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Journal of receptor and signal transduction research
Journal of receptor and signal transduction research
Pubbl/distr/stampa New York, NY, : Marcel Dekker, 1995-
Descrizione fisica 1 online resource
Disciplina 574
Soggetto topico Cell receptors
Cellular signal transduction
Drug receptors
Second messengers (Biochemistry)
Receptors, Cell Surface
Receptors, Drug
Signal Transduction
Récepteurs cellulaires
Seconds messagers (Biochimie)
Transduction du signal cellulaire
Récepteurs de médicaments
Histology
Physiology
Receptoren
Transductie
Soggetto genere / forma Periodicals.
ISSN 1532-4281
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Altri titoli varianti Journal of receptors and signal transduction
Record Nr. UNINA-9910154514603321
New York, NY, : Marcel Dekker, 1995-
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Pubbl/distr/stampa London, : J. & A. Churchill, 1970
Descrizione fisica 1 online resource (324 p.)
Altri autori (Persone) PorterRuth
O'ConnorMaeve
Collana Novartis Foundation Symposia
Soggetto topico Drug receptors
Soggetto genere / forma Electronic books.
ISBN 1-280-76839-8
9786613679161
0-470-71976-1
0-470-71741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index
Record Nr. UNINA-9910144668503321
London, : J. & A. Churchill, 1970
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Pubbl/distr/stampa London, : J. & A. Churchill, 1970
Descrizione fisica 1 online resource (324 p.)
Altri autori (Persone) PorterRuth
O'ConnorMaeve
Collana Novartis Foundation Symposia
Soggetto topico Drug receptors
ISBN 1-280-76839-8
9786613679161
0-470-71976-1
0-470-71741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index
Record Nr. UNINA-9910642847803321
London, : J. & A. Churchill, 1970
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Pubbl/distr/stampa London, : J. & A. Churchill, 1970
Descrizione fisica 1 online resource (324 p.)
Altri autori (Persone) PorterRuth
O'ConnorMaeve
Collana Novartis Foundation Symposia
Soggetto topico Drug receptors
ISBN 1-280-76839-8
9786613679161
0-470-71976-1
0-470-71741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index
Record Nr. UNISA-996202103403316
London, : J. & A. Churchill, 1970
Materiale a stampa
Lo trovi qui: Univ. di Salerno
Opac: Controlla la disponibilità qui
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Molecular properties of drug receptors [[electronic resource] ] : a Ciba Foundation symposium / / edited by Ruth Porter and Maeve O'Connor
Pubbl/distr/stampa London, : J. & A. Churchill, 1970
Descrizione fisica 1 online resource (324 p.)
Altri autori (Persone) PorterRuth
O'ConnorMaeve
Collana Novartis Foundation Symposia
Soggetto topico Drug receptors
ISBN 1-280-76839-8
9786613679161
0-470-71976-1
0-470-71741-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto MOLECULAR PROPERTIES OF DRUG RECEPTORS; Contents; Chairman's opening remarks; Receptors as defined by their pharmacological properties; Discussion; The cholinergic receptor in skeletal muscle; Discussion; Adenyl cyclase as a component of the adrenergic receptor; Discussion; On receptors in the postsynaptic membrane of the motor end plate; Discussion; General Discussion; Crystallographic studies of the active site of lysozyme; Discussion; Nuclear magnetic resonance studies of protein binding sites: the complex of staphylococcal nuclease with 3'.5'-thymidine diphosphate; Discussion
Fluorescent probes of biological macromoleculesDiscussion; General Discussion; The interaction of the subunits of haemoglobin as a mechanism of control; Discussion; Conformational transitions in the course of membrane excitation; Discussion; General Discussion; Affinity labelling of protein active sites; Discussion; Counting acetylcholine receptors in the electroplax; Discussion; The nature of complex formation; Discussion; Final Discussion; Author index; Subject index
Record Nr. UNINA-9910829877803321
London, : J. & A. Churchill, 1970
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Nuclear receptors as drug targets / / edited by Eckhard Ottow and Hilmar Weinmann
Nuclear receptors as drug targets / / edited by Eckhard Ottow and Hilmar Weinmann
Pubbl/distr/stampa Weinheim, : Wiley-VCH, c2008
Descrizione fisica 1 online resource (524 p.)
