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The Blood Brain Barrier and Inflammation / / edited by Ruth Lyck, Gaby Enzmann
The Blood Brain Barrier and Inflammation / / edited by Ruth Lyck, Gaby Enzmann
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (VI, 286 p. 32 illus., 24 illus. in color.)
Disciplina 616.079
Collana Progress in Inflammation Research
Soggetto topico Immunology
Neurosciences
Cell membranes 
Infectious diseases
Cytokines
Growth factors
Membrane Biology
Infectious Diseases
Cytokines and Growth Factors
ISBN 3-319-45514-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto General Introduction to Barrier Mechanisms in the Central Nervous System -- Topological Aspects of the Blood-brain and Blood cerebrospinal Fluid Barriers and their Relevance in Inflammation Research -- The Contribution of the Extracellular Matrix to the BBB in Steady State and Inflammatory Conditions -- Pathophysiology of the Bloodbrain Barrier in Neuroinflammatory Diseases -- Leakage at Blood-neural Barriers -- Blood-Brain Barrier Transporters and Neuroinflammation: Partners in Neuroprotection and in Pathology -- MicroRNAs in Brain Endothelium and Inflammation -- Blood-Brain Barrier Dysfunction during Central Nervous System Autoimmune Diseases -- Pathways Across the Blood Brain Barrier -- Neuroinflammation in Bacterial Meningitis -- Blood Vessels in the Brain: a Signaling Hub in Brain Tumor Inflammation.
Record Nr. UNINA-9910254467803321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
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Bone Morphogenetic Proteins: Systems Biology Regulators / / edited by Slobodan Vukicevic, Kuber T. Sampath
Bone Morphogenetic Proteins: Systems Biology Regulators / / edited by Slobodan Vukicevic, Kuber T. Sampath
Edizione [1st ed. 2017.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
Descrizione fisica 1 online resource (XII, 445 p. 43 illus., 32 illus. in color.)
Disciplina 616.079
Collana Progress in Inflammation Research
Soggetto topico Immunology
Cell biology
Cytokines
Growth factors
Proteins 
Systems biology
Cell Biology
Cytokines and Growth Factors
Protein Science
Systems Biology
ISBN 3-319-47507-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- BMPs: Historic and Future Perspectives -- BMP – Biology -- BMPs in Development -- BMP signaling -- BMP Antagonists - Biology -- BMP and BMP Antagonists - Structure and Function -- BMPs in Orthopaedic Medicine: Promises and Challenges -- BMP6 and Bone Repair -- BMPs in Dental Medicine: Promises and Challenges -- BMPs in Spine -- BMPs in Articular Joints -- BMP Signaling & FOP -- BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases -- BMPs in Inflammation -- BMPs and Angiogenesis -- BMP Signaling in Iron Homeostasis -- BMP Signaling in Pulmonary Arterial Hypertension -- BMP Signaling and Cancer -- BMP Biology in Rare Diseases.
Record Nr. UNINA-9910254481703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2017
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Clinical Medicine Research / / edited by Mieczyslaw Pokorski
Clinical Medicine Research / / edited by Mieczyslaw Pokorski
Edizione [1st ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (vi, 138 pages) : illustrations
Disciplina 616.0072
Collana Clinical and Experimental Biomedicine
Soggetto topico Neurochemistry
Cancer research
Physiotherapy
Cytokines
Growth factors
Cancer Research
Cytokines and Growth Factors
ISBN 3-030-04837-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bioprogressive Paradigm in Physiotherapeutic and Antiaging Strategies: a Review -- Influence of Proprioceptive Neuromuscular Facilitation on Lung Function in Patients after Coronary Artery Bypass Graft Surgery -- Remote Ischemic Preconditioning in Renal Protection During Elective Percutaneous Coronary Intervention -- Prognostic Impact of Extracapsular Lymph Node Invasion on Survival in Non-Small-cell Lung Cancer: a Systematic Review and Meta-Analysis -- Influence of Transurethral Resection of Bladder Cancer on Sexual Function, Anxiety, and Depression -- Cognitive Predictors of Cortical Thickness in Healthy Aging -- Osteoprotegerin, a Receptor Activator of Nuclear Factor kappa B Ligand, and Growth Hormone/Insulin-like Growth Factor-1 Axis in Children with Growth Hormone Deficiency -- Inhibition of Cross-Reactive Carbohydrate Determinants in Allergy Diagnostics -- Effects of Reduced Glutathione on Hydrolytic Enzyme Activity in the Mouse Hepatocytes -- Adaptation to Occupational Exposure to Moderate Endotoxin Concentrations: a Study in Sewage Treatment Plants in Germany -- Effects of Low Level-Laser Therapy in Autism Spectrum Disorder -- Epidemiology of Granulomatosis with Polyangiitis in Poland, 2011–2015. .
