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Cutaneous and ocular toxicology
Cutaneous and ocular toxicology
Pubbl/distr/stampa Philadelphia, PA, : Taylor & Francis, Inc., ©2005-
Disciplina 615.9
Soggetto topico Dermatotoxicology
Ocular toxicology
Eye - drug effects
Skin - drug effects
Toxicological Phenomena
Dermatology
Ophthalmology
Toxicology
Soggetto genere / forma Periodical
Periodicals.
ISSN 1556-9535
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910154546203321
Philadelphia, PA, : Taylor & Francis, Inc., ©2005-
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Dermal absorption and decontamination : a comprehensive guide / / edited by Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach
Dermal absorption and decontamination : a comprehensive guide / / edited by Aileen M. Feschuk, Rebecca M. Law, Howard I. Maibach
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (339 pages)
Disciplina 733
Soggetto topico Dermatotoxicology
ISBN 3-031-09222-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- References -- Contents -- Chapter 1: Skin Decontamination with Water: Evidence from In Vivo Human Studies -- Introduction -- Methods -- Search Strategy -- Eligibility -- Data Screening -- Data Extraction and Analysis -- Results -- Study and Participant Characteristics -- Water-Only Chemical Decontamination -- Soap and Water Chemical Decontamination -- Chemical Decontamination with 10% Isopropanol Distilled Water -- Discussion -- References -- Chapter 2: Toward a Harmonized Protocol for Quantifying In Vitro Human Skin Decontamination Efficacy -- Introduction -- Measuring In Vivo Percutaneous Absorption: Animal or Man -- Urine Excretion -- Percutaneous Absorption as Sum of All Residues in Body: Animal Only -- Percutaneous Absorption as Measurement of Material Lost from Skin Surface -- Chemical Analytic Methods -- Breath Test to Measure Percutaneous Absorption -- Animal Models to Study Percutaneous Absorption -- Rhesus Monkeys -- Miniature Pigs -- Hairless Guinea Pigs -- Hairless Rats -- Studying PA Using In Vitro Models -- Receptor Fluids -- Human Skin Models -- Computer Modeling -- RSDL -- French Test Standard Method of Quantifying Decontamination Effectiveness -- Conclusion -- References -- Chapter 3: In Vitro Human Skin Decontamination with Water: Chemical Warfare Agents or Simulants -- Introduction -- Materials and Methods -- Search Strategy -- Eligibility -- Data Screening -- Data Extraction and Analysis -- Results -- Study Characteristics -- Water-Only Decontamination -- Soap and Water Decontamination -- Water-Only and Soap and Water Decontamination -- Discussion -- References -- Chapter 4: In Vitro Human Skin Decontamination with Water: Occupational Contaminants -- Introduction -- Materials and Methods -- Search Strategy -- Eligibility -- Data Screening -- Data Extraction and Analysis -- Results -- Study Characteristics.
Water-Only Decontamination -- Soap and Water Decontamination -- Water-Only and Soap and Water Decontamination -- Discussion -- References -- Chapter 5: Skin Decontamination with Water: Evidence from In Vivo Animal Models -- Introduction -- Methods -- Search Strategy -- Eligibility -- Data Screening -- Data Extraction and Analysis -- Results -- Study Characteristics -- Water-Only Chemical Decontamination -- Soap and Water -- Soap and Water Versus Water -- Discussion -- Conclusion -- References -- Chapter 6: Skin Decontamination with Water: Evidence from In Vitro Animal Models -- Introduction -- Methods -- Results -- Study Characteristics -- Comparing Water to Soap and Water Decontamination -- Comparing Soap and Water to Other Decontamination Solutions -- Comparing Water to Other Decontamination Solutions -- Discussion -- Conclusion -- References -- Chapter 7: Dermal Decontamination with Readily Available Dry Products -- Introduction -- Materials and Methods -- Results -- Study Characteristics -- Study Findings -- Discussion -- Conclusion -- References -- Chapter 8: A Review of Reactive Skin Decontamination Lotion Efficacy -- Introduction -- Methods -- Results -- Discussion -- Conclusion -- References -- Chapter 9: Aqueous Suspensions of Fuller's Earth Potentiate the Adsorption Capacities of Paraoxon and Improve Skin Decontamination Properties -- Introduction -- Materials and Methods -- Material -- Toxicity -- In Vitro Cell Toxicity -- In Vivo Danio rerio Toxicity -- Ex Vivo Cell Diffusion Assays -- Skin Explants -- Decontamination Protocols -- Collection and Treatment of Samples -- Quantification by HPLC-UV -- Ex Vivo Evaluation of a Skin Decontaminant -- Statistical Analysis -- Results -- Toxicity of Fuller's Earth Suspensions -- FE Suspensions' Supernatant Cytotoxicity -- In Vivo Toxicity of FE Suspensions -- Ex Vivo Decontamination Assays.