Disciplina 615.7
Altri autori (Persone) OttowE <1953-> (Eckhard)
WeinmannHilmar
Collana Methods and principles in medicinal chemistry
Soggetto topico Drug receptors
Nuclear receptors (Biochemistry)
Drug targeting
ISBN 1-281-94720-2
9786611947200
3-527-62329-9
3-527-62330-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Nuclear Receptors as Drug Targets; Contents; List of Contributors; Preface; A Personal Foreword; 1 Nuclear Receptors as Drug Targets: A Historical Perspective of Modern Drug Discovery; 1.1 Introduction; 1.2 Short Historical Overview on Nuclear Receptors in Pharmacological Research and Drug Discovery; 1.2.1 Glucocorticoid Receptor Research; 1.2.2 Estrogen Receptor Research; 1.2.3 Progesterone Receptor Research; 1.2.4 Other Receptor Research; 1.3 Recent Progress in Nuclear Receptor Drug Discovery; 1.3.1 SERMs; 1.3.2 Selective GR Modulators
1.3.3 Other Modulator Efforts: PR, MR, AR, PPAR, FXR and LXR1.4 Modern Methods and Technologies in Nuclear Receptor Drug Discovery; 1.4.1 Cofactor Interaction Screening; 1.4.2 Microarray Technology and Gene Expression Profiling; 1.4.3 Novel Computational Methods; 1.4.4 Structural Biology; 1.5 Summary and Future Developments; References; 2 Targeting the Nuclear Receptor-Cofactor Interaction; 2.1 Introduction; 2.2 Evaluation of the Nuclear Receptor-Cofactor Interaction as a Drug Target; 2.2.1 Evaluation of the ER-Coactivator Interaction; 2.2.2 Evaluation of the AR-Coactivator Interaction
2.3 Inhibitors of the Nuclear Receptor-Cofactor Interaction2.3.1 Phage Display Peptides; 2.3.2 Nonnatural Cyclic Peptides; 2.3.3 Small Molecules; 2.4 Perspectives; References; 3 Untangling the Estrogen Receptor Web: Tools to Selectively Study Estrogen-Binding Receptors; 3.1 Physiological Roles of Estrogen and the Challenges in Drug Discovery; 3.2 Possibility of Multiple Targets; 3.3 ERα; 3.3.1 Discovery and Characterization; 3.3.2 Expression Patterns and Response to Known Drugs; 3.3.3 Physiological Roles of ERα; 3.4 ERβ; 3.4.1 Discovery and Characterization
3.4.2 Expression Patterns and Response to Known Drugs3.4.3 Possible Physiological Roles of ERβ; 3.5 ERR; 3.5.1 Discovery and Characterization; 3.5.2 Expression Patterns and Response to Known Drugs; 3.5.3 Possible Physiological Roles of ERRs; 3.6 GPR30; 3.6.1 Discovery and Characterization; 3.6.2 Expression Patterns and Response to Known Drugs; 3.6.3 Possible Physiological Roles of GPR30; 3.6.4 Controversies Over GPR30; 3.7 Membrane ERs; 3.8 Integrated Estrogen Signaling; 3.9 Conclusions; References; 4 Subtype-Selective Estrogens; 4.1 Introduction; 4.1.1 Biology of the Estrogen Receptors
4.1.2 Interaction of ERα and ERβ with Ligands4.2 Subtype-Selective ER Ligands; 4.2.1 ERα Agonists; 4.2.1.1 Six-Membered Heterocycles; 4.2.1.2 Five-Membered Heterocycles; 4.2.1.3 Bicyclononene Ring Systems; 4.2.1.4 Steroidal ERα Agonists; 4.2.2 ERβ Agonists; 4.2.2.1 Diaryl-Ethylenes, Imidazoles, Isoxazoles and Thiophenes; 4.2.2.2 Bicyclic 6+6 Ring Systems; 4.2.2.3 Bicyclic [6+5]-Ring Systems; 4.2.2.4 Tricycles; 4.2.2.5 Tetracyclics; 4.2.2.6 Steroidal ERβ-Selective Estrogens; 4.2.2.7 Miscellaneous ERβ Ligands; 4.2.3 ERα-Selective Antagonists; 4.2.3.1 Triphenylethylenes; 4.2.3.2 Benzothiophenes
4.2.3.3 Indoles
Record Nr. UNINA-9910144109203321
Weinheim, : Wiley-VCH, c2008
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
