10th International Conference on the Development of Biomedical Engineering in Vietnam : Proceedings of BME 10, July 25-27, 2024, Phan Thiet, Vietnam: Healthcare Evolution Towards 5P Medicine in Low- and Middle-Income Countries Ecosystem - Volume 2: Tissue Engineering, Drug Discovery, and Health Informatics / / edited by Van Toi Vo, Thi-Hiep Nguyen, Binh Long Vong, Thi Thu Hien Pham, Ngoc Hoan Doan
| 10th International Conference on the Development of Biomedical Engineering in Vietnam : Proceedings of BME 10, July 25-27, 2024, Phan Thiet, Vietnam: Healthcare Evolution Towards 5P Medicine in Low- and Middle-Income Countries Ecosystem - Volume 2: Tissue Engineering, Drug Discovery, and Health Informatics / / edited by Van Toi Vo, Thi-Hiep Nguyen, Binh Long Vong, Thi Thu Hien Pham, Ngoc Hoan Doan |
| Autore | Vo Van Toi |
| Edizione | [1st ed. 2025.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 |
| Descrizione fisica | 1 online resource (1729 pages) |
| Disciplina | 620.5 |
| Altri autori (Persone) |
NguyễnThị Hiệp
LongVong Binh PhamThi Thu Hien DoanNgoc Hoan |
| Collana | IFMBE Proceedings |
| Soggetto topico |
Nanotechnology
Medical informatics Drug delivery systems Nanoengineering Health Informatics Drug Delivery |
| ISBN | 3-031-90197-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Investigation of Hydrogel-Based 3D Model on The Progression of Multicellular Breast Tumor Spheroids -- Fabrication of 3D printed structures based on Carboxymethyl Chitosan and Oxidized Polysaccharide Bio-inks -- A Review of Self-crosslinking Natural Polymeric Hydrogels as Promising Bioinks for Extrusion-based 3D Bioprinting in Cartilage Engineering -- Investigation of 3D-printed Scaffold Properties under CaCl2 Post-crosslinking. |
| Record Nr. | UNINA-9911009335203321 |
Vo Van Toi
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| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025 | ||
| Lo trovi qui: Univ. Federico II | ||
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3D Printing of Pharmaceutical and Drug Delivery Devices : Progress from Bench to Bedside
| 3D Printing of Pharmaceutical and Drug Delivery Devices : Progress from Bench to Bedside |
| Autore | Lamprou Dimitrios A. |
| Edizione | [First eddition.] |
| Pubbl/distr/stampa | Newark : , : John Wiley & Sons, Incorporated, , 2024 |
| Descrizione fisica | 1 online resource (265 pages) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
DouroumisDennis
QiSheng |
| Collana | Advances in Pharmaceutical Technology Series |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology |
| ISBN |
9781119836001
111983600X 9781119835981 1119835984 9781119835998 1119835992 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- 3D Printing of Pharmaceutical and Drug Delivery Devices -- Contents -- About the Editors -- List of Contributors -- Series Preface -- Preface -- 1 Materials for 3D Printing -- 1.1 Introduction -- 1.2 Material Processability Considerations for Pharmaceutical 3DP -- 1.2.1 Thermal Extrusion-Based 3D Printing -- 1.2.1.1 Thermal Considerations -- 1.2.1.2 Solubility Enhancement -- 1.2.1.3 Mechanical Considerations -- 1.2.2 Semi-Solid Extrusion 3DP -- 1.2.2.1 Rheological Considerations -- 1.2.2.2 Example Applications -- 1.2.3 Powder Bed Fusion 3D Printing -- 1.2.3.1 Powder Flowability Considerations -- 1.2.3.2 Powder Packing Density Considerations -- 1.2.3.3 Powder Energy Absorbance Considerations -- 1.2.4 Stereolithography 3D Printing -- 1.3 Classification of Common Materials Used in Pharmaceutical 3DP -- 1.3.1 Alcohol Derived Polymers -- 1.3.2 Eudragits -- 1.3.3 Other Polymers -- 1.3.4 Graft Polymers -- 1.3.5 Photocrosslinkable -- 1.3.6 Natural Materials -- 1.3.7 Lipid Materials -- 1.4 Conclusions and Future Perspectives -- References -- 2 The Use of Microstructure Design and 3D Printing for Tailored Drug Release -- 2.1 Introduction -- 2.2 3D-Printing Technologies -- 2.3 3D Design for Drug-Loaded Device -- 2.3.1 CAD Design-Based Design -- 2.3.2 Computational Software-Based Design -- 2.3.3 3D-Printing Parameter-Based Design -- 2.3.4 Polypills and Complex Designs -- 2.4 3D Designs Influence Drug Release -- 2.4.1 Controlling Drug Release -- 2.4.2 Modifying Drug Release -- 2.5 Challenges and Perspective -- References -- 3 3D Printing of Oral Solid Dosage Forms Using Selective Laser Sintering -- 3.1 Introduction -- 3.2 Operational Principles of Selective Laser Sintering -- 3.2.1 Manufacturing Challenges for SLS -- 3.2.2 Laser Selection and Scanning Speed -- 3.2.3 Powder Material Parameters -- 3.2.4 Powder Bed and Recoater Parameters.
