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Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs
| Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs |
| Pubbl/distr/stampa | [Place of publication not identified], : AHRQ, 2007 |
| Descrizione fisica | 1 online resource |
| Disciplina | 615/.78 |
| Collana | Evidence report/technology assessment Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs) |
| Soggetto topico |
Serotonin uptake inhibitors - Chemotherapy
Cytochrome P-450 Depression, Mental Pharmacogenetics Genetic Variation Depressive Disorder Serotonin Agents Age Groups Neurotransmitter Uptake Inhibitors Cytochromes Mixed Function Oxygenases Hemeproteins Genetic Phenomena Mood Disorders Persons Neurotransmitter Agents Oxygenases Enzymes and Coenzymes Proteins Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Oxidoreductases Mental Disorders Pharmacologic Actions Amino Acids, Peptides, and Proteins Enzymes Chemical Actions and Uses Polymorphism, Genetic Cytochrome P-450 Enzyme System Adult Depressive Disorder, Major Serotonin Uptake Inhibitors Health & Biological Sciences Pharmacy, Therapeutics, & Pharmacology |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910698235503321 |
| [Place of publication not identified], : AHRQ, 2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The ubiquitous roles of cytochrome P450 proteins [[electronic resource] /] / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
| The ubiquitous roles of cytochrome P450 proteins [[electronic resource] /] / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel |
| Pubbl/distr/stampa | Chichester, : John Wiley, c2007 |
| Descrizione fisica | 1 online resource (680 p.) |
| Disciplina |
572.6
572.7 |
| Altri autori (Persone) |
SigelAstrid
SigelHelmut SigelRoland K. O |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Cytochrome P-450
Cytochromes |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-85473-1
9786610854738 0-470-02815-7 0-470-02814-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metal Ions in Life Sciences; Historical Development and Perspectives of the Series; Preface to Volume 3; Contents; Contributors to Volume 3; Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series; Contents of Volumes in the Metal Ions in Life Sciences Series; 1 Diversities and Similarities in P450 Systems: An Introduction; 1. Oxygenases: Mediators of Biochemical Diversity; 2. P450 Superfamily: Diversity at the Sequence Level; 3. Diversity of P450 Structures: Folds and Conformations for Functions; 4. Diversity in P450 Mechanisms; 5. Diversity in Regulation Across the Superfamily
6. Diversity in the Evolution of Common Metabolic Functions7. Summary and Outlook; Acknowledgments; Abbreviations; References; 2 Structural and Functional Mimics of Cytochromes P450; 1. Introduction; 2. Iron Porphyrins Carrying a Thiolate or Modified Thiolate Ligand; 3. Structurally Remote P450 Mimics; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 3 Structures of P450 Proteins and Their Molecular Phylogeny; 1. Introduction; 2. P450 Evolution; 3. P450 Families and Subfamilies; 4. P450 Structures; 5. Variation in P450 Function and Fold; 6. Archaeon P450s 7. Summary and ConclusionsAcknowledgments; Abbreviations; References; 4 Aquatic P450 Species; 1. Introduction. 'P450s Under the Surface'; 2. Diversity of Aquatic Species; 3. P450 Activities in Aquatic Invertebrates; 4. Aquatic P450 Gene Families Identified; 5. How Can We Use Information About P450s in Aquatic Species?; 6. Conclusions and Outlook; Acknowledgments; Abbreviations; References; 5 The Electrochemistry of Cytochrome P450; 1. Introduction; 2. Redox Titration (Potentiometric Equilibrium) Measurements; 3. Voltammetric (Dynamic) Measurements; 4. Conclusions; Acknowledgments AbbreviationsReferences; 6 P450 Electron Transfer Reactions; 1. Introduction; 2. Catalytic Cycles; 3. Electron Tunneling Wires; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 7 Leakage in Cytochrome P450 Reactions in Relation to Protein Structural Properties; 1. Introduction; 2. Protein Structural Parameters; 3. The Reaction Cycle of Cytochrome P450; 4. Protein Structural Parameters and Extent of Competitive Reactions; 5. Concluding