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Animal models and experimental medicine
| Animal models and experimental medicine |
| Pubbl/distr/stampa | [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.088 |
| Soggetto topico |
Laboratory animals
Diseases - Animal models Animal models in research Veterinary medicine Laboratory Animal Science Disease Models, Animal Animals, Laboratory Veterinary Medicine Animal Welfare |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2576-2095 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AMEM |
| Record Nr. | UNISA-996291850303316 |
| [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Animal models and experimental medicine
| Animal models and experimental medicine |
| Pubbl/distr/stampa | [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- |
| Descrizione fisica | 1 online resource |
| Disciplina | 636.088 |
| Soggetto topico |
Laboratory animals
Diseases - Animal models Animal models in research Veterinary medicine Laboratory Animal Science Disease Models, Animal Animals, Laboratory Veterinary Medicine Animal Welfare |
| Soggetto genere / forma |
Periodical
Fulltext Internet Resources. Periodicals. |
| ISSN | 2576-2095 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti | AMEM |
| Record Nr. | UNINA-9910273487903321 |
| [Hoboken, New Jersey] : , : John Wiley & Sons, Inc., , [2018]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal models for human cancer : discovery and development of novel therapeutics / / edited by Marianne I. Martic-Kehl and P. August Schubiger
| Animal models for human cancer : discovery and development of novel therapeutics / / edited by Marianne I. Martic-Kehl and P. August Schubiger |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2016 |
| Descrizione fisica | 1 online resource (313 p.) |
| Disciplina | 616.994027 |
| Collana | Methods and Principles in Medicinal Chemistry |
| Soggetto topico |
Cancer - Animal models
Disease Models, Animal Neoplasms, Experimental Drug Discovery Animal Experimentation - ethics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
3-527-69591-5
3-527-69588-5 3-527-69589-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910166638803321 |
| Weinheim, Germany : , : Wiley-VCH, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal models for human cancer : discovery and development of novel therapeutics / / edited by Marianne I. Martic-Kehl and P. August Schubiger
| Animal models for human cancer : discovery and development of novel therapeutics / / edited by Marianne I. Martic-Kehl and P. August Schubiger |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Weinheim, Germany : , : Wiley-VCH, , 2016 |
| Descrizione fisica | 1 online resource (313 p.) |
| Disciplina | 616.994027 |
| Collana | Methods and Principles in Medicinal Chemistry |
| Soggetto topico |
Cancer - Animal models
Disease Models, Animal Neoplasms, Experimental Drug Discovery Animal Experimentation - ethics |
| ISBN |
3-527-69591-5
3-527-69588-5 3-527-69589-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910830049203321 |
| Weinheim, Germany : , : Wiley-VCH, , 2016 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal Models for the Study of Human Disease
| Animal Models for the Study of Human Disease |
| Autore | Conn P. Michael |
| Edizione | [2nd ed.] |
| Pubbl/distr/stampa | San Diego : , : Elsevier Science & Technology, , 2017 |
| Descrizione fisica | 1 online resource (1200 pages) |
| Disciplina |
616.027
616.0273 |
| Soggetto topico |
Disease Models, Animal
Experimentació animal Protecció de la fauna Drets dels animals |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 0-12-809699-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Dedication -- Title Page -- Copyright Page -- Dedication -- Contents -- List of Contributors -- Preface -- Part A - Ethics, resources, and approaches -- Chapter 1 - Ethics in Biomedical Animal Research: The Key Role of the Investigatora -- 1 - Nature and Scope of the Chapter -- 2 - The Subject Matter of Biomedical Animal Research Ethics -- 3 - Why Investigators Should Care About Biomedical Animal Research Ethics -- 3.1 - Investigators are Already Committed to High Ethical Standards -- 3.2 - Ethical Treatment of Animals is Required by Law -- 3.2.1 - General Commitment to Ethical Behavior -- 3.2.2 - Legal Requirements Reflecting General or Specific Ethical Principles -- 3.3 - Ethical Treatment of Animals Promotes Sound Scientific Results -- 3.4 - Ethical Treatment of Animals is Required by Funding Bodies -- 3.5 - Ethical Treatment of Animals is Required by Peer-Reviewed Journals -- 3.5.1 - The ARRIVE Guidelines -- 3.6 - Ethical Treatment of Animals is Essential for Public Support -- 3.7 - Ethical Treatment of Animals is the Right Thing to Do -- 4 - Aspects of Animal Use and Care Relevant to Biomedical Animal Research Ethics -- 5 - Use of Privately Owned Animals in Biomedical Research -- 6 - The Nature of Basic Animal Research -- 6.1 - "Basic" Research as the Search for Knowledge for its Own Sake -- 6.2 - "Basic" Research as the Search for Fundamental, Underlying Mechanisms, and Causes -- 6.3 - What Investigators Mean by "Basic" Animal Research -- 6.4 - Recommendations -- 7 - Why Investigators Play the Key Role in Ensuring the Ethical Conduct of Animal Research Projects -- 7.1 - The Nature of Principles of Biomedical Animal Research Ethics -- 7.2 - The Need for Scientific Expertise in Applying General Ethical Principles -- 7.3 - The Investigator as Captain of the Experimental Ship -- 7.3.1 - Primacy of Project Goals.