Differences in Paraoxon Penetration Kinetics Through Pig Ear Skin and Human Abdominal Skin -- Efficacy of FE Suspension Compared to FE Powder and Water -- Relationship Between FE Suspensions' Concentration and Decontamination Efficiency -- Comparison of Skin Origins and of Decontamination Methods -- Discussion -- Conclusion -- References -- Chapter 10: Development of a Next Generation Military Skin Decontaminant: Initial Efficacy Studies of Zirconium Hydroxide -- Introduction -- Materials and Methods -- Chemicals -- Experimental Approach -- Screening Experiment -- Decontamination of Porcine Skin -- Results -- Screening Experiment Using Strat-M™ -- Decontamination Efficacy with Porcine Skin -- Discussion -- References -- Chapter 11: Findings from the PHOENIX Project: 'Protocols for Hair and the Optimisation of Existing and Novel Decontamination Interventions Through Experimentation' -- Introduction -- Speed Is Critical -- The Importance of Disrobing -- Dry Decontamination of Skin Is an Effective Intervention When Initiated in a Timely Manner -- There Are Optimised Parameters for Mass Decontamination Showering -- Decontamination Methods Have Variable Efficacy for Contaminated Hair -- Decontamination Must be Casualty Focused to Facilitate Compliance -- The PHOENIX Project -- Discussion and Conclusions -- Use of a Benzyl Salicylate (BeS) as a Novel Simulant and What This Adds to Our Understanding -- Hair-Wicking and the Protective Effect of Longer Hair -- Urine Analysis Raises More Questions Than Answers -- Future Directions for Mass Decontamination -- References -- Chapter 12: Twenty Clinically Pertinent Factors/Observations for Percutaneous Absorption in Humans -- Introduction -- Factors in Percutaneous Absorption -- 1. What are the relevant physicochemical properties of the medication/chemical?.
2. What effects do the vehicle/formulation of the product have on drug absorption? -- 3. What effects do the conditions of drug exposure (dose, duration, surface area, and frequency of exposure) have on drug absorption? -- 4. Do the skin appendages (hair follicles, sebaceous glands, apocrine and eccrine sweat glands) have a role in topical drug absorption? -- 5. How do the skin sites of application affect absorption? -- 6. What population variability factors affect topical absorption? -- 7. How do skin surface conditions affect topical drug absorption? -- 8. How does skin health and skin integrity affect topical absorption? -- 9. How does substantivity and binding to the different skin components affect topical absorption? -- 10. How does topical application result in systemic distribution of the drug or chemical? -- 11. How, if at all, does exfoliation affect topical absorption? -- 12. Does washing affect topical absorption? -- 13. Does rubbing or massaging affect topical absorption? -- 14. Can medications or chemicals be transferred from one person to another through skin contact, clothing, or contact with an inanimate surface? -- 15. How is topical absorption affected if a drug or chemical is volatile? -- 16. Does metabolic transformation occur during topical absorption, and if so, how and what? Does cutaneous metabolism occur? -- 17. Does photochemical transformation occur during topical absorption, and if so, how and what? -- 18. How does metabolism affect excretion kinetics of the drug or chemical? and how does excretion kinetics relate to topical absorption? -- 19. How does lateral spread affect percutaneous absorption? -- 20. For investigators, does the method of determining percutaneous absorption influence the results and the interpretation of study results? -- Summary -- References.
