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Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma
Analysis File of Drug-Induced Lung Injury : Expert Opinion for Analysis of Big Data / / by Akihiko Gemma
Autore Gemma Akihiko
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (122 pages)
Disciplina 616.2
Soggetto topico Respiratory organs - Diseases
Medical genetics
Diseases - Causes and theories of causation
Oncology
Pharmacology
Genetics - Research
Pneumology
Clinical Genetics
Pathogenesis
Genetics Research
ISBN 9789819734467
9789819734450
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Part I Understanding Drug-Induced Lung Injuries -- 1 Understanding Drug-Induced Lung Injuries -- Part 2 Actual Practice in Drug-Induced Lung Injuries of Each Drug -- 2 EGFR inhibitors (gefitinib, erlotinib, afatinib, osimertinib) -- 3 Anti-EGFR antibodies (cetuximab, panitumumab, necitumumab) -- 4 mTOR inhibitors (temsirolimus, everolimus) -- 5 Proteasome inhibitor (bortezomib) -- 6 Immune checkpoint inhibitors (nivolumab, pembrolizumab, atezolizumab, durvalumab) -- 7 Neoangiogenesis inhibitors (sunitinib, sorafenib, bevacizumab) -- 8 Other molecular targeted drugs (crizotinib, alectinib, etc.) -- 9 Antibody-drug conjugates (ADC) (trastuzumab emtansine, trastuzumab deruxtecan) -- 10 Anti-cancer drugs (TS-1, taxanes, CPT-11, platinum-containing drugs, etc.).
Record Nr. UNINA-9910878983003321
Gemma Akihiko  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag
Andrology : Male Reproductive Health and Dysfunction / / edited by Eberhard Nieschlag, Hermann M. Behre, Sabine Kliesch, Susan Nieschlag
Autore Nieschlag Eberhard
Edizione [4th ed. 2023.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (840 pages)
Disciplina 616.6/5
616.65
Altri autori (Persone) BehreHermann M
KlieschSabine
NieschlagSusan
Soggetto topico Reproductive health
Urology
Endocrinology
Dermatology
Medical genetics
Reproductive Medicine
Clinical Genetics
ISBN 3-031-31574-X
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto 1. Scope and Goals of Andrology -- Part I. Physiologic Basis -- 2. Physiology of testicular function -- 3. Physiology of sperm maturation and fertilization -- Part II. Classification and Diagnosis of Andrological Disorders -- 4. Classification of andrological disorders -- 5. Anamnesis and Physical Examination -- 6. Ultrasound imaging in andrology -- 7. Endocrine Laboratory Diagnosis -- 8. Cytogenetic and molecular genetic diagnostics -- 9. Semen analysis -- 10. Sperm quality and sperm function tests -- 11. Biopsy and histology of the testis -- Part III. Clinics in Andrology: Secondary Hypogonadism -- 12. Congenital hypogonadotropic hypogonadism of hypothalamic origin -- 13. Congenital hypogonadotropic hypogonadism of pituitary origin and rare syndromes with central hypogonadism -- 14. Delayed puberty in boys -- 15. Pituitary hypogonadism, hyperprolactinemia, and gonadotropin-producing tumors -- Part IV. Clinics in Andrology: Primary Hypogonadism (Disorders at the Testicular Level) -- 16. Anorchia and Polyorchidism -- 17. Undescended testes -- 18. Varicocele -- 19. Orchitis -- 20. Disorders of spermatogenesis and spermiogenesis -- 21. Klinefelter syndrome -- 22. XX male and XYY karyotype -- 23 Structural chromosomal changes -- 24. Testicular tumors -- 25. Senescence and late-onset hypogonadism -- Part V. Clinics in Andrology: Diseases of Seminal Ducts and Accessory Sex Organs -- 26. Infections and inflammation of the seminal ducts and accessory sex glands -- 27. Obstructions of the seminal ducts, cystic fibrosis and congenital aplasia of the ductus deferens -- 28. Immunologically induced infertility -- 29. Andrologically relevant changes in the external genitals -- 30. Disorders of erection, cohabitation and ejaculation -- Part VI. Clinics in Andrology: Disorders of Sexual