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Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma
| Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma |
| Autore | Gemma Akihiko |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (122 pages) |
| Disciplina | 616.2 |
| Soggetto topico |
Respiratory organs - Diseases
Medical genetics Diseases - Causes and theories of causation Oncology Pharmacology Genetics - Research Pneumology Clinical Genetics Pathogenesis Genetics Research |
| ISBN |
9789819734467
9789819734450 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Part I Understanding Drug-Induced Lung Injuries -- 1 Understanding Drug-Induced Lung Injuries -- Part 2 Actual Practice in Drug-Induced Lung Injuries of Each Drug -- 2 EGFR inhibitors (gefitinib, erlotinib, afatinib, osimertinib) -- 3 Anti-EGFR antibodies (cetuximab, panitumumab, necitumumab) -- 4 mTOR inhibitors (temsirolimus, everolimus) -- 5 Proteasome inhibitor (bortezomib) -- 6 Immune checkpoint inhibitors (nivolumab, pembrolizumab, atezolizumab, durvalumab) -- 7 Neoangiogenesis inhibitors (sunitinib, sorafenib, bevacizumab) -- 8 Other molecular targeted drugs (crizotinib, alectinib, etc.) -- 9 Antibody-drug conjugates (ADC) (trastuzumab emtansine, trastuzumab deruxtecan) -- 10 Anti-cancer drugs (TS-1, taxanes, CPT-11, platinum-containing drugs, etc.). |
| Record Nr. | UNINA-9910878983003321 |
Gemma Akihiko
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag
| Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag |
| Autore | Nieschlag Eberhard |
| Edizione | [4th ed. 2023.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (840 pages) |
| Disciplina |
616.6/5
616.65 |
| Altri autori (Persone) |
BehreHermann M
KlieschSabine NieschlagSusan |
| Soggetto topico |
Reproductive health
Urology Endocrinology Dermatology Medical genetics Reproductive Medicine Clinical Genetics |
| ISBN | 3-031-31574-X |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | 1. Scope and Goals of Andrology -- Part I. Physiologic Basis -- 2. Physiology of testicular function -- 3. Physiology of sperm maturation and fertilization -- Part II. Classification and Diagnosis of Andrological Disorders -- 4. Classification of andrological disorders -- 5. Anamnesis and Physical Examination -- 6. Ultrasound imaging in andrology -- 7. Endocrine Laboratory Diagnosis -- 8. Cytogenetic and molecular genetic diagnostics -- 9. Semen analysis -- 10. Sperm quality and sperm function tests -- 11. Biopsy and histology of the testis -- Part III. Clinics in Andrology: Secondary Hypogonadism -- 12. Congenital hypogonadotropic hypogonadism of hypothalamic origin -- 13. Congenital hypogonadotropic hypogonadism of pituitary origin and rare syndromes with central hypogonadism -- 14. Delayed puberty in boys -- 15. Pituitary hypogonadism, hyperprolactinemia, and gonadotropin-producing tumors -- Part IV. Clinics in Andrology: Primary Hypogonadism (Disorders at the Testicular Level) -- 16. Anorchia and Polyorchidism -- 17. Undescended testes -- 18. Varicocele -- 19. Orchitis -- 20. Disorders of spermatogenesis and spermiogenesis -- 21. Klinefelter syndrome -- 22. XX male and XYY karyotype -- 23 Structural chromosomal changes -- 24. Testicular tumors -- 25. Senescence and late-onset hypogonadism -- Part V. Clinics in Andrology: Diseases of Seminal Ducts and Accessory Sex Organs -- 26. Infections and inflammation of the seminal ducts and accessory sex glands -- 27. Obstructions of the seminal ducts, cystic fibrosis and congenital aplasia of the ductus deferens -- 28. Immunologically induced infertility -- 29. Andrologically relevant changes in the external genitals -- 30. Disorders of erection, cohabitation and ejaculation -- Part VI. Clinics in Andrology: Disorders of Sexual Differentiation and Androgen Target Organs -- 31. Variants of sex development -- 32. Gynecomastia -- 33. Male androgenetic alopecia -- Part