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Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso
Biomolecular therapeutics for human cancer / / edited by Antonio Giordano, Marcella Macaluso
Edizione [1st ed.]
Pubbl/distr/stampa Hoboken, N.J., : Wiley-Blackwell, c2011
Descrizione fisica 1 online resource (420 p.)
Disciplina 616.99/4042
Altri autori (Persone) GiordanoAntonio
MacalusoMarcella
Collana Cancer epigenetics
Soggetto topico Cancer - Genetic aspects
Cancer - Treatment
Epigenesis
DNA - Methylation
ISBN 9786613110688
9781283110686
1283110687
9781118005736
1118005732
9781118005743
1118005740
9781118005729
1118005724
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto (Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? / by Micaela Montanari, Antonio Giordano, Marcella Cintorino and Marcella Macaluso -- Section II: Epigenetics and Cell Development, Senescence and Differentiation -- Epigenetic in skeletal muscle Development? / by Cristina Giacinti and Antonio Giordano -- Epigenetic control in cellular senescence? / by Heike Helmbold, Wolfgang Deppert, and Wolfgang Bohn -- Epigenetic modulation in cell development and differentiation? / by Mario Mancino, Claudia Esposito, Raffaella Pasquale, Immacolata Vocca and Francesca Pentimalli -- Section III: Epigenetics and Gene Transcription -- Epigenetic control of gene transcription? / by Christian Bronner, Mayada Achour, Thierry Chataigneau and Valerie B. Schini-Kerth -- Epigenetics, microRNAs and cancer: an update? / by Giuseppe Russo1, Andrew Puca, Francesco Masulli, Stefano Rovetta, Letizia Cito, Debora Muresu, Flavio Rizzolio and Antonio Giordano -- Section IV: Epigenetics and Cancer -- Epigenetics and Cancer? by Michael J. Powell, Vladimir M. Popov, Xiang Wang, Steven B. McMahon, Alexander Mazo, and Richard G. Pestell --
The MBD4/MED1 Protein in DNA Repair, DNA Demethylation, Disease and Cancer? / Serena Buontempo, Mara Sannai and Alfonso Bellacosa -- Epigenetics in pediatric cancers? by Roberta Ciarapica, Lavinia Raimondi, Federica Verginelli, Rossella Rota -- Epigenetic mechanisms in cancer formation and progression? by Elisabetta Fratta, Luca Sigalotti, Alessia Covre, Giulia Parisi, Riccardo Danielli, Hugues Jean Marie Nicolay, Sandra Coral, Michele Maio -- Section V: Epigenetics and Anticancer Drug Development and Therapy -- Recent advances in the field of stem cell research: towards the definition of the epigenetic and genetic codes of pluripotency? / by Gaetano Romano -- Potential of Heat Shock Protein Targeting for Human Therapy? / by Laszlo Otvos, Jr -- Advancements in Stem Cell Therapy & Research? /by Andrew Puca and Antonio Giordano.
Record Nr. UNINA-9910140979703321
Hoboken, N.J., : Wiley-Blackwell, c2011
Materiale a stampa
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DNA methylation : patterns, functions and roles in disease / / Kathleen Holland, editor
DNA methylation : patterns, functions and roles in disease / / Kathleen Holland, editor
Pubbl/distr/stampa Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016]
Descrizione fisica 1 online resource (225 pages) : illustrations
Disciplina 572.8/6
Collana Genetics - research and issues
Soggetto topico DNA - Methylation
ISBN 1-5361-0261-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910148697203321
Hauppauge, New York : , : Nova Science Publisher's, Incorporated, , [2016]
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DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
Autore Vaniushin B. F
Pubbl/distr/stampa New York, : Nova Biomedical Books, c2009
Descrizione fisica 1 online resource (164 p.)
Disciplina 572.8/2
Altri autori (Persone) AshapkinVasili V
Soggetto topico Plant biochemical genetics
DNA - Methylation
Soggetto genere / forma Electronic books.