Differentiation and Androgen Target Organs -- 31. Variants of sex development -- 32. Gynecomastia -- 33. Male androgenetic alopecia -- Part VII. Clinics in Andrology: Disorders of Reproductive Health caused by Environmental and Systemic Diseases -- 34. Testicular dysfunction in systemic diseases -- 35. Environmental Influences on Male Reproductive Health -- Part VIII. Andrological Therapy -- 36. Therapy with testosterone -- 37. Abuse of anabolic androgenic steroids (AAS) for doping -- 38. Treatment of hypogonadism of hypothalamic or pituitary origin -- 39. Therapeutic attempts in idiopathic infertility -- 40. Gynecology relevant to andrology -- 41. Assisted fertilization -- 42. Cryopreservation of human sperm and testicular germ cell tissue for fertility reserve -- Part IX. Sexual Health -- 43. Sexual Medicine and Andrology -- 44. Involuntary Childlessness from the Perspective of Sexual Medicine -- Part X. Male Contraception -- 45. Male contribution to contraception -- 46. Vasectomy -- 47. Approaches to hormonal male contraception -- 48. Non-hormonal Approaches to Male Contraception -- Part XI. Law and Ethics in Reproductive Medicine -- 49. Legal regulations in Andrology and Reproductive Medicine -- 50. Ethical criteria of reproductive medicine. .
Record Nr. UNINA-9910755083003321
Nieschlag Eberhard  
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023
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Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville
Bacteriophages : Biology, Technology, Therapy / / edited by David R. Harper, Stephen T. Abedon, Benjamin H. Burrowes, Malcolm L. McConville
Edizione [1st ed. 2021.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
Descrizione fisica 1 online resource (173 illus., 102 illus. in color. eReference.)
Disciplina 579.26
Soggetto topico Medical genetics
Bacteria
Medicine - Research
Biology - Research
Clinical Genetics
Biomedical Research
ISBN 3-319-41986-2
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Bacteriophage Biology -- History of Bacteriophages -- Bacteriophage Technology -- Agriculture, Food and Environmental Use of Bacteriophages -- Therapeutic Use of Bacteriophages.
Record Nr. UNINA-9910483262703321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2021
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Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen
Cell Biology and Translational Medicine, Volume 5 : Stem Cells: Translational Science to Therapy / / edited by Kursad Turksen
Edizione [1st ed. 2019.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
Descrizione fisica 1 online resource (179 pages)
Disciplina 616.02774
Collana Cell Biology and Translational Medicine
Soggetto topico Stem cells
Regenerative medicine
Medical genetics
Biotechnology
Stem Cell Biology
Regenerative Medicine and Tissue Engineering
Clinical Genetics
Chemical Bioengineering
ISBN 3-030-17589-8
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Therapeutic Cardiac Patches for Repairing the Myocardium -- Human Induced Pluripotent Stem Cells in the Curative Treatment of Diabetes and Potential Impediments Ahead -- CRISPR/Cas9 for Sickle Cell Disease: Applications, Future possibilities, and Challenges -- Photoresponsive Hydrogels with Photoswitchable Stiffness: Emerging Platforms to Study Temporal Aspects of Mesenchymal Stem Cell Responses to Extracellular Stiffness Regulation -- Cellular complexity at the interface: Challenges in enthesis tissue engineering -- Induced Pluripotent Stem Cells in Disease Modelling and Regeneration -- Stem cells for the oromaxillofacial area: Could they be a promising source for regeneration in dentistry? -- Stem Cells Derived from Dental Tissues -- A Novel Virtue in Stem Cell Research: Exosomes and Their Role in Differentiation -- Mesenchymal Stem Cells as Regulators of Carcinogenesis.