VII. Clinics in Andrology: Disorders of Reproductive Health caused by Environmental and Systemic Diseases -- 34. Testicular dysfunction in systemic diseases -- 35. Environmental Influences on Male Reproductive Health -- Part VIII. Andrological Therapy -- 36. Therapy with testosterone -- 37. Abuse of anabolic androgenic steroids (AAS) for doping -- 38. Treatment of hypogonadism of hypothalamic or pituitary origin -- 39. Therapeutic attempts in idiopathic infertility -- 40. Gynecology relevant to andrology -- 41. Assisted fertilization -- 42. Cryopreservation of human sperm and testicular germ cell tissue for fertility reserve -- Part IX. Sexual Health -- 43. Sexual Medicine and Andrology -- 44. Involuntary Childlessness from the Perspective of Sexual Medicine -- Part X. Male Contraception -- 45. Male contribution to contraception -- 46. Vasectomy -- 47. Approaches to hormonal male contraception -- 48. Non-hormonal Approaches to Male Contraception -- Part XI. Law and Ethics in Reproductive Medicine -- 49. Legal regulations in Andrology and Reproductive Medicine -- 50. Ethical criteria of reproductive medicine. . |
| Record Nr. | UNINA-9910755083003321 |
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Nieschlag Eberhard
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| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville
| Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 |
| Descrizione fisica | 1 online resource (173 illus., 102 illus. in color. eReference.) |
| Disciplina | 579.26 |
| Soggetto topico |
Medical genetics
Bacteria Medicine - Research Biology - Research Clinical Genetics Biomedical Research |
| ISBN | 3-319-41986-2 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Bacteriophage Biology -- History of Bacteriophages -- Bacteriophage Technology -- Agriculture, Food and Environmental Use of Bacteriophages -- Therapeutic Use of Bacteriophages. |
| Record Nr. | UNINA-9910483262703321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen
| Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen |
| Edizione | [1st ed. 2019.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
| Descrizione fisica | 1 online resource (179 pages) |
| Disciplina | 616.02774 |
| Collana | Cell Biology and Translational Medicine |
| Soggetto topico |
Stem cells
Regenerative medicine Medical genetics Biotechnology Stem Cell Biology Regenerative Medicine and Tissue Engineering Clinical Genetics Chemical Bioengineering |
| ISBN | 3-030-17589-8 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Therapeutic Cardiac Patches for Repairing the Myocardium -- Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead -- CRISPR/Cas9 for Sickle Cell Disease: Applications, Future possibilities, and Challenges -- Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation -- Cellular complexity at the interface: Challenges in enthesis tissue engineering -- Induced Pluripotent Stem Cells in Disease Modelling and Regeneration -- Stem cells for the oromaxillofacial area: Could they be a promising source for regeneration in dentistry? -- Stem Cells Derived from Dental Tissues -- A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation -- Mesenchymal Stem Cells as Regulators of Carcinogenesis. |
| Record Nr. | UNINA-9910337943603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan
| Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan |
| Autore | Ratan Simmi K |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (763 pages) |
| Disciplina | 618.928583 |
| Soggetto topico |
Pediatrics
Children - Surgery Hormones Medical genetics Chromosomes Pediatric Surgery Hormone Clinical Genetics |
| ISBN |
9789819716395