Chapter 13: Lateral Spread and Percutaneous Penetration: An Overview -- Introduction -- Definition -- Consequences of Lateral Spread -- Evidence for the Lateral Spread Phenomenon -- Spread Pattern -- Factors Affecting Lateral Spread -- Molecular Weight -- Time -- Time-Dependent Redistribution -- Physicochemical Properties -- Formulation -- Viscosity -- Skin Surface Topography -- Anatomical Sites -- Natural Lateral Spread Phenomena -- Summary and Future Needs -- Conclusions -- References -- Chapter 14: Regional Variation in Percutaneous Absorption: Evidence from In Vitro Human Models -- Introduction -- Methods -- Search Strategy -- Eligibility -- Data Screening -- Data Extraction and Analysis -- Results -- Study Characteristics -- Study Results -- Study 1: Smith et al. (1961) -- Study 2: Ritschel et al. (1989) -- Study 3: Harada et al. (1993) -- Study 4: Ogiso et al. (2002) -- Study 5: Schmitt et al. (2010) -- Study 6: Rolland et al. (2011) -- Study 7: Trabaris et al. (2012) -- Study 8: Elmahdy et al. (2020) -- Discussion -- Conclusions Regarding Regional Variation in Percutaneous Absorption -- Study Limitations -- Practical Application of Results -- Conclusions -- References -- Chapter 15: Experimental Variability in TEWL Data -- Introduction -- Materials and Methods -- Results -- Experimental Variables -- Sample Size and Power -- Evaporimeter Standardization -- Technician Training -- Room Temperature -- Environmental Variables -- Season -- Altitude -- Individual Variables -- Age -- Anatomic Site -- Sex -- Skin of Color -- Circadian Rhythm -- Sleep -- Food -- Body Mass Index (BMI) -- Smoking Status -- Eccrine Sweating -- Menstrual Cycle -- Discussion -- Conclusion -- References -- Chapter 16: Relationships Between Skin of Color and the TEWL Barrier -- Introduction -- Materials and Methods -- Results -- No TEWL Differences -- TEWL Differences.
Discussion.
Record Nr. UNINA-9910616362303321
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Dermal exposure
Dermal exposure
Pubbl/distr/stampa Geneva : , : World Health Organization, , [2014]
Descrizione fisica 1 online resource (529 p.)
Disciplina 616.5
Collana Environmental health criteria
Soggetto topico Skin - Physiology
Dermatotoxicology
Hazardous substances - Risk assessment
Soggetto genere / forma Electronic books.
ISBN 92-4-069278-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ; 1 Summary -- ; 2 Introduction and scope -- ; 3 General background -- ; 4 Sources of dermal exposure.
Record Nr. UNINA-9910466412203321
Geneva : , : World Health Organization, , [2014]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Dermal exposure
Dermal exposure
Pubbl/distr/stampa Geneva : , : World Health Organization, , [2014]
Descrizione fisica 1 online resource (529 p.)
Disciplina 616.5
Collana Environmental health criteria
Soggetto topico Skin - Physiology
Dermatotoxicology
Hazardous substances - Risk assessment
ISBN 92-4-069278-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ; 1 Summary -- ; 2 Introduction and scope -- ; 3 General background -- ; 4 Sources of dermal exposure.
Record Nr. UNINA-9910796165903321
Geneva : , : World Health Organization, , [2014]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Dermal exposure
Dermal exposure
Pubbl/distr/stampa Geneva : , : World Health Organization, , [2014]
Descrizione fisica 1 online resource (529 p.)
Disciplina 616.5
Collana Environmental health criteria
Soggetto topico Skin - Physiology
Dermatotoxicology
Hazardous substances - Risk assessment
ISBN 92-4-069278-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ; 1 Summary -- ; 2 Introduction and scope -- ; 3 General background -- ; 4 Sources of dermal exposure.
Record Nr. UNINA-9910816447403321
Geneva : , : World Health Organization, , [2014]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Drug eruptions / / editors : Haur Yueh Lee, Daniel Creamer
Drug eruptions / / editors : Haur Yueh Lee, Daniel Creamer
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2022]
Descrizione fisica 1 online resource (347 pages)
Disciplina 616.5
Collana Updates in clinical dermatology
Soggetto topico Dermatotoxicology
Drugs - Side effects
Skin - Inflammation
ISBN 3-031-09388-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Preface -- Introduction -- Clinical Approach to a Patient with a Cutaneous ADR -- Drug Causality in Cutaneous ADRs -- Classification of the Cutaneous ADRs -- Mechanistic Classification -- Drug Hypersensitivity Reactions -- Non-hypersensitivity -- Phenotypic Classification -- Contents -- Contributors -- Part I: General Considerations -- Pharmacogenetics of Cutaneous Adverse Drug Reactions -- 1 Introduction -- 2 Abacavir Hypersensitivity and HLA-B*57:01 -- 3 Carbamazepine Hypersensitivity -- 3.1 Carbamazepine Metabolism Genes -- 3.2 Carbamazepine and HLA Alleles -- HLA-B*15:02 -- HLA-A*31:01 -- 3.3 Carbamazepine and Other HLA Alleles -- 3.4 Carbamazepine and T Cell Receptor Variation -- 4 Aromatic Antiepileptics and Hypersensitivity -- 5 Allopurinol Hypersensitivity and HLA-B*58:01 -- 6 Dapsone Hypersensitivity -- 7 Other Drugs -- 8 Discussion -- References -- Mechanisms of Drug Hypersensitivity -- 1 Introduction -- 2 Models of Drug Antigen Presentation -- 3 Genetic Factors in Drug Hypersensitivity -- 3.1 Genetic Factor in Immediate-Type Drug Hypersensitivity -- 3.2 Genetic Factor in Delayed-Type Drug Hypersensitivity -- Allopurinol -- Aromatic Anticonvulsants -- Abacavir -- Other Drugs -- 4 Drug Metabolism in SCARs -- 5 Immune Mechanisms in DH -- 5.1 Immediate-Type: IgE-Mediated DH -- 5.2 Delayed-Type: T Cells Mediated DH -- MPE (Type Iva) -- DRESS Syndrome (Type IVb) -- SJS/TEN (Type IVc) -- Granulysin -- Perforin/Granzyme B Pathway -- NK Cells -- Fas-FasL Interaction -- Annexin A1-FPR1 Interaction -- Cytokines/Chemokines Involved in the Cell Immunity of SJS/TEN -- AGEP (Type IVd) -- 6 T Cell Receptor (TCR) Repertoire in Drug Hypersensitivity -- 7 Conclusion -- References -- Histopathology of Cutaneous Adverse Drug Reactions -- 1 Introduction -- 2 Inflammatory Patterns in CADR -- 2.1 Spongiotic Reaction Pattern.
2.2 Interface Dermatitis Pattern -- 3 Non-specific Histological Aspects of Cutaneous ADRs -- 4 Drug-Induced Exanthem -- 5 Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) -- 6 Acute Generalized Exanthematous Pustulosis (AGEP) -- 7 Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) -- 8 Fixed Drug Eruption (FDE) -- 9 Symmetrical Drug-Related Intertriginous and Flexural Exanthem (SDRIFE) -- 10 Problems of Differential Diagnosis in Drug Eruption Dermatopathology -- References -- Skin Tests in Evaluating Drug Eruptions -- 1 Introduction -- 2 Skin Tests for Immediate Drug Eruptions -- 3 Skin Tests for Nonimmediate Drug Eruptions -- 4 Other Skin Tests -- 5 Conclusions -- References -- In Vitro Drug Allergy Testing -- 1 Introduction -- 2 Immediate Drug Hypersensitivity Reactions -- 2.1 Acute Phase Mediators -- 2.2 Immunoassays -- 2.3 Basophil Activation Test (BAT) -- 3 Delayed Drug Hypersensitivity Reactions -- 3.1 Lymphocyte Proliferation Assay (LPA), Lymphocyte Transformation Test (LTT) -- 3.2 Flow Cytometry -- 3.3 Enzyme-Linked Immunospot (ELISpot) and Enzyme-Linked Immunosorbent Assay (ELISA) -- 3.4 Practical Utility of In Vitro Tests -- 4 Conclusions -- References -- Part II: Reaction Patterns -- Drug-Induced Urticaria -- 1 Introduction -- 2 Pathophysiology -- 2.1 Immunologically Mediated Reactions -- IgE Antibody-Dependent Reactions -- Formation of Immune Complexes -- 2.2 Non-Immunological Reactions -- Direct Mast Cell Degranulation -- Kinin-Mediated Angioedema -- Interference with the Arachidonic Metabolism -- 3 Evaluation of a Patient with Suspected DIU -- 4 Investigating DIU -- 4.1 In Vitro Testing -- Tests to Aid Diagnosis -- Tests to Help Identify Culprit Drug -- 4.2 In Vivo Testing -- 5 Management of DIU -- 6 Medications Associated with DIU.
6.1 Aspirin and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) -- 6.2 Opiates -- 6.3 Angiotensin-Converting Enzyme Inhibitors (ACEi) -- 6.4 Others -- 7 Summary -- References -- Exanthematous Drug Eruptions -- 1 Introduction -- 2 Pathogenesis -- 3 Epidemiology -- 4 Clinical Features -- 5 Offending Agents -- 6 Diagnosis -- 7 Management -- 8 Conclusion and Future Directions -- References -- Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis -- 1 Introduction -- 2 Medication Risk -- 3 Pathophysiology -- 4 Clinical Presentation -- 5 Management and Treatment -- 6 Supportive Care -- 7 Local Management of Skin and Mucous Membranes -- 8 Immunomodulatory Approaches -- 9 Long-Term Follow-Up -- 10 Tests to Identify the Culprit Drug -- 11 Prevention of SJS/TEN -- References -- Acute Generalised Exanthematous Pustulosis -- 1 Introduction -- 2 Epidemiology -- 3 Pathophysiology -- 4 Pathology -- 5 Culprit Drugs -- 6 Clinical Features -- 7 Differential Diagnosis -- 8 Investigations -- 9 Management -- References -- Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) -- 1 Introduction -- 2 Epidemiology -- 3 Drug Causality -- 4 Pathophysiology -- 5 Clinical Features -- 6 Histopathology -- 7 Long-Term Sequelae of DRESS -- 8 Differential Diagnosis -- 9 Prognosis and Management -- 10 Conclusion -- References -- Fixed Drug Eruptions and Generalized Bullous Fixed Drug Eruptions -- 1 Introduction -- 2 Epidemiology -- 3 Pathophysiology -- 3.1 Histopathology -- 3.2 Pathomechanism -- 4 Clinical Features -- 4.1 Clinical Presentation -- 4.2 Differential Diagnosis -- 4.3 Culprit Drugs -- 4.4 Prognosis -- 5 Investigations -- 6 Management -- References -- Lichenoid Drug Eruptions -- 1 Introduction -- 2 Epidemiology -- 3 Description of Features -- 4 Drug Causality -- 4.1 Biologics.
4.2 Immune Checkpoint Inhibitors -- 5 Variations in Clinical Features of LDE -- 6 Histological Findings -- 7 Pathogenesis -- 7.1 Treatment -- References -- Drug-Induced Connective Tissue Disorders -- 1 Drug-Induced Lupus Erythematosus -- 1.1 Epidemiology -- 1.2 Drug Causality in Drug-Induced Lupus Erythematosus -- 1.3 Pathophysiology -- Genetic Susceptibility -- Effects on Adaptive Immunity -- Effects on Innate Immunity -- Clinical Features -- Drug-Induced Systemic Lupus Erythematosus -- Drug-Induced Subacute Cutaneous Lupus Erythematosus -- 1.4 Diagnosis -- Serological Profile -- 1.5 Management -- 2 Drug-Induced Dermatomyositis -- 3 Drug-Induced Scleroderma -- References -- Drug-Induced Vasculitis -- 1 Introduction -- 2 Clinical Approach -- 3 Drugs Commonly Associated with Cutaneous Vasculitis -- 3.1 Antibiotics -- 3.2 Anti-TNF-α Agents -- 3.3 Propylthiouracil -- 3.4 Cocaine/Levamisole -- 3.5 Cancer Immunotherapy -- 4 Pathogenesis -- 5 Conclusion -- References -- Drug-Induced Autoimmune Bullous Diseases -- 1 Drug-Induced Pemphigus -- 1.1 Clinical Features -- 1.2 Drug Causality and Pathophysiology -- 2 Drug-Induced Bullous Pemphigoid (DIBP) -- 2.1 Clinical Presentation/Investigations -- 2.2 Pathophysiology -- 2.3 Drug Causality -- 3 Drug-Induced Linear IgA Bullous Dermatosis (LABD) -- 3.1 Clinical Presentation -- 3.2 Pathophysiology -- 3.3 Drug Causality -- 4 Drug-Induced Epidermolysis Bullosa Acquisita (EBA) -- 4.1 Management of Drug-induced Autoimmune Blistering Diseases -- 5 Conclusion -- References -- Other Drug-Induced Inflammatory Skin Reactions -- 1 Drug-Induced Granulomatous Reactions -- 1.1 Interstitial Granulomatous Drug Reaction (IGDR) -- 1.2 Drug-Induced Sarcoidosis -- 1.3 Drug-Induced Granuloma Annulare (GA) -- 1.4 Drug-Induced Accelerated Rheumatoid Nodulosis.
