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Clostridioides Difficile : infections, risk factors, prevention and treatment / / Henning Sommermeyer, Jacek Pia̜tek
Clostridioides Difficile : infections, risk factors, prevention and treatment / / Henning Sommermeyer, Jacek Pia̜tek
Autore Sommermeyer Henning
Pubbl/distr/stampa Cham, Switzerland : , : Springer, , [2021]
Descrizione fisica 1 online resource (96 pages)
Disciplina 616.3447
Soggetto topico Clostridium difficile
Clostridi
Soggetto genere / forma Llibres electrònics
ISBN 3-030-81100-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- About the Authors -- Abbreviations -- List of Figures -- List of Tables -- 1: Introduction -- 2: Microbiology -- 2.1 Taxonomy -- 2.2 Genome -- 2.3 Epigenome -- 2.4 Life Cycle of C. difficile During Infection -- 2.4.1 Spore -- 2.4.1.1 Spore Core -- 2.4.1.2 Inner Membrane -- 2.4.1.3 Germ Cell Wall -- 2.4.1.4 Cortex -- 2.4.1.5 Outer Membrane -- 2.4.1.6 Coat and Exosporium -- 2.4.2 Germination -- 2.4.2.1 Germinosome Model -- 2.4.2.2 Lock-and-Key Model -- 2.4.3 Sporulation -- References -- 3: Pathophysiology of C. difficile -- 3.1 Toxins TcdA and TcdB -- 3.2 Genetics of TcdA and TcdB -- 3.3 Pathogenicity Locus -- 3.4 Toxinotypes of C. difficile Isolates -- 3.5 Environmental Signals Regulating Toxin Expression -- 3.6 Mechanism of Action and Functional Domains of TcdA and TcdB -- 3.7 Cell Surface Receptors for TcdA and TcdB -- 3.8 Receptor-Mediated Endocytosis and Membrane Translocation -- 3.9 Modification of Small GTPase Proteins as Host Cell Targets of TcdA and TcdB -- 3.10 Influence of TcdA and TcdB on Cell Physiology -- 3.11 Impact on Cell Morphology -- 3.12 Impact on Small GTPase Signaling Pathways -- 3.13 Role of TcdA and TcdB in Disease -- 3.14 Other Toxins Produced by C. difficile -- 3.15 Toxin Profiles of Clinical Isolates -- References -- 4: Epidemiology -- 4.1 Historical Perspective -- 4.2 Hospital- and Community-Acquired CDI -- 4.3 Hypervirulent C. difficile Strain Ribotype 027 (NAP1/BI) -- 4.4 Other Strains of C. difficile -- 4.5 Dual Strain Infections -- 4.6 CDI in Children -- 4.7 Recurrent CDI -- References -- 5: Risk Factors for CDI -- 5.1 Exposure to Healthcare Institutions -- 5.2 Antibiotics -- 5.3 Proton Pump Inhibitors -- 5.4 Advanced Age as Risk Factor for CDI -- 5.5 Cancer Therapy as Risk Factor for CDI.
