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Development of in-tether carbon chiral center-induced helical peptide : methodology and applications / / Kuan Hu
| Development of in-tether carbon chiral center-induced helical peptide : methodology and applications / / Kuan Hu |
| Autore | Hu Kuan |
| Edizione | [1st ed. 2021.] |
| Pubbl/distr/stampa | Singapore : , : Springer, , [2021] |
| Descrizione fisica | 1 online resource (XV, 102 p. 75 illus., 65 illus. in color.) |
| Disciplina | 547.756 |
| Collana | Springer Theses |
| Soggetto topico |
Peptides - Synthesis
Cancer - Research Peptides - Biotechnology Chemistry Techniques, Synthetic Peptides - therapeutic use Peptides, Cyclic Biomedical Research |
| ISBN | 981-336-613-3 |
| Formato | Materiale a stampa  |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto | Introduction -- Method to construct in-tether chiral center constrained helical peptide -- Application in disrupting p53/MDM2 protein-protein interactions -- Fabrication of nanomaterials with in-tether chiral center constrained helical peptide. |
| Record Nr. | UNINA-9910484381203321 |
Hu Kuan
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| Singapore : , : Springer, , [2021] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Greene's protective groups in organic synthesis / / Peter G. M. Wuts
| Greene's protective groups in organic synthesis / / Peter G. M. Wuts |
| Autore | Wuts Peter G. M. |
| Edizione | [6th ed.] |
| Pubbl/distr/stampa | Hoboken, NJ : , : John Wiley & Sons, Incorporated, , [2025] |
| Descrizione fisica | 1 online resource (1804 pages) : illustrations |
| Disciplina | 547.2 |
| Soggetto topico |
Protective groups (Chemistry)
Organic compounds - Synthesis Chemistry, Organic - Methodology Chemistry Techniques, Synthetic Organic Chemicals Chemistry, Organic - methods |
| ISBN |
9781394233182
1394233183 9781394233199 1394233191 9781394233175 1394233175 |
| Formato | Materiale a stampa |
| Livello bibliografico | Monografia |
| Lingua di pubblicazione | eng |
| Nota di contenuto |
Cover -- Volume 1 -- Title Page -- Copyright Page -- Dedication -- Contents -- Preface -- Abbreviations -- Chapter 1 The Role of Protective Groups in Organic Synthesis -- Properties of a Protective Group -- Historical Development -- Development of New Protective Groups -- Selection of a Protective Group from This Book -- Synthesis of Complex Substances. Two Examples (As Used in the Synthesis of Himastatin and Palytoxin) of the Selection, Introduction, and Removal of Protective Groups -- Synthesis of Himastatin -- Synthesis of Palytoxin Carboxylic Acid -- Chapter 2 Protection for the Hydroxyl Group Including 1,2- and 1,3-Diols -- Ethers -- Substituted Methyl Ethers -- Substituted Ethyl Ethers -- Methoxy-Substituted Benzyl Ethers -- Silyl Ethers -- Migration of Silyl Groups -- Cleavage -- Esters -- Proximity Assisted Deprotection for Ester Cleavage -- Miscellaneous Esters -- Sulfonates, Sulfenates and Sulfinates as Protective Groups for Alcohols -- Carbonates -- Carbamate Protection of Alcohols -- Protection for 1,2-and 1,3-Diols -- Monoprotection of Diols -- Cyclic Acetals and Ketals -- Chiral Ketones -- Cyclic Ortho Esters -- Silyl Derivatives -- Cyclic Carbonates -- Cyclic Boronates -- Chapter 3 Protection for Phenols and Catechols -- Protection for Phenols and Catechols -- Ethers -- Silyl Ethers -- Esters -- Carbonates -- Carbamates -- Phosphinates -- Sulfonates -- Protection for Catechols (1,2-Dihydroxybenzenes) -- Cyclic Acetals and Ketals -- Cyclic Esters -- Protection for 2-Hydroxybenzenethiols -- Chapter 4 Protection for the Carbonyl Group -- Acetals and Ketals -- Acyclic Acetals and Ketals -- Cyclic Acetals and Ketals -- Chiral Acetals and Ketals -- Dithio Acetals and Ketals -- Acyclic Dithio Acetals and Ketals -- Cyclic Dithio Acetals and Ketals -- Monothio Acetals and Ketals -- Acyclic Monothio Acetals and Ketals.
Cyclic Monothio Acetals and Ketals -- Miscellaneous Derivatives -- O-Substituted Cyanohydrins -- Substituted Hydrazones -- 1,2-Adducts to Aldehydes and Ketones -- Protection of the Carbonyl Group as an Enolate Anions, Enol Ethers, Enamines, and Imines -- Lithium Diisopropylamide (LDA) -- Monoprotection of Dicarbonyl Compounds -- Selective Protection of -and -Diketones -- Cyclic Ketals, Monothio, and Dithio Ketals -- Chapter 5 Protection for the Carboxyl Group -- Esters -- General Preparations of Esters -- General Cleavage of Esters -- Transesterification -- Enzymatically Cleavable Esters -- Substituted Methyl Esters -- 2-Substituted Ethyl Esters -- Substituted Benzyl Esters -- Silyl Esters -- Activated Esters -- Miscellaneous Derivatives -- Stannyl Esters -- Amides and Hydrazides -- Amides -- Protection of Sulfonic Acids -- Protection of Boronic Acids -- Chapter 6 Protection for the Thiol Group -- Thioethers -- S-Diphenylmethyl, Substituted S-Diphenylmethyl, and S-Triphenylmethyl Thioethers -- 4-Methoxytrityl (Mtt.SR) Thioether -- Substituted S-Methyl Derivatives: Monothio, Dithio, and Aminothio Acetals -- Substituted S-Ethyl Derivatives -- Silyl Thioethers -- Thioesters -- Thiocarbonate Derivatives -- Thiocarbamate Derivatives -- Miscellaneous Derivatives -- Unsymmetrical Disulfides -- Sulfenyl Derivatives -- Protection for Dithiols: Dithio Acetals and Ketals -- Protection for Sulfides -- S-P Derivatives -- Protection for the Amino Thiol Group -- Protection for Selenols -- Volume 2 -- Title Page -- Copyright Page -- Dedication -- Contents -- Preface -- Abbreviations -- Chapter 7 Protection for the Amino Group -- Introduction to Amines -- Carbamates -- Substituted Ethyl Carbamates -- Carbamates Cleaved by a 1,6-Elimination -- Cleavage by -Elimination -- Photolytically Cleaved Carbamates -- Miscellaneous Carbamates -- Urea-Type Derivatives -- Amides. Transamidation -- Assisted Cleavage of Amides -- Amide Cleavage Induced by Nitro Group Reduction -- Amide Cleavage Induced by Release of an Alcohol -- Amides Cleaved by Other Chemical Reactions -- Bisprotection of Amines -- Special -NH Protective Groups -- N-Alkyl and N-Aryl Amines -- Imine Derivatives -- Enamine Derivatives -- N-Heteroatom Derivatives -- N-Metal Derivatives -- N-N Derivatives -- N-P Derivatives -- N-Si Derivatives -- N-S Derivatives -- N-Sulfenyl Derivatives -- Protection of Amino Alcohols -- Protection for Imidazoles, Pyrroles, Indoles, and Other Aromatic Heterocycles -- N-Sulfonyl Derivatives -- Carbamates -- N-Alkyl and N-Aryl Derivatives -- Amino Acetal Derivatives -- Amides -- Protection for the Amide -NH -- Amides -- Protection for the Sulfonamide -NH -- Chapter 8 Protection for the Alkyne -CH -- Chapter 9 Protection for the Phosphate Group -- Introduction -- Some General Methods for Phosphate Ester Formation -- Removal of Protective Groups from Phosphorus -- Alkyl Phosphates -- Phosphates Cleaved by Cyclodeesterification -- 2-Substituted Ethyl Phosphates -- Haloethyl Phosphates -- Benzyl Phosphates -- Phenyl Phosphates -- Photochemically Cleaved Phosphate Protective Groups -- Amidates -- Miscellaneous Derivatives -- Chapter 10 Protecting Group Effects in Carbohydrate Chemistry -- Introduction -- Early Observations Protecting Group-Induced Reactivity -- Relative Reactivities -- Fraser-Reidfs Concept of Armed and Disarmed -- Examples of How Protecting Groups Arm and Disarm Glycosides -- Aglycone Transfer -- Participating Groups -- Ester at the C-2 Hydroxyl -- Esters at Positions Other Than 2 -- Ethers Primarily at the C-2 Hydroxyl -- Conformational Restriction -- Benzylidene Group and other Acetals -- Directing Effect of Silylene Groups -- Carbonates as Conformational Restrictors -- Orthoester Conformational Restriction. Silyl Groups: Conformational and Reactivity Effect -- Studies on the Conformational Flip Using Silyl Groups -- Amino Sugar Protection -- Imine Protection -- Protection of the NH2 as An Azide -- Imide Protection -- Oxazolidinones -- Introduction to the Formation of Sialyl Glycosides -- Amides and Their Effects -- Protecting Group Effects in the Glycosylation of 2-Deoxy Sugars -- Furanosides -- Protecting Group Effects on Acceptors -- C-Glycosylation -- Sphingolipids -- Introduction -- Chapter 11 Reactivities, Reagents, and Reactivity Charts -- Reactivities -- Reagents -- Reactivity Charts -- Reactivity Chart 1. Protection for Hydroxyl Group: Ethers -- Reactivity Chart 2. Protection for Hydroxyl Group: Esters -- Reactivity Chart 3. Protection for 1,2-and 1,3-Diols -- Reactivity Chart 4. Protection for Phenols and Catechols -- Reactivity Chart 5. Protection for the Carbonyl Group -- Reactivity Chart 6. Protection for the Carboxyl Group -- Reactivity Chart 7. Protection for the Thiol Group -- Reactivity Chart 8. Protection for the Amino Group: Carbamates -- Reactivity Chart 9. Protection for the Amino Group: Amides -- Reactivity Chart 10. Protection for the Amino Group: Special -NH Protective Groups -- Reactivity Chart 11. Selective Deprotection of Silyl Ethers -- Index -- EULA. |
| Altri titoli varianti | Protective groups in organic synthesis |
| Record Nr. | UNINA-9911019677803321 |
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Wuts Peter G. M.
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| Hoboken, NJ : , : John Wiley & Sons, Incorporated, , [2025] | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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SynOpen
| SynOpen |
| Pubbl/distr/stampa | [Stuttgart], : Georg Thieme Verlag, [2017]- |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry Chemistry Techniques, Synthetic |
| Soggetto genere / forma |
Periodicals.
Periodical |
| ISSN | 2509-9396 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996321225003316 |
| [Stuttgart], : Georg Thieme Verlag, [2017]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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SynOpen
| SynOpen |
| Pubbl/distr/stampa | [Stuttgart], : Georg Thieme Verlag, [2017]- |
| Descrizione fisica | 1 online resource |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry Chemistry Techniques, Synthetic |
| Soggetto genere / forma |
Periodical
Periodicals. Zeitschrift |
| ISSN | 2509-9396 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910137103403321 |
| [Stuttgart], : Georg Thieme Verlag, [2017]- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthesis and reactivity in inorganic and metal-organic chemistry [[electronic resource]]
| Synthesis and reactivity in inorganic and metal-organic chemistry [[electronic resource]] |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, -c2004 |
| Disciplina | 541 |
| Soggetto topico |
Inorganic compounds - Synthesis
Organic compounds - Synthesis Organometallic compounds - Synthesis Reactivity (Chemistry) Organometallic Compounds - chemistry Chemistry Techniques, Synthetic |
| ISSN | 1532-2440 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996215600703316 |
| New York, NY, : Marcel Dekker, -c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Synthesis and reactivity in inorganic and metal-organic chemistry
| Synthesis and reactivity in inorganic and metal-organic chemistry |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker, -c2004 |
| Disciplina | 541 |
| Soggetto topico |
Inorganic compounds - Synthesis
Organic compounds - Synthesis Organometallic compounds - Synthesis Reactivity (Chemistry) Organometallic Compounds - chemistry Chemistry Techniques, Synthetic |
| ISSN | 1532-2440 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910231846203321 |
| New York, NY, : Marcel Dekker, -c2004 | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Synthetic communications [[electronic resource]]
| Synthetic communications [[electronic resource]] |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker |
| Disciplina | 547.2 |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry, Organic Chemistry Techniques, Synthetic |
| ISSN | 1532-2432 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996201383903316 |
| New York, NY, : Marcel Dekker | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Synthetic communications
| Synthetic communications |
| Pubbl/distr/stampa | New York, NY, : Marcel Dekker |
| Disciplina | 547.2 |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry, Organic Chemistry Techniques, Synthetic |
| ISSN | 1532-2432 |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910231850803321 |
| New York, NY, : Marcel Dekker | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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Tetrahedron chem
| Tetrahedron chem |
| Pubbl/distr/stampa | [London] : , : Elsevier Ltd., , 2022- |
| Descrizione fisica | online resource |
| Disciplina | 540 |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry, Organic Chemistry Techniques, Synthetic |
| Soggetto genere / forma | Periodicals. |
| ISSN | 2666-951X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNISA-996466969503316 |
| [London] : , : Elsevier Ltd., , 2022- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. di Salerno | ||
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Tetrahedron chem
| Tetrahedron chem |
| Pubbl/distr/stampa | [London] : , : Elsevier Ltd., , 2022- |
| Descrizione fisica | online resource |
| Disciplina | 540 |
| Soggetto topico |
Organic compounds - Synthesis
Chemistry, Organic Chemistry Techniques, Synthetic |
| Soggetto genere / forma |
Periodical
Periodicals. |
| ISSN | 2666-951X |
| Formato | Materiale a stampa |
| Livello bibliografico | Periodico |
| Lingua di pubblicazione | eng |
| Record Nr. | UNINA-9910513710303321 |
| [London] : , : Elsevier Ltd., , 2022- | ||
| Materiale a stampa | ||
| Lo trovi qui: Univ. Federico II | ||
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