Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Animal models and experimental medicine
| Animal models and experimental medicine |
| Pubbl/distr/stampa | [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.088 |
| Soggetto topico |
Laboratory animals
Diseases - Animal models Animal models in research Veterinary medicine Laboratory Animal Science Disease Models, Animal Animals, Laboratory Veterinary Medicine Animal Welfare |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2576-2095 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AMEM |
| Record Nr. | UNISA-996291850303316 |
| [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Animal models and experimental medicine
| Animal models and experimental medicine |
| Pubbl/distr/stampa | [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.088 |
| Soggetto topico |
Laboratory animals
Diseases - Animal models Animal models in research Veterinary medicine Laboratory Animal Science Disease Models, Animal Animals, Laboratory Veterinary Medicine Animal Welfare |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2576-2095 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AMEM |
| Record Nr. | UNINA-9910273487903321 |
| [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animal models for the study of human disease [[electronic resource] /] / edited by P. Michael Conn
| Animal models for the study of human disease [[electronic resource] /] / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (1109 p.) |
| Disciplina | 616.0273 |
| Altri autori (Persone) | ConnP. Michael |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| Soggetto genere / forma | Electronic books. |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910459131603321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animal models for the study of human disease / / edited by P. Michael Conn
| Animal models for the study of human disease / / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xviii, 1089 pages) : illustrations (some color) |
| Disciplina | 616.0273 |
| Collana | Gale eBooks |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910792482703321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animal models for the study of human disease / / edited by P. Michael Conn
| Animal models for the study of human disease / / edited by P. Michael Conn |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Elsevier, 2013 |
| Descrizione fisica | 1 online resource (xviii, 1089 pages) : illustrations (some color) |
| Disciplina | 616.0273 |
| Collana | Gale eBooks |
| Soggetto topico |
Diseases - Animal models
Laboratory animals Pathology, Experimental |
| ISBN | 0-12-415912-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; ANIMAL MODELS FOR THE STUDY OF HUMAN DISEASE; Copyright; Contents; Preface; List of Contributors; Part I -ETHICS, RESOURCES AND APPROACHES; Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigator; NATURE AND SCOPE OF THE CHAPTER; THE SUBJECT MATTER OF ANIMAL RESEARCH ETHICS; ASPECTS OF ANIMAL USE AND CARE RELEVANT TO ANIMAL RESEARCH ETHICS; WHY INVESTIGATORS ARE UNIQUELY QUALIFIED TO ENGAGE IN ETHICAL ASSESSMENT OF ANIMAL RESEARCH; WHY INVESTIGATORS SHOULD COMMIT THEMSELVES TO ETHICAL CONDUCT OF ANIMAL RESEARCH