9789819716388 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Anatomical differentiation and development of gonads -- Molecular regulation of sexual differentiation -- Hormonal regulation during gonadal development -- rain imprinting during gonadal differentiation -- Gender identity and role -- Gender dysphoria in DSD children -- Metaanalysis and current literature on gender identity disorders -- Psychopathological and psychiatric co-morbidities ingender dysphoria -- Legal aspects of DSD Indian & International scenario -- E volution and history of landmark judgements for DSD -- Terminology and clinical evaluation in the Diagnosis of DSD -- Cytogenetic and Molecular Genetic investigations in DSD -- Imaging and Endoscopy in the Diagnosis of DSD -- Endocrine profiling in diagnosis -- Pathology of DSD. |
| Record Nr. | UNINA-9910906193303321 |
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Ratan Simmi K
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman
| Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman |
| Autore | Abdel Rahman Anas M |
| Edizione | [1st ed. 2023.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
| Descrizione fisica | 1 online resource (349 pages) |
| Disciplina | 616.042 |
| Soggetto topico |
Medical genetics
Metabolism - Disorders Biochemistry Metabolism Cytology Medicine Bioinformatics Clinical Genetics Metabolic Disease Metabolic Pathways Clinical Medicine |
| ISBN | 981-9951-62-3 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chapter 1. The advanced technology and clinical application in metabolomics -- Chapter 2. Mass Spectrometry-Based Metabolomics for the Clinical Laboratory -- Chapter 3. Metabolomics: a pipeline for biomarker discovery in genetic diseases -- Chapter 4. Bioinformatics Tools for Clinical Metabolomics -- Chapter 5. Untargeted Metabolomics in Newborn Screening -- Chapter 6. Untargeted Metabolomics, Targeted Care: The Clinical Utilities of Bedside Metabolomics -- Chapter 7. Metabolomics in the Study of Human Mitochondrial Diseases -- Chapter 8. Metabolomics of Rare endocrine, genetic disease- A focus on the Pituitary gland -- Chapter 9. Metabolomics and genetics of rare endocrine disease - adrenal, parathyroid glands, and cystic fibrosis -- Chapter 10. Metabolomics role in personalized medicine: An update -- Chapter 11. Lipidomic Profiling in Clinical Practice Using LC-MS -- Chapter 12. Bringing Human Serum Lipidomics to the Forefront of Clinical Practice: Two Clinical Diagnosis Success Stories -- Chapter 13. LC-MS based population metabolomics: a mini-review of recent studies and challenges from sample collection to data processing -- Chapter 14. Metabolomics and transcriptomics approach to understand the pathophysiology of interstitial lung disease -- Chapter 15. Transferring metabolomics to portable diagnostic devices- Trending in biosensors. |
| Record Nr. | UNINA-9910746962103321 |
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Abdel Rahman Anas M
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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DNA Know Thyself : Living in a DNA World / / by Ray J Rose
| DNA Know Thyself : Living in a DNA World / / by Ray J Rose |
| Autore | Rose Ray J |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (185 pages) |
| Disciplina | 616.042 |
| Soggetto topico |
Medical genetics
Molecular genetics Developmental genetics Biotechnology Genetics Medical Genetics Clinical Genetics Molecular Genetics Developmental Genetics Genetics and Genomics |
| ISBN |
9789819783816
9789819783809 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Genesis of DNA and cells like ours -- DNA and the diversity of life sustains us and our environment -- The evolving story of DNA, genes and genomes -- We come from single cells – from gene regulation to stem cells -- The cell division cycle and the biology of cancer -- Generation upon generation -- DNA and ageing -- RNA and DNA viruses reproduce in cells -- DNA and the rise of modern biotechnology -- DNA and food and nutrition for 10 billion people -- DNA and the environment -- Gene therapy for human disease -- Synthetic biology – a new frontier -- We have the whole world in our hands. |