Remarks; Acknowledgments; Abbreviations; References; 8 Cytochromes P450 - Structural Basis for Binding and Catalysis; 1. Introduction 2. Ligand Binding: Substrate Recognition and Access to the Distal Pocket3. Architecture of the Active Site of CYP101; 4. The Distal Acid-Alcohol Pair; 5. Experimental Characterization of Reaction Intermediates. Radiolysis as a Tool to Study Redox Reactions; 6. Crystal Structures of Oxy-Ferrous Complexes; 7. Mechanism: Summary, Conclusions, Speculations; Acknowledgments; Abbreviations; References; 9 Beyond Heme-Thiolate Interactions: Roles of the Secondary Coordination Sphere in Cytochrome P450 Systems; 1. Overview of Cytochrome P450 Active Site Structure 2. Secondary Coordination Sphere on the Proximal Side |
| Record Nr. | UNINA-9910143726503321 |
| Chichester, : John Wiley, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The ubiquitous roles of cytochrome P450 proteins [[electronic resource] /] / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
| The ubiquitous roles of cytochrome P450 proteins [[electronic resource] /] / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel |
| Pubbl/distr/stampa | Chichester, : John Wiley, c2007 |
| Descrizione fisica | 1 online resource (680 p.) |
| Disciplina |
572.6
572.7 |
| Altri autori (Persone) |
SigelAstrid
SigelHelmut SigelRoland K. O |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Cytochrome P-450
Cytochromes |
| ISBN |
1-280-85473-1
9786610854738 0-470-02815-7 0-470-02814-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metal Ions in Life Sciences; Historical Development and Perspectives of the Series; Preface to Volume 3; Contents; Contributors to Volume 3; Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series; Contents of Volumes in the Metal Ions in Life Sciences Series; 1 Diversities and Similarities in P450 Systems: An Introduction; 1. Oxygenases: Mediators of Biochemical Diversity; 2. P450 Superfamily: Diversity at the Sequence Level; 3. Diversity of P450 Structures: Folds and Conformations for Functions; 4. Diversity in P450 Mechanisms; 5. Diversity in Regulation Across the Superfamily
6. Diversity in the Evolution of Common Metabolic Functions7. Summary and Outlook; Acknowledgments; Abbreviations; References; 2 Structural and Functional Mimics of Cytochromes P450; 1. Introduction; 2. Iron Porphyrins Carrying a Thiolate or Modified Thiolate Ligand; 3. Structurally Remote P450 Mimics; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 3 Structures of P450 Proteins and Their Molecular Phylogeny; 1. Introduction; 2. P450 Evolution; 3. P450 Families and Subfamilies; 4. P450 Structures; 5. Variation in P450 Function and Fold; 6. Archaeon P450s 7. Summary and ConclusionsAcknowledgments; Abbreviations; References; 4 Aquatic P450 Species; 1. Introduction. 'P450s Under the Surface'; 2. Diversity of Aquatic Species; 3. P450 Activities in Aquatic Invertebrates; 4. Aquatic P450 Gene Families Identified; 5. How Can We Use Information About P450s in Aquatic Species?; 6. Conclusions and Outlook; Acknowledgments; Abbreviations; References; 5 The Electrochemistry of Cytochrome P450; 1. Introduction; 2. Redox Titration (Potentiometric Equilibrium) Measurements; 3. Voltammetric (Dynamic) Measurements; 4. Conclusions; Acknowledgments AbbreviationsReferences; 6 P450 Electron Transfer Reactions; 1. Introduction; 2. Catalytic Cycles; 3. Electron Tunneling Wires; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 7 Leakage in Cytochrome P450 Reactions in Relation to Protein Structural Properties; 1. Introduction; 2. Protein Structural Parameters; 3. The Reaction Cycle of Cytochrome P450; 4. Protein Structural Parameters and Extent of Competitive Reactions; 5. Concluding Remarks; Acknowledgments; Abbreviations; References; 8 Cytochromes P450 - Structural Basis for Binding and Catalysis; 1. Introduction 2. Ligand Binding: Substrate Recognition and Access to the Distal Pocket3. Architecture of the Active Site of CYP101; 4. The Distal Acid-Alcohol Pair; 5. Experimental Characterization of Reaction Intermediates. Radiolysis as a Tool to Study Redox Reactions; 6. Crystal Structures of Oxy-Ferrous Complexes; 7. Mechanism: Summary, Conclusions, Speculations; Acknowledgments; Abbreviations; References; 9 Beyond Heme-Thiolate Interactions: Roles of the Secondary Coordination Sphere in Cytochrome P450 Systems; 1. Overview of Cytochrome P450 Active Site Structure 2. Secondary Coordination Sphere on the Proximal Side |