Record Nr. UNINA-9910298394903321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
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Cytokine Frontiers : Regulation of Immune Responses in Health and Disease / / edited by Takayuki Yoshimoto, Tomohiro Yoshimoto
Cytokine Frontiers : Regulation of Immune Responses in Health and Disease / / edited by Takayuki Yoshimoto, Tomohiro Yoshimoto
Edizione [1st ed. 2014.]
Pubbl/distr/stampa Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014
Descrizione fisica 1 online resource (398 p.)
Disciplina 616.079
Soggetto topico Immunology
Cytokines
Growth factors
Cell biology
Cytokines and Growth Factors
Cell Biology
ISBN 4-431-54442-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I Cytokines in Inflammatory Disorders -- 1 The Interleukin-1 Family2 IL-6 and Inflammatory Diseases -- 3 The Roles of IL-17A and IL-17F in Infection and Inflammatory Disorders -- 4 IL-18 -- 5 Interleukin-21: A Pleiotropic Mediator of Immunity and Inflammation with Broad Therapeutic Potential -- 6 Interleukin-22: A Bridge Between Epithelial Innate Host Defense and Immune Cells -- 7 IL-23 in Health and Disease -- 8 IL-36: An Epithelial Cytokine Important in Psoriasis -- 9 Anti-TNF Therapy: 20 Years from Our First Therapeutic Adventure -- Part II Cytokines in Allergic Disorders -- 10 Interleukin-25: A Key Initiator of Type 2 Immune Responses -- 11 Interleukin-33: A Multifunctional Alarmin that Promotes Both Health and Disease -- 12 Thymic Stromal Lymphopoietin (TSLP) -- Part III Cytokines in Immunological Tolerance and Anti-inflammation -- 13 Interleukin-10: Cytokines in Anti-inflammation and Tolerance -- 14 Interleukin-27: Regulation of Immune Responses and Disease Development by a Pleiotropic Cytokine with Pro- and Anti-inflammatory Properties -- 15 Interleukin-35: A Novel Mediator of Peripheral Tolerance -- Index.  .
Record Nr. UNINA-9910298314103321
Tokyo : , : Springer Japan : , : Imprint : Springer, , 2014
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Cytokine Storm Syndrome / / edited by Randy Q. Cron, Edward M. Behrens
Cytokine Storm Syndrome / / edited by Randy Q. Cron, Edward M. Behrens
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (XXI, 617 p. 31 illus., 25 illus. in color.)