3.3 3D-Printed Oral Dosages -- 3.4 Advantages of SLS -- 3.4.1 Printing Features -- 3.4.2 Control of Surface Properties -- 3.4.3 Printing of Complex Geometries -- 3.4.4 Using a Wide Range of Materials -- 3.4.5 Drug Loading and Dose Combinations -- 3.4.6 Personalised Dosage Forms -- 3.4.7 SLS Disadvantages -- 3.5 Conclusions -- References -- 4 3D Printing for Medical Device Applications -- 4.1 Introduction -- 4.2 3D Printers -- 4.2.1 SLA -- 4.2.2 FFF -- 4.2.3 Selective Laser Sintering (SLS) -- 4.3 Biomaterials for 3D-Printed Medical Devices -- 4.3.1 Bioresorbable Polymers -- 4.3.1.1 Synthetic Bioresorbable Polymers -- 4.3.1.2 Natural Bioresorbable Polymers -- 4.3.2 Non-Bioresorbable Polymers -- 4.3.3 Smart Polymers -- 4.3.4 Metal and Ceramic -- 4.4 3D-Printed Personalised Medical Devices -- 4.4.1 Vascular Repair Devices -- 4.4.2 Splints -- 4.4.3 Nerve Guidance Conduits -- 4.4.4 Tissue Engineering -- 4.4.5 3D Printing in Dentistry -- 4.4.6 3D-Printed Orthopaedic Devices -- 4.5 Regulatory -- 4.6 Future Perspectives -- References -- 5 3D Printed Implants for Long-Acting Drug Delivery -- 5.1 Introduction -- 5.2 Types of 3D-Printed Scaffolds -- 5.2.1 Implantable Scaffolds -- 5.2.1.1 Passive Implants -- 5.2.1.2 Active Implants -- 5.2.2 Injectable Scaffolds -- 5.2.3 Innovative 3D-Printed Scaffolds -- 5.3 Critical Parameters in Designing 3D-Printed Implantable Scaffolds -- 5.3.1 Structural Characteristics -- 5.3.1.1 Geometry of Implants -- 5.3.1.2 Porosity Properties and Pore Features -- 5.3.1.3 Surface Properties -- 5.3.2 Mechanical Properties -- 5.3.3 Biological and Physiological Parameters -- 5.3.3.1 Cellular Adhesion -- 5.3.3.2 Absorption and Degradation Rates -- 5.3.3.3 Biocompatibility Aspects -- 5.4 Critical Parameters in Selecting Materials for 3D-Printed Scaffolds -- 5.4.1 Materials Used in 3D-Printed Long-Acting Scaffolds -- 5.4.1.1 Natural Polymers. 5.4.1.2 Synthetic Polymers -- 5.4.1.3 Ceramics and Metals -- 5.4.1.4 Composites -- References -- 5.5 Manufacturing Techniques for Implantable Scaffolds -- 5.5.1 Hot-Melt Extrusion -- 5.5.2 Compression -- 5.5.3 Injection Moulding -- 5.5.4 Solvent Casting -- 5.5.5 3D Printing -- 5.5.6 Scale-Up in 3D-Printing Process for the Manufacturing of Scaffolds -- 5.6 Drug Release Mechanism of Long-Acting 3D-Printing Polymeric Implantable Systems -- 5.7 Outlining Regulatory Framework for 3D-Printed Implantable Scaffolds -- 5.7.1 Commercial Implantable Scaffolds -- 5.8 Conclusions -- References -- 6 Wound Dressings by 3D Printing -- 6.1 Wound Healing Process -- 6.1.1 Haemostasis/Coagulation -- 6.1.2 Inflammation -- 6.1.3 Proliferation -- 6.1.4 Re-epithelisation/Remodelling -- 6.1.5 Wound Classification -- 6.1.6 Wound Dressings -- 6.1.7 3D Printing -- 6.1.8 3D-Printed Dressings -- 6.2 Case Studies -- 6.3 Summary/Conclusions -- References -- 7 3D Printing of Hydrogels -- 7.1 Introduction -- 7.2 Applications of 3D-Printed Hydrogels -- 7.2.1 Tissue Engineering -- 7.2.2 Wound Healing -- 7.2.3 Drug Delivery -- 7.3 Types of Hydrogel Materials for 3D Printing -- 7.3.1 Natural Polymers -- 7.3.2 Synthetic Polymers -- 7.3.3 Natural-Synthetic Hybrid Polymers -- 7.3.4 Ionically Charged Polymers -- 7.3.5 Crosslinked Polymers -- 7.3.6 Method of Hydrogel Preparation -- 7.4 3D Printing Techniques for Hydrogels -- 7.4.1 Laser-Based 3D Printing -- 7.4.1.1 Stereolithography -- 7.4.1.2 Two-Photon Polymerisation -- 7.4.1.3 Laser-Induced Forward Transfer -- 7.4.2 Extrusion-Based Printing -- 7.4.3 Inkjet-Based Printing -- 7.5 Printability and Printing Parameters -- 7.5.1 Bioink Design -- 7.5.1.1 Materials Selection, Concentration and Viscosity -- 7.5.1.2 Rheological Properties -- 7.5.1.3 Shear-Thinning -- 7.5.1.4 Viscoelasticity and Yield Stress -- 7.5.1.5 Cell Encapsulation. 7.5.2 Crosslinking Techniques -- 7.5.2.1 Thermal Crosslinking -- 7.5.2.2 Physical Ionic Crosslinking -- 7.5.2.3 Chemical Crosslinking -- 7.5.2.4 Photocrosslinking -- 7.5.3 3D Printing Parameters -- 7.5.3.1 Temperature -- 7.5.3.2 Pressure -- 7.5.3.3 Speed -- 7.6 Clinical Translation -- 7.6.1 Regulatory Considerations -- 7.6.2 Manufacturing Considerations -- 7.6.3 Limitations and Future Direction -- 7.7 Conclusions -- References -- 8 Analytical Characterisation of 3D-Printed Medicines -- 8.1 Introduction -- 8.2 Preformulation -- 8.2.1 Thermal Analysis -- 8.2.2 X-Ray Powder Diffraction (XRPD) -- 8.2.3 Infrared Spectroscopy -- 8.2.4 Hot-Stage Microscopy (HSM) -- 8.2.5 Customizsd Sample Preparation for the Preformulation Protocol -- 8.3 In-Process Characterisations -- 8.3.1 Mechanical Analysis -- 8.3.2 Rheological Analysis -- 8.3.3 Drug Characterisation -- 8.4 Final Product -- 8.4.1 Morphological Analysis -- 8.4.2 X-Ray Computed Microtomography (XμCT) -- 8.4.3 Terahertz Pulsed Imaging (TPI) -- 8.4.4 Mercury Porosimetry -- 8.4.5 Helium Pycnometry -- 8.5 Conclusions -- References -- 9 Adoption of 3D Printing in Pharmaceutical Industry -- 9.1 Partnering and Growing -- 9.2 Regulatory Strategy -- 9.2.1 Product Development -- 9.2.2 Manufacturing -- 9.3 Business Model -- 9.3.1 In-House Pipeline Products -- 9.3.2 Co-Development -- 9.4 Regulatory Strategy -- 9.5 Partnering and Growing -- 9.6 Business Model and Strategy -- 9.6.1 Closing Remarks -- References -- 10 Clinical Benefits of 3D Printing in Healthcare -- 10.1 Introduction -- 10.2 3D Printing Technologies -- 10.2.1 Binder Jetting -- 10.2.2 Vat Photopolymerization -- 10.2.3 Powder Bed Fusion -- 10.2.4 Material Jetting -- 10.2.5 Material Extrusion -- 10.2.5.1 Fused Deposition Modelling -- 10.2.5.2 Semi-Solid Extrusion -- 10.2.5.3 Direct Powder Extrusion -- 10.3 Preclinical Applications of 3D Printing. 10.3.1 Immediate and Modified Release Oral Printlets -- 10.3.2 3D-Printed Drug Delivery Devices for Other Routes of Administration -- 10.4 Clinical Applications of 3D Printing -- 10.4.1 Personalised Medications -- 10.4.2 Improved Acceptability and Medication Compliance -- 10.4.2.1 Paediatric Patients -- 10.4.2.2 Adult and Geriatric Patients -- 10.4.3 Mass Manufacturing -- 10.4.4 Decentralised On-Demand Fabrication -- 10.4.5 Veterinary Applications -- 10.5 Challenges, Regulatory View and Future Applications -- 10.6 Conclusion -- References -- 11 Regulatory Aspects of 3D-Printed Medicinal Products -- 11.1 Introduction -- 11.2 Current Regulatory Framework -- 11.3 Quality Aspects of 3D-Printed Medicinal Products -- 11.4 3D-Printed Paediatric Medicinal Products -- 11.5 3D-Printed Systems With Tailored Release Profiles -- 11.6 Conclusions -- Disclaimer -- References -- Index -- EULA. |
