The Blood Brain Barrier and Inflammation / / edited by Ruth Lyck, Gaby Enzmann |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (VI, 286 p. 32 illus., 24 illus. in color.) |
Disciplina | 616.079 |
Collana | Progress in Inflammation Research |
Soggetto topico |
Immunology
Neurosciences Cell membranes Infectious diseases Cytokines Growth factors Membrane Biology Infectious Diseases Cytokines and Growth Factors |
ISBN | 3-319-45514-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | General Introduction to Barrier Mechanisms in the Central Nervous System -- Topological Aspects of the Blood-brain and Blood cerebrospinal Fluid Barriers and their Relevance in Inflammation Research -- The Contribution of the Extracellular Matrix to the BBB in Steady State and Inflammatory Conditions -- Pathophysiology of the Bloodbrain Barrier in Neuroinflammatory Diseases -- Leakage at Blood-neural Barriers -- Blood-Brain Barrier Transporters and Neuroinflammation: Partners in Neuroprotection and in Pathology -- MicroRNAs in Brain Endothelium and Inflammation -- Blood-Brain Barrier Dysfunction during Central Nervous System Autoimmune Diseases -- Pathways Across the Blood Brain Barrier -- Neuroinflammation in Bacterial Meningitis -- Blood Vessels in the Brain: a Signaling Hub in Brain Tumor Inflammation. |
Record Nr. | UNINA-9910254467803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Bone Morphogenetic Proteins: Systems Biology Regulators / / edited by Slobodan Vukicevic, Kuber T. Sampath |
Edizione | [1st ed. 2017.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 |
Descrizione fisica | 1 online resource (XII, 445 p. 43 illus., 32 illus. in color.) |
Disciplina | 616.079 |
Collana | Progress in Inflammation Research |
Soggetto topico |
Immunology
Cell biology Cytokines Growth factors Proteins Systems biology Cell Biology Cytokines and Growth Factors Protein Science Systems Biology |
ISBN | 3-319-47507-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Introduction -- BMPs: Historic and Future Perspectives -- BMP – Biology -- BMPs in Development -- BMP signaling -- BMP Antagonists - Biology -- BMP and BMP Antagonists - Structure and Function -- BMPs in Orthopaedic Medicine: Promises and Challenges -- BMP6 and Bone Repair -- BMPs in Dental Medicine: Promises and Challenges -- BMPs in Spine -- BMPs in Articular Joints -- BMP Signaling & FOP -- BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases -- BMPs in Inflammation -- BMPs and Angiogenesis -- BMP Signaling in Iron Homeostasis -- BMP Signaling in Pulmonary Arterial Hypertension -- BMP Signaling and Cancer -- BMP Biology in Rare Diseases. |
Record Nr. | UNINA-9910254481703321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017 | ||
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Clinical Medicine Research / / edited by Mieczyslaw Pokorski |
Edizione | [1st ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (vi, 138 pages) : illustrations |
Disciplina | 616.0072 |
Collana | Clinical and Experimental Biomedicine |
Soggetto topico |
Neurochemistry
Cancer research Physiotherapy Cytokines Growth factors Cancer Research Cytokines and Growth Factors |