Disciplina 616.079
616.97
Soggetto topico Immunology
Cytogenetics
Infectious diseases
Cytokines
Growth factors
Infectious Diseases
Cytokines and Growth Factors
ISBN 3-030-22094-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I: Background -- 1. Cytokines in Cytokine Storm Syndrome -- 2. History of hemophagocytic lymphohistiocytosis -- 3.The History of Macrophage Activation Syndrome in Autoimmune Diseases -- 4. Clinical Features of Cytokine Storm Syndrome -- 5. Laboratory Features and Pathology of the Cytokine Storm Syndromes -- 6. Criteria for Cytokine Storm Syndromes -- Part II: Genetics of Cytokine Storm Syndromes -- 7.Genetics of Acquired Cytokine Storm Syndromes -- 8. Genetics of Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis -- Part III: Immunology of Cytokine Storm Syndromes -- 9. CD8+ T cell biology in cytokine storm syndromes -- 10. Immunology of Cytokine Storm Syndromes: Natural Killer Cells -- 11. Myeloid cells in the immunopathogenesis of cytokine storm syndromes -- 12. Cytokines in Cytokine Storm Syndrome -- 13. Primary Immunodeficiencies and Cytokine Storm Syndromes -- Part IV: Infectious Triggers of Cytokine Storm Syndromes -- 14. Infectious Triggers of Cytokine Storm Syndromes: Herpes Virus Family (non-EBV) -- 15. Cytokine Storm Syndromes Associated with Epstein Barr Virus -- 16. Cytokine Storm Syndrome Associated with Hemorrhagic Fever and Other Viruses -- 17. Cytokine Storm Syndrome as a manifestation of Primary HIV Infection -- 18. Bacteria-Associated Cytokine Storm Syndrome -- 19. Zoonotic Bacterial Infections Triggering Cytokine Storm Syndrome -- 20. Parasitic and Fungal Triggers -- Part V: Rheumatic Triggers of Cytokine Storm Syndromes -- 21. Cytokine Storm Syndrome associated with Systemic Juvenile Idiopathic Arthritis -- 22. Systemic Lupus Erythematosus and Cytokine Storm -- 23. Kawasaki Disease -- 24. The Intersections of Autoinflammation and Cytokine Storm -- 25. Macrophage Activation Syndrome in the Setting of Rheumatic Diseases -- Part VI: Other Triggers of Cytokine Storm Syndromes -- 26. Hemophagocytic lymphohistiocytosis in the context of hematological malignancies and solid tumors -- 27. Cytokine Storm and Sepsis induced Multiple Organ Dysfunction Syndrome -- Part VII: Murine Models of Cytokine Storm Syndrome -- 28. Murine Models of Familial Cytokine Storm Syndromes -- 29. Murine Models of Secondary Cytokine Storm Syndromes -- Part VIII: Therapy of Cytokine Storm Syndromes -- 30. Etoposide Therapy of Cytokine Storm Syndromes -- 31. IL-1 Family Blockade -- 32. IL-6 Blockade -- 33. Alternative Therapies for Cytokine Storm Syndromes -- 34. Salvage Therapy and Allogeneic Hematopoietic Cell Transplantation for the Severe Cytokine Storm Syndrome of Hemophagocytic Lymphohistiocytosis.
Record Nr. UNINA-9910349444603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
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Encyclopedia of Signaling Molecules / / edited by Sangdun Choi
Encyclopedia of Signaling Molecules / / edited by Sangdun Choi
Edizione [2nd ed. 2018.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
Descrizione fisica 1 online resource (1893 illus., 1746 illus. in color. eReference.)
Disciplina 572.69603
Soggetto topico Medical genetics
Molecular biology
Cytokines
Growth factors
Cell biology
Proteins 
Bioinformatics
Gene Function
Molecular Medicine
Cytokines and Growth Factors
Cell Biology
Protein-Ligand Interactions
ISBN 3-319-67199-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto From the contents 14-3-3 -- 3-Phosphoinositide-Dependent Kinase 1 (PDK1) -- 5-HTT -- 5-Hydroxytryptamine Receptor 2C -- 5-Hydroxytryptamine Receptor 6 -- A-Kinase Anchoring Protein (AKAP) -- A-RAF -- ABCA Transporters -- ABCA3 -- ACAP1 -- Acetylcholine (Nicotinic) Receptor --  Acetylcholinesterase -- ACK1 -- ACSL4 -- ACT -- Actinin Family -- ADAMTS13 -- ADAP -- ADAP1 --  ADAP2 -- ADCY9 (Adenylyl Cyclase 9) -- Adenomatous Polyposis Coli -- Adenylyl Cyclase --  ADGRB3 -- ADGRG2 -- Adiponectin -- ADP-Ribosylation Factor-6 (ARF6) -- AGAP1 -- AIFM1 --  AIRE -- AKT -- Alpha-1-Syntrophin -- Alpha-2A Adrenergic Receptor -- ALS2 -- AMP-Activated Protein Kinase (AMPK) -- Androgen Receptor (AR) -- ANT -- AP-4 -- APO2L/TRAIL -- Apoptosis Regulator BAX -- Apoptosis-inducing factor 1, mitochondrial -- App -- Aquaporin -- ARAP3 -- ARF1 --  Arl8b -- Aryl Hydrocarbon Receptor -- Ataxia Telangiectasia and Rad3-Related (ATR) -- ATF2 --  ATP-Binding Cassette Subfamily A Member 2 -- Aurora Kinases -- Axin -- AXL -- B Lymphocyte Antigen CD19.