| Record Nr. | UNINA-9910876527503321 |
Lamprou Dimitrios A.
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| Newark : , : John Wiley & Sons, Incorporated, , 2024 | ||
| Lo trovi qui: Univ. Federico II | ||
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A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems / Deepak Kaushik, Ravinder Verma
| A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems / Deepak Kaushik, Ravinder Verma |
| Autore | Kaushik Deepak |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Singapore : , : Bentham Science Publishers, , 2021 |
| Descrizione fisica | 1 online resource (211 pages) |
| Disciplina | 615.6 |
| Altri autori (Persone) | VermaRavinder |
| Soggetto topico |
Drug delivery systems
Excipients |
| ISBN |
9789814998000
9814998001 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Title -- Copyright -- End User License Agreement -- Contents -- Foreword -- Preface -- List of Contributors -- Different Methodologies for Improving Solubility and Bioavailability -- Ravinder Verma1, Deepak Kaushik1,*, Ritu Kaushik1 and Vandana Singh1 -- INTRODUCTION -- DIFFICULTIES IN THE ORAL DRUG DELIVERY -- ORAL BIOAVAILABILITY -- REASON FOR POOR ORAL BIOAVAILABILITY -- DRUG SOLUBILITY -- REQUIREMENT FOR SOLUBILITY IMPROVEMENT -- APPROACHES TO ENHANCE ORAL BIOAVAILABILITY -- VARIOUS TECHNIQUES FOR IMPROVING BIOAVAILABILITY -- Salt Formation -- Cyclodextrins Based Complexes -- TECHNIQUES OF COMPLEXATION -- Kneading Technique -- Co-precipitation Technique -- Spray Drying -- NOVEL FORMULATION APPROACHES FOR BIOAVAILABILITY ENHANCEMENT -- Polymeric Micelles -- Liposomes -- Solid Lipid Nanoparticles (SLNs) -- Dendrimers -- PARTICLE SIZE REDUCTION -- Strategies -- Mechanical Micronization -- Jet Milling -- Ball Milling -- High-Pressure Homogenization -- Engineered Particle Size Control -- Strategies of Cryogenic Method -- Cryogenic Method -- Spray Freezing onto Cryogenic Fluids -- Spray Freezing into Cryogenic Liquids -- Spray Freezing into Vapor over Liquid -- Ultra-rapid Freezing (URF) -- Crystal Engineering -- Co-crystals -- Nanoparticles -- Solid Dispersion (SD) -- TECHNIQUES OF SOLID DISPERSION -- Fusion (melt) Technique -- Solvent Technique -- Dropping Technique -- Co-crystal Formation -- Supercritical Fluid Recrystallization (SCF) -- Sonocrystallisation -- Liquisolid Technique -- Formation of Inclusion Complex -- Kneading Method -- Lyophilization/Freeze-Drying Technique -- Microwave Irradiation Method -- Self-micro Emulsifying Drug Delivery Systems (SMEDDS) -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Introduction to Lipid-Based Drug Delivery Systems for Oral Delivery.