7.3.2 - Design and Implementation of Experimental Procedures -- 7.3.3 - The Importance of Sound Science in Ensuring Ethical Animal Experimentation -- 7.4 - The Role of Review Committees and Government Officials in Assessing the Ethical Appropriateness of Animal Experiments -- 7.4.1 - Ethical Review in the United States -- 8 - Sources of Guidance for Investigators in Conducting Ethical Research -- 8.1 - Scientific Resources -- 8.2 - Ethical and Ethically Relevant Resources -- 8.2.1 - Legally Mandated Ethical Principles -- 8.2.2 - Nongovernmental Documents Adherence to Which is Required by Law -- 8.2.3 - Publications of Workshops, Study Committees, and Nongovernmental Entities -- 8.2.4 - Ethical Guidelines of Professional Associations -- 9 - Developing Useful Ethical Guidelines -- 10 - Fundamental Principles of biomedical animal Research Ethics -- F1 - The Biomedical Research Principle -- F2 - The Animal Research Principle -- F3 - The Nuremberg Principle -- F4 - The Pain and Distress Minimization Principle -- F4.1 - Ethical Foundations of the Pain and Distress Minimization Principle -- F4.2 - Qualifications to the Pain and Distress Minimization Principle -- Uncertainty Regarding Minimization -- Imprecision in Estimates of Animal Pain or Distress -- F4.3 - The Incompleteness of the Pain and Distress Minimization Principle -- F5 - The Pain and Distress Justification Principle -- F6 - The Harm Justification Principle -- F6.1 - Determining the Value of a Research Project -- Medical Value of the Project -- Scientific Value of the Project -- F6.2 - Determining Whether the Value of a Project Justifies any Pain, Distress, or Other Harms Caused to the Animals -- Assessing the Project's Medical Value -- Assessing the Nature and Extent of Harms to the Animals. the project's scientific value as the justificatory link between medical value and harms to the animals -- predictability of results and scientific value -- likely limited impact of successful experimental results -- value of unsuccessful projects -- unpredictability of the impact of research results -- F6.3 - Problematic Expressions of the Harm Justification Principle: "Harm-Benefit Analysis" -- why the harm justification principle when properly interpreted should not require likely benefits -- problematic responses to the problem for the harm-benefit analysis of basic animal research -- F6.4 - Further Needed Discussion of the Harm Justification Principle -- F7 - The Harm Minimization Principle -- F8 - The General Justification Principle -- F8.1 - Applying the General Justification Principle to Projects That do and Those That do not Cause Animals Harm -- F8.2 - Why Many Projects That do not Harm Animals Will be Easily Justified -- F9 - The 3Rs Principle -- F9.1 - Redefinition of "Replacement" -- F9.2 - Redefinition of "Refinement" -- F9.3 - The Need for Clarity and Argument -- F10 - The Species-Appropriate Housing Principle -- F10.1 - Definitions of and Ethical Arguments for Research Animal "Well-Being" -- Well-Being as Absence of Pain or Distress -- Well-Being as Including Positive Feelings and Experiences -- Questions About Providing Positive Experiences to Research Animals -- F10.2 - Environmental Enrichment -- Differing Definitions of "Enrichment" -- Differing Views of the Aims of Enrichment -- Potential Effects on Research Results -- F11 - The Appropriate Care Principle -- F12 - The Appreciation Principle -- F13 - The Translation Principle -- 11 - Practical Ethical Guidelines for Investigators -- P1 - Approach all phases and aspects of an animal research project with the aim of making the project ethically as well as ... P2 - Appreciate that as the source of the project's scientific goals, you play the key role in determining whether the proj... -- P3 - Keep in mind that the central