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Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma
Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma
Autore Gemma Akihiko
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (122 pages)
Disciplina 616.2
Soggetto topico Respiratory organs - Diseases
Medical genetics
Diseases - Causes and theories of causation
Oncology
Pharmacology
Genetics - Research
Pneumology
Clinical Genetics
Pathogenesis
Genetics Research
ISBN 9789819734467
9789819734450
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I Understanding Drug-Induced Lung Injuries -- 1 Understanding Drug-Induced Lung Injuries -- Part 2 Actual Practice in Drug-Induced Lung Injuries of Each Drug -- 2 EGFR inhibitors (gefitinib, erlotinib, afatinib, osimertinib) -- 3 Anti-EGFR antibodies (cetuximab, panitumumab, necitumumab) -- 4 mTOR inhibitors (temsirolimus, everolimus) -- 5 Proteasome inhibitor (bortezomib) -- 6 Immune checkpoint inhibitors (nivolumab, pembrolizumab, atezolizumab, durvalumab) -- 7 Neoangiogenesis inhibitors (sunitinib, sorafenib, bevacizumab) -- 8 Other molecular targeted drugs (crizotinib, alectinib, etc.) -- 9 Antibody-drug conjugates (ADC) (trastuzumab emtansine, trastuzumab deruxtecan) -- 10 Anti-cancer drugs (TS-1, taxanes, CPT-11, platinum-containing drugs, etc.).
Record Nr. UNINA-9910878983003321
Gemma Akihiko  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag
Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag
Autore Nieschlag Eberhard
Edizione [4th ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (840 pages)
Disciplina 616.6/5
616.65
Altri autori (Persone) BehreHermann M
KlieschSabine
NieschlagSusan
Soggetto topico Reproductive health
Urology
Endocrinology
Dermatology
Medical genetics
Reproductive Medicine
Clinical Genetics
ISBN 3-031-31574-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Scope and Goals of Andrology -- Part I. Physiologic Basis -- 2. Physiology of testicular function -- 3. Physiology of sperm maturation and fertilization -- Part II. Classification and Diagnosis of Andrological Disorders -- 4. Classification of andrological disorders -- 5. Anamnesis and Physical Examination -- 6. Ultrasound imaging in andrology -- 7. Endocrine Laboratory Diagnosis -- 8. Cytogenetic and molecular genetic diagnostics -- 9. Semen analysis -- 10. Sperm quality and sperm function tests -- 11. Biopsy and histology of the testis -- Part III. Clinics in Andrology: Secondary Hypogonadism -- 12. Congenital hypogonadotropic hypogonadism of hypothalamic origin -- 13. Congenital hypogonadotropic hypogonadism of pituitary origin and rare syndromes with central hypogonadism -- 14. Delayed puberty in boys -- 15. Pituitary hypogonadism, hyperprolactinemia, and gonadotropin-producing tumors -- Part IV. Clinics in Andrology: Primary Hypogonadism (Disorders at the Testicular Level) -- 16. Anorchia and Polyorchidism -- 17. Undescended testes -- 18. Varicocele -- 19. Orchitis -- 20. Disorders of spermatogenesis and spermiogenesis -- 21. Klinefelter syndrome -- 22. XX male and XYY karyotype -- 23 Structural chromosomal changes -- 24. Testicular tumors -- 25. Senescence and late-onset hypogonadism -- Part V. Clinics in Andrology: Diseases of Seminal Ducts and Accessory Sex Organs -- 26. Infections and inflammation of the seminal ducts and accessory sex glands -- 27. Obstructions of the seminal ducts, cystic fibrosis and congenital aplasia of the ductus deferens -- 28. Immunologically induced infertility -- 29. Andrologically relevant changes in the external genitals -- 30. Disorders of erection, cohabitation and ejaculation -- Part VI. Clinics in Andrology: Disorders of Sexual Differentiation and Androgen Target Organs -- 31. Variants of sex development -- 32. Gynecomastia -- 33. Male androgenetic alopecia -- Part VII. Clinics in Andrology: Disorders of Reproductive Health caused by Environmental and Systemic Diseases -- 34. Testicular dysfunction in systemic diseases -- 35. Environmental Influences on Male Reproductive Health -- Part VIII. Andrological Therapy -- 36. Therapy with testosterone -- 37. Abuse of anabolic androgenic steroids (AAS) for doping -- 38. Treatment of hypogonadism of hypothalamic or pituitary origin -- 39. Therapeutic attempts in idiopathic infertility -- 40. Gynecology relevant to andrology -- 41. Assisted fertilization -- 42. Cryopreservation of human sperm and testicular germ cell tissue for fertility reserve -- Part IX. Sexual Health -- 43. Sexual Medicine and Andrology -- 44. Involuntary Childlessness from the Perspective of Sexual Medicine -- Part X. Male Contraception -- 45. Male contribution to contraception -- 46. Vasectomy -- 47. Approaches to hormonal male contraception -- 48. Non-hormonal Approaches to Male Contraception -- Part XI. Law and Ethics in Reproductive Medicine -- 49. Legal regulations in Andrology and Reproductive Medicine -- 50. Ethical criteria of reproductive medicine. .
