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2017 nurse's drug handbook / / Jones & Bartlett Learning
| 2017 nurse's drug handbook / / Jones & Bartlett Learning |
| Edizione | [Sixteenth edition.] |
| Pubbl/distr/stampa | Burlington, MA : , : Jones & Bartlett Learning, , [2017] |
| Descrizione fisica | 1 online resource (4,700 pages) |
| Soggetto topico |
Clinical pharmacology
Nursing Drugs Drugs - Administration Pharmacology |
| ISBN | 1-284-09934-2 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910162941503321 |
| Burlington, MA : , : Jones & Bartlett Learning, , [2017] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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The AAPS journal
| The AAPS journal |
| Pubbl/distr/stampa | Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical Médicaments - Administration - Dispositifs Techniques pharmaceutiques Médicaments - Administration Tecnologia farmacèutica Dispositius d'administració de medicaments Formes farmacèutiques |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. Revistes electròniques. |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1550-7416 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
AAPSJ
American Association of Pharmaceutical Scientists journal |
| Record Nr. | UNISA-996216608703316 |
| Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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The AAPS journal
| The AAPS journal |
| Pubbl/distr/stampa | Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical Médicaments - Administration - Dispositifs Techniques pharmaceutiques Médicaments - Administration Tecnologia farmacèutica Dispositius d'administració de medicaments Formes farmacèutiques |
| Soggetto genere / forma |
Periodical
Fulltext Periodicals. Revistes electròniques. |
| ISSN | 1550-7416 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
AAPSJ
American Association of Pharmaceutical Scientists journal |
| Record Nr. | UNINA-9910143514203321 |
| Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AAPS PharmSci
| AAPS PharmSci |
| Pubbl/distr/stampa | Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. |
| ISSN | 1522-1059 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910135383503321 |
| Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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AAPS PharmSci
| AAPS PharmSci |
| Pubbl/distr/stampa | Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. |
| ISSN | 1522-1059 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996208575503316 |
| Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Advanced drug delivery reviews
| Advanced drug delivery reviews |
| Pubbl/distr/stampa | [Amsterdam?], : Elsevier Science |
| Soggetto topico |
Drugs - Administration
Pharmaceutical Preparations - administration & dosage Médicaments - Administration |
| Soggetto genere / forma | Periodical |
| ISSN | 1872-8294 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996208785303316 |
| [Amsterdam?], : Elsevier Science | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Advanced drug delivery reviews
| Advanced drug delivery reviews |
| Pubbl/distr/stampa | [Amsterdam?], : Elsevier Science |
| Soggetto topico |
Drugs - Administration
Pharmaceutical Preparations - administration & dosage Médicaments - Administration |
| Soggetto genere / forma | Periodical |
| ISSN | 1872-8294 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910146359003321 |
| [Amsterdam?], : Elsevier Science | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Current technologies to increase the transdermal delivery of drugs [[electronic resource] /] / editor, José Juan Escobar-Chávez ; co-editor, Virginia Merino
| Current technologies to increase the transdermal delivery of drugs [[electronic resource] /] / editor, José Juan Escobar-Chávez ; co-editor, Virginia Merino |
| Pubbl/distr/stampa | [S.l.], : Bentham e Books, [2010] |
| Descrizione fisica | 1 online resource (155 p.) |
| Disciplina | 615.67 |