question in the ethical assessment of a project is whether its value justifies its use a... -- P4 - To be able to make the strongest case for the medical value of the project, always keep up-to-date information and doc... -- P5 - Design the project with the maximum possible scientific value, by framing sound scientific questions that relate to th... -- P6 - If the project has the potential to cause harms to animals, specifically pain or distress, but also any other signific... -- P7 - In designing and conducting the project, take all reasonable steps to minimize any pain or distress that the animals m... -- P8 - Regard your attending veterinarian as a constant source of information and guidance during all stages of the project -- P9 - Collect, read, and regularly consult publications that enunciate or apply ethical principles relevant to your research -- P10 - Although you should follow legal requirements applicable to the project, when such requirements impose only minimum e... -- 12 - Some Current Difficult Issues in Animal Research Ethics -- 12.1 - The Nature and Weight of Harms to be Justified by the Value of Animal Research Projects -- Unpleasant Experiences Other Than Pain and Distress -- Frustration of an Animal's Nature or Telos -- Killing Research Animals -- 12.2 - Ethical Relevance of Species and Species Characteristics -- The IOM Chimpanzee Report -- The Relative Moral Cost View -- Criteria for Ranking Species -- Number of Ranked Categories -- Research Implications of Species Rankings -- 13 - General Suggestions for Investigators -- S1 - Communicate to the public the nature and potential benefits of your research, and the ethical values and standards you... S2 - Become familiar with some of the animal research ethics literature -- S3 - Participate in discussions of ethical issues relating to biomedical animal research -- References -- Chapter 2 - Psychological Environmental Enrichment of Animals in Research -- 1 - Introduction -- 2 - Enrichment and Welfare -- 2.1 - Why Enrich? -- 2.2 - Common Abnormal Behaviors Seen in Captivity -- 2.3 - Types of Enrichment -- 2.3.1 - Social Enrichment -- 2.3.2 - Physical Enrichment -- 2.3.3 - Food Enrichment -- 2.3.4 - Sensory Enrichment -- 2.3.5 - Occupational Enrichment -- 3 - Enrichment and Animal Models -- 3.1 - Neuroplasticity and Neurogenesis -- 3.2 - Neurological Disorders -- 3.3 - Affective Disorders -- 3.4 - Obesity -- 3.5 - Cancer -- 4 - Enrichment and Experimental Variability -- 5 - Implementing an Enrichment Plan -- 5.1 - Understand the Natural History of the Species you are Trying to Enrich -- 5.2 - Devise Enrichment Plans With Specific Behavioral Outcomes in Mind -- 5.3 - Do no Harm -- 5.4 - Consider the Costs of the Enrichment -- 5.5 - "Listen" to the Animals to Determine Whether They Find the Enrichment Enriching -- 5.6 - Predictability is Important -- 5.7 - Document -- 6 - Example of an Enrichment Plan: Black-Tailed Prairie Dogs (Cynomys ludovicianus) -- 7 - Conclusions -- Acknowledgments -- References -- Further Reading -- Chapter 3 - Large Farm Animal Models of Human Neurobehavioral and Psychiatric Disorders: Methodological and Practical Considera... -- 1 - Animal Models -- 2 - Why Animal Experimental Studies? -- 3 - Animal Models in Biomedical Research -- 4 - Concerns About the Translatability of Findings From Animal Experimental Studies -- 5 - Translational Research -- 6 - Choice of Appropriate Animal Model -- 7 - Where in the Process of Modeling Human Diseases and Developing Putative Therapeutics Have Large Animal Models Been Used?. 8 - Which Model Animal Species Are Classified as Large in Scientific Research?. |
| Record Nr. | UNINA-9910583483703321 |
Conn P. Michael
