Info
- Utilizzare la checkbox di selezione a fianco di ciascun documento per attivare le funzionalità di stampa, invio email, download nei formati disponibili del (i) record.
Access to Non-Summary Clinical Trial Data for Research Purposes Under EU Law / / by Daria Kim
| Access to Non-Summary Clinical Trial Data for Research Purposes Under EU Law / / by Daria Kim |
| Autore | Kim Daria |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (310 pages) |
| Disciplina | 342.240662 |
| Collana | Munich Studies on Innovation and Competition |
| Soggetto topico |
Information technology - Law and legislation
Mass media - Law and legislation Medical laws and legislation Law - Europe Clinical medicine - Research Quantitative research IT Law, Media Law, Intellectual Property Medical Law European Law Clinical Research Data Analysis and Big Data |
| ISBN | 3-030-86778-1 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | PART ONE: Setting the Scene -- Introduction -- The Context and the Problem in Focus -- Secondary Analysis of Clinical Trial Data - A Primer -- PART TWO: Analysis de lege lata,- Legal Sources of Control over and Access to Clinical Trial Data under the EU Applicable Framework -- Implications of IPD Disclosure for Statutory Innovation Incentives PART THREE: Analysis de lege ferenda -- Defining the Intervention Logic of Access-To-Data Measures - A Problem Analysis -- Access to Clinical Trial Data as a Case on R&D Externalities - A Theoretical Framework -- IPD as a Research Resource - Exclusively Controlled or Readily Accessible? -- Evaluating Legislative Options -- Final Conclusions and the Outlook. |
| Record Nr. | UNINA-9910506380003321 |
Kim Daria
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Analysis of Data from Randomized Controlled Trials : A Practical Guide / / by Jos W.R. Twisk
| Analysis of Data from Randomized Controlled Trials : A Practical Guide / / by Jos W.R. Twisk |
| Autore | Twisk Jos W. R. <1962-> |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (167 pages) |
| Disciplina | 616.027 |
| Soggetto topico |
Statistics
Clinical medicine - Research Biometry Experimental design Statistical Theory and Methods Clinical Research Biostatistics Design of Experiments |
| ISBN |
9783030818654
3030818659 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Analysis of RCT data with one follow-up measurement -- Analysis of RCT data with more than one follow-up measurement -- Analysis of data from a cluster RCT -- Analysis of data from a cross-over trial -- Analysis of data from stepped wedge trials -- Analysis of data from N-of-1 trials -- Dichotomous outcomes -- What to do when only a baseline measurement is available -- Sample size calculations. |
| Record Nr. | UNINA-9910502594203321 |
|
Twisk Jos W. R. <1962->
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Bayesian Inference and Computation in Reliability and Survival Analysis [[electronic resource] /] / edited by Yuhlong Lio, Ding-Geng Chen, Hon Keung Tony Ng, Tzong-Ru Tsai
| Bayesian Inference and Computation in Reliability and Survival Analysis [[electronic resource] /] / edited by Yuhlong Lio, Ding-Geng Chen, Hon Keung Tony Ng, Tzong-Ru Tsai |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (367 pages) |
| Disciplina | 519.542 |
| Collana | Emerging Topics in Statistics and Biostatistics |
| Soggetto topico |
Statistics
Clinical medicine - Research Bayesian Inference Bayesian Network Clinical Research Estadística bayesiana |
| Soggetto genere / forma | Llibres electrònics |
| ISBN | 3-030-88658-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. A Bayesian Approach for Step-stress Accelerated Life-tests for One-shot Devices under Exponential Distributions -- 2. Bayesian Estimation of Stress-strength Parameter for Moran-Downton Bivariate Exponential Distribution under Progressive Type-II Censoring -- 3. Bayesian Computation in A Birnbaum-Saunders Reliability Model with Applications to Fatigue Data -- 4. A Competing Risks Model Based on A Two-parameter Exponential Family Distribution under Progressive Type-II Censoring -- 5. Bayesian Computations for Reliability Analysis in Dynamic Environments -- 6. Bayesian Analysis of Stochastic Processes in Reliability -- 7. Bayesian Analysis of A New Bivariate Wiener Degradation Process -- 8. Bayesian Estimation for Bivariate Gamma Processes with Copula -- 9. Review of Statistical Treatment for Oncology Dose Escalation Trial with