Record Nr. UNINA-9910298435803321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2018
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Encyclopedia of Signaling Molecules [[electronic resource] /] / edited by Sangdun Choi
Encyclopedia of Signaling Molecules [[electronic resource] /] / edited by Sangdun Choi
Edizione [1st ed. 2012.]
Pubbl/distr/stampa New York, NY : , : Springer New York : , : Imprint : Springer, , 2012
Descrizione fisica 1 online resource (300 illus., 100 illus. in color. eReference.)
Disciplina 611.01816
Collana Springer reference
Soggetto topico Medical genetics
Medicine
Cytokines
Cytology
RNA-ligand interactions
Bioinformatics
Gene Function
Molecular Medicine
Cytokines and Growth Factors
Cell Biology
Protein-Ligand Interactions
ISBN 1-4419-0461-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 5-Hydrocytryptamine receptor 3a -- 5-Hydroxytryptamine receptor 2B -- 5-Hydroxytryptamine receptor 2C -- A-Raf -- ABCA -- Ack1 -- ADAP -- Adap1 -- Adenylyl cyclase -- Adenylyl cyclase type 9 -- Adhesion-GPCRs -- ADP-ribosylation factor domain protein 1 -- Ags (Activators of G-protein signaling) -- Aif -- AKAP -- Androgen receptor -- Angiotensin II receptor 2 -- Ant -- AP-3 -- AP-4 -- Apo2L (TRAIL) -- Arap3 -- Arf-like protein 8b -- Arfgap1 -- Arfrp1 -- ATF3 -- Aurora kinase -- Bcl2 family -- Beta-Catenin -- Bradykinin receptor -- Btg/Tob -- c-Myb -- Cadherin -- Calcium channel, voltage-dependent -- Calpain -- Carma1 -- Casein kinase II -- Caspase -- Cbln1 -- CCL3 [chemokine (C-C motif) ligand 3] -- CCL4 [chemokine (C-C motif) ligand 4] -- CCL5 [chemokine (C-C motif) ligand 5] -- CCN -- CCTa -- CD160 -- CD3 -- CD3 zeta -- CD38 -- CD40 -- CD43 -- CD45 -- CD47 -- CD53 -- CD72 -- CD81 -- CD91 -- Cdc7 -- CDK11 -- Ceacam -- Chemokine ligand CX3CL1 -- Chemokine receptor CCR1 -- Cholecystokinin type B receptor (CCK type B receptor) -- Cholecystokinin-1 receptor -- CKIP-1 -- CLEC-1 -- CLEC-2 -- CLEC4E -- CLEC5A -- Clk -- Copine -- CREB -- Csk -- Csk homologous kinase -- CXCL10 [Chemokine (C-X-C motif) ligand 10 or IP-10] -- Cyclin A -- Dap kinase -- Darpp -- Dbf4 -- Dect in-1 -- delta glutamate receptor -- DHHC -- DLK (dual leucine zipper-bearing kinase) -- Dock2 -- Drak2 -- Ect2 (epithelial cell transforming 2 oncogene) -- eIF5 -- eIF6 -- Endo180 -- Endothelin A receptor -- Eph receptor -- EphA3 -- Eps8 (epidermal growth factor receptor pathway substrate 8) -- Erk1/Erk2 -- Erk3/Erk4 -- ERK5/MEK5 -- Estrogen receptor -- Fbln -- FGF (fibroblast growth factor) -- Fgr -- Fhit -- Flotillin 1 -- Flotillin 2 -- Fn14 -- Follicle stimulating hormone receptor -- Formyl