WHY INVESTIGATORS PLAY THE KEY ROLE IN ASSURING THE ETHICAL CONDUCT OF ANIMAL RESEARCH PROJECTS SOURCES OF SUPPORT AND GUIDANCE IN CONDUCTING ETHICAL RESEARCH; DEVELOPING USEFUL ETHICAL GUIDELINES; FUNDAMENTAL PRINCIPLES OF ANIMAL RESEARCH ETHICS; PRACTICAL ETHICAL GUIDELINES FOR INVESTIGATORS; SOME CURRENT DIFFICULT ISSUES IN ANIMAL RESEARCH ETHICS; GENERAL SUGGESTIONS FOR INVESTIGATORS; References; Chapter 2 - Access to Resources: A Model Organism Database for Humans; THE PROBLEM; THE LAMHDI SOLUTION; THE IDEAL SOLUTION; Acknowledgments; References Chapter 3 - The Advent of the Golden Era of Animal Alternatives INTRODUCTION; ANALYTICAL TOOLS FOR THE DETECTION OF FOOD-BORNE DISEASE; AN INVITRO SYSTEM TO ASSESS ADVERSE EFFECTS DURING DEVELOPMENT; DISEASES-IN-A-DISH; NONINVASIVE IMAGING AND RECORDING; CONCLUSIONS; References; Chapter 4 - Environmental Enrichment for Animals Used in Research; INTRODUCTION; APPLIED SCIENCE: ENRICHMENT AS A WELFARE TOOL; BASIC SCIENCE: ENRICHMENT AND ANIMAL MODELS; ENRICHMENT AND EXPERIMENTAL VARIABILITY; ENVIRONMENTAL ENRICHMENT REGULATIONS; IMPLEMENTING AN ENRICHMENT PLAN; CONCLUSIONS; Acknowledgments References Part II -VISION; Chapter 5 - Animal Models of Age-Related Macular Degeneration; INTRODUCTION; COMPARATIVE RETINAL ANATOMY AND THE PATHOLOGY OF AMD; THE GENETICS OF AMD; INFLAMMATION IN AMD; HTRA1 AND LOC387715/ARMS2 IN AMD; OXIDATIVE DAMAGE AND AMD; LIPID METABOLISM AND AMD; SPONTANEOUSLY OCCURRING PRIMATE MODELS OF AMD; MODELING CHOROIDAL NEOVASCULARIZATION IN ADVANCED AMD; CONCLUSION; References; Chapter 6 - N-Methyl-N-Nitrosourea Animal Models for Retinitis Pigmentosa; INTRODUCTION; TIME-COURSE PROGRESSION OF MNU-INDUCED RETINAL DEGENERATION RETINAL DEGENERATION CAUSED BY MNU IN VARIOUS ANIMAL SPECIESAGE-RELATED PHOTORECEPTOR CELL DAMAGE AND SENSITIVITY TO MNU; PHOTORECEPTOR CELL DEATH, CELL DEBRIS REMOVAL, AND RPE CELL MIGRATION; MOLECULAR MECHANISMS IN PHOTORECEPTOR CELL DEATH CAUSED BY MNU; THERAPEUTIC TRIALS AGAINST MNU-INDUCED PHOTORECEPTOR APOPTOSIS; CONCLUDING REMARKS; Acknowledgments; References; Part III -CARDIAC AND CARDIOVASCULAR; Chapter 7 - Animal Models of Myocardial Disease; INTRODUCTION; THE SPECTRUM OF CARDIOVASCULAR DISEASE; CHOICE OF ANIMAL SYSTEM; EXPERIMENTAL DESIGN; ISCHEMIC HEART DISEASE SYSTOLIC HEART FAILURE |
| Record Nr. | UNINA-9910808758703321 |
| London, : Elsevier, 2013 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Animals and the shaping of modern medicine : One Health and its histories / / Abigail Woods, Michael Bresalier, Angela Cassidy, Rachel Mason Dentinger
| Animals and the shaping of modern medicine : One Health and its histories / / Abigail Woods, Michael Bresalier, Angela Cassidy, Rachel Mason Dentinger |
| Autore | Woods Abigail |
| Edizione | [First edition 2018.] |
| Pubbl/distr/stampa | Springer Nature, 2018 |
| Descrizione fisica | 1 online resource (xvii, 280 pages) : illustrations |
| Disciplina | 509 |
| Collana | Medicine and Biomedical Sciences in Modern History |
| Soggetto topico |
Animals - Diseases - History
Diseases - Animal models Medicine - History Veterinary medicine - History |
| ISBN | 3-319-64337-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1: Introduction. Centring animals within medical history -- Chapter 2: Doctors in the Zoo: Connecting human and animal health in British zoological gardens, c1828-1890; Abigail Woods -- Chapter 3: From co-ordinated campaigns to water-tight compartments: Diseased sheep and their investigation in Britain, c1880-1920; Abigail Woods -- Chapter 4: From healthy cows to healthy humans: Integrated approaches to world hunger, c1930-65; Michael Bresalier -- Chapter 5: The Parasitological Pursuit: Crossing species and disciplinary boundaries with Calvin W. Schwabe and the Echinococcus tapeworm, 1956-1975; Rachel Mason Dentinger -- Chapter 6: Humans, other animals and ‘One Health’ in the early twenty-first century; Angela Cassidy -- Chapter 7: Conclusion -- Appendix: Annotated bibliography. |
| Record Nr. | UNINA-9910286407603321 |
Woods Abigail
|
||