ISBN 1-60876-414-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""DNA METHYLATION IN PLANTS""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""INTRODUCTION""; ""IS THE CYTOSINE DNA METHYLATION AT ALL IMPORTANT?""; ""ARE TRANSPOSABLE SEQUENCES SILENCED BY CYTOSINE METHYLATION?""; ""ARE MULTICOPY GENES SILENCED BY CYTOSINE METHYLATION?""; ""IS GENE SILENCING ALWAYS ASSOCIATED WITH THEIR METHYLATION?""; ""ARE THE EPIGENETIC CHANGES INHERITABLE?""; ""CYTOSINE DNA-METHYLTRANSFERASES: HOW MANY OF THEM ARE NEEDED?""; ""1. MET1 IS A MAJOR CPG-SPECIFIC MAINTENANCE PLANT DNA-METHYLTRANSFERASE""
""2. CHROMOMETHYLASE IS A PLANT SPECIFIC DNA-METHYLTRANSFERASE""""3. DRM ARE THE PLANT DE NOVO DNA-METHYLTRANSFERASES""; ""ARE THERE SIGNALS FOR THE DE NOVO DNA METHYLATION?""; ""IS DNA METHYLATION ITSELF REGULATED BY DNA METHYLATION?""; ""H3 HISTONE METHYLATION OR HOW DNA METHYLATION PATTERNS ARE ESTABLISHED AND MAINTAINED?""; ""IS DSRNA AN ANOTHER WAY OF ESTABLISHING DNA METHYLATION PATTERNS?""; ""ADENINE DNA METHYLATION""; ""N6-METHYLADENINE IN DNA OF EUKARYOTES""; ""ADENINE DNA-METHYLTRANSFERASES""; ""PUTATIVE ROLE OF ADENINE DNA METHYLATION IN PLANTS""; ""CONCLUSION""
""ACKNOWLEDGEMENTS""""REFERENCES""; ""INDEX""
Record Nr. UNINA-9910455191603321
Vaniushin B. F  
New York, : Nova Biomedical Books, c2009
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DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
DNA methylation in plants [[electronic resource] /] / Boris F. Vanyushin, Vasili V. Ashapkin
Autore Vaniushin B. F
Pubbl/distr/stampa New York, : Nova Biomedical Books, c2009
Descrizione fisica 1 online resource (164 p.)
Disciplina 572.8/2
Altri autori (Persone) AshapkinVasili V
Soggetto topico Plant biochemical genetics
DNA - Methylation
ISBN 1-60876-414-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto ""DNA METHYLATION IN PLANTS""; ""NOTICE TO THE READER""; ""CONTENTS""; ""PREFACE""; ""INTRODUCTION""; ""IS THE CYTOSINE DNA METHYLATION AT ALL IMPORTANT?""; ""ARE TRANSPOSABLE SEQUENCES SILENCED BY CYTOSINE METHYLATION?""; ""ARE MULTICOPY GENES SILENCED BY CYTOSINE METHYLATION?""; ""IS GENE SILENCING ALWAYS ASSOCIATED WITH THEIR METHYLATION?""; ""ARE THE EPIGENETIC CHANGES INHERITABLE?""; ""CYTOSINE DNA-METHYLTRANSFERASES: HOW MANY OF THEM ARE NEEDED?""; ""1. MET1 IS A MAJOR CPG-SPECIFIC MAINTENANCE PLANT DNA-METHYLTRANSFERASE""
""2. CHROMOMETHYLASE IS A PLANT SPECIFIC DNA-METHYLTRANSFERASE""""3. DRM ARE THE PLANT DE NOVO DNA-METHYLTRANSFERASES""; ""ARE THERE SIGNALS FOR THE DE NOVO DNA METHYLATION?""; ""IS DNA METHYLATION ITSELF REGULATED BY DNA METHYLATION?""; ""H3 HISTONE METHYLATION OR HOW DNA METHYLATION PATTERNS ARE ESTABLISHED AND MAINTAINED?""; ""IS DSRNA AN ANOTHER WAY OF ESTABLISHING DNA METHYLATION PATTERNS?""; ""ADENINE DNA METHYLATION""; ""N6-METHYLADENINE IN DNA OF EUKARYOTES""; ""ADENINE DNA-METHYLTRANSFERASES""; ""PUTATIVE ROLE OF ADENINE DNA METHYLATION IN PLANTS""; ""CONCLUSION""
""ACKNOWLEDGEMENTS""""REFERENCES""; ""INDEX""
Record Nr. UNINA-9910778005803321
Vaniushin B. F  
New York, : Nova Biomedical Books, c2009
Materiale a stampa
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DNA Methylation Mechanism / / edited by Metin Budak and Mustafa Yıldız
DNA Methylation Mechanism / / edited by Metin Budak and Mustafa Yıldız
Pubbl/distr/stampa London, United Kingdom : , : IntechOpen, , 2020
Descrizione fisica 1 online resource (161 pages) : illustrations (some color)
Disciplina 574.873282
Collana Biochemistry
Soggetto topico DNA - Methylation
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910688589503321
London, United Kingdom : , : IntechOpen, , 2020
Materiale a stampa
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Epigenetics
Epigenetics
Pubbl/distr/stampa Chichester, [England] : , : John Wiley & Sons, , 1998
Descrizione fisica 1 online resource (320 p.)