peptide receptor -- FOXO1 -- FPR2/ALX -- Frabin -- Frs2 -- FZD (frizzled homolog) -- G alpha i-class G protein alpha subunits -- G protein alpha 12 -- G protein alpha q -- G protein alpha transducin -- G protein beta/gamma -- Gab1 -- Gab2 -- GABA A receptor -- Gadd45 -- Galanin receptor -- Gat (GABA transporter) -- GATA-3 (GATA binding protein 3) -- GCAP (guanylyl cyclase activating protein) -- Geft -- Glucose dependent insulinotropic polypeptide receptor -- Glutamate receptors -- Gpr84 -- Grp94 (HSP90B1) -- Gsk (glycogen synthase kinase) -- GST (glutathione S-transferase) -- Guanylate cyclase -- Guanylyl cyclase C -- Guanylyl cyclase receptors -- HB-EGF (heparin-binding EGF-like growth factor) -- Hipk2 -- Hippocalcin -- hnRNP (heterogeneous nuclear ribonucleoprotein) -- Homer -- Hpk1 -- IAP -- Icmt (Isoprenylcysteine carboxyl methyltransferase) -- Id4 (Inhibitor of DNA binding 4) -- IFN gamma -- IGF1R (insulin-like growth factor 1 receptor) -- IL6 -- IL7 -- Inositol 1,4,5-triphosphate-associated cGMP kinase substrate -- Integrin alpha 1 -- Integrin alpha 11 -- Integrin alpha 2 -- Integrin alpha 4 -- Integrin alpha E -- Integrin alpha V -- IP3 receptor -- IRF5 -- IRG (immunity-related GTPase) -- Itpk1 (inositol 1,3,4-triphosphate 5/6 kinase) -- Itsn -- Laforin -- Lat (linker for activation of T cells) -- LCoR -- LIMK -- Lysyl oxidase -- MAIL (IkBz) -- Malt1 (mucosa associated lymphoid tissue lymphoma translocation gene 1) -- MAP kinases (comprising 14 genes: Erk1, Erk2, Erk3, Erk4, Erk5, Erk7, Jnks (3 isoforms), p38 (4 isoforms) and Nlk) -- Mapkap kinase 2/3 (MK2/3) -- Mapkap kinase 5 (MK5)(PRAK) -- Mark (MAP/microtubule affinity-regulating kinase) -- Mek -- Mek3 -- Mk-styx -- MKK6 -- Mlk (mixed lineage kinase) -- MLTK -- MORF/MOZ lysine acetyltranferase -- Mps1 -- Msk1 -- mTOR -- Mtus1 -- Myc -- MyD88 (myeloid differentiation primary response gene 88) -- MYLK (Myosin linght chain kinase) -- Myosin I (Myo1) -- Myosin III -- Myosin X -- N-WASP -- Ncam (neural cell adhesion molecule) -- Nek (never in mitosis gene a-related expressed kinase) -- Net1 (neuroepithelial cell transforming gene 1 protein) -- Neurotensin receptor -- NF-kB family -- NFAT -- Nherf -- NK receptor -- NKG2D -- NKp46 -- NMT (N-myristoyltransferase) -- Notch -- Nrf2 (NF-E2-related factor2) -- nrip1(Nuclear Receptor-Interacting Protein 1) -- NTPDase family -- Nucleotide receptor P2x -- Nucleotide receptor P2y -- Olfactory receptor -- Opioid receptor -- P-Rex -- p130Cas -- P2Y14 receptor -- P38 MAPK -- P53 -- Pak2 -- PCAF lysine acetyltransferase -- Pea15 -- Phlda1 (T-cell death associated gene)(Pleckstrin homology-like