ISBN | 3-030-04837-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Bioprogressive Paradigm in Physiotherapeutic and Antiaging Strategies: a Review -- Influence of Proprioceptive Neuromuscular Facilitation on Lung Function in Patients after Coronary Artery Bypass Graft Surgery -- Remote Ischemic Preconditioning in Renal Protection During Elective Percutaneous Coronary Intervention -- Prognostic Impact of Extracapsular Lymph Node Invasion on Survival in Non-Small-cell Lung Cancer: a Systematic Review and Meta-Analysis -- Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression -- Cognitive Predictors of Cortical Thickness in Healthy Aging -- Osteoprotegerin, a Receptor Activator of Nuclear Factor kappa B Ligand, and Growth Hormone/Insulin-like Growth Factor-1 Axis in Children with Growth Hormone Deficiency -- Inhibition of Cross-Reactive Carbohydrate Determinants in Allergy Diagnostics -- Effects of Reduced Glutathione on Hydrolytic Enzyme Activity in the Mouse Hepatocytes -- Adaptation to Occupational Exposure to Moderate Endotoxin Concentrations: a Study in Sewage Treatment Plants in Germany -- Effects of Low Level-Laser Therapy in Autism Spectrum Disorder -- Epidemiology of Granulomatosis with Polyangiitis in Poland, 2011–2015. . |
Record Nr. | UNINA-9910298394903321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
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Cytokine Frontiers : Regulation of Immune Responses in Health and Disease / / edited by Takayuki Yoshimoto, Tomohiro Yoshimoto |
Edizione | [1st ed. 2014.] |
Pubbl/distr/stampa | Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014 |
Descrizione fisica | 1 online resource (398 p.) |
Disciplina | 616.079 |
Soggetto topico |
Immunology
Cytokines Growth factors Cell biology Cytokines and Growth Factors Cell Biology |
ISBN | 4-431-54442-9 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I Cytokines in Inflammatory Disorders -- 1 The Interleukin-1 Family2 IL-6 and Inflammatory Diseases -- 3 The Roles of IL-17A and IL-17F in Infection and Inflammatory Disorders -- 4 IL-18 -- 5 Interleukin-21: A Pleiotropic Mediator of Immunity and Inflammation with Broad Therapeutic Potential -- 6 Interleukin-22: A Bridge Between Epithelial Innate Host Defense and Immune Cells -- 7 IL-23 in Health and Disease -- 8 IL-36: An Epithelial Cytokine Important in Psoriasis -- 9 Anti-TNF Therapy: 20 Years from Our First Therapeutic Adventure -- Part II Cytokines in Allergic Disorders -- 10 Interleukin-25: A Key Initiator of Type 2 Immune Responses -- 11 Interleukin-33: A Multifunctional Alarmin that Promotes Both Health and Disease -- 12 Thymic Stromal Lymphopoietin (TSLP) -- Part III Cytokines in Immunological Tolerance and Anti-inflammation -- 13 Interleukin-10: Cytokines in Anti-inflammation and Tolerance -- 14 Interleukin-27: Regulation of Immune Responses and Disease Development by a Pleiotropic Cytokine with Pro- and Anti-inflammatory Properties -- 15 Interleukin-35: A Novel Mediator of Peripheral Tolerance -- Index. . |
Record Nr. | UNINA-9910298314103321 |
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014 | ||
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Lo trovi qui: Univ. Federico II | ||
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Cytokine Storm Syndrome / / edited by Randy Q. Cron, Edward M. Behrens |
Edizione | [1st ed. 2019.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
Descrizione fisica | 1 online resource (XXI, 617 p. 31 illus., 25 illus. in color.) |