Record Nr. UNINA-9910755083003321
Nieschlag Eberhard  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Lo trovi qui: Univ. Federico II
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Atlas of Inherited Retinal Diseases / / edited by Stephen H. Tsang, Tarun Sharma, Vlad Diaconita
Atlas of Inherited Retinal Diseases / / edited by Stephen H. Tsang, Tarun Sharma, Vlad Diaconita
Autore Tsang Stephen H
Edizione [2nd ed. 2025.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
Descrizione fisica 1 online resource (433 pages)
Disciplina 617.735
Altri autori (Persone) SharmaTarun
DiaconitaVlad
Collana Advances in Experimental Medicine and Biology
Soggetto topico Ophthalmology
Medical genetics
Genetics
Clinical Genetics
Medical Genetics
Genetics and Genomics
ISBN 3-031-72230-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1 Retinal Histology and Anatomical Landmarks -- Chapter 2 Fluorescein Angiography -- Chapter 3 Optical Coherence Tomography -- Chapter 4 Fundus Autofluorescence -- Chapter 5 ERG -- Chapter 6 Electrooculography -- Chapter 7 Glossary of Relevant Genetic and MolecularCell Biology -- Chapter 8 X-linked Retinitis Pigmentosa -- Chapter 9 X-linked Choroideremia -- Chapter 10 X-linked Juvenile Retinoschisis -- Chapter 11 X-linked Ocular Albinism -- Chapter 12 Progressive Cone Dystrophy and Cone-Rod Dystrophy -- Chapter 13 Congenital Stationary Night Blindness -- Chapter 14 Blue Cone Monochromatism -- Chapter 15 Autosomal Dominant Retinitis Pigmentosa -- Chapter 16 Best Vitelliform Macular Dystrophy -- Chapter 17 Pattern Dystrophy -- Chapter 18 Doyne Honeycomb Retinal Dystrophy (Malattia Leventinese, Autosomal Dominant Drusen) -- Chapter 19 Occult Macular Dystrophy -- Chapter 20 Sorsby Pseudoinflammatory Fundus Dystrophy -- Chapter 21 North Carolina Macular Dystrophy -- Chapter 22 Pigmented Paravenous Chorioretinal Atrophy (PPCRA) -- Chapter 23 Late-Onset Retinal Degeneration -- Chapter 24 Achromatopsia (Rod Monochromatism) -- Chapter 25 Retinitis Pigmentosa (Non-syndromic) -- Chapter 26 Leber Congenital Amaurosis -- Chapter 27 Stargardt Disease -- Chapter 28 Enhanced S-Cone Syndrome (Goldmann-Favre Syndrome) -- Chapter 29 Best Vitelliform Macular Dystrophy -- Chapter 30 Mitochondrial Disorder Kearns-Sayre Syndrome -- Chapter 31 MIDD -- Chapter 32 Usher Syndrome -- Chapter 33 Bardet-Biedl Syndrome -- Chapter 34 Senior-Loken Syndrome -- Chapter 35 Alstrom Syndrome. Chapter 36 Sjogren-Larsson Syndrome -- Chapter 37 Inborn Errors of Metabolism Gyrate Atrophy -- Chapter 38 Pseudoxanthoma Elasticum -- Chapter 39 Refsum Disease -- Chapter 40 Bietti -- Chapter 41 Alport Syndrome -- Chapter 42 N - Stickler Syndrome -- Chapter 43 N - OTX2 Syndrome -- Chapter 44 VHL -- Chapter 45 Tuberous Sclerosis -- Chapter 46 Neurofibromatosis -- Chapter 47 Rubella Retinopathy -- Chapter 48 Syphilis -- Chapter 49 AIR -- Chapter 50 Drug-Induced Retinal Toxicity -- Chapter 51 Non-Infectious Uveitis -- Chapter 52 Diffuse Unilateral Subacute Neuroretinitis (DUSN) -- Chapter 53 CSCR -- Chapter 54 Pathologic Myopia -- Chapter 55 A Practical Approach to Retinal Dystrophies -- Chapter 56 Genetic Testing For Inherited Retinal Dystrophy -- Chapter 57 Genetic Reports -- Chapter 58 The genetic basis of IRDS and the role of genetic testing -- Chapter 59 Seeing Stars The Gene Therapy Revolution -- Chapter 60 Mutation Specific Treatments for Inherited Retinal Diseases -- Chapter 61 Global Treatment Approaches Part 1 Neuroprotection and Stem Cell Therapy -- Chapter 62 Global Treatment Approaches Part 2 Optogenetics and Retinal Implants.