Record Nr. UNINA-9910337943603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019
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Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan
Children with Differences in Sex Development : Taking a Multidisciplinary Management Approach / / edited by Simmi K. Ratan
Autore Ratan Simmi K
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (763 pages)
Disciplina 618.928583
Soggetto topico Pediatrics
Children - Surgery
Hormones
Medical genetics
Chromosomes
Pediatric Surgery
Hormone
Clinical Genetics
ISBN 9789819716395
9789819716388
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Anatomical differentiation and development of gonads -- Molecular regulation of sexual differentiation -- Hormonal regulation during gonadal development -- rain imprinting during gonadal differentiation -- Gender identity and role -- Gender dysphoria in DSD children -- Metaanalysis and current literature on gender identity disorders -- Psychopathological and psychiatric co-morbidities ingender dysphoria -- Legal aspects of DSD Indian & International scenario -- E volution and history of landmark judgements for DSD -- Terminology and clinical evaluation in the Diagnosis of DSD -- Cytogenetic and Molecular Genetic investigations in DSD -- Imaging and Endoscopy in the Diagnosis of DSD -- Endocrine profiling in diagnosis -- Pathology of DSD.
Record Nr. UNINA-9910906193303321
Ratan Simmi K  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman
Clinical Metabolomics Applications in Genetic Diseases / / edited by Anas M. Abdel Rahman
Autore Abdel Rahman Anas M
Edizione [1st ed. 2023.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
Descrizione fisica 1 online resource (349 pages)
Disciplina 616.042
Soggetto topico Medical genetics
Metabolism - Disorders
Biochemistry
Metabolism
Cytology
Medicine
Bioinformatics
Clinical Genetics
Metabolic Disease
Metabolic Pathways
Clinical Medicine
ISBN 981-9951-62-3
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Chapter 1. The advanced technology and clinical application in metabolomics -- Chapter 2. Mass Spectrometry-Based Metabolomics for the Clinical Laboratory -- Chapter 3. Metabolomics: a pipeline for biomarker discovery in genetic diseases -- Chapter 4. Bioinformatics Tools for Clinical Metabolomics -- Chapter 5. Untargeted Metabolomics in Newborn Screening -- Chapter 6. Untargeted Metabolomics, Targeted Care: The Clinical Utilities of Bedside Metabolomics -- Chapter 7. Metabolomics in the Study of Human Mitochondrial Diseases -- Chapter 8. Metabolomics of Rare endocrine, genetic disease- A focus on the Pituitary gland -- Chapter 9. Metabolomics and genetics of rare endocrine disease - adrenal, parathyroid glands, and cystic fibrosis -- Chapter 10. Metabolomics role in personalized medicine: An update -- Chapter 11. Lipidomic Profiling in Clinical Practice Using LC-MS -- Chapter 12. Bringing Human Serum Lipidomics to the Forefront of Clinical Practice: Two Clinical Diagnosis Success Stories -- Chapter 13. LC-MS based population metabolomics: a mini-review of recent studies and challenges from sample collection to data processing -- Chapter 14. Metabolomics and transcriptomics approach to understand the pathophysiology of interstitial lung disease -- Chapter 15. Transferring metabolomics to portable diagnostic devices- Trending in biosensors.
Record Nr. UNINA-9910746962103321
Abdel Rahman Anas M  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023
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DNA Know Thyself : Living in a DNA World / / by Ray J Rose
DNA Know Thyself : Living in a DNA World / / by Ray J Rose
Autore Rose Ray J
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (185 pages)
Disciplina 616.042
Soggetto topico Medical genetics
Molecular genetics
Developmental genetics
Biotechnology
Genetics
Medical Genetics
Clinical Genetics
Molecular Genetics
Developmental Genetics
Genetics and Genomics
ISBN 9789819783816
9789819783809
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Introduction -- Genesis of DNA and cells like ours -- DNA and the diversity of life sustains us and our environment -- The evolving story of DNA, genes and genomes -- We come from single cells – from gene regulation to stem cells -- The cell division cycle and the biology of cancer -- Generation upon generation -- DNA and ageing -- RNA and DNA viruses reproduce in cells -- DNA and the rise of modern biotechnology -- DNA and food and nutrition for 10 billion people -- DNA and the environment -- Gene therapy for human disease -- Synthetic biology – a new frontier -- We have the whole world in our hands.
Record Nr. UNINA-9910908371703321
Rose Ray J  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases [[electronic resource] /] / edited by Christopher L. Cioffi
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Descrizione fisica 1 online resource (IX, 272 p. 1 illus.)
Disciplina 615.19
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Ophthalmology
Pharmaceutical chemistry
Medical genetics
Medicinal Chemistry
Pharmaceutics
Clinical Genetics
ISBN 3-030-56619-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. .
Record Nr. UNINA-9910420948603321
Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020
Materiale a stampa
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Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi
Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases / / edited by Christopher L. Cioffi
Edizione [1st ed. 2020.]
Pubbl/distr/stampa Springer International Publishing, 2020
Descrizione fisica 1 online resource (IX, 272 p. 1 illus.)
Disciplina 615.19
Collana Topics in Medicinal Chemistry
Soggetto topico Medicinal chemistry
Ophthalmology
Pharmaceutical chemistry
Medical genetics
Medicinal Chemistry
Pharmaceutics
Clinical Genetics
ISBN 3-030-56619-6
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto An Overview of Retinal Diseases and Current Ocular Drug Discovery -- Ocular Pharmacokinetics and Drug Delivery Challenges -- Models of Pathologies Associated with Age-related Macular Degeneration and Their Utilities in Drug Discovery -- Recent Developments in Agents for the Treatment of Age-Related Macular Degeneration and Stargardt Disease -- Targets and Strategies toward the Development of Therapeutics for Diabetic Retinopathy and Diabetic Macular Edema -- Recent Developments for the Treatment of Glaucoma -- Emerging Gene Therapy Treatments for Retinal Degenerative Diseases. .
Record Nr. UNINA-9910863166203321
Springer International Publishing, 2020
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Gastroenterology and Hepatology : Bench to Bedside / / edited by Gourdas Choudhuri, Anil C Anand, P Piramanayagam
Gastroenterology and Hepatology : Bench to Bedside / / edited by Gourdas Choudhuri, Anil C Anand, P Piramanayagam
Autore Choudhuri Gourdas
Edizione [1st ed. 2024.]
Pubbl/distr/stampa Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
Descrizione fisica 1 online resource (0 pages)
Disciplina 616.33
Altri autori (Persone) AnandAnil C
PiramanayagamP
Soggetto topico Diagnosis
Internal medicine
Gastrointestinal system
Medical genetics
Internal Medicine
Gastrointestinal System
Clinical Genetics
ISBN 981-9992-87-7
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Intro -- Foreword -- Acknowledgments -- Introduction -- Contents -- Chapter 1: Esophagus -- 1.1 Lower Esophageal Sphincter -- 1.1.1 Anatomy -- 1.1.2 Embryology -- 1.1.3 Physiology -- 1.2 Wall Layer of the Esophagus -- 1.3 Esophageal Constrictions -- 1.4 Blood Supply of the Esophagus -- 1.5 Portosystemic Anastomosis -- 1.6 Lymphatic Drainage of Esophagus -- 1.7 Esophageal Rings -- 1.7.1 A Ring -- 1.7.2 B Ring -- 1.7.3 Corrugated Ringed Esophagus -- 1.8 Esophageal Webs -- 1.9 Esophagus in Portal Hypertension -- 1.9.1 Changes in Portal