5.6 Other Risk Factors for CDI -- 5.7 Risk Factors for Community-Acquired CDI -- 5.8 Risk Factors for Recurrent CDI -- 5.9 CDI Risk Factors in Children -- References -- 6: Diagnosis of CDI -- References -- 7: Clinical Picture of CDI -- 7.1 From Asymptomatic Carriers to Life-Threatening Presentations -- 7.2 Pseudomembranous Colitis -- References -- 8: Treatment of CDI -- 8.1 Antibiotics-Based Therapy -- 8.1.1 Antibiotics Used for Treatment of CDI -- 8.1.2 AB-Treatment of an Initial, Non-severe CDI Episode in Adults -- 8.1.3 AB-Treatment of a Fulminant Episode of CDI in Adults -- 8.1.4 AB-Treatment of a First or Multiple Recurrence of CDI in Adults -- 8.1.5 AB-Treatment of Non-severe Initial or First Recurrent CDI in Children -- 8.1.6 AB-Treatment of an Initial Episode of Severe CDI in Children -- 8.1.7 AB-Treatment of Second or Greater Episode of Recurrent CDI in Children -- 8.2 Fecal Microbiota Transplantation as Treatment for CDI -- 8.3 Probiotics and Synbiotics as Treatment for CDI -- 8.4 Surgical Treatment of Complicated CDI -- References -- 9: Prophylaxis of CDI -- 9.1 Probiotics and Synbiotics for Prophylaxis of CDI -- 9.2 Bezlotoxumab for the Prevention of Recurrent CDI -- References -- 10: Summary and Discussion -- 10.1 Spores -- 10.2 Pathophysiology -- 10.3 Epidemiology -- 10.4 Risk Factors -- 10.5 Diagnosis -- 10.6 Clinical Picture -- 10.7 Treatment -- 10.8 Prophylaxis -- 10.9 General Outlook.
Record Nr. UNINA-9910502658703321
Sommermeyer Henning  
Cham, Switzerland : , : Springer, , [2021]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridium difficile [[electronic resource] ] : New Challenges for an Old Foe
Clostridium difficile [[electronic resource] ] : New Challenges for an Old Foe
Autore Tillotson Glenn S
Edizione [1st ed.]
Pubbl/distr/stampa London, : Future Medicine Ltd, 2013
Descrizione fisica 1 online resource (157 p.)
Disciplina 616.92
Altri autori (Persone) WeissKarl
Soggetto topico Clostridium difficile
Clostridium diseases -- Diagnosis
Clostridium diseases
Clostridium
Diarrhea
Soggetto genere / forma Electronic books.
ISBN 1-78084-315-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; Foreword. Clostridium difficile: new challenges for an old foe; 1. Clostridium difficile infection: a global threat; 2. Pathogenicity mechanisms of Clostridium difficile; 3. Immunology and Clostridium difficile; 4. The microbiome and Clostridium difficile infection; 5. Economic burden of Clostridium difficile infection; 6. Laboratory diagnosis of Clostridium difficile infection; 7. Conventional therapeutics for Clostridium difficile infection; 8. Infection control issues in Clostridium difficile
9. Future and alternative approaches to managing Clostridium difficile infectionEpilogue. Recent advances with Clostridium difficile; Index
Record Nr. UNINA-9910465457703321
Tillotson Glenn S  
London, : Future Medicine Ltd, 2013
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridium Difficile : A Comprehensive Overview / / edited by Shymaa Enany
Clostridium Difficile : A Comprehensive Overview / / edited by Shymaa Enany
Pubbl/distr/stampa Rijeka, Croatia : , : IntechOpen, , 2017
Descrizione fisica 1 online resource (160 pages) : illustrations
Disciplina 616.3447
Soggetto topico Clostridium difficile
ISBN 953-51-4643-2
953-51-3428-0
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Altri titoli varianti Clostridium difficile
Record Nr. UNINA-9910317847003321
Rijeka, Croatia : , : IntechOpen, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridium difficile : new challenges for an old foe / / editors, Glenn S. Tillotson, Karl Weiss
Clostridium difficile : new challenges for an old foe / / editors, Glenn S. Tillotson, Karl Weiss
Edizione [1st ed.]
Pubbl/distr/stampa London, England : , : Future Medicine Ltd., , [2013]
Descrizione fisica 1 online resource (157 p.)