domain, family A, member 1) -- Phosphodiesterase 1 -- Phosphodiesterase 10A -- Phosphodiesterase 4, cAMP specific -- Phosphoinositide 3-kinase -- Phosphoinositide 5-phosphate 4-kinase -- Phospholipase A -- Phospholipase D -- Pim-1 -- Pin1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) -- Pink1 -- PKD -- PKR -- Plasma membrane calcium transporting ATPase -- Plekhg5 -- Polycystin -- PP2C -- Prep -- Prion protein -- Protein farnesyltransferase -- Psgr (prostate specific G-protein coupled receptor) -- PTEN -- PTK6 -- PTPe (RPTPe and cyt-PTPe) -- PTPN3/PTPN4 -- R7BP/R9AP -- Rab18 -- Rab23 -- Rab 7 -- Rab 8 -- Rac -- Raf1 -- Ramp -- Ran -- RANKL and RANK -- Rap GEF family -- Ras (H-, K-, N-Ras) -- RASA1 -- Rasgrf (RAS protein-specific guanine nucleotide-releasing factor) -- RasGRP1 -- Rcan1 (regulator of calcineurin) -- Recoverin -- Relaxin family peptide receptor: 1 & 2 -- Relaxin family peptide receptor: 3 & 4 -- Retinoic acid receptor -- RGS family -- Rgs13 -- RhoC -- Rhodopsin kinase -- Ric8 -- Rin (Ras-like protein in neuron) -- RIN family proteins (RIN1, RIN2 and RIN3) -- ROCK kinases -- Rpn8 -- Rpt -- Rrad (Ras-related associated with diabetes) -- Rsk (p90 ribosomal S6 kinase) -- RyR (ryanodine receptor) -- S100 Proteins -- SAMSN1 (SAM domain, SH3 domain and nuclear localization signal) -- SARA -- Sh2d2a (SH2 domain protein 2A) -- SHIP -- SHP-1 -- SKAP-HOM -- Slp (synaptotagmin-like protein) -- SLP-76 (SH2 domain containing leukocyte protein of 76kDa) -- SOCS -- Somatostatin receptor -- Sonic hedgehog -- Sphingosine-1-phosphate -- Src -- Sry -- STAT -- Striatal-Enriched Protein Tyrosine Phosphatase (STEP) -- Sulfiredoxin -- SWI/SNF (SWItch/Sucrose NonFermentable) -- TBCCD1 -- Tead -- The Steroid Receptor Coactivator Family -- Thrombospondin 1 -- TLR adaptor protein -- TLR3 -- TLR4 -- TLR5 -- TLR9 -- TMEM85 (transmembrane protein 85) -- TPD52 (tumor protein D52) -- Tpl2 -- TRAF6 -- TRAIL receptor 1/2 (death receptor 4/5, DR4/5) -- Trb (tribbles) -- Trp (transient receptor potential cation channel) -- Urokinase-type plasminogen activator receptor -- UT (Urea transporter) -- VAMP1/2/3/7 -- Vav Family -- Vitamin D receptor -- VRK1 -- VRK2 -- VRK3 -- WASH -- ZAP-70 -- ZNF202 (zinc finger protein 202; Zfp202) -- ZnT (zinc transporter).
Record Nr. UNINA-9910484235003321
New York, NY : , : Springer New York : , : Imprint : Springer, , 2012
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Endocannabinoids / / edited by Roger G. Pertwee
Endocannabinoids / / edited by Roger G. Pertwee
Edizione [1st ed. 2015.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (477 p.)