| Record Nr. | UNINA-9910908371703321 |
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Rose Ray J
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
| Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 |
| Descrizione fisica | 1 online resource (IX, 272 p. 1 illus.) |
| Disciplina | 615.19 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Ophthalmology Pharmaceutical chemistry Medical genetics Medicinal Chemistry Pharmaceutics Clinical Genetics |
| ISBN | 3-030-56619-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. . |
| Record Nr. | UNINA-9910420948603321 |
| Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi
| Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi |
| Edizione | [1st ed. 2020.] |
| Pubbl/distr/stampa | Springer International Publishing, 2020 |
| Descrizione fisica | 1 online resource (IX, 272 p. 1 illus.) |
| Disciplina | 615.19 |
| Collana | Topics in Medicinal Chemistry |
| Soggetto topico |
Medicinal chemistry
Ophthalmology Pharmaceutical chemistry Medical genetics Medicinal Chemistry Pharmaceutics Clinical Genetics |
| ISBN | 3-030-56619-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. . |
| Record Nr. | UNINA-9910863166203321 |
| Springer International Publishing, 2020 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Gastroenterology and Hepatology : Bench to Bedside / / edited by Gourdas Choudhuri, Anil C Anand, P Piramanayagam
| Gastroenterology and Hepatology : Bench to Bedside / / edited by Gourdas Choudhuri, Anil C Anand, P Piramanayagam |
| Autore | Choudhuri Gourdas |
| Edizione | [1st ed. 2024.] |
| Pubbl/distr/stampa | Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 |
| Descrizione fisica | 1 online resource (0 pages) |
| Disciplina | 616.33 |
| Altri autori (Persone) |
AnandAnil C
PiramanayagamP |
| Soggetto topico |
Diagnosis
Internal medicine Gastrointestinal system Medical genetics Internal Medicine Gastrointestinal System Clinical Genetics |
| ISBN | 981-9992-87-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Intro -- Foreword -- Acknowledgments -- Introduction -- Contents -- Chapter 1: Esophagus -- 1.1 Lower Esophageal Sphincter -- 1.1.1 Anatomy -- 1.1.2 Embryology -- 1.1.3 Physiology -- 1.2 Wall Layer of the Esophagus -- 1.3 Esophageal Constrictions -- 1.4 Blood Supply of the Esophagus -- 1.5 Portosystemic Anastomosis -- 1.6 Lymphatic Drainage of Esophagus -- 1.7 Esophageal Rings -- 1.7.1 A Ring -- 1.7.2 B Ring -- 1.7.3 Corrugated Ringed Esophagus -- 1.8 Esophageal Webs -- 1.9 Esophagus in Portal Hypertension -- 1.9.1 Changes in Portal Hypertension -- 1.10 Tracheo-Esophageal Fistula -- 1.10.1 Diagnosis -- 1.10.2 Treatment -- 1.11 Transient Lower Esophageal Sphincter Relaxation -- 1.11.1 Definition -- 1.11.2 Physiology -- 1.11.3 Events Associated with TLESRs -- 1.11.4 Control of TLESRs -- 1.11.5 Neural Pathway-Mediating TLESRs -- 1.12 Refractory GERD -- 1.12.1 Refractory Gastroesophageal Reflux Disease Without Esophagitis -- Nocturnal Gastric Acid Breakthrough (NAB) -- Non-acid Gastroesophageal Reflux -- Missed Gastroesophageal Reflux Disease -- Functional Heartburn -- Wrong Diagnosis -- 1.12.2 Refractory Gastroesophageal Reflux Disease with Esophagitis -- Pill-Induced Esophagitis -- Autoimmune Skin Diseases -- Acid Hypersecretion -- Eosinophilic Esophagitis -- Genotypic Differences -- 1.12.3 Newer Treatment in Gastroesophageal Reflux Disease -- Extended Release Proton Pump Inhibitors -- Potassium-Competitive Acid Blocker -- TLESR Reducers -- Mucosal Protectant -- 1.13 Achalasia Cardia -- 1.13.1 Normal Esophageal Motor Innervation -- 1.13.2 Pathogenesis of Primary Achalasia -- 1.14 Eosinophilic Esophagitis -- 1.14.1 Endoscopic Findings -- 1.14.2 Histologic Characteristics -- 1.14.3 Treatment Options -- 1.15 Genetic Polymorphism in GERD -- 1.15.1 Introduction -- 1.15.2 Various Types of Polymorphism in Gastroesophageal Reflux Disease.