Prolonged Evaluation Window or Fast Enrollment -- 10. A Bayesian Approach for the Analysis of Tumorigenicity Data from Sacrificial Experiments under Weibull Lifetimes -- 11. Bayesian Sensitivity Analysis in Survival and Longitudinal Trial with Missing Data -- 12. Bayesian Analysis for Clustered Data under A Semi-competing Risks Framework -- 13. Survival Analysis for the Inverse Gaussian Distribution: Natural Conjugate and Jeffrey’s Priors -- 14. Bayesian Inferences for Panel Count Data and Interval-censored Data with Nonparametric Modeling of the Baseline Functions -- 15. Bayesian Approach for Interval-censored Survival Data with Time-varying Coefficients -- 16. Bayesian Approach for Joint-modeling Longitudinal Data and Survival Data Simultaneously in Public Health Studies. |
| Record Nr. | UNISA-996485662503316 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
| ||
Bayesian Inference and Computation in Reliability and Survival Analysis / / edited by Yuhlong Lio, Ding-Geng Chen, Hon Keung Tony Ng, Tzong-Ru Tsai
| Bayesian Inference and Computation in Reliability and Survival Analysis / / edited by Yuhlong Lio, Ding-Geng Chen, Hon Keung Tony Ng, Tzong-Ru Tsai |
| Edizione | [1st ed. 2022.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
| Descrizione fisica | 1 online resource (367 pages) |
| Disciplina | 519.542 |
| Collana | Emerging Topics in Statistics and Biostatistics |
| Soggetto topico |
Statistics
Clinical medicine - Research Bayesian Inference Bayesian Network Clinical Research |
| ISBN | 3-030-88658-1 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. A Bayesian Approach for Step-stress Accelerated Life-tests for One-shot Devices under Exponential Distributions -- 2. Bayesian Estimation of Stress-strength Parameter for Moran-Downton Bivariate Exponential Distribution under Progressive Type-II Censoring -- 3. Bayesian Computation in A Birnbaum-Saunders Reliability Model with Applications to Fatigue Data -- 4. A Competing Risks Model Based on A Two-parameter Exponential Family Distribution under Progressive Type-II Censoring -- 5. Bayesian Computations for Reliability Analysis in Dynamic Environments -- 6. Bayesian Analysis of Stochastic Processes in Reliability -- 7. Bayesian Analysis of A New Bivariate Wiener Degradation Process -- 8. Bayesian Estimation for Bivariate Gamma Processes with Copula -- 9. Review of Statistical Treatment for Oncology Dose Escalation Trial with Prolonged Evaluation Window or Fast Enrollment -- 10. A Bayesian Approach for the Analysis of Tumorigenicity Data from Sacrificial Experiments under Weibull Lifetimes -- 11. Bayesian Sensitivity Analysis in Survival and Longitudinal Trial with Missing Data -- 12. Bayesian Analysis for Clustered Data under A Semi-competing Risks Framework -- 13. Survival Analysis for the Inverse Gaussian Distribution: Natural Conjugate and Jeffrey’s Priors -- 14. Bayesian Inferences for Panel Count Data and Interval-censored Data with Nonparametric Modeling of the Baseline Functions -- 15. Bayesian Approach for Interval-censored Survival Data with Time-varying Coefficients -- 16. Bayesian Approach for Joint-modeling Longitudinal Data and Survival Data Simultaneously in Public Health Studies. |
| Record Nr. | UNINA-9910586592203321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biomaterials and Neurodegenerative Disorders / / edited by Gaurav Kumar, Sumedha Mukherjee, Santosh Kumar
| Biomaterials and Neurodegenerative Disorders / / edited by Gaurav Kumar, Sumedha Mukherjee, Santosh Kumar |
| Autore | Kumar Gaurav |
| Edizione | [1st ed. 2025.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2025 |
| Descrizione fisica | 1 online resource (0 pages) |
| Disciplina | 660.6 |
| Altri autori (Persone) |
MukherjeeSumedha
KumarSantosh |
| Soggetto topico |
Biotechnology
Proteins Biomaterials Neurosciences Diagnosis Clinical medicine - Research Biomaterials-Proteins Neuroscience Clinical Research |
| ISBN |
9789819799596