Disciplina 615.7827
Collana Handbook of Experimental Pharmacology
Soggetto topico Pharmacology
Cell biology
Neurosciences
Psychopharmacology
Immunology
Cytokines
Growth factors
Pharmacology/Toxicology
Cell Biology
Cytokines and Growth Factors
ISBN 3-319-20825-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Preface; The Endocannabinoid System: A Look Back and Ahead; Contents; Endocannabinoids and Their Pharmacological Actions; 1 Introduction; 2 Evidence That Certain Endogenous Compounds Target Cannabinoid Receptors Orthosterically; 2.1 Evidence from Binding Assays; 2.2 Evidence from Two Functional Bioassays; 2.2.1 [35S]GTPgammaS Binding Assay; 2.2.2 Cyclic AMP Assay; 3 Non-Cannabinoid Receptors and Channels Targeted by Endogenous Cannabinoid Receptor Ligands at Submicromolar Concentrations; 3.1 Non-Cannabinoid G Protein-Coupled Receptors; 3.1.1 GPR55; 3.2 Ligand-Gated Ion Channels
3.2.1 5-HT3 Receptors3.2.2 Nicotinic Acetylcholine Receptors; 3.2.3 Glycine Receptors; 3.2.4 Ionotropic Glutamate NMDA Receptors; 3.3 Transient Receptor Potential Channels; 3.3.1 TRPV1; 3.3.2 TRPM8 Channels; 3.4 Voltage-Gated Calcium Channels; 3.4.1 T-Type Cav3 Calcium Channels; 3.5 Potassium Channels; 3.5.1 ATP-Sensitive Inward Rectifier KATP Channels of the 2TM Domain Family; 3.5.2 Voltage-Gated Kv and KCa Channels of the 6TM Domain Family; 4 Allosteric Endocannabinoids; 5 Conclusions; References; Biosynthesis and Fate of Endocannabinoids
1 Endocannabinoids and Endocannabinoid-Like Compounds2 Biosynthesis of the Endocannabinoids; 3 Uptake of the Endocannabinoids: Proposed Mechanisms; 4 Degradation of the Endocannabinoids; 4.1 FAAH and NAAA; 4.2 MGL, ABHD6 and ABHD12; 5 Conclusions; References; Distribution of the Endocannabinoid System in the Central Nervous System; 1 Introduction; 1.1 Overview; 1.2 Cells Expressing Components of the ECS; 1.3 Subcellular Localization of CB1 Cannabinoid Receptors; 2 Retina; 2.1 Receptors; 2.2 Synthetic Enzymes; 2.3 Degradative Enzymes; 3 Cerebral Cortex; 3.1 Neocortex; 3.1.1 Receptors
3.1.2 Synthetic Enzymes3.1.3 Degradative Enzymes; 3.2 Olfactory Areas (Olfactory Bulb, Piriform Cortex, Associated Regions); 3.2.1 Receptors; 3.2.2 Synthetic Enzymes; 3.2.3 Degradative Enzymes; 3.3 Hippocampal Formation; 3.3.1 Receptors; 3.3.2 Synthetic Enzymes; 3.3.3 Degradative Enzymes; 3.4 Cortical Subplate (Other Amygdala Nuclei); 3.4.1 Receptors; 3.4.2 Synthetic Enzymes; 3.4.3 Degradative Enzymes; 4 Subcortical Nuclei (Striatum, Basal Ganglia); 4.1 Striatum (Dorsal, Caudate); 4.1.1 Receptors; 4.1.2 Synthetic Enzymes; 4.1.3 Degradative Enzymes; 4.2 Striatum (Ventral, Accumbens)
4.2.1 Receptors4.2.2 Synthetic Enzymes; 4.2.3 Degradative Enzymes; 4.3 Striatum Medial (Lateral Septum, Septohippocampal, etc.); 4.3.1 Receptors; 4.3.2 Synthetic Enzymes; 4.3.3 Degradative Enzymes; 4.4 Striatum Caudal (Striatum-like Amygdala Nuclei, Central Amygdala, Bed Nucleus, Medial Amygdala, Etc.); 4.4.1 Receptors; 5 Cerebellum and Associated Nuclei; 5.1 Cerebellar Cortex; 5.1.1 Receptors; 5.1.2 Synthetic Enzymes; 5.1.3 Degradative Enzymes; 5.2 Deep Cerebellar Nuclei (Fastigial, Interpos, Dentate Nucleus); 5.2.1 Receptors; 5.2.2 Synthetic Enzymes; 5.2.3 Degradative Enzymes; 6 Brainstem
6.1 Diencephalon
Record Nr. UNINA-9910298267903321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2015
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Extracellular Matrix in Development / / edited by Douglas W. DeSimone, Robert Mecham
Extracellular Matrix in Development / / edited by Douglas W. DeSimone, Robert Mecham
Edizione [1st ed. 2013.]