Disciplina 616.3447
Soggetto topico Clostridium difficile
Clostridium diseases
ISBN 1-78084-315-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; Foreword. Clostridium difficile: new challenges for an old foe; 1. Clostridium difficile infection: a global threat; 2. Pathogenicity mechanisms of Clostridium difficile; 3. Immunology and Clostridium difficile; 4. The microbiome and Clostridium difficile infection; 5. Economic burden of Clostridium difficile infection; 6. Laboratory diagnosis of Clostridium difficile infection; 7. Conventional therapeutics for Clostridium difficile infection; 8. Infection control issues in Clostridium difficile
9. Future and alternative approaches to managing Clostridium difficile infectionEpilogue. Recent advances with Clostridium difficile; Index
Record Nr. UNINA-9910792287003321
London, England : , : Future Medicine Ltd., , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridium difficile : new challenges for an old foe / / editors, Glenn S. Tillotson, Karl Weiss
Clostridium difficile : new challenges for an old foe / / editors, Glenn S. Tillotson, Karl Weiss
Edizione [1st ed.]
Pubbl/distr/stampa London, England : , : Future Medicine Ltd., , [2013]
Descrizione fisica 1 online resource (157 p.)
Disciplina 616.3447
Soggetto topico Clostridium difficile
Clostridium diseases
ISBN 1-78084-315-1
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Title page; Copyright page; Contents; Foreword. Clostridium difficile: new challenges for an old foe; 1. Clostridium difficile infection: a global threat; 2. Pathogenicity mechanisms of Clostridium difficile; 3. Immunology and Clostridium difficile; 4. The microbiome and Clostridium difficile infection; 5. Economic burden of Clostridium difficile infection; 6. Laboratory diagnosis of Clostridium difficile infection; 7. Conventional therapeutics for Clostridium difficile infection; 8. Infection control issues in Clostridium difficile
9. Future and alternative approaches to managing Clostridium difficile infectionEpilogue. Recent advances with Clostridium difficile; Index
Record Nr. UNINA-9910808327103321
London, England : , : Future Medicine Ltd., , [2013]
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Autore Kato Hideaki
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, 2010
Descrizione fisica 1 online resource (62 p.)
Disciplina 616.9/31
Altri autori (Persone) KatoHaru
Collana Public health in the 21st century
Bacteriology research developments
Soggetto topico Clostridium diseases
Clostridium difficile
Diarrhea
Soggetto genere / forma Electronic books.
ISBN 1-61324-466-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Historical perspective -- Genetic organization -- Epidemiology -- Classification -- Risk factors -- Pathogenecity -- Symptoms -- Diagnosis -- BIII/NAP1/027 strain -- Treatment -- Prevention.
Record Nr. UNINA-9910456961503321
Kato Hideaki  
Hauppauge, N.Y., : Nova Science Publishers, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Autore Kato Hideaki
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, 2010
Descrizione fisica 1 online resource (62 p.)
Disciplina 616.9/31
Altri autori (Persone) KatoHaru
Collana Public health in the 21st century
Bacteriology research developments
Soggetto topico Clostridium diseases
Clostridium difficile
Diarrhea
ISBN 1-61324-466-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Historical perspective -- Genetic organization -- Epidemiology -- Classification -- Risk factors -- Pathogenecity -- Symptoms -- Diagnosis -- BIII/NAP1/027 strain -- Treatment -- Prevention.
Record Nr. UNINA-9910781675803321
Kato Hideaki  
Hauppauge, N.Y., : Nova Science Publishers, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Clostridum difficile-associated diarrhea [[electronic resource] /] / Hideaki Kato, [Haru Kato]
Autore Kato Hideaki
Pubbl/distr/stampa Hauppauge, N.Y., : Nova Science Publishers, 2010
Descrizione fisica 1 online resource (62 p.)
Disciplina 616.9/31
Altri autori (Persone) KatoHaru
Collana Public health in the 21st century
Bacteriology research developments
Soggetto topico Clostridium diseases
Clostridium difficile
Diarrhea
ISBN 1-61324-466-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Historical perspective -- Genetic organization -- Epidemiology -- Classification -- Risk factors -- Pathogenecity -- Symptoms -- Diagnosis -- BIII/NAP1/027 strain -- Treatment -- Prevention.
Record Nr. UNINA-9910808292103321
Kato Hideaki  
Hauppauge, N.Y., : Nova Science Publishers, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui