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Biblioteca

MARC Lista (tabellare)
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Descrizione fisica 1 online resource (430 pages) : illustrations, tables
Disciplina 543.01
Soggetto topico Chemistry, Analytic - Technique
Extraction (Chemistry)
Soggetto genere / forma Electronic books.
ISBN 1-68108-379-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910164058103321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Descrizione fisica 1 online resource (430 pages) : illustrations, tables
Disciplina 543.01
Soggetto topico Chemistry, Analytic - Technique
Extraction (Chemistry)
ISBN 1-68108-379-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910792627303321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Analytical microextraction techniques / / edited by M. Valcarcel, S. Cardenas, R. Lucena
Pubbl/distr/stampa Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Descrizione fisica 1 online resource (430 pages) : illustrations, tables
Disciplina 543.01
Soggetto topico Chemistry, Analytic - Technique
Extraction (Chemistry)
ISBN 1-68108-379-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910812755903321
Sharjah, United Arab Emirates : , : Bentham Science Publishers, , 2017
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Comparative evaluation of chemical ranking and scoring methodologies / / prepared by University of Tennessee, Center for Clean Products and Clean Technologies: Gary A. Davis, Mary Swanson, Sheila Jones
Comparative evaluation of chemical ranking and scoring methodologies / / prepared by University of Tennessee, Center for Clean Products and Clean Technologies: Gary A. Davis, Mary Swanson, Sheila Jones
Pubbl/distr/stampa [Knoxville, Tenn.] : , : [U.S. Environmental Protection Agency], , 1994
Descrizione fisica 1 online resource (v, 56 pages)
Altri autori (Persone) DavisGary A <1952-> (Gary Allen)
SwansonMary B <1962-> (Mary Beth)
JonesSheila
Soggetto topico Analytical chemistry - Technique
Chemicals
Toxicology
Biological exposure indices (Industrial toxicology)
Chemistry, Analytic - Technique
Soggetto genere / forma Comparative studies.
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910707279003321
[Knoxville, Tenn.] : , : [U.S. Environmental Protection Agency], , 1994
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Handbook of analytical techniques
Handbook of analytical techniques
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2001
Disciplina 543
Soggetto topico Chemistry, Analytic - Technique
Analytical Chemistry
Chemistry
Physical Sciences & Mathematics
ISBN 3-527-61832-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910144372703321
[Place of publication not identified], : Wiley VCH, 2001
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Handbook of analytical techniques
Handbook of analytical techniques
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2001
Disciplina 543
Soggetto topico Chemistry, Analytic - Technique
Analytical Chemistry
Chemistry
Physical Sciences & Mathematics
ISBN 3-527-61832-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910829970103321
[Place of publication not identified], : Wiley VCH, 2001
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Handbook of analytical techniques
Handbook of analytical techniques
Pubbl/distr/stampa [Place of publication not identified], : Wiley VCH, 2001
Disciplina 543
Soggetto topico Chemistry, Analytic - Technique
Analytical Chemistry
Chemistry
Physical Sciences & Mathematics
ISBN 3-527-61832-5
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Record Nr. UNINA-9910841562303321
[Place of publication not identified], : Wiley VCH, 2001
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Edizione [2nd ed.]
Pubbl/distr/stampa Chichester, West Sussex, : Wiley, 2010
Descrizione fisica 1 online resource (583 p.)
Disciplina 660.29
Altri autori (Persone) BakeevKatherine A
Soggetto topico Chemistry, Technical
Chemistry, Analytic - Technological innovations
Chemistry, Analytic - Technique
Spectrum analysis
Pharmaceutical chemistry
Soggetto genere / forma Electronic books.