1.16 Biomarkers for Barrett's Esophagus -- 1.16.1 Diagnosis -- 1.17 Esophageal High-Resolution Manometry: Recent Updates on Chicago Classification 4.0 -- 1.17.1 Procedure -- 1.17.2 Classification of Esophageal Motility Disorders as per Chicago Classification 4.0 (Fig. 1.6) -- 1.18 24-Hour pH Impedance: Lyon Consensus and What Has Changed -- 1.18.1 Indications -- 1.18.2 Testing On or Off Proton Pump Inhibitors -- 1.18.3 Interpretation of pH and pH-Impedance Monitoring -- 1.18.4 Reflux-Symptom Association -- 1.18.5 Novel Metrics -- 1.19 Combined Multichannel Intraluminal Impedance and Esophageal Manometry -- 1.19.1 Indications -- 1.19.2 Principle -- 1.19.3 Patient Protocol -- 1.19.4 Technique -- 1.19.5 Impedance Results Parameters -- 1.19.6 Clinical Application -- 1.20 Third-Space Endoscopy and Its Clinical Utility -- 1.20.1 Third-Space Endoscopy Procedures -- 1.20.2 Principles of Third-Space Endoscopy -- 1.21 Esophageal Stents -- 1.21.1 Indications -- 1.21.2 Types -- 1.21.3 Technique -- 1.21.4 Adverse Events -- Early -- Late -- Chapter 2: Stomach -- 2.1 Embryology -- 2.2 Anatomy and Physiology -- 2.2.1 Gastric Mucosal Anatomy -- Oxyntic or Parietal Glands -- Parietal Cells (Oxyntic Cells) -- Chief Cells -- Endocrine Cells -- D Cells -- Somatostatin -- Enterochromaffin Cells -- Serotonin -- Enterochromaffin-Like Cells or ECL Cells -- Pyloric Glands -- G-Cells -- Gastrin -- Physiology of Gastric Acid Secretion -- Mechanism of Acid Production -- 2.3 Gastric Mucosal Barrier -- 2.3.1 Components of Gastric Barrier -- 2.3.2 Prostaglandins and Their Role in Gastric Mucosal Defense -- 2.4 Gastric Motility -- 2.4.1 ICC -- 2.4.2 Gastric Motility in Response to Solid Meal -- Receptive Relaxation -- Trituration -- Linear Phase of Gastric Emptying -- 2.4.3 Gastric Motility in Response to Liquid Meal -- 2.5 Gastrin -- 2.6 Ghrelin -- 2.6.1 Clinical Relevance. Prader-Willi Syndrome -- Bariatric Surgery -- 2.7 Gastric Microbiota -- 2.7.1 Non-H. pylori Helicobacter Species -- 2.7.2 Clinical Relevance -- Gastric Non-H. Pylori Helicobacter Species -- Enterohepatic Non-H. Pylori Helicobacter Species -- 2.8 Acid Pocket -- 2.8.1 Mechanism -- 2.8.2 Gastroesophageal Reflux Disease and Acid Pocket -- 2.8.3 Management -- 2.9 H. pylori and Pathogenesis of Peptic Ulcer -- 2.9.1 H. pylori -- Transmission -- Bacteriology -- Adaptation of H. pylori to Stomach -- 2.9.2 Pathogenesis of H. pylori-Induced Mucosal Injury -- 2.9.3 Immune-Mediated Injury -- 2.9.4 Host Genetics and H. Pylori Pathogenicity -- 2.9.5 Pathogenesis of Duodenal Ulcer -- 2.10 NSAID and Gastric Mucosal Injury -- 2.11 Pathophysiology of Functional Dyspepsia -- 2.11.1 Pathophysiology of FD -- 2.12 Gastric Cancer Stem Cell -- 2.13 Pathogenesis and Molecular Classification of Gastric Cancer -- 2.13.1 Histologic Subtypes -- 2.13.2 Newer Molecular Classification of Gastric Cancer -- 2.14 H. pylori Treatment Guidelines: The Maastricht V/Florence Consensus Report -- 2.14.1 Indications for Testing for H. pylori -- 2.14.2 Diagnosis -- Tests for Identification of H. pylori -- 2.14.3 Treatment -- First-Line Treatment (Table 2.3) -- First-Line Treatment Failure: Management -- Second-Line Treatment Failure: Management -- Treatment in Patients with Penicillin Allergy -- Tests for Confirmation of H. pylori Eradication -- 2.15 Morphology of Superficial Neoplastic Lesions: Paris Classification -- 2.15.1 Historical Perspective -- 2.15.2 Practical Considerations -- 2.15.3 Endoscopic Staging Based on Morphology -- 2.15.4 Superficial Neoplastic Lesions in Columnar Epithelium Barrett's Esophagus -- 2.15.5 Superficial Neoplastic Lesions in Sub-cardiac Stomach -- 2.15.6 Superficial Neoplastic Lesions in the Colon -- 2.16 Proton Pump Inhibitors: Indications and Side Effects. 