Disciplina 572.8
572.865
Altri autori (Persone) ChadwickDerek
CardewGail
Collana Novartis Foundation Symposium
Soggetto topico Genetic regulation
Epigenesis
DNA - Methylation
Soggetto genere / forma Electronic books.
ISBN 1-282-34808-6
9786612348082
0-470-51550-3
0-470-51551-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto EPIGENETICS; Participants; Contents; Introduction; Gene silencing by methyl-CpG- binding proteins; DNAmethylation, nucleosornes and the inheritance okhromatin structure and function; General discussion I; Heritable chromatin states induced by the Polycomb and trithorax group genes; The dynamics of globin gene expression and position effects; Multiple epigenetic events regulate mating-type switching of fission yeast; General discussion I1; Nuclear organization and silencing: trafficking of Sir proteins; Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon
Transgene-promoted epigenetic switches of chalcone synthase activity in petunia plantsGeneral discussion I11; Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns; The host defence function of genomic methylation patterns; Mammalian X chromosome inactivation; Methylation dynamics, epigenetic fidelity and X chromosome structure; General discussion IV; Imprinting and gene silencing in mice and DrosophiZa; Making sense of imprinting the mouse and human IGF2R loci; Imprinted genes in the Prader-Willi deletion; Final general discussion
SummaryIndex of contributors; Subject index
Record Nr. UNINA-9910144559903321
Chichester, [England] : , : John Wiley & Sons, , 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Epigenetics
Epigenetics
Pubbl/distr/stampa Chichester, [England] : , : John Wiley & Sons, , 1998
Descrizione fisica 1 online resource (320 p.)
Disciplina 572.8
572.865
Altri autori (Persone) ChadwickDerek
CardewGail
Collana Novartis Foundation Symposium
Soggetto topico Genetic regulation
Epigenesis
DNA - Methylation
ISBN 1-282-34808-6
9786612348082
0-470-51550-3
0-470-51551-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto EPIGENETICS; Participants; Contents; Introduction; Gene silencing by methyl-CpG- binding proteins; DNAmethylation, nucleosornes and the inheritance okhromatin structure and function; General discussion I; Heritable chromatin states induced by the Polycomb and trithorax group genes; The dynamics of globin gene expression and position effects; Multiple epigenetic events regulate mating-type switching of fission yeast; General discussion I1; Nuclear organization and silencing: trafficking of Sir proteins; Epigenetic mechanisms in the regulation of the maize Suppressor-mutator transposon
Transgene-promoted epigenetic switches of chalcone synthase activity in petunia plantsGeneral discussion I11; Gene silencing in plants: relevance for genome evolution and the acquisition of genomic methylation patterns; The host defence function of genomic methylation patterns; Mammalian X chromosome inactivation; Methylation dynamics, epigenetic fidelity and X chromosome structure; General discussion IV; Imprinting and gene silencing in mice and DrosophiZa; Making sense of imprinting the mouse and human IGF2R loci; Imprinted genes in the Prader-Willi deletion; Final general discussion
SummaryIndex of contributors; Subject index
Record Nr. UNINA-9910829987403321
Chichester, [England] : , : John Wiley & Sons, , 1998
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Epigenetics
Epigenetics
Pubbl/distr/stampa Georgetown, Tex., : Landes Bioscience
Disciplina 576.5
Soggetto topico Epigenesis
DNA - Methylation
Epigenesis, Genetic
DNA Methylation
Epigenetica
Soggetto genere / forma Periodical
Periodicals.
ISSN 1559-2308
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNISA-996214997203316
Georgetown, Tex., : Landes Bioscience
Materiale a stampa
Lo trovi qui: Univ. di Salerno
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Epigenetics
Epigenetics
Pubbl/distr/stampa Georgetown, Tex., : Landes Bioscience
Disciplina 576.5
Soggetto topico Epigenesis
DNA - Methylation
Epigenesis, Genetic
DNA Methylation
Epigenetica
Soggetto genere / forma Periodical
Periodicals.