9819799597 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | -- Chapter 1: Foundations of Biomaterials: Types, Evolution, and Medical Applications -- Chapter 2: Synthesis and Comprehensive Characterization of Neurocompatible Biomaterials -- Chapter 3: Neuro-Compatible Biomaterials: Pioneering Solutions for Brain and Nerve Disorders -- Chapter 4: Advanced Biomaterials in Neuroprotection: Innovations and Clinical Applications -- Chapter 5: Biomaterials for Neuroregeneration: Mechanisms and Therapeutic Applications -- Chapter 6: Approaches in Neuro-Compatible Biomaterial Designing for Neural Repair and Drug Delivery -- Chapter 7: Advancements in Biomaterials for Neuronal Tissue Regeneration: Applications and Future Prospects -- Chapter 8: Biomaterials in Cerebral Stroke Diagnosis and Therapeutics -- Chapter 9: Biomaterials in Clinical Trials & Clinical Applications -- Chapter 10:Intellectual Property Rights in Neuroprotective Biomaterials. |
| Record Nr. | UNINA-9910983040603321 |
|
Kumar Gaurav
|
||
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2025 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biostatistics in Biopharmaceutical Research and Development : Clinical Trial Analysis, Volume 2 / / edited by Ding-Geng Chen
| Biostatistics in Biopharmaceutical Research and Development : Clinical Trial Analysis, Volume 2 / / edited by Ding-Geng Chen |
| Autore | Chen Ding-Geng |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (522 pages) |
| Disciplina | 519.5 |
| Soggetto topico |
Statistics
Biometry Clinical medicine - Research Sampling (Statistics) Public health Biostatistics Clinical Research Methodology of Data Collection and Processing Survey Methodology Public Health |
| ISBN |
9783031659379
9783031659362 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Statistical Challenges in the Analysis of Biomarker Data -- 2. Evaluating Predictive Accuracy of Prognostic Model for Censored Time-to-Event Data Analysis in Clinical Trials -- Statistical Methods for Accommodating Immortal Time: A Selective Review and Comparison -- Variable selection for partially functional additive Cox Model with interval-censored failure time data -- A Bayesian proportional hazards model to predict patient recruitment in multicenter clinical trials -- GET MORE INFORMATION FROM RECURRENT EVENTS DATA -- Introduction to Patient Preference Studies -- Machine Learning for Precision Medicine and Humanized AI for Future Healthcare -- The Statistical Evaluation of Surrogate Endpoints in Clinical Trials -- Treatment Effect Estimation Using Data from Observational and Non-Randomized Studies -- Methods for Comparing Two Treatments for a Dichotomous Outcome for a Two-Period Design with Treatment Switching of Control Group Period 1 Non-Responders -- Regression-based estimation of optimal adaptive treatment strategies: Key methods -- Vaccine Disease-Prevention Efficacy Studies: Traditional Approaches and New Frontiers -- Covariate Adjustment in Analyzing Randomized Clinical Trials: Approaches, Software, and Application -- Joint correlated responses and feedback effect with time-dependent covariates -- Distributions and Their Approximations for P-Values. |
| Record Nr. | UNINA-9910919809503321 |
|
Chen Ding-Geng
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biostatistics in Biopharmaceutical Research and Development : Clinical Trial Design, Volume 1 / / edited by Ding-Geng Chen
| Biostatistics in Biopharmaceutical Research and Development : Clinical Trial Design, Volume 1 / / edited by Ding-Geng Chen |
| Autore | Chen Ding-Geng |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (355 pages) |
| Disciplina | 570.15195 |
| Soggetto topico |
Biometry
Clinical medicine - Research Public health Sampling (Statistics) Data mining Biostatistics Clinical Research Public Health Survey Methodology Data Mining and Knowledge Discovery |
| ISBN |
9783031659485
9783031659478 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bias and Randomization in Clinical Trials: 1980s – 2020s – 2060s -- The Markov Model for Survival Trials at 35 Years-Old -- Absolute Power Corrupts Absolutely: A Review of the Use of Unconditional Probabilities in the Planning of Clinical Trials -- Design of Clinical Trials with the Desirability of Outcome Ranking Methodology -- Benefit:Risk Assessments during Clinical Trials: A Prediction Approach Using the Desirability of Outcome Ranking (DOOR) -- The Power of Integration: How the 2-in-1 Clinical Trial Design is Changing the Future of Drug Development -- A Unified Bayesian Decision Rule-Based Approach for Bayesian Design of Clinical Trials Using Historical Data -- Group Sequential Design Under Non-proportional Hazards: Methodologies and Examples -- Multiple Testing in Group Sequential Design -- Plan per-protocol (PP) causal inference analysis addressing intercurrent events following the targeted learning roadmap -- Maximum Tolerated Imbalance Randomization: Theory and Practice -- Response-adaptive randomization designs based on optimal allocation proportion. |