QuaSAR: Quantitative Structure Activity Relationships of analgesics, narcotic antagonists, and hallucinogens / / editors: Gene Barnett, Milan Trsic, Robert E. Willette
QuaSAR: Quantitative Structure Activity Relationships of analgesics, narcotic antagonists, and hallucinogens / / editors: Gene Barnett, Milan Trsic, Robert E. Willette
Pubbl/distr/stampa Rockville, Maryland : , : Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Research, , 1978
Descrizione fisica 1 online resource (ix, 487 pages) : illustrations
Collana NIDA research monograph
DHEW publication
Soggetto topico Narcotic antagonists - Analysis
Analgesics - United States - Analysis
Hallucinogenic drugs - United States - Analysis
Drugs - Structure-activity relationships
Drug receptors
Drug addiction - United States
Analgesics - Analysis
Hallucinogenic drugs - Analysis
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti QuaSAR
Record Nr. UNINA-9910712086903321
Rockville, Maryland : , : Department of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse, Division of Research, , 1978
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Edizione [Third edition.]
Pubbl/distr/stampa Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Descrizione fisica 1 online resource (314 p.)
Disciplina 615.7
Soggetto topico Drug receptors
Soggetto genere / forma Electronic books.
ISBN 0-429-14730-9
1-4200-5255-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal
Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover
Record Nr. UNINA-9910460856703321
Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Edizione [Third edition.]
Pubbl/distr/stampa Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Descrizione fisica 1 online resource (314 p.)
Disciplina 615.7
Soggetto topico Drug receptors
ISBN 0-429-14730-9
1-4200-5255-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal
Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover
Record Nr. UNINA-9910797030603321
Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Textbook of receptor pharmacology / / edited by John C. Foreman, Torben Johansen and Alasdair J. Gibb
Edizione [Third edition.]
Pubbl/distr/stampa Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Descrizione fisica 1 online resource (314 p.)
Disciplina 615.7
Soggetto topico Drug receptors
ISBN 0-429-14730-9
1-4200-5255-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Front cover; Contents; Preface; Editors; Contributors; Section I: Drug-Receptor Interactions; Chapter 1. Classical Approaches to the Study of Drug- Receptor Interactions; Section II: Molecular Structure of Receptors; Chapter 2. Structure and Function of 7-TM G-Protein Coupled Receptors; Chapter 3. The Structure of Ligand-Gated Ion Channels; Chapter 4. Molecular Structure of Receptor Tyrosine Kinases; Section III: Ligand-Binding Studies of Receptors; Chapter 5. Direct Measurement of Drug Binding to Receptors; Section IV: Transduction of the Receptor Signal
Chapter 6. Receptors Linked to Ion Channels: Mechanisms of Activation and BlockChapter 7. G-Proteins; Chapter 8. Signal Transduction through Protein Tyrosine Kinases; Section V: Receptors as Pharmaceutical Targets; Chapter 9. Receptors as Pharmaceutical Targets; Index; Back cover
Record Nr. UNINA-9910828389003321
Boca Raton, FL : , : CRC Press, an imprint of Taylor and Francis, , 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui