Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso
| Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso |
| Edizione | [1st ed.] |
| Pubbl/distr/stampa | Hoboken, N.J., : Wiley-Blackwell, c2011 |
| Descrizione fisica | 1 online resource (420 p.) |
| Disciplina | 616.99/4042 |
| Altri autori (Persone) |
GiordanoAntonio
MacalusoMarcella |
| Collana | Cancer epigenetics |
| Soggetto topico |
Cancer - Genetic aspects
Cancer - Treatment Epigenesis DNA - Methylation |
| ISBN |
9786613110688
9781283110686 1283110687 9781118005736 1118005732 9781118005743 1118005740 9781118005729 1118005724 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
(Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? / by Micaela Montanari, Antonio Giordano, Marcella Cintorino and Marcella Macaluso -- Section II: Epigenetics and Cell Development, Senescence and Differentiation -- Epigenetic in skeletal muscle Development? / by Cristina Giacinti and Antonio Giordano -- Epigenetic control in cellular senescence? / by Heike Helmbold, Wolfgang Deppert, and Wolfgang Bohn -- Epigenetic modulation in cell development and differentiation? / by Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca and Francesca Pentimalli -- Section III: Epigenetics and Gene Transcription -- Epigenetic control of gene transcription? / by Christian Bronner, Mayada Achour, Thierry Chataigneau and Valerie B. Schini-Kerth -- Epigenetics, microRNAs and cancer: an update? / by Giuseppe Russo1, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia Cito, Debora Muresu, Flavio Rizzolio and Antonio Giordano -- Section IV: Epigenetics and Cancer -- Epigenetics and Cancer? by Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon, Alexander Mazo, and Richard G. Pestell --
The MBD4/MED1 Protein in DNA Repair, DNA Demethylation, Disease and Cancer? / Serena Buontempo, Mara Sannai and Alfonso Bellacosa -- Epigenetics in pediatric cancers? by Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, Rossella Rota -- Epigenetic mechanisms in cancer formation and progression? by Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, Michele Maio -- Section V: Epigenetics and Anticancer Drug Development and Therapy -- Recent advances in the field of stem cell research: towards the definition of the epigenetic and genetic codes of pluripotency? / by Gaetano Romano -- Potential of Heat Shock Protein Targeting for Human Therapy? / by Laszlo Otvos, Jr -- Advancements in Stem Cell Therapy & Research? /by Andrew Puca and Antonio Giordano. |
| Record Nr. | UNINA-9910140979703321 |
| Hoboken, N.J., : Wiley-Blackwell, c2011 | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA methylation : patterns, functions and roles in disease / / Kathleen Holland, editor
| DNA methylation : patterns, functions and roles in disease / / Kathleen Holland, editor |
| Pubbl/distr/stampa | Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016] |
| Descrizione fisica | 1 online resource (225 pages) : illustrations |
| Disciplina | 572.8/6 |
| Collana | Genetics - research and issues |
| Soggetto topico | DNA - Methylation |
| ISBN | 1-5361-0261-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910148697203321 |
| Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016] | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
| DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin |
| Autore | Vaniushin B. F |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (164 p.) |
| Disciplina | 572.8/2 |
| Altri autori (Persone) | AshapkinVasili V |
| Soggetto topico |
Plant biochemical genetics
DNA - Methylation |
| Soggetto genere / forma | Electronic books. |
| ISBN | 1-60876-414-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""DNA METHYLATION IN PLANTS""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""INTRODUCTION""; ""IS THE CYTOSINE DNA METHYLATION AT ALL IMPORTANT?""; ""ARE TRANSPOSABLE SEQUENCES SILENCED BY CYTOSINE METHYLATION?""; ""ARE MULTICOPY GENES SILENCED BY CYTOSINE METHYLATION?""; ""IS GENE SILENCING ALWAYS ASSOCIATED WITH THEIR METHYLATION?""; ""ARE THE EPIGENETIC CHANGES INHERITABLE?""; ""CYTOSINE DNA-METHYLTRANSFERASES: HOW MANY OF THEM ARE NEEDED?""; ""1. MET1 IS A MAJOR CPG-SPECIFIC MAINTENANCE PLANT DNA-METHYLTRANSFERASE""