2 Drug-Induced Neutrophilic Reactions -- 2.1 Drug-Induced Sweet's Syndrome -- 3 Drug-Induced Pityriasis Rosea (PR)-like Reactions -- 4 Drug-Induced Panniculitis -- 4.1 Drug-Induced Erythema Nodosum -- Clinical Features -- 4.2 Drug-Induced (Primarily Lobular) Neutrophilic Panniculitis -- Introduction -- Pathophysiology -- Clinical Features -- 5 Drug-Induced Eczematous Reactions -- 6 Drug-Induced Acneiform Eruptions (Drug-Induced Acne) -- References -- Drug-Induced Photosensitivity -- 1 Introduction -- 2 Epidemiology -- 3 Pathogenesis -- 4 Systemic Drug Phototoxicity and Common Culprits -- 5 Clinical Presentation of Drug Photosensitivity -- 6 Wavelength Dependency -- 7 Investigations for Drug-Induced Phototoxicity -- 8 Regulatory Requirements for Photosafety Evaluation -- 9 Topical Photoallergy -- 10 Other Possible Effects of Drug Photosensitivity -- 11 Management -- 12 Practical Advice -- 13 Conclusions -- References -- Drug-Induced Pruritus Without Primary Rash -- 1 Definition -- 2 Overall Prevalence -- 3 Categories -- 4 Pathogenesis of Drug-Induced Pruritus -- 4.1 The Itch Pathway -- 4.2 Specific Drugs Inducing Pruritus -- Opioids -- Chloroquine -- Hydroxyethyl Starch -- Drugs Inducing Cholestasis -- Anticancer Therapies -- Other Drugs -- 5 Diagnosis -- 6 Treatment -- 7 Conclusion -- References -- Drug-Induced Nail Changes -- 1 Introduction -- 2 Human Nail Unit Anatomy with Pathophysiological Correlation -- 3 Approach to Nail Unit Drug Reaction -- 4 Common Examples of Drugs Causing Specific Clinical Findings in the Nail Unit -- 4.1 Nail Fold -- 4.2 Nail Bed -- 4.3 Nail Plate/Matrix -- 4.4 Nail Matrix Melanocytes -- Entire Nail Unit -- 5 Management Principles for Nail Unit Drug Reactions -- References -- Drug-Induced Hair Changes -- 1 Introduction -- 2 The Hair Cycle and Hair Immune System.
3 Clinical Assessment.
Record Nr. UNINA-9910624394903321
Cham, Switzerland : , : Springer, , [2022]
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Journal of toxicology Cutaneous and ocular toxicology
Journal of toxicology Cutaneous and ocular toxicology
Pubbl/distr/stampa New York, NY, : Marcel Dekker, 1982-2004
Disciplina 615
Soggetto topico Ocular toxicology
Dermatotoxicology
Eye - drug effects
Skin - drug effects
Toxicology
Soggetto genere / forma Periodical
ISSN 1532-2505
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910222248103321
New York, NY, : Marcel Dekker, 1982-2004
Materiale a stampa
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The poisoned weed : plants toxic to skin / / Donald G. Crosby
The poisoned weed : plants toxic to skin / / Donald G. Crosby
Autore Crosby Donald G.
