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Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng
| Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng |
| Pubbl/distr/stampa | Hoboken, N.J. : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (x, 456 pages) : illustrations |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
LinGuo-Qiang <1943->
YouQi-Dong ChengJie-Fei |
| Soggetto topico |
Chiral drugs
Drug development Structure-activity relationships (Biochemistry) |
| ISBN |
1-283-23983-3
9786613239839 1-118-07563-3 1-118-07564-1 1-118-07562-5 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: Chapter 1. Overview of chirality and chiral drugs (Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng). -- Chapter 2. Chiral drugs through asymmetric synthesis (Guo-Quiang Lin and Xing-Wen Sun). -- Chapter 3. Chiral drugs via biocatalytical approaches (Jianqiang Wang and Wenya Lu). -- Chapter 4. Chiral resolution (Qi-Dong You). -- Chapter 5. Fluorine-containing chiral drugs (Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing). -- Chapter 6. Industrial application of chiral technologies (Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni). -- Chapter 7. Computation modeling study on mechanism-of-action of chiral drugs (Deping Wang and Eric Gu). -- Chapter 8. Pharmacology of chiral drugs (Yongge Liu and Xiao-Hui Gu). -- Chapter 9. Pharmacokinetics of chiral drugs (Hanqing Dong, Xiaochuan Guo and Zengbiao Li). -- Chapter 10. Toxicology of chiral drugs (Guang Yang and Hai-Zhi Bu). -- Chapter 11. Representative chiral drugs (Jiangqin Sun, Dingguo Liu and Zhimin Wang). |
| Record Nr. | UNINA-9910139598603321 |
| Hoboken, N.J. : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng
| Chiral drugs : chemistry and biological action / / edited by Guo-Qiang Lin, Qi-Dong You, Jie-Fei Cheng |
| Pubbl/distr/stampa | Hoboken, N.J. : , : Wiley, , 2011 |
| Descrizione fisica | 1 online resource (x, 456 pages) : illustrations |
| Disciplina | 615/.19 |
| Altri autori (Persone) |
LinGuo-Qiang <1943->
YouQi-Dong ChengJie-Fei |
| Soggetto topico |
Chiral drugs
Drug development Structure-activity relationships (Biochemistry) |
| ISBN |
1-283-23983-3
9786613239839 1-118-07563-3 1-118-07564-1 1-118-07562-5 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Machine generated contents note: Chapter 1. Overview of chirality and chiral drugs (Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng). -- Chapter 2. Chiral drugs through asymmetric synthesis (Guo-Quiang Lin and Xing-Wen Sun). -- Chapter 3. Chiral drugs via biocatalytical approaches (Jianqiang Wang and Wenya Lu). -- Chapter 4. Chiral resolution (Qi-Dong You). -- Chapter 5. Fluorine-containing chiral drugs (Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing). -- Chapter 6. Industrial application of chiral technologies (Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni). -- Chapter 7. Computation modeling study on mechanism-of-action of chiral drugs (Deping Wang and Eric Gu). -- Chapter 8. Pharmacology of chiral drugs (Yongge Liu and Xiao-Hui Gu). -- Chapter 9. Pharmacokinetics of chiral drugs (Hanqing Dong, Xiaochuan Guo and Zengbiao Li). -- Chapter 10. Toxicology of chiral drugs (Guang Yang and Hai-Zhi Bu). -- Chapter 11. Representative chiral drugs (Jiangqin Sun, Dingguo Liu and Zhimin Wang). |
| Record Nr. | UNINA-9910816761103321 |
| Hoboken, N.J. : , : Wiley, , 2011 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner
| Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
| Soggetto genere / forma | Electronic books. |
| Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
| ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
| Record Nr. | UNINA-9910144273203321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner
| Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
| Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
| ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
| Record Nr. | UNINA-9910830465203321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner
| Chirality in drug research [[electronic resource] /] / edited by Eric Francotte and Wolfgang Lindner |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, c2006 |
| Descrizione fisica | 1 online resource (373 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
FrancotteEric
LindnerW (Wolfgang) |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Chiral drugs
Drugs - Research Drug development Médicaments - Recherche Médicaments - Développement |
| Soggetto non controllato | legemidler - forskning - legemiddelutvikling - legemiddelanalyse - farmasøytisk kjemi - medikamenter - medisiner - legemiddelkjemi - syntese |
| ISBN |
1-281-08787-4
9786611087876 3-527-60943-1 3-527-60871-0 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Chiral drugs from a historical point of view / Joseph Gal -- Stereoselective synthesis of drugs : an industrial perspective / Hans-Jürgen Federsel -- Aspects of chirality in natural products drug discovery / Philipp Krastel, Frank Petersen, Silvio Roggo, Esther Schmitt, Ansgar Schuffenhauer -- Biotransformation methods for preparing chiral drugs and drug intermediates / Michael Müller, Marcel Wubbolts -- Resolution of chiral drugs and drug intermediates by crystallisation / Kazuhiko Saigo and Kenichi Sakai -- Isolation and production of optically pure drugs by enantioselective chromatography / Eric Francotte -- Stereoselective chromatographic methods for drug analysis / Norbert M. Maier, Wolfgang Lindner -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis / Serge Rudaz, Jean-Luc Veuthey -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or p1 sH NMR anisotropy methods / Nobuyuki Harada -- Keywords in chirality modeling : molecular modeling of chirality : software and literature research on chirality in modeling, chirality in docking, chiral ligand-receptor interaction and symmetry / Gerd Folkers, Mine Yarim, Pavel Pospisil. |
| Record Nr. | UNINA-9910840775703321 |
| Weinheim, : Wiley-VCH, c2006 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker
| Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker |
| Autore | Walker Debora Tanja |
| Edizione | [1. Auflage.] |
| Pubbl/distr/stampa | Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 |
| Descrizione fisica | 1 online resource (124 pages) : illustrations (some color) |
| Disciplina | 615.19 |
| Soggetto topico | Chiral drugs |
| Soggetto genere / forma | Electronic books. |
| ISBN | 3-7369-8050-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910511397203321 |
Walker Debora Tanja
|
||
| Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker
| Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker |
| Autore | Walker Debora Tanja |
| Edizione | [1. Auflage.] |
| Pubbl/distr/stampa | Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 |
| Descrizione fisica | 1 online resource (124 pages) : illustrations (some color) |
| Disciplina | 615.19 |
| Soggetto topico | Chiral drugs |
| ISBN | 3-7369-8050-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910794712003321 |
|
Walker Debora Tanja
|
||
| Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker
| Magnetically actuated micro- and nanopropellers / / vorgelegt von Debora Tanja Walker |
| Autore | Walker Debora Tanja |
| Edizione | [1. Auflage.] |
| Pubbl/distr/stampa | Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 |
| Descrizione fisica | 1 online resource (124 pages) : illustrations (some color) |
| Disciplina | 615.19 |
| Soggetto topico | Chiral drugs |
| ISBN | 3-7369-8050-7 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910814283103321 |
|
Walker Debora Tanja
|
||