2.16.1 Indications -- 2.16.2 Side Effects -- 2.17 Prokinetics: Mechanism and Side Effects (Table 2.8) -- 2.18 Newer Antiplatelets and Anticoagulants: What the GI Physician Needs to Know -- 2.18.1 Risk of GI Bleeding with Newer Antiplatelets -- 2.18.2 Procedures Associated with the Risk of GI Bleed (Table 2.9) -- 2.18.3 Recommended Modification of Antiplatelet or Anticoagulant Use Before the Planned Procedure -- 2.18.4 Strategies for Reversal/Antidote to Newer Anticoagulants During a Life-Threatening Bleed -- Chapter 3: Small Intestine -- 3.1 Development and Malrotation -- 3.1.1 Timeline of Development (Table 3.1) -- 3.1.2 Intestinal Malrotation -- 3.2 Meckel's Diverticulum -- 3.2.1 Surgical Anatomy of Meckel's Diverticulum -- 3.2.2 Types -- Histology -- Clinical Presentation -- Treatment -- 3.3 Enteric Nervous System -- 3.3.1 Functions of Myenteric Plexus -- 3.3.2 Functions of Submucosal Plexus -- 3.4 Villi -- 3.4.1 Function -- 3.5 Microvilli -- 3.5.1 Location -- 3.5.2 Structure -- 3.5.3 Functions -- 3.5.4 Glycocalyx -- 3.5.5 Destruction of Microvilli -- 3.6 Intra-Epithelial Lymphocytes -- 3.6.1 The Upper Limit of the Normal Range of IELs -- 3.6.2 Associated Diseases with Increased IELs -- Increased IELs and Celiac Disease -- Increased IELs and Refractory Sprue -- Increased IELs and Non-celiac Disease-Associated Disorders -- 3.7 Microfold Cells -- 3.7.1 Structure and Function -- 3.7.2 Pathology -- 3.7.3 Development -- 3.8 Paneth Cells -- 3.8.1 Relationship with Stem Cells -- 3.8.2 Sensing Microbiota -- 3.8.3 Secretions -- Defensins -- 3.8.4 Other Secretions -- 3.9 Zona Occludens -- 3.9.1 Physiological Regulation by Na+/Nutrient Cotransport -- 3.9.2 Influence of Cytokines -- Interferon -- Hepatocyte Growth Factor -- Tumour Necrosis Factor -- Other Cytokines -- 3.9.3 Modulation by Leukocytes and Bacteria -- 3.10 Toll-like Receptors. 3.11 Migrating Myoelectric Complexes -- 3.12 Intestinal Pacemaker -- 3.12.1 Interstitial Cells of Cajal -- 3.12.2 Functions -- 3.12.3 Types -- 3.13 Gut Mucosal Barrier and Conditions with Increased Gut Permeability -- 3.13.1 Anatomy of Gut Mucosal Barrier -- 3.13.2 Physiology of Solute Transport Across the Gut Mucosal Barrier and Their Regulation -- Transport via TJ -- 3.13.3 Diseases Associated with Increased Gut Permeability -- 3.14 Small Intestinal Permeability (SIP) and Its Assessment -- 3.14.1 Factors That Determine Permeability -- 3.14.2 Measurement of Small Intestinal Permeability -- 3.14.3 Principles -- 3.14.4 Methods of Measurement -- 3.14.5 Clinical Relevance -- 3.15 Mucosal Defence -- 3.16 Immunoglobulin A -- 3.16.1 Structure (Fig. 3.4) -- 3.16.2 Functions -- 3.16.3 Clinical Significance -- Immunoglobulin A Deficiency -- Immunoglobulin A and Celiac Disease -- 3.17 Defensins -- 3.17.1 Clinical Importance -- 3.18 Enterokinase -- 3.18.1 Application -- 3.18.2 Enterokinase Deficiency -- 3.19 Cholecystokinin -- 3.19.1 Functions -- 3.19.2 Clinical Significance -- 3.20 Secretin -- 3.20.1 Functions -- 3.20.2 Clinical Uses -- 3.21 Incretins -- 3.21.1 Sources -- 3.21.2 Actions -- 3.21.3 Clinical Use -- 3.22 Vitamin B12 Absorption -- 3.22.1 Sources -- 3.22.2 Physiology -- 3.22.3 Diagnosis of Cobalamin Deficiency -- Peripheral Blood Film -- Serum B12 Levels -- 3.22.4 Schilling Test -- Principle -- 3.22.5 Treatment -- 3.23 Iron Absorption and Metabolism -- 3.23.1 Iron Absorption and Transport -- 3.23.2 Iron Transport Across the Apical Membrane of Enterocytes -- 3.23.3 Iron Transport Across the Basolateral Membrane of Enterocytes -- 3.23.4 Regulation of Iron Stores -- 3.24 Copper Metabolism -- 3.24.1 Absorption of Copper -- 3.24.2 Copper Transport -- 3.24.3 Role of Copper -- 3.24.4 Copper Deficiency: Causes and Diagnosis -- 3.24.5 Copper Toxicity. 3.24.6 Disease Associated with Copper Metabolism. |
| Record Nr. | UNINA-9910861085603321 |
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Choudhuri Gourdas
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| Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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