| Springer Nature, 2018 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Antimicrobial drug discovery : emerging strategies / / edited by George Tegos and Eleftherios Mylonakis
| Antimicrobial drug discovery : emerging strategies / / edited by George Tegos and Eleftherios Mylonakis |
| Pubbl/distr/stampa | Wallingford, Oxfordshire, U.K., : CABI, 2012 |
| Descrizione fisica | 1 online resource (369 p.) |
| Disciplina | 615.7/92 |
| Altri autori (Persone) |
TegosGeorge
MylonakisEleftherios |
| Collana | Advances in molecular and cellular microbiology |
| Soggetto topico |
Anti-infective agents
Drugs - Design Diseases - Animal models High throughput screening - Methodology Photosensitizing compounds Pharmacology |
| ISBN |
1-283-67084-4
1-78064-031-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Emerging discovery strategies : an evolving necessity / Anthony R. Ball and George P. Tegos -- The antibiotic crisis / Arnold L. Demain and Jaroslav Spizek -- Structure, genetic regulation, physiology and function of the AcrAB-TolC efflux pump of escerichia coli and salmonella / Leonard Amaral ... [et al.] -- Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents / Sanjay M. Jachak ... [et al.] -- Fungal efflux-mediated resistance : from targets to inhibitors / Brian C. Monk ... [et al.] -- Vacuolar ATPase (V-ATPase) : a model proton pump for antifungal drug discovery -- Karlett J Parra -- Drug tolerance, persister cells and drug discovery / Kim Lewis -- Inhibition of quorum sensing as a novel antimicrobial strategy -- Gilles Brackman, Hans J. Nelis and Tom Coenye -- Filamentous temperature-sensitive mutant Z (FtsZ) protein as an antibacterial target / Jaroslaw M. Boberek ... [et al.] -- Lysostaphin : a silver bullet for staph / John F. Kokai-Kun -- Strategies to identify modified ribosomally synthesized antimicrobials -- Alan J. Marsh ... [et al.] -- QSAR based discovery of antimicrobial peptides active against multidrug resistant bacteria / Christopher D. Fjell ... [et al.] -- Acetyl-CoA carboxylase as a target for antibacterial development / Grover L. Waldrop -- Underexploited targets in LPS biogenenesis for the design of antibacterials / Laura Cipolla ... [et al.] -- Predicting and dissecting biomolecular interactions by information-driven docking / Panagiotis Kastritsis & Alexandre M.J.J Bonvin -- Anti-fungals and anti-fungal drug discovery / Richard Calderone ... [et al.] -- Pathosystematic studies and the rational design of antifungal interventions / Elaine M Bignell and Darius Armstrong-James -- In vivo high-throughput antimicrobial discovery screens utilizing caenorhabditis elegans as an alternative host / Jeffrey J. Coleman and Eleftherios Mylonakis -- Drosophila melanogaster as a versatile model for discovery of drugs effective against human microbe-induced infection and pathology / Yiorgos Apidianakis and Dimitrios P. Kontoyiannis -- Antimicrobial photosensitizers - harnessing the power of light to treat infections / Sulbha K Sharma, Tianhong Dai and Michael R Hamblin -- Nanoparticle platforms for antimicrobial therapy / David Trofa, Joshua D. Nosanchuk -- Antimicrobial activity of carbon nanotubes / Shaobin Liu, Yuan Chen. |
| Record Nr. | UNINA-9910626114203321 |
| Wallingford, Oxfordshire, U.K., : CABI, 2012 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910458113103321 |
|
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine [[electronic resource] ] : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910784887003321 |
|
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Comparative physiology, natural animal models, and clinical medicine : insights into clinical medicine from animal adaptations / / Michael A. Singer