Hypertension -- 1.10 Tracheo-Esophageal Fistula -- 1.10.1 Diagnosis -- 1.10.2 Treatment -- 1.11 Transient Lower Esophageal Sphincter Relaxation -- 1.11.1 Definition -- 1.11.2 Physiology -- 1.11.3 Events Associated with TLESRs -- 1.11.4 Control of TLESRs -- 1.11.5 Neural Pathway-Mediating TLESRs -- 1.12 Refractory GERD -- 1.12.1 Refractory Gastroesophageal Reflux Disease Without Esophagitis -- Nocturnal Gastric Acid Breakthrough (NAB) -- Non-acid Gastroesophageal Reflux -- Missed Gastroesophageal Reflux Disease -- Functional Heartburn -- Wrong Diagnosis -- 1.12.2 Refractory Gastroesophageal Reflux Disease with Esophagitis -- Pill-Induced Esophagitis -- Autoimmune Skin Diseases -- Acid Hypersecretion -- Eosinophilic Esophagitis -- Genotypic Differences -- 1.12.3 Newer Treatment in Gastroesophageal Reflux Disease -- Extended Release Proton Pump Inhibitors -- Potassium-Competitive Acid Blocker -- TLESR Reducers -- Mucosal Protectant -- 1.13 Achalasia Cardia -- 1.13.1 Normal Esophageal Motor Innervation -- 1.13.2 Pathogenesis of Primary Achalasia -- 1.14 Eosinophilic Esophagitis -- 1.14.1 Endoscopic Findings -- 1.14.2 Histologic Characteristics -- 1.14.3 Treatment Options -- 1.15 Genetic Polymorphism in GERD -- 1.15.1 Introduction -- 1.15.2 Various Types of Polymorphism in Gastroesophageal Reflux Disease.
1.16 Biomarkers for Barrett's Esophagus -- 1.16.1 Diagnosis -- 1.17 Esophageal High-Resolution Manometry: Recent Updates on Chicago Classification 4.0 -- 1.17.1 Procedure -- 1.17.2 Classification of Esophageal Motility Disorders as per Chicago Classification 4.0 (Fig. 1.6) -- 1.18 24-Hour pH Impedance: Lyon Consensus and What Has Changed -- 1.18.1 Indications -- 1.18.2 Testing On or Off Proton Pump Inhibitors -- 1.18.3 Interpretation of pH and pH-Impedance Monitoring -- 1.18.4 Reflux-Symptom Association -- 1.18.5 Novel Metrics -- 1.19 Combined Multichannel Intraluminal Impedance and Esophageal Manometry -- 1.19.1 Indications -- 1.19.2 Principle -- 1.19.3 Patient Protocol -- 1.19.4 Technique -- 1.19.5 Impedance Results Parameters -- 1.19.6 Clinical Application -- 1.20 Third-Space Endoscopy and Its Clinical Utility -- 1.20.1 Third-Space Endoscopy Procedures -- 1.20.2 Principles of Third-Space Endoscopy -- 1.21 Esophageal Stents -- 1.21.1 Indications -- 1.21.2 Types -- 1.21.3 Technique -- 1.21.4 Adverse Events -- Early -- Late -- Chapter 2: Stomach -- 2.1 Embryology -- 2.2 Anatomy and Physiology -- 2.2.1 Gastric Mucosal Anatomy -- Oxyntic or Parietal Glands -- Parietal Cells (Oxyntic Cells) -- Chief Cells -- Endocrine Cells -- D Cells -- Somatostatin -- Enterochromaffin Cells -- Serotonin -- Enterochromaffin-Like Cells or ECL Cells -- Pyloric Glands -- G-Cells -- Gastrin -- Physiology of Gastric Acid Secretion -- Mechanism of Acid Production -- 2.3 Gastric Mucosal Barrier -- 2.3.1 Components of Gastric Barrier -- 2.3.2 Prostaglandins and Their Role in Gastric Mucosal Defense -- 2.4 Gastric Motility -- 2.4.1 ICC -- 2.4.2 Gastric Motility in Response to Solid Meal -- Receptive Relaxation -- Trituration -- Linear Phase of Gastric Emptying -- 2.4.3 Gastric Motility in Response to Liquid Meal -- 2.5 Gastrin -- 2.6 Ghrelin -- 2.6.1 Clinical Relevance.