Disciplina |
616.079
616.97 |
Soggetto topico |
Immunology
Cytogenetics Infectious diseases Cytokines Growth factors Infectious Diseases Cytokines and Growth Factors |
ISBN | 3-030-22094-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I: Background -- 1. Cytokines in Cytokine Storm Syndrome -- 2. History of hemophagocytic lymphohistiocytosis -- 3.The History of Macrophage Activation Syndrome in Autoimmune Diseases -- 4. Clinical Features of Cytokine Storm Syndrome -- 5. Laboratory Features and Pathology of the Cytokine Storm Syndromes -- 6. Criteria for Cytokine Storm Syndromes -- Part II: Genetics of Cytokine Storm Syndromes -- 7.Genetics of Acquired Cytokine Storm Syndromes -- 8. Genetics of Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis -- Part III: Immunology of Cytokine Storm Syndromes -- 9. CD8+ T cell biology in cytokine storm syndromes -- 10. Immunology of Cytokine Storm Syndromes: Natural Killer Cells -- 11. Myeloid cells in the immunopathogenesis of cytokine storm syndromes -- 12. Cytokines in Cytokine Storm Syndrome -- 13. Primary Immunodeficiencies and Cytokine Storm Syndromes -- Part IV: Infectious Triggers of Cytokine Storm Syndromes -- 14. Infectious Triggers of Cytokine Storm Syndromes: Herpes Virus Family (non-EBV) -- 15. Cytokine Storm Syndromes Associated with Epstein Barr Virus -- 16. Cytokine Storm Syndrome Associated with Hemorrhagic Fever and Other Viruses -- 17. Cytokine Storm Syndrome as a manifestation of Primary HIV Infection -- 18. Bacteria-Associated Cytokine Storm Syndrome -- 19. Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome -- 20. Parasitic and Fungal Triggers -- Part V: Rheumatic Triggers of Cytokine Storm Syndromes -- 21. Cytokine Storm Syndrome associated with Systemic Juvenile Idiopathic Arthritis -- 22. Systemic Lupus Erythematosus and Cytokine Storm -- 23. Kawasaki Disease -- 24. The Intersections of Autoinflammation and Cytokine Storm -- 25. Macrophage Activation Syndrome in the Setting of Rheumatic Diseases -- Part VI: Other Triggers of Cytokine Storm Syndromes -- 26. Hemophagocytic lymphohistiocytosis in the context of hematological malignancies and solid tumors -- 27. Cytokine Storm and Sepsis induced Multiple Organ Dysfunction Syndrome -- Part VII: Murine Models of Cytokine Storm Syndrome -- 28. Murine Models of Familial Cytokine Storm Syndromes -- 29. Murine Models of Secondary Cytokine Storm Syndromes -- Part VIII: Therapy of Cytokine Storm Syndromes -- 30. Etoposide Therapy of Cytokine Storm Syndromes -- 31. IL-1 Family Blockade -- 32. IL-6 Blockade -- 33. Alternative Therapies for Cytokine Storm Syndromes -- 34. Salvage Therapy and Allogeneic Hematopoietic Cell Transplantation for the Severe Cytokine Storm Syndrome of Hemophagocytic Lymphohistiocytosis. |
Record Nr. | UNINA-9910349444603321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
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Lo trovi qui: Univ. Federico II | ||
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Encyclopedia of Signaling Molecules / / edited by Sangdun Choi |
Edizione | [2nd ed. 2018.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 |
Descrizione fisica | 1 online resource (1893 illus., 1746 illus. in color. eReference.) |
Disciplina | 572.69603 |
Soggetto topico |
Medical genetics