| Comparative physiology, natural animal models, and clinical medicine : insights into clinical medicine from animal adaptations / / Michael A. Singer |
| Autore | Singer Michael A (Michael Allan), <1940-> |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | London, : Imperial College Press, c2007 |
| Descrizione fisica | 1 online resource (292 p.) |
| Disciplina |
616.0076
616.0273 |
| Soggetto topico |
Diseases - Animal models
Physiology, Comparative Laboratory animals |
| ISBN |
1-281-86755-1
9786611867553 1-86094-949-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Acknowledgements; Introduction; Chapter 1 Diabetes Mellitus; Introduction; Blood Glucose Values in Birds; Do Birds Suffer Adverse Consequences from a High Blood Glucose Concentration; Anatomic and Physiologic Design Features; Eye; Retinal nutrient supply; Retinal vascularization in mammals; Avian and mammalian retinal physiology and development; Diabetic retinopathy; Kidney; Kidney anatomy and function in birds and mammals; Diabetic nephropathy; (a) Renal glucose transporters; (b) Juxtaglomerular apparatus; Glycated hemoglobin; Concluding Remarks and Future Research; References
Chapter 2 Chronic Renal FailureIntroduction; Metabolic Rate and Renal Function; Nitrogen and Urea Metabolism and Protein Turnover; Nitrogen and urea metabolism; Urea transport proteins; Protein turnover; Alterations in urea and protein metabolism in chronic renal failure; Additional Aspects of Renal Failure; Natural Animal Model; Bear and Small Mammal Hibernators; Concluding Remarks and Future Directions; References; Chapter 3 Atherosclerotic Vascular Disease; Introduction; Atherosclerosis in Mammals; Biology of the Arterial System: Implications for the Genesis of Atherosclerosis in Mammals Genesis of Atherosclerotic LesionsNatural Animal Model: The Fish; Fish Coronary Circulation; Fish Coronary Artery Thickenings; Genesis of Fish Lesions; Biomechanical Factors in Fish; Dietary In.uences and Role of Cholesterol in Fish; Biology of the Vascular Smooth Muscle in Fish; Concluding Remarks: What Can We Learn From the Fish as a Natural Model?; References; Chapter 4 Disuse Osteoporosis and Disuse Muscle Atrophy; Disuse Osteoporosis; Bone biology; Parathyroid hormone (PTH); Vitamin D; Leptin; Mechanical stress; Disuse osteoporosis Natural animal model: American black bear (Ursus americanus)Bone homeostasis in the bear: research questions; Disuse Muscle Atrophy; Maintenance of muscle mass; Protein degradation: mechanisms; Animal models; Studies in humans and small mammal hibernators; Humans; Small mammal hibernators; Natural animal model: the American black bear; The bear: a perspective; References; Chapter 5 Ammonia Toxicity; Ammonia Tolerance and Metabolism; Ammonia tolerance; Ammonia metabolism; Brain Ammonia Metabolism; Glutamatergic Neurons; General considerations (Purves et al., 2004) Glutamate, a Neurotransmitter and the "Glutamate-Glutamine" CycleMechanism of Ammonia Neurotoxicity; Neuropathological effects; Effects on Brain Energy Metabolism; Effects on Glutamatergic Synapses; Ammonia and the Fish Central Nervous System; Role of glutamine; Glutamate; Brain energy metabolism; NMDA receptors; Summary; References; Chapter 6 Hypoxia/Ischemia; Cerebral Blood Flow: Its Regulation; Brain Energy Metabolism; Oxygen and Oxygen/Glucose Deprivation and the Brain; General features of neuronal response; Anoxia tolerant mammalian neurons; Neonatal brain; Dorsal vagal neurons Neonatal neurons |
| Record Nr. | UNINA-9910819948803321 |
|
Singer Michael A (Michael Allan), <1940->
|
||
| London, : Imperial College Press, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