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| San Diego : , : Elsevier Science & Technology, , 2017 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Animal Models in Chronic Renal Failure : International Workshop on Animal Models for the Assessment of the Effects of Conservative Treatment in Chronic Renal Failure, Heidelberg, January 1987
| Animal Models in Chronic Renal Failure : International Workshop on Animal Models for the Assessment of the Effects of Conservative Treatment in Chronic Renal Failure, Heidelberg, January 1987 |
| Autore | Gretz N |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Basel : , : S. Karger AG, , 1988 |
| Descrizione fisica | 1 online resource (276 pages) |
| Disciplina | 616.6/14027 |
| Altri autori (Persone) |
StrauchM
RoncoClaudio |
| Collana | Issn Series |
| Soggetto topico |
Chronic renal failure - Animal models
Disease Models, Animal Kidney Failure, Chronic - therapy |
| ISBN |
9783318033243
3318033243 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 978-3-8055-4619-5_Cover -- 978-3-8055-4619-5_00I -- 978-3-8055-4619-5_001 -- 978-3-8055-4619-5_009 -- 978-3-8055-4619-5_018 -- 978-3-8055-4619-5_027 -- 978-3-8055-4619-5_039 -- 978-3-8055-4619-5_046 -- 978-3-8055-4619-5_056 -- 978-3-8055-4619-5_064 -- 978-3-8055-4619-5_073 -- 978-3-8055-4619-5_083 -- 978-3-8055-4619-5_094 -- 978-3-8055-4619-5_101 -- 978-3-8055-4619-5_116 -- 978-3-8055-4619-5_126 -- 978-3-8055-4619-5_135 -- 978-3-8055-4619-5_152 -- 978-3-8055-4619-5_159 -- 978-3-8055-4619-5_179 -- 978-3-8055-4619-5_188 -- 978-3-8055-4619-5_192 -- 978-3-8055-4619-5_207 -- 978-3-8055-4619-5_214 -- 978-3-8055-4619-5_220 -- 978-3-8055-4619-5_230 -- 978-3-8055-4619-5_236 -- 978-3-8055-4619-5_245 -- 978-3-8055-4619-5_252 -- 978-3-8055-4619-5_265. |
| Record Nr. | UNINA-9910156329303321 |
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Gretz N
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| Basel : , : S. Karger AG, , 1988 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Disease models & mechanisms : DMM
| Disease models & mechanisms : DMM |
| Pubbl/distr/stampa | [Cambridge], : Co. of Biologists Ltd., ©2008- |
| Soggetto topico |
Biology - Research
Medicine - Research Disease Models, Animal |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1754-8411 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996208309203316 |
| [Cambridge], : Co. of Biologists Ltd., ©2008- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Disease models & mechanisms : DMM
| Disease models & mechanisms : DMM |
| Pubbl/distr/stampa | [Cambridge], : Co. of Biologists Ltd., ©2008- |
| Soggetto topico |
Biology - Research
Medicine - Research Disease Models, Animal Biologie - Recherche Médecine - Recherche Maladies - Modèles animaux |
| Soggetto genere / forma |
Periodical
periodicals. Periodicals. Périodiques. |
| ISSN | 1754-8411 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Altri titoli varianti |
DMM
Disease models and mechanisms |
| Record Nr. | UNINA-9910146005203321 |
| [Cambridge], : Co. of Biologists Ltd., ©2008- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Handbook of animal models of infection : experimental models in antimicrobial chemotherapy / / edited by Oto Zak, Merle Sande
| Handbook of animal models of infection : experimental models in antimicrobial chemotherapy / / edited by Oto Zak, Merle Sande |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | San Diego, CA, : Academic Press, c1999 |
| Descrizione fisica | 1 online resource (1169 p.) |
| Disciplina |
615.329
615.5/8 21 615.58 616.90461 |
| Altri autori (Persone) |
ZakOto
SandeMerle A. <1939-2007.> |
| Soggetto topico |
Animal models in research
Infection - Chemotherapy - Animal models - Evaluation Communicable diseases - Chemotherapy - Animal models - Evaluation Disease Models, Animal Anti-Bacterial Agents - therapeutic use Communicable Diseases - drug therapy Ethics, Medical |