| Altri autori (Persone) |
Escobar-ChávezJosé Juan
MerinoVirginia |
| Soggetto topico |
Transdermal medication
Drugs - Administration |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60805-191-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 eBooks End User License Agreement-Website; 04 Table of Contents; 05 Foreword; 06 Preface; 07 LIST OF CONTRIBUTORS; 08 CHAPTER 1; 09 CHAPTER 2; 10 CHAPTER 3; 11 CHAPTER 4; 12 CHAPTER 5; 13 CHAPTER 6; 14 CHAPTER 7; 15 Glossary; 16 INDEX |
| Record Nr. | UNINA-9910459620803321 |
| [S.l.], : Bentham e Books, [2010] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Current technologies to increase the transdermal delivery of drugs [[electronic resource] /] / editor, José Juan Escobar-Chávez ; co-editor, Virginia Merino
| Current technologies to increase the transdermal delivery of drugs [[electronic resource] /] / editor, José Juan Escobar-Chávez ; co-editor, Virginia Merino |
| Pubbl/distr/stampa | [S.l.], : Bentham e Books, [2010] |
| Descrizione fisica | 1 online resource (155 p.) |
| Disciplina | 615.67 |
| Altri autori (Persone) |
Escobar-ChávezJosé Juan
MerinoVirginia |
| Soggetto topico |
Transdermal medication
Drugs - Administration |
| ISBN | 1-60805-191-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 01 Title.pdf; 02 Cover Page; 03 eBooks End User License Agreement-Website; 04 Table of Contents; 05 Foreword; 06 Preface; 07 LIST OF CONTRIBUTORS; 08 CHAPTER 1; 09 CHAPTER 2; 10 CHAPTER 3; 11 CHAPTER 4; 12 CHAPTER 5; 13 CHAPTER 6; 14 CHAPTER 7; 15 Glossary; 16 INDEX |
| Record Nr. | UNINA-9910785425703321 |
| [S.l.], : Bentham e Books, [2010] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Fundamentals of drug delivery / / Michael S. Roberts [and three others]
| Fundamentals of drug delivery / / Michael S. Roberts [and three others] |
| Pubbl/distr/stampa | Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2021] |
| Descrizione fisica | 1 online resource (579 pages) |
| Disciplina | 615.6 |
| Soggetto topico |
Drugs - Administration
Drug delivery systems |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-119-76967-1
1-119-76964-7 1-119-76965-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title Page -- Copyright -- Contents -- Preface -- List of Contributors -- Part I Product Design, the Essence of Effective Therapeutics -- Chapter 1 Challenges and Innovations of Controlled Drug Delivery -- 1.1 Background -- 1.2 Parenteral Dosage Forms -- 1.2.1 Intravenous Route (IV) -- 1.2.2 Intramuscular Route (IM) -- 1.2.3 Subcutaneous Route (SC) -- 1.2.4 Other Parenteral Routes -- 1.3 Oral Route and Delivery Systems -- 1.4 Nasal Drug Delivery -- 1.5 Pulmonary Drug Delivery -- 1.6 Transdermal Drug Delivery -- 1.7 Ocular Drug Delivery -- 1.8 Drug Delivery System Development Process -- 1.9 Conclusion -- References -- Chapter 2 Challenges in Design of Drug Delivery Systems -- 2.1 Drug Properties to be Considered in Design of Controlled Release Products -- 2.2 Physicochemical Factors that Need to be Considered in Design of CRDDS -- 2.2.1 Dose Size -- 2.2.2 Molecular Weight/Size -- 2.2.3 Aqueous Solubility -- 2.2.4 Lipid Solubility and Partition Coefficient -- 2.2.5 Physicochemical Stability -- 2.3 Biopharmaceutical Properties that Deserve Consideration in Design of Controlled Release Products -- 2.3.1 Biological Half‐life -- 2.3.2 Absorption -- 2.3.3 Metabolism -- 2.3.4 Presystemic Clearance -- 2.3.5 Margin of Safety -- 2.3.6 Adverse Effects -- 2.3.7 Therapeutic Need -- 2.3.8 Role of Circadian Rhythm -- 2.4 Conclusion -- References -- Chapter 3 Drug Delivery of the Future (?) -- 3.1 Introduction -- 3.2 Therapeutic Indicators -- 3.3 Drugs of the Future -- 3.4 Delivering the Drugs of the Future -- 3.5 A View to the Longer Term? -- 3.6 Conclusion -- References -- Chapter 4 The Pharmaceutical Drug Development Process: Selecting a Suitable Drug Candidate -- 4.1 The Oral Drug Candidate: How to Get There and Questions to Answer -- 4.2 Challenges for Selecting a Topical Drug Candidate.