Record Nr. UNINA-9911018751303321
Tsang Stephen H  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
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Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville
Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (173 illus., 102 illus. in color. eReference.)
Disciplina 579.26
Soggetto topico Medical genetics
Bacteria
Medicine - Research
Biology - Research
Clinical Genetics
Biomedical Research
ISBN 3-319-41986-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bacteriophage Biology -- History of Bacteriophages -- Bacteriophage Technology -- Agriculture, Food and Environmental Use of Bacteriophages -- Therapeutic Use of Bacteriophages.
Record Nr. UNINA-9910483262703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Materiale a stampa
Lo trovi qui: Univ. Federico II
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Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen
Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (179 pages)
Disciplina 616.02774
Collana Cell Biology and Translational Medicine
Soggetto topico Stem cells
Regenerative medicine
Medical genetics
Biotechnology
Stem Cell Biology
Regenerative Medicine and Tissue Engineering
Clinical Genetics
Chemical Bioengineering
ISBN 3-030-17589-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Therapeutic Cardiac Patches for Repairing the Myocardium -- Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead -- CRISPR/Cas9 for Sickle Cell Disease: Applications, Future possibilities, and Challenges -- Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation -- Cellular complexity at the interface: Challenges in enthesis tissue engineering -- Induced Pluripotent Stem Cells in Disease Modelling and Regeneration -- Stem cells for the oromaxillofacial area: Could they be a promising source for regeneration in dentistry? -- Stem Cells Derived from Dental Tissues -- A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation -- Mesenchymal Stem Cells as Regulators of Carcinogenesis.
Record Nr. UNINA-9910337943603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Materiale a stampa
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Cerebrotendinous Xanthomatosis : A Treatable Rare Neurometabolic Disorder / / edited by Antonio Federico, Andrea E. DeBarber, Tzipora C. Falik-Zaccai, Hidde H. Huidekoper, Robert D. Steiner
Cerebrotendinous Xanthomatosis : A Treatable Rare Neurometabolic Disorder / / edited by Antonio Federico, Andrea E. DeBarber, Tzipora C. Falik-Zaccai, Hidde H. Huidekoper, Robert D. Steiner
Autore Federico Antonio
Edizione [1st ed. 2025.]
Pubbl/distr/stampa Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
Descrizione fisica 1 online resource (458 pages)
Disciplina 616.39
Altri autori (Persone) DeBarberAndrea E
Falik-ZaccaiTzipora C
HuidekoperHidde H
SteinerRobert D
Collana Medicine Series
Soggetto topico Neurology
Pediatrics
Medical genetics
Internal medicine
Clinical Genetics
Internal Medicine
ISBN 3-031-92526-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Cerebrotendinous Xantomatosis (CTX): general review and history of the research on its pathogenesis and therapy -- 2. CerebroTendinous Xanthomatosis (CTX) in Italy -- 3. CTX in The Netherlands -- 4. CTX in Brazil -- 5. Cerebrotendinous xanthomatosis in France -- 6.CTX in Japan -- 7. Cerebrotendinous Xanthomatosis: remaining challenges and the need for international collaboration -- 8. Genetics of CTX -- 9. General Overview Biochemistry with Focus on Clinical Laboratory -- 10. Focus on CTX Cases Identified with Atypical Biochemistry -- 11.Cholestanol accumulation in the brain and eye in cerebrotendinous xanthomatosis -- 12. Role of Bile Acid Pathway Intermediates in Pathology of CTX -- 13. Overview of Neuroimaging in Cerebrotendinous Xanthomatosis Diagnosis -- 14. Novel tools for neuroimaging in cerebrotendinous xanthomatosis -- 15. Epidemiology of Cerebrotendinous Xanthomatosis -- 16. Chenodeoxycholic acid treatment in the italian cohort of CTX patients -- 17. Long-term treatment effect in CTX depends on age at treatment -- 18.Can we improve outcomes? Lessons taken from the Israeli CTX Cohort -- 19. Treatment during Pregnancy in CTX -- 20. Cerebrotendinous xanthomatosis (CTX) presenting as neonatal cholestasis, its diagnosis and treatment with primary bile acids, cholic and chenodeoxycholic acids -- 21. Cholic acid treatment in adults with cerebrotendinous xanthomatosis -- 22. Gene Therapy for CTX -- 23. CTX Pediatric presentation -- 24. Ophthalmic manifestation in CTX -- 25. Update on Newborn Screening for Cerebrotendinous Xanthomatosis -- 26. Early treatment improves outcomes for patients with cerebrotendinous xanthomatosis (CTX) -- 27. Cerebrotendinous Xanthomatosis Patient and Family Opinions and International CTX Patient Advocacy.