""2. CHROMOMETHYLASE IS A PLANT SPECIFIC DNA-METHYLTRANSFERASE""""3. DRM ARE THE PLANT DE NOVO DNA-METHYLTRANSFERASES""; ""ARE THERE SIGNALS FOR THE DE NOVO DNA METHYLATION?""; ""IS DNA METHYLATION ITSELF REGULATED BY DNA METHYLATION?""; ""H3 HISTONE METHYLATION OR HOW DNA METHYLATION PATTERNS ARE ESTABLISHED AND MAINTAINED?""; ""IS DSRNA AN ANOTHER WAY OF ESTABLISHING DNA METHYLATION PATTERNS?""; ""ADENINE DNA METHYLATION""; ""N6-METHYLADENINE IN DNA OF EUKARYOTES""; ""ADENINE DNA-METHYLTRANSFERASES""; ""PUTATIVE ROLE OF ADENINE DNA METHYLATION IN PLANTS""; ""CONCLUSION"" ""ACKNOWLEDGEMENTS""""REFERENCES""; ""INDEX"" |
| Record Nr. | UNINA-9910455191603321 |
Vaniushin B. F
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| New York, : Nova Biomedical Books, c2009 | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
| DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin |
| Autore | Vaniushin B. F |
| Pubbl/distr/stampa | New York, : Nova Biomedical Books, c2009 |
| Descrizione fisica | 1 online resource (164 p.) |
| Disciplina | 572.8/2 |
| Altri autori (Persone) | AshapkinVasili V |
| Soggetto topico |
Plant biochemical genetics
DNA - Methylation |
| ISBN | 1-60876-414-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
""DNA METHYLATION IN PLANTS""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""INTRODUCTION""; ""IS THE CYTOSINE DNA METHYLATION AT ALL IMPORTANT?""; ""ARE TRANSPOSABLE SEQUENCES SILENCED BY CYTOSINE METHYLATION?""; ""ARE MULTICOPY GENES SILENCED BY CYTOSINE METHYLATION?""; ""IS GENE SILENCING ALWAYS ASSOCIATED WITH THEIR METHYLATION?""; ""ARE THE EPIGENETIC CHANGES INHERITABLE?""; ""CYTOSINE DNA-METHYLTRANSFERASES: HOW MANY OF THEM ARE NEEDED?""; ""1. MET1 IS A MAJOR CPG-SPECIFIC MAINTENANCE PLANT DNA-METHYLTRANSFERASE""
""2. CHROMOMETHYLASE IS A PLANT SPECIFIC DNA-METHYLTRANSFERASE""""3. DRM ARE THE PLANT DE NOVO DNA-METHYLTRANSFERASES""; ""ARE THERE SIGNALS FOR THE DE NOVO DNA METHYLATION?""; ""IS DNA METHYLATION ITSELF REGULATED BY DNA METHYLATION?""; ""H3 HISTONE METHYLATION OR HOW DNA METHYLATION PATTERNS ARE ESTABLISHED AND MAINTAINED?""; ""IS DSRNA AN ANOTHER WAY OF ESTABLISHING DNA METHYLATION PATTERNS?""; ""ADENINE DNA METHYLATION""; ""N6-METHYLADENINE IN DNA OF EUKARYOTES""; ""ADENINE DNA-METHYLTRANSFERASES""; ""PUTATIVE ROLE OF ADENINE DNA METHYLATION IN PLANTS""; ""CONCLUSION"" ""ACKNOWLEDGEMENTS""""REFERENCES""; ""INDEX"" |
| Record Nr. | UNINA-9910778005803321 |
Vaniushin B. F
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| New York, : Nova Biomedical Books, c2009 | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Methylation Mechanism / / edited by Metin Budak and Mustafa Yıldız
| DNA Methylation Mechanism / / edited by Metin Budak and Mustafa Yıldız |
| Pubbl/distr/stampa | London, United Kingdom : , : IntechOpen, , 2020 |
| Descrizione fisica | 1 online resource (161 pages) : illustrations (some color) |
| Disciplina | 574.873282 |
| Collana | Biochemistry |
| Soggetto topico | DNA - Methylation |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910688589503321 |
| London, United Kingdom : , : IntechOpen, , 2020 | ||
| Lo trovi qui: Univ. Federico II | ||
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Epigenetics
| Epigenetics |
| Pubbl/distr/stampa | Chichester, [England] : , : John Wiley & Sons, , 1998 |
| Descrizione fisica | 1 online resource (320 p.) |
| Disciplina |
572.8
572.865 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Novartis Foundation Symposium |
| Soggetto topico |
Genetic regulation
Epigenesis DNA - Methylation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-282-34808-6
9786612348082 0-470-51550-3 0-470-51551-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
EPIGENETICS; Participants; Contents; Introduction; Gene silencing by methyl-CpG- binding proteins; DNAmethylation, nucleosornes and the inheritance okhromatin structure and function; General discussion I; Heritable chromatin states induced by the Polycomb and trithorax group genes; The dynamics of globin gene expression and position effects; Multiple epigenetic events regulate mating-type switching of fission yeast; General discussion I1; Nuclear organization and silencing: trafficking of Sir proteins; Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon
Transgene-promoted epigenetic switches of chalcone synthase activity in petunia plantsGeneral discussion I11; Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns; The host defence function of genomic methylation patterns; Mammalian X chromosome inactivation; Methylation dynamics, epigenetic fidelity and X chromosome structure; General discussion IV; Imprinting and gene silencing in mice and DrosophiZa; Making sense of imprinting the mouse and human IGF2R loci; Imprinted genes in the Prader-Willi deletion; Final general discussion SummaryIndex of contributors; Subject index |
| Record Nr. | UNINA-9910144559903321 |
| Chichester, [England] : , : John Wiley & Sons, , 1998 | ||
| Lo trovi qui: Univ. Federico II | ||
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Epigenetics
| Epigenetics |
| Pubbl/distr/stampa | Chichester, [England] : , : John Wiley & Sons, , 1998 |
| Descrizione fisica | 1 online resource (320 p.) |
| Disciplina |
572.8
572.865 |
| Altri autori (Persone) |
ChadwickDerek
CardewGail |
| Collana | Novartis Foundation Symposium |
| Soggetto topico |
Genetic regulation
Epigenesis DNA - Methylation |
| ISBN |
1-282-34808-6
9786612348082 0-470-51550-3 0-470-51551-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
EPIGENETICS; Participants; Contents; Introduction; Gene silencing by methyl-CpG- binding proteins; DNAmethylation, nucleosornes and the inheritance okhromatin structure and function; General discussion I; Heritable chromatin states induced by the Polycomb and trithorax group genes; The dynamics of globin gene expression and position effects; Multiple epigenetic events regulate mating-type switching of fission yeast; General discussion I1; Nuclear organization and silencing: trafficking of Sir proteins; Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon
Transgene-promoted epigenetic switches of chalcone synthase activity in petunia plantsGeneral discussion I11; Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns; The host defence function of genomic methylation patterns; Mammalian X chromosome inactivation; Methylation dynamics, epigenetic fidelity and X chromosome structure; General discussion IV; Imprinting and gene silencing in mice and DrosophiZa; Making sense of imprinting the mouse and human IGF2R loci; Imprinted genes in the Prader-Willi deletion; Final general discussion SummaryIndex of contributors; Subject index |
| Record Nr. | UNINA-9910829987403321 |
| Chichester, [England] : , : John Wiley & Sons, , 1998 | ||
| Lo trovi qui: Univ. Federico II | ||
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Epigenetics
| Epigenetics |
| Pubbl/distr/stampa | Georgetown, Tex., : Landes Bioscience |
| Disciplina | 576.5 |
| Soggetto topico |
Epigenesis
DNA - Methylation Epigenesis, Genetic DNA Methylation Epigenetica |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1559-2308 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996214997203316 |
| Georgetown, Tex., : Landes Bioscience | ||
| Lo trovi qui: Univ. di Salerno | ||
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Epigenetics
| Epigenetics |
| Pubbl/distr/stampa | Georgetown, Tex., : Landes Bioscience |
| Disciplina | 576.5 |
| Soggetto topico |
Epigenesis
DNA - Methylation Epigenesis, Genetic DNA Methylation Epigenetica |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 1559-2308 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910147179503321 |
| Georgetown, Tex., : Landes Bioscience | ||
| Lo trovi qui: Univ. Federico II | ||
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Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
| Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler |
| Autore | Doerfler Walter <1933-> |
| Pubbl/distr/stampa | Weinheim ; ; New York, : Wiley-VCH, c2000 |
| Descrizione fisica | 1 online resource (197 p.) |
| Disciplina |
572.819
572.8619 |
| Soggetto topico |
Genetic transformation
Mammals - Genetics Adenoviruses DNA DNA - Methylation |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-281-76415-9
9786611764159 3-527-61346-3 3-527-61347-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters 4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis 5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes 7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals 8.6 Critical evaluation of the results obtained with transgenic animals |
| Record Nr. | UNINA-9910144734503321 |
Doerfler Walter <1933->
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| Weinheim ; ; New York, : Wiley-VCH, c2000 | ||
| Lo trovi qui: Univ. Federico II | ||
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