4.3 Percutaneous Flux as a Surrogate Measurement of Skin Tissue Concentration -- 4.4 Learnings from Past Topical Drug Development of Factors Affecting Efficacy -- 4.5 Dermal Pharmacokinetics/Pharmacodynamics -- 4.6 Assessment of Systemic Exposure -- 4.7 Screening Cascade Approach to Select a Dermal Drug Candidate -- 4.7.1 Efficacy (Lack of Target Engagement) -- 4.7.2 Developability -- 4.7.3 Local Safety -- 4.7.4 Systemic Safety -- 4.8 Opportunities for Repurposing Molecules into Dermally Active Treatments for Cosmeceutical or Pharmaceutical Approaches -- 4.9 Conclusion -- References -- Chapter 5 Preformulation and Physicochemical Characterization Underpinning the Development of Controlled Drug Delivery Systems -- 5.1 When Is a Controlled Drug Delivery System Needed? -- 5.2 Optimizing Drug Characteristics -- 5.3 Defining the Product Profile -- 5.4 Preformulation and Physicochemical Characterization Underpinning Development of CDD -- 5.4.1 Feasibility and Risk Assessment -- 5.4.2 Solubility and Dissolution Rate -- 5.4.3 Permeability -- 5.4.4 Drug and Drug Product Particle Sizes -- 5.4.5 Solid‐State Chemistry -- 5.4.5.1 Crystallinity and Polymorphism -- 5.4.5.2 Salts -- 5.4.6 Stability -- 5.4.7 Excipient Compatibility -- 5.4.8 Bulk Powder Properties -- 5.4.9 Drug Metabolism and Pharmacokinetic Modeling -- 5.4.9.1 Guiding the Design of CDD Dosage Forms -- 5.4.9.2 Establishing In Vitro-In Vivo Correlation (IVIVC) -- 5.4.9.3 Physiologically Based Pharmacokinetic (PBPK) Modeling Tools -- 5.5 Conclusion -- References -- Chapter 6 Mathematical Models Describing Kinetics Associated with Controlled Drug Delivery Across Membranes -- 6.1 Introduction -- 6.1.1 General Description -- 6.1.2 Governing Equations -- 6.1.2.1 Differential Equations -- 6.1.2.2 Dimensionless Differential Equations -- 6.1.2.3 Initial and Boundary Conditions -- 6.1.3 Other Derived Quantities. 6.1.4 Dimensionless Variables and Groups -- 6.2 Model Solutions -- 6.2.1 Type A Models - Well‐Stirred Vehicle on One Membrane -- 6.2.1.1 Model A1 -- 6.2.1.2 Model A2 -- 6.2.1.3 Model A3 -- 6.2.1.4 Model A4 -- 6.2.1.5 Model A5 -- 6.2.1.6 Model A6 -- 6.2.1.7 Model A7 -- 6.2.1.8 Model A8 -- 6.2.1.9 Model A9 -- 6.2.1.10 Model A9a -- 6.2.1.11 Model A9b -- 6.2.1.12 Model A10 -- 6.2.1.13 Model A11 -- 6.2.1.14 Model A12 -- 6.2.1.15 Model A13 -- 6.2.2 Type B Models - Unstirred Semi‐infinite Vehicle on One Membrane -- 6.2.2.1 Model B1 -- 6.2.2.2 Model B2 -- 6.2.3 Type C - Well Stirred Vehicle on Two Membranes in Series -- 6.2.3.1 Model C1 -- 6.3 Solution Methods -- 6.3.1 Separation of Variables Solutions -- 6.3.1.1 Separating the Partial Differential Equation of N Independent Variables into N Ordinary Differential Equations -- 6.3.1.2 Choosing the Sign (Positive or Negative) on the Separation Constant -- 6.3.1.3 Finding the Constants of Integration and the Eigenvalues -- 6.3.1.4 Superposition -- 6.3.1.5 Finding the Remaining Constants of Integration -- 6.3.1.6 Guidelines for Using Separation of Variable Methods to Solve Partial Differential Equations -- 6.3.1.7 Methods for Making a Nonhomogeneous Partial Differential Equation or Nonhomogeneous Boundary Conditions Homogeneous -- 6.3.1.8 Choosing the Index Starting Value on the Sum of All Solutions (i.e. should n & -- equals -- 1 or 0?) -- 6.3.2 Laplace Transform Solutions -- 6.3.2.1 Using Laplace Transforms to Determine Lag Times, Steady‐state Values and Other Derived Quantities -- 6.3.2.2 Inversion of Laplace Transformed Functions to Time Domain Functions by Method of Residues -- 6.3.2.3 Example A - Model A1 -- 6.3.2.4 Example B - Model A10 -- 6.3.3 Useful Identities -- References. Chapter 7 Understanding Drug Delivery Outcomes: Progress in Microscopic Modeling of Skin Barrier Property, Permeation Pathway, Dermatopharmacokinetics, and Bioavailability -- 7.1 Introduction -- 7.2 Governing Equation -- 7.2.1 Homogenized Model -- 7.2.2 Microscopic Model -- 7.2.2.1 Solute Diffusion in SC Lipid -- 7.2.2.2 Solute Diffusion in SC Corneocytes -- 7.2.2.3 Solute Diffusion in Appendages -- 7.2.3 Numerical Methods -- 7.3 Input Parameters -- 7.3.1 SC Microstructure -- 7.3.2 SC Lipid-Water Partition -- 7.3.3 Diffusivity in SC Lipids -- 7.3.4 Binding to Keratin -- 7.3.5 Diffusivity in Corneocytes -- 7.3.6 Solute Diffusivity and Partition in Sebum -- 7.4 Application -- 7.4.1 Steady‐State -- 7.4.2 Dermatopharmacokinetics -- 7.4.3 Systemic Pharmacokinetics -- 7.4.4 Shunt Pathway -- 7.5 Perspective -- References -- Chapter 8 Role of Membrane Transporters in Drug Disposition -- 8.1 Introduction -- 8.2 Distribution of Major Drug Transporters in Human Tissues -- 8.2.1 Major Drug Transporters in the Intestine -- 8.2.1.1 Drug Transporters Expressed in the Apical (Luminal) Membrane -- 8.2.1.2 Drug Transporters Expressed in the Basolateral Membrane -- 8.2.1.3 Expression of Drug Transporters in Different Intestinal Regions -- 8.2.2 Major Drug Transporters in the Liver -- 8.2.2.1 Drug Transporters Expressed in the Apical Membrane of Hepatocytes -- 8.2.2.2 Drug Transporters Expressed in the Basolateral (Sinusoidal) Membrane of Hepatocytes -- 8.2.2.3 Drug Transporters Expressed in the Bile Duct Epithelia (Cholangiocytes) -- 8.2.3 Major Drug Transporters in the Kidney -- 8.2.3.1 Drug Transporters Expressed in the Apical Membrane of Proximal Tubule Cells -- 8.2.3.2 Drug Transporters Expressed in the Basolateral Membrane of Proximal Tubule Cells -- 8.2.4 Major Drug Transporters in the Central Nervous System (CNS). 8.2.4.1 Drug Transporters Expressed in the Capillary Endothelial Cells of BBB -- 8.2.4.2 Drug Transporters Expressed in the Choroid Plexus Epithelial Cells of BCSFB -- 8.2.5 Major Drug Transporters in Other Tissues -- 8.2.5.1 Drug Transporters Expressed in Placenta Villi Epithelial Cells (Syncytiotrophoblasts) -- 8.2.5.2 Drug Transporters Expressed in Mammary Glands -- 8.2.5.3 Drug Transporters Expressed in the Blood-Testis‐Barrier (BTB) -- 8.3 Role of Drug Transporters in Drug Disposition -- 8.3.1 Role of P‐gp in Drug Disposition -- 8.3.2 Role of BCRP in Drug Disposition -- 8.3.3 Role of BSEP in Drug‐Induced Cholestatic Liver Injury -- 8.3.4 Role of MRPs (MRP2, MRP3, and MRP4) in Drug Disposition -- 8.3.5 Role of OATPs (OATP1B1, OATP1B3, and OATP2B1) in Drug Disposition -- 8.3.6 Role of OATs (OAT1 and OAT3) in Drug Disposition -- 8.3.7 Role of OCTs (OCT1 and OCT2)/MATEs (MATE1 and MATE2‐K) in Drug Disposition -- 8.4 Closing Remarks -- References -- Part II Challenges in Controlled Drug Delivery and Advanced Delivery Technologies -- Chapter 9 Advanced Drug Delivery Systems for Biologics -- 9.1 Introduction -- 9.2 Considerations in Biologics Product Development -- 9.2.1 Challenges Specific to the Route of Administration -- 9.2.2 Challenges Related to Parenteral Administration -- 9.2.3 Optimization of Dosage Regimens -- 9.3 Administration Routes for Biologics Delivery -- 9.3.1 Parenteral Route -- 9.3.2 Oral Route -- 9.3.3 Buccal Route -- 9.3.4 Sublingual Route -- 9.3.5 Pulmonary Route -- 9.3.5.1 Additional Concerns in Pulmonary Delivery -- 9.3.6 Intranasal Route -- 9.3.7 Trans(dermal) Delivery -- 9.3.7.1 Gene Delivery -- 9.3.7.2 Vaccine Delivery -- 9.3.7.3 Protein Delivery -- 9.3.8 Dermal Delivery of Growth Hormones -- 9.3.9 Vaginal Route -- 9.4 Conclusion -- References. Chapter 10 Recent Advances in Cell‐Mediated Drug Delivery Systems for Nanomedicine and Imaging. |
| Record Nr. | UNINA-9910555076603321 |
| Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Soggetto topico
-
Drugs - Administration
(30)
- Drug delivery systems (6)
- Nursing (6)
- Intravenous therapy (5)
- Drug Therapy (4)