Pubbl/distr/stampa Oxford, [England] : , : Oxford University Press, , 2004
Descrizione fisica 1 online resource (279 p.)
Disciplina 616.5/07
Soggetto topico Dermatotoxicology
Poisonous plants
Plant toxins
Soggetto genere / forma Electronic books.
ISBN 1-280-50236-3
1-60256-841-3
0-19-803542-X
0-19-530349-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; ONE: THE SETTING; TWO: POISON OAKS, POISON IVIES, AND RELATIVES; THREE: OTHER ALLERGENIC PLANTS; FOUR: PHOTOTOXIC AND IRRITANT PLANTS; FIVE: ALLERGENS RELATED TO URUSHIOL; SIX: OTHER PLANT ALLERGENS; SEVEN: PHOTOTOXIC AND IRRITANT CONSTITUENTS; EIGHT: EXPOSURE; NINE: ADVERSE EFFECTS; TEN: PREVENTION AND TREATMENT; APPENDICES; REFERENCES; GLOSSARY; INDEX OF PLANT NAMES; INDEX OF CHEMICAL COMMON NAMES; GENERAL INDEX
Record Nr. UNINA-9910449719703321
Crosby Donald G.  
Oxford, [England] : , : Oxford University Press, , 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The poisoned weed : plants toxic to skin / / Donald G. Crosby
The poisoned weed : plants toxic to skin / / Donald G. Crosby
Autore Crosby Donald G.
Pubbl/distr/stampa Oxford, [England] : , : Oxford University Press, , 2004
Descrizione fisica 1 online resource (279 p.)
Disciplina 616.5/07
Soggetto topico Dermatotoxicology
Poisonous plants
Plant toxins
ISBN 0-19-770186-8
1-280-50236-3
1-60256-841-3
0-19-803542-X
0-19-530349-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; ONE: THE SETTING; TWO: POISON OAKS, POISON IVIES, AND RELATIVES; THREE: OTHER ALLERGENIC PLANTS; FOUR: PHOTOTOXIC AND IRRITANT PLANTS; FIVE: ALLERGENS RELATED TO URUSHIOL; SIX: OTHER PLANT ALLERGENS; SEVEN: PHOTOTOXIC AND IRRITANT CONSTITUENTS; EIGHT: EXPOSURE; NINE: ADVERSE EFFECTS; TEN: PREVENTION AND TREATMENT; APPENDICES; REFERENCES; GLOSSARY; INDEX OF PLANT NAMES; INDEX OF CHEMICAL COMMON NAMES; GENERAL INDEX
Record Nr. UNINA-9910783457503321
Crosby Donald G.  
Oxford, [England] : , : Oxford University Press, , 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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The poisoned weed : plants toxic to skin / / Donald G. Crosby
The poisoned weed : plants toxic to skin / / Donald G. Crosby
Autore Crosby Donald G
Edizione [1st ed.]
Pubbl/distr/stampa New York, : Oxford University Press, 2004
Descrizione fisica 1 online resource (279 p.)
Disciplina 616.5/07
Collana Oxford scholarship online
Soggetto topico Dermatotoxicology
Poisonous plants
Plant toxins
ISBN 0-19-028870-1
0-19-770186-8
1-280-50236-3
1-60256-841-3
0-19-803542-X
0-19-530349-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto CONTENTS; ONE: THE SETTING; TWO: POISON OAKS, POISON IVIES, AND RELATIVES; THREE: OTHER ALLERGENIC PLANTS; FOUR: PHOTOTOXIC AND IRRITANT PLANTS; FIVE: ALLERGENS RELATED TO URUSHIOL; SIX: OTHER PLANT ALLERGENS; SEVEN: PHOTOTOXIC AND IRRITANT CONSTITUENTS; EIGHT: EXPOSURE; NINE: ADVERSE EFFECTS; TEN: PREVENTION AND TREATMENT; APPENDICES; REFERENCES; GLOSSARY; INDEX OF PLANT NAMES; INDEX OF CHEMICAL COMMON NAMES; GENERAL INDEX
Record Nr. UNINA-9910826890403321
Crosby Donald G  
New York, : Oxford University Press, 2004
Materiale a stampa
Lo trovi qui: Univ. Federico II
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