3 Using the odds ratio of proportions 3.3 Testing equivalence; 3.3.1 Using the difference in proportions; 3.3.2 Using the ratio of proportions; 3.3.3 Using the odds ratio of proportions; 3.4 Interval estimation; 3.4.1 Estimation of the proportion difference; 3.4.2 Estimation of the proportion ratio; 3.4.3 Estimation of the odds ratio; 3.5 Test homogeneity of index in large strata; 3.5.1 Testing homogeneity of the proportion difference; 3.5.2 Testing homogeneity of the proportion ratio; 3.5.3 Test homogeneity of the odds ratio; Exercises; Appendix 4 Randomized clinical trials with noncompliance under cluster sampling 4.1 Testing superiority; 4.2 Testing noninferiority; 4.2.1 Using the difference in proportions; 4.2.2 Using the ratio of proportions; 4.2.3 Using the odds ratio of proportions; 4.3 Testing equivalence; 4.3.1 Using the difference in proportions; 4.3.2 Using the ratio of proportions; 4.3.3 Using the odds ratio of proportions; 4.4 Interval estimation; 4.4.1 Estimation of the proportion difference; 4.4.2 Estimation of the proportion ratio; 4.4.3 Estimation of the odds ratio; 4.5 Sample size determination 4.5.1 Sample size calculation for testing superiority |
| Record Nr. | UNINA-9910813859003321 |
|
Lui Kung-Jong
|
||
| Chichester, West Sussex, United Kingdom, : John Wiley & Sons Inc., 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
An introduction to statistics in early phase trials [[electronic resource] /] / Steven Julious, Say-Beng Tan, David Machin
| An introduction to statistics in early phase trials [[electronic resource] /] / Steven Julious, Say-Beng Tan, David Machin |
| Autore | Julious Steven A |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley, 2010 |
| Descrizione fisica | 1 online resource (271 p.) |
| Disciplina |
610.15195
615/.19012 |
| Altri autori (Persone) |
MachinDavid <1939->
TanSay Beng |
| Soggetto topico |
Drugs - Testing - Statistical methods
Clinical trials - Statistical methods |
| ISBN |
1-282-48277-7
9786612482779 0-470-68616-2 0-470-31917-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
An Introduction to Statistics in Early Phase Trials; Contents; Chapter 1 Early phase trials; Chapter 2 Introduction to pharmacokinetics; Chapter 3 Sample size calculations for clinical trials; Chapter 4 Crossover trial basics; Chapter 5 Multi-period crossover trials; Chapter 6 First time into man; Chapter 7 Bayesian and frequentist methods; Chapter 8 First-time-into-new-population studies; Chapter 9 Bioequivalence studies; Chapter 10 Other Phase I trials; Chapter 11 Phase II trials: general issues; Chapter 12 Dose-response studies; Chapter 13 Phase II trials with toxic therapies
Chapter 14 Interpreting and applying early phase trial resultsChapter 15 Go/No-Go criteria; Appendix; References; Index |
| Record Nr. | UNINA-9910139509803321 |
|
Julious Steven A
|
||
| Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
An introduction to statistics in early phase trials / / Steven Julious, Say-Beng Tan, David Machin
| An introduction to statistics in early phase trials / / Steven Julious, Say-Beng Tan, David Machin |
| Autore | Julious Steven A |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley, 2010 |
| Descrizione fisica | 1 online resource (271 p.) |
| Disciplina |
610.15195
615/.19012 |
| Altri autori (Persone) |
MachinDavid <1939->
TanSay Beng |
| Soggetto topico |
Drugs - Testing - Statistical methods
Clinical trials - Statistical methods |
| ISBN |
9786612482779
9781282482777 1282482777 9780470686164 0470686162 9780470319178 0470319178 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
An Introduction to Statistics in Early Phase Trials; Contents; Chapter 1 Early phase trials; Chapter 2 Introduction to pharmacokinetics; Chapter 3 Sample size calculations for clinical trials; Chapter 4 Crossover trial basics; Chapter 5 Multi-period crossover trials; Chapter 6 First time into man; Chapter 7 Bayesian and frequentist methods; Chapter 8 First-time-into-new-population studies; Chapter 9 Bioequivalence studies; Chapter 10 Other Phase I trials; Chapter 11 Phase II trials: general issues; Chapter 12 Dose-response studies; Chapter 13 Phase II trials with toxic therapies