Prader-Willi Syndrome -- Bariatric Surgery -- 2.7 Gastric Microbiota -- 2.7.1 Non-H. pylori Helicobacter Species -- 2.7.2 Clinical Relevance -- Gastric Non-H. Pylori Helicobacter Species -- Enterohepatic Non-H. Pylori Helicobacter Species -- 2.8 Acid Pocket -- 2.8.1 Mechanism -- 2.8.2 Gastroesophageal Reflux Disease and Acid Pocket -- 2.8.3 Management -- 2.9 H. pylori and Pathogenesis of Peptic Ulcer -- 2.9.1 H. pylori -- Transmission -- Bacteriology -- Adaptation of H. pylori to Stomach -- 2.9.2 Pathogenesis of H. pylori-Induced Mucosal Injury -- 2.9.3 Immune-Mediated Injury -- 2.9.4 Host Genetics and H. Pylori Pathogenicity -- 2.9.5 Pathogenesis of Duodenal Ulcer -- 2.10 NSAID and Gastric Mucosal Injury -- 2.11 Pathophysiology of Functional Dyspepsia -- 2.11.1 Pathophysiology of FD -- 2.12 Gastric Cancer Stem Cell -- 2.13 Pathogenesis and Molecular Classification of Gastric Cancer -- 2.13.1 Histologic Subtypes -- 2.13.2 Newer Molecular Classification of Gastric Cancer -- 2.14 H. pylori Treatment Guidelines: The Maastricht V/Florence Consensus Report -- 2.14.1 Indications for Testing for H. pylori -- 2.14.2 Diagnosis -- Tests for Identification of H. pylori -- 2.14.3 Treatment -- First-Line Treatment (Table 2.3) -- First-Line Treatment Failure: Management -- Second-Line Treatment Failure: Management -- Treatment in Patients with Penicillin Allergy -- Tests for Confirmation of H. pylori Eradication -- 2.15 Morphology of Superficial Neoplastic Lesions: Paris Classification -- 2.15.1 Historical Perspective -- 2.15.2 Practical Considerations -- 2.15.3 Endoscopic Staging Based on Morphology -- 2.15.4 Superficial Neoplastic Lesions in Columnar Epithelium Barrett's Esophagus -- 2.15.5 Superficial Neoplastic Lesions in Sub-cardiac Stomach -- 2.15.6 Superficial Neoplastic Lesions in the Colon -- 2.16 Proton Pump Inhibitors: Indications and Side Effects.
2.16.1 Indications -- 2.16.2 Side Effects -- 2.17 Prokinetics: Mechanism and Side Effects (Table 2.8) -- 2.18 Newer Antiplatelets and Anticoagulants: What the GI Physician Needs to Know -- 2.18.1 Risk of GI Bleeding with Newer Antiplatelets -- 2.18.2 Procedures Associated with the Risk of GI Bleed (Table 2.9) -- 2.18.3 Recommended Modification of Antiplatelet or Anticoagulant Use Before the Planned Procedure -- 2.18.4 Strategies for Reversal/Antidote to Newer Anticoagulants During a Life-Threatening Bleed -- Chapter 3: Small Intestine -- 3.1 Development and Malrotation -- 3.1.1 Timeline of Development (Table 3.1) -- 3.1.2 Intestinal Malrotation -- 3.2 Meckel's Diverticulum -- 3.2.1 Surgical Anatomy of Meckel's Diverticulum -- 3.2.2 Types -- Histology -- Clinical Presentation -- Treatment -- 3.3 Enteric Nervous System -- 3.3.1 Functions of Myenteric Plexus -- 3.3.2 Functions of Submucosal Plexus -- 3.4 Villi -- 3.4.1 Function -- 3.5 Microvilli -- 3.5.1 Location -- 3.5.2 Structure -- 3.5.3 Functions -- 3.5.4 Glycocalyx -- 