ISSN 1559-2308
Formato Materiale a stampa
Livello bibliografico Periodico
Lingua di pubblicazione eng
Record Nr. UNINA-9910147179503321
Georgetown, Tex., : Landes Bioscience
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
Foreign DNA in mammalian systems [[electronic resource] /] / Walter Doerfler
Autore Doerfler Walter <1933->
Pubbl/distr/stampa Weinheim ; ; New York, : Wiley-VCH, c2000
Descrizione fisica 1 online resource (197 p.)
Disciplina 572.819
572.8619
Soggetto topico Genetic transformation
Mammals - Genetics
Adenoviruses
DNA
DNA - Methylation
Soggetto genere / forma Electronic books.
ISBN 1-281-76415-9
9786611764159
3-527-61346-3
3-527-61347-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Foreign DNA in Mammalian Systems; Preface; Contents; 1 Introduction; 1.1 Further reading; 2 ForeignDNA; 2.1 Foreign DNA in the environment; 2.2 Uptake and modes of persistence of foreign DNA in mammalian cells; 2.3 Further reading; 3 Methods to detect integrated foreign DNA; 3.1 Parameters of foreign DNA integration; 3.2 The fluorescent in situ hybridization method; 3.3 Detection of foreign DNA by Southern DNA ti DNA hybridization; 3.4 Detection of foreign DNA sequences by the pol reaction (PCR); 3.5 Recloning of junction fragments and the detern nucleotide sequences
3.6 Equilibirum sedimentation in alkaline CsCl gral DNA hybridization3.7 Further reading; 4 The adenovirus paradigm; 4.1 An introduction to the adenovirus system; 4.1.1 Clinical background; 4.1.2 Virion structure; 4.1.3 Classification; 4.1.4 Multiplication during productive infection; 4.1.5 Abortive infection; 4.2 An example: Ad12 DNA integration in the Ad12 hamster cell line T637; 4.3 The state of the viral DNA in different cell systems; 4.3.1 Productive infection; 4.3.2 Abortive infection; 4.3.3 Transformation of cells in culture; 4.3.4 Tumor induction by Ad12 in newborn hamsters
4.3.5 Tumor cells in culture4.3.6 Loss of previously integrated Ad12 DNA sequences; 4.4 Adenovirus infection, DNA transfection or DNA microinjection; 4.5 Integration of adenovirus DNA in human cells - significance human somatic gene therapy; 4.6 Studies on integrative recombination of adenovirus DNA in a cell-free system; 4.7 Further reading; 5 Conclusions derived from a survey of junction sites; 5.1 On the characteristics of junction sequences; 5.2 Persistence of integrated foreign DNA - a novel functional type of insertional mutagenesis
5.3 Adenovirus DNA: chromosomal association - covalent genc integration5.4 Further reading; 6 Adenovirus-induced tumor cells and revertants; 6.1 Clonal origin of Ad12-induced tumors; 6.2 Stability - instability; 6.2.1 Hit-and-run mechanism of viral oncogenesis?; 6.2.2 General implications of a hit-and-run mechanism; 6.3 Further reading; 7 Comparisons with other viral systems; 7.1 Integration of viral DNA; 7.2 Transcription of integrated viral genomes; Color plates; 7.3 Virus-induced tumors; 7.4 Replication and integration of the retroviral genome; 7.5 Endogenous retroviral genomes
7.6 The viral archetype: integration of bacteriophage λ DNA7.6.1 The most important regulatory functions in the phage λ genome; 7.6.2 Control of transcription at the right operator OR of phage λ DNA; 7.6.3 A closer look at the integration and excision of the bacteriophage λ genome; 7.7 Further reading; 8 Non-viral systems; 8.1 Exchange of genetic information with extracellular DNA in pneumococci; 8.2 IS elements and transposons; 8.3 Thoughts on the mechanism of foreign DNA integration; 8.4 Expression of integrated foreign DNA; 8.5 Fixation of foreign DNA in transgenic animals
8.6 Critical evaluation of the results obtained with transgenic animals
Record Nr. UNINA-9910144734503321
Doerfler Walter <1933->  
Weinheim ; ; New York, : Wiley-VCH, c2000
Materiale a stampa
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