| Record Nr. | UNINA-9910919814303321 |
|
Chen Ding-Geng
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Biostatistics With 'R': A Guide for Medical Doctors / / by Marco Moscarelli
| Biostatistics With 'R': A Guide for Medical Doctors / / by Marco Moscarelli |
| Autore | Moscarelli Marco |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (248 pages) |
| Disciplina |
610
610.727 |
| Soggetto topico |
Medicine
Biometry Clinical medicine - Research Clinical Medicine Biostatistics Clinical Research |
| ISBN |
9783031330735
3031330730 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. Introduction -- Chapter 2. How “R” works -- Chapter 3. Exploratory data analysis in “R” -- Chapter 4. Data types in “R” -- Chapter 5. Data distribution -- Chapter 6. Precision, accuracy, indices of central tendency -- Chapter 7. Correlation -- Chapter 8. Hypothesis testing -- Chapter 9. Linear regression -- Chapter 10. Logistic regression -- Chapter 11. Survival analysis -- Chapter 12. Propensity score matching. |
| Record Nr. | UNINA-9910739412103321 |
|
Moscarelli Marco
|
||
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Charcot's Lesson : Learning Scientific Reasoning and Clinical Methodology / / by Francesco Brigo
| Charcot's Lesson : Learning Scientific Reasoning and Clinical Methodology / / by Francesco Brigo |
| Autore | Brigo Francesco |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (132 pages) |
| Disciplina | 616 |
| Collana | Neurocultural Health and Wellbeing |
| Soggetto topico |
Neurology
Clinical medicine - Research Medicine Medicine - History Clinical Research Clinical Medicine History of Medicine |
| ISBN | 3-031-71221-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Preface -- Part I. Methodological Aspects -- 1. Charcot, the Master: Who Was He and What Can We Learn from Him? -- 2. I Can’t Believe My Eyes (And Actually I Should Not)! Don’t Get Confounded by Confounders! -- 3. What to Expect from Experience? -- 4. "The Theory Is Good, but That Doesn't Prevent Reality from Existing" -- 5. Induction and Deduction: Taken in the Loop -- 6. Nothing but a Domino Effect: Is Causation Really That Simple? -- 7. Let’s Think About It! Metacognition of Clinical Thinking -- 8. The Razor That Does Not Split Hairs -- 9. Useless and Yet So Useful: Why We Should Keep Visiting Our Patients -- 10. Step by Step: Approach to the Diagnosis -- 11. Not All Errors Are Created Equally: Biological Variability and Systematic Errors (Bias) -- 12. I’m Never Wrong! Logical Fallacies and Cognitive Errors -- 13. Evidence Is Much but Not All: Rethinking Evidence-Based Medicine -- 14. How to Critically Appraise a Medical Article -- Part II. Theory and Practice -- 15. Critical Appraisal of a Therapy Article: Randomized Controlled Trial -- 16. Critical Appraisal of a Therapy Article: Non-Randomized Controlled Study and Uncontrolled Study -- 17. Critical Appraisal of a Diagnosis Article -- Part III. Epilogue -- 18. Beware of Masters (Yes, Even of Charcot)! The Importance of Distrusting Everything and Everyone -- Index. |
| Record Nr. | UNINA-9910900172503321 |
|
Brigo Francesco
|
||
| Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Clinical Chinese Named Entity Recognition in Natural Language Processing / / by Shuli Guo, Lina Han, Wentao Yang
| Clinical Chinese Named Entity Recognition in Natural Language Processing / / by Shuli Guo, Lina Han, Wentao Yang |
| Autore | Guo Shuli |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (103 pages) |
| Disciplina | 610.285 |
| Soggetto topico |
Machine learning
Computational linguistics Clinical medicine - Research Image processing - Digital techniques Computer vision Machine Learning Computational Linguistics Clinical Research Computer Imaging, Vision, Pattern Recognition and Graphics |
| ISBN | 981-9926-65-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Theoretical Basis -- Related Existed Models -- Medical Named Entity Recognition Models with the Attention Distraction Mechanism -- Transformer Entity Automatic Extraction Models in Multi-Layer Soft Location Matching Format -- Medical Named Entity Recognition Modelling based on Remote Monitoring and Denoising. |
| Record Nr. | UNINA-9910739465403321 |
|
Guo Shuli
|
||
| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