ISBN 1-282-68941-X
9786612689413
0-470-68959-5
0-470-68960-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Machine generated contents note: Chapter 1 -- Overview of Process Analysis and PAT -- Jason E. Dickens -- 1.1 Introduction -- 1.2 Execution of Process Analysis Projects -- 1.3 Process Instrumentation -- 1.4 Conclusions -- 1.5 Glossy of Acronyms and Terms -- 1.6 References -- Chapter 2 -- Implementation of Process Analytical Technologies -- Robert Guenard and Gert Thurau -- 2.1 Introduction to implementation of process analytical technologies (PAT) in the industrial setting -- 2.2 Generalized process analytics work process -- 2.3 Considerations for PAT implementation in the pharmaceutical industry -- 2.4 Conclusions -- 2.5 References -- Chapter 3 -- Process Sampling: Theory of Sampling - the missing link in Process Analytical Technologies (PAT) -- Kim H. Esbensen and Peter Paasch-Mortensen -- 3.1 Introduction -- 3.2 Theory of Sampling TOS - introduction -- 3.3 Mass reduction as a specific sampling procedure -- 3.4 Fundamental Sampling Principle (FSP) -- 3.5 Sampling - a very practical issue -- 3.6 Reactors vessels - identical process sampling issues -- 3.7 Heterogeneity characterisaton of 1-d lots: variography -- 3.8 Data Quality - new insight from THE TOS -- 3.9 Validation in chemometrics AND PAT -- 3.10 Summary -- References -- Chapter 4 -- UV-visible spectroscopy for On-Line Analysis -- Marcel A. Liauw, Lewis C. Baylor and Patrick E. O'Rourke -- 4.1 Introduction -- 4.2 Theory -- 4.3 Instrumentation -- 4.4 Sample interface -- 4.5 Implementation -- 4.6 Applications -- 4.7 Detailed application notes -- 4.8 Conclusion -- References -- Chapter 5 -- Near-infrared Spectroscopy for Process Analytical Technology : Theory, Technology and Implementation -- Michael B. Simpson -- 5.1 Introduction -- 5.2 Theory of near-infrared spectroscopy -- 5.3 Analyser technologies in the near-infrared -- 5.4 The sampling interface -- 5.5 Practical examples of near-infrared analytical applications -- 5.6 Conclusion -- References --
Chapter 6 -- Infrared Spectroscopy for Process Analytical Applications -- John P. Coates -- 6.1 Introduction -- 6.2 Practical aspects of IR Spectroscopy -- 6.3 Instrumentation Design and Technology -- 6.4 Process IR Instrumentation -- 6.5 Applications of Process IR Analyzers -- 6.6 Process IR Analyzers: A Review -- 6.7 Trends and Directions -- Abbreviations and Acronyms -- References -- Chapter 7 -- Raman Spectroscopy -- Dr. Nancy L. Jestel -- 7.1 Attractive features of Raman spectroscopy -- 7.2 Potential issues with Raman spectroscopy -- 7.3 Fundamentals of Raman spectroscopy -- 7.4 Raman instrumentation -- 7.5 Quantitative Raman -- 7.6 Applications -- 7.7 Current state of process Raman spectroscopy -- 7.8 References -- Chapter 8 -- Near-Infrared Chemical Imaging for Product and Process Understanding -- E. Neil Lewis, Joseph W. Schoppelrei, Lisa Makein, Linda H. Kidder and Eunah Lee -- 8.1 The PAT initiative -- 8.2 The role of near-infrared chemical imaging (NIR-CI) in the pharmaceutical industry -- 8.3 Evolution of NIR imaging instrumentation -- 8.4 Chemical imaging principles -- 8.5 PAT applications -- 8.6 Processing case study one: estimating 'abundance' of sample components -- 8.7 Processing case study two: determining blend homogeneity through statistical analysis -- 8.8 Final thoughts -- Acknowledgements -- Chapter 9: -- Acoustic chemometric monitoring of industrial production processes -- Maths Halstensen & Kim H. Esbensen -- 9.1 What is acoustic chemometrics? -- 9.2 How acoustic chemometrics works -- 9.3 Industrial production process monitoring -- 9.4 Available on-line acoustic chemometric equipment -- 9.5 Discussion -- 9.6 Conclusions -- 9.7 References -- Chapter 10 -- Process NMR Spectroscopy: Technology and On-line Applications -- John C. Edwards, Ph.D. and Paul J. Giammatteo, Ph.D. -- 10.1 Introduction -- 10.2NMR Spectroscopy Overview -- 10.3 Process NMR Instrumentation -- 10.4 Postprocessing methodologies for NMR data -- 10.5 Advantages and limitations of NMR as a process analytical technology -- 10.6 On-line and at-line applications -- 10.7 Current Development and Applications -- 10.8 Conclusions -- References --
Chapter 11 -- Fluorescent Sensing and Process Analytical Applications -- Jason E. Dickens -- 11.1 Introduction -- 11.2 Luminescence fundamentals -- 11.3 LIF sensing fundamentals -- 11.4 LIF sensing instrumentation -- 11.5 Luminescent detection risks -- 11.6 Process analytical technology applications -- 11.7 Conclusions -- References -- Chapter 12 -- Chemometrics in Process Analytical Technology (PAT) -- Charles E. Miller -- 12.1 Introduction -- 12.2 Foundations of Chemometrics -- 12.3 Chemometric Methods in PAT -- 12.4 Overfitting and Model Validation -- 12.5 Outliers -- 12.6 Calibration Strategies in PAT -- 12.7 Sample and Variable Selection in Chemometrics -- 12.8 Troubleshooting/Improving an Existing Method -- 12.9 Calibration Transfer and Instrument Standardization -- 12.10 Chemometric Model Deployment Issues in PAT -- 12.11 People Issues -- 12.12 The Final Word -- Chapter 13 -- On-line PAT Applications of Spectroscopy in the Pharmaceutical Industry -- Brandye Smith-Goettler -- 13.1 Background -- 13.2 Reaction monitoring -- 13.3 Crystallization -- 13.4 API drying -- 13.5 Nanomilling -- 13.6 Hot-melt extrusion -- 13.7 Granulation -- 13.8 Powder blending -- 13.9 Compression -- 13.10 Coating -- 13.11 Biologics -- 13.12 Cleaning validation -- 13.13 Conclusions -- References -- Chapter 14 -- NIR spectroscopy in pharmaceutical analysis: Off-line and At-line PAT Applications -- Prof. Marcelo Blanco Romi;a -- 14.1 Introduction -- 14.2 Foundation of qualitative method development -- 14.3 Foundation of quantitative method development -- 14.4 Method validation -- 14.5 Calibration transfer -- 14.6 Pharmaceutical applications -- 14.7 Conclusions -- Chapter 15 -- Near-Infrared Spectroscopy (NIR) as a PAT tool in the Chemical Industry: Added value and implementation challenges -- Ann M. Brearley and Susan J. Foulk -- 15.1 Introduction -- 15.2 Successful process analyzer implementation -- 15.3 Example applications -- Chapter 16 -- Future trends for PAT for increased process understanding and growing applications in biomanufacturing -- Katherine A. Bakeev and Jose C. Menezes -- 16.1 Introduction -- 16.2 Regulatory Guidance and its Impact on PAT -- 16.3 Going Beyond Process Analyzers Towards Solutions -- 16.4 Emerging Application Areas of PAT -- 16.5 New and Emerging Sensor and Control Technologies -- 16.6 Advances in sampling: NeSSI[trademark symbol] -- 16.7 Challenges Ahead -- 16.8 Conclusion -- References.
Record Nr. UNINA-9910139515903321
Chichester, West Sussex, : Wiley, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Edizione [2nd ed.]
Pubbl/distr/stampa Chichester, West Sussex, : Wiley, 2010
Descrizione fisica 1 online resource (583 p.)
Disciplina 660.29
Altri autori (Persone) BakeevKatherine A
Soggetto topico Chemistry, Technical
Chemistry, Analytic - Technological innovations
Chemistry, Analytic - Technique
Spectrum analysis
Pharmaceutical chemistry
ISBN 1-282-68941-X
9786612689413
0-470-68959-5
0-470-68960-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Machine generated contents note: Chapter 1 -- Overview of Process Analysis and PAT -- Jason E. Dickens -- 1.1 Introduction -- 1.2 Execution of Process Analysis Projects -- 1.3 Process Instrumentation -- 1.4 Conclusions -- 1.5 Glossy of Acronyms and Terms -- 1.6 References -- Chapter 2 -- Implementation of Process Analytical Technologies -- Robert Guenard and Gert Thurau -- 2.1 Introduction to implementation of process analytical technologies (PAT) in the industrial setting -- 2.2 Generalized process analytics work process -- 2.3 Considerations for PAT implementation in the pharmaceutical industry -- 2.4 Conclusions -- 2.5 References -- Chapter 3 -- Process Sampling: Theory of Sampling - the missing link in Process Analytical Technologies (PAT) -- Kim H. Esbensen and Peter Paasch-Mortensen -- 3.1 Introduction -- 3.2 Theory of Sampling TOS - introduction -- 3.3 Mass reduction as a specific sampling procedure -- 3.4 Fundamental Sampling Principle (FSP) -- 3.5 Sampling - a very practical issue -- 3.6 Reactors vessels - identical process sampling issues -- 3.7 Heterogeneity characterisaton of 1-d lots: variography -- 3.8 Data Quality - new insight from THE TOS -- 3.9 Validation in chemometrics AND PAT -- 3.10 Summary -- References -- Chapter 4 -- UV-visible spectroscopy for On-Line Analysis -- Marcel A. Liauw, Lewis C. Baylor and Patrick E. O'Rourke -- 4.1 Introduction -- 4.2 Theory -- 4.3 Instrumentation -- 4.4 Sample interface -- 4.5 Implementation -- 4.6 Applications -- 4.7 Detailed application notes -- 4.8 Conclusion -- References -- Chapter 5 -- Near-infrared Spectroscopy for Process Analytical Technology : Theory, Technology and Implementation -- Michael B. Simpson -- 5.1 Introduction -- 5.2 Theory of near-infrared spectroscopy -- 5.3 Analyser technologies in the near-infrared -- 5.4 The sampling interface -- 5.5 Practical examples of near-infrared analytical applications -- 5.6 Conclusion -- References --
Chapter 6 -- Infrared Spectroscopy for Process Analytical Applications -- John P. Coates -- 6.1 Introduction -- 6.2 Practical aspects of IR Spectroscopy -- 6.3 Instrumentation Design and Technology -- 6.4 Process IR Instrumentation -- 6.5 Applications of Process IR Analyzers -- 6.6 Process IR Analyzers: A Review -- 6.7 Trends and Directions -- Abbreviations and Acronyms -- References -- Chapter 7 -- Raman Spectroscopy -- Dr. Nancy L. Jestel -- 7.1 Attractive features of Raman spectroscopy -- 7.2 Potential issues with Raman spectroscopy -- 7.3 Fundamentals of Raman spectroscopy -- 7.4 Raman instrumentation -- 7.5 Quantitative Raman -- 7.6 Applications -- 7.7 Current state of process Raman spectroscopy -- 7.8 References -- Chapter 8 -- Near-Infrared Chemical Imaging for Product and Process Understanding -- E. Neil Lewis, Joseph W. Schoppelrei, Lisa Makein, Linda H. Kidder and Eunah Lee -- 8.1 The PAT initiative -- 8.2 The role of near-infrared chemical imaging (NIR-CI) in the pharmaceutical industry -- 8.3 Evolution of NIR imaging instrumentation -- 8.4 Chemical imaging principles -- 8.5 PAT applications -- 8.6 Processing case study one: estimating 'abundance' of sample components -- 8.7 Processing case study two: determining blend homogeneity through statistical analysis -- 8.8 Final thoughts -- Acknowledgements -- Chapter 9: -- Acoustic chemometric monitoring of industrial production processes -- Maths Halstensen & Kim H. Esbensen -- 9.1 What is acoustic chemometrics? -- 9.2 How acoustic chemometrics works -- 9.3 Industrial production process monitoring -- 9.4 Available on-line acoustic chemometric equipment -- 9.5 Discussion -- 9.6 Conclusions -- 9.7 References -- Chapter 10 -- Process NMR Spectroscopy: Technology and On-line Applications -- John C. Edwards, Ph.D. and Paul J. Giammatteo, Ph.D. -- 10.1 Introduction -- 10.2NMR Spectroscopy Overview -- 10.3 Process NMR Instrumentation -- 10.4 Postprocessing methodologies for NMR data -- 10.5 Advantages and limitations of NMR as a process analytical technology -- 10.6 On-line and at-line applications -- 10.7 Current Development and Applications -- 10.8 Conclusions -- References --
Chapter 11 -- Fluorescent Sensing and Process Analytical Applications -- Jason E. Dickens -- 11.1 Introduction -- 11.2 Luminescence fundamentals -- 11.3 LIF sensing fundamentals -- 11.4 LIF sensing instrumentation -- 11.5 Luminescent detection risks -- 11.6 Process analytical technology applications -- 11.7 Conclusions -- References -- Chapter 12 -- Chemometrics in Process Analytical Technology (PAT) -- Charles E. Miller -- 12.1 Introduction -- 12.2 Foundations of Chemometrics -- 12.3 Chemometric Methods in PAT -- 12.4 Overfitting and Model Validation -- 12.5 Outliers -- 12.6 Calibration Strategies in PAT -- 12.7 Sample and Variable Selection in Chemometrics -- 12.8 Troubleshooting/Improving an Existing Method -- 12.9 Calibration Transfer and Instrument Standardization -- 12.10 Chemometric Model Deployment Issues in PAT -- 12.11 People Issues -- 12.12 The Final Word -- Chapter 13 -- On-line PAT Applications of Spectroscopy in the Pharmaceutical Industry -- Brandye Smith-Goettler -- 13.1 Background -- 13.2 Reaction monitoring -- 13.3 Crystallization -- 13.4 API drying -- 13.5 Nanomilling -- 13.6 Hot-melt extrusion -- 13.7 Granulation -- 13.8 Powder blending -- 13.9 Compression -- 13.10 Coating -- 13.11 Biologics -- 13.12 Cleaning validation -- 13.13 Conclusions -- References -- Chapter 14 -- NIR spectroscopy in pharmaceutical analysis: Off-line and At-line PAT Applications -- Prof. Marcelo Blanco Romi;a -- 14.1 Introduction -- 14.2 Foundation of qualitative method development -- 14.3 Foundation of quantitative method development -- 14.4 Method validation -- 14.5 Calibration transfer -- 14.6 Pharmaceutical applications -- 14.7 Conclusions -- Chapter 15 -- Near-Infrared Spectroscopy (NIR) as a PAT tool in the Chemical Industry: Added value and implementation challenges -- Ann M. Brearley and Susan J. Foulk -- 15.1 Introduction -- 15.2 Successful process analyzer implementation -- 15.3 Example applications -- Chapter 16 -- Future trends for PAT for increased process understanding and growing applications in biomanufacturing -- Katherine A. Bakeev and Jose C. Menezes -- 16.1 Introduction -- 16.2 Regulatory Guidance and its Impact on PAT -- 16.3 Going Beyond Process Analyzers Towards Solutions -- 16.4 Emerging Application Areas of PAT -- 16.5 New and Emerging Sensor and Control Technologies -- 16.6 Advances in sampling: NeSSI[trademark symbol] -- 16.7 Challenges Ahead -- 16.8 Conclusion -- References.
Record Nr. UNINA-9910830098503321
Chichester, West Sussex, : Wiley, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Process analytical technology [[electronic resource] ] : spectroscopic tools and implementation strategies for the chemical and pharmaceutical industries / / edited by Katherine A. Bakeev
Edizione [2nd ed.]
Pubbl/distr/stampa Chichester, West Sussex, : Wiley, 2010
Descrizione fisica 1 online resource (583 p.)
Disciplina 660.29
Altri autori (Persone) BakeevKatherine A
Soggetto topico Chemistry, Technical
Chemistry, Analytic - Technological innovations
Chemistry, Analytic - Technique
Spectrum analysis
Pharmaceutical chemistry
ISBN 1-282-68941-X
9786612689413
0-470-68959-5
0-470-68960-9
Formato Materiale a stampa
Livello bibliografico Monografia
Lingua di pubblicazione eng
Nota di contenuto Machine generated contents note: Chapter 1 -- Overview of Process Analysis and PAT -- Jason E. Dickens -- 1.1 Introduction -- 1.2 Execution of Process Analysis Projects -- 1.3 Process Instrumentation -- 1.4 Conclusions -- 1.5 Glossy of Acronyms and Terms -- 1.6 References -- Chapter 2 -- Implementation of Process Analytical Technologies -- Robert Guenard and Gert Thurau -- 2.1 Introduction to implementation of process analytical technologies (PAT) in the industrial setting -- 2.2 Generalized process analytics work process -- 2.3 Considerations for PAT implementation in the pharmaceutical industry -- 2.4 Conclusions -- 2.5 References -- Chapter 3 -- Process Sampling: Theory of Sampling - the missing link in Process Analytical Technologies (PAT) -- Kim H. Esbensen and Peter Paasch-Mortensen -- 3.1 Introduction -- 3.2 Theory of Sampling TOS - introduction -- 3.3 Mass reduction as a specific sampling procedure -- 3.4 Fundamental Sampling Principle (FSP) -- 3.5 Sampling - a very practical issue -- 3.6 Reactors vessels - identical process sampling issues -- 3.7 Heterogeneity characterisaton of 1-d lots: variography -- 3.8 Data Quality - new insight from THE TOS -- 3.9 Validation in chemometrics AND PAT -- 3.10 Summary -- References -- Chapter 4 -- UV-visible spectroscopy for On-Line Analysis -- Marcel A. Liauw, Lewis C. Baylor and Patrick E. O'Rourke -- 4.1 Introduction -- 4.2 Theory -- 4.3 Instrumentation -- 4.4 Sample interface -- 4.5 Implementation -- 4.6 Applications -- 4.7 Detailed application notes -- 4.8 Conclusion -- References -- Chapter 5 -- Near-infrared Spectroscopy for Process Analytical Technology : Theory, Technology and Implementation -- Michael B. Simpson -- 5.1 Introduction -- 5.2 Theory of near-infrared spectroscopy -- 5.3 Analyser technologies in the near-infrared -- 5.4 The sampling interface -- 5.5 Practical examples of near-infrared analytical applications -- 5.6 Conclusion -- References --
Chapter 6 -- Infrared Spectroscopy for Process Analytical Applications -- John P. Coates -- 6.1 Introduction -- 6.2 Practical aspects of IR Spectroscopy -- 6.3 Instrumentation Design and Technology -- 6.4 Process IR Instrumentation -- 6.5 Applications of Process IR Analyzers -- 6.6 Process IR Analyzers: A Review -- 6.7 Trends and Directions -- Abbreviations and Acronyms -- References -- Chapter 7 -- Raman Spectroscopy -- Dr. Nancy L. Jestel -- 7.1 Attractive features of Raman spectroscopy -- 7.2 Potential issues with Raman spectroscopy -- 7.3 Fundamentals of Raman spectroscopy -- 7.4 Raman instrumentation -- 7.5 Quantitative Raman -- 7.6 Applications -- 7.7 Current state of process Raman spectroscopy -- 7.8 References -- Chapter 8 -- Near-Infrared Chemical Imaging for Product and Process Understanding -- E. Neil Lewis, Joseph W. Schoppelrei, Lisa Makein, Linda H. Kidder and Eunah Lee -- 8.1 The PAT initiative -- 8.2 The role of near-infrared chemical imaging (NIR-CI) in the pharmaceutical industry -- 8.3 Evolution of NIR imaging instrumentation -- 8.4 Chemical imaging principles -- 8.5 PAT applications -- 8.6 Processing case study one: estimating 'abundance' of sample components -- 8.7 Processing case