| Record Nr. | UNINA-9910830041303321 |
| Chichester, : John Wiley, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
The ubiquitous roles of cytochrome P450 proteins / / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
| The ubiquitous roles of cytochrome P450 proteins / / edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel |
| Pubbl/distr/stampa | Chichester, : John Wiley, c2007 |
| Descrizione fisica | 1 online resource (680 p.) |
| Disciplina |
572.6
572.7 |
| Altri autori (Persone) |
SigelAstrid
SigelHelmut SigelRoland K. O |
| Collana | Metal ions in life sciences |
| Soggetto topico |
Cytochrome P-450
Cytochromes |
| ISBN |
1-280-85473-1
9786610854738 0-470-02815-7 0-470-02814-9 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Metal Ions in Life Sciences; Historical Development and Perspectives of the Series; Preface to Volume 3; Contents; Contributors to Volume 3; Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series; Contents of Volumes in the Metal Ions in Life Sciences Series; 1 Diversities and Similarities in P450 Systems: An Introduction; 1. Oxygenases: Mediators of Biochemical Diversity; 2. P450 Superfamily: Diversity at the Sequence Level; 3. Diversity of P450 Structures: Folds and Conformations for Functions; 4. Diversity in P450 Mechanisms; 5. Diversity in Regulation Across the Superfamily
6. Diversity in the Evolution of Common Metabolic Functions7. Summary and Outlook; Acknowledgments; Abbreviations; References; 2 Structural and Functional Mimics of Cytochromes P450; 1. Introduction; 2. Iron Porphyrins Carrying a Thiolate or Modified Thiolate Ligand; 3. Structurally Remote P450 Mimics; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 3 Structures of P450 Proteins and Their Molecular Phylogeny; 1. Introduction; 2. P450 Evolution; 3. P450 Families and Subfamilies; 4. P450 Structures; 5. Variation in P450 Function and Fold; 6. Archaeon P450s 7. Summary and ConclusionsAcknowledgments; Abbreviations; References; 4 Aquatic P450 Species; 1. Introduction. 'P450s Under the Surface'; 2. Diversity of Aquatic Species; 3. P450 Activities in Aquatic Invertebrates; 4. Aquatic P450 Gene Families Identified; 5. How Can We Use Information About P450s in Aquatic Species?; 6. Conclusions and Outlook; Acknowledgments; Abbreviations; References; 5 The Electrochemistry of Cytochrome P450; 1. Introduction; 2. Redox Titration (Potentiometric Equilibrium) Measurements; 3. Voltammetric (Dynamic) Measurements; 4. Conclusions; Acknowledgments AbbreviationsReferences; 6 P450 Electron Transfer Reactions; 1. Introduction; 2. Catalytic Cycles; 3. Electron Tunneling Wires; 4. Concluding Remarks; Acknowledgments; Abbreviations; References; 7 Leakage in Cytochrome P450 Reactions in Relation to Protein Structural Properties; 1. Introduction; 2. Protein Structural Parameters; 3. The Reaction Cycle of Cytochrome P450; 4. Protein Structural Parameters and Extent of Competitive Reactions; 5. Concluding Remarks; Acknowledgments; Abbreviations; References; 8 Cytochromes P450 - Structural Basis for Binding and Catalysis; 1. Introduction 2. Ligand Binding: Substrate Recognition and Access to the Distal Pocket3. Architecture of the Active Site of CYP101; 4. The Distal Acid-Alcohol Pair; 5. Experimental Characterization of Reaction Intermediates. Radiolysis as a Tool to Study Redox Reactions; 6. Crystal Structures of Oxy-Ferrous Complexes; 7. Mechanism: Summary, Conclusions, Speculations; Acknowledgments; Abbreviations; References; 9 Beyond Heme-Thiolate Interactions: Roles of the Secondary Coordination Sphere in Cytochrome P450 Systems; 1. Overview of Cytochrome P450 Active Site Structure 2. Secondary Coordination Sphere on the Proximal Side |
| Record Nr. | UNINA-9910876637503321 |
| Chichester, : John Wiley, c2007 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
- Cytochrome P-450 (4)
-
Cytochromes
(4)
- Adult (1)
- Age Groups (1)
- Amino Acids, Peptides, and Proteins (1)