Molecular biology Cytokines Growth factors Cell biology Proteins Bioinformatics Gene Function Molecular Medicine Cytokines and Growth Factors Cell Biology Protein-Ligand Interactions |
ISBN | 3-319-67199-5 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | From the contents 14-3-3 -- 3-Phosphoinositide-Dependent Kinase 1 (PDK1) -- 5-HTT -- 5-Hydroxytryptamine Receptor 2C -- 5-Hydroxytryptamine Receptor 6 -- A-Kinase Anchoring Protein (AKAP) -- A-RAF -- ABCA Transporters -- ABCA3 -- ACAP1 -- Acetylcholine (Nicotinic) Receptor -- Acetylcholinesterase -- ACK1 -- ACSL4 -- ACT -- Actinin Family -- ADAMTS13 -- ADAP -- ADAP1 -- ADAP2 -- ADCY9 (Adenylyl Cyclase 9) -- Adenomatous Polyposis Coli -- Adenylyl Cyclase -- ADGRB3 -- ADGRG2 -- Adiponectin -- ADP-Ribosylation Factor-6 (ARF6) -- AGAP1 -- AIFM1 -- AIRE -- AKT -- Alpha-1-Syntrophin -- Alpha-2A Adrenergic Receptor -- ALS2 -- AMP-Activated Protein Kinase (AMPK) -- Androgen Receptor (AR) -- ANT -- AP-4 -- APO2L/TRAIL -- Apoptosis Regulator BAX -- Apoptosis-inducing factor 1, mitochondrial -- App -- Aquaporin -- ARAP3 -- ARF1 -- Arl8b -- Aryl Hydrocarbon Receptor -- Ataxia Telangiectasia and Rad3-Related (ATR) -- ATF2 -- ATP-Binding Cassette Subfamily A Member 2 -- Aurora Kinases -- Axin -- AXL -- B Lymphocyte Antigen CD19. |
Record Nr. | UNINA-9910298435803321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018 | ||
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Encyclopedia of Signaling Molecules [[electronic resource] /] / edited by Sangdun Choi |
Edizione | [1st ed. 2012.] |
Pubbl/distr/stampa | New York, NY : , : Springer New York : , : Imprint : Springer, , 2012 |
Descrizione fisica | 1 online resource (300 illus., 100 illus. in color. eReference.) |
Disciplina | 611.01816 |
Collana | Springer reference |
Soggetto topico |
Medical genetics
Medicine Cytokines Cytology RNA-ligand interactions Bioinformatics Gene Function Molecular Medicine Cytokines and Growth Factors Cell Biology Protein-Ligand Interactions |
ISBN | 1-4419-0461-1 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | 5-Hydrocytryptamine receptor 3a -- 5-Hydroxytryptamine receptor 2B -- 5-Hydroxytryptamine receptor 2C -- A-Raf -- ABCA -- Ack1 -- ADAP -- Adap1 -- Adenylyl cyclase -- Adenylyl cyclase type 9 -- Adhesion-GPCRs -- ADP-ribosylation factor domain protein 1 -- Ags (Activators of G-protein signaling) -- Aif -- AKAP -- Androgen receptor -- Angiotensin II receptor 2 -- Ant -- AP-3 -- AP-4 -- Apo2L (TRAIL) -- Arap3 -- Arf-like protein 8b -- Arfgap1 -- Arfrp1 -- ATF3 -- Aurora kinase -- Bcl2 family -- Beta-Catenin -- Bradykinin receptor -- Btg/Tob -- c-Myb -- Cadherin -- Calcium channel, voltage-dependent -- Calpain -- Carma1 -- Casein kinase II -- Caspase -- Cbln1 -- CCL3 [chemokine (C-C motif) ligand 3] -- CCL4 [chemokine (C-C motif) ligand 4] -- CCL5 [chemokine (C-C motif) ligand 5] -- CCN -- CCTa -- CD160 -- CD3 -- CD3 zeta -- CD38 -- CD40 -- CD43 -- CD45 -- CD47 -- CD53 -- CD72 -- CD81 -- CD91 -- Cdc7 -- CDK11 -- Ceacam -- Chemokine ligand CX3CL1 -- Chemokine receptor CCR1 -- Cholecystokinin type B receptor (CCK type B receptor) -- Cholecystokinin-1 receptor -- CKIP-1 -- CLEC-1 -- CLEC-2 -- CLEC4E -- CLEC5A -- Clk -- Copine -- CREB -- Csk -- Csk homologous kinase -- CXCL10 [Chemokine (C-X-C motif) ligand 10 or IP-10] -- Cyclin A -- Dap kinase -- Darpp -- Dbf4 -- Dect in-1 -- delta glutamate receptor -- DHHC -- DLK (dual leucine zipper-bearing kinase) -- Dock2 -- Drak2 -- Ect2 (epithelial cell transforming 2 oncogene) -- eIF5 -- eIF6 -- Endo180 -- Endothelin A receptor -- Eph receptor -- EphA3 -- Eps8 (epidermal growth factor receptor pathway substrate 8) -- Erk1/Erk2 -- Erk3/Erk4 -- ERK5/MEK5 -- Estrogen receptor -- Fbln -- FGF (fibroblast growth factor) -- Fgr -- Fhit -- Flotillin 1 -- Flotillin 2 -- Fn14 -- Follicle stimulating hormone receptor -- Formyl peptide receptor -- FOXO1 -- FPR2/ALX -- Frabin -- Frs2 -- FZD (frizzled homolog) -- G alpha i-class G protein alpha subunits -- G protein alpha 12 -- G protein alpha q -- G protein alpha transducin -- G protein beta/gamma -- Gab1 -- Gab2 -- GABA A receptor -- Gadd45 -- Galanin receptor -- Gat (GABA transporter) -- GATA-3 (GATA binding protein 3) -- GCAP (guanylyl cyclase activating protein) -- Geft -- Glucose dependent insulinotropic polypeptide receptor -- Glutamate receptors -- Gpr84 -- Grp94 (HSP90B1) -- Gsk (glycogen synthase kinase) -- GST (glutathione S-transferase) -- Guanylate cyclase -- Guanylyl cyclase C -- Guanylyl cyclase receptors -- HB-EGF (heparin-binding EGF-like growth factor) -- Hipk2 -- Hippocalcin -- hnRNP (heterogeneous nuclear ribonucleoprotein) -- Homer -- Hpk1 -- IAP -- Icmt (Isoprenylcysteine carboxyl methyltransferase) -- Id4 (Inhibitor of DNA binding 4) -- IFN gamma -- IGF1R (insulin-like growth factor 1 receptor) -- IL6 -- IL7 -- Inositol 1,4,5-triphosphate-associated cGMP kinase substrate -- Integrin alpha 1 -- Integrin alpha 11 -- Integrin alpha 2 -- Integrin alpha 4 -- Integrin alpha E -- Integrin alpha V -- IP3 receptor -- IRF5 -- IRG (immunity-related GTPase) -- Itpk1 (inositol 1,3,4-triphosphate 5/6 kinase) -- Itsn -- Laforin -- Lat (linker for activation of T cells) -- LCoR -- LIMK -- Lysyl oxidase -- MAIL (IkBz) -- Malt1 (mucosa associated lymphoid tissue lymphoma translocation gene 1) -- MAP kinases (comprising 14 genes: Erk1, Erk2, Erk3, Erk4, Erk5, Erk7, Jnks (3 isoforms), p38 (4 isoforms) and Nlk) -- Mapkap kinase 2/3 (MK2/3) -- Mapkap kinase 5 (MK5)(PRAK) -- Mark (MAP/microtubule affinity-regulating kinase) -- Mek -- Mek3 -- Mk-styx -- MKK6 -- Mlk (mixed lineage kinase) -- MLTK -- MORF/MOZ lysine acetyltranferase -- Mps1 -- Msk1 -- mTOR -- Mtus1 -- Myc -- MyD88 (myeloid differentiation primary response gene 88) -- MYLK (Myosin linght chain kinase) -- Myosin I (Myo1) -- Myosin III -- Myosin X -- N-WASP -- Ncam (neural cell adhesion molecule) -- Nek (never in mitosis gene a-related expressed kinase) -- Net1 (neuroepithelial cell transforming gene 1 protein) -- Neurotensin receptor -- NF-kB family -- NFAT -- Nherf -- NK receptor -- NKG2D -- NKp46 -- NMT (N-myristoyltransferase) -- Notch -- Nrf2 (NF-E2-related factor2) -- nrip1(Nuclear Receptor-Interacting Protein 1) -- NTPDase family -- Nucleotide receptor P2x -- Nucleotide receptor P2y -- Olfactory receptor -- Opioid receptor -- P-Rex -- p130Cas -- P2Y14 receptor -- P38 MAPK -- P53 -- Pak2 -- PCAF lysine acetyltransferase -- Pea15 -- Phlda1 (T-cell death associated gene)(Pleckstrin homology-like domain, family A, member 1) -- Phosphodiesterase 1 -- Phosphodiesterase 10A -- Phosphodiesterase 4, cAMP specific -- Phosphoinositide 3-kinase -- Phosphoinositide 5-phosphate 4-kinase -- Phospholipase A -- Phospholipase D -- Pim-1 -- Pin1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) -- Pink1 -- PKD -- PKR -- Plasma membrane calcium transporting ATPase -- Plekhg5 -- Polycystin -- PP2C -- Prep -- Prion protein -- Protein farnesyltransferase -- Psgr (prostate specific G-protein coupled receptor) -- PTEN -- PTK6 -- PTPe (RPTPe and cyt-PTPe) -- PTPN3/PTPN4 -- R7BP/R9AP -- Rab18 -- Rab23 -- Rab 7 -- Rab 8 -- Rac -- Raf1 -- Ramp -- Ran -- RANKL and RANK -- Rap GEF family -- Ras (H-, K-, N-Ras) -- RASA1 -- Rasgrf (RAS protein-specific guanine nucleotide-releasing factor) -- RasGRP1 -- Rcan1 (regulator of calcineurin) -- Recoverin -- Relaxin family peptide receptor: 1 & 2 -- Relaxin family peptide receptor: 3 & 4 -- Retinoic acid receptor -- RGS family -- Rgs13 -- RhoC -- Rhodopsin kinase -- Ric8 -- Rin (Ras-like protein in neuron) -- RIN family proteins (RIN1, RIN2 and RIN3) -- ROCK kinases -- Rpn8 -- Rpt -- Rrad (Ras-related associated with diabetes) -- Rsk (p90 ribosomal S6 kinase) -- RyR (ryanodine receptor) -- S100 Proteins -- SAMSN1 (SAM domain, SH3 domain and nuclear localization signal) -- SARA -- Sh2d2a (SH2 domain protein 2A) -- SHIP -- SHP-1 -- SKAP-HOM -- Slp (synaptotagmin-like protein) -- SLP-76 (SH2 domain containing leukocyte protein of 76kDa) -- SOCS -- Somatostatin receptor -- Sonic hedgehog -- Sphingosine-1-phosphate -- Src -- Sry -- STAT -- Striatal-Enriched Protein Tyrosine Phosphatase (STEP) -- Sulfiredoxin -- SWI/SNF (SWItch/Sucrose NonFermentable) -- TBCCD1 -- Tead -- The Steroid Receptor Coactivator Family -- Thrombospondin 1 -- TLR adaptor protein -- TLR3 -- TLR4 -- TLR5 -- TLR9 -- TMEM85 (transmembrane protein 85) -- TPD52 (tumor protein D52) -- Tpl2 -- TRAF6 -- TRAIL receptor 1/2 (death receptor 4/5, DR4/5) -- Trb (tribbles) -- Trp (transient receptor potential cation channel) -- Urokinase-type plasminogen activator receptor -- UT (Urea transporter) -- VAMP1/2/3/7 -- Vav Family -- Vitamin D receptor -- VRK1 -- VRK2 -- VRK3 -- WASH -- ZAP-70 -- ZNF202 (zinc finger protein 202; Zfp202) -- ZnT (zinc transporter). |
Record Nr. | UNINA-9910484235003321 |
New York, NY : , : Springer New York : , : Imprint : Springer, , 2012 | ||
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Lo trovi qui: Univ. Federico II | ||
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Endocannabinoids / / edited by Roger G. Pertwee |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (477 p.) |
Disciplina | 615.7827 |
Collana | Handbook of Experimental Pharmacology |
Soggetto topico |
Pharmacology
Cell biology Neurosciences Psychopharmacology Immunology Cytokines Growth factors Pharmacology/Toxicology Cell Biology Cytokines and Growth Factors |
ISBN | 3-319-20825-X |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto |
Preface; The Endocannabinoid System: A Look Back and Ahead; Contents; Endocannabinoids and Their Pharmacological Actions; 1 Introduction; 2 Evidence That Certain Endogenous Compounds Target Cannabinoid Receptors Orthosterically; 2.1 Evidence from Binding Assays; 2.2 Evidence from Two Functional Bioassays; 2.2.1 [35S]GTPgammaS Binding Assay; 2.2.2 Cyclic AMP Assay; 3 Non-Cannabinoid Receptors and Channels Targeted by Endogenous Cannabinoid Receptor Ligands at Submicromolar Concentrations; 3.1 Non-Cannabinoid G Protein-Coupled Receptors; 3.1.1 GPR55; 3.2 Ligand-Gated Ion Channels