study two: determining blend homogeneity through statistical analysis -- 8.8 Final thoughts -- Acknowledgements -- Chapter 9: -- Acoustic chemometric monitoring of industrial production processes -- Maths Halstensen & Kim H. Esbensen -- 9.1 What is acoustic chemometrics? -- 9.2 How acoustic chemometrics works -- 9.3 Industrial production process monitoring -- 9.4 Available on-line acoustic chemometric equipment -- 9.5 Discussion -- 9.6 Conclusions -- 9.7 References -- Chapter 10 -- Process NMR Spectroscopy: Technology and On-line Applications -- John C. Edwards, Ph.D. and Paul J. Giammatteo, Ph.D. -- 10.1 Introduction -- 10.2NMR Spectroscopy Overview -- 10.3 Process NMR Instrumentation -- 10.4 Postprocessing methodologies for NMR data -- 10.5 Advantages and limitations of NMR as a process analytical technology -- 10.6 On-line and at-line applications -- 10.7 Current Development and Applications -- 10.8 Conclusions -- References --
Chapter 11 -- Fluorescent Sensing and Process Analytical Applications -- Jason E. Dickens -- 11.1 Introduction -- 11.2 Luminescence fundamentals -- 11.3 LIF sensing fundamentals -- 11.4 LIF sensing instrumentation -- 11.5 Luminescent detection risks -- 11.6 Process analytical technology applications -- 11.7 Conclusions -- References -- Chapter 12 -- Chemometrics in Process Analytical Technology (PAT) -- Charles E. Miller -- 12.1 Introduction -- 12.2 Foundations of Chemometrics -- 12.3 Chemometric Methods in PAT -- 12.4 Overfitting and Model Validation -- 12.5 Outliers -- 12.6 Calibration Strategies in PAT -- 12.7 Sample and Variable Selection in Chemometrics -- 12.8 Troubleshooting/Improving an Existing Method -- 12.9 Calibration Transfer and Instrument Standardization -- 12.10 Chemometric Model Deployment Issues in PAT -- 12.11 People Issues -- 12.12 The Final Word -- Chapter 13 -- On-line PAT Applications of Spectroscopy in the Pharmaceutical Industry -- Brandye Smith-Goettler -- 13.1 Background -- 13.2 Reaction monitoring -- 13.3 Crystallization -- 13.4 API drying -- 13.5 Nanomilling -- 13.6 Hot-melt extrusion -- 13.7 Granulation -- 13.8 Powder blending -- 13.9 Compression -- 13.10 Coating -- 13.11 Biologics -- 13.12 Cleaning validation -- 13.13 Conclusions -- References -- Chapter 14 -- NIR spectroscopy in pharmaceutical analysis: Off-line and At-line PAT Applications -- Prof. Marcelo Blanco Romi;a -- 14.1 Introduction -- 14.2 Foundation of qualitative method development -- 14.3 Foundation of quantitative method development -- 14.4 Method validation -- 14.5 Calibration transfer -- 14.6 Pharmaceutical applications -- 14.7 Conclusions -- Chapter 15 -- Near-Infrared Spectroscopy (NIR) as a PAT tool in the Chemical Industry: Added value and implementation challenges -- Ann M. Brearley and Susan J. Foulk -- 15.1 Introduction -- 15.2 Successful process analyzer implementation -- 15.3 Example applications -- Chapter 16 -- Future trends for PAT for increased process understanding and growing applications in biomanufacturing -- Katherine A. Bakeev and Jose C. Menezes -- 16.1 Introduction -- 16.2 Regulatory Guidance and its Impact on PAT -- 16.3 Going Beyond Process Analyzers Towards Solutions -- 16.4 Emerging Application Areas of PAT -- 16.5 New and Emerging Sensor and Control Technologies -- 16.6 Advances in sampling: NeSSI[trademark symbol] -- 16.7 Challenges Ahead -- 16.8 Conclusion -- References.
Record Nr. UNINA-9910840570803321
Chichester, West Sussex, : Wiley, 2010
Materiale a stampa
Lo trovi qui: Univ. Federico II
Opac: Controlla la disponibilità qui