3.5.5 Destruction of Microvilli -- 3.6 Intra-Epithelial Lymphocytes -- 3.6.1 The Upper Limit of the Normal Range of IELs -- 3.6.2 Associated Diseases with Increased IELs -- Increased IELs and Celiac Disease -- Increased IELs and Refractory Sprue -- Increased IELs and Non-celiac Disease-Associated Disorders -- 3.7 Microfold Cells -- 3.7.1 Structure and Function -- 3.7.2 Pathology -- 3.7.3 Development -- 3.8 Paneth Cells -- 3.8.1 Relationship with Stem Cells -- 3.8.2 Sensing Microbiota -- 3.8.3 Secretions -- Defensins -- 3.8.4 Other Secretions -- 3.9 Zona Occludens -- 3.9.1 Physiological Regulation by Na+/Nutrient Cotransport -- 3.9.2 Influence of Cytokines -- Interferon -- Hepatocyte Growth Factor -- Tumour Necrosis Factor -- Other Cytokines -- 3.9.3 Modulation by Leukocytes and Bacteria -- 3.10 Toll-like Receptors.
3.11 Migrating Myoelectric Complexes -- 3.12 Intestinal Pacemaker -- 3.12.1 Interstitial Cells of Cajal -- 3.12.2 Functions -- 3.12.3 Types -- 3.13 Gut Mucosal Barrier and Conditions with Increased Gut Permeability -- 3.13.1 Anatomy of Gut Mucosal Barrier -- 3.13.2 Physiology of Solute Transport Across the Gut Mucosal Barrier and Their Regulation -- Transport via TJ -- 3.13.3 Diseases Associated with Increased Gut Permeability -- 3.14 Small Intestinal Permeability (SIP) and Its Assessment -- 3.14.1 Factors That Determine Permeability -- 3.14.2 Measurement of Small Intestinal Permeability -- 3.14.3 Principles -- 3.14.4 Methods of Measurement -- 3.14.5 Clinical Relevance -- 3.15 Mucosal Defence -- 3.16 Immunoglobulin A -- 3.16.1 Structure (Fig. 3.4) -- 3.16.2 Functions -- 3.16.3 Clinical Significance -- Immunoglobulin A Deficiency -- Immunoglobulin A and Celiac Disease -- 3.17 Defensins -- 3.17.1 Clinical Importance -- 3.18 Enterokinase -- 3.18.1 Application -- 3.18.2 Enterokinase Deficiency -- 3.19 Cholecystokinin -- 3.19.1 Functions -- 3.19.2 Clinical Significance -- 3.20 Secretin -- 3.20.1 Functions -- 3.20.2 Clinical Uses -- 3.21 Incretins -- 3.21.1 Sources -- 3.21.2 Actions -- 3.21.3 Clinical Use -- 3.22 Vitamin B12 Absorption -- 3.22.1 Sources -- 3.22.2 Physiology -- 3.22.3 Diagnosis of Cobalamin Deficiency -- Peripheral Blood Film -- Serum B12 Levels -- 3.22.4 Schilling Test -- Principle -- 3.22.5 Treatment -- 3.23 Iron Absorption and Metabolism -- 3.23.1 Iron Absorption and Transport -- 3.23.2 Iron Transport Across the Apical Membrane of Enterocytes -- 3.23.3 Iron Transport Across the Basolateral Membrane of Enterocytes -- 3.23.4 Regulation of Iron Stores -- 3.24 Copper Metabolism -- 3.24.1 Absorption of Copper -- 3.24.2 Copper Transport -- 3.24.3 Role of Copper -- 3.24.4 Copper Deficiency: Causes and Diagnosis -- 3.24.5 Copper Toxicity.
3.24.6 Disease Associated with Copper Metabolism.
Record Nr. UNINA-9910861085603321
Choudhuri Gourdas  
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024
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