Chapter 14 Interpreting and applying early phase trial resultsChapter 15 Go/No-Go criteria; Appendix; References; Index |
| Record Nr. | UNINA-9910816269003321 |
|
Julious Steven A
|
||
| Chichester, West Sussex ; ; Hoboken, NJ, : John Wiley, 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Journal of biopharmaceutical statistics
| Journal of biopharmaceutical statistics |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, Inc |
| Disciplina | 615 |
| Soggetto topico |
Pharmacy - Statistical methods
Drugs - Testing - Statistical methods Biometry Biopharmaceutics Pharmacokinetics Pharmacology Biomedicine |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1520-5711 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JBS |
| Record Nr. | UNISA-996213341803316 |
| New York, NY, : Marcel Dekker, Inc | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Journal of biopharmaceutical statistics
| Journal of biopharmaceutical statistics |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, Inc |
| Disciplina | 615 |
| Soggetto topico |
Pharmacy - Statistical methods
Drugs - Testing - Statistical methods Biometry Biopharmaceutics Pharmacokinetics Pharmacology Biomedicine |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1520-5711 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | JBS |
| Record Nr. | UNINA-9910154519903321 |
| New York, NY, : Marcel Dekker, Inc | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Multiple testing problems in pharmaceutical statistics / / editors, Alex Dmitrienko, Ajit C. Tamhane, Frank Bretz
| Multiple testing problems in pharmaceutical statistics / / editors, Alex Dmitrienko, Ajit C. Tamhane, Frank Bretz |
| Pubbl/distr/stampa | Boca Raton : , : Chapman & Hall/CRC/Taylor & Francis, , 2010 |
| Descrizione fisica | 1 online resource (323 p.) |
| Disciplina | 615/.1901 |
| Altri autori (Persone) |
DmitrienkoAlex
TamhaneAjit C BretzFrank |
| Collana | Chapman & Hall/CRC biostatistics series |
| Soggetto topico | Drugs - Testing - Statistical methods |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-19186-3
1-282-90323-3 9786612903236 1-58488-985-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; Copyright; Contents; Preface; List of Contributors; Chapter 1: Multiplicity Problems in Clinical Trials: A Regulatory Perspective; Chapter 2: Multiple Testing Methodology; Chapter 3: Multiple Testing in Dose-Response Problems; Chapter 4: Analysis of Multiple Endpoints in Clinical Trials; Chapter 5: Gatekeeping Procedures in Clinical Trials; Chapter 6: Adaptive Designs and Confirmatory Hypothesis Testing; Chapter 7: Design and Analysis of Microarray Experiments for Pharmacogenomics; Bibliography; Index |
| Record Nr. | UNINA-9910459189503321 |
| Boca Raton : , : Chapman & Hall/CRC/Taylor & Francis, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Multiple testing problems in pharmaceutical statistics / / editors, Alex Dmitrienko, Ajit C. Tamhane, Frank Bretz
| Multiple testing problems in pharmaceutical statistics / / editors, Alex Dmitrienko, Ajit C. Tamhane, Frank Bretz |
| Pubbl/distr/stampa | Boca Raton : , : Chapman & Hall/CRC/Taylor & Francis, , 2010 |
| Descrizione fisica | 1 online resource (323 p.) |
| Disciplina | 615/.1901 |
| Altri autori (Persone) |
DmitrienkoAlex
TamhaneAjit C BretzFrank |
| Collana | Chapman & Hall/CRC biostatistics series |
| Soggetto topico | Drugs - Testing - Statistical methods |
| ISBN |
0-429-19186-3
1-282-90323-3 9786612903236 1-58488-985-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Cover; Title; Copyright; Contents; Preface; List of Contributors; Chapter 1: Multiplicity Problems in Clinical Trials: A Regulatory Perspective; Chapter 2: Multiple Testing Methodology; Chapter 3: Multiple Testing in Dose-Response Problems; Chapter 4: Analysis of Multiple Endpoints in Clinical Trials; Chapter 5: Gatekeeping Procedures in Clinical Trials; Chapter 6: Adaptive Designs and Confirmatory Hypothesis Testing; Chapter 7: Design and Analysis of Microarray Experiments for Pharmacogenomics; Bibliography; Index |
| Record Nr. | UNINA-9910785130203321 |
| Boca Raton : , : Chapman & Hall/CRC/Taylor & Francis, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
