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Lynch Syndrome : Molecular Mechanism and Current Clinical Practice / / edited by Naohiro Tomita
| Lynch Syndrome : Molecular Mechanism and Current Clinical Practice / / edited by Naohiro Tomita |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Springer Singapore, 2020 |
| Descrizione fisica | 1 online resource (148 pages) |
| Disciplina | 616.994042 |
| Soggetto topico |
Oncology
Rectum—Surgery Gastroenterology Colorectal Neoplasms, Hereditary Nonpolyposis Chemoprevention Colorectal Surgery Càncer colorectal Malalties hereditàries Oncologia |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 981-15-6891-X |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1 Molecular mechanism of Lynch syndrome -- 2 Clinical features of Lynch syndrome -- 3 Pathology of Lynch syndrome-associated tumors -- 4 Immunohistochemistry for mismatch repair proteins -- 5 Genetic analysis for Lynch syndrome -- 6 Lynch syndrome-associated gynecological malignancies -- 7 Lynch syndrome-associated urological malignancies -- 8 Screening for Lynch syndrome -- 9 Surveillance Colonoscopy for Lynch Syndrome Patients -- 10 Surgical approach for colorectal cancer in patients with Lynch syndrome -- 11 Immunotherapy for Lynch syndrome patients -- 12 Chemoprevention for Lynch syndrome-associated malignancies -- 13 International collaboration for Lynch syndrome. |
| Record Nr. | UNINA-9910863109403321 |
| Springer Singapore, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Mismatch repair deficient cancers diagnosis, treatment and prevention / / John Burn
| Mismatch repair deficient cancers diagnosis, treatment and prevention / / John Burn |
| Autore | Burn John, MD, MRCP |
| Pubbl/distr/stampa | London, : Henry Stewart Talks, 2014 |
| Descrizione fisica | 1 online resource (1 streaming video file (44 min.) : color, sound) |
| Collana | Molecular genetics of human disease |
| Soggetto topico |
Aspirin
Cancer - Genetic aspects Colon (Anatomy) - Cancer - Genetic aspects Colon (Anatomy) - Cancer - Treatment Medical genetics Molecular genetics Rectum - Cancer - Genetic aspects Rectum - Cancer - Treatment Aspirin - therapeutic use Biomarkers Colorectal Neoplasms - diagnosis Colorectal Neoplasms - genetics Colorectal Neoplasms - therapy Colorectal Neoplasms, Hereditary Nonpolyposis DNA Mismatch Repair Genetics, Medical Microsatellite Instability Microsatellite Repeats |
| Formato | Videoregistrazioni  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Contents: Lynch syndrome (underlying single gene defect) -- Microsatellites -- Important genes containing repeat sequences -- MSI testing (5 marker panel) -- Mismatch repair (MMR) -- The genomic pathogenesis of colorectal cancer (CRC) -- EGFR and BRAF mutant inhibition -- BRAF colon cancer project -- Methotrexate & MMR deficient tumours -- Africans & bowel cancer (Dennis Burkitt) -- Cancer prevention program (CaPP) -- NSAIDs and reduced colorectal cancer risk -- Aspirin effect on polyps in FAP and colorectal adenoma -- The prevention paradox -- CaPP2 (Colorectal & Lynch syndrome cancers) -- Meta-analysis of cancer deaths with aspirin treatment -- CRCs in people on aspirin (mostly COX2 negative) -- Individual response to aspirin in cancer prevention -- History of salicylate as an essential nutrient -- CaPP3 study -- Peptides created by slippage in microsatellite coding -- Antibodies as a possible biomarker for Lynch syndrome -- The Micoryx vaccine. |
| Record Nr. | UNINA-9910596997903321 |
Burn John, MD, MRCP
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| London, : Henry Stewart Talks, 2014 | ||
| Videoregistrazioni | ||
| Lo trovi qui: Univ. Federico II | ||
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