Deepak Kaushik1,*, Ravinder Verma1, Rekha Rao2 and Prerna Kaushik1 -- LIPID-BASED DRUG DELIVERY SYSTEM (LBDDS) -- A Perfect Oral Lipid-Based Dosage Forms Must Meet Various Aspects -- Benefits of LBDDS -- LIPID FORMULATION CLASSIFICATION SYSTEM -- Four Types of LFCS -- Classification System for Lipid Formulations -- APPROACHES IN LBDDS -- Emulsion -- Microemulsion -- Nanoemulsion -- Liposomes -- Solid Lipid Nanoparticles -- Niosomes -- Lipospheres -- Ethosomes -- Self-emulsifying Drug Delivery System (SEDDS) -- SMEDDS AND SNEDDS -- Nano Lipid Carriers (NLCs) -- FORMULATION DEVELOPMENT AND CHARACTERIZATION -- Parameters to be Judged for the Development of the Formulation -- GUIDELINES FOR DESIGNING OF LBFS -- FORMULATION FACTORS INFLUENCING BIOAVAILABILITY OF DRUGS FROM LBDDS -- Lipid Digestion -- Mean Droplet Size of Emulsion -- Hydrophobic Nature of API -- Chemism of Lipids -- Ingredient Selection for LBFs -- ANALYSIS OF EXCIPIENTS IN LBDDS -- Chemical Analysis -- Physical Analysis -- Analysis of Physiological Effects of Ingredients -- MECHANISM OF LIPID-BASED DRUG DELIVERY SYSTEM -- MECHANISMS FOLLOWED BY LBDDS FOR UPGRADING THE RETENTION -- Improved Rate of Dissolution/Solubilization -- Extension of Gastric Retention Time -- Stimulation of Lymphatic Transport -- Change in the Physical Barrier Role of GI Tract -- Change in Biochemical Hindrance Capacity of GI Tract -- Impact of Oils on Retention -- Digestion of Lipids -- Retention of Lipids -- Drug Assimilation through the Intestinal Lymphatic System -- THERAPEUTIC EQUIVALENCE OF LBDDS -- CONCLUSION -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Self-Micro Emulsifying Drug Delivery Systems and their Applications -- Deepak Kaushik1,*, Ravinder Verma1 and Parijat Pandey2 -- LIPID-BASED DRUG DELIVERY SYSTEMS -- SELF-MICRO EMULSIFYING DRUG DELIVERY SYSTEM. History of Micro-emulsions -- Benefits -- Drawbacks -- Formulation -- Finding Solubility of the Drug in Various Ingredients -- Selection of Ingredients -- Construction of Ternary Phase Diagram -- Preparation and Evaluation -- Selection of Appropriate Medicament Candidate -- Role of SMEDDS for BCS Class Drugs -- Mechanism of Self-emulsification -- APPLICATIONS OF SMEDDS -- Self-microemulsions in Pharmaceutical -- Cosmetics Agents as Self-microemulsions -- Analytical Purpose of Self-microemulsions -- Self-microemulsions for Biotechnology -- Use of Microemulsions in Enzymatic Reactions -- Microemulsion for Immobilization of Protein -- Bioseparations by Microemulsions -- Microemulsions as Chemical Sensor Materials -- Microemulsions as Microreactors and Blood Substitutes -- DOSAGE FORM OF SMEDDS -- Oral Route -- SE Capsules -- SE Sustained/Controlled Release -- SE Pellets -- SE Solid Dispersions -- Topical Delivery -- Ocular Delivery -- Parental Delivery -- Nasal Delivery -- Drug Targeting -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Components of Self-Microemulsifying Drug Delivery System -- Ravinder Verma1, Deepak Kaushik1,*, Manish Kumar2 and Deepak Parmar3 -- SELECTION OF INGREDIENTS IN SEFS -- Hydrophilic-Lipophilic Balance (HLB) -- Partition Coefficient -- IDENTIFICATION OF SUITABLE DRUG CANDIDATE FOR SEDDS -- COMPONENTS OF SMEDDS -- Lipids/Oils -- Selection of Oil -- Role -- Lipids in Oral Drug delivery -- Methods of Controlled Discharge with Lipids -- Surfactants -- Mechanism -- Classification -- Classification Based on Hydrophilic-Lipophilic Balance (HLB) Number- -- Lipophilic Surfactants -- Hydrophilic Surfactants -- Classification Based on the Composition of Counter-ion- -- Monoatomic/Inorganic -- Polyatomic/Organic -- Role -- Co-surfactants -- Other Components -- Consistency Builder. Enzyme Inhibitors -- IMPACT OF INGREDIENTS ON GLOBULES SIZE -- MULTI-FUNCTIONAL EXCIPIENT USED IN SEDDS/SMEDDS -- Relation of HLB with the Solubility -- Requirement of HLB- Why HLB Required? -- HLB Calculation -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Lymphatic Transport of Lipid-Based Drug Delivery System -- Ravinder Verma1, Deepak Kaushik1,*, Beena Kumari2 and Anurag Khatkar1 -- LYMPHATIC TRANSPORT -- BENEFITS -- Approaches to Upgrade Lymphatic Transportation of the Drug -- Favorable Circumstances of Intestinal Transportation of Drugs -- Parameters Affecting Lymphatic Transportation of LBFs -- Size of Globules -- Charge on Drug -- Molecular Weight of Drug -- Lipophilicity -- Lipid Solubility and Partition Coefficient of Drugs -- Type of Lipid -- Concentration of Surfactant -- VARIOUS MODELS UTILIZED FOR INVESTIGATION OF DRUG TRANSPORTATION VIA LYMPHATIC SYSTEM -- Models for In Vivo -- Models for In Vitro -- Evaluation of Animal Model for Lymphatic Transport -- Lack of Effective In Vitro Tests -- LIMITED LYMPHATIC UPTAKE OF LBDDS -- In Vivo Studies based on Dispersed Formulations for Lymphatic Assimilation -- Impact of Lipidic Excipients on Lymphatic Transport -- Impact Food on Self-emulsification of LBFs -- Reduction of Food Effect -- Biopharmaceutical Issues -- Specificity -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Advantages, Marketed Formulations and Evaluation Parameters of SMEDDS -- Deepak Kaushik1,*, Ravinder Verma1, Vineet Mittal1 and Deepika Purohit2 -- APPLICATIONS OF SMEDDS -- Upgrading Solubility and Bioavailability -- Protection Against Biodegradation -- Low Cost of Production and Ease of Scale-up -- Diminishment of Inter/intra-subject Variability and Food Effects -- Capability to Convey Peptides that are Liable to Enzymatic Hydrolysis in GIT. No Impact of Lipid Digestion Mechanism -- Improved Drug Loading Capacity -- Supersaturable SMEDDS (s-SMEDDS) -- MECHANISM OF SELF-EMULSIFICATION -- FACTORS INFLUENCING SMEDDS -- Nature and Amount of the Drug -- Polarity of the Lipophilic Phase -- Solubility Equailibrium -- Charge on Droplet of Emulsion -- EVALUATION PARAMETERS -- Globule Size Estimation -- Small-angle Neutron Scattering -- Refractive Index and Percent Transmission -- Robustness Dilution -- Zeta Potential Estimation -- Electroconductivity Study -- Turbidimetric Assessment -- Effect of Dilution at various pH -- Impact of Temperature -- Determination of Viscosity -- Cloud Point Estimation -- Centrifugation Stability Evaluation -- Dye Solubilization Test -- TEM Analysis -- Dispersibility Test -- Impact of Drug Loading on Droplet Size -- Drug Content Estimation -- In Vitro Lipolysis -- In Vitro Drug Release Assessment -- Thermodynamic Stability Study -- Permeability Study -- CONSENT FOR PUBLICATION -- CONFLICT OF INTEREST -- ACKNOWLEDGEMENTS -- REFERENCES -- Solid-SMEDDS: Techniques of Solidification and Recent Advancements -- Ravinder Verma1, Deepak Kaushik1, Parijat Pandey2,* and Pawan Jalwal2 -- SOLID SELF-EMULSIFYING DRUG DELIVERY SYSTEM -- Solidification Methods for Altering Semisolid/Liquid Self-emulsifying Drug Delivery System to S-SEDDS -- Spray Drying -- Spray Cooling -- Adsorption to Solid Carriers -- Melt Granulation -- Melt Extrusion/Extrusion Spheronization -- Supercritical Liquid-based Technique -- Issues Related to the Solidification Strategies -- Ways to Deal with the Problems of Solidification Strategies -- Various Advancements of S-SMEDDS -- SE Tablets -- SE Sustained/Controlled-Release Tablets -- SE Capsules -- SE Solid Dispersions -- SE Dry Emulsions -- SE Beads -- Self-emulsifying Pellets (SE pellets) -- SE Sustained-release Microspheres -- SE Nanoparticles. SE Implants. |