3.2.1 5-HT3 Receptors3.2.2 Nicotinic Acetylcholine Receptors; 3.2.3 Glycine Receptors; 3.2.4 Ionotropic Glutamate NMDA Receptors; 3.3 Transient Receptor Potential Channels; 3.3.1 TRPV1; 3.3.2 TRPM8 Channels; 3.4 Voltage-Gated Calcium Channels; 3.4.1 T-Type Cav3 Calcium Channels; 3.5 Potassium Channels; 3.5.1 ATP-Sensitive Inward Rectifier KATP Channels of the 2TM Domain Family; 3.5.2 Voltage-Gated Kv and KCa Channels of the 6TM Domain Family; 4 Allosteric Endocannabinoids; 5 Conclusions; References; Biosynthesis and Fate of Endocannabinoids 1 Endocannabinoids and Endocannabinoid-Like Compounds2 Biosynthesis of the Endocannabinoids; 3 Uptake of the Endocannabinoids: Proposed Mechanisms; 4 Degradation of the Endocannabinoids; 4.1 FAAH and NAAA; 4.2 MGL, ABHD6 and ABHD12; 5 Conclusions; References; Distribution of the Endocannabinoid System in the Central Nervous System; 1 Introduction; 1.1 Overview; 1.2 Cells Expressing Components of the ECS; 1.3 Subcellular Localization of CB1 Cannabinoid Receptors; 2 Retina; 2.1 Receptors; 2.2 Synthetic Enzymes; 2.3 Degradative Enzymes; 3 Cerebral Cortex; 3.1 Neocortex; 3.1.1 Receptors 3.1.2 Synthetic Enzymes3.1.3 Degradative Enzymes; 3.2 Olfactory Areas (Olfactory Bulb, Piriform Cortex, Associated Regions); 3.2.1 Receptors; 3.2.2 Synthetic Enzymes; 3.2.3 Degradative Enzymes; 3.3 Hippocampal Formation; 3.3.1 Receptors; 3.3.2 Synthetic Enzymes; 3.3.3 Degradative Enzymes; 3.4 Cortical Subplate (Other Amygdala Nuclei); 3.4.1 Receptors; 3.4.2 Synthetic Enzymes; 3.4.3 Degradative Enzymes; 4 Subcortical Nuclei (Striatum, Basal Ganglia); 4.1 Striatum (Dorsal, Caudate); 4.1.1 Receptors; 4.1.2 Synthetic Enzymes; 4.1.3 Degradative Enzymes; 4.2 Striatum (Ventral, Accumbens) 4.2.1 Receptors4.2.2 Synthetic Enzymes; 4.2.3 Degradative Enzymes; 4.3 Striatum Medial (Lateral Septum, Septohippocampal, etc.); 4.3.1 Receptors; 4.3.2 Synthetic Enzymes; 4.3.3 Degradative Enzymes; 4.4 Striatum Caudal (Striatum-like Amygdala Nuclei, Central Amygdala, Bed Nucleus, Medial Amygdala, Etc.); 4.4.1 Receptors; 5 Cerebellum and Associated Nuclei; 5.1 Cerebellar Cortex; 5.1.1 Receptors; 5.1.2 Synthetic Enzymes; 5.1.3 Degradative Enzymes; 5.2 Deep Cerebellar Nuclei (Fastigial, Interpos, Dentate Nucleus); 5.2.1 Receptors; 5.2.2 Synthetic Enzymes; 5.2.3 Degradative Enzymes; 6 Brainstem 6.1 Diencephalon |
Record Nr. | UNINA-9910298267903321 |
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015 | ||
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Extracellular Matrix in Development / / edited by Douglas W. DeSimone, Robert Mecham |
Edizione | [1st ed. 2013.] |
Pubbl/distr/stampa | Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 |
Descrizione fisica | 1 online resource (259 p.) |
Disciplina | 599.03 |
Collana | Biology of Extracellular Matrix |
Soggetto topico |
Developmental biology
Cell biology Regenerative medicine Tissue engineering Cytokines Growth factors Stem cells Developmental Biology Cell Biology Regenerative Medicine/Tissue Engineering Cytokines and Growth Factors Stem Cells |
ISBN | 3-642-35935-3 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I Informational signals in extracellular matrix and matrix influences on cell movement in the developing embryo -- Part II Extracellular matrix-direct morphogenesis, growth factor signaling, and maintenance of the stem cell niche -- Part III Model organisms and the lexicon of developmental signals associated with the extracellular matrix. |