| Gottingen, [Germany] : , : Cuvillier Verlag, , 2015 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular biology in medicinal chemistry [[electronic resource] /] / edited by Th. Dingermann, D. Steinhilber and G. Folkers
| Molecular biology in medicinal chemistry [[electronic resource] /] / edited by Th. Dingermann, D. Steinhilber and G. Folkers |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2004 |
| Descrizione fisica | 1 online resource (437 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
DingermannTheodor
FolkersGerd SteinhilberDieter <1959-> |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Chiral drugs
Genomics Molecular biology Molecular pharmacology Pharmacogenomics |
| Soggetto genere / forma | Electronic books. |
| ISBN |
1-280-52027-2
9786610520275 3-527-60518-5 3-527-60266-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Molecular Biology in Medicinal Chemistry; Contents; Preface; Foreword; Contributors; Part I Molecular Targets; 1 Cellular Assays in Drug Discovery; 1.1 Introduction; 1.1.1 Positioning Cellular Assays; 1.1.2 Impact on Drug Discovery; 1.1.3 Classification of Cellular Assays; 1.1.4 Progress in Tools and Technologies for Cellular Compound Profiling; 1.2 Membrane Proteins and Fast Cellular Responses; 1.2.1 Receptors; 1.2.1.1 FLIPR Technology for Detection of Intracellular Calcium Release; 1.2.1.2 Competitive Immunoassay for Detection of Intracellular cAMP
1.2.1.3 Enzyme Fragment Complementation (EFC) Technology1.2.2 Membrane Transport Proteins; 1.2.2.1 Ion Channels; 1.2.2.2 MDR Proteins; 1.3 Gene and Protein Expression Profiling in High-throughput Formats; 1.3.1 Reporter Gene Assays in Lead Finding; 1.3.2 Reporter Gene Assays in Lead Optimization; 1.4 Spatio-temporal Assays and Subpopulation Analysis; 1.4.1 Phosphorylation Stage-specific Antibodies; 1.4.2 Target-protein-specific Antibodies; 1.4.3 Protein-GFP Fusions; 1.4.4 Fluorescence Resonance Energy Transfer (FRET) 1.4.5 GPCR Activation using Bioluminescence Resonance Energy Transfer (BRET)1.4.6 Protein Fragment Complementation Assays (PCA); 1.5 Phenotypic Assays; 1.5.1 Proliferation/Respiration/Toxicity; 1.5.2 Apoptosis; 1.5.3 Differentiation; 1.5.4 Monitoring Cell Metabolism; 1.5.5 Other Phenotypic Assays; Acknowledgments; References; 2 Gene Knockout Models; 2.1 Introduction; 2.2 Gene Knockout Mice; 2.2.1 ES Cells; 2.2.2 Targeting Vector; 2.2.3 Selection of Recombinant ES Cells; 2.2.4 Injection of Recombinant ES Cells into Blastocysts and Blastocyst Transfer to Pseudopregnant Recipients 2.2.5 Chimeras and F1 and F2 Offspring2.3 Tissue-Specific Gene Expression; 2.3.1 Ligand-Activated CRE Recombinases; 2.3.2 The Tetracycline/Doxycycline-Inducible Expression System; 2.4 Transgenic Mice; 2.5 Targeted Gene Disruption in Drosophila; 2.6 Targeted Gene Knockdown in Zebrafish; 2.7 Targeted Caenorhabditis Elegans Deletion Strains; References; 3 Reporter Gene Assay Systems for the Investigation of G-protein-coupled Receptors; 3.1 Receptors and Cellular Communication; 3.1.1 Ion Channel-linked Receptors; 3.1.2 Enzyme-linked Cell-surface Receptors; 3.1.3 GPCRs 3.2 Affinity and Activity of GPCR Ligands3.3 The Role of Transcription Factors in Gene Expression; 3.3.1 CREB; 3.3.2 SRF; 3.3.3 STAT Proteins; 3.3.4 c-Jun; 3.3.5 NF-AT; 3.4 Reporter Genes; 3.4.1 CAT; 3.4.2 β-Gal; 3.4.3 β-Glucuronidase; 3.4.4 AP; 3.4.5 SEAP; 3.4.6 β-Lactamase; 3.4.7 Luciferase; 3.4.8 GFP; 3.5 Reporter Gene Assay Systems for the Investigation of GPCRs; 3.5.1 Application of Luciferase as a Reporter Gene; 3.5.2 Application of other Reporter Genes for the Investigation of GPCRs; References; 4 From the Human Genome to New Drugs: The Potential of Orphan G-protein-coupled Receptors 4.1 Introduction |
| Record Nr. | UNINA-9910146243903321 |