| Record Nr. | UNINA-9911117240903321 |
Kaushik Deepak
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| Singapore : , : Bentham Science Publishers, , 2021 | ||
| Lo trovi qui: Univ. Federico II | ||
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The AAPS journal
| The AAPS journal |
| Pubbl/distr/stampa | Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical Médicaments - Administration - Dispositifs Techniques pharmaceutiques Médicaments - Administration Tecnologia farmacèutica Dispositius d'administració de medicaments Formes farmacèutiques |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. Revistes electròniques. |
| Soggetto non controllato | Pharmacy, Therapeutics, & Pharmacology |
| ISSN | 1550-7416 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
AAPSJ
American Association of Pharmaceutical Scientists journal |
| Record Nr. | UNISA-996216608703316 |
| Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
The AAPS journal
| The AAPS journal |
| Pubbl/distr/stampa | Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical Médicaments - Administration - Dispositifs Techniques pharmaceutiques Médicaments - Administration Tecnologia farmacèutica Dispositius d'administració de medicaments Formes farmacèutiques |
| Soggetto genere / forma |
Periodical
Fulltext Periodicals. Revistes electròniques. |
| ISSN | 1550-7416 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
AAPSJ
American Association of Pharmaceutical Scientists journal |
| Record Nr. | UNINA-9910143514203321 |
| Arlington, Va., USA, : American Association of Pharmaceutical Scientists, 2003- | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
AAPS PharmSci
| AAPS PharmSci |
| Pubbl/distr/stampa | Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. |
| ISSN | 1522-1059 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996208575503316 |
| Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
AAPS PharmSci
| AAPS PharmSci |
| Pubbl/distr/stampa | Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 |
| Disciplina | 615 |
| Soggetto topico |
Drug delivery systems
Pharmaceutical technology Drugs - Administration Drugs Chemotherapy Pharmaceutical Preparations Drug Therapy Technology, Pharmaceutical Médicaments - Administration - Dispositifs Techniques pharmaceutiques Médicaments - Administration Systèmes d'administration de médicaments Médicaments Chimiothérapie 44.42 pharmacy, pharmaceuticals |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 1522-1059 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
American Association of Pharmaceutical Scientists PharmSci
PharmSci |
| Record Nr. | UNINA-9910135383503321 |
| Alexandria, VA, : American Association of Pharmaceutical Scientists, [1999?]-2004 | ||
| Lo trovi qui: Univ. Federico II | ||
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Adaptive Dynamic Programming : For Chemotherapy Drug Delivery / / by Jiayue Sun, Shun Xu, Yang Liu, Huaguang Zhang
| Adaptive Dynamic Programming : For Chemotherapy Drug Delivery / / by Jiayue Sun, Shun Xu, Yang Liu, Huaguang Zhang |
| Autore | Sun Jiayue |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (XV, 135 p. 40 illus., 38 illus. in color.) |
| Disciplina | 629.8 |
| Collana | Intelligent Technologies and Robotics Series |
| Soggetto topico |
Automatic control
Robotics Automation Drug delivery systems Control, Robotics, Automation Drug Delivery |
| ISBN | 981-9959-29-2 |