| ISBN |
1-281-79561-5
9786611795610 0-08-053355-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Front Cover; Handbook of Animal Models of Infection; Copyright Page; Contents; List of Section Editors; List of Contributors; Preface; Introduction: The Role of Animal Models in the Evaluation of New Antibodies; Section I: INTRODUCTORY BACKGROUND TO ANIMAL MODELS OF INFECTION; Chapter 1. Early History of Animal Models of Infection; Chapter 2. General Methodologies for Animal Models; Chapter 3. Ethics Committees in Europe-An Overview; Chapter 4. Animal Care and Use Committees-An American Perspective; Chapter 5. Ethical Aspects of the Use of Animal Models of Infection
Chapter 6. The Impact of General Laboratory Animal Health on Experimental Models in Antimicrobial ChemotherapyChapter 7. Non-invasive Monitoring of Infection and Gene Expression in Living Animal Models; Chapter 8. Considerations for Working Safely with Infectious Disease Agents in Research Agents; Chapter 9. Analysis of Genetic Susceptibility to Infection in Mice; Chapter 10. Formulation of Compounds and Determination of Pharmacokinetic Parameters; Chapter 11. Methods for Obtaining Human-like Pharmacokinetic Patterns in Experimental Animals Chapter 12. Modes of Action of Antibiotics and Bacterial Structure: Bacterial Mass Versus their NumbersChapter 13. Activity of Antibiotics Against Adherent/Slow-growing Bacteria Reflecting the Situation in vivo; Section II: BACTERIAL INFECTION MODELS; Chapter 14. The Mouse Peritonitis/Sepsis Model; Chapter 15. Murine Thigh Infection Model; Chapter 16. Mouse Subcutaneous Cotton Thread Model; Chapter 17. Infection after Ionizing Radiation; Chapter 18. Intra-abdominal Abscess; Chapter 19. Mouse Peritonitis Model Using Cecal Ligation and Puncture Chapter 20. Murine Models of Peritonitis Involving a Foreign BodyChapter 21. Rat Polymicrobial Peritonitis Infection Model; Chapter 22. Murine Thigh Suture Model; Chapter 23. Animal Models of Melioidosis; Chapter 24. Low Inoculum Model of Clean Wound Infection; Chapter 25. Translocation of Gut Bacteria During Trauma; Chapter 26. Mouse Models of Campylobacter jejuni Infection; Chapter 27. Suckling Mouse Model of Enterotoxigenic Escherickia coli Infection; Chapter 28. Rabbit Model of Shigellosis; Chapter 29. RITARD Rabbit Model for Studying Vibrio cholerae and Other Enteric Infections Chapter 30. Mouse Model of Helicobacter priori InfectionChapter 31. Animal Models of Helicobacter (ferrets); Chapter 32. Hamster Model of Syphilis; Chapter 33. Guinea-pig Model of Acquired and Congenital Syphilis; Chapter 34. The Guinea-pig Model of Legionnaires Disease; Chapter 35. Murine Models of Tuberculosis; Chapter 36. Beige Mouse Model of Disseminated Mycobacterium avium Complex Infection; Chapter 37. The Armadillo Leprosy Model, with Particular Reference to Lepromatous Neuritis; Chapter 38. Models of Leprosy Infection in Mice; Chapter 39. Hamster Model of Lyme Arthritis Chapter 40. Rabbit Model of Bacterial Conjunctivitis |
| Altri titoli varianti | Animal models of infection |
| Record Nr. | UNINA-9910961410503321 |
| San Diego, CA, : Academic Press, c1999 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Laboratory animal research
| Laboratory animal research |
| Pubbl/distr/stampa | [Seoul] : , : Korean Association for Laboratory Animal Science, , [2005]- |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Laboratory animals
Animals, Laboratory Disease Models, Animal |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 2233-7660 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996205195503316 |
| [Seoul] : , : Korean Association for Laboratory Animal Science, , [2005]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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