Record Nr. UNINA-9911034962703321
Federico Antonio  
Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2025
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Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan
Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan
Autore Ratan Simmi K
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (763 pages)
Disciplina 618.928583
Soggetto topico Pediatrics
Children - Surgery
Hormones
Medical genetics
Chromosomes
Pediatric Surgery
Hormone
Clinical Genetics
ISBN 9789819716395
9789819716388
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Anatomical differentiation and development of gonads -- Molecular regulation of sexual differentiation -- Hormonal regulation during gonadal development -- rain imprinting during gonadal differentiation -- Gender identity and role -- Gender dysphoria in DSD children -- Metaanalysis and current literature on gender identity disorders -- Psychopathological and psychiatric co-morbidities ingender dysphoria -- Legal aspects of DSD Indian & International scenario -- E volution and history of landmark judgements for DSD -- Terminology and clinical evaluation in the Diagnosis of DSD -- Cytogenetic and Molecular Genetic investigations in DSD -- Imaging and Endoscopy in the Diagnosis of DSD -- Endocrine profiling in diagnosis -- Pathology of DSD.
Record Nr. UNINA-9910906193303321
Ratan Simmi K  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman
Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman
Autore Abdel Rahman Anas M
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (349 pages)
Disciplina 616.042
Soggetto topico Medical genetics
Metabolism - Disorders
Biochemistry
Metabolism
Cytology
Medicine
Bioinformatics
Clinical Genetics
Metabolic Disease
Metabolic Pathways
Clinical Medicine
ISBN 981-9951-62-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. The advanced technology and clinical application in metabolomics -- Chapter 2. Mass Spectrometry-Based Metabolomics for the Clinical Laboratory -- Chapter 3. Metabolomics: a pipeline for biomarker discovery in genetic diseases -- Chapter 4. Bioinformatics Tools for Clinical Metabolomics -- Chapter 5. Untargeted Metabolomics in Newborn Screening -- Chapter 6. Untargeted Metabolomics, Targeted Care: The Clinical Utilities of Bedside Metabolomics -- Chapter 7. Metabolomics in the Study of Human Mitochondrial Diseases -- Chapter 8. Metabolomics of Rare endocrine, genetic disease- A focus on the Pituitary gland -- Chapter 9. Metabolomics and genetics of rare endocrine disease - adrenal, parathyroid glands, and cystic fibrosis -- Chapter 10. Metabolomics role in personalized medicine: An update -- Chapter 11. Lipidomic Profiling in Clinical Practice Using LC-MS -- Chapter 12. Bringing Human Serum Lipidomics to the Forefront of Clinical Practice: Two Clinical Diagnosis Success Stories -- Chapter 13. LC-MS based population metabolomics: a mini-review of recent studies and challenges from sample collection to data processing -- Chapter 14. Metabolomics and transcriptomics approach to understand the pathophysiology of interstitial lung disease -- Chapter 15. Transferring metabolomics to portable diagnostic devices- Trending in biosensors.
Record Nr. UNINA-9910746962103321
Abdel Rahman Anas M  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
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DNA Know Thyself : Living in a DNA World / / by Ray J Rose
DNA Know Thyself : Living in a DNA World / / by Ray J Rose
Autore Rose Ray J
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (185 pages)
Disciplina 616.042
Soggetto topico Medical genetics
Molecular genetics
Developmental genetics
Biotechnology
Genetics
Medical Genetics
Clinical Genetics
Molecular Genetics
Developmental Genetics
Genetics and Genomics
ISBN 9789819783816
9789819783809
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Genesis of DNA and cells like ours -- DNA and the diversity of life sustains us and our environment -- The evolving story of DNA, genes and genomes -- We come from single cells – from gene regulation to stem cells -- The cell division cycle and the biology of cancer -- Generation upon generation -- DNA and ageing -- RNA and DNA viruses reproduce in cells -- DNA and the rise of modern biotechnology -- DNA and food and nutrition for 10 billion people -- DNA and the environment -- Gene therapy for human disease -- Synthetic biology – a new frontier -- We have the whole world in our hands.
Record Nr. UNINA-9910908371703321
Rose Ray J  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (IX, 272 p. 1 illus.)
Disciplina 615.19
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Ophthalmology
Pharmaceutical chemistry
Medical genetics
Medicinal Chemistry
Pharmaceutics
Clinical Genetics
ISBN 3-030-56619-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. .
Record Nr. UNINA-9910420948603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
Lo trovi qui: Univ. Federico II
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