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Journal of receptor and signal transduction research
| Journal of receptor and signal transduction research |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, 1995- |
| Descrizione fisica | 1 online resource |
| Disciplina | 574 |
| Soggetto topico |
Cell receptors
Cellular signal transduction Drug receptors Second messengers (Biochemistry) Receptors, Cell Surface Receptors, Drug Signal Transduction Récepteurs cellulaires Seconds messagers (Biochimie) Transduction du signal cellulaire Récepteurs de médicaments Histology Physiology Receptoren Transductie |
| Soggetto genere / forma | Periodicals. |
| ISSN | 1532-4281 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | Journal of receptors and signal transduction |
| Record Nr. | UNINA-9910154514603321 |
| New York, NY, : Marcel Dekker, 1995- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
| Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1970 |
| Descrizione fisica | 1 online resource (324 p.) |
| Altri autori (Persone) |
PorterRuth
O'ConnorMaeve |
| Collana | Novartis Foundation Symposia |
| Soggetto topico | Drug receptors |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-76839-8
9786613679161 0-470-71976-1 0-470-71741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index |
| Record Nr. | UNINA-9910144668503321 |
| London, : J. & A. Churchill, 1970 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
| Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1970 |
| Descrizione fisica | 1 online resource (324 p.) |
| Altri autori (Persone) |
PorterRuth
O'ConnorMaeve |
| Collana | Novartis Foundation Symposia |
| Soggetto topico | Drug receptors |
| ISBN |
1-280-76839-8
9786613679161 0-470-71976-1 0-470-71741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index |
| Record Nr. | UNINA-9910642847803321 |
| London, : J. & A. Churchill, 1970 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
| Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1970 |
| Descrizione fisica | 1 online resource (324 p.) |
| Altri autori (Persone) |
PorterRuth
O'ConnorMaeve |
| Collana | Novartis Foundation Symposia |
| Soggetto topico | Drug receptors |
| ISBN |
1-280-76839-8
9786613679161 0-470-71976-1 0-470-71741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index |
| Record Nr. | UNISA-996202103403316 |
| London, : J. & A. Churchill, 1970 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
| Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1970 |
| Descrizione fisica | 1 online resource (324 p.) |
| Altri autori (Persone) |
PorterRuth
O'ConnorMaeve |
| Collana | Novartis Foundation Symposia |
| Soggetto topico | Drug receptors |
| ISBN |
1-280-76839-8
9786613679161 0-470-71976-1 0-470-71741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index |
| Record Nr. | UNINA-9910829877803321 |
| London, : J. & A. Churchill, 1970 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular properties of drug receptors : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
| Molecular properties of drug receptors : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor |
| Pubbl/distr/stampa | London, : J. & A. Churchill, 1970 |
| Descrizione fisica | 1 online resource (324 p.) |
| Altri autori (Persone) |
PorterRuth
O'ConnorMaeve |
| Collana | Novartis Foundation Symposia |
| Soggetto topico | Drug receptors |
| ISBN |
1-280-76839-8
9786613679161 0-470-71976-1 0-470-71741-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index |
| Record Nr. | UNINA-9910876829703321 |
| London, : J. & A. Churchill, 1970 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Nuclear receptors as drug targets / / edited by Eckhard Ottow and Hilmar Weinmann
| Nuclear receptors as drug targets / / edited by Eckhard Ottow and Hilmar Weinmann |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2008 |
| Descrizione fisica | 1 online resource (524 p.) |
| Disciplina | 615.7 |
| Altri autori (Persone) |
OttowE <1953-> (Eckhard)
WeinmannHilmar |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Drug receptors
Nuclear receptors (Biochemistry) Drug targeting |
| ISBN |
1-281-94720-2
9786611947200 3-527-62329-9 3-527-62330-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Nuclear Receptors as Drug Targets; Contents; List of Contributors; Preface; A Personal Foreword; 1 Nuclear Receptors as Drug Targets: A Historical Perspective of Modern Drug Discovery; 1.1 Introduction; 1.2 Short Historical Overview on Nuclear Receptors in Pharmacological Research and Drug Discovery; 1.2.1 Glucocorticoid Receptor Research; 1.2.2 Estrogen Receptor Research; 1.2.3 Progesterone Receptor Research; 1.2.4 Other Receptor Research; 1.3 Recent Progress in Nuclear Receptor Drug Discovery; 1.3.1 SERMs; 1.3.2 Selective GR Modulators