| Weinheim, : Wiley-VCH, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Molecular biology in medicinal chemistry [[electronic resource] /] / edited by Th. Dingermann, D. Steinhilber and G. Folkers
| Molecular biology in medicinal chemistry [[electronic resource] /] / edited by Th. Dingermann, D. Steinhilber and G. Folkers |
| Pubbl/distr/stampa | Weinheim, : Wiley-VCH, 2004 |
| Descrizione fisica | 1 online resource (437 p.) |
| Disciplina | 615.19 |
| Altri autori (Persone) |
DingermannTheodor
FolkersGerd SteinhilberDieter <1959-> |
| Collana | Methods and principles in medicinal chemistry |
| Soggetto topico |
Chiral drugs
Genomics Molecular biology Molecular pharmacology Pharmacogenomics |
| ISBN |
1-280-52027-2
9786610520275 3-527-60518-5 3-527-60266-6 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Molecular Biology in Medicinal Chemistry; Contents; Preface; Foreword; Contributors; Part I Molecular Targets; 1 Cellular Assays in Drug Discovery; 1.1 Introduction; 1.1.1 Positioning Cellular Assays; 1.1.2 Impact on Drug Discovery; 1.1.3 Classification of Cellular Assays; 1.1.4 Progress in Tools and Technologies for Cellular Compound Profiling; 1.2 Membrane Proteins and Fast Cellular Responses; 1.2.1 Receptors; 1.2.1.1 FLIPR Technology for Detection of Intracellular Calcium Release; 1.2.1.2 Competitive Immunoassay for Detection of Intracellular cAMP
1.2.1.3 Enzyme Fragment Complementation (EFC) Technology1.2.2 Membrane Transport Proteins; 1.2.2.1 Ion Channels; 1.2.2.2 MDR Proteins; 1.3 Gene and Protein Expression Profiling in High-throughput Formats; 1.3.1 Reporter Gene Assays in Lead Finding; 1.3.2 Reporter Gene Assays in Lead Optimization; 1.4 Spatio-temporal Assays and Subpopulation Analysis; 1.4.1 Phosphorylation Stage-specific Antibodies; 1.4.2 Target-protein-specific Antibodies; 1.4.3 Protein-GFP Fusions; 1.4.4 Fluorescence Resonance Energy Transfer (FRET) 1.4.5 GPCR Activation using Bioluminescence Resonance Energy Transfer (BRET)1.4.6 Protein Fragment Complementation Assays (PCA); 1.5 Phenotypic Assays; 1.5.1 Proliferation/Respiration/Toxicity; 1.5.2 Apoptosis; 1.5.3 Differentiation; 1.5.4 Monitoring Cell Metabolism; 1.5.5 Other Phenotypic Assays; Acknowledgments; References; 2 Gene Knockout Models; 2.1 Introduction; 2.2 Gene Knockout Mice; 2.2.1 ES Cells; 2.2.2 Targeting Vector; 2.2.3 Selection of Recombinant ES Cells; 2.2.4 Injection of Recombinant ES Cells into Blastocysts and Blastocyst Transfer to Pseudopregnant Recipients 2.2.5 Chimeras and F1 and F2 Offspring2.3 Tissue-Specific Gene Expression; 2.3.1 Ligand-Activated CRE Recombinases; 2.3.2 The Tetracycline/Doxycycline-Inducible Expression System; 2.4 Transgenic Mice; 2.5 Targeted Gene Disruption in Drosophila; 2.6 Targeted Gene Knockdown in Zebrafish; 2.7 Targeted Caenorhabditis Elegans Deletion Strains; References; 3 Reporter Gene Assay Systems for the Investigation of G-protein-coupled Receptors; 3.1 Receptors and Cellular Communication; 3.1.1 Ion Channel-linked Receptors; 3.1.2 Enzyme-linked Cell-surface Receptors; 3.1.3 GPCRs 3.2 Affinity and Activity of GPCR Ligands3.3 The Role of Transcription Factors in Gene Expression; 3.3.1 CREB; 3.3.2 SRF; 3.3.3 STAT Proteins; 3.3.4 c-Jun; 3.3.5 NF-AT; 3.4 Reporter Genes; 3.4.1 CAT; 3.4.2 β-Gal; 3.4.3 β-Glucuronidase; 3.4.4 AP; 3.4.5 SEAP; 3.4.6 β-Lactamase; 3.4.7 Luciferase; 3.4.8 GFP; 3.5 Reporter Gene Assay Systems for the Investigation of GPCRs; 3.5.1 Application of Luciferase as a Reporter Gene; 3.5.2 Application of other Reporter Genes for the Investigation of GPCRs; References; 4 From the Human Genome to New Drugs: The Potential of Orphan G-protein-coupled Receptors 4.1 Introduction |
| Record Nr. | UNINA-9910830570303321 |
| Weinheim, : Wiley-VCH, 2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
| ||
Soggetto topico
-
Chiral drugs
(13)
- Drug development (7)
- Molecular pharmacology (5)
- Drugs - Research (3)
- Genomics (3)