Record Nr. | UNINA-9910739447703321 |
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013 | ||
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Lo trovi qui: Univ. Federico II | ||
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Free Radicals in Human Health and Disease [[electronic resource] /] / edited by Vibha Rani, Umesh Chand Singh Yadav |
Edizione | [1st ed. 2015.] |
Pubbl/distr/stampa | New Delhi : , : Springer India : , : Imprint : Springer, , 2015 |
Descrizione fisica | 1 online resource (427 p.) |
Disciplina |
570
571.936 571.9453 572 |
Soggetto topico |
Oxidative stress
Biochemistry Cytokines Growth factors Apoptosis Enzymology Oxidative Stress Biochemistry, general Cytokines and Growth Factors |
ISBN | 81-322-2035-8 |
Formato | Materiale a stampa |
Livello bibliografico | Monografia |
Lingua di pubblicazione | eng |
Nota di contenuto | Part I – Free Radical Generation -- 1. Production of Reactive Oxygen Species and its Implication in Human Diseases -- 2. Reactive Oxygen Species and Cellular Defense System -- 3. The Noxious Nanoparticles -- 4. Tools and Techniques to measure Oxidative Stress -- Part II – Mechanism of Oxidative Stress -- 5. Impact of Oxidative Stress on Human Health -- 6. Gene-environment interaction in Oxidative Stress-induced Pathologies -- 7. Oxidative Stress Induced Molecular and Genetic Mechanisms in Human Health and Diseases -- 8. Hydrogen Peroxide Sensing and Signalling -- Part III – Oxidative Stress and Diseases -- 9. Oxidative Stress-Induced lipid Peroxidation: Role in Inflammation -- 10. Oxidative Stress and its Biomarkers in Cardiovascular Diseases: An overview -- 11. Free Radicals and Oxidative Stress in Neurodegenerative Disorders -- 12. Thyroid Gland in Free Radical Induced Oxidative Stress -- 13. Oxidative Stress Events and Neuronal Dysfunction in Alzheimer’s Disease: Focus on APE1/Ref-1 Mediated Survival Strategies -- 14. ROS in Carcinogenesis and Anticancerous Drug Induced Toxicity -- 15. Oxidative Stress in Low Birth Weight Newborns -- 16. Oxidative Stress and Diabetes -- 17. Oxidative Stress and Inflammation in Cardiovascular Diseases: Two Sides of the Same Coin.-18. Redox Biology of Aging: Focus on Novel Biomarkers -- Part IV – Strategies to Ameliorate Oxidative Stress Induced Diseases -- 19. Antioxidant Supplements: Friends or Foe? -- 20. Linking Toll-like Receptors Signalling to Oxidative Damage: Potential Role in Cancer Therapy -- 21. Management of Inflammation using Cellular Redox Modifiers -- 22. Oxidative Stress, Antioxidant Status and Redox Signalling in Carcinogenesis -- 23. Role of ROS in Bacterial Resistance and Biofilm Formation and possible Therapeutics -- 24. Antioxidants and other Potent Strategies to Reduce Oxidative stress in semen -- 25. Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: way to Preserve its Anti-oxidative Potential -- 26. Food Protein-Derived Antioxidative Peptides. |
Record Nr. | UNINA-9910298286403321 |
New Delhi : , : Springer India : , : Imprint : Springer, , 2015 | ||
Materiale a stampa | ||
Lo trovi qui: Univ. Federico II | ||
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