1.3.3 Other Modulator Efforts: PR, MR, AR, PPAR, FXR and LXR1.4 Modern Methods and Technologies in Nuclear Receptor Drug Discovery; 1.4.1 Cofactor Interaction Screening; 1.4.2 Microarray Technology and Gene Expression Profiling; 1.4.3 Novel Computational Methods; 1.4.4 Structural Biology; 1.5 Summary and Future Developments; References; 2 Targeting the Nuclear Receptor-Cofactor Interaction; 2.1 Introduction; 2.2 Evaluation of the Nuclear Receptor-Cofactor Interaction as a Drug Target; 2.2.1 Evaluation of the ER-Coactivator Interaction; 2.2.2 Evaluation of the AR-Coactivator Interaction 2.3 Inhibitors of the Nuclear Receptor-Cofactor Interaction2.3.1 Phage Display Peptides; 2.3.2 Nonnatural Cyclic Peptides; 2.3.3 Small Molecules; 2.4 Perspectives; References; 3 Untangling the Estrogen Receptor Web: Tools to Selectively Study Estrogen-Binding Receptors; 3.1 Physiological Roles of Estrogen and the Challenges in Drug Discovery; 3.2 Possibility of Multiple Targets; 3.3 ERα; 3.3.1 Discovery and Characterization; 3.3.2 Expression Patterns and Response to Known Drugs; 3.3.3 Physiological Roles of ERα; 3.4 ERβ; 3.4.1 Discovery and Characterization 3.4.2 Expression Patterns and Response to Known Drugs3.4.3 Possible Physiological Roles of ERβ; 3.5 ERR; 3.5.1 Discovery and Characterization; 3.5.2 Expression Patterns and Response to Known Drugs; 3.5.3 Possible Physiological Roles of ERRs; 3.6 GPR30; 3.6.1 Discovery and Characterization; 3.6.2 Expression Patterns and Response to Known Drugs; 3.6.3 Possible Physiological Roles of GPR30; 3.6.4 Controversies Over GPR30; 3.7 Membrane ERs; 3.8 Integrated Estrogen Signaling; 3.9 Conclusions; References; 4 Subtype-Selective Estrogens; 4.1 Introduction; 4.1.1 Biology of the Estrogen Receptors 4.1.2 Interaction of ERα and ERβ with Ligands4.2 Subtype-Selective ER Ligands; 4.2.1 ERα Agonists; 4.2.1.1 Six-Membered Heterocycles; 4.2.1.2 Five-Membered Heterocycles; 4.2.1.3 Bicyclononene Ring Systems; 4.2.1.4 Steroidal ERα Agonists; 4.2.2 ERβ Agonists; 4.2.2.1 Diaryl-Ethylenes, Imidazoles, Isoxazoles and Thiophenes; 4.2.2.2 Bicyclic 6+6 Ring Systems; 4.2.2.3 Bicyclic [6+5]-Ring Systems; 4.2.2.4 Tricycles; 4.2.2.5 Tetracyclics; 4.2.2.6 Steroidal ERβ-Selective Estrogens; 4.2.2.7 Miscellaneous ERβ Ligands; 4.2.3 ERα-Selective Antagonists; 4.2.3.1 Triphenylethylenes; 4.2.3.2 Benzothiophenes 4.2.3.3 Indoles |
| Record Nr. | UNINA-9910144109203321 |
| Weinheim, : Wiley-VCH, c2008 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
QuaSAR: Quantitative Structure Activity Relationships of analgesics, narcotic antagonists, and hallucinogens / / editors: Gene Barnett, Milan Trsic, Robert E. Willette
| QuaSAR: Quantitative Structure Activity Relationships of analgesics, narcotic antagonists, and hallucinogens / / editors: Gene Barnett, Milan Trsic, Robert E. Willette |
| Pubbl/distr/stampa | Rockville, Maryland : , : Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Research, , 1978 |
| Descrizione fisica | 1 online resource (ix, 487 pages) : illustrations |
| Collana |
NIDA research monograph
DHEW publication |
| Soggetto topico |
Narcotic antagonists - Analysis
Analgesics - United States - Analysis Hallucinogenic drugs - United States - Analysis Drugs - Structure-activity relationships Drug receptors Drug addiction - United States Analgesics - Analysis Hallucinogenic drugs - Analysis |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | QuaSAR |
| Record Nr. | UNINA-9910712086903321 |
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
| Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina | 615.7 |
| Soggetto topico | Drug receptors |
| Soggetto genere / forma | Electronic books. |
| ISBN |
0-429-14730-9
1-4200-5255-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal
Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover |
| Record Nr. | UNINA-9910460856703321 |
| Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
| Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb |
| Edizione | [Third edition.] |
| Pubbl/distr/stampa | Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010 |
| Descrizione fisica | 1 online resource (314 p.) |
| Disciplina | 615.7 |
| Soggetto topico | Drug receptors |
| ISBN |
0-429-14730-9
1-4200-5255-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal
Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover |
| Record Nr. | UNINA-9910797030603321 |
| Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