Pubbl/distr/stampa Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
Descrizione fisica 1 online resource (259 p.)
Disciplina 599.03
Collana Biology of Extracellular Matrix
Soggetto topico Developmental biology
Cell biology
Regenerative medicine
Tissue engineering
Cytokines
Growth factors
Stem cells
Developmental Biology
Cell Biology
Regenerative Medicine/Tissue Engineering
Cytokines and Growth Factors
Stem Cells
ISBN 3-642-35935-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I Informational signals in extracellular matrix and matrix influences on cell movement in the developing embryo -- Part II Extracellular matrix-direct morphogenesis, growth factor signaling, and maintenance of the stem cell niche -- Part III Model organisms and the lexicon of developmental signals associated with the extracellular matrix.
Record Nr. UNINA-9910739447703321
Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2013
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Free Radicals in Human Health and Disease [[electronic resource] /] / edited by Vibha Rani, Umesh Chand Singh Yadav
Free Radicals in Human Health and Disease [[electronic resource] /] / edited by Vibha Rani, Umesh Chand Singh Yadav
Edizione [1st ed. 2015.]
Pubbl/distr/stampa New Delhi : , : Springer India : , : Imprint : Springer, , 2015
Descrizione fisica 1 online resource (427 p.)
Disciplina 570
571.936
571.9453
572
Soggetto topico Oxidative stress
Biochemistry
Cytokines
Growth factors
Apoptosis
Enzymology
Oxidative Stress
Biochemistry, general
Cytokines and Growth Factors
ISBN 81-322-2035-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I – Free Radical Generation -- 1. Production of Reactive Oxygen Species and its Implication in Human Diseases -- 2. Reactive Oxygen Species and Cellular Defense System -- 3. The Noxious Nanoparticles -- 4. Tools and Techniques to measure Oxidative Stress -- Part II – Mechanism of Oxidative Stress -- 5. Impact of Oxidative Stress on Human Health -- 6. Gene-environment interaction in Oxidative Stress-induced Pathologies -- 7. Oxidative Stress Induced Molecular and Genetic Mechanisms in Human Health and Diseases -- 8. Hydrogen Peroxide Sensing and Signalling -- Part III – Oxidative Stress and Diseases -- 9. Oxidative Stress-Induced lipid Peroxidation: Role in Inflammation -- 10. Oxidative Stress and its Biomarkers in Cardiovascular Diseases: An overview -- 11. Free Radicals and Oxidative Stress in Neurodegenerative Disorders -- 12. Thyroid Gland in Free Radical Induced Oxidative Stress -- 13. Oxidative Stress Events and Neuronal Dysfunction in Alzheimer’s Disease: Focus on APE1/Ref-1 Mediated Survival Strategies -- 14. ROS in Carcinogenesis and Anticancerous Drug Induced Toxicity -- 15. Oxidative Stress in Low Birth Weight Newborns -- 16. Oxidative Stress and Diabetes -- 17. Oxidative Stress and Inflammation in Cardiovascular Diseases: Two Sides of the Same Coin.-18. Redox Biology of Aging: Focus on Novel Biomarkers -- Part IV – Strategies to Ameliorate Oxidative Stress Induced Diseases -- 19. Antioxidant Supplements: Friends or Foe? -- 20. Linking Toll-like Receptors Signalling to Oxidative Damage: Potential Role in Cancer Therapy -- 21. Management of Inflammation using Cellular Redox Modifiers -- 22. Oxidative Stress, Antioxidant Status and Redox Signalling in Carcinogenesis -- 23. Role of ROS in Bacterial Resistance and Biofilm Formation and possible Therapeutics -- 24. Antioxidants and other Potent Strategies to Reduce Oxidative stress in semen -- 25. Nano-encapsulation of a Natural Polyphenol, Green Tea Catechins: way to Preserve its Anti-oxidative Potential -- 26. Food Protein-Derived Antioxidative Peptides.
Record Nr. UNINA-9910298286403321
New Delhi : , : Springer India : , : Imprint : Springer, , 2015
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