| Classificazione | SCI010000TEC004000 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Acknowledgements -- Chapter1 Introduction -- Chapter 2 Neural Networks-Based Immune Optimization Regulation Using Adaptive Dynamic Programming -- Chapter 3 Optimal Regulation Strategy for Nonzero-Sum Games of the Immune System Using Adaptive Dynamic Programming -- Chapter 4 Evolutionary Dynamics Optimal Research-Oriented Tumor Immunity Architecture -- Chapter 5 N-Level Hierarchy-Based Optimal Control to Develop Therapeutic Strategies for Ecological Evolutionary Dynamics Systems -- Chapter 6 Combination Therapy-Based Adaptive Control for Organism Using Medicine Dosage Regulation Mechanism.-Chapter 7 Adaptive Virotherapy Strategy for Organism with Constrained Input Using Medicine Dosage Regulation Mechanism -- References. |
| Record Nr. | UNINA-9910745587603321 |
Sun Jiayue
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Lo trovi qui: Univ. Federico II | ||
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Additive Manufacturing in Pharmaceuticals / / edited by Subham Banerjee
| Additive Manufacturing in Pharmaceuticals / / edited by Subham Banerjee |
| Autore | Banerjee Subham |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (378 pages) |
| Disciplina | 615.6 |
| Collana | Biomedical and Life Sciences Series |
| Soggetto topico |
Pharmaceutical chemistry
Drug delivery systems Pharmacology Pharmaceutics Drug Delivery Tecnologia farmacèutica Impressió 3D Medicaments |
| Soggetto genere / forma | Llibres electrònics |
| ISBN |
9789819924042
9819924049 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. History and Present Scenario of Additive Manufacturing in Pharmaceuticals -- 2. Fused deposition modeling (FDM) of Pharmaceuticals -- 3. Stereolithography (SLA) in Pharmaceuticals -- 4. Selective Laser Sintering (SLS) In Pharmaceuticals -- 5. Semi-solid Extrusion (SSE) in Pharmaceuticals -- 6. Inkjet and Binder Jet Printing in Pharmaceuticals -- 7. 4D printing: The next dimension of healthcare in cancer research -- 8. 4D Printing in Pharmaceuticals -- 9. Bioprinting in Pharmaceuticals -- 10. Regulatory Perspective of Additive Manufacturing in the Field of Pharmaceuticals -- 11. Machine Learning in Additive Manufacturing of Pharmaceuticals. . |
| Record Nr. | UNINA-9910746101003321 |
Banerjee Subham
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Lo trovi qui: Univ. Federico II | ||
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The ADME Encyclopedia : A Comprehensive Guide on Biopharmacy and Pharmacokinetics / / edited by Alan Talevi
| The ADME Encyclopedia : A Comprehensive Guide on Biopharmacy and Pharmacokinetics / / edited by Alan Talevi |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (1209 pages) |
| Disciplina | 615.7 |
| Collana | Biomedical and Life Sciences Series |
| Soggetto topico |
Pharmacology
Pharmaceutical chemistry Drug delivery systems Pharmaceutics Drug Delivery Farmacocinètica |
| Soggetto genere / forma |
Enciclopèdies electròniques
Llibres electrònics |
| ISBN | 9783030848606 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Drug Dissolution and Drug Release -- Drug Absorption -- Drug Distribution -- Drug Metabolism -- Drug Excretion -- Routes of Administration -- next Generation Drug Delivery Systems -- Pharmacogenomics -- Bioavailability and Bioequivalence -- Biopharmaceutical Drug Products -- Drug-Drug and Food-Drug Interactions -- In vitro and In silico ADME Predictions -- Drug Transporters -- Non-linear Pharmacokinetics -- Time Dependent Pharmacokinetics -- Pharmacometrics and Physiological Models. |
| Record Nr. | UNINA-9910578693903321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Lo